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Safety and Tolerability of Comprehensive Research Bronchoscopy in Chronic Obstructive Pulmonary Disease. Results from the SPIROMICS Bronchoscopy Substudy. Ann Am Thorac Soc. 2019 04; 16(4):439-446.
Wells JM, Arenberg DA, Barjaktarevic I, Bhatt SP, Bowler RP, Christenson SA, Couper DJ, Dransfield MT, Han MK, Hoffman EA, Kaner RJ, Kim V, Kleerup E, Martinez FJ, Moore WC, O'Beirne SL, Paine R, Putcha N, Raman SM, Barr RG, Rennard SI, Woodruff PG, Curtis JL. PMID: 30653926.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Factors Associated With Progression of Lung Function Abnormalities in HIV-Infected Individuals. . 2018 12 01; 79(4):501-509.
Li Y, Nouraie SM, Kessinger C, Weinman R, Huang L, Greenblatt RM, Kleerup E, Kingsley L, McMahon D, Fitzpatrick M, Morris A. PMID: 30142142.
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Heterogeneous burden of lung disease in smokers with borderline airflow obstruction. Respir Res. 2018 Nov 20; 19(1):223.
Pirozzi CS, Gu T, Quibrera PM, Carretta EE, Han MK, Murray S, Cooper CB, Tashkin DP, Kleerup EC, Barjaktarevic I, Hoffman EA, Martinez CH, Christenson SA, Hansel NN, Graham Barr R, Bleecker ER, Ortega VE, Martinez FJ, Kanner RE, Paine R, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) . PMID: 30454050.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Sleep disruption as a predictor of quality of life among patients in the subpopulations and intermediate outcome measures in COPD study (SPIROMICS). Sleep. 2018 05 01; 41(5).
Zeidler MR, Martin JL, Kleerup EC, Schneider H, Mitchell MN, Hansel NN, Sundar K, Schotland H, Basner RC, Wells JM, Krishnan JA, Criner GJ, Cristenson S, Krachman S, Badr MS, SPIROMICS Research Group . PMID: 29534240.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Human airway branch variation and chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E974-E981.
Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR, Kanner RE, Kaufman JD, Kleerup E, Lin CL, Liu K, Lo Cascio CM, Martinez FJ, Nguyen JN, Prince MR, Rennard S, Rich SS, Simon L, Sun Y, Watson KE, Woodruff PG, Baglole CJ, Barr RG, MESA Lung and SPIROMICS investigators . PMID: 29339516.
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26 Fields:
Translation:
Humans
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Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 12; 5(12):956-967.
Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, Barr RG, Carretta EE, Couper DJ, Cooper CB, Hoffman EA, Kanner RE, Kleerup E, O'Neal WK, Paine R, Peters SP, Alexis NE, Woodruff PG, Han MK, Meyers DA, Bleecker ER, SPIROMICS investigators . PMID: 29146301.
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54 Fields:
Translation:
HumansCells
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Variability in objective and subjective measures affects baseline values in studies of patients with COPD. PLoS One. 2017; 12(9):e0184606.
Anderson WH, Ha JW, Couper DJ, O'Neal WK, Barr RG, Bleecker ER, Carretta EE, Cooper CB, Doerschuk CM, Drummond MB, Han MK, Hansel NN, Kim V, Kleerup EC, Martinez FJ, Rennard SI, Tashkin D, Woodruff PG, Paine R, Curtis JL, Kanner RE, SPIROMICS Research Group . PMID: 28934249.
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5 Fields:
Translation:
Humans
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Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Ann Am Thorac Soc. 2017 May; 14(5):636-642.
Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Krishnan JA, Lazarus SC, Leidy NK, O'Neal W, Martinez FJ, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Han MK, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators . PMID: 28459622.
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12 Fields:
Translation:
Humans
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Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease. AIDS. 2017 02 20; 31(4):539-544.
Morris A, Fitzpatrick M, Bertolet M, Qin S, Kingsley L, Leo N, Kessinger C, Michael H, Mcmahon D, Weinman R, Stone S, Leader JK, Kleerup E, Huang L, Wisniewski SR. PMID: 27941393.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Evaluating small-airways disease in asthmatic patients: The utility of quantitative computed tomography. J Allergy Clin Immunol. 2017 01; 139(1):49-51.e2.
Tashkin DP, Kim HJ, Zeidler M, Kleerup E, Goldin J. PMID: 27884601.
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1 Fields:
Translation:
Humans
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Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial. Lancet Respir Med. 2016 09; 4(9):708-719.
