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James, Aaron Watkins

Title(s)Associate Adjunct Professor, Orthopaedic Surgery
Phone3108251394
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of sensory nerves in cranial bone repair
    NIH/NIDCR R21DE027922Aug 1, 2018 - Jul 31, 2020
    Role: Co-Principal Investigator
    Direct and indirect contributions of perivascular stem cells to bone healing
    NIH/NIAMS R01AR070773Aug 28, 2017 - Jun 30, 2022
    Role: Principal Investigator
    NELL-1 isoforms for the systemic treatment of osteoporosis
    NIH/NIAMS K08AR068316Jul 15, 2015 - Jun 30, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sono T, Hsu CY, Negri S, Miller S, Wang Y, Xu J, Meyers CA, Peault B, James AW. Platelet-derived growth factor receptor-ß (PDGFRß) lineage tracing highlights perivascular cell to myofibroblast transdifferentiation during post-traumatic osteoarthritis. J Orthop Res. 2020 Mar 05. PMID: 32134140.
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    2. Gomez-Salazar M, Gonzalez-Galofre ZN, Casamitjana J, Crisan M, James AW, Péault B. Five Decades Later, Are Mesenchymal Stem Cells Still Relevant? Front Bioeng Biotechnol. 2020; 8:148. PMID: 32185170.
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    3. Sorkin M, Huber AK, Hwang C, Carson WF, Menon R, Li J, Vasquez K, Pagani C, Patel N, Li S, Visser ND, Niknafs Y, Loder S, Scola M, Nycz D, Gallagher K, McCauley LK, Xu J, James AW, Agarwal S, Kunkel S, Mishina Y, Levi B. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020 Feb 05; 11(1):722. PMID: 32024825.
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    4. Hwang C, Marini S, Huber AK, Stepien DM, Sorkin M, Loder S, Pagani CA, Li J, Visser ND, Vasquez K, Garada MA, Li S, Xu J, Hsu CY, Yu PB, James AW, Mishina Y, Agarwal S, Li J, Levi B. Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification. Bone Res. 2019; 7:36. PMID: 31840004.
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    5. Li Z, Meyers CA, Chang L, Lee S, Li Z, Tomlinson R, Hoke A, Clemens TL, James AW. Fracture repair requires TrkA signaling by skeletal sensory nerves. J Clin Invest. 2019 Dec 02; 129(12):5137-5150. PMID: 31638597.
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    6. Ding L, Vezzani B, Khan N, Su J, Xu L, Yan G, Liu Y, Li R, Gaur A, Diao Z, Hu Y, Yang Z, Hardy WR, James AW, Sun H, Péault B. CD10 expression identifies a subset of human perivascular progenitor cells with high proliferation and calcification potentials. Stem Cells. 2020 Feb; 38(2):261-275. PMID: 31721342.
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    7. Wang Y, Xu J, Meyers CA, Gao Y, Tian Y, Broderick K, Peault B, James AW. PDGFRa marks distinct perivascular populations with different osteogenic potential within adipose tissue. Stem Cells. 2020 Feb; 38(2):276-290. PMID: 31742801.
      View in: PubMed
    8. Meyers CA, Xu J, Zhang L, Chang L, Wang Y, Asatrian G, Ding C, Yan N, Zou E, Broderick K, Lee M, Peault B, James AW. Skeletogenic Capacity of Human Perivascular Stem Cells Obtained Via Magnetic-Activated Cell Sorting. Tissue Eng Part A. 2019 12; 25(23-24):1658-1666. PMID: 31020920.
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    9. Hsu CY, Salazar MG, Miller S, Meyers C, Ding C, Hardy W, Péault B, James AW. Comparison of Human Tissue Microarray to Human Pericyte Transcriptome Yields Novel Perivascular Cell Markers. Stem Cells Dev. 2019 09 15; 28(18):1214-1223. PMID: 31264500.
