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COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type. Arterioscler Thromb Vasc Biol. 2024 Oct 09.
Hilser JR, Spencer NJ, Afshari K, Gilliland FD, Hu H, Deb A, Lusis AJ, Wilson Tang WH, Hartiala JA, Hazen SL, Allayee H. PMID: 39381876.
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PubMed Mentions: Fields:
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Modulating the extracellular matrix to treat wound healing defects in Ehlers-Danlos syndrome. iScience. 2024 Sep 20; 27(9):110676.
Kelly-Scumpia KM, Archang MM, Purbey PK, Yokota T, Wu R, McCourt J, Li S, Crosbie RH, Scumpia PO, Deb A. PMID: 39262784; PMCID: PMC11389543.
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Serine protease inhibitor, SerpinA3n, regulates cardiac remodelling after myocardial infarction. Cardiovasc Res. 2024 Jul 02; 120(8):943-953.
Sun Q, Chen W, Wu R, Tao B, Wang P, Sun B, Alvarez JF, Ma F, Galindo DC, Maroney SP, Saviola AJ, Hansen KC, Li S, Deb A. PMID: 38666458.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems. bioRxiv. 2024 Jun 14.
Lin YJ, Tan XHM, Wang Y, Chung PS, Zhang X, Wu TH, Wu TY, Deb A, Chiou PY. PMID: 38915576; PMCID: PMC11195166.
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Massive field-of-view sub-cellular traction force videography enabled by Single-Pixel Optical Tracers (SPOT). Biosens Bioelectron. 2024 Aug 15; 258:116318.
Marvin Tan XH, Wang Y, Zhu X, Mendes FN, Chung PS, Chow YT, Man T, Lan H, Lin YJ, Zhang X, Zhang X, Nguyen T, Ardehali R, Teitell MA, Deb A, Chiou PY. PMID: 38701538.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Prognostic value of gut microbe-generated metabolite phenylacetylglutamine in patients with heart failure. Eur J Heart Fail. 2024 Feb; 26(2):233-241.
Tang WHW, Nemet I, Li XS, Wu Y, Haghikia A, Witkowski M, Koeth RA, Demuth I, König M, Steinhagen-Thiessen E, Bäckhed F, Fischbach MA, Deb A, Landmesser U, Hazen SL. PMID: 38124458.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Commun Biol. 2023 11 03; 6(1):1115.
Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. PMID: 37923961; PMCID: PMC10624922.
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PubMed Mentions: Translation:
AnimalsCells
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Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis. Science. 2023 09 29; 381(6665):1480-1487.
Wang Y, Li Q, Tao B, Angelini M, Ramadoss S, Sun B, Wang P, Krokhaleva Y, Ma F, Gu Y, Espinoza A, Yamauchi K, Pellegrini M, Novitch B, Olcese R, Qu Z, Song Z, Deb A. PMID: 37769108; PMCID: PMC10768850.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses. bioRxiv. 2023 Aug 05.
Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. PMID: 37577539; PMCID: PMC10418258.
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PubMed Mentions:
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Massively Concurrent Sub-Cellular Traction Force Videography enabled by Single-Pixel Optical Tracers (SPOTs). bioRxiv. 2023 Jul 26.
Marvin Tan XH, Wang Y, Zhu X, Mendes FN, Chung PS, Chow YT, Man T, Lan H, Lin YJ, Zhang X, Zhang X, Nguyen T, Ardehali R, Teitell MA, Deb A, Chiou PY. PMID: 37546726; PMCID: PMC10402113.
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PubMed Mentions:
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CPR: cardiac phosphatase in resuscitation. J Clin Invest. 2023 05 01; 133(9).
Deb A. PMID: 37115696; PMCID: PMC10145916.
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PubMed Mentions: Fields:
Translation:
Animals
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Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure. Circ Heart Fail. 2023 01; 16(1):e009972.
Romano KA, Nemet I, Prasad Saha P, Haghikia A, Li XS, Mohan ML, Lovano B, Castel L, Witkowski M, Buffa JA, Sun Y, Li L, Menge CM, Demuth I, König M, Steinhagen-Thiessen E, DiDonato JA, Deb A, Bäckhed F, Tang WHW, Naga Prasad SV, Landmesser U, Van Wagoner DR, Hazen SL. PMID: 36524472; PMCID: PMC9851997.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response. PLoS Biol. 2022 11; 20(11):e3001851.
