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James T Niemann

Title(s)Professor-in-Residence, Emergency Medicine
SchoolMedicine
Phone(310) 222-3508
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    Collapse Research 
    Collapse Research Activities and Funding
    Ischemic Arrest, Cytokines, and Organ Dysfunction
    NIH/NHLBI R01HL076671Jun 1, 2005 - Apr 30, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bosson N, Fang A, Kaji AH, Gausche-Hill M, French WJ, Shavelle D, Thomas JL, Niemann JT. Racial and ethnic differences in outcomes after out-of-hospital cardiac arrest: Hispanics and Blacks may fare worse than non-Hispanic Whites. Resuscitation. 2019 04; 137:29-34. PMID: 30753852.
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    2. Bosson N, Isakson B, Morgan JA, Kaji AH, Uner A, Hurley K, Henry TD, Niemann JT. Safety and Effectiveness of Field Nitroglycerin in Patients with Suspected ST Elevation Myocardial Infarction. Prehosp Emerg Care. 2019 Sep-Oct; 23(5):603-611. PMID: 30556765.
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    3. D'Arcy NT, Bosson N, Kaji AH, Bui QT, French WJ, Thomas JL, Elizarraraz Y, Gonzalez N, Garcia J, Niemann JT. Weekly Checks Improve Real-Time Prehospital ECG Transmission in Suspected STEMI. Prehosp Disaster Med. 2018 Jun; 33(3):245-249. PMID: 29708085.
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    4. Bosson N, Baruch T, French WJ, Fang A, Kaji AH, Gausche-Hill M, Rock A, Shavelle D, Thomas JL, Niemann JT. Regional "Call 911" Emergency Department Protocol to Reduce Interfacility Transfer Delay for Patients With ST-Segment-Elevation Myocardial Infarction. J Am Heart Assoc. 2017 12 23; 6(12). PMID: 29275369.
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    5. Shavelle DM, Bosson N, Thomas JL, Kaji AH, Sung G, French WJ, Niemann JT. Outcomes of ST Elevation Myocardial Infarction Complicated by Out-of-Hospital Cardiac Arrest (from the Los Angeles County Regional System). Am J Cardiol. 2017 Sep 01; 120(5):729-733. PMID: 28728743.
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    6. Bosson N, Sanko S, Stickney RE, Niemann J, French WJ, Jollis JG, Kontos MC, Taylor TG, Macfarlane PW, Tadeo R, Koenig W, Eckstein M. Causes of Prehospital Misinterpretations of ST Elevation Myocardial Infarction. Prehosp Emerg Care. 2017 May-Jun; 21(3):283-290. PMID: 27858506.
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    7. Bosson N, Kaji AH, Fang A, Thomas JL, French WJ, Shavelle D, Niemann JT. Sex Differences in Survival From Out-of-Hospital Cardiac Arrest in the Era of Regionalized Systems and Advanced Post-Resuscitation Care. J Am Heart Assoc. 2016 09 15; 5(9). PMID: 27633392.
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    8. Youngquist ST, Shah AP, Rosborough JP, Niemann JT. High Serum Tumor Necrosis Factor Levels in the Early Post-Cardiac Arrest Period Are Associated with Poor Short-Term Survival in a Swine Model of Ventricular Fibrillation. J Interferon Cytokine Res. 2016 10; 36(10):575-579. PMID: 27607559.
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    9. Niemann JT, Lewis RJ. The Resuscitative Power of a Telephone Call. JAMA Cardiol. 2016 06 01; 1(3):302-4. PMID: 27438109.
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    10. Bosson NE, Kaji AH, Koenig WJ, Niemann JT. Effect of Therapeutic Hypothermia on Survival and Neurologic Outcome in the Elderly. Ther Hypothermia Temp Manag. 2016 Jun; 6(2):71-5. PMID: 26866849.
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    11. Sung G, Bosson N, Kaji AH, Eckstein M, Shavelle D, French WJ, Thomas JL, Koenig W, Niemann JT. Therapeutic Hypothermia After Resuscitation From a Non-Shockable Rhythm Improves Outcomes in a Regionalized System of Cardiac Arrest Care. Neurocrit Care. 2016 Feb; 24(1):90-6. PMID: 26264064.
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    12. Bosson N, Kaji AH, Niemann JT, Squire B, Eckstein M, French WJ, Rashi P, Tadeo R, Koenig W. The Utility of Prehospital ECG Transmission in a Large EMS System. Prehosp Emerg Care. 2015; 19(4):496-503. PMID: 25901583.
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    13. Kaji AH, Hanif AM, Bosson N, Ostermayer D, Niemann JT. Predictors of neurologic outcome in patients resuscitated from out-of-hospital cardiac arrest using classification and regression tree analysis. Am J Cardiol. 2014 Oct 01; 114(7):1024-8. PMID: 25118118.
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    14. Thomas JL, Bosson N, Kaji AH, Ji Y, Sung G, Shavelle DM, French WJ, Koenig W, Niemann JT. Treatment and outcomes of ST segment elevation myocardial infarction and out-of-hospital cardiac arrest in a regionalized system of care based on presence or absence of initial shockable cardiac arrest rhythm. Am J Cardiol. 2014 Oct 01; 114(7):968-71. PMID: 25118120.
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    15. Bosson N, Kaji AH, Koenig W, Rashi P, Tadeo R, Gorospe D, Niemann JT. Re-examining outcomes after unsuccessful out-of-hospital resuscitation in the era of field termination of resuscitation guidelines and regionalized post-resuscitation care. Resuscitation. 2014 Jul; 85(7):915-9. PMID: 24735728.
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    16. Bosson N, Kaji AH, Niemann JT, Eckstein M, Rashi P, Tadeo R, Gorospe D, Sung G, French WJ, Shavelle D, Thomas JL, Koenig W. Survival and neurologic outcome after out-of-hospital cardiac arrest: results one year after regionalization of post-cardiac arrest care in a large metropolitan area. Prehosp Emerg Care. 2014 Apr-Jun; 18(2):217-23. PMID: 24401209.
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    17. Squire BT, Tamayo-Sarver JH, Rashi P, Koenig W, Niemann JT. Effect of prehospital cardiac catheterization lab activation on door-to-balloon time, mortality, and false-positive activation. Prehosp Emerg Care. 2014 Jan-Mar; 18(1):1-8. PMID: 24329031.
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    18. Myerburg RJ, Halperin H, Egan DA, Boineau R, Chugh SS, Gillis AM, Goldhaber JI, Lathrop DA, Liu P, Niemann JT, Ornato JP, Sopko G, Van Eyk JE, Walcott GP, Weisfeldt ML, Wright JD, Zipes DP. Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop. Circulation. 2013 Dec 03; 128(23):2532-41. PMID: 24297818.
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    19. Youngquist ST, Niemann JT, Shah AP, Thomas JL, Rosborough JP. Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-a levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. J Interferon Cytokine Res. 2013 Jun; 33(6):292-6. PMID: 23659671.
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    20. Niemann JT. Is there life after hospital discharge for resuscitated cardiac arrest patients? Crit Care Med. 2013 May; 41(5):1372-3. PMID: 23591219.
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    21. Youngquist ST, Niemann JT, Shah AP, Thomas JL, Rosborough JP. A comparison of etanercept vs. infliximab for the treatment of post-arrest myocardial dysfunction in a swine model of ventricular fibrillation. Resuscitation. 2013 Jul; 84(7):999-1003. PMID: 23313857.
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    22. Niemann JT, Youngquist ST, Shah AP, Thomas JL, Rosborough JP. TNF-a blockade improves early post-resuscitation survival and hemodynamics in a swine model of ischemic ventricular fibrillation. Resuscitation. 2013 Jan; 84(1):103-7. PMID: 22683946.
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    23. Azadi N, Niemann JT, Thomas JL. Coronary imaging and intervention during cardiovascular collapse: use of the LUCAS mechanical CPR device in the cardiac catheterization laboratory. J Invasive Cardiol. 2012 Feb; 24(2):79-83. PMID: 22294540.
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    24. Youngquist ST, Niemann JT. Regarding "Effect of adrenaline on survival in out-of-hospital cardiac arrest: A randomised double-blind placebo-controlled trial". Resuscitation. 2012 Apr; 83(4):e105; author reply e107. PMID: 22266068.
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    25. Niemann JT. Sodium nitroprusside-enhanced cardiopulmonary resuscitation: are we out of the box yet? Crit Care Med. 2011 Dec; 39(12):2775-6. PMID: 22094513.
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    26. Sherman L, Niemann J, Youngquist ST, Shah AP, Rosborough JP. Beta-blockade causes a reduction in the frequency spectrum of VF but improves resuscitation outcome: A potential limitation of quantitative waveform measures. Resuscitation. 2012 Apr; 83(4):511-6. PMID: 21996018.
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    27. Kaji AH, Hanif AM, Thomas JL, Niemann JT. Out-of-hospital cardiac arrest: early in-hospital hypotension versus out-of-hospital factors in predicting in-hospital mortality among those surviving to hospital admission. Resuscitation. 2011 Oct; 82(10):1314-7. PMID: 21723027.
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    28. Shah AP, Youngquist ST, McClung CD, Thomas JL, Tzvetkova E, Hanif MA, Rosborough JP, Niemann JT. Endothelin-1 attenuates the hemodynamic response to exogenous epinephrine in a porcine ischemic ventricular fibrillation cardiac arrest model. J Interferon Cytokine Res. 2011 Sep; 31(9):679-84. PMID: 21651344.
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    29. Niemann JT, Youngquist S, Rosborough JP. Does early postresuscitation stress hyperglycemia affect 72-hour neurologic outcome? Preliminary observations in the Swine model. Prehosp Emerg Care. 2011 Jul-Sep; 15(3):405-9. PMID: 21480776.
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    30. Shah AP, Youngquist ST, McClung CD, Tzvetkova E, Hanif MA, Rosborough JP, Niemann JT. Markers of progenitor cell recruitment and differentiation rise early during ischemia and continue during resuscitation in a porcine acute ischemia model. J Interferon Cytokine Res. 2011 Jun; 31(6):509-13. PMID: 21332365.
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    31. Niemann JT. Quantitative measures of the ventricular fibrillation waveform and resuscitation outcome. Crit Care Med. 2010 Dec; 38(12):2416-7. PMID: 21088511.
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    32. Youngquist ST, Shah A, McClung C, Thomas JL, Rosborough JP, Niemann JT. Does prearrest adrenergic integrity affect pressor response? A comparison of epinephrine and vasopressin in a spontaneous ventricular fibrillation swine model. Resuscitation. 2011 Feb; 82(2):228-31. PMID: 21051132.
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    33. Kaji AH, Hanif AM, Niemann JT. Advanced rescuer- versus citizen-witnessed cardiac arrest: Is there a difference in outcome? Prehosp Emerg Care. 2011 Jan-Mar; 15(1):55-60. PMID: 20836699.
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    34. Hanif MA, Kaji AH, Niemann JT. Advanced airway management does not improve outcome of out-of-hospital cardiac arrest. Acad Emerg Med. 2010 Sep; 17(9):926-31. PMID: 20836772.
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    35. Youngquist ST, Niemann JT, Allread WG, Heyming T, Rosborough JP. Neurologically intact survival in a porcine model of cardiac arrest: manual cardiopulmonary resuscitation vs. LifeBelt cardiopulmonary resuscitation. Prehosp Emerg Care. 2010 Jul-Sep; 14(3):324-8. PMID: 20388031.
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    36. Niemann JT, Youngquist S, Rosborough JP, Shah AP, Phan QT, Filler SG. Infliximab attenuates early myocardial dysfunction after resuscitation in a swine cardiac arrest model. Crit Care Med. 2010 Apr; 38(4):1162-7. PMID: 20154606.
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    37. Niemann JT, Rosborough JP, Youngquist ST, Shah AP. Transthoracic defibrillation potential gradients in a closed chest porcine model of prolonged spontaneous and electrically induced ventricular fibrillation. Resuscitation. 2010 Apr; 81(4):477-80. PMID: 20122785.
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    38. Youngquist ST, Heyming T, Rosborough JP, Niemann JT. Hypocalcemia following resuscitation from cardiac arrest revisited. Resuscitation. 2010 Jan; 81(1):117-22. PMID: 19913975.
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    39. Niemann JT, Rosborough JP, Youngquist S, Shah AP, Lewis RJ, Phan QT, Filler SG. Cardiac function and the proinflammatory cytokine response after recovery from cardiac arrest in swine. J Interferon Cytokine Res. 2009 Nov; 29(11):749-58. PMID: 19642909.
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    40. Shah AP, Niemann JT, Youngquist S, Heyming T, Rosborough JP. Plasma endothelin-1 level at the onset of ischemic ventricular fibrillation predicts resuscitation outcome. Resuscitation. 2009 May; 80(5):580-3. PMID: 19362407.
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    41. Shah AP, Niemann JT, Youngquist S, Josephson G, Rosborough JP. Endothelin-1 is not predictive of ventricular ectopy or ventricular fibrillation during acute myocardial ischemia. J Interferon Cytokine Res. 2008 Nov; 28(11):639-41. PMID: 18844577.
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    42. Youngquist ST, Niemann JT, Heyming TW, Rosborough JP. The central nervous system cytokine response to global ischemia following resuscitation from ventricular fibrillation in a porcine model. Resuscitation. 2009 Feb; 80(2):249-52. PMID: 18954931.
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    43. Niemann JT, Rosborough J, Youngquist S, Lewis RJ, Phan QT, Filler S. The proinflammatory cytokine response following resuscitation in the swine model depends on the method of ventricular fibrillation induction. Acad Emerg Med. 2008 Oct; 15(10):939-44. PMID: 18785945.
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    44. Kaji AH, Koenig W, Eckstein M, Youngquist S, Tadeo R, Niemann JT. The need for uniform definitions in the regionalized care of ST-segment elevation myocardial infarction. Acad Emerg Med. 2008 Aug; 15(8):759-61. PMID: 18627583.
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    45. Youngquist ST, Shah AP, Niemann JT, Kaji AH, French WJ. A comparison of door-to-balloon times and false-positive activations between emergency department and out-of-hospital activation of the coronary catheterization team. Acad Emerg Med. 2008 Aug; 15(8):784-7. PMID: 18638030.
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    46. Menegazzi JJ, Hsieh M, Niemann JT, Swor RA. Derivation of clinical predictors of failed rescue shock during out-of-hospital ventricular fibrillation. Prehosp Emerg Care. 2008 Jul-Sep; 12(3):347-51. PMID: 18584503.
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    47. Niemann JT, Rosborough JP, Youngquist S. Is the tumour necrosis factor-alpha response following resuscitation gender dependent in the swine model? Resuscitation. 2008 May; 77(2):258-63. PMID: 18304717.
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    48. Youngquist ST, Kaji AH, Lipsky AM, Koenig WJ, Niemann JT. A Bayesian sensitivity analysis of out-of-hospital 12-lead electrocardiograms: implications for regionalization of cardiac care. Acad Emerg Med. 2007 Dec; 14(12):1165-71. PMID: 18045892.
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    49. Youngquist ST, Kaji AH, Niemann JT. Beta-blocker use and the changing epidemiology of out-of-hospital cardiac arrest rhythms. Resuscitation. 2008 Mar; 76(3):376-80. PMID: 17976890.
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    50. Sherman LD, Niemann JT, Rosborough JP, Menegazzi JJ. The effect of ischemia on ventricular fibrillation as measured by fractal dimension and frequency measures. Resuscitation. 2007 Dec; 75(3):499-505. PMID: 17630089.
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    51. Niemann JT, Rosborough JP, Youngquist S, Thomas J, Lewis RJ. Is all ventricular fibrillation the same? A comparison of ischemically induced with electrically induced ventricular fibrillation in a porcine cardiac arrest and resuscitation model. Crit Care Med. 2007 May; 35(5):1356-61. PMID: 17414084.
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    52. Rosborough JP, Deno DC, Walker RG, Niemann JT. A percutaneous catheter-based system for the measurement of potential gradients applicable to the study of transthoracic defibrillation. Pacing Clin Electrophysiol. 2007 Feb; 30(2):166-74. PMID: 17338711.
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    53. Lewis RJ, Niemann JT. Manual vs device-assisted CPR: reconciling apparently contradictory results. JAMA. 2006 Jun 14; 295(22):2661-4. PMID: 16772632.
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    54. Niemann JT, Rosborough JP, Kassabian L, Salami B. A new device producing manual sternal compression with thoracic constraint for cardiopulmonary resuscitation. Resuscitation. 2006 May; 69(2):295-301. PMID: 16457933.
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    55. Niemann JT, Garner D. Post-resuscitation plasma catecholamines after prolonged arrest in a swine model. Resuscitation. 2005 Apr; 65(1):97-101. PMID: 15797281.
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    56. Niemann JT, Walker RG, Rosborough JP. Intracardiac voltage gradients during transthoracic defibrillation: implications for postshock myocardial injury. Acad Emerg Med. 2005 Feb; 12(2):99-105. PMID: 15692128.
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    57. Haukoos JS, Lewis RJ, Niemann JT. Prediction rules for estimating neurologic outcome following out-of-hospital cardiac arrest. Resuscitation. 2004 Nov; 63(2):145-55. PMID: 15531065.
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    58. Niemann JT, Garner D, Lewis RJ. Tumor necrosis factor-alpha is associated with early postresuscitation myocardial dysfunction. Crit Care Med. 2004 Aug; 32(8):1753-8. PMID: 15286554.
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    59. Niemann JT, Rosborough JP, Walker RG. A model of ischemically induced ventricular fibrillation for comparison of fixed-dose and escalating-dose defibrillation strategies. Acad Emerg Med. 2004 Jun; 11(6):619-24. PMID: 15175198.
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    60. Niemann JT, Garner D, Khaleeli E, Lewis RJ. Milrinone facilitates resuscitation from cardiac arrest and attenuates postresuscitation myocardial dysfunction. Circulation. 2003 Dec 16; 108(24):3031-5. PMID: 14638547.
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    61. Haukoos JS, Lewis RJ, Stratton SJ, Niemann JT. Is the ACLS score a valid prediction rule for survival after cardiac arrest? Acad Emerg Med. 2003 Jun; 10(6):621-6. PMID: 12782522.
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    62. Niemann JT, Garner D, Lewis RJ. Left ventricular function after monophasic and biphasic waveform defibrillation: the impact of cardiopulmonary resuscitation time on contractile indices. Acad Emerg Med. 2003 Jan; 10(1):9-15. PMID: 12511308.
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    63. Niemann JT, Garner D, Lewis RJ. Transthoracic impedance does not decrease with rapidly repeated countershocks in a swine cardiac arrest model. Resuscitation. 2003 Jan; 56(1):91-5. PMID: 12505744.
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    64. Niemann JT. Vasopressin in piglet "pediatric models" of cardiac arrest. Crit Care Med. 2002 May; 30(5):1158-9. PMID: 12006820.
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    65. Niemann JT, Stratton SJ, Cruz B, Lewis RJ. Endotracheal drug administration during out-of-hospital resuscitation: where are the survivors? Resuscitation. 2002 May; 53(2):153-7. PMID: 12009218.
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    66. Stratton SJ, Niemann JT. Reconsideration of proximate Utstein-style end points. Crit Care Med. 2002 Apr; 30(4 Suppl):S137-9. PMID: 11940788.
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    67. Niemann JT, Stratton SJ. The Utstein template and the effect of in-hospital decisions: the impact of do-not-attempt resuscitation status on survival to discharge statistics. Resuscitation. 2001 Dec; 51(3):233-7. PMID: 11738772.
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    68. Niemann JT, Burian D, Garner D, Lewis RJ. Monophasic versus biphasic transthoracic countershock after prolonged ventricular fibrillation in a swine model. J Am Coll Cardiol. 2000 Sep; 36(3):932-8. PMID: 10987622.
      View in: PubMed
    69. Niemann JT, Burian D, Garner D, Lewis RJ. Transthoracic monophasic and biphasic defibrillation in a swine model: a comparison of efficacy, ST segment changes, and postshock hemodynamics. Resuscitation. 2000 Sep; 47(1):51-8. PMID: 11004381.
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