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    10. Ware AD, Brewer N, Meyers C, Morris C, McCarthy E, Shore EM, James AW. Differential Vascularity in Genetic and Nonhereditary Heterotopic Ossification. Int J Surg Pathol. 2019 Jun 28; 1066896919857135. PMID: 31250694.
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    11. James AW, Péault B. Perivascular Mesenchymal Progenitors for Bone Regeneration. J Orthop Res. 2019 06; 37(6):1221-1228. PMID: 30908717.
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    12. Sono T, Meyers CA, Miller D, Ding C, McCarthy EF, James AW. Overlapping features of rapidly progressive osteoarthrosis and Charcot arthropathy. J Orthop. 2019 May-Jun; 16(3):260-264. PMID: 30936675.
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    13. Meyers CA, Sun Z, Chang L, Ding C, Lu A, Ting K, Pang S, James AW. Age dependent effects of NELL-1 isoforms on bone marrow stromal cells. J Orthop. 2019 Mar-Apr; 16(2):175-178. PMID: 30899146.
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    14. Meyers C, Lisiecki J, Miller S, Levin A, Fayad L, Ding C, Sono T, McCarthy E, Levi B, James AW. Heterotopic Ossification: A Comprehensive Review. JBMR Plus. 2019 Apr; 3(4):e10172. PMID: 31044187.
      View in: PubMed
    15. Wang Y, Xu J, Chang L, Meyers CA, Zhang L, Broderick K, Lee M, Peault B, James AW. Relative contributions of adipose-resident CD146+ pericytes and CD34+ adventitial progenitor cells in bone tissue engineering. NPJ Regen Med. 2019; 4:1. PMID: 30622740.
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    16. Chang L, Scott MA, Meyers CA, James AW. Pericytes in Sarcomas and Other Mesenchymal Tumors. Adv Exp Med Biol. 2019; 1147:109-124. PMID: 31147874.
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    17. Sono T, Ware AD, McCarthy EF, James AW. Chondromyxoid Fibroma of the Pelvis: Institutional Case Series With a Focus on Distinctive Features. Int J Surg Pathol. 2019 Jun; 27(4):352-359. PMID: 30580642.
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    18. Meyers CA, Xu J, Asatrian G, Ding C, Shen J, Broderick K, Ting K, Soo C, Peault B, James AW. WISP-1 drives bone formation at the expense of fat formation in human perivascular stem cells. Sci Rep. 2018 10 23; 8(1):15618. PMID: 30353078.
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    19. Zhang L, Chang L, Xu J, Meyers CA, Yan N, Zou E, Ding C, Ting K, Soo C, Pang S, James AW. Frontal Bone Healing Is Sensitive to Wnt Signaling Inhibition via Lentiviral-Encoded Beta-Catenin Short Hairpin RNA. Tissue Eng Part A. 2018 Aug 20. PMID: 29929440.
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    20. Meyers CA, Shen J, Lu A, James AW. WNT16 induces proliferation and osteogenic differentiation of human perivascular stem cells. J Orthop. 2018 Sep; 15(3):854-857. PMID: 30140133.
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    21. Chang L, Zhang L, Xu J, Meyers CA, Li Z, Yan N, Zou E, James AW. Lineage-Specific Wnt Reporter Elucidates Mesenchymal Wnt Signaling during Bone Repair. Am J Pathol. 2018 10; 188(10):2155-2163. PMID: 30031726.
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    22. Shen J, Shrestha S, Rao PN, Asatrian G, Scott MA, Nguyen V, Giacomelli P, Soo C, Ting K, Eilber FC, Peault B, Dry SM, James AW. Corrigendum to "Pericytic mimicry in well-differentiated liposarcoma/atypical lipomatous tumor" (Hum Pathol 2016;54:92-99). Hum Pathol. 2018 08; 78:188. PMID: 29958690.
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    23. Carre AL, Hu MS, James AW, Kawai K, Galvez MG, Longaker MT, Lorenz HP. ß-Catenin-Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding. Plast Reconstr Surg. 2018 03; 141(3):669-678. PMID: 29481398.
