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Jeffrey Laurence Ardell

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
Address760 Westwood Plaza 76-143
Los Angeles CA 90024
Phone50417
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    Other Positions
    Title(s)Professor-in-Residence, Anesthesiology


    Collapse Research 
    Collapse Research Activities and Funding
    Spinal Neuraxial Modulatin of Ventricular Excitability - Mechanisms and Therapeutics
    NIH/NHLBI R01HL136836Aug 2, 2018 - Jul 31, 2022
    Role: Co-Principal Investigator
    Bioelectric monitoring and control of the heart
    NIH/NIBIB U01EB025138Sep 26, 2017 - Jun 30, 2021
    Role: Principal Investigator
    Distributed electrode system for high-fidelity cardio-neural mapping
    NIH/NIBIB U18EB021799Sep 1, 2017 - Jul 31, 2018
    Role: Principal Investigator
    Myocardial ischemia remodels the cardiac nervous system
    NIH/NHLBI R01HL071830Apr 5, 2005 - Mar 31, 2014
    Role: Principal Investigator
    INTRINSIC CARDIAC NEURONS AND CARDIAC CONTROL
    NIH/NHLBI R01HL058140Apr 1, 1997 - Mar 31, 2003
    Role: Principal Investigator
    REFLEX CONTROL OF CIRCULATION DURING EXERCISE
    NIH/NHLBI R23HL032392Jul 1, 1984 - Jun 30, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Long-term Follow-Up of Patients with Heart Failure and Reduced Ejection Fraction Receiving Autonomic Regulation Therapy in the ANTHEM-HF Pilot Study. Int J Cardiol. 2020 Oct 07. Sharma K, Premchand RK, Mittal S, Monteiro R, Libbus I, DiCarlo LA, Ardell JL, Amurthur B, KenKnight BH, Anand IS. PMID: 33038408.
      View in: PubMed   Mentions:    Fields:    
    2. Mechanism of Ventricular Premature Beats Elicited by Left Stellate Ganglion Stimulation During Acute Ischemia of the Anterior Left Ventricle. Cardiovasc Res. 2020 Aug 27. Boukens BJD, Dacey M, Meijborg VMF, Janse MJ, Hadaya J, Hanna P, Swid MA, Opthof T, Ardell J, Shivkumar K, Coronel R. PMID: 32853334.
      View in: PubMed   Mentions:    Fields:    
    3. Baseline NT-proBNP and responsiveness to autonomic regulation therapy in patients with heart failure and reduced ejection fraction. Int J Cardiol Heart Vasc. 2020 Aug; 29:100520. Anand I, Ardell JL, Gregory D, Libbus I, DiCarlo L, Premchand RK, Sharma K, Mittal S, Monteiro R. PMID: 32509959.
      View in: PubMed   Mentions:
    4. Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart. . 2020 05 01; 318(5):H1091-H1099. Chan SA, Vaseghi M, Kluge N, Shivkumar K, Ardell JL, Smith C. PMID: 32216617.
      View in: PubMed   Mentions:
    5. Spinal cord neural network interactions: implications for sympathetic control of the porcine heart. . 2020 04 01; 318(4):H830-H839. Dale EA, Kipke J, Kubo Y, Sunshine MD, Castro PA, Ardell JL, Mahajan A. PMID: 32108524.
      View in: PubMed   Mentions:
    6. Comparison of symptomatic and functional responses to vagus nerve stimulation in ANTHEM-HF, INOVATE-HF, and NECTAR-HF. ESC Heart Fail. 2020 02; 7(1):75-83. Anand IS, Konstam MA, Klein HU, Mann DL, Ardell JL, Gregory DD, Massaro JM, Libbus I, DiCarlo LA, Udelson JJE, Butler J, Parker JD, Teerlink JR. PMID: 31984682.
      View in: PubMed   Mentions: 3     Fields:    
    7. Stellate ganglion stimulation causes spatiotemporal changes in ventricular repolarization in pig. Heart Rhythm. 2020 May; 17(5 Pt A):795-803. Meijborg VMF, Boukens BJD, Janse MJ, Salavatian S, Dacey MJ, Yoshie K, Opthof T, Swid MA, Hoang JD, Hanna P, Ardell J, Shivkumar K, Coronel R. PMID: 31917369.
      View in: PubMed   Mentions:    Fields:    
    8. Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation. JCI Insight. 2019 12 05; 4(23). Ardell JL, Foreman RD, Armour JA, Shivkumar K. PMID: 31671074.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. Impact of Autonomic Regulation Therapy in Patients with Heart Failure: ANTHEM-HFrEF Pivotal Study Design. Circ Heart Fail. 2019 11; 12(11):e005879. Konstam MA, Udelson JE, Butler J, Klein HU, Parker JD, Teerlink JR, Wedge PM, Saville BR, Ardell JL, Libbus I, DiCarlo LA. PMID: 31722536.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    10. Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation. . 2019 12 01; 317(6):H1328-H1341. Jungen C, Scherschel K, Flenner F, Jee H, Rajendran P, De Jong KA, Nikolaev V, Meyer C, Ardell JL, Tompkins JD. PMID: 31625779.
