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Prioritizing Genetic Contributors to Cortical Alterations in 22q11.2 Deletion Syndrome Using Imaging Transcriptomics. Cereb Cortex. 2021 Jun 10; 31(7):3285-3298.
Forsyth JK, Mennigen E, Lin A, Sun D, Vajdi A, Kushan-Wells L, Ching CRK, Villalon-Reina JE, Thompson PM, 22q11.2 ENIGMA Consortium , Bearden CE. PMID: 33638978.
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Cross-paradigm connectivity: reliability, stability, and utility. Brain Imaging Behav. 2021 Apr; 15(2):614-629.
Cao H, Chen OY, McEwen SC, Forsyth JK, Gee DG, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Carrión RE, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Thermenos H, Tsuang MT, van Erp TGM, Walker EF, Hamann S, Anticevic A, Woods SW, Cannon TD. PMID: 32361945.
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Humans
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Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness. Am J Psychiatry. 2020 07 01; 177(7):589-600.
Ching CRK, Gutman BA, Sun D, Villalon Reina J, Ragothaman A, Isaev D, Zavaliangos-Petropulu A, Lin A, Jonas RK, Kushan L, Pacheco-Hansen L, Vajdi A, Forsyth JK, Jalbrzikowski M, Bakker G, van Amelsvoort T, Antshel KM, Fremont W, Kates WR, Campbell LE, McCabe KL, Craig MC, Daly E, Gudbrandsen M, Murphy CM, Murphy DG, Murphy KC, Fiksinski A, Koops S, Vorstman J, Crowley TB, Emanuel BS, Gur RE, McDonald-McGinn DM, Roalf DR, Ruparel K, Schmitt JE, Zackai EH, Durdle CA, Goodrich-Hunsaker NJ, Simon TJ, Bassett AS, Butcher NJ, Chow EWC, Vila-Rodriguez F, Cunningham A, Doherty J, Linden DE, Moss H, Owen MJ, van den Bree M, Crossley NA, Repetto GM, Thompson PM, Bearden CE. PMID: 32046535.
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8 Fields:
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Humans
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Genetics of Childhood-onset Schizophrenia 2019 Update. Child Adolesc Psychiatr Clin N Am. 2020 01; 29(1):157-170.
Forsyth JK, Asarnow RF. PMID: 31708045.
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3 Fields:
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Humans
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Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study. Mol Psychiatry. 2020 11; 25(11):2818-2831.
Villalón-Reina JE, Martínez K, Qu X, Ching CRK, Nir TM, Kothapalli D, Corbin C, Sun D, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL, Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Emanuel B, McDonald-McGinn DM, Vorstman JAS, Fiksinski AM, Koops S, Ruparel K, Roalf D, Gur RE, Eric Schmitt J, Simon TJ, Goodrich-Hunsaker NJ, Durdle CA, Doherty JL, Cunningham AC, van den Bree M, Linden DEJ, Owen M, Moss H, Kelly S, Donohoe G, Murphy KC, Arango C, Jahanshad N, Thompson PM, Bearden CE. PMID: 31358905.
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PubMed Mentions:
8 Fields:
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Humans
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Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders. Biol Psychiatry. 2020 01 15; 87(2):150-163.
Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, Bearden CE. PMID: 31500805.
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9 Fields:
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Humans
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Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior. J Neurosci. 2019 05 01; 39(18):3561-3581.
Gokhale A, Hartwig C, Freeman AAH, Bassell JL, Zlatic SA, Sapp Savas C, Vadlamudi T, Abudulai F, Pham TT, Crocker A, Werner E, Wen Z, Repetto GM, Gogos JA, Claypool SM, Forsyth JK, Bearden CE, Glausier J, Lewis DA, Seyfried NT, Kwong JQ, Faundez V. PMID: 30833507.
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11 Fields:
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HumansAnimalsCells
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Toward Leveraging Human Connectomic Data in Large Consortia: Generalizability of fMRI-Based Brain Graphs Across Sites, Sessions, and Paradigms. Cereb Cortex. 2019 03 01; 29(3):1263-1279.
Cao H, McEwen SC, Forsyth JK, Gee DG, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Carrión RE, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Seidman LJ, Thermenos H, Tsuang MT, van Erp TGM, Walker EF, Hamann S, Anticevic A, Woods SW, Cannon TD. PMID: 29522112.
