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Zeng, Gang

Title(s)Adjunct Professor, Urology
Phone47635
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    Collapse Research 
    Collapse Research Activities and Funding
    Autoantibodies against micro RNA for Early Cancer Detection
    NIH/NCI R21CA195222Apr 1, 2015 - Mar 31, 2017
    Role: Principal Investigator
    A+PSA Assay for Improved Prostate Cancer Diagnosis and Risk Assessment
    NIH/NCI R01CA164388Mar 12, 2012 - Feb 29, 2016
    Role: Principal Investigator
    Auto-antibody plus PSA assay for patients with prostate cancer
    NIH/NCI R21CA137651Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Epitope Array to Complement PSA Tests for Early Detection of Prostate Cancer
    NIH/NCI R03CA128086Apr 1, 2007 - Mar 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee MH, Yanagawa J, Tran L, Walser TC, Bisht B, Fung E, Park SJ, Zeng G, Krysan K, Wallace WD, Paul MK, Girard L, Gao B, Minna JD, Dubinett SM, Lee JM. FRA1 contributes to MEK-ERK pathway-dependent PD-L1 upregulation by KRAS mutation in premalignant human bronchial epithelial cells. Am J Transl Res. 2020; 12(2):409-427. PMID: 32194893.
      View in: PubMed
    2. Gong D, Zhang TH, Zhao D, Du Y, Chapa TJ, Shi Y, Wang L, Contreras D, Zeng G, Shi PY, Wu TT, Arumugaswami V, Sun R. High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells. iScience. 2018 Mar 23; 1:97-111. PMID: 30227960.
      View in: PubMed
    3. Wang M, Lomeli SH, Franklin WA, Lee S, Pantuck AJ, Zeng G. Optimizing peptide epitope-based autoantibody detection in cancer patients. Am J Clin Exp Immunol. 2017; 6(5):84-91. PMID: 29181273.
      View in: PubMed
    4. Lee JM, Lee MH, Garon E, Goldman JW, Salehi-Rad R, Baratelli FE, Schaue D, Wang G, Rosen F, Yanagawa J, Walser TC, Lin Y, Park SJ, Adams S, Marincola FM, Tumeh PC, Abtin F, Suh R, Reckamp KL, Lee G, Wallace WD, Lee S, Zeng G, Elashoff DA, Sharma S, Dubinett SM. Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration. Clin Cancer Res. 2017 Aug 15; 23(16):4556-4568. PMID: 28468947.
      View in: PubMed
    5. Yu W, Qin X, Jin Y, Li Y, Santiskulvong C, Vu V, Zeng G, Zhang Z, Chow M, Rao J. Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter. Oncotarget. 2017 Jan 31; 8(5):7977-7988. PMID: 28002788.
      View in: PubMed
    6. Shih J, Rahman M, Luong QT, Lomeli SH, Riss J, Prins RM, Gure AO, Zeng G. Dominant B-cell epitopes from cancer/stem cell antigen SOX2 recognized by serum samples from cancer patients. Am J Clin Exp Immunol. 2014; 3(2):84-90. PMID: 25143868.
      View in: PubMed
    7. Lu S, Qin X, Yuan S, Li Y, Wang L, Jin Y, Zeng G, Yen L, Hu J, Dang T, Song S, Hou Q, Rao J. Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies. Int J Clin Exp Med. 2014; 7(3):597-606. PMID: 24753753.
      View in: PubMed
    8. Xu L, Zheng J, Nguyen DH, Luong QT, Zeng G. Enhancing whole-tumor cell vaccination by engaging innate immune system through NY-ESO-1/dendritic cell interactions. J Immunother. 2013 Oct; 36(8):412-22. PMID: 23994888.
      View in: PubMed
    9. Seiler D, Zheng J, Liu G, Wang S, Yamashiro J, Reiter RE, Huang J, Zeng G. Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines. Prostate. 2013 Sep; 73(13):1378-90. PMID: 23728788.
      View in: PubMed
    10. Liu Y, Zeng G. Cancer and innate immune system interactions: translational potentials for cancer immunotherapy. J Immunother. 2012 May; 35(4):299-308. PMID: 22495387.
      View in: PubMed
    11. Liu Y, Tian X, Leitner WW, Aldridge ME, Zheng J, Yu Z, Restifo NP, Weiss R, Scheiblhofer S, Xie C, Sun R, Cheng G, Zeng G. Polymeric structure and host Toll-like receptor 4 dictate immunogenicity of NY-ESO-1 antigen in vivo. J Biol Chem. 2011 Oct 28; 286(43):37077-84. PMID: 21900253.