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    24. Cocks M, Helmke E, Meyers CA, Fayad L, McCarthy E, James AW. Bizarre parosteal osteochondromatous proliferation: 16 Cases with a focus on histologic variability. J Orthop. 2018 Mar; 15(1):138-142. PMID: 29657458.
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    25. Meyers CA, Casamitjana J, Chang L, Zhang L, James AW, Péault B. Pericytes for Therapeutic Bone Repair. Adv Exp Med Biol. 2018; 1109:21-32. PMID: 30523587.
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    26. Zheng Z, James AW, Li C, Jiang W, Wang JZ, Chang GX, Lee KS, Chen F, Berthiaume EA, Chen Y, Pan HC, Chen EC, Li W, Zhao Z, Zhang X, Ting K, Soo C. Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype. Signal Transduct Target Ther. 2017; 2. PMID: 29201497.
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    27. Meyers CA, Xu J, Zhang L, Asatrian G, Ding C, Yan N, Broderick K, Sacks J, Goyal R, Zhang X, Ting K, Péault B, Soo C, James AW. Early Immunomodulatory Effects of Implanted Human Perivascular Stromal Cells During Bone Formation. Tissue Eng Part A. 2018 03; 24(5-6):448-457. PMID: 28683667.
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    28. James AW, Shen J, Tsuei R, Nguyen A, Khadarian K, Meyers CA, Pan HC, Li W, Kwak JH, Asatrian G, Culiat CT, Lee M, Ting K, Zhang X, Soo C. NELL-1 induces Sca-1+ mesenchymal progenitor cell expansion in models of bone maintenance and repair. JCI Insight. 2017 Jun 15; 2(12). PMID: 28614787.
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    29. Lee S, Wang C, Pan HC, Shrestha S, Meyers C, Ding C, Shen J, Chen E, Lee M, Soo C, Ting K, James AW. Combining Smoothened Agonist and NEL-Like Protein-1 Enhances Bone Healing. Plast Reconstr Surg. 2017 Jun; 139(6):1385-1396. PMID: 28198775.
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    30. Shen J, Chen X, Jia H, Meyers CA, Shrestha S, Asatrian G, Ding C, Tsuei R, Zhang X, Peault B, Ting K, Soo C, James AW. Effects of WNT3A and WNT16 on the Osteogenic and Adipogenic Differentiation of Perivascular Stem/Stromal Cells. Tissue Eng Part A. 2018 01; 24(1-2):68-80. PMID: 28463594.
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    31. James AW, Zhang X, Crisan M, Hardy WR, Liang P, Meyers CA, Lobo S, Lagishetty V, Childers MK, Asatrian G, Ding C, Yen YH, Zou E, Ting K, Peault B, Soo C. Isolation and characterization of canine perivascular stem/stromal cells for bone tissue engineering. PLoS One. 2017; 12(5):e0177308. PMID: 28489940.
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    32. Nguyen V, Meyers CA, Yan N, Agarwal S, Levi B, James AW. BMP-2-induced bone formation and neural inflammation. J Orthop. 2017 Jun; 14(2):252-256. PMID: 28367006.
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    33. Cocks M, Mohan A, Meyers CA, Ding C, Levi B, McCarthy E, James AW. Vascular patterning in human heterotopic ossification. Hum Pathol. 2017 05; 63:165-170. PMID: 28315426.
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    34. Velasco O, Beckett MQ, James AW, Loehr MN, Lewis TG, Hassan T, Janardhanan R. Real-Time Three-Dimensional Echocardiography: Characterization of Cardiac Anatomy and Function-Current Clinical Applications and Literature Review Update. Biores Open Access. 2017; 6(1):15-18. PMID: 28303211.
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    35. Shrestha S, Meyers C, Shen J, Giacomelli P, Scott MA, Soo C, Dry SM, Ting K, James AW. Ang-1 and Ang-2 expression in angiomyolipoma and PEComa family tumors. J Orthop. 2017 Mar; 14(1):154-160. PMID: 28053374.