Garcia G, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. PMID: 36346780; PMCID: PMC9642871.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells. Nat Commun. 2022 10 19; 13(1):6202.
Muthukrishnan SD, Kawaguchi R, Nair P, Prasad R, Qin Y, Johnson M, Wang Q, VanderVeer-Harris N, Pham A, Alvarado AG, Condro MC, Gao F, Gau R, Castro MG, Lowenstein PR, Deb A, Hinman JD, Pajonk F, Burns TC, Goldman SA, Geschwind DH, Kornblum HI. PMID: 36261421; PMCID: PMC9582000.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response. bioRxiv. 2022 Apr 08.
Garcia G, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V. PMID: 35441167; PMCID: PMC9016637.
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PubMed Mentions:
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Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair. J Clin Invest. 2022 01 18; 132(2).
Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. PMID: 34813507; PMCID: PMC8759793.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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PLucKing at Vascular Fibrosis. JACC Basic Transl Sci. 2021 Mar; 6(3):284-286.
Deb A. PMID: 33779665; PMCID: PMC7987588.
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Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection. J Lipid Res. 2021; 62:100061.
Hilser JR, Han Y, Biswas S, Gukasyan J, Cai Z, Zhu R, Tang WHW, Deb A, Lusis AJ, Hartiala JA, Allayee H. PMID: 33667465; PMCID: PMC7923911.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity. JCI Insight. 2021 01 25; 6(2).
Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. PMID: 33284134; PMCID: PMC7934846.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight. 2020 12 17; 5(24).
Wu R, Ma F, Tosevska A, Farrell C, Pellegrini M, Deb A. PMID: 33180747; PMCID: PMC7819745.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell. 2020 08 06; 182(3):545-562.e23.
Yokota T, McCourt J, Ma F, Ren S, Li S, Kim TH, Kurmangaliyev YZ, Nasiri R, Ahadian S, Nguyen T, Tan XHM, Zhou Y, Wu R, Rodriguez A, Cohn W, Wang Y, Whitelegge J, Ryazantsev S, Khademhosseini A, Teitell MA, Chiou PY, Birk DE, Rowat AC, Crosbie RH, Pellegrini M, Seldin M, Lusis AJ, Deb A. PMID: 32621799; PMCID: PMC7415659.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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DDR2, a discoidin domain receptor, is a marker of periosteal osteoblast and osteoblast progenitors. J Bone Miner Metab. 2020 Sep; 38(5):670-677.
Yang H, Sun L, Cai W, Gu J, Xu D, Deb A, Duan J. PMID: 32415375; PMCID: PMC7581459.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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How Stem Cells Turn into Bone and Fat. N Engl J Med. 2019 06 06; 380(23):2268-2270.
Deb A. PMID: 31167059; PMCID: PMC6901025.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Enhancement of β-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing NaV1.5 expression in mice. Heart Rhythm. 2019 11; 16(11):1720-1728.
Huo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu H. PMID: 31125668; PMCID: PMC7027965.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Endocardially Derived Macrophages Are Essential for Valvular Remodeling. Dev Cell. 2019 03 11; 48(5):617-630.e3.
Shigeta A, Huang V, Zuo J, Besada R, Nakashima Y, Lu Y, Ding Y, Pellegrini M, Kulkarni RP, Hsiai T, Deb A, Zhou B, Nakano H, Nakano A. PMID: 30799229; PMCID: PMC6440481.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans. G3 (Bethesda). 2018 11 06; 8(11):3499-3506.
Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. PMID: 30201759; PMCID: PMC6222577.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity. Circ Res. 2018 06 22; 123(1):73-85.
Yu J, Seldin MM, Fu K, Li S, Lam L, Wang P, Wang Y, Huang D, Nguyen TL, Wei B, Kulkarni RP, Di Carlo D, Teitell M, Pellegrini M, Lusis AJ, Deb A. PMID: 29691232; PMCID: PMC6014922.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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WNT Signaling in Cardiac and Vascular Disease. Pharmacol Rev. 2018 01; 70(1):68-141.
