Ana J Coito

Title(s)Professor-in-Residence, Surgery
SchoolMedicine
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    Matrix Metalloproteinases in Hepatic Ischemia and Reperfusion Injury
    NIH R56AI057832Apr 1, 2010 - May 27, 2010
    Role: Principal Investigator
    Matrix Metalloproteinases in Hepatic Ischemia and Reperfusion Injury
    NIH R01AI057832Jan 1, 2004 - Mar 31, 2016
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Functional crosstalk between myeloid Foxo1-β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response. Cell Death Differ. 2021 May; 28(5):1705-1719. Li C, Sheng M, Lin Y, Xu D, Tian Y, Zhan Y, Jiang L, Coito AJ, Busuttil RW, Farmer DG, Kupiec-Weglinski JW, Ke B. PMID: 33288903; PMCID: PMC8167164.
      View in: PubMed   Mentions: 1     Fields:    
    2. Tissue Inhibitor of Metalloproteinase 3 Deficiency Disrupts the Hepatocyte E-Cadherin/β-Catenin Complex and Induces Cell Death in Liver Ischemia/Reperfusion Injury. Liver Transpl. 2020 01; 26(1):113-126. Fujii T, Duarte S, Lee E, Ke B, Busuttil RW, Coito AJ. PMID: 31642174.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    3. Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury. Cell Mol Immunol. 2020 12; 17(12):1245-1256. Jin Y, Li C, Xu D, Zhu J, Wei S, Zhong A, Sheng M, Duarte S, Coito AJ, Busuttil RW, Xia Q, Kupiec-Weglinski JW, Ke B. PMID: 31673056; PMCID: PMC7784844.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    4. Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. Liver Transpl. 2019 02; 25(2):288-301. Kato H, Duarte S, Miller MG, Busuttil RW, Coito AJ. PMID: 30358115; PMCID: PMC6355355.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury. Am J Pathol. 2018 08; 188(8):1820-1832. Duarte S, Matian P, Ma S, Busuttil RW, Coito AJ. PMID: 29870740; PMCID: PMC6099362.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    6. Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice. PLoS One. 2015; 10(9):e0137642. Kato H, Duarte S, Liu D, Busuttil RW, Coito AJ. PMID: 26355684; PMCID: PMC4565667.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    7. Matrix metalloproteinases in liver injury, repair and fibrosis. Matrix Biol. 2015 May-Jul; 44-46:147-56. Duarte S, Baber J, Fujii T, Coito AJ. PMID: 25599939; PMCID: PMC4495728.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansCells
    8. Hepatic ischemia and reperfusion injury in the absence of myeloid cell-derived COX-2 in mice. PLoS One. 2014; 9(5):e96913. Duarte S, Kato H, Kuriyama N, Suko K, Ishikawa TO, Busuttil RW, Herschman HR, Coito AJ. PMID: 24819536; PMCID: PMC4018446.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    9. MMP-9 deficiency shelters endothelial PECAM-1 expression and enhances regeneration of steatotic livers after ischemia and reperfusion injury. J Hepatol. 2014 May; 60(5):1032-9. Kato H, Kuriyama N, Duarte S, Clavien PA, Busuttil RW, Coito AJ. PMID: 24412604; PMCID: PMC3995823.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    10. Fibronectin-α4β1 interactions in hepatic cold ischemia and reperfusion injury: regulation of MMP-9 and MT1-MMP via the p38 MAPK pathway. Am J Transplant. 2012 Oct; 12(10):2689-99. Duarte S, Shen XD, Fondevila C, Busuttil RW, Coito AJ. PMID: 22812390; PMCID: PMC3459169.