      View in: PubMed   Mentions:
    11. Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle. . 2019 11 01; 317(5):H1134-H1141. Salavatian S, Ardell SM, Hammer M, Gibbons D, Armour JA, Ardell JL. PMID: 31538809.
      View in: PubMed   Mentions:
    12. Background pharmacological therapy in the ANTHEM-HF: comparison to contemporary trials of novel heart failure therapies. ESC Heart Fail. 2019 10; 6(5):1052-1056. Premchand RK, Sharma K, Mittal S, Monteiro R, Libbus I, Ardell JL, Gregory DD, KenKnight BH, Amurthur B, DiCarlo LA, Anand IS. PMID: 31339232.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    13. Premature ventricular contractions activate vagal afferents and alter autonomic tone: implications for premature ventricular contraction-induced cardiomyopathy. . 2019 09 01; 317(3):H607-H616. Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Ardell JL, Armour JA, Vaseghi M. PMID: 31322427.
      View in: PubMed   Mentions:
    14. Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Nat Commun. 2019 04 26; 10(1):1944. Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K. PMID: 31028266.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Electroceutical Targeting of the Autonomic Nervous System. Physiology (Bethesda). 2019 03 01; 34(2):150-162. Horn CC, Ardell JL, Fisher LE. PMID: 30724129.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    16. Calming the Nervous Heart: Autonomic Therapies in Heart Failure. Card Fail Rev. 2018 Aug; 4(2):92-98. Hanna P, Shivkumar K, Ardell JL. PMID: 30206483.
      View in: PubMed   Mentions:
    17. RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity. Sci Rep. 2018 06 05; 8(1):8633. Bardsley EN, Davis H, Ajijola OA, Buckler KJ, Ardell JL, Shivkumar K, Paterson DJ. PMID: 29872217.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity. JCI Insight. 2018 05 03; 3(9). Liu K, Li D, Hao G, McCaffary D, Neely O, Woodward L, Ioannides D, Lu CJ, Brescia M, Zaccolo M, Tandri H, Ajijola OA, Ardell JL, Shivkumar K, Paterson DJ. PMID: 29720569.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    19. Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. . 2018 05 01; 314(5):H954-H966. Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA. PMID: 29351450.
      View in: PubMed   Mentions:
    20. Autonomic regulation therapy to enhance myocardial function in heart failure patients: the ANTHEM-HFpEF study. ESC Heart Fail. 2018 02; 5(1):95-100. DiCarlo LA, Libbus I, Kumar HU, Mittal S, Premchand RK, Amurthur B, KenKnight BH, Ardell JL, Anand IS. PMID: 29283224.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Defining the neural fulcrum for chronic vagus nerve stimulation: implications for integrated cardiac control. J Physiol. 2017 11 15; 595(22):6887-6903. Ardell JL, Nier H, Hammer M, Southerland EM, Ardell CL, Beaumont E, KenKnight BH, Armour JA. PMID: 28862330.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    22. Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm. JCI Insight. 2017 09 21; 2(18). Ajijola OA, Hoover DB, Simerly TM, Brown TC, Yanagawa J, Biniwale RM, Lee JM, Sadeghi A, Khanlou N, Ardell JL, Shivkumar K. PMID: 28931760.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    23. Vagal Neuromodulation for Atrial Arrhythmias. JACC Clin Electrophysiol. 2017 09; 3(9):939-941. Shivkumar K, Ardell JL. PMID: 29759718.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Thoracic spinal cord and cervical vagosympathetic neuromodulation obtund nodose sensory transduction of myocardial ischemia. Auton Neurosci. 2017 12; 208:57-65. Salavatian S, Beaumont E, Gibbons D, Hammer M, Hoover DB, Armour JA, Ardell JL. PMID: 28919363.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Recurrent myocardial infarction: Mechanisms of free-floating adaptation and autonomic derangement in networked cardiac neural control. PLoS One. 2017; 12(7):e0180194. Kember G, Ardell JL, Shivkumar K, Armour JA. PMID: 28692680.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. Bioelectronic block of paravertebral sympathetic nerves mitigates post-myocardial infarction ventricular arrhythmias. Heart Rhythm. 2017 11; 14(11):1665-1672. Chui RW, Buckley U, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL. PMID: 28629852.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    27. Sympathetic neural recording-It is all in the details. Heart Rhythm. 2017 07; 14(7):972-973. Ardell JL, Shivkumar K. PMID: 28438720.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping. Circ Arrhythm Electrophysiol. 2017 Apr; 10(4). Hamon D, Rajendran PS, Chui RW, Ajijola OA, Irie T, Talebi R, Salavatian S, Vaseghi M, Bradfield JS, Armour JA, Ardell JL, Shivkumar K. PMID: 28408652.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    29. Bioelectronic neuromodulation of the paravertebral cardiac efferent sympathetic outflow and its effect on ventricular electrical indices. Heart Rhythm. 2017 07; 14(7):1063-1070. Buckley U, Chui RW, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL. PMID: 28219848.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    30. Sympathetic modulation of electrical activation in normal and infarcted myocardium: implications for arrhythmogenesis. . 2017 Mar 01; 312(3):H608-H621. Ajijola OA, Lux RL, Khahera A, Kwon O, Aliotta E, Ennis DB, Fishbein MC, Ardell JL, Shivkumar K. PMID: 28087519.
