Guido Eibl

Title(s)Professor-in-Residence, Surgery
SchoolMedicine
Address
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    Collapse Research 
    Collapse Research Activities and Funding
    Chemoprevention and mechanisms of obesity-promoted pancreatic adenocarcinoma
    NIH P01CA236585May 1, 2020 - Apr 30, 2025
    Role: Principal Investigator
    Targeting diet-induced promotion of Kras-initiated pancreatic adenocarcinoma
    NIH P01CA163200Aug 1, 2012 - Jul 31, 2019
    Role: Principal Investigator
    The role of n-3 polyunsaturated fatty acids in pancreatic cancer
    NIH R01CA122042Aug 1, 2007 - May 31, 2013
    Role: Principal Investigator
    The Role of COX-2 and PPAR-Gamma in Pancreatic Cancer
    NIH R01CA104027Mar 1, 2004 - Feb 28, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Metformin: review of epidemiology and mechanisms of action in pancreatic cancer. Cancer Metastasis Rev. 2021 Jun 17. Eibl G, Rozengurt E. PMID: 34142285.
      View in: PubMed   Mentions:    Fields:    
    2. Direct Effects of Lipopolysaccharide on Human Pancreatic Cancer Cells. Pancreas. 2021 Apr 01; 50(4):524-528. Massoumi RL, Teper Y, Ako S, Ye L, Wang E, Hines OJ, Eibl G. PMID: 33939664.
      View in: PubMed   Mentions:    Fields:    
    3. Endocrine-exocrine signals in obesity-associated pancreatic cancer. Nat Rev Gastroenterol Hepatol. 2020 08; 17(8):455-456. Eibl G. PMID: 32483354.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Pancreatic Macrophages: Critical Players in Obesity-Promoted Pancreatic Cancer. Cancers (Basel). 2020 Jul 17; 12(7). Teper Y, Eibl G. PMID: 32709161.
      View in: PubMed   Mentions:
    5. The Diverse Involvement of Cigarette Smoking in Pancreatic Cancer Development and Prognosis. Pancreas. 2020 May/Jun; 49(5):612-620. Weissman S, Takakura K, Eibl G, Pandol SJ, Saruta M. PMID: 32433397.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity. Am J Physiol Gastrointest Liver Physiol. 2019 12 01; 317(6):G763-G772. Dong TS, Chang HH, Hauer M, Lagishetty V, Katzka W, Rozengurt E, Jacobs JP, Eibl G. PMID: 31545922.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    7. Obesity-Induced Adipose Tissue Inflammation as a Strong Promotional Factor for Pancreatic Ductal Adenocarcinoma. Cells. 2019 07 03; 8(7). Chang HH, Eibl G. PMID: 31277269.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    8. Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer. Pancreas. 2019 07; 48(6):759-779. Saloman JL, Albers KM, Cruz-Monserrate Z, Davis BM, Edderkaoui M, Eibl G, Epouhe AY, Gedeon JY, Gorelick FS, Grippo PJ, Groblewski GE, Husain SZ, Lai KKY, Pandol SJ, Uc A, Wen L, Whitcomb DC. PMID: 31206467.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    9. Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. PLoS One. 2019; 14(5):e0216603. Hao F, Xu Q, Wang J, Yu S, Chang HH, Sinnett-Smith J, Eibl G, Rozengurt E. PMID: 31100067.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    10. Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development. World J Gastroenterol. 2019 Apr 21; 25(15):1797-1816. Rozengurt E, Eibl G. PMID: 31057295.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    11. Emerging Evidence for the Clinical Relevance of Pancreatic Cancer Exosomes. Pancreas. 2019 01; 48(1):1-8. Massoumi RL, Hines OJ, Eibl G, King JC. PMID: 30531240.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    12. Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California. J Obes. 2018; 2018:7014073. Juo YY, Gibbons MAM, Dutson E, Lin AY, Yanagawa J, Hines OJ, Eibl G, Chen Y. PMID: 30327727.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice. BMC Cancer. 2018 Aug 07; 18(1):797. Xu M, Chang HH, Jung X, Moro A, Chou CEN, King J, Hines OJ, Sinnett-Smith J, Rozengurt E, Eibl G. PMID: 30086728.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    14. Deficiencies in Natural Killer Cell Numbers, Expansion, and Function at the Pre-Neoplastic Stage of Pancreatic Cancer by KRAS Mutation in the Pancreas of Obese Mice. Front Immunol. 2018; 9:1229. Kaur K, Chang HH, Topchyan P, Cook JM, Barkhordarian A, Eibl G, Jewett A. PMID: 29977235.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    15. Strategies to Prevent Obesity-Related Cancer. JAMA. 2018 06 19; 319(23):2442. Chen Y, Dutson E, Eibl G. PMID: 29922821.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2018 May/Jun; 47(5):516-525. Abbruzzese JL, Andersen DK, Borrebaeck CAK, Chari ST, Costello E, Cruz-Monserrate Z, Eibl G, Engleman EG, Fisher WE, Habtezion A, Kim SK, Korc M, Logsdon C, Lyssiotis CA, Pandol SJ, Rustgi A, Wolfe BM, Zheng L, Powers AC. PMID: 29702529.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival. Signal Transduct Target Ther. 2018; 3:11. Rozengurt E, Sinnett-Smith J, Eibl G. PMID: 29682330.
