April Denise Thames

Title(s)Associate Professor-in-Residence, Psychiatry and Biobehavioral Sciences
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    The effects of lifetime stress on cognitive aging in the context of HIV-infection: Identifying sources of racial disparities
    NIH R01MH114761Aug 15, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Neurobehavioral and Functional Consequences of HIV in African Americans
    NIH K23MH095661May 1, 2012 - Dec 31, 2018
    Role: Principal Investigator

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    1. Socioeconomic Mobility and Psychological and Cognitive Functioning in a Diverse Sample of Adults With and Without HIV. Psychosom Med. 2021 Apr 01; 83(3):218-227. Weissberger GH, Núñez RA, Tureson K, Gold A, Thames AD. PMID: 33793453.
      View in: PubMed   Mentions:    Fields:    
    2. Creating an antiracist psychology by addressing professional complicity in psychological assessment. Psychol Assess. 2021 Mar; 33(3):279-285. Byrd DA, Rivera Mindt MM, Clark US, Clarke Y, Thames AD, Gammada EZ, Manly JJ. PMID: 33779204.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Suubi+Adherence-Round 2: A study protocol to examine the longitudinal HIV treatment adherence among youth living with HIV transitioning into young adulthood in Southern Uganda. BMC Public Health. 2021 01 21; 21(1):179. Ssewamala FM, Sensoy Bahar O, Nabunya P, Thames AD, Neilands TB, Damulira C, Mukasa B, Brathwaite R, Mellins C, Santelli J, Brown D, Guo S, Namatovu P, Kiyingi J, Namuwonge F, McKay MM. PMID: 33478469.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV. JAMA Netw Open. 2021 01 04; 4(1):e2031190. Nir TM, Fouche JP, Ananworanich J, Ances BM, Boban J, Brew BJ, Chaganti JR, Chang L, Ching CRK, Cysique LA, Ernst T, Faskowitz J, Gupta V, Harezlak J, Heaps-Woodruff JM, Hinkin CH, Hoare J, Joska JA, Kallianpur KJ, Kuhn T, Lam HY, Law M, Lebrun-Frénay C, Levine AJ, Mondot L, Nakamoto BK, Navia BA, Pennec X, Porges EC, Salminen LE, Shikuma CM, Surento W, Thames AD, Valcour V, Vassallo M, Woods AJ, Thompson PM, Cohen RA, Paul R, Stein DJ, Jahanshad N. PMID: 33449093.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. HIV, Vascular Risk Factors, and Cognition in the Combination Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis. J Int Neuropsychol Soc. 2021 04; 27(4):365-381. McIntosh EC, Tureson K, Rotblatt LJ, Singer EJ, Thames AD. PMID: 33161930.
      View in: PubMed   Mentions:    Fields:    
    6. Randomized, Placebo-Controlled Trial of Targeting Neuroinflammation with Ibudilast to Treat Methamphetamine Use Disorder. J Neuroimmune Pharmacol. 2020 06; 15(2):238-248. Heinzerling KG, Briones M, Thames AD, Hinkin CH, Zhu T, Wu YN, Shoptaw SJ. PMID: 31820289.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    7. Corrigendum to "Experienced discrimination and racial differences in leukocyte gene expression. [Psychoneuroendocrinology, 106 (2019), 277-283]". Psychoneuroendocrinology. 2019 Nov; 109:104422. Thames AD, Irwin MR, Breen EC, Cole SW. PMID: 31519314.