Foulquier S, Daskalopoulos EP, Lluri G, Hermans KCM, Deb A, Blankesteijn WM. PMID: 29247129; PMCID: PMC6040091.
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PubMed Mentions:
152 Fields:
Translation:
HumansAnimalsCells
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Prognostic Significance of Left Ventricular Fibrosis in Patients With Congenital Bicuspid Aortic Valve. Am J Cardiol. 2017 Oct 01; 120(7):1176-1179.
Lluri G, Renella P, Finn JP, Vorobiof G, Aboulhosn J, Deb A. PMID: 28802508; PMCID: PMC5593788.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Exogenous miR-29B Delivery Through a Hyaluronan-Based Injectable System Yields Functional Maintenance of the Infarcted Myocardium. Tissue Eng Part A. 2018 01; 24(1-2):57-67.
Monaghan MG, Holeiter M, Brauchle E, Layland SL, Lu Y, Deb A, Pandit A, Nsair A, Schenke-Layland K. PMID: 28463641; PMCID: PMC5770094.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. Am J Physiol Heart Circ Physiol. 2017 Apr 01; 312(4):H728-H741.
Seldin MM, Kim ED, Romay MC, Li S, Rau CD, Wang JJ, Krishnan KC, Wang Y, Deb A, Lusis AJ. PMID: 28235788; PMCID: PMC5407157.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell Stem Cell. 2017 02 02; 20(2):218-232.e5.
Pillai ICL, Li S, Romay M, Lam L, Lu Y, Huang J, Dillard N, Zemanova M, Rubbi L, Wang Y, Lee J, Xia M, Liang O, Xie YH, Pellegrini M, Lusis AJ, Deb A. PMID: 27867037; PMCID: PMC5291784.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med. 2016 10; 22(10):1131-1139.
Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. PMID: 27618650; PMCID: PMC5053883.
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PubMed Mentions:
200 Fields:
Translation:
HumansAnimalsCells
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Skeletal and cardiac muscle pericytes: Functions and therapeutic potential. Pharmacol Ther. 2017 03; 171:65-74.
Murray IR, Baily JE, Chen WCW, Dar A, Gonzalez ZN, Jensen AR, Petrigliano FA, Deb A, Henderson NC. PMID: 27595928; PMCID: PMC5726267.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Astrocytes Can Adopt Endothelial Cell Fates in a p53-Dependent Manner. Mol Neurobiol. 2017 08; 54(6):4584-4596.
Brumm AJ, Nunez S, Doroudchi MM, Kawaguchi R, Duan J, Pellegrini M, Lam L, Carmichael ST, Deb A, Hinman JD. PMID: 27389775; PMCID: PMC5219956.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation. 2015 Apr 28; 131(17):1468-70.
Deb A, Wang Y. PMID: 25820337; PMCID: PMC4539559.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature. 2014 Oct 30; 514(7524):585-90.
Ubil E, Duan J, Pillai IC, Rosa-Garrido M, Wu Y, Bargiacchi F, Lu Y, Stanbouly S, Huang J, Rojas M, Vondriska TM, Stefani E, Deb A. PMID: 25317562; PMCID: PMC4214889.
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PubMed Mentions:
189 Fields:
Translation:
AnimalsCells
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Cardiac fibroblast in development and wound healing. J Mol Cell Cardiol. 2014 May; 70:47-55.
Deb A, Ubil E. PMID: 24625635; PMCID: PMC4028446.
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PubMed Mentions:
79 Fields:
Translation:
HumansCells
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Cell-cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury. Cardiovasc Res. 2014 May 01; 102(2):214-23.
Deb A. PMID: 24591151; PMCID: PMC3989450.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J. 2012 Jan 18; 31(2):429-42.
Duan J, Gherghe C, Liu D, Hamlett E, Srikantha L, Rodgers L, Regan JN, Rojas M, Willis M, Leask A, Majesky M, Deb A. PMID: 22085926; PMCID: PMC3261567.
