Dennis Chia • UCLA Profiles

Dennis Jay Chia

Title(s)	HS Associate Clinical Professor, Pediatrics
School	Medicine
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Research

Research Activities and Funding

Epigenetic Actions of Growth Hormone
NIH R03DK092307Jul 1, 2011 - Jun 30, 2013
Role: Principal Investigator

Mechanisms of IGF-I gene transcriptional activation by growth hormone signaling
NIH K08DK077897Sep 20, 2007 - Aug 31, 2013
Role: Principal Investigator

Molecular defect in activation of a mutant Stat5b
NIH F32DK070447Feb 25, 2005 - Feb 24, 2007
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

The Structured Oral Examination: A Method to Improve Formative Assessment of Fellows in Pediatric Endocrinology. Acad Pediatr. 2022 Sep-Oct; 22(7):1091-1096. Shenoy RV, Newbern D, Cooke DW, Chia DJ, Panagiotakopoulos L, DiVall S, Torres-Santiago L, Vangala S, Gupta N. PMID: 34999252.

View in: PubMed Mentions: Fields:
Ped Pediatrics
Translation:Humans
Peak Growth Hormone Response to Combined Stimulation Test in 315 Children and Correlations with Metabolic Parameters. Horm Res Paediatr. 2019; 92(1):36-44. Yau M, Chacko E, Regelmann MO, Annunziato R, Wallach EJ, Chia D, Rapaport R. PMID: 31461713.

View in: PubMed Mentions: 6 Fields:
End Endocrinology Ped Pediatrics
Translation:Humans
Minireview: mechanisms of growth hormone-mediated gene regulation. Mol Endocrinol. 2014 Jul; 28(7):1012-25. Chia DJ. PMID: 24825400; PMCID: PMC4075164.

View in: PubMed Mentions: 63 Fields:
End Endocrinology Mol Molecular Biology
Translation:Humans Animals Cells
Towards identification of molecular mechanisms of short stature. Int J Pediatr Endocrinol. 2013 Nov 20; 2013(1):19. Waldman LA, Chia DJ. PMID: 24257104; PMCID: PMC3835394.

View in: PubMed Mentions: 10
Hepatic-specific accessibility of Igf1 gene enhancers is independent of growth hormone signaling. Mol Endocrinol. 2013 Dec; 27(12):2080-92. Santhanam M, Chia DJ. PMID: 24109593; PMCID: PMC3857198.

View in: PubMed Mentions: 4 Fields:
End Endocrinology Mol Molecular Biology
Translation:Humans Animals Cells
Biochemical characterization of diverse Stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-I gene transcription. PLoS One. 2012; 7(11):e50278. Varco-Merth B, Mirza K, Alzhanov DT, Chia DJ, Rotwein P. PMID: 23185594; PMCID: PMC3502335.

View in: PubMed Mentions: 11 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Defining the epigenetic actions of growth hormone: acute chromatin changes accompany GH-activated gene transcription. Mol Endocrinol. 2010 Oct; 24(10):2038-49. Chia DJ, Rotwein P. PMID: 20702579; PMCID: PMC2954634.

View in: PubMed Mentions: 33 Fields:
End Endocrinology Mol Molecular Biology
Translation:Humans Animals Cells
Dispersed Chromosomal Stat5b-binding elements mediate growth hormone-activated insulin-like growth factor-I gene transcription. J Biol Chem. 2010 Jun 04; 285(23):17636-47. Chia DJ, Varco-Merth B, Rotwein P. PMID: 20378540; PMCID: PMC2878528.

View in: PubMed Mentions: 38 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Distinct alterations in chromatin organization of the two IGF-I promoters precede growth hormone-induced activation of IGF-I gene transcription. Mol Endocrinol. 2010 Apr; 24(4):779-89. Chia DJ, Young JJ, Mertens AR, Rotwein P. PMID: 20160126; PMCID: PMC2852351.

View in: PubMed Mentions: 25 Fields:
End Endocrinology Mol Molecular Biology
Translation:Animals Cells
Gene regulation by growth hormone. Pediatr Nephrol. 2010 Apr; 25(4):651-8. Rotwein P, Chia DJ. PMID: 19626342; PMCID: PMC4244655.

View in: PubMed Mentions: 15 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans Animals Cells
Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone. Mol Endocrinol. 2007 Jun; 21(6):1443-57. Ono M, Chia DJ, Merino-Martinez R, Flores-Morales A, Unterman TG, Rotwein P. PMID: 17426286.

View in: PubMed Mentions: 22 Fields:
End Endocrinology Mol Molecular Biology
Translation:Animals Cells
In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver. Mol Endocrinol. 2007 Jan; 21(1):293-311. Vidal OM, Merino R, Rico-Bautista E, Fernandez-Perez L, Chia DJ, Woelfle J, Ono M, Lenhard B, Norstedt G, Rotwein P, Flores-Morales A. PMID: 17008382.

View in: PubMed Mentions: 38 Fields:
End Endocrinology Mol Molecular Biology
Translation:Humans Animals Cells
Childhood obesity and the metabolic syndrome. Adv Pediatr. 2006; 53:23-53. Chia DJ, Boston BA. PMID: 17089862.

View in: PubMed Mentions: 5 Fields:
Ped Pediatrics
Translation:Humans
Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription. J Biol Chem. 2006 Feb 10; 281(6):3190-7. Chia DJ, Ono M, Woelfle J, Schlesinger-Massart M, Jiang H, Rotwein P. PMID: 16339156.

View in: PubMed Mentions: 41 Fields:
Bio Biochemistry
Translation:Animals Cells
Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction. J Biol Chem. 2006 Mar 10; 281(10):6552-8. Chia DJ, Subbian E, Buck TM, Hwa V, Rosenfeld RG, Skach WR, Shinde U, Rotwein P. PMID: 16303763.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system. Pediatr Nephrol. 2005 Mar; 20(3):295-302. Woelfle J, Chia DJ, Massart-Schlesinger MB, Moyano P, Rotwein P. PMID: 15549418.

View in: PubMed Mentions: 17 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans Animals
Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation. J Biol Chem. 2003 Dec 19; 278(51):51261-6. Woelfle J, Chia DJ, Rotwein P. PMID: 14532269.

View in: PubMed Mentions: 67 Fields:
Bio Biochemistry
Translation:Animals Cells