      View in: PubMed   Mentions:
    11. TIMP-1 deficiency leads to lethal partial hepatic ischemia and reperfusion injury. Hepatology. 2012 Sep; 56(3):1074-85. Duarte S, Hamada T, Kuriyama N, Busuttil RW, Coito AJ. PMID: 22407827; PMCID: PMC3386467.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    12. Regulated hepatic reperfusion mitigates ischemia-reperfusion injury and improves survival after prolonged liver warm ischemia: a pilot study on a novel concept of organ resuscitation in a large animal model. J Am Coll Surg. 2012 Apr; 214(4):505-15; discussion 515-6. Hong JC, Koroleff D, Xia V, Chang CM, Duarte SM, Xu J, Lassman C, Kupiec-Weglinski J, Coito AJ, Busuttil RW. PMID: 22321520.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    13. Tenascin-C: a novel mediator of hepatic ischemia and reperfusion injury. Hepatology. 2011 Dec; 54(6):2125-36. Kuriyama N, Duarte S, Hamada T, Busuttil RW, Coito AJ. PMID: 21898491; PMCID: PMC3230719.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    14. Leukocyte transmigration across endothelial and extracellular matrix protein barriers in liver ischemia/reperfusion injury. Curr Opin Organ Transplant. 2011 Feb; 16(1):34-40. Coito AJ. PMID: 21150609; PMCID: PMC3156893.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    15. Cytoprotective effects of a cyclic RGD peptide in steatotic liver cold ischemia and reperfusion injury. Am J Transplant. 2009 Oct; 9(10):2240-50. Fondevila C, Shen XD, Duarte S, Busuttil RW, Coito AJ. PMID: 19681824; PMCID: PMC2981149.
      View in: PubMed   Mentions:
    16. Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury. Am J Pathol. 2009 Jun; 174(6):2265-77. Hamada T, Duarte S, Tsuchihashi S, Busuttil RW, Coito AJ. PMID: 19443702; PMCID: PMC2684191.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    17. Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. J Immunol. 2008 Feb 01; 180(3):1843-53. Hamada T, Tsuchihashi S, Avanesyan A, Duarte S, Moore C, Busuttil RW, Coito AJ. PMID: 18209082; PMCID: PMC3589995.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    18. Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury. Hepatology. 2008 Jan; 47(1):186-98. Hamada T, Fondevila C, Busuttil RW, Coito AJ. PMID: 17880014.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    19. Fibronectin-alpha4beta1 integrin interactions regulate metalloproteinase-9 expression in steatotic liver ischemia and reperfusion injury. Am J Pathol. 2007 Feb; 170(2):567-77. Moore C, Shen XD, Gao F, Busuttil RW, Coito AJ. PMID: 17255325; PMCID: PMC1851880.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    20. Cyclic RGD peptides with high affinity for alpha5beta1 integrin protect genetically fat Zucker rat livers from cold ischemia/reperfusion injury. Transplant Proc. 2005 May; 37(4):1679-81. Fondevila C, Shen XD, Moore C, Busuttil RW, Coito AJ. PMID: 15919428.
      View in: PubMed   Mentions:
    21. Blockade of fibronectin-alpha4beta1 adhesive interactions down-regulates cyclooxygenase-2 inducible nitric oxide synthase and prolongs recipient survival in a 24-hour model of cold hepatic ischemia-reperfusion injury. Transplant Proc. 2005 May; 37(4):1682-3. Moore C, Shen XD, Fondevila C, Gao F, Coito AJ. PMID: 15919429.
      View in: PubMed   Mentions:
    22. Fibronectin-alpha4beta1 integrin interactions modulate p42/44 MAPK phosphorylation in steatotic liver cold ischemia-reperfusion injury. Transplant Proc. 2005 Jan-Feb; 37(1):432-4. Moore C, Shen XD, Fondevila C, Coito AJ. PMID: 15808667.