      View in: PubMed   Mentions:    Fields:    
    8. The joint effect of aging and HIV infection on microstructure of white matter bundles. Hum Brain Mapp. 2019 10 15; 40(15):4370-4380. Kuhn T, Jin Y, Huang C, Kim Y, Nir TM, Gullett JM, Jones JD, Sayegh P, Chung C, Dang BH, Singer EJ, Shattuck DW, Jahanshad N, Bookheimer SY, Hinkin CH, Zhu H, Thompson PM, Thames AD. PMID: 31271489.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Experienced discrimination and racial differences in leukocyte gene expression. Psychoneuroendocrinology. 2019 08; 106:277-283. Thames AD, Irwin MR, Breen EC, Cole SW. PMID: 31029930.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    10. Effects of trauma, economic hardship, and stress on neurocognition and everyday function in HIV. Health Psychol. 2019 Jan; 38(1):33-42. Watson CW, Sundermann EE, Hussain MA, Umlauf A, Thames AD, Moore RC, Letendre SL, Jeste DV, Morgan EE, Moore DJ. PMID: 30372103.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    11. Differential relationships between cannabis consumption and sleep health as a function of HIV status. Drug Alcohol Depend. 2018 11 01; 192:233-237. Lim AC, Thames AD. PMID: 30273891.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    12. Effects of Sleep Health on Cognitive Function in HIV+ and HIV- Adults. J Int Neuropsychol Soc. 2018 11; 24(10):1038-1046. Mahmood Z, Hammond A, Nunez RA, Irwin MR, Thames AD. PMID: 30165914.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Sexual Health Behavior and Mental Health Among Older African American Women: The Sistahs, Sexuality, and Mental Health Well-Being Project. J Womens Health (Larchmt). 2018 09; 27(9):1177-1185. Thames AD, Hammond A, Nunez RA, Mahmood Z, Jones F, Carter SL, Bilder RM, Fisher S, Bivens-Davis T, Jones L. PMID: 30070959.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. An augmented aging process in brain white matter in HIV. Hum Brain Mapp. 2018 06; 39(6):2532-2540. Kuhn T, Kaufmann T, Doan NT, Westlye LT, Jones J, Nunez RA, Bookheimer SY, Singer EJ, Hinkin CH, Thames AD. PMID: 29488278.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    15. Presumed structural and functional neural recovery after long-term abstinence from cocaine in male military veterans. Prog Neuropsychopharmacol Biol Psychiatry. 2018 06 08; 84(Pt A):18-29. He Q, Huang X, Turel O, Schulte M, Huang D, Thames A, Bechara A, Hser YI. PMID: 29410011.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Effects of social adversity and HIV on subcortical shape and neurocognitive function. Brain Imaging Behav. 2018 02; 12(1):96-108. Thames AD, Kuhn TP, Mahmood Z, Bilder RM, Williamson TJ, Singer EJ, Arentoft A. PMID: 28130744.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    17. Predictors of somatic symptom severity: The role of cumulative history of trauma and adversity in a diverse community sample. Psychol Trauma. 2018 Sep; 10(5):491-498. Loeb TB, Joseph NT, Wyatt GE, Zhang M, Chin D, Thames A, Aswad Y. PMID: 29154595.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Longitudinal intra-individual variability in neuropsychological performance relates to white matter changes in HIV. Neuropsychology. 2018 02; 32(2):206-212. Jones JD, Kuhn T, Mahmood Z, Singer EJ, Hinkin CH, Thames AD. PMID: 28891655.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Improvements in brain and behavior following eradication of hepatitis C. J Neurovirol. 2017 08; 23(4):593-602. Kuhn T, Sayegh P, Jones JD, Smith J, Sarma MK, Ragin A, Singer EJ, Albert Thomas M, Thames AD, Castellon SA, Hinkin CH. PMID: 28560632.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    20. Trauma and mental health in South Africa: Overview. Psychol Trauma. 2017 05; 9(3):249-251. Wyatt GE, Thames A, Simbayi L, Stein DJ, Burns J, Maselesele M. PMID: 28459266.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Differential relationships between social adversity and depressive symptoms by HIV status and racial/ethnic identity. Health Psychol. 2017 Feb; 36(2):133-142. Williamson TJ, Mahmood Z, Kuhn TP, Thames AD. PMID: 27929330.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Marijuana effects on changes in brain structure and cognitive function among HIV+ and HIV- adults. Drug Alcohol Depend. 2017 Jan 01; 170:120-127. Thames AD, Kuhn TP, Williamson TJ, Jones JD, Mahmood Z, Hammond A. PMID: 27889592.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    23. The effects of HIV and aging on subcortical shape alterations: A 3D morphometric study. Hum Brain Mapp. 2017 02; 38(2):1025-1037. Kuhn T, Schonfeld D, Sayegh P, Arentoft A, Jones JD, Hinkin CH, Bookheimer SY, Thames AD. PMID: 27778407.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    24. Psychosocial Correlates of Medication Adherence among HIV-Positive, Cognitively Impaired Individuals. J HIV AIDS Soc Serv. 2016; 15(4):404-416. Arentsen TJ, Panos S, Thames AD, Arbid JN, Castellon SA, Hinkin CH. PMID: 28713226.
      View in: PubMed   Mentions:
    25. HIV-transmission-related risk behavior in HIV+ African American men: Exploring biological, psychological, cognitive, and social factors. J HIV AIDS Soc Serv. 2016; 15(3):299-318. Arentoft A, Van Dyk K, Thames AD, Thaler NS, Sayegh P, Hinkin CH. PMID: 28713225.