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PubMed Mentions:
10 Fields:
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Humans
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The many roads to psychosis: recent advances in understanding risk and mechanisms. F1000Res. 2018; 7.
Bearden CE, Forsyth JK. PMID: 30631427.
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3 Fields:
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Humans
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Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization. Nat Commun. 2018 09 21; 9(1):3836.
Cao H, Chén OY, Chung Y, Forsyth JK, McEwen SC, Gee DG, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Carrión RE, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Seidman LJ, Thermenos H, Tsuang MT, van Erp TGM, Walker EF, Hamann S, Anticevic A, Woods SW, Cannon TD. PMID: 30242220.
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35 Fields:
Translation:
Humans
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Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size. Mol Psychiatry. 2020 08; 25(8):1822-1834.
Sun D, Ching CRK, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Villalon-Reina JE, Qu X, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL, Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Vorstman J, Fiksinski A, Koops S, Ruparel K, Roalf DR, Gur RE, Schmitt JE, Simon TJ, Goodrich-Hunsaker NJ, Durdle CA, Bassett AS, Chow EWC, Butcher NJ, Vila-Rodriguez F, Doherty J, Cunningham A, van den Bree MBM, Linden DEJ, Moss H, Owen MJ, Murphy KC, McDonald-McGinn DM, Emanuel B, van Erp TGM, Turner JA, Thompson PM, Bearden CE. PMID: 29895892.
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30 Fields:
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Humans
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Reliability of functional magnetic resonance imaging activation during working memory in a multisite study: Clarification and implications for statistical power. Neuroimage. 2017 12; 163:456-458.
Cannon TD, Cao H, Mathalon DH, Forsyth J, NAPLS consortium . PMID: 29113944.
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2 Fields:
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Humans
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Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine. Schizophr Bull. 2017 09 01; 43(5):1123-1133.
Forsyth JK, Bachman P, Mathalon DH, Roach BJ, Ye E, Asarnow RF. PMID: 28338977.
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7 Fields:
Translation:
HumansCells
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Mapping the Consequences of Impaired Synaptic Plasticity in Schizophrenia through Development: An Integrative Model for Diverse Clinical Features. Trends Cogn Sci. 2017 Oct; 21(10):760-778.
Forsyth JK, Lewis DA. PMID: 28754595.
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25 Fields:
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HumansCells
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Intrinsic Connectivity Network-Based Classification and Detection of Psychotic Symptoms in Youth With 22q11.2 Deletions. Cereb Cortex. 2017 06 01; 27(6):3294-3306.
Schreiner M, Forsyth JK, Karlsgodt KH, Anderson AE, Hirsh N, Kushan L, Uddin LQ, Mattiacio L, Coman IL, Kates WR, Bearden CE. PMID: 28383675.
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6 Fields:
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Humans
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Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15331-6.
Forsyth JK, Bachman P, Mathalon DH, Roach BJ, Asarnow RF. PMID: 26621715.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Reliability of an fMRI paradigm for emotional processing in a multisite longitudinal study. Hum Brain Mapp. 2015 Jul; 36(7):2558-79.
Gee DG, McEwen SC, Forsyth JK, Haut KM, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Olvet D, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Seidman LJ, Thermenos H, Tsuang MT, van Erp TG, Walker EF, Hamann S, Woods SW, Constable T, Cannon TD. PMID: 25821147.
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PubMed Mentions:
25 Fields:
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Humans
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Reliability of functional magnetic resonance imaging activation during working memory in a multi-site study: analysis from the North American Prodrome Longitudinal Study. Neuroimage. 2014 Aug 15; 97:41-52.
Forsyth JK, McEwen SC, Gee DG, Bearden CE, Addington J, Goodyear B, Cadenhead KS, Mirzakhanian H, Cornblatt BA, Olvet DM, Mathalon DH, McGlashan TH, Perkins DO, Belger A, Seidman LJ, Thermenos HW, Tsuang MT, van Erp TG, Walker EF, Hamann S, Woods SW, Qiu M, Cannon TD. PMID: 24736173.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Impaired cerebellar-dependent eyeblink conditioning in first-degree relatives of individuals with schizophrenia. Schizophr Bull. 2014 Sep; 40(5):1001-10.