      View in: PubMed   Mentions:
    23. Fibronectin-alpha 4 beta 1 integrin-mediated blockade protects genetically fat Zucker rat livers from ischemia/reperfusion injury. Am J Pathol. 2003 Apr; 162(4):1229-39. Amersi F, Shen XD, Moore C, Melinek J, Busuttil RW, Kupiec-Weglinski JW, Coito AJ. PMID: 12651615; PMCID: PMC1851218.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    24. Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury. J Am Soc Nephrol. 2003 Mar; 14(3):745-54. Blydt-Hansen TD, Katori M, Lassman C, Ke B, Coito AJ, Iyer S, Buelow R, Ettenger R, Busuttil RW, Kupiec-Weglinski JW. PMID: 12595512.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    25. FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration. Am J Transplant. 2002 Oct; 2(9):843-9. Anselmo DM, Amersi FF, Shen XD, Gao F, Katori M, Lassman C, Ke B, Coito AJ, Ma J, Brinkmann V, Busuttil RW, Kupiec-Weglinski JW, Farmer DG. PMID: 12392290.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    26. The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation. J Immunol. 2002 Aug 01; 169(3):1270-6. Zhai Y, Shen XD, Gao F, Coito AJ, Wasowska BA, Salama A, Schmitt I, Busuttil RW, Sayegh MH, Kupiec-Weglinski JW. PMID: 12133948.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    27. CD62-PSGL-1 interactions regulate cytokine chemokine and apoptotic networks in cardiac allograft recipients. Transplant Proc. 2002 Aug; 34(5):1463-4. Coito AJ, Shaw GD, Meng L, Moore C, Ma J, Busuttil RW, Kupiec-Weglinski JW. PMID: 12176441.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. P-selectin glycoprotein ligand-1 (rPSGL-Ig)-mediated blockade of CD62 selectin molecules protects rat steatotic liver grafts from ischemia/reperfusion injury. Am J Transplant. 2002 Aug; 2(7):600-8. Amersi F, Farmer DG, Shaw GD, Kato H, Coito AJ, Kaldas F, Zhao D, Lassman CR, Melinek J, Ma J, Volk HD, Kupiec-Weglinski JW, Busuttil RW. PMID: 12201360.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    29. FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injury. Transplant Proc. 2002 Aug; 34(5):1467-8. Anselmo D, Amersi FF, Shen XD, Gao F, Katori M, Ke B, Lassman C, Coito AJ, Brinkmann V, Busuttil RW, Kupiec-Weglinski JW, Farmer DG. PMID: 12176443.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    30. Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury. Transplantation. 2002 Jul 15; 74(1):96-102. Coito AJ, Buelow R, Shen XD, Amersi F, Moore C, Volk HD, Busuttil RW, Kupiec-Weglinski JW. PMID: 12134106.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    31. A novel CD154 monoclonal antibody in acute and chronic rat vascularized cardiac allograft rejection. Transplantation. 2002 Jun 15; 73(11):1736-42. Yuan X, Dong VM, Coito AJ, Waaga AM, Salama AD, Benjamin CD, Sayegh MH, Chandraker A. PMID: 12084995.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Mechanisms of targeting CD28 by a signaling monoclonal antibody in acute and chronic allograft rejection. Transplantation. 2002 Apr 27; 73(8):1310-7. Dong VM, Yuan X, Coito AJ, Waaga AM, Sayegh MH, Chandraker A. PMID: 11981427.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    33. Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway. Transplantation. 2002 Jan 27; 73(2):287-92. Katori M, Buelow R, Ke B, Ma J, Coito AJ, Iyer S, Southard D, Busuttil RW, Kupiec-Weglinski JW. PMID: 11821745.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    34. Selectin-mediated interactions regulate cytokine networks and macrophage heme oxygenase-1 induction in cardiac allograft recipients. Lab Invest. 2002 Jan; 82(1):61-70. Coito AJ, Shaw GD, Li J, Ke B, Ma J, Busuttil RW, Kupiec-Weglinski JW. PMID: 11796826.