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Gautam Chaudhuri

Title(s)Professor, Obstetrics and Gynecology
SchoolMedicine
Address760 Westwood Plaza 27-126
Los Angeles CA 90024
Phone310-794-1912
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    Other Positions
    Title(s)Professor, Molecular and Medical Pharmacology


    Collapse Research 
    Collapse Research Activities and Funding
    Gamma-Aminobutyric Acid is Synthesized by Endothelial Cells: Implications in Preeclampsia
    NIH/NHLBI R01HL135606Jul 1, 2017 - Jun 30, 2021
    Role: Principal Investigator
    Pregnancy, Pre-eclampsia, Anti-oxidants and Endothelial Cell Function
    NIH/NHLBI R01HL083038Aug 1, 2006 - Jul 31, 2011
    Role: Principal Investigator
    ROLE OF NO AND ESTRADIOL IN AGING AND ATHEROGENESIS
    NIH/NIA R01AG015857Sep 30, 2000 - Aug 31, 2006
    Role: Principal Investigator
    Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Center
    NIH/NICHD K12HD001400Aug 30, 2000 - Jul 31, 2012
    Role: Principal Investigator
    ESTRADIOL, NITRIC OXIDE AND CYCLIN D1 IN BREAST CANCER
    NIH/NCI R01CA078357Jul 1, 2000 - Jun 30, 2006
    Role: Principal Investigator
    UCLA Women's Reproductive Health Research Center
    NIH/NICHD K12HD001281Sep 30, 1998 - Nov 30, 2003
    Role: Principal Investigator
    PREGNANCY AND GI MOTILITY: ROLE OF NITRIC OXIDE
    NIH/NICHD R01HD035991Feb 1, 1998 - Jan 31, 2005
    Role: Principal Investigator
    DNA ANTISENSE APPROACH AGAINST LEISHMANIASIS
    NIH/NIAID R01AI042327Dec 15, 1997 - Nov 30, 2001
    Role: Principal Investigator
    EDNO AND UTERINE BLOOD FLOW IN PREGNANCY
    NIH/NHLBI R01HL046843Aug 1, 1991 - Mar 31, 2001
    Role: Principal Investigator
    EDRF AND PROSTACYCLIN IN HUMAN UMBILICAL VESSELS
    NIH/NICHD R01HD031467Aug 1, 1989 - Jul 31, 1999
    Role: Principal Investigator
    EDRF AND PROSTACYCLIN IN HUMAN UMBILICAL VESSELS
    NIH/NHLBI R01HL040872Aug 1, 1989 - Mar 31, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Carbon monoxide sensitizes cisplatin-resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein. J Inorg Biochem. 2019 02; 191:29-39. Kawahara B, Ramadoss S, Chaudhuri G, Janzen C, Sen S, Mascharak PK. PMID: 30458366.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    2. The Role of Epithelial to Mesenchymal Transition in Human Amniotic Membrane Rupture. J Clin Endocrinol Metab. 2017 04 01; 102(4):1261-1269. Janzen C, Sen S, Lei MY, Gagliardi de Assumpcao M, Challis J, Chaudhuri G. PMID: 28388726.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    3. ?-Aminobutyric Acid Is Synthesized and Released by the Endothelium: Potential Implications. Circ Res. 2016 Aug 19; 119(5):621-34. Sen S, Roy S, Bandyopadhyay G, Scott B, Xiao D, Ramadoss S, Mahata SK, Chaudhuri G. PMID: 27354210.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    4. Cystathionine: A novel oncometabolite in human breast cancer. Arch Biochem Biophys. 2016 08 15; 604:95-102. Sen S, Kawahara B, Mahata SK, Tsai R, Yoon A, Hwang L, Hu-Moore K, Villanueva C, Vajihuddin A, Parameshwar P, You M, Bhaskar DL, Gomez O, Faull KF, Farias-Eisner R, Chaudhuri G. PMID: 27311614.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. Role of cystathionine ß-synthase in human breast Cancer. Free Radic Biol Med. 2015 Sep; 86:228-38. Sen S, Kawahara B, Gupta D, Tsai R, Khachatryan M, Roy-Chowdhuri S, Bose S, Yoon A, Faull K, Farias-Eisner R, Chaudhuri G. PMID: 26051168.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    6. Acid gradient across plasma membrane can drive phosphate bond synthesis in cancer cells: acidic tumor milieu as a potential energy source. PLoS One. 2015; 10(4):e0124070. Dhar G, Sen S, Chaudhuri G. PMID: 25874623.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Gestational diabetes, preeclampsia and cytokine release: similarities and differences in endothelial cell function. Adv Exp Med Biol. 2014; 814:69-75. Rao R, Sen S, Han B, Ramadoss S, Chaudhuri G. PMID: 25015801.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. A light-activated NO donor attenuates anchorage independent growth of cancer cells: Important role of a cross talk between NO and other reactive oxygen species. Arch Biochem Biophys. 2013 Dec; 540(1-2):33-40. Sen S, Kawahara B, Fry NL, Farias-Eisner R, Zhang D, Mascharak PK, Chaudhuri G. PMID: 24157690.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Endothelial cell function in utero-placental circulation physiology and pathophysiology. Curr Vasc Pharmacol. 2013 Sep; 11(5):730-6. Sen S, Rao R, Chaudhuri G. PMID: 24063384.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Induction of a feed forward pro-apoptotic mechanistic loop by nitric oxide in a human breast cancer model. PLoS One. 2013; 8(8):e70593. Sen S, Kawahara B, Fukuto J, Chaudhuri G. PMID: 23950968.