Tashkin DP, Roth MD, Clements PJ, Furst DE, Khanna D, Kleerup EC, Goldin J, Arriola E, Volkmann ER, Kafaja S, Silver R, Steen V, Strange C, Wise R, Wigley F, Mayes M, Riley DJ, Hussain S, Assassi S, Hsu VM, Patel B, Phillips K, Martinez F, Golden J, Connolly MK, Varga J, Dematte J, Hinchcliff ME, Fischer A, Swigris J, Meehan R, Theodore A, Simms R, Volkov S, Schraufnagel DE, Scholand MB, Frech T, Molitor JA, Highland K, Read CA, Fritzler MJ, Kim GHJ, Tseng CH, Elashoff RM, Sclerodema Lung Study II Investigators . PMID: 27469583.
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PubMed Mentions:
173 Fields:
Translation:
Humans
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Novel relationships of markers of monocyte activation and endothelial dysfunction with pulmonary dysfunction in HIV-infected persons. AIDS. 2016 06 01; 30(9):1327-39.
Fitzpatrick ME, Nouraie M, Gingo MR, Camp D, Kessinger CJ, Sincebaugh JB, Clarke A, Ries JW, Kleerup EC, Kingsley L, Morris A. PMID: 26990629.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. N Engl J Med. 2016 May 12; 374(19):1811-21.
Woodruff PG, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Lazarus SC, Martinez FJ, Paine R, Rennard S, Tashkin DP, Han MK, SPIROMICS Research Group . PMID: 27168432.
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183 Fields:
Translation:
Humans
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Transitions to different patterns of interstitial lung disease in scleroderma with and without treatment. Ann Rheum Dis. 2016 Jul; 75(7):1367-71.
Kim HJ, Tashkin DP, Gjertson DW, Brown MS, Kleerup E, Chong S, Belperio JA, Roth MD, Abtin F, Elashoff R, Tseng CH, Khanna D, Goldin JG. PMID: 26757749.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Factors associated with abnormal spirometry among HIV-infected individuals. AIDS. 2015 Aug 24; 29(13):1691-700.
Drummond MB, Huang L, Diaz PT, Kirk GD, Kleerup EC, Morris A, Rom W, Weiden MD, Zhao E, Thompson B, Crothers K. PMID: 26372280.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Medicare Payment Policy Creates Incentives For Long-Term Care Hospitals To Time Discharges For Maximum Reimbursement. Health Aff (Millwood). 2015 Jun; 34(6):907-15.
Kim YS, Kleerup EC, Ganz PA, Ponce NA, Lorenz KA, Needleman J. PMID: 26056194.
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3 Fields:
Translation:
Humans
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Differences between attendings' and fellows' perceptions of futile treatment in the intensive care unit at one academic health center: implications for training. Acad Med. 2015 Mar; 90(3):324-30.
Neville TH, Wiley JF, Holmboe ES, Tseng CH, Vespa P, Kleerup EC, Wenger NS. PMID: 25517700.
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Humans
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Relationship between quantitative radiographic assessments of interstitial lung disease and physiological and clinical features of systemic sclerosis. Ann Rheum Dis. 2016 Feb; 75(2):374-81.
Tashkin DP, Volkmann ER, Tseng CH, Kim HJ, Goldin J, Clements P, Furst D, Khanna D, Kleerup E, Roth MD, Elashoff R. PMID: 25452309.
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21 Fields:
Translation:
Humans
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The opportunity cost of futile treatment in the ICU*. Crit Care Med. 2014 Sep; 42(9):1977-82.
Huynh TN, Kleerup EC, Raj PP, Wenger NS. PMID: 24810527.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Acute bronchodilator responses decline progressively over 4 years in patients with moderate to very severe COPD. Respir Res. 2014 Aug 31; 15:102.
Tashkin DP, Li N, Kleerup EC, Halpin D, Celli B, Decramer M, Elashoff R. PMID: 25175805.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. J Transl Med. 2014 Jan 08; 12:9.
O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R, Woodruff PG, Couper DJ, Davis SM, SPIROMICS Investigators . PMID: 24397870.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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The frequency and cost of treatment perceived to be futile in critical care. JAMA Intern Med. 2013 Nov 11; 173(20):1887-94.
Huynh TN, Kleerup EC, Wiley JF, Savitsky TD, Guse D, Garber BJ, Wenger NS. PMID: 24018712.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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HIV infection is associated with diffusing capacity impairment in women. . 2013 Nov 01; 64(3):284-8.
Fitzpatrick ME, Gingo MR, Kessinger C, Lucht L, Kleerup E, Greenblatt RM, Claman D, Ponath C, Fong S, Huang L, Morris A. PMID: 23979000.
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PubMed Mentions:
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HIV infection is associated with reduced pulmonary diffusing capacity. . 2013 Nov 01; 64(3):271-8.
Crothers K, McGinnis K, Kleerup E, Wongtrakool C, Hoo GS, Kim J, Sharafkhaneh A, Huang L, Luo Z, Thompson B, Diaz P, Kirk GD, Rom W, Detels R, Kingsley L, Morris A. PMID: 23979001.