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    36. Shen J, Meyers CA, James AW. Pericytic mimicry (extravascular migratory metastasis) in neoplasia-reply. Hum Pathol. 2017 05; 63:218. PMID: 27939781.
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    37. Shrestha S, Shen J, Giacomelli P, Scott MA, Soo C, Ting K, Péault B, Dry SM, James AW. Ang-2 but not Ang-1 expression in perivascular soft tissue tumors. J Orthop. 2017 Mar; 14(1):147-153. PMID: 27942190.
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    38. Lee S, Shen J, Pan HC, Shrestha S, Asatrian G, Nguyen A, Meyers C, Nguyen V, Lee M, Soo C, Ting K, James AW. Calvarial Defect Healing Induced by Small Molecule Smoothened Agonist. Tissue Eng Part A. 2016 12; 22(23-24):1357-1366. PMID: 27702396.
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    39. James AW, Shurell E, Singh A, Dry SM, Eilber FC. Malignant Peripheral Nerve Sheath Tumor. Surg Oncol Clin N Am. 2016 10; 25(4):789-802. PMID: 27591499.
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    40. James AW, Hindle P, Murray IR, West CC, Tawonsawatruk T, Shen J, Asatrian G, Zhang X, Nguyen V, Simpson AH, Ting K, Péault B, Soo C. Pericytes for the treatment of orthopedic conditions. Pharmacol Ther. 2017 03; 171:93-103. PMID: 27510330.
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    41. Shen J, Meyers CA, Shrestha S, Singh A, LaChaud G, Nguyen V, Asatrian G, Federman N, Bernthal N, Eilber FC, Dry SM, Ting K, Soo C, James AW. Sclerostin expression in skeletal sarcomas. Hum Pathol. 2016 12; 58:24-34. PMID: 27498059.
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    42. Murakami T, Singh AS, Kiyuna T, Dry SM, Li Y, James AW, Igarashi K, Kawaguchi K, DeLong JC, Zhang Y, Hiroshima Y, Russell T, Eckardt MA, Yanagawa J, Federman N, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2016 Jul 26; 7(30):47556-47564. PMID: 27286459.
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    43. James AW, Chiang M, Asatrian G, Shen J, Goyal R, Chung CG, Chang L, Shrestha S, Turner AS, Seim HB, Zhang X, Wu BM, Ting K, Soo C. Vertebral Implantation of NELL-1 Enhances Bone Formation in an Osteoporotic Sheep Model. Tissue Eng Part A. 2016 06; 22(11-12):840-9. PMID: 27113550.
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    44. Agarwal S, Loder SJ, Sorkin M, Li S, Shrestha S, Zhao B, Mishina Y, James AW, Levi B. Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. Stem Cells. 2016 06; 34(6):1692-701. PMID: 27068890.
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    45. James AW, LaChaud G, Shen J, Asatrian G, Nguyen V, Zhang X, Ting K, Soo C. A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2. Tissue Eng Part B Rev. 2016 08; 22(4):284-97. PMID: 26857241.
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    46. Shen J, Shrestha S, Rao PN, Asatrian G, Scott MA, Nguyen V, Giacomelli P, Soo C, Ting K, Eilber FC, Peault B, Dry SM, James AW. Pericytic mimicry in well-differentiated liposarcoma/atypical lipomatous tumor. Hum Pathol. 2016 08; 54:92-9. PMID: 27063472.
      View in: PubMed
    47. Guo M, James AW, Kwak JH, Shen J, Yokoyama KK, Ting K, Soo CB, Chiu RH. Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption. Sci Rep. 2016 Mar 02; 6:22378. PMID: 26932182.
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    48. Shen J, James AW, Zhang X, Pang S, Zara JN, Asatrian G, Chiang M, Lee M, Khadarian K, Nguyen A, Lee KS, Siu RK, Tetradis S, Ting K, Soo C. Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2. Am J Pathol. 2016 Feb; 186(2):419-34. PMID: 26772960.