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PubMed Mentions:
178 Fields:
Translation:
AnimalsCells
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Wnt1 is a proangiogenic molecule, enhances human endothelial progenitor function, and increases blood flow to ischemic limbs in a HGF-dependent manner. FASEB J. 2011 Jun; 25(6):1836-43.
Gherghe CM, Duan J, Gong J, Rojas M, Klauber-Demore N, Majesky M, Deb A. PMID: 21321190; PMCID: PMC3219217.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium. Circ Res. 2010 Jun 11; 106(11):1753-62.
Huang J, Zhang Z, Guo J, Ni A, Deb A, Zhang L, Mirotsou M, Pratt RE, Dzau VJ. PMID: 20378860; PMCID: PMC2884066.
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PubMed Mentions:
118 Fields:
Translation:
HumansAnimalsCells
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Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise. Circulation. 2010 Feb 23; 121(7):850-2.
Deb A, Patterson C. PMID: 20142453; PMCID: PMC4084608.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. J Mol Cell Cardiol. 2009 Mar; 46(3):370-7.
Zhang Z, Deb A, Zhang Z, Pachori A, He W, Guo J, Pratt R, Dzau VJ. PMID: 19109969; PMCID: PMC2710029.
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PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
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SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. Stem Cells. 2008 Jan; 26(1):35-44.
Deb A, Davis BH, Guo J, Ni A, Huang J, Zhang Z, Mu H, Dzau VJ. PMID: 17916803; PMCID: PMC3045733.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair. Proc Natl Acad Sci U S A. 2007 Jan 30; 104(5):1643-8.
Mirotsou M, Zhang Z, Deb A, Zhang L, Gnecchi M, Noiseux N, Mu H, Pachori A, Dzau V. PMID: 17251350; PMCID: PMC1785280.
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PubMed Mentions:
257 Fields:
Translation:
AnimalsCells
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Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol Ther. 2006 Dec; 14(6):840-50.
Noiseux N, Gnecchi M, Lopez-Ilasaca M, Zhang L, Solomon SD, Deb A, Dzau VJ, Pratt RE. PMID: 16965940.
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PubMed Mentions:
194 Fields:
Translation:
AnimalsCells
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Images in cardiovascular medicine. Systemic complications of infective endocarditis. Circulation. 2005 Nov 15; 112(20):e324.
Friday BB, Deb A. PMID: 16286596.
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PubMed Mentions: Fields:
Translation:
Humans
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Bone marrow-derived myofibroblasts are present in adult human heart valves. J Heart Valve Dis. 2005 Sep; 14(5):674-8.
Deb A, Wang SH, Skelding K, Miller D, Simper D, Caplice N. PMID: 16245507.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Leptin receptor and functional effects of leptin in human endothelial progenitor cells. Atherosclerosis. 2005 Nov; 183(1):131-9.
Wolk R, Deb A, Caplice NM, Somers VK. PMID: 15950978.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Myocardial-cell replacement: the science, the clinic and the future. Nat Clin Pract Cardiovasc Med. 2004 Dec; 1(2):90-5.
Caplice NM, Deb A. PMID: 16265312.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Integrin profile and in vivo homing of human smooth muscle progenitor cells. Circulation. 2004 Oct 26; 110(17):2673-7.
Deb A, Skelding KA, Wang S, Reeder M, Simper D, Caplice NM. PMID: 15313945.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Lipoprotein(a): new insights into mechanisms of atherogenesis and thrombosis. Clin Cardiol. 2004 May; 27(5):258-64.
Deb A, Caplice NM. PMID: 15188938; PMCID: PMC6654090.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Images in clinical medicine. Systemic mastocytosis. N Engl J Med. 2003 Aug 14; 349(7):e7.
Deb A, Tefferi A. PMID: 12917319.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis. Circulation. 2003 Jul 15; 108(2):143-9.
Simper D, Wang S, Deb A, Holmes D, McGregor C, Frantz R, Kushwaha SS, Caplice NM. PMID: 12835206.
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PubMed Mentions:
29 Fields:
Translation:
HumansCellsCTClinical Trials
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Bone marrow-derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients. Circulation. 2003 Mar 11; 107(9):1247-9.
Deb A, Wang S, Skelding KA, Miller D, Simper D, Caplice NM. PMID: 12628942.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansCells