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David Wayne Dawson

Title(s)Associate Professor-in-Residence, Pathology and Laboratory Medicine
SchoolMedicine
Address760 Westwood Plaza A3-251
Los Angeles CA 90024
Phone72799
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    UCLA-Caltech Medical Scientist Training Program
    NIH/NIGMS T32GM008042Jul 1, 1983 - Jun 30, 2024
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Investigating PSMA-Targeted Radioligand Therapy Efficacy as a Function of Cellular PSMA Levels and Intratumoral PSMA Heterogeneity. Clin Cancer Res. 2020 Jun 15; 26(12):2946-2955. Current K, Meyer C, Magyar CE, Mona CE, Almajano J, Slavik R, Stuparu AD, Cheng C, Dawson DW, Radu CG, Czernin J, Lueckerath K. PMID: 31932492.
      View in: PubMed   Mentions:    Fields:    
    2. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2019 07; 68(7):1271-1286. Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernández-Zapico ME, Iliopoulos D. PMID: 30337373.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    3. Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model. Sci Rep. 2018 04 12; 8(1):5899. Chang HH, Moro A, Chou CEN, Dawson DW, French S, Schmidt AI, Sinnett-Smith J, Hao F, Hines OJ, Eibl G, Rozengurt E. PMID: 29651002.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    4. Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice. PLoS One. 2017; 12(9):e0184455. Chang HH, Moro A, Takakura K, Su HY, Mo A, Nakanishi M, Waldron RT, French SW, Dawson DW, Hines OJ, Li G, Go VLW, Sinnett-Smith J, Pandol SJ, Lugea A, Gukovskaya AS, Duff MO, Rosenberg DW, Rozengurt E, Eibl G. PMID: 28886117.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    5. Preoperative Treatment With FOLFIRINOX and Successful Resection for a Patient With Mixed Acinar-Endocrine Carcinoma of the Pancreas. Pancreas. 2017 Apr; 46(4):e32-e34. Sugimoto M, Hines OJ, Dawson DW, Muthusamy VR, Reber HA, Donahue TR. PMID: 28291165.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget. 2017 Mar 21; 8(12):19074-19088. Nguyen AH, Elliott IA, Wu N, Matsumura C, Vogelauer M, Attar N, Dann A, Ghukasyan R, Toste PA, Patel SG, Williams JL, Li L, Dawson DW, Radu C, Kurdistani SK, Donahue TR. PMID: 27894105.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    7. Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism. Surgery. 2017 06; 161(6):1570-1578. Schmidt A, Sinnett-Smith J, Young S, Chang HH, Hines OJ, Dawson DW, Rozengurt E, Eibl G. PMID: 28222855.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Assessment of a Revised Management Strategy for Patients With Intraductal Papillary Mucinous Neoplasms Involving the Main Pancreatic Duct. JAMA Surg. 2017 01 18; 152(1):e163349. Sugimoto M, Elliott IA, Nguyen AH, Kim S, Muthusamy VR, Watson R, Hines OJ, Dawson DW, Reber HA, Donahue TR. PMID: 27829085.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Association of Histopathologic Phenotype of Periampullary Adenocarcinomas With Survival. JAMA Surg. 2017 01 01; 152(1):82-88. Williams JL, Chan CK, Toste PA, Elliott IA, Vasquez CR, Sunjaya DB, Swanson EA, Koo J, Hines OJ, Reber HA, Dawson DW, Donahue TR. PMID: 27732711.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    10. Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study. Pancreas. 2016 10; 45(9):1353-8. Moris M, Dawson DW, Jiang J, Lewis J, Nassar A, Takeuchi KK, Lay AR, Zhai Q, Donahue TR, Kelly KA, Crawford HC, Wallace M. PMID: 27101571.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Allograft biopsy findings in patients with small bowel transplantation. Clin Transplant. 2016 11; 30(11):1433-1439. Koo J, Dawson DW, Dry S, French SW, Naini BV, Wang HL. PMID: 27582272.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality. Trends Endocrinol Metab. 2016 11; 27(11):770-781. Donahue TR, Dawson DW. PMID: 27461042.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence. Gastroenterology. 2016 08; 151(2):234-7. Dawson DW, Fernandez-Zapico ME. PMID: 27374366.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Mol Cancer Res. 2016 05; 14(5):437-47. Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. PMID: 26979711.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    15. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 Mar; 45(3):458-65. Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. PMID: 26495779.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    16. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 06; 159(6):1520-1527. Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. PMID: 26847803.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Mol Cancer Res. 2015 Nov; 13(11):1509-19. Arensman MD, Nguyen P, Kershaw KM, Lay AR, Ostertag-Hill CA, Sherman MH, Downes M, Liddle C, Evans RM, Dawson DW. PMID: 26224368.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    18. p85a is a microRNA target and affects chemosensitivity in pancreatic cancer. J Surg Res. 2015 Jun 15; 196(2):285-293. Toste PA, Li L, Kadera BE, Nguyen AH, Tran LM, Wu N, Madnick DL, Patel SG, Dawson DW, Donahue TR. PMID: 25846727.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    19. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clin Cancer Res. 2015 Jan 01; 21(1):157-65. Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. PMID: 25348515.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    20. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. . 2014 Oct; 13(10):2303-14. Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. PMID: 25082960.
      View in: PubMed   Mentions:
    21. Locally advanced pancreatic cancer: association between prolonged preoperative treatment and lymph-node negativity and overall survival. JAMA Surg. 2014 Feb; 149(2):145-53. Kadera BE, Sunjaya DB, Isacoff WH, Li L, Hines OJ, Tomlinson JS, Dawson DW, Rochefort MM, Donald GW, Clerkin BM, Reber HA, Donahue TR. PMID: 24306217.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Nonfunctional pancreatic neuroendocrine tumors <2 cm on preoperative imaging are associated with a low incidence of nodal metastasis and an excellent overall survival. J Gastrointest Surg. 2013 Dec; 17(12):2105-13. Toste PA, Kadera BE, Tatishchev SF, Dawson DW, Clerkin BM, Muthusamy R, Watson R, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. PMID: 24101447.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    23. Response to comments on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604. Diabetes. 2013 Oct; 62(10):e19-22. Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. PMID: 24065800.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    24. MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. PLoS One. 2013; 8(8):e71978. Kadera BE, Li L, Toste PA, Wu N, Adams C, Dawson DW, Donahue TR. PMID: 23991015.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    25. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer Prev Res (Phila). 2013 Oct; 6(10):1064-73. Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. PMID: 23943783.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    26. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes. 2013 Jul; 62(7):2595-604. Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. PMID: 23524641.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    27. HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer. 2013 Feb 01; 119(3):529-39. Nguyen Kovochich A, Arensman M, Lay AR, Rao NP, Donahue T, Li X, French SW, Dawson DW. PMID: 22914903.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    28. Integrative survival-based molecular profiling of human pancreatic cancer. Clin Cancer Res. 2012 Mar 01; 18(5):1352-63. Donahue TR, Tran LM, Hill R, Li Y, Kovochich A, Calvopina JH, Patel SG, Wu N, Hindoyan A, Farrell JJ, Li X, Dawson DW, Wu H. PMID: 22261810.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    29. Dysregulation of Wnt/ß-catenin signaling in gastrointestinal cancers. Gastroenterology. 2012 Feb; 142(2):219-32. White BD, Chien AJ, Dawson DW. PMID: 22155636.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansCells
    30. Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy. Cell Stem Cell. 2011 Nov 04; 9(5):383-4. Donahue TR, Dawson DW. PMID: 22056131.
      View in: PubMed   Mentions: 2     Fields:    
    31. Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells. Pancreas. 2011 Apr; 40(3):453-9. Takahashi H, Li A, Dawson DW, Hines OJ, Reber HA, Eibl G. PMID: 21343834.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    32. Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer. Am J Pathol. 2011 Mar; 178(3):1340-9. Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ. PMID: 21356384.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    33. N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Surgery. 2011 May; 149(5):614-24. Angst E, Dawson DW, Stroka D, Gloor B, Park J, Candinas D, Reber HA, Hines OJ, Eibl G. PMID: 21236457.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    34. PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Res. 2010 Sep 15; 70(18):7114-24. Hill R, Calvopina JH, Kim C, Wang Y, Dawson DW, Donahue TR, Dry S, Wu H. PMID: 20807812.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    35. Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. Pancreas. 2010 Jul; 39(5):675-9. Angst E, Dawson DW, Nguyen A, Park J, Go VL, Reber HA, Hines OJ, Eibl G. PMID: 20173668.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    36. Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts. J Agric Food Chem. 2010 Jun 23; 58(12):7252-7. Zhang L, Angst E, Park JL, Moro A, Dawson DW, Reber HA, Eibl G, Hines OJ, Go VL, Lu QY. PMID: 20499918.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    37. Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. Pancreas. 2010 Apr; 39(3):332-9. Pham H, Chen M, Li A, King J, Angst E, Dawson DW, Park J, Reber HA, Hines OJ, Eibl G. PMID: 19820419.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    38. Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. J Clin Oncol. 2010 Mar 10; 28(8):1358-65. Manuyakorn A, Paulus R, Farrell J, Dawson NA, Tze S, Cheung-Lau G, Hines OJ, Reber H, Seligson DB, Horvath S, Kurdistani SK, Guha C, Dawson DW. PMID: 20142597.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    39. Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress. Am J Pathol. 2009 Oct; 175(4):1653-61. Balatoni CE, Dawson DW, Suh J, Sherman MH, Sanders G, Hong JS, Frank MJ, Malone CS, Said JW, Teitell MA. PMID: 19717643.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    40. Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. Blood. 2009 Mar 12; 113(11):2478-87. Frank MJ, Dawson DW, Bensinger SJ, Hong JS, Knosp WM, Xu L, Balatoni CE, Allen EL, Shen RR, Bar-Sagi D, Martin GR, Teitell MA. PMID: 19147787.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    41. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas. 2008 Aug; 37(2):121-7. Hasan S, Satake M, Dawson DW, Funahashi H, Angst E, Go VL, Reber HA, Hines OJ, Eibl G. PMID: 18665070.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    42. Evaluation of the guidelines for management of pancreatic branch-duct intraductal papillary mucinous neoplasm. Clin Gastroenterol Hepatol. 2008 Jul; 6(7):815-9; quiz 719. Tang RS, Weinberg B, Dawson DW, Reber H, Hines OJ, Tomlinson JS, Chaudhari V, Raman S, Farrell JJ. PMID: 18602036.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    43. Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol. 2006 Nov; 26(22):8475-87. Chen HW, Rainey RN, Balatoni CE, Dawson DW, Troke JJ, Wasiak S, Hong JS, McBride HM, Koehler CM, Teitell MA, French SW. PMID: 16966381.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    44. The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity. Cancer Lett. 2007 Apr 18; 248(2):198-210. French SW, Dawson DW, Chen HW, Rainey RN, Sievers SA, Balatoni CE, Wong L, Troke JJ, Nguyen MT, Koehler CM, Teitell MA. PMID: 16934922.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    45. T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation. J Immunol. 2005 Jul 15; 175(2):864-73. Hoyer KK, Herling M, Bagrintseva K, Dawson DW, French SW, Renard M, Weinger JG, Jones D, Teitell MA. PMID: 16002684.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. Virilization in bilateral macronodular adrenal hyperplasia controlled by luteinizing hormone. J Clin Endocrinol Metab. 2003 Jan; 88(1):73-7. Goodarzi MO, Dawson DW, Li X, Lei Z, Shintaku P, Rao CV, Van Herle AJ. PMID: 12519832.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    47. DNA methylation profiling: a new tool for evaluating hematologic malignancies. Clin Immunol. 2002 Jun; 103(3 Pt 1):217-30. French SW, Dawson DW, Miner MD, Doerr JR, Malone CS, Wall R, Teitell MA. PMID: 12173296.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
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