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    49. Chang L, Rao N, Bernthal N, Dry SM, James AW. An unusual karyotype in leiomyoma: Case report and literature review. J Orthop. 2015 Dec; 12(Suppl 2):S251-4. PMID: 27047231.
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    50. Shen J, LaChaud G, Shrestha S, Asatrian G, Zhang X, Dry SM, Soo C, Ting K, James AW. NELL-1 expression in tumors of cartilage. J Orthop. 2015 Dec; 12(Suppl 2):S223-9. PMID: 27047227.
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    51. Shen J, Shrestha S, Yen YH, Scott MA, Soo C, Ting K, Peault B, Dry SM, James AW. The pericyte antigen RGS5 in perivascular soft tissue tumors. Hum Pathol. 2016 Jan; 47(1):121-31. PMID: 26558691.
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    52. Lee S, Zhang X, Shen J, James AW, Chung CG, Hardy R, Li C, Girgius C, Zhang Y, Stoker D, Wang H, Wu BM, Peault B, Ting K, Soo C. Brief Report: Human Perivascular Stem Cells and Nel-Like Protein-1 Synergistically Enhance Spinal Fusion in Osteoporotic Rats. Stem Cells. 2015 Oct; 33(10):3158-63. PMID: 26173400.
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    53. James AW, Dry SM. Diagnostically Challenging Epithelioid Soft Tissue Tumors. Surg Pathol Clin. 2015 Sep; 8(3):309-29. PMID: 26297059.
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    54. Shen J, Shrestha S, Yen YH, Scott MA, Asatrian G, Barnhill R, Lugassy C, Soo C, Ting K, Peault B, Dry SM, James AW. Pericyte antigens in angiomyolipoma and PEComa family tumors. Med Oncol. 2015 Aug; 32(8):210. PMID: 26123600.
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    55. James AW, Shen J, Zhang X, Asatrian G, Goyal R, Kwak JH, Jiang L, Bengs B, Culiat CT, Turner AS, Seim Iii HB, Wu BM, Lyons K, Adams JS, Ting K, Soo C. NELL-1 in the treatment of osteoporotic bone loss. Nat Commun. 2015 Jun 17; 6:7362. PMID: 26082355.
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    56. Shen J, Shrestha S, Yen YH, Asatrian G, Mravic M, Soo C, Ting K, Dry SM, Peault B, James AW. Pericyte Antigens in Perivascular Soft Tissue Tumors. Int J Surg Pathol. 2015 Dec; 23(8):638-48. PMID: 26085647.
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    57. Chang L, Nguyen V, Nguyen A, Scott MA, James AW. Pericytes in sarcomas of bone. Med Oncol. 2015 Jul; 32(7):202. PMID: 26076804.
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    58. Chung CG, James AW, Asatrian G, Chang L, Nguyen A, Le K, Bayani G, Lee R, Stoker D, Pang S, Zhang X, Ting K, Péault B, Soo C. Human perivascular stem cell-based bone graft substitute induces rat spinal fusion. Stem Cells Transl Med. 2015 May; 4(5):538. PMID: 25926331.
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    59. Chang L, Shrestha S, LaChaud G, Scott MA, James AW. Review of microRNA in osteosarcoma and chondrosarcoma. Med Oncol. 2015 Jun; 32(6):613. PMID: 25920607.
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    60. Shen J, LaChaud G, Khadarian K, Shrestha S, Zhang X, Soo C, Ting K, Dry SM, James AW. NELL-1 expression in benign and malignant bone tumors. Biochem Biophys Res Commun. 2015 May 01; 460(2):368-74. PMID: 25791475.
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    61. Pang S, Shen J, Liu Y, Chen F, Zheng Z, James AW, Hsu CY, Zhang H, Lee KS, Wang C, Li C, Chen X, Jia H, Zhang X, Soo C, Ting K. Proliferation and osteogenic differentiation of mesenchymal stem cells induced by a short isoform of NELL-1. Stem Cells. 2015 Mar; 33(3):904-15. PMID: 25376942.