      View in: PubMed   Mentions:
    31. Neurocardiology: Structure-Based Function. Compr Physiol. 2016 09 15; 6(4):1635-1653. Ardell JL, Armour JA. PMID: 27783854.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    32. Vagal stimulation targets select populations of intrinsic cardiac neurons to control neurally induced atrial fibrillation. . 2016 11 01; 311(5):H1311-H1320. Salavatian S, Beaumont E, Longpré JP, Armour JA, Vinet A, Jacquemet V, Shivkumar K, Ardell JL. PMID: 27591222.
      View in: PubMed   Mentions:
    33. Cardiac autonomic control in health and disease. J Physiol. 2016 07 15; 594(14):3851-2. Shivkumar K, Ardell JL. PMID: 27417670.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Translational neurocardiology: preclinical models and cardioneural integrative aspects. J Physiol. 2016 07 15; 594(14):3877-909. Ardell JL, Andresen MC, Armour JA, Billman GE, Chen PS, Foreman RD, Herring N, O'Leary DS, Sabbah HN, Schultz HD, Sunagawa K, Zucker IH. PMID: 27098459.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    35. Pathological effects of chronic myocardial infarction on peripheral neurons mediating cardiac neurotransmission. Auton Neurosci. 2016 05; 197:34-40. Nakamura K, Ajijola OA, Aliotta E, Armour JA, Ardell JL, Shivkumar K. PMID: 27209472.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    36. Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig. . 2016 May 15; 310(10):H1349-59. Beaumont E, Wright GL, Southerland EM, Li Y, Chui R, KenKnight BH, Armour JA, Ardell JL. PMID: 26993230.
      View in: PubMed   Mentions:
    37. Heart failure: Mechanisms of spinal cord neuromodulation for heart disease. Nat Rev Cardiol. 2016 Mar; 13(3):127-8. Ardell JL. PMID: 26843288.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    38. Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system. J Physiol. 2016 Jan 15; 594(2):321-41. Rajendran PS, Nakamura K, Ajijola OA, Vaseghi M, Armour JA, Ardell JL, Shivkumar K. PMID: 26572244.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    39. Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology. . 2016 Mar 01; 310(5):R414-21. Yamakawa K, Howard-Quijano K, Zhou W, Rajendran P, Yagishita D, Vaseghi M, Ajijola OA, Armour JA, Shivkumar K, Ardell JL, Mahajan A. PMID: 26661096.
      View in: PubMed   Mentions:
    40. Extended Follow-Up of Patients With Heart Failure Receiving Autonomic Regulation Therapy in the ANTHEM-HF Study. J Card Fail. 2016 Aug; 22(8):639-42. Premchand RK, Sharma K, Mittal S, Monteiro R, Dixit S, Libbus I, DiCarlo LA, Ardell JL, Rector TS, Amurthur B, KenKnight BH, Anand IS. PMID: 26576716.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    41. Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function. . 2015 Nov 15; 309(10):H1740-52. Ardell JL, Rajendran PS, Nier HA, KenKnight BH, Armour JA. PMID: 26371171.
      View in: PubMed   Mentions:
    42. Vagus nerve stimulation mitigates intrinsic cardiac neuronal and adverse myocyte remodeling postmyocardial infarction. . 2015 Oct; 309(7):H1198-206. Beaumont E, Southerland EM, Hardwick JC, Wright GL, Ryan S, Li Y, KenKnight BH, Armour JA, Ardell JL. PMID: 26276818.
      View in: PubMed   Mentions:
    43. Targeted stellate decentralization: Implications for sympathetic control of ventricular electrophysiology. Heart Rhythm. 2016 Jan; 13(1):282-8. Buckley U, Yamakawa K, Takamiya T, Andrew Armour J, Shivkumar K, Ardell JL. PMID: 26282244.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    44. Autonomic Regulation Therapy in Heart Failure. Curr Heart Fail Rep. 2015 Aug; 12(4):284-93. Buckley U, Shivkumar K, Ardell JL. PMID: 26054327.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    45. Cardiac innervation and sudden cardiac death. Circ Res. 2015 Jun 05; 116(12):2005-19. Fukuda K, Kanazawa H, Aizawa Y, Ardell JL, Shivkumar K. PMID: 26044253.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimals
    46. Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus. . 2015 Jul 15; 309(2):R179-88. Hardwick JC, Ryan SE, Powers EN, Southerland EM, Ardell JL. PMID: 25947168.