Bolbecker AR, Kent JS, Petersen IT, Klaunig MJ, Forsyth JK, Howell JM, Westfall DR, O'Donnell BF, Hetrick WP. PMID: 23962891.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Genetics of childhood-onset schizophrenia. Child Adolesc Psychiatr Clin N Am. 2013 Oct; 22(4):675-87.
Asarnow RF, Forsyth JK. PMID: 24012080.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Genetic risk for schizophrenia, obstetric complications, and adolescent school outcome: evidence for gene-environment interaction. Schizophr Bull. 2013 Sep; 39(5):1067-76.
Forsyth JK, Ellman LM, Tanskanen A, Mustonen U, Huttunen MO, Suvisaari J, Cannon TD. PMID: 22941745.
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14 Fields:
Translation:
Humans
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Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. PLoS One. 2012; 7(8):e41808.
Kent JS, Hong SL, Bolbecker AR, Klaunig MJ, Forsyth JK, O'Donnell BF, Hetrick WP. PMID: 22870250.
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PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
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Computer-assisted cognitive remediation for schizophrenia: a randomized single-blind pilot study. Schizophr Res. 2012 Aug; 139(1-3):92-8.
Rass O, Forsyth JK, Bolbecker AR, Hetrick WP, Breier A, Lysaker PH, O'Donnell BF. PMID: 22682988.
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17 Fields:
Translation:
Humans
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Auditory steady state response in the schizophrenia, first-degree relatives, and schizotypal personality disorder. Schizophr Res. 2012 Apr; 136(1-3):143-9.
Rass O, Forsyth JK, Krishnan GP, Hetrick WP, Klaunig MJ, Breier A, O'Donnell BF, Brenner CA. PMID: 22285558.
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28 Fields:
Translation:
Humans
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Exploration of cerebellar-dependent associative learning in schizophrenia: effects of varying and shifting interstimulus interval on eyeblink conditioning. Behav Neurosci. 2011 Oct; 125(5):687-98.
Bolbecker AR, Steinmetz AB, Mehta CS, Forsyth JK, Klaunig MJ, Lazar EK, Steinmetz JE, O'Donnell BF, Hetrick WP. PMID: 21942432.
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12 Fields:
Translation:
Humans
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Temporal discounting of rewards in patients with bipolar disorder and schizophrenia. J Abnorm Psychol. 2011 Nov; 120(4):911-21.
Ahn WY, Rass O, Fridberg DJ, Bishara AJ, Forsyth JK, Breier A, Busemeyer JR, Hetrick WP, Bolbecker AR, O'Donnell BF. PMID: 21875166.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Paced finger-tapping abnormalities in bipolar disorder indicate timing dysfunction. Bipolar Disord. 2011 Feb; 13(1):99-110.
Bolbecker AR, Hong SL, Kent JS, Forsyth JK, Klaunig MJ, Lazar EK, O'Donnell BF, Hetrick WP. PMID: 21320257.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Cerebellar-dependent eyeblink conditioning deficits in schizophrenia spectrum disorders. Schizophr Bull. 2012 Jun; 38(4):751-9.
Forsyth JK, Bolbecker AR, Mehta CS, Klaunig MJ, Steinmetz JE, O'Donnell BF, Hetrick WP. PMID: 21148238.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Neonatal ventral hippocampal lesions in male and female rats: effects on water maze, locomotor activity, plus-maze and prefrontal cortical GABA and glutamate release in adulthood. Behav Brain Res. 2009 Sep 14; 202(2):198-209.
Beninger RJ, Tuerke KJ, Forsyth JK, Giles A, Xue L, Boegman RJ, Jhamandas K. PMID: 19463702.
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9 Fields:
Translation:
Animals
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Subchronic MK-801 behavioural deficits in rats: partial reversal by the novel nitrate GT 1061. Pharmacol Biochem Behav. 2009 Feb; 91(4):495-502.
Beninger RJ, Forsyth JK, Van Adel M, Reynolds JN, Boegman RJ, Jhamandas K. PMID: 18834899.
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PubMed Mentions:
8 Fields:
Translation:
Animals