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    62. Asatrian G, Pham D, Hardy WR, James AW, Peault B. Stem cell technology for bone regeneration: current status and potential applications. Stem Cells Cloning. 2015; 8:39-48. PMID: 25709479.
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    63. James AW, Chang L, Shrestha S, Tirado CA, Dry SM. An unusual complex karyotype in myopericytoma. J Orthop. 2015 Mar; 12(1):58-62. PMID: 25829759.
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    64. Mravic M, LaChaud G, Nguyen A, Scott MA, Dry SM, James AW. Clinical and histopathological diagnosis of glomus tumor: an institutional experience of 138 cases. Int J Surg Pathol. 2015 May; 23(3):181-8. PMID: 25614464.
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    65. Chang L, Asatrian G, Dry SM, James AW. Circulating tumor cells in sarcomas: a brief review. Med Oncol. 2015 Jan; 32(1):430. PMID: 25491143.
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    66. James AW, Chang L, Genshaft S, Dry SM. Coincident liposarcoma, carcinoid and gastrointestinal stromal tumor complicating type 1 neurofibromatosis: Case report and literature review. J Orthop. 2015 Oct; 12(Suppl 1):S111-6. PMID: 26719605.
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    67. Nguyen A, Scott MA, Dry SM, James AW. Roles of bone morphogenetic protein signaling in osteosarcoma. Int Orthop. 2014 Nov; 38(11):2313-22. PMID: 25209345.
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    68. Chung CG, James AW, Asatrian G, Chang L, Nguyen A, Le K, Bayani G, Lee R, Stoker D, Zhang X, Ting K, Péault B, Soo C. Human perivascular stem cell-based bone graft substitute induces rat spinal fusion. Stem Cells Transl Med. 2014 Oct; 3(10):1231-41. PMID: 25154782.
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    69. Velasco O, James AW, Asatrian G, Ajalat M, Pritchard T, Novshadian S, Murthy A, Bayani G, Zhang X, Ting K, Soo C. High resolution x-ray: a reliable approach for quantifying osteoporosis in a rodent model. Biores Open Access. 2014 Aug 01; 3(4):192-6. PMID: 25126483.
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    70. James AW, Shen J, Khadarian K, Pang S, Chung G, Goyal R, Asatrian G, Velasco O, Kim J, Zhang X, Ting K, Soo C. Lentiviral delivery of PPAR? shRNA alters the balance of osteogenesis and adipogenesis, improving bone microarchitecture. Tissue Eng Part A. 2014 Oct; 20(19-20):2699-710. PMID: 24785569.
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    71. Levi B, Péault B, James AW. Bone tissue engineering and regeneration. Biomed Res Int. 2014; 2014:137529. PMID: 25136553.
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    72. James AW, Nguyen A, Said J, Genshaft S, Lassman CR, Teitell M. Splenic hamartomas in Alagille syndrome: case report and literature review. Fetal Pediatr Pathol. 2014 Aug; 33(4):216-25. PMID: 24865822.
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    73. Levine BD, Seeger LL, James AW, Motamedi K. Subcutaneous panniculitis-like T-cell lymphoma: MRI features and literature review. Skeletal Radiol. 2014 Sep; 43(9):1307-11. PMID: 24719040.
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    74. Mravic M, Péault B, James AW. Current trends in bone tissue engineering. Biomed Res Int. 2014; 2014:865270. PMID: 24804256.
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    75. Mravic M, Asatrian G, Soo C, Lugassy C, Barnhill RL, Dry SM, Peault B, James AW. From pericytes to perivascular tumours: correlation between pathology, stem cell biology, and tissue engineering. Int Orthop. 2014 Sep; 38(9):1819-24. PMID: 24566993.
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    76. James AW, Tirado CA, Levine B, Dry SM. Abnormal karyotypes in osteochondroma: Case series and literature review. J Orthop. 2015 Jun; 12(2):70-4. PMID: 25972696.
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    77. James AW, Chang L, Levine B, Dry SM. Clavicular and meningeal alveolar soft part sarcoma: An unusual case and literature review. J Orthop. 2014 Mar; 11(1):48-53. PMID: 24719534.
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    78. James AW, Chang L, Shrestha S, Cochran A, Binder S, Tirado CA. Cytogenetics of melanoma: a review. J Assoc Genet Technol. 2014; 40(4):209-18. PMID: 26030295.
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    79. Asatrian G, Chang L, James AW. Muscle pouch implantation: an ectopic bone formation model. Methods Mol Biol. 2014; 1213:185-91. PMID: 25173383.
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    80. James AW. Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation. Scientifica (Cairo). 2013; 2013:684736. PMID: 24416618.
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    81. Murray IR, West CC, Hardy WR, James AW, Park TS, Nguyen A, Tawonsawatruk T, Lazzari L, Soo C, Péault B. Natural history of mesenchymal stem cells, from vessel walls to culture vessels. Cell Mol Life Sci. 2014 Apr; 71(8):1353-74. PMID: 24158496.
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    82. Deshpande S, James AW, Blough J, Donneys A, Wang SC, Cederna PS, Buchman SR, Levi B. Reconciling the effects of inflammatory cytokines on mesenchymal cell osteogenic differentiation. J Surg Res. 2013 Nov; 185(1):278-85. PMID: 23972621.
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    83. Shen J, James AW, Zara JN, Asatrian G, Khadarian K, Zhang JB, Ho S, Kim HJ, Ting K, Soo C. BMP2-induced inflammation can be suppressed by the osteoinductive growth factor NELL-1. Tissue Eng Part A. 2013 Nov; 19(21-22):2390-401. PMID: 23758588.
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    84. Yuan W, James AW, Asatrian G, Shen J, Zara JN, Tian HJ, Siu RK, Zhang X, Wang JC, Dong J. NELL-1 based demineralized bone graft promotes rat spine fusion as compared to commercially available BMP-2 product. J Orthop Sci. 2013 Jul; 18(4):646-57. PMID: 23686083.
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    85. Askarinam A, James AW, Zara JN, Goyal R, Corselli M, Pan A, Liang P, Chang L, Rackohn T, Stoker D, Zhang X, Ting K, Péault B, Soo C. Human perivascular stem cells show enhanced osteogenesis and vasculogenesis with Nel-like molecule I protein. Tissue Eng Part A. 2013 Jun; 19(11-12):1386-97. PMID: 23406369.
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    86. Pan A, Chang L, Nguyen A, James AW. A review of hedgehog signaling in cranial bone development. Front Physiol. 2013; 4:61. PMID: 23565096.
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    87. Kwak J, Zara JN, Chiang M, Ngo R, Shen J, James AW, Le KM, Moon C, Zhang X, Gou Z, Ting K, Soo C. NELL-1 injection maintains long-bone quantity and quality in an ovariectomy-induced osteoporotic senile rat model. Tissue Eng Part A. 2013 Feb; 19(3-4):426-36. PMID: 23083222.
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    88. Shen J, James AW, Chung J, Lee K, Zhang JB, Ho S, Lee KS, Kim TM, Niimi T, Kuroda S, Ting K, Soo C. NELL-1 promotes cell adhesion and differentiation via Integrinß1. J Cell Biochem. 2012 Dec; 113(12):3620-8. PMID: 22807400.
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    89. James AW, Zara JN, Corselli M, Askarinam A, Zhou AM, Hourfar A, Nguyen A, Megerdichian S, Asatrian G, Pang S, Stoker D, Zhang X, Wu B, Ting K, Péault B, Soo C. An abundant perivascular source of stem cells for bone tissue engineering. Stem Cells Transl Med. 2012 Sep; 1(9):673-84. PMID: 23197874.
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    123. Brugmann SA, Allen NC, James AW, Mekonnen Z, Madan E, Helms JA. A primary cilia-dependent etiology for midline facial disorders. Hum Mol Genet. 2010 Apr 15; 19(8):1577-92. PMID: 20106874.
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