      View in: PubMed   Mentions:
    47. Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: Neuropeptide and morphologic changes. Heart Rhythm. 2015 May; 12(5):1027-35. Ajijola OA, Yagishita D, Reddy NK, Yamakawa K, Vaseghi M, Downs AM, Hoover DB, Ardell JL, Shivkumar K. PMID: 25640636.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    48. Vagal nerve stimulation therapy: what is being stimulated? PLoS One. 2014; 9(12):e114498. Kember G, Ardell JL, Armour JA, Zamir M. PMID: 25479368.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    49. Chronic spinal cord stimulation modifies intrinsic cardiac synaptic efficacy in the suppression of atrial fibrillation. Auton Neurosci. 2014 Dec; 186:38-44. Ardell JL, Cardinal R, Beaumont E, Vermeulen M, Smith FM, Andrew Armour J. PMID: 25301713.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    50. Autonomic regulation therapy via left or right cervical vagus nerve stimulation in patients with chronic heart failure: results of the ANTHEM-HF trial. J Card Fail. 2014 Nov; 20(11):808-16. Premchand RK, Sharma K, Mittal S, Monteiro R, Dixit S, Libbus I, DiCarlo LA, Ardell JL, Rector TS, Amurthur B, KenKnight BH, Anand IS. PMID: 25187002.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    51. Measure of synchrony in the activity of intrinsic cardiac neurons. Physiol Meas. 2014 Apr; 35(4):549-66. Longpré JP, Salavatian S, Beaumont E, Armour JA, Ardell JL, Jacquemet V. PMID: 24621585.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Dynamic remodeling of the guinea pig intrinsic cardiac plexus induced by chronic myocardial infarction. Auton Neurosci. 2014 Apr; 181:4-12. Hardwick JC, Ryan SE, Beaumont E, Ardell JL, Southerland EM. PMID: 24220238.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    53. Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function. J Physiol. 2013 Sep 15; 591(18):4515-33. Beaumont E, Salavatian S, Southerland EM, Vinet A, Jacquemet V, Armour JA, Ardell JL. PMID: 23818689.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    54. Remodeling of intrinsic cardiac neurons: effects of ß-adrenergic receptor blockade in guinea pig models of chronic heart disease. . 2012 Nov 01; 303(9):R950-8. Hardwick JC, Southerland EM, Girasole AE, Ryan SE, Negrotto S, Ardell JL. PMID: 22933026.
      View in: PubMed   Mentions:
    55. Activated cranial cervical cord neurons affect left ventricular infarct size and the potential for sudden cardiac death. Auton Neurosci. 2012 Jul 02; 169(1):34-42. Southerland EM, Gibbons DD, Smith SB, Sipe A, Williams CA, Beaumont E, Armour JA, Foreman RD, Ardell JL. PMID: 22502863.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    56. Neuromodulation targets intrinsic cardiac neurons to attenuate neuronally mediated atrial arrhythmias. . 2012 Feb 01; 302(3):R357-64. Gibbons DD, Southerland EM, Hoover DB, Beaumont E, Armour JA, Ardell JL. PMID: 22088304.
      View in: PubMed   Mentions:
    57. Angiotensin II potentiates adrenergic and muscarinic modulation of guinea pig intracardiac neurons. . 2011 Nov; 301(5):R1391-9. Girasole AE, Palmer CP, Corrado SL, Marie Southerland E, Ardell JL, Hardwick JC. PMID: 21865545.
      View in: PubMed   Mentions:
    58. The cardiac neuronal hierarchy and susceptibility to arrhythmias. Heart Rhythm. 2011 Apr; 8(4):590-1. Ardell JL. PMID: 21167959.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    59. Sensory transduction of the ischemic myocardium. . 2010 Dec; 299(6):H1753-4. Ardell JL. PMID: 20952672.
      View in: PubMed   Mentions:
    60. Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload. . 2009 Sep; 297(3):R859-66. Hardwick JC, Baran CN, Southerland EM, Ardell JL. PMID: 19605763.
      View in: PubMed   Mentions:
    61. Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia. . 2009 Aug; 297(2):R470-7. Ardell JL, Cardinal R, Vermeulen M, Armour JA. PMID: 19515981.
      View in: PubMed   Mentions:
    62. Spatially divergent cardiac responses to nicotinic stimulation of ganglionated plexus neurons in the canine heart. Auton Neurosci. 2009 Jan 28; 145(1-2):55-62. Cardinal R, Pagé P, Vermeulen M, Ardell JL, Armour JA. PMID: 19071069.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    63. Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus. . 2008 Dec; 295(6):R1926-33. Hardwick JC, Southerland EM, Ardell JL. PMID: 18832084.
      View in: PubMed   Mentions:
    64. C2 spinal cord stimulation induces dynorphin release from rat T4 spinal cord: potential modulation of myocardial ischemia-sensitive neurons. . 2008 Nov; 295(5):R1519-28. Ding X, Hua F, Sutherly K, Ardell JL, Williams CA. PMID: 18753268.
      View in: PubMed   Mentions:
    65. Alpha-adrenoceptor blockade modifies neurally induced atrial arrhythmias. . 2008 Oct; 295(4):R1175-80. Richer LP, Vinet A, Kus T, Cardinal R, Ardell JL, Armour JA. PMID: 18716036.
      View in: PubMed   Mentions:
    66. Neurochemical diversity of afferent neurons that transduce sensory signals from dog ventricular myocardium. Auton Neurosci. 2008 Aug 18; 141(1-2):38-45. Hoover DB, Shepherd AV, Southerland EM, Armour JA, Ardell JL. PMID: 18558516.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    67. Modulation of cardiac ischemia-sensitive afferent neuron signaling by preemptive C2 spinal cord stimulation: effect on substance P release from rat spinal cord. . 2008 Jan; 294(1):R93-101. Ding X, Ardell JL, Hua F, McAuley RJ, Sutherly K, Daniel JJ, Williams CA. PMID: 17989135.
      View in: PubMed   Mentions:
    68. Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability. J Physiol. 2007 Jul 01; 582(Pt 1):87-93. Tompkins JD, Ardell JL, Hoover DB, Parsons RL. PMID: 17495034.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    69. Preemptive, but not reactive, spinal cord stimulation mitigates transient ischemia-induced myocardial infarction via cardiac adrenergic neurons. . 2007 Jan; 292(1):H311-7. Southerland EM, Milhorn DM, Foreman RD, Linderoth B, DeJongste MJ, Armour JA, Subramanian V, Singh M, Singh K, Ardell JL. PMID: 16920800.
      View in: PubMed   Mentions:
    70. Beta1-adrenoceptor blockade mitigates excessive norepinephrine release into cardiac interstitium in mitral regurgitation in dog. . 2006 Jul; 291(1):H147-51. Hankes GH, Ardell JL, Tallaj J, Wei CC, Aban I, Holland M, Rynders P, Dillon R, Cardinal R, Hoover DB, Armour JA, Husain A, Dell'Italia LJ. PMID: 16772522.
      View in: PubMed   Mentions:
    71. Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs. . 2006 Nov; 291(5):R1369-75. Cardinal R, Pagé P, Vermeulen M, Bouchard C, Ardell JL, Foreman RD, Armour JA. PMID: 16778070.
      View in: PubMed   Mentions:
    72. Stochastic behavior of atrial and ventricular intrinsic cardiac neurons. J Appl Physiol (1985). 2006 Aug; 101(2):413-9. Waldmann M, Thompson GW, Kember GC, Ardell JL, Armour JA. PMID: 16645188.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    73. Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure. Circ Res. 2005 Feb 04; 96(2):234-43. Katori T, Hoover DB, Ardell JL, Helm RH, Belardi DF, Tocchetti CG, Forfia PR, Kass DA, Paolocci N. PMID: 15591228.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    74. Left vagal stimulation induces dynorphin release and suppresses substance P release from the rat thoracic spinal cord during cardiac ischemia. . 2004 Dec; 287(6):R1468-77. Hua F, Ardell JL, Williams CA. PMID: 15297264.
      View in: PubMed   Mentions:
    75. Short-acting beta-adrenergic antagonist esmolol given at reperfusion improves survival after prolonged ventricular fibrillation. Circulation. 2004 May 25; 109(20):2469-74. Killingsworth CR, Wei CC, Dell'Italia LJ, Ardell JL, Kingsley MA, Smith WM, Ideker RE, Walcott GP. PMID: 15123529.
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    76. Spinal cord activation differentially modulates ischaemic electrical responses to different stressors in canine ventricles. Auton Neurosci. 2004 Mar 31; 111(1):37-47. Cardinal R, Ardell JL, Linderoth B, Vermeulen M, Foreman RD, Armour JA. PMID: 15109937.
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    77. Parasympathetic control of the heart. II. A novel interganglionic intrinsic cardiac circuit mediates neural control of heart rate. J Appl Physiol (1985). 2004 Jun; 96(6):2273-8. Gray AL, Johnson TA, Ardell JL, Massari VJ. PMID: 14978001.
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    78. Parasympathetic control of the heart. III. Neuropeptide Y-immunoreactive nerve terminals synapse on three populations of negative chronotropic vagal preganglionic neurons. J Appl Physiol (1985). 2004 Jun; 96(6):2279-87. Gray AL, Johnson TA, Lauenstein JM, Newton SS, Ardell JL, Massari VJ. PMID: 14978003.
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    79. Myocardial ischemia induces the release of substance P from cardiac afferent neurons in rat thoracic spinal cord. . 2004 May; 286(5):H1654-64. Hua F, Ricketts BA, Reifsteck A, Ardell JL, Williams CA. PMID: 14684370.
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    80. Intrinsic cardiac nervous system in tachycardia induced heart failure. . 2003 Nov; 285(5):R1212-23. Arora RC, Cardinal R, Smith FM, Ardell JL, Dell'Italia LJ, Armour JA. PMID: 12893651.
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    81. Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation. Circulation. 2003 Jul 15; 108(2):225-30. Tallaj J, Wei CC, Hankes GH, Holland M, Rynders P, Dillon AR, Ardell JL, Armour JA, Lucchesi PA, Dell'Italia LJ. PMID: 12847066.
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    82. Interactions within the intrinsic cardiac nervous system contribute to chronotropic regulation. . 2003 Nov; 285(5):R1066-75. Randall DC, Brown DR, McGuirt AS, Thompson GW, Armour JA, Ardell JL. PMID: 12842863.
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    83. Long-term modulation of the intrinsic cardiac nervous system by spinal cord neurons in normal and ischaemic hearts. Auton Neurosci. 2002 Jan 10; 95(1-2):71-9. Armour JA, Linderoth B, Arora RC, DeJongste MJ, Ardell JL, Kingma JG, Hill M, Foreman RD. PMID: 11873770.
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    84. Effects of chronic cardiac decentralization on functional properties of canine intracardiac neurons in vitro. . 2001 Nov; 281(5):R1474-82. Smith FM, McGuirt AS, Leger J, Armour JA, Ardell JL. PMID: 11641118.
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    85. Chronic decentralization of the heart differentially remodels canine intrinsic cardiac neuron muscarinic receptors. . 2001 Nov; 281(5):H1919-30. Smith FM, McGuirt AS, Hoover DB, Armour JA, Ardell JL. PMID: 11668052.
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    86. Neuromodulation therapy does not influence blood flow distribution or left-ventricular dynamics during acute myocardial ischemia. Auton Neurosci. 2001 Aug 13; 91(1-2):47-54. Kingma JG, Linderoth B, Ardell JL, Armour JA, DeJongste MJ, Foreman RD. PMID: 11515801.
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    87. Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo. . 2001 Aug; 281(2):H813-22. Farrell DM, Wei CC, Tallaj J, Ardell JL, Armour JA, Hageman GR, Bradley WE, Dell'Italia LJ. PMID: 11454586.
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    88. Functional interdependence of neurons in a single canine intrinsic cardiac ganglionated plexus. J Physiol. 2000 Nov 01; 528(Pt 3):561-71. Thompson GW, Collier K, Ardell JL, Kember G, Armour JA. PMID: 11060132.
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    89. Modulation of microvascular permeability by 21-aminosteroids after burn injuries. J Burn Care Rehabil. 2000 Sep-Oct; 21(5):406-13. Dyess DL, Collins JN, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. PMID: 11020047.
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    90. Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. Cardiovasc Res. 2000 Aug; 47(2):367-75. Foreman RD, Linderoth B, Ardell JL, Barron KW, Chandler MJ, Hull SS, TerHorst GJ, DeJongste MJ, Armour JA. PMID: 10946073.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    91. The heart reinnervates after transplantation. Ann Thorac Surg. 2000 Jun; 69(6):1769-81. Murphy DA, Thompson GW, Ardell JL, McCraty R, Stevenson RS, Sangalang VE, Cardinal R, Wilkinson M, Craig S, Smith FM, Kingma JG, Armour JA. PMID: 10892922.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    92. Regional blood flow response to hypothermia in premature, newborn, and neonatal piglets. J Pediatr Surg. 1999 Jan; 34(1):193-8. Powell RW, Dyess DL, Collins JN, Roberts WS, Tacchi EJ, Swafford AN, Ferrara JJ, Ardell JL. PMID: 10022170.
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    93. Organ blood flow redistribution in response to hypoxemia in neonatal piglets. J Invest Surg. 1998 Nov-Dec; 11(6):381-92. Dyess DL, Christenberry DP, Peeples GL, Collins JN, Ardell JL, Roberts WS, Tacchi EJ, Powell RW. PMID: 9895112.
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    94. Canine intrinsic cardiac neurons involved in cardiac regulation possess NK1, NK2, and NK3 receptors. Am J Physiol. 1998 11; 275(5):R1683-9. Thompson GW, Hoover DB, Ardell JL, Armour JA. PMID: 9791091.
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    95. Ablation of posterior atrial ganglionated plexus potentiates sympathetic tachycardia to behavioral stress. Am J Physiol. 1998 09; 275(3):R779-87. Randall DC, Brown DR, Li SG, Olmstead ME, Kilgore JM, Sprinkle AG, Randall WC, Ardell JL. PMID: 9728075.
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    96. Differential selectivity of cardiac neurons in separate intrathoracic autonomic ganglia. Am J Physiol. 1998 04; 274(4):R939-49. Armour JA, Collier K, Kember G, Ardell JL. PMID: 9575954.
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    97. Vascular tree structure affects lung blood flow heterogeneity simulated in three dimensions. J Appl Physiol (1985). 1997 Oct; 83(4):1370-82. Parker JC, Cave CB, Ardell JL, Hamm CR, Williams SG. PMID: 9338448.
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    98. Autonomic interactions for control of atrial rate are maintained after SA nodal parasympathectomy. Am J Physiol. 1997 Jun; 272(6 Pt 2):H2525-33. McGuirt AS, Schmacht DC, Ardell JL. PMID: 9227527.
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    99. Cardiac augmentation can be maintained by continuous exposure of intrinsic cardiac neurons to a beta-adrenergic agonist or angiotensin II. J Surg Res. 1996 Dec; 66(2):167-73. Levett JM, Murphy DA, McGuirt AS, Ardell JL, Armour JA. PMID: 9024830.
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    100. Endogenous myocardial norepinephrine is not essential for ischemic preconditioning in rabbit heart. Am J Physiol. 1996 Mar; 270(3 Pt 2):H1078-84. Ardell JL, Yang XM, Barron BA, Downey JM, Cohen MV. PMID: 8780206.