      View in: PubMed
    12. Meng Z, Wang Y, Zhang G, Ke Y, Yan Y, Wu L, Huang Q, Zeng G, Wang Y, Ying H, Jiao S. Identification of an HLA-DPB1*0501 restricted Melan-A/MART-1 epitope recognized by CD4+ T lymphocytes: prevalence for immunotherapy in Asian populations. J Immunother. 2011 Sep; 34(7):525-34. PMID: 21760531.
      View in: PubMed
    13. Xie C, Kim HJ, Haw JG, Kalbasi A, Gardner BK, Li G, Rao J, Chia D, Liong M, Punzalan RR, Marks LS, Pantuck AJ, de la Taille A, Wang G, Mukouyama H, Zeng G. A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases. J Transl Med. 2011 Apr 19; 9:43. PMID: 21504557.
      View in: PubMed
    14. Baratelli F, Takedatsu H, Hazra S, Peebles K, Luo J, Kurimoto PS, Zeng G, Batra RK, Sharma S, Dubinett SM, Lee JM. Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer. J Transl Med. 2008 Jul 22; 6:38. PMID: 18644162.
      View in: PubMed
    15. Shvarts O, Janzen N, Lam JS, Leppert JT, Caliliw R, Figlin RA, Belldegrun AS, Zeng G. RENCA/carbonic anhydrase-IX: a murine model of a carbonic anhydrase-IX-expressing renal cell carcinoma. Urology. 2006 Nov; 68(5):1132-8. PMID: 17095063.
      View in: PubMed
    16. Zeng G, Aldridge ME, Tian X, Seiler D, Zhang X, Jin Y, Rao J, Li W, Chen D, Langford MP, Duggan C, Belldegrun AS, Dubinett SM. Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system. J Immunol. 2006 Sep 15; 177(6):3582-9. PMID: 16951317.
      View in: PubMed
    17. Lam JS, Seligson DB, Yu H, Li A, Eeva M, Pantuck AJ, Zeng G, Horvath S, Belldegrun AS. Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score. BJU Int. 2006 Aug; 98(2):445-51. PMID: 16879693.
      View in: PubMed
    18. Baratelli F, Lin Y, Zhu L, Yang SC, Heuzé-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol. 2005 Aug 01; 175(3):1483-90. PMID: 16034085.
      View in: PubMed
    19. Zeng G, Aldridge ME, Wang Y, Pantuck AJ, Wang AY, Liu YX, Han Y, Yuan YH, Robbins PF, Dubinett SM, deKernion JB, Belldegrun AS. Dominant B cell epitope from NY-ESO-1 recognized by sera from a wide spectrum of cancer patients: implications as a potential biomarker. Int J Cancer. 2005 Mar 20; 114(2):268-73. PMID: 15540228.
      View in: PubMed
    20. Liu G, Yu JS, Zeng G, Yin D, Xie D, Black KL, Ying H. AIM-2: a novel tumor antigen is expressed and presented by human glioma cells. J Immunother. 2004 May-Jun; 27(3):220-6. PMID: 15076139.
      View in: PubMed
    21. Mukouyama H, Janzen NK, Hernandez JM, Lam JS, Caliliw R, Wang AY, Figlin RA, Belldegrun AS, Zeng G. Generation of kidney cancer-specific antitumor immune responses using peripheral blood monocytes transduced with a recombinant adenovirus encoding carbonic anhydrase 9. Clin Cancer Res. 2004 Feb 15; 10(4):1421-9. PMID: 14977845.
      View in: PubMed
    22. Pantuck AJ, Zeng G, Belldegrun AS, Figlin RA. Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway. Clin Cancer Res. 2003 Oct 15; 9(13):4641-52. PMID: 14581333.
      View in: PubMed
    23. Robbins PF, El-Gamil M, Li YF, Zeng G, Dudley M, Rosenberg SA. Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma. J Immunol. 2002 Nov 15; 169(10):6036-47. PMID: 12421991.
      View in: PubMed
    24. Zeng G, Li Y, El-Gamil M, Sidney J, Sette A, Wang RF, Rosenberg SA, Robbins PF. Generation of NY-ESO-1-specific CD4+ and CD8+ T cells by a single peptide with dual MHC class I and class II specificities: a new strategy for vaccine design. Cancer Res. 2002 Jul 01; 62(13):3630-5. PMID: 12097265.
      View in: PubMed