      View in: PubMed   Mentions:
    18. Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model. Sci Rep. 2018 04 12; 8(1):5899. Chang HH, Moro A, Chou CEN, Dawson DW, French S, Schmidt AI, Sinnett-Smith J, Hao F, Hines OJ, Eibl G, Rozengurt E. PMID: 29651002.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    19. Obesity and Pancreatic Cancer: Overview of Epidemiology and Potential Prevention by Weight Loss. Pancreas. 2018 02; 47(2):158-162. Xu M, Jung X, Hines OJ, Eibl G, Chen Y. PMID: 29346216.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    20. Suppression of Gingival NK Cells in Precancerous and Cancerous Stages of Pancreatic Cancer in KC and BLT-Humanized Mice. Front Immunol. 2017; 8:1606. Kaur K, Chang HH, Cook J, Eibl G, Jewett A. PMID: 29255459.
      View in: PubMed   Mentions: 4     Fields:    
    21. KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops. Semin Cancer Biol. 2019 02; 54:50-62. Eibl G, Rozengurt E. PMID: 29079305.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    22. Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer. J Acad Nutr Diet. 2018 04; 118(4):555-567. Eibl G, Cruz-Monserrate Z, Korc M, Petrov MS, Goodarzi MO, Fisher WE, Habtezion A, Lugea A, Pandol SJ, Hart PA, Andersen DK, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer . PMID: 28919082.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    23. Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice. PLoS One. 2017; 12(9):e0184455. Chang HH, Moro A, Takakura K, Su HY, Mo A, Nakanishi M, Waldron RT, French SW, Dawson DW, Hines OJ, Li G, Go VLW, Sinnett-Smith J, Pandol SJ, Lugea A, Gukovskaya AS, Duff MO, Rosenberg DW, Rozengurt E, Eibl G. PMID: 28886117.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    24. Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer. Diabetes. 2017 05; 66(5):1103-1110. Andersen DK, Korc M, Petersen GM, Eibl G, Li D, Rickels MR, Chari ST, Abbruzzese JL. PMID: 28507210.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    25. Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism. Surgery. 2017 06; 161(6):1570-1578. Schmidt A, Sinnett-Smith J, Young S, Chang HH, Hines OJ, Dawson DW, Rozengurt E, Eibl G. PMID: 28222855.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G675-G687. Yang J, Waldron RT, Su HY, Moro A, Chang HH, Eibl G, Ferreri K, Kandeel FR, Lugea A, Li L, Pandol SJ. PMID: 27609771.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    27. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1124-37. Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. PMID: 27151939.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    28. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 Mar; 45(3):458-65. Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. PMID: 26495779.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    29. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 06; 159(6):1520-1527. Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. PMID: 26847803.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    30. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 Jan; 45(1):21-31. Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. PMID: 26658038.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    31. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. . 2015 Nov 15; 309(10):C639-49. Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. PMID: 26310818.
      View in: PubMed   Mentions:
    32. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 Dec; 158(6):1564-72. Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. PMID: 26297056.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    33. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PLoS One. 2014; 9(12):e114573. Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. PMID: 25493642.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    34. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Front Physiol. 2014; 5:490. Edderkaoui M, Eibl G. PMID: 25540626.
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    35. Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells. Nutr Cancer. 2013; 65(8):1232-44. Edderkaoui M, Lugea A, Hui H, Eibl G, Lu QY, Moro A, Lu X, Li G, Go VL, Pandol SJ. PMID: 24127740.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    36. Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue ß-glucuronidase. J Pharm Biomed Anal. 2014 Jan; 88:364-9. Lu QY, Zhang L, Eibl G, Go VL. PMID: 24176739.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells. Biochem Biophys Res Commun. 2013 Sep 13; 439(1):6-11. Pham H, Rodriguez CE, Donald GW, Hertzer KM, Jung XS, Chang HH, Moro A, Reber HA, Hines OJ, Eibl G. PMID: 23973710.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    38. Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells. Biochim Biophys Acta. 2013 Dec; 1833(12):2980-2987. Takahashi H, Chen MC, Pham H, Matsuo Y, Ishiguro H, Reber HA, Takeyama H, Hines OJ, Eibl G. PMID: 23954445.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    39. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer Prev Res (Phila). 2013 Oct; 6(10):1064-73. Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. PMID: 23943783.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    40. Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem. 2013 Sep 13; 288(37):26888-97. Lau C, Kim Y, Chia D, Spielmann N, Eibl G, Elashoff D, Wei F, Lin YL, Moro A, Grogan T, Chiang S, Feinstein E, Schafer C, Farrell J, Wong DT. PMID: 23880764.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    41. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 Jul; 42(5):781-5. Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. PMID: 23462329.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    42. Perioperative antibiotics for surgical site infection in pancreaticoduodenectomy: does the SCIP-approved regimen provide adequate coverage? Surgery. 2013 Aug; 154(2):190-6. Donald GW, Sunjaya D, Lu X, Chen F, Clerkin B, Eibl G, Li G, Tomlinson JS, Donahue TR, Reber HA, Hines OJ. PMID: 23664266.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    43. The flavonoid quercetin inhibits pancreatic cancer growth in vitro and in vivo. Pancreas. 2013 Mar; 42(2):223-9. Angst E, Park JL, Moro A, Lu QY, Lu X, Li G, King J, Chen M, Reber HA, Go VL, Eibl G, Hines OJ. PMID: 23000892.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    44. Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. J Chromatogr Sep Tech. 2013 Jan 01; 4(1). Lu QY, Zhang L, Lugea A, Moro A, Edderkaoui M, Eibl G, Pandol SJ, Go VL. PMID: 24482742.
      View in: PubMed   Mentions:
    45. Baicalein--an intriguing therapeutic phytochemical in pancreatic cancer. Curr Drug Targets. 2012 Dec; 13(14):1772-6. Donald G, Hertzer K, Eibl G. PMID: 23140288.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    46. Apigenin inhibits NNK-induced focal adhesion kinase activation in pancreatic cancer cells. Pancreas. 2012 Nov; 41(8):1306-15. Pham H, Chen M, Takahashi H, King J, Reber HA, Hines OJ, Pandol S, Eibl G. PMID: 22889981.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    47. Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. Pancreas. 2012 May; 41(4):571-6. Lu QY, Zhang L, Moro A, Chen MC, Harris DM, Eibl G, Go VL. PMID: 22158070.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    48. Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell. J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:127-34. Pandol S, Gukovskaya A, Edderkaoui M, Edderkoui M, Dawson D, Eibl G, Lugea A. PMID: 22320930.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    49. Evidence for activation of mutated p53 by apigenin in human pancreatic cancer. Biochim Biophys Acta. 2012 Feb; 1823(2):593-604. King JC, Lu QY, Li G, Moro A, Takahashi H, Chen M, Go VL, Reber HA, Eibl G, Hines OJ. PMID: 22227579.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    50. The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. Gastroenterology. 2012 Feb; 142(2):377-87.e1-5. Nitsche C, Edderkaoui M, Moore RM, Eibl G, Kasahara N, Treger J, Grippo PJ, Mayerle J, Lerch MM, Gukovskaya AS. PMID: 22044669.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    51. Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials. Surgery. 2011 Sep; 150(3):466-73. Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ. PMID: 21878232.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    52. Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. Biochim Biophys Acta. 2011 Aug; 1813(8):1465-74. Takahashi H, Chen MC, Pham H, Angst E, King JC, Park J, Brovman EY, Ishiguro H, Harris DM, Reber HA, Hines OJ, Gukovskaya AS, Go VL, Eibl G. PMID: 21596068.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    53. Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells. Pancreas. 2011 Apr; 40(3):453-9. Takahashi H, Li A, Dawson DW, Hines OJ, Reber HA, Eibl G. PMID: 21343834.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    54. Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer. Am J Pathol. 2011 Mar; 178(3):1340-9. Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ. PMID: 21356384.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    55. CXCR2-Dependent Endothelial Progenitor Cell Mobilization in Pancreatic Cancer Growth. Transl Oncol. 2011 Feb 01; 4(1):20-8. Li A, Cheng XJ, Moro A, Singh RK, Hines OJ, Eibl G. PMID: 21286374.
      View in: PubMed   Mentions:
    56. N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Surgery. 2011 May; 149(5):614-24. Angst E, Dawson DW, Stroka D, Gloor B, Park J, Candinas D, Reber HA, Hines OJ, Eibl G. PMID: 21236457.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    57. Bioluminescence imaging of angiogenesis in a murine orthotopic pancreatic cancer model. Mol Imaging Biol. 2010 Dec; 12(6):570-5. Angst E, Chen M, Mojadidi M, Hines OJ, Reber HA, Eibl G. PMID: 20376570.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    58. Cystic neoplasms of the pancreas: results of 114 cases. Pancreas. 2010 Nov; 39(8):1271-6. Donahue TR, Hines OJ, Farrell JJ, Tomlinson JS, Eibl G, Reber HA. PMID: 20717069.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    59. Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. Pancreas. 2010 Jul; 39(5):675-9. Angst E, Dawson DW, Nguyen A, Park J, Go VL, Reber HA, Hines OJ, Eibl G. PMID: 20173668.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    60. Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts. J Agric Food Chem. 2010 Jun 23; 58(12):7252-7. Zhang L, Angst E, Park JL, Moro A, Dawson DW, Reber HA, Eibl G, Hines OJ, Go VL, Lu QY. PMID: 20499918.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    61. Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. Pancreas. 2010 Apr; 39(3):332-9. Pham H, Chen M, Li A, King J, Angst E, Dawson DW, Park J, Reber HA, Hines OJ, Eibl G. PMID: 19820419.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    62. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G63-73. Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA, Yokosuka O, Pandol SJ, Gukovskaya AS. PMID: 19762431.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    63. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Res. 2009 Aug 15; 69(16):6539-45. Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. PMID: 19679549.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    64. Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. PLoS One. 2009 Jun 11; 4(6):e5875. Gao K, Zhou H, Zhang L, Lee JW, Zhou Q, Hu S, Wolinsky LE, Farrell J, Eibl G, Wong DT. PMID: 19517020.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    65. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas. 2008 Aug; 37(2):121-7. Hasan S, Satake M, Dawson DW, Funahashi H, Angst E, Go VL, Reber HA, Hines OJ, Eibl G. PMID: 18665070.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    66. Distal pancreatectomy: incidence of postoperative diabetes. J Gastrointest Surg. 2008 Sep; 12(9):1548-53. King J, Kazanjian K, Matsumoto J, Reber HA, Yeh MW, Hines OJ, Eibl G. PMID: 18543045.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    67. Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery. 2008 Jul; 144(1):57-65. Angst E, Reber HA, Hines OJ, Eibl G. PMID: 18571585.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    68. 15-Hydroxyprostaglandin dehydrogenase suppresses K-RasV12-dependent tumor formation in Nu/Nu mice. Mol Carcinog. 2008 Jun; 47(6):466-77. Pham H, Eibl G, Vincenti R, Chong B, Tai HH, Slice LW. PMID: 18058808.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    69. Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth. Pancreas. 2008 May; 36(4):353-62. Funahashi H, Satake M, Hasan S, Sawai H, Newman RA, Reber HA, Hines OJ, Eibl G. PMID: 18437081.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    70. The Role of PPAR-gamma and Its Interaction with COX-2 in Pancreatic Cancer. PPAR Res. 2008; 2008:326915. Eibl G. PMID: 18615182.
      View in: PubMed   Mentions:
    71. Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. Cancer Res. 2007 Aug 01; 67(15):7068-71. Funahashi H, Satake M, Dawson D, Huynh NA, Reber HA, Hines OJ, Eibl G. PMID: 17652141.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    72. Estrogen receptors in pancreatic tumors. Pancreas. 2006 Aug; 33(2):119-27. Satake M, Sawai H, Go VL, Satake K, Reber HA, Hines OJ, Eibl G. PMID: 16868476.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    73. Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system. Mol Cancer Res. 2006 Mar; 4(3):159-67. Sawai H, Liu J, Reber HA, Hines OJ, Eibl G. PMID: 16547153.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    74. Arsenite pre-conditioning reduces UVB-induced apoptosis in corneal epithelial cells through the anti-apoptotic activity of 27 kDa heat shock protein (HSP27). J Cell Physiol. 2006 Feb; 206(2):301-8. Shi B, Isseroff RR. PMID: 16142331.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    75. The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling. Cancer Res. 2005 Dec 15; 65(24):11536-44. Sawai H, Okada Y, Kazanjian K, Kim J, Hasan S, Hines OJ, Reber HA, Hoon DS, Eibl G. PMID: 16357163.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    76. The proteasome inhibitor MG132 induces apoptosis in human pancreatic cancer cells. Oncol Rep. 2005 Dec; 14(6):1635-8. Wente MN, Eibl G, Reber HA, Friess H, Büchler MW, Hines OJ. PMID: 16273269.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    77. A xenograft nude mouse model for perineural invasion and recurrence in pancreatic cancer. Pancreas. 2005 Oct; 31(3):258-62. Eibl G, Reber HA. PMID: 16163058.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    78. Management of pancreatic fistulas after pancreaticoduodenectomy: results in 437 consecutive patients. Arch Surg. 2005 Sep; 140(9):849-54; discussion 854-6. Kazanjian KK, Hines OJ, Eibl G, Reber HA. PMID: 16172293.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    79. Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer. Cancer Res. 2005 Apr 01; 65(7):2738-45. Guha S, Eibl G, Kisfalvi K, Fan RS, Burdick M, Reber H, Hines OJ, Strieter R, Rozengurt E. PMID: 15805273.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    80. Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor. Cancer Res. 2005 Feb 01; 65(3):982-90. Eibl G, Takata Y, Boros LG, Liu J, Okada Y, Reber HA, Hines OJ. PMID: 15705899.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    81. COX and PPAR: possible interactions in pancreatic cancer. Pancreas. 2004 Nov; 29(4):247-53. Eibl G, Reber HA, Hines OJ, Go VL. PMID: 15502639.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    82. Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells. Clin Exp Metastasis. 2004; 21(4):285-92. Okada Y, Eibl G, Guha S, Duffy JP, Reber HA, Hines OJ. PMID: 15554384.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    83. Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer. Surgery. 2003 Aug; 134(2):293-9. Okada Y, Eibl G, Duffy JP, Reber HA, Hines OJ. PMID: 12947332.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    84. PGE(2) is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells. Biochem Biophys Res Commun. 2003 Jul 11; 306(4):887-97. Eibl G, Bruemmer D, Okada Y, Duffy JP, Law RE, Reber HA, Hines OJ. PMID: 12821125.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    85. Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer. Mol Cancer. 2003 Jan 22; 2:12. Duffy JP, Eibl G, Reber HA, Hines OJ. PMID: 12605718.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    86. The selective cyclooxygenase-2 inhibitor nimesulide induces apoptosis in pancreatic cancer cells independent of COX-2. Pancreas. 2003 Jan; 26(1):33-41. Eibl G, Reber HA, Wente MN, Hines OJ. PMID: 12499915.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    87. Omega-3 fatty acid supplementation increases anti-inflammatory cytokines and attenuates systemic disease sequelae in experimental pancreatitis. JPEN J Parenter Enteral Nutr. 2002 Nov-Dec; 26(6):351-6. Foitzik T, Eibl G, Schneider P, Wenger FA, Jacobi CA, Buhr HJ. PMID: 12405646.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    88. Endothelin A but not endothelin B receptor blockade reduces capillary permeability in severe experimental pancreatitis. Pancreas. 2002 Aug; 25(2):e15-20. Eibl G, Forgacs B, Hotz HG, Buhr HJ, Foitzik T. PMID: 12142750.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    89. Therapy of microcirculatory disorders in severe acute pancreatitis: what mediators should we block? Intensive Care Med. 2002 Feb; 28(2):139-46. Eibl G, Buhr HJ, Foitzik T. PMID: 11907656.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
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