Loading...

Dasgupta, Asim

Title(s)Professor, Mimg
Phone3102068649
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    The role of hepatitis C virus 5'untranslated region in virus morphogenesis
    NIH/NIAID R21AI084090May 1, 2010 - Apr 30, 2013
    Role: Principal Investigator
    Towards Developing type 1a HCV cell culture model
    NIH/NIAID R21AI072180Jul 1, 2007 - Jun 30, 2010
    Role: Principal Investigator
    TRANSLATION INHIBITORS OF HEPATITIS C VIRUS
    NIH/NIAID R41AI045188Sep 30, 1999 - Sep 29, 2000
    Role: Principal Investigator
    TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    NIH/NIAID R01AI045733Sep 1, 1999 - Jun 30, 2005
    Role: Principal Investigator
    PICORNAVIRUS TRANSLATION/INHIBITION BY SMALL YEAST RNA
    NIH/NIAID U01AI038056Jul 1, 1995 - Jun 30, 1999
    Role: Principal Investigator
    INHIBITION OF HOST CELL TRANSCRIPTION BY POLIOVIRUS
    NIH/NIAID R01AI027451Feb 1, 1989 - Jan 31, 2005
    Role: Principal Investigator
    IN VITRO REPLICATION OF POLIOVIRUS
    NIH/NIAID R01AI018272Sep 30, 1981 - Mar 31, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. HSP70 Copurifies with Zika Virus Particles. Virology. 2018 09; 522:228-233. PMID: 30053656.
      View in: PubMed
    2. Lu NT, Liu NM, Patel D, Vu JQ, Liu L, Kim CY, Cho P, Khachatoorian R, Patel N, Magyar CE, Ganapathy E, Arumugaswami V, Dasgupta A, French SW. Oncoprotein Stathmin Modulates Sensitivity to Apoptosis in Hepatocellular Carcinoma Cells During Hepatitis C Viral Replication. J Cell Death. 2018; 11:1179066018785141. PMID: 30034249.
      View in: PubMed
    3. Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. Int J Antimicrob Agents. 2016 Apr; 47(4):289-96. PMID: 27013001.
      View in: PubMed
    4. Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 Jan 15; 475:46-55. PMID: 25462345.
      View in: PubMed
    5. Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 Apr; 454-455:118-27. PMID: 24725938.
      View in: PubMed
    6. Khachatoorian R, Arumugaswami V, Raychaudhuri S, Yeh GK, Maloney EM, Wang J, Dasgupta A, French SW. Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle. Virology. 2012 Nov 25; 433(2):346-55. PMID: 22975673.
      View in: PubMed
    7. Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW. A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production. Hepatology. 2012 Jun; 55(6):1662-72. PMID: 22183951.
      View in: PubMed
    8. Morizono K, Xie Y, Olafsen T, Lee B, Dasgupta A, Wu AM, Chen IS. The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry. Cell Host Microbe. 2011 Apr 21; 9(4):286-98. PMID: 21501828.
      View in: PubMed
    9. Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3157-62. PMID: 20133606.
      View in: PubMed
    10. Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW. The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology. 2009 Dec; 50(6):1756-64. PMID: 19839005.
      View in: PubMed
    11. Fontanes V, Raychaudhuri S, Dasgupta A. A cell-permeable peptide inhibits hepatitis C virus replication by sequestering IRES transacting factors. Virology. 2009 Nov 10; 394(1):82-90. PMID: 19740508.
      View in: PubMed
    12. Raychaudhuri S, Fontanes V, Barat B, Dasgupta A. Activation of ribosomal RNA transcription by hepatitis C virus involves upstream binding factor phosphorylation via induction of cyclin D1. Cancer Res. 2009 Mar 01; 69(5):2057-64. PMID: 19223538.
      View in: PubMed
    13. Arumugaswami V, Remenyi R, Kanagavel V, Sue EY, Ngoc Ho T, Liu C, Fontanes V, Dasgupta A, Sun R. High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog. 2008 Oct; 4(10):e1000182. PMID: 18927624.
      View in: PubMed
    14. Kundu P, Raychaudhuri S, Tsai W, Dasgupta A. Shutoff of RNA polymerase II transcription by poliovirus involves 3C protease-mediated cleavage of the TATA-binding protein at an alternative site: incomplete shutoff of transcription interferes with efficient viral replication. J Virol. 2005 Aug; 79(15):9702-13. PMID: 16014932.
      View in: PubMed
    15. Jhaveri R, Kundu P, Shapiro AM, Venkatesan A, Dasgupta A. Effect of heptitis C virus core protein on cellular gene expression: specific inhibition of cyclooxygenase 2. J Infect Dis. 2005 May 01; 191(9):1498-506. PMID: 15809909.
      View in: PubMed
    16. Banerjee R, Weidman MK, Echeverri A, Kundu P, Dasgupta A. Regulation of poliovirus 3C protease by the 2C polypeptide. J Virol. 2004 Sep; 78(17):9243-56. PMID: 15308719.
      View in: PubMed
    17. Dasgupta A, Das S, Izumi R, Venkatesan A, Barat B. Targeting internal ribosome entry site (IRES)-mediated translation to block hepatitis C and other RNA viruses. FEMS Microbiol Lett. 2004 May 15; 234(2):189-99. PMID: 15135522.
      View in: PubMed
    18. Izumi RE, Das S, Barat B, Raychaudhuri S, Dasgupta A. A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation. J Virol. 2004 Apr; 78(7):3763-76. PMID: 15016896.
      View in: PubMed
    19. Sharma R, Raychaudhuri S, Dasgupta A. Nuclear entry of poliovirus protease-polymerase precursor 3CD: implications for host cell transcription shut-off. Virology. 2004 Mar 15; 320(2):195-205. PMID: 15016543.
      View in: PubMed
    20. Dasgupta A. Targeting TFIIH to inhibit host cell transcription by Rift Valley Fever Virus. Mol Cell. 2004 Feb 27; 13(4):456-8. PMID: 14992716.
      View in: PubMed
    21. Weidman MK, Sharma R, Raychaudhuri S, Kundu P, Tsai W, Dasgupta A. The interaction of cytoplasmic RNA viruses with the nucleus. Virus Res. 2003 Sep; 95(1-2):75-85. PMID: 12921997.
      View in: PubMed
    22. Venkatesan A, Sharma R, Dasgupta A. Cell cycle regulation of hepatitis C and encephalomyocarditis virus internal ribosome entry site-mediated translation in human embryonic kidney 293 cells. Virus Res. 2003 Aug; 94(2):85-95. PMID: 12902037.
      View in: PubMed
    23. Banerjee R, Dasgupta A. Interaction of picornavirus 2C polypeptide with the viral negative-strand RNA. J Gen Virol. 2001 Nov; 82(Pt 11):2621-2627. PMID: 11602773.
      View in: PubMed