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    101. Role of bradykinin in protection of ischemic preconditioning in rabbit hearts. Circ Res. 1995 Sep; 77(3):611-21. Goto M, Liu Y, Yang XM, Ardell JL, Cohen MV, Downey JM. PMID: 7641331.
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    102. Regional blood flow redistribution in preterm piglets with hemorrhage and resuscitation. J Surg Res. 1995 Jul; 59(1):29-34. Dyess DL, Powell RW, Roberts WS, Tacchi EJ, Swafford AN, Ferrara JJ, Ardell JL. PMID: 7630133.
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    103. Effects of dopamine and dobutamine on regional blood flow distribution in the neonatal piglet. Ann Surg. 1995 May; 221(5):531-40; discussion 540-2. Ferrara JJ, Dyess DL, Peeples GL, Christenberry DP, Roberts WS, Tacchi EJ, Swafford AN, Ardell JL, Powell RW. PMID: 7748035.
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    104. Regional pulmonary blood flow during rest, tilt, and exercise in unanesthetized dogs. J Appl Physiol (1985). 1995 Mar; 78(3):838-46. Parker JC, Ardell JL, Hamm CR, Barman SA, Coker PJ. PMID: 7775327.
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    105. Effect of phorbol myristate acetate-induced lung injury on airway blood flow. Respir Physiol. 1995 Feb; 99(2):249-57. Barman SA, Ardell JL, Taylor AE. PMID: 7777708.
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    106. Effects of graded thermal injury on microvascular permeability at the site of injury. J Surg Res. 1994 Sep; 57(3):420-6. Ferrara JJ, Dyess DL, Collins JN, Fish JM, Markert AJ, Ardell JL, Townsley MI, Flint LM, Taylor AE. PMID: 8072291.
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    107. Redistribution of organ blood flow after hemorrhage and resuscitation in full-term piglets. J Pediatr Surg. 1994 Aug; 29(8):1097-102. Dyess DL, Powell RW, Swafford AN, Schmacht DC, Roberts WS, Ferrara JJ, Ardell JL. PMID: 7525918.
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    108. Altered pulmonary microvascular reactivity to norepinephrine in canine pacing-induced heart failure. Circ Res. 1994 Aug; 75(2):347-56. Townsley MI, Pitts VH, Ardell JL, Zhao Z, Johnson WH. PMID: 7518365.
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    109. Development of a protocol to provide prolonged general anesthesia to pregnant sows. J Invest Surg. 1994 May-Jun; 7(3):235-42. Dyess DL, Tacchi E, Powell RQ, Ardell JL, Roberts WS, Ferrara JJ. PMID: 7918245.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    110. Gross and microscopic anatomy of the canine intrinsic cardiac nervous system. Anat Rec. 1994 May; 239(1):75-87. Yuan BX, Ardell JL, Hopkins DA, Losier AM, Armour JA. PMID: 8037379.
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    111. Effects of pentafraction administration on microvascular permeability alterations induced by graded thermal injury. Surgery. 1994 Feb; 115(2):182-9. Ferrara JJ, Dyess DL, Collins JN, Fish JM, Ardell JL, Townsley MI, Taylor AE, Flint LM. PMID: 7508639.
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    112. Effects of antioxidants on the blood-brain barrier and postischemic hyperemia. Acta Neurochir (Wien). 1994; 131(3-4):302-9. Tasdemiroglu E, Christenberry PD, Ardell JL, Chronister RB, Taylor AE. PMID: 7754839.
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    113. The effects of albumin administration on microvascular permeability at the site of burn injury. J Trauma. 1994 Jan; 36(1):27-33. Collins JN, Dyess DL, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. PMID: 8295246.
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    114. Effects of left atrial and airway pressures on airway blood flow. Respir Physiol. 1993 Oct; 94(1):61-74. Barman SA, Ardell JL, Taylor AE. PMID: 8272582.
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    115. Indomethacin-induced blood flow distribution in premature and full-term piglets. J Pediatr Surg. 1993 Oct; 28(10):1396-400. Dyess DL, Peeples GL, Ardell JL, Tacchi EJ, Roberts WS, Ferrara JJ, Powell RW. PMID: 8263708.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    116. Differential cardiac responses induced by nicotine sensitive canine atrial and ventricular neurones. Cardiovasc Res. 1993 May; 27(5):760-9. Yuan BX, Ardell JL, Hopkins DA, Armour JA. PMID: 8348576.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    117. Effect of superoxide dismutase on acute reperfusion injury of the rabbit brain. Acta Neurochir (Wien). 1993; 120(3-4):180-6. Tasdemiroglu E, Chistenberry PD, Ardell JL, Chronister RB, Taylor AE. PMID: 8460572.
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    118. Effects of transient coronary artery occlusion on canine intrinsic cardiac neuronal activity. Integr Physiol Behav Sci. 1993 Jan-Mar; 28(1):5-21. Huang MH, Ardell JL, Hanna BD, Wolf SG, Armour JA. PMID: 8476742.
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    119. Effect of endothelin-1 on canine airway blood flow. J Cardiovasc Pharmacol. 1993; 22 Suppl 8:S274-7. Barman SA, Ardell JL, Taylor AE. PMID: 7509964.
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    120. Effects of hypertonic saline and dextran 70 resuscitation on microvascular permeability after burn. Am J Physiol. 1992 Jun; 262(6 Pt 2):H1832-7. Dyess DL, Ardell JL, Townsley MI, Taylor AE, Ferrara JJ. PMID: 1377878.
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    121. Activity of in vivo atrial and ventricular neurons in chronically decentralized canine hearts. Am J Physiol. 1991 Mar; 260(3 Pt 2):H713-21. Ardell JL, Butler CK, Smith FM, Hopkins DA, Armour JA. PMID: 2000967.
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    122. Autonomic regulation of subsidiary atrial pacemakers during exercise. J Appl Physiol (1985). 1991 Mar; 70(3):1175-83. Ardell JL, Randall WC, Pomeroy G, Lawton M, Kim T. PMID: 2032983.
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    123. Regional blood flow to canine parietal pleura and internal intercostal muscle. J Appl Physiol (1985). 1991 Jan; 70(1):97-102. Townsley MI, Negrini D, Ardell JL. PMID: 2010416.
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    124. Nerve-sparing dissection as alternative to anesthesia of carotid sinus nerve in preparation for carotid endarterectomy. Tex Heart Inst J. 1989; 16(2):107-9. Barman AA, Moideen AS, Chaudhry SS, Ardell J, Barman SA, Cantu R. PMID: 15227222.
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    125. Differential sympathetic regulation of automatic, conductile, and contractile tissue in dog heart. Am J Physiol. 1988 Nov; 255(5 Pt 2):H1050-9. Ardell JL, Randall WC, Cannon WJ, Schmacht DC, Tasdemiroglu E. PMID: 3189569.
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    126. Pulmonary and systemic blood flow contributions to upper airways in canine lung. Am J Physiol. 1988 Nov; 255(5 Pt 2):H1130-5. Barman SA, Ardell JL, Parker JC, Perry ML, Taylor AE. PMID: 3189574.
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    127. Differential autonomic control of SAN and AVN regions of the canine heart: structure and function. Prog Clin Biol Res. 1988; 275:15-31. Randall WC, Ardell JL, O'Toole MF, Wurster RD. PMID: 3051007.
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    128. Selective ganglionic blockade of vagal inputs to sinoatrial and/or atrioventricular regions. J Pharmacol Exp Ther. 1987 Sep; 242(3):1006-12. Fee JD, Randall WC, Wurster RD, Ardell JL. PMID: 2888868.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    129. Vagal postganglionic innervation of the canine sinoatrial node. J Auton Nerv Syst. 1987 Jul; 20(1):13-23. Randall WC, Ardell JL, Wurster RD, Milosavljevic M. PMID: 3655182.
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    130. Selective vagal innervation of sinoatrial and atrioventricular nodes in canine heart. Am J Physiol. 1986 Oct; 251(4 Pt 2):H764-73. Ardell JL, Randall WC. PMID: 3021001.
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    131. Spinal opiate modulation of cardiovascular reflexes in the exercising dog. Brain Res. 1986 Sep 03; 381(2):385-9. Pomeroy G, Ardell JL, Wurster RD. PMID: 3019479.
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    132. Functional interdependence of discrete vagal projections to SA and AV nodes. Am J Physiol. 1986 Aug; 251(2 Pt 2):H398-404. O'Toole MF, Ardell JL, Randall WC. PMID: 3017130.
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    133. Parasympathetic ganglia innervating the canine atrioventricular nodal region. J Auton Nerv Syst. 1986 Aug; 16(4):311-23. Randall WC, Ardell JL, Calderwood D, Milosavljevic M, Goyal SC. PMID: 3745782.
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    134. Selective vagal innervation of the heart. Ann Clin Lab Sci. 1986 May-Jun; 16(3):198-208. Randall WC, Milosavljevic M, Wurster RD, Geis GS, Ardell JL. PMID: 2872849.
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    135. Cardiac responses to exercise in the dog before and after destruction of the sinoatrial node. Eur J Appl Physiol Occup Physiol. 1986; 55(3):253-8. Kim KS, Ardell JL, Randall WC, Pomeroy G, Calderwood D. PMID: 2874023.
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    136. Differential responses accompanying sequential stimulation and ablation of vagal branches to dog heart. Am J Physiol. 1985 Jul; 249(1 Pt 2):H133-40. Randall WC, Ardell JL, Becker DM. PMID: 4014479.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    137. Selective parasympathectomy of automatic and conductile tissues of the canine heart. Am J Physiol. 1985 Jan; 248(1 Pt 2):H61-8. Randall WC, Ardell JL. PMID: 3970176.
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    138. Cardiovascular responses to graded reductions in hindlimb perfusion in exercising dogs. Am J Physiol. 1983 Sep; 245(3):H481-6. Wyss CR, Ardell JL, Scher AM, Rowell LB. PMID: 6614196.
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    139. Sympathetic nerve discharge in chronic spinal cat. Am J Physiol. 1982 Sep; 243(3):H463-70. Ardell JL, Barman SM, Gebber GL. PMID: 7114277.
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