      View in: PubMed   Mentions:
    26. Neurobehavioral Manifestations of Human Immunodeficiency Virus/AIDS: Diagnosis and Treatment. Neurol Clin. 2016 Feb; 34(1):33-53. Singer EJ, Thames AD. PMID: 26613994.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Combined effects of HIV and marijuana use on neurocognitive functioning and immune status. AIDS Care. 2016; 28(5):628-32. Thames AD, Mahmood Z, Burggren AC, Karimian A, Kuhn TP. PMID: 26694807.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    28. Electronic health record phenotyping improves detection and screening of type 2 diabetes in the general United States population: A cross-sectional, unselected, retrospective study. J Biomed Inform. 2016 Apr; 60:162-8. Anderson AE, Kerr WT, Thames A, Li T, Xiao J, Cohen MS. PMID: 26707455.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. Increased subcortical neural activity among HIV+ individuals during a lexical retrieval task. Neurobiol Dis. 2016 08; 92(Pt B):175-82. Thames AD, Sayegh P, Terashima K, Foley JM, Cho A, Arentoft A, Hinkin CH, Bookheimer SY. PMID: 26484382.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Comparing the unmatched count technique and direct self-report for sensitive health-risk behaviors in HIV+ adults. AIDS Care. 2016; 28(3):370-5. Arentoft A, Van Dyk K, Thames AD, Sayegh P, Thaler N, Schonfeld D, LaBrie J, Hinkin CH. PMID: 26856321.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. The role of chemokine C-C motif ligand 2 genotype and cerebrospinal fluid chemokine C-C motif ligand 2 in neurocognition among HIV-infected patients. AIDS. 2015 Jul 31; 29(12):1483-91. Thames AD, Briones MS, Magpantay LI, Martinez-Maza O, Singer EJ, Hinkin CH, Morgello S, Gelman BB, Moore DJ, Heizerling K, Levine AJ. PMID: 26244388.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    32. Increased neurocognitive intra-individual variability is associated with declines in medication adherence in HIV-infected adults. Neuropsychology. 2015 Nov; 29(6):919-925. Thaler NS, Sayegh P, Arentoft A, Thames AD, Castellon SA, Hinkin CH. PMID: 25730729.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    33. Ebola: translational science considerations. J Transl Med. 2015 Jan 16; 13:11. Chiappelli F, Bakhordarian A, Thames AD, Du AM, Jan AL, Nahcivan M, Nguyen MT, Sama N, Manfrini E, Piva F, Rocha RM, Maida CA. PMID: 25592846.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. Neuroimaging abnormalities, neurocognitive function, and fatigue in patients with hepatitis C. Neurol Neuroimmunol Neuroinflamm. 2015 Feb; 2(1):e59. Thames AD, Castellon SA, Singer EJ, Nagarajan R, Sarma MK, Smith J, Thaler NS, Truong JH, Schonfeld D, Thomas MA, Hinkin CH. PMID: 25610883.
      View in: PubMed   Mentions: 19     Fields:    
    35. Viral immune evasion in dengue: toward evidence-based revisions of clinical practice guidelines. Bioinformation. 2014; 10(12):726-33. Chiappelli F, Santos SM, Caldeira Brant XM, Bakhordarian A, Thames AD, Maida CA, Du AM, Jan AL, Nahcivan M, Nguyen MT, Sama N. PMID: 25670874.
      View in: PubMed   Mentions:
    36. Quality of education predicts performance on the Wide Range Achievement Test-4th Edition Word Reading subtest. Arch Clin Neuropsychol. 2014 Dec; 29(8):731-6. Sayegh P, Arentoft A, Thaler NS, Dean AC, Thames AD. PMID: 25404004.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    37. Mild test anxiety influences neurocognitive performance among African Americans and European Americans: identifying interfering and facilitating sources. Cultur Divers Ethnic Minor Psychol. 2015 Jan; 21(1):105-13. Thames AD, Panos SE, Arentoft A, Byrd DA, Hinkin CH, Arbid N. PMID: 25111554.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. Cannabis use and neurocognitive functioning in a non-clinical sample of users. Addict Behav. 2014 May; 39(5):994-9. Thames AD, Arbid N, Sayegh P. PMID: 24556155.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    39. A deconstruction of gambling task performance among HIV+ individuals: the differential contributions of problem solving and risk taking. J Clin Exp Neuropsychol. 2013; 35(10):1036-47. Arentoft A, Thames AD, Panos S, Patel S, Hinkin CH. PMID: 24168142.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity. Neurobehav HIV Med. 2013; 5:11-22. Panos SE, Hinkin CH, Singer EJ, Thames AD, Patel SM, Sinsheimer JS, Del Re AC, Gelman BB, Morgello S, Moore DJ, Levine AJ. PMID: 26617462.