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy. PLoS One. 2013; 8(1):e53287. Pervin S, Hewison M, Braga M, Tran L, Chun R, Karam A, Chaudhuri G, Norris K, Singh R. PMID: 23341935.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    12. Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: implications for breast cancer. Free Radic Biol Med. 2013 Apr; 57:210-20. Sen S, Kawahara B, Chaudhuri G. PMID: 23089229.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    13. Maintenance of higher H2O2 levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2A. Free Radic Biol Med. 2012 Oct 15; 53(8):1541-51. Sen S, Kawahara B, Chaudhuri G. PMID: 22749807.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    14. Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-a. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2586-94. Janzen C, Sen S, Cuevas J, Reddy ST, Chaudhuri G. PMID: 21903942.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. J Neurosci Res. 2010 Nov 15; 88(15):3386-98. Fung C, Evans E, Shin D, Shin BC, Zhao Y, Sankar R, Chaudhuri G, Devaskar SU. PMID: 20857507.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    16. NO to breast: when, why and why not? Curr Pharm Des. 2010; 16(4):451-62. Pervin S, Chaudhuri G, Singh R. PMID: 20236074.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    17. Serum levels of soluble vascular cell adhesion molecule-1, tumor necrosis factor-alpha, and interleukin-6 in in vitro fertilization cycles. Fertil Steril. 2009 May; 91(5 Suppl):2012-9. Souter I, Huang A, Martinez-Maza O, Breen EC, Decherney AH, Chaudhuri G, Nathan L. PMID: 18778820.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis. Cancer Res. 2008 Jun 15; 68(12):4862-74. Pervin S, Tran AH, Zekavati S, Fukuto JM, Singh R, Chaudhuri G. PMID: 18559534.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    19. Nitric oxide, N omega-hydroxy-L-arginine and breast cancer. Nitric Oxide. 2008 Sep; 19(2):103-6. Pervin S, Singh R, Chaudhuri G. PMID: 18474257.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Nuclear receptors and female reproduction: a tale of 3 scientists, Jensen, Gustafsson, and O'Malley. Reprod Sci. 2008 Feb; 15(2):110-20. Chaudhuri G. PMID: 18276948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. A past medical history of gestational diabetes: its medical significance and its dental implications. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb; 103(2):157-63. Friedlander AH, Chaudhuri G, Altman L. PMID: 17234528.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer Res. 2007 Jan 01; 67(1):289-99. Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G. PMID: 17210710.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    23. Serum levels of soluble vascular cell adhesion molecule-1 are decreased in women receiving oral contraceptives compared with normally menstruating women: implications in atherosclerosis. Fertil Steril. 2005 May; 83(5):1480-8. Souter I, Janzen C, Martinez-Maza O, Breen EC, Stanczyk F, Chaudhuri G, Nathan L. PMID: 15866588.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells. Biochem Biophys Res Commun. 2005 Apr 08; 329(2):508-15. Tripathi MK, Misra S, Chaudhuri G. PMID: 15737616.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    25. MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer. Cancer Res. 2003 Dec 15; 63(24):8853-60. Pervin S, Singh R, Freije WA, Chaudhuri G. PMID: 14695202.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    26. Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: essential role of Akt. Cancer Res. 2003 Sep 01; 63(17):5470-9. Pervin S, Singh R, Chaudhuri G. PMID: 14500383.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    27. 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem. 2003 Apr 04; 278(14):11746-52. Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. PMID: 12547825.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    28. Caspase-8-mediated BID cleavage and release of mitochondrial cytochrome c during Nomega-hydroxy-L-arginine-induced apoptosis in MDA-MB-468 cells. Antagonistic effects of L-ornithine. J Biol Chem. 2002 Oct 04; 277(40):37630-6. Singh R, Pervin S, Chaudhuri G. PMID: 12145284.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    29. Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):4055-60. Mukherjee TK, Dinh H, Chaudhuri G, Nathan L. PMID: 11904449.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    30. Noninvasive assessment of coronary microcirculatory function in postmenopausal women and effects of short-term and long-term estrogen administration. Circulation. 2002 Jan 29; 105(4):425-30. Campisi R, Nathan L, Pampaloni MH, Schöder H, Sayre JW, Chaudhuri G, Schelbert HR. PMID: 11815423.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
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