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    35. Allochimeric class I MHC molecules prevent chronic rejection and attenuate alloantibody responses. Transplantation. 2001 Oct 27; 72(8):1408-16. Singer JS, Mhoyan A, Fishbein MC, Shen XD, Gao F, Zhao D, Coito AJ, Reemtsen BL, Amersi F, Busuttil RW, Kupiec-Weglinski JW, Ghobrial RM. PMID: 11685113.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    36. Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation. Am J Transplant. 2001 Jul; 1(2):121-8. Kato H, Amersi F, Buelow R, Melinek J, Coito AJ, Ke B, Busuttil RW, Kupiec-Weglinski JW. PMID: 12099359.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    37. Allochimeric class I MHC inhibits chronic rejection in cardiac allografts. Transplant Proc. 2001 Feb-Mar; 33(1-2):179. Singer JS, Shen X, Fishbein M, Mhoyan A, Zhao D, Reemsteen B, Gao F, Amersi F, Coito AJ, Busuttil RW, Weglinski JK, Ghobrial RM. PMID: 11266768.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    38. CD40 ligand-CD40 T cell costimulation pathway is required for host sensitization in the immune cascade leading to accelerated allograft rejection. Transplant Proc. 2001 Feb-Mar; 33(1-2):304-5. Kupiec-Weglinski JW, Shen XD, Gao F, Zhai Y, Coito AJ, Sayegh MH. PMID: 11266829.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    39. Chronic allograft rejection versus tolerance: a critical role for EIIIA(+) fibronectin. Transplant Proc. 2001 Feb-Mar; 33(1-2):526-7. Coito AJ, Kato H, Azimi R, Kupiec-Weglinski JW. PMID: 11266940.
      View in: PubMed   Mentions:
    40. Homing of in vitro-generated donor antigen-reactive CD4+ T lymphocytes to renal allografts is alpha 4 beta 1 but not alpha L beta 2 integrin dependent. J Immunol. 2001 Jan 01; 166(1):596-601. Hammer MH, Zhai Y, Katori M, Ritter T, Volk HD, Coito AJ, Kupiec-Weglinski JW. PMID: 11123342.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. Fibronectin-mononuclear cell interactions regulate type 1 helper T cell cytokine network in tolerant transplant recipients. Am J Pathol. 2000 Oct; 157(4):1207-18. Coito AJ, Onodera K, Kato H, Busuttil RW, Kupiec-Weglinski JW. PMID: 11021825; PMCID: PMC1850166.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    42. Extracellular matrix proteins in organ transplantation. Transplantation. 2000 Jun 27; 69(12):2465-73. Coito AJ, Kupiec-Weglinski JW. PMID: 10910263.
      View in: PubMed   Mentions:
    43. Renal allograft protection with losartan in Fisher-->Lewis rats: hemodynamics, macrophages, and cytokines. Kidney Int. 2000 Jun; 57(6):2618-25. Ziai F, Nagano H, Kusaka M, Coito AJ, Troy JL, Nadeau KC, Rennke HG, Tilney NL, Brenner BM, MacKenzie HS. PMID: 10844632.
      View in: PubMed   Mentions:
    44. Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic Bag-1 in parallel with enhanced Th2-type cytokine expression. Transplantation. 2000 Apr 27; 69(8):1690-4. Ke B, Coito AJ, Kato H, Zhai Y, Wang T, Sawitzki B, Seu P, Busuttil RW, Kupiec-Weglinski JW. PMID: 10836382.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    45. Fibronectin in immune responses in organ transplant recipients. Dev Immunol. 2000; 7(2-4):239-48. Coito AJ, de Sousa M, Kupiec-Weglinski JW. PMID: 11097215.
      View in: PubMed   Mentions:
    46. Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J Clin Invest. 1999 Dec; 104(11):1631-9. Amersi F, Buelow R, Kato H, Ke B, Coito AJ, Shen XD, Zhao D, Zaky J, Melinek J, Lassman CR, Kolls JK, Alam J, Ritter T, Volk HD, Farmer DG, Ghobrial RM, Busuttil RW, Kupiec-Weglinski JW. PMID: 10587527; PMCID: PMC409865.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    47. CD26/DPP IV-mediated modulation of acute rejection. Transplant Proc. 1999 Feb-Mar; 31(1-2):873. Korom S, De Meester I, Coito AJ, Graser E, Pratschke J, König S, Grimm H, Volk HD, Scharpé S, Kupiec-Weglinski JW. PMID: 10083382.
      View in: PubMed   Mentions:
    48. Blockade of alpha 4 beta 1-integrin-fibronectin adhesive interactions prevents chronic allograft rejection in sensitized recipients. Transplant Proc. 1998 Jun; 30(4):939-40. Coito AJ, Korom S, Hancock WW, Kupiec-Weglinski JW. PMID: 9636377.
      View in: PubMed   Mentions:
    49. Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients. II. Treatment with connecting segment-1 peptides prevents chronic rejection by attenuating arteriosclerotic development and suppressing intragraft T cell and macrophage activation. Transplantation. 1998 Mar 27; 65(6):854-9. Korom S, Hancock WW, Coito AJ, Kupiec-Weglinski JW. PMID: 9539099.
      View in: PubMed   Mentions:
    50. Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients: I. Treatment with connecting segment-1 peptides prevents acute rejection by suppressing intragraft mononuclear cell accumulation, endothelial activation, and cytokine expression. Transplantation. 1998 Mar 15; 65(5):699-706. Coito AJ, Korom S, Graser E, Volk HD, Van De Water L, Kupiec-Weglinski JW. PMID: 9521206.
      View in: PubMed   Mentions:
    51. Expression of fibronectin splicing variants in organ transplantation: a differential pattern between rat cardiac allografts and isografts. Am J Pathol. 1997 May; 150(5):1757-72. Coito AJ, Brown LF, Peters JH, Kupiec-Weglinski JW, van de Water L. PMID: 9137099.
      View in: PubMed   Mentions:
    52. Distinct fibronectin splicing variants: potential targets for therapeutic immunomodulation in organ allograft recipients. Transplant Proc. 1997 Feb-Mar; 29(1-2):1060-1. Coito AJ, Korom S, Van de Water L, Kupiec-Weglinski JW. PMID: 9123198.
      View in: PubMed   Mentions:
    53. Extracellular matrix proteins: bystanders or active participants in the allograft rejection cascade? Ann Transplant. 1996; 1(3):14-8. Coito AJ, Kupiec-Weglinski JW. PMID: 9869914.
      View in: PubMed   Mentions:
    54. Anti-TNF-alpha treatment down-regulates the expression of fibronectin and decreases cellular infiltration of cardiac allografts in rats. J Immunol. 1995 Mar 15; 154(6):2949-58. Coito AJ, Binder J, Brown LF, de Sousa M, Van de Water L, Kupiec-Weglinski JW. PMID: 7876561.
      View in: PubMed   Mentions:
    55. TNF-alpha upregulates the expression of fibronectin in acutely rejecting rat cardiac allografts. Transplant Proc. 1995 Feb; 27(1):463-5. Coito AJ, Binder J, Brown LF, de Sousa M, Van de Water L, Kupiec-Weglinski JW. PMID: 7879063.
      View in: PubMed   Mentions:
    56. The role of cellular and extracellular matrix adhesion proteins in organ transplantation. Cell Adhes Commun. 1994 Jul; 2(3):249-55. Coito AJ, De Sousa M, Kupiec-Weglinski JW. PMID: 7827962.
      View in: PubMed   Mentions:
    57. The expression of extracellular matrix proteins during accelerated rejection of cardiac allografts in sensitized rats. Transplantation. 1994 Feb 27; 57(4):599-605. Coito AJ, Binder J, de Sousa M, Kupiec-Weglinski JW. PMID: 8116048.
      View in: PubMed   Mentions:
    58. Adhesion molecule interaction with extracellular matrix. Exp Nephrol. 1993 Mar-Apr; 1(2):78-82. Kupiec-Weglinski JW, Heemann UW, Coito AJ, Tullius SG, Tilney NL, de Sousa M. PMID: 8081960.
      View in: PubMed   Mentions:
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