      View in: PubMed   Mentions:
    41. The impact of neurobehavioral features on medication adherence in HIV: evidence from longitudinal models. AIDS Care. 2014 Jan; 26(1):79-86. Panos SE, Del Re AC, Thames AD, Arentsen TJ, Patel SM, Castellon SA, Singer EJ, Hinkin CH. PMID: 23756102.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    42. The aggregate effects of multiple comorbid risk factors on cognition among HIV-infected individuals. J Clin Exp Neuropsychol. 2013; 35(4):421-34. Patel SM, Thames AD, Arbid N, Panos SE, Castellon S, Hinkin CH. PMID: 23547924.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    43. Effects of stereotype threat, perceived discrimination, and examiner race on neuropsychological performance: simple as black and white? J Int Neuropsychol Soc. 2013 May; 19(5):583-93. Thames AD, Hinkin CH, Byrd DA, Bilder RM, Duff KJ, Mindt MR, Arentoft A, Streiff V. PMID: 23388089.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    44. Functional disability in medication management and driving among individuals with HIV: a 1-year follow-up study. J Clin Exp Neuropsychol. 2013; 35(1):49-58. Thames AD, Arentoft A, Rivera-Mindt M, Hinkin CH. PMID: 23237014.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    45. The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI. Brain Imaging Behav. 2012 Dec; 6(4):489-501. Skinner J, Carvalho JO, Potter GG, Thames A, Zelinski E, Crane PK, Gibbons LE, Alzheimer's Disease Neuroimaging Initiative . PMID: 22614326.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    46. Differential predictors of medication adherence in HIV: findings from a sample of African American and Caucasian HIV-positive drug-using adults. AIDS Patient Care STDS. 2012 Oct; 26(10):621-30. Thames AD, Moizel J, Panos SE, Patel SM, Byrd DA, Myers HF, Wyatt GE, Hinkin CH. PMID: 22889235.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    47. 2D MR Spectroscopy Combined with Prior-Knowledge Fitting Is Sensitive to HCV-Associated Cerebral Metabolic Abnormalities. Int J Hepatol. 2012; 2012:179365. Nagarajan R, Sarma MK, Thames AD, Castellon SA, Hinkin CH, Thomas MA. PMID: 22844602.
      View in: PubMed   Mentions:
    48. The role of HIV infection, cognition, and depression in risky decision-making. J Neuropsychiatry Clin Neurosci. 2012; 24(3):340-8. Thames AD, Streiff V, Patel SM, Panos SE, Castellon SA, Hinkin CH. PMID: 23037648.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    49. Basal ganglia structures differentially contribute to verbal fluency: evidence from Human Immunodeficiency Virus (HIV)-infected adults. Neuropsychologia. 2012 Feb; 50(3):390-5. Thames AD, Foley JM, Wright MJ, Panos SE, Ettenhofer M, Ramezani A, Streiff V, El-Saden S, Goodwin S, Bookheimer SY, Hinkin CH. PMID: 22223078.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    50. Longitudinal change in cognitive function and medication adherence in HIV-infected adults. AIDS Behav. 2011 Nov; 15(8):1888-94. Becker BW, Thames AD, Woo E, Castellon SA, Hinkin CH. PMID: 21437726.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    51. Depression, cognition, and self-appraisal of functional abilities in HIV: an examination of subjective appraisal versus objective performance. Clin Neuropsychol. 2011 Feb; 25(2):224-43. Thames AD, Becker BW, Marcotte TD, Hines LJ, Foley JM, Ramezani A, Singer EJ, Castellon SA, Heaton RK, Hinkin CH. PMID: 21331979.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    52. Medication and finance management among HIV-infected adults: the impact of age and cognition. J Clin Exp Neuropsychol. 2011 Feb; 33(2):200-9. Thames AD, Kim MS, Becker BW, Foley JM, Hines LJ, Singer EJ, Heaton RK, Castellon SA, Hinkin CH. PMID: 20694873.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    53. Disorganization and reality distortion in schizophrenia: a meta-analysis of the relationship between positive symptoms and neurocognitive deficits. Schizophr Res. 2010 Aug; 121(1-3):1-14. Ventura J, Thames AD, Wood RC, Guzik LH, Hellemann GS. PMID: 20579855.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    54. Neurocognitive functioning in HIV-1 infection: effects of cerebrovascular risk factors and age. Clin Neuropsychol. 2010 Feb; 24(2):265-85. Foley J, Ettenhofer M, Wright MJ, Siddiqi I, Choi M, Thames AD, Mason K, Castellon S, Hinkin CH. PMID: 20162495.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    55. Symptoms as mediators of the relationship between neurocognition and functional outcome in schizophrenia: a meta-analysis. Schizophr Res. 2009 Sep; 113(2-3):189-99. Ventura J, Hellemann GS, Thames AD, Koellner V, Nuechterlein KH. PMID: 19628375.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
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