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Factors associated with palliative withdrawal of mechanical ventilation and time to death after withdrawal. J Palliat Med. 2013 Nov; 16(11):1368-74.
Huynh TN, Walling AM, Le TX, Kleerup EC, Liu H, Wenger NS. PMID: 24083651.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 2014 May; 69(5):491-4.
Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff PG, Rennard S, SPIROMICS Research Group . PMID: 24029743.
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PubMed Mentions:
148 Fields:
Translation:
Humans
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Annual rates of change in pre- vs. post-bronchodilator FEV1 and FVC over 4 years in moderate to very severe COPD. Respir Med. 2013 Dec; 107(12):1904-11.
Tashkin DP, Li N, Halpin D, Kleerup E, Decramer M, Celli B, Elashoff R. PMID: 23972968.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Prognostic factors and outcomes of patients with pulmonary hypertension admitted to the intensive care unit. J Crit Care. 2012 Dec; 27(6):739.e7-13.
Huynh TN, Weigt SS, Sugar CA, Shapiro S, Kleerup EC. PMID: 23089677.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Comparison of the variability of the annual rates of change in FEV1 determined from serial measurements of the pre- versus post-bronchodilator FEV1 over 5 years in mild to moderate COPD: results of the lung health study. Respir Res. 2012 Aug 15; 13:70.
Tashkin DP, Wang HJ, Halpin D, Kleerup EC, Connett J, Li N, Elashoff R. PMID: 22894725.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Quantitative texture-based assessment of one-year changes in fibrotic reticular patterns on HRCT in scleroderma lung disease treated with oral cyclophosphamide. Eur Radiol. 2011 Dec; 21(12):2455-65.
Kim HJ, Brown MS, Elashoff R, Li G, Gjertson DW, Lynch DA, Strollo DC, Kleerup E, Chong D, Shah SK, Ahmad S, Abtin F, Tashkin DP, Goldin JG. PMID: 21927793.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Predicting treatment outcomes and responder subsets in scleroderma-related interstitial lung disease. Arthritis Rheum. 2011 Sep; 63(9):2797-808.
Roth MD, Tseng CH, Clements PJ, Furst DE, Tashkin DP, Goldin JG, Khanna D, Kleerup EC, Li N, Elashoff D, Elashoff RM, Scleroderma Lung Study Research Group . PMID: 21547897.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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HIV and chronic obstructive pulmonary disease: is it worse and why? Proc Am Thorac Soc. 2011 Jun; 8(3):320-5.
Morris A, George MP, Crothers K, Huang L, Lucht L, Kessinger C, Kleerup EC, Lung HIV Study . PMID: 21653535.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Time course and degree of hyperinflation with metronome-paced tachypnea in COPD patients. COPD. 2008 Oct; 5(5):298-304.
Weigt SS, Abrazado M, Kleerup EC, Tashkin DP, Cooper CB. PMID: 18972278.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Quality indicators for the care of chronic obstructive pulmonary disease in vulnerable elders. J Am Geriatr Soc. 2007 Oct; 55 Suppl 2:S270-6.
Kleerup E. PMID: 17910547.
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PubMed Mentions:
2 Fields:
Translation:
HumansPHPublic Health
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Small airways response to naturalistic cat allergen exposure in subjects with asthma. J Allergy Clin Immunol. 2006 Nov; 118(5):1075-81.
Zeidler MR, Goldin JG, Kleerup EC, Kim HJ, Truong DA, Gjertson DW, Kennedy NJ, Newman KB, Tashkin DP, Silverman JM, Corren J. PMID: 17088132.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Regional differences in bronchoalveolar lavage and thoracic high-resolution computed tomography results in dyspneic patients with systemic sclerosis. Arthritis Rheum. 2004 Jun; 50(6):1909-17.
Clements PJ, Goldin JG, Kleerup EC, Furst DE, Elashoff RM, Tashkin DP, Roth MD. PMID: 15188367.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Exhaled nitric oxide in the assessment of asthma. Curr Opin Pulm Med. 2004 Jan; 10(1):31-6.
Zeidler MR, Kleerup EC, Tashkin DP. PMID: 14749603.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Chronic and acute effects of "crack" cocaine on diffusing capacity, membrane diffusion, and pulmonary capillary blood volume in the lung. Chest. 2002 Aug; 122(2):629-38.
Kleerup EC, Koyal SN, Marques-Magallanes JA, Goldman MD, Tashkin DP. PMID: 12171843.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Evidence of chronic damage to the pulmonary microcirculation in habitual users of alkaloidal ("crack") cocaine. Chest. 2002 Apr; 121(4):1231-8.
Baldwin GC, Choi R, Roth MD, Shay AH, Kleerup EC, Simmons MS, Tashkin DP. PMID: 11948058.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells