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Jerome Engel

Title(s)Professor, Neurology
SchoolMedicine
Phone3108255745
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    Other Positions
    Title(s)Professor, Neurobiology

    Title(s)Professor, Psychiatry and Biobehavioral Sciences


    Collapse Research 
    Collapse Research Activities and Funding
    The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)
    NIH/NINDS U54NS100064Jan 15, 2017 - Nov 30, 2021
    Role: Co-Principal Investigator
    The Epilepsy Bioinformatics Study (EpiBioS)
    NIH/NINDS P20NS080181Sep 1, 2012 - Aug 31, 2015
    Role: Principal Investigator
    Early Randomized Surgical Epilepsy Trial
    NIH/NINDS U01NS042372Sep 1, 2002 - Nov 30, 2008
    Role: Principal Investigator
    MULTICENTER RANDOMIZED CLINICAL TRIAL
    NIH/NINDS R21NS037897Jul 15, 1999 - Dec 31, 2001
    Role: Principal Investigator
    IN VIVO STUDIES OF THE EPILEPTIC HIPPOCAMPUS
    NIH/NINDS R37NS033310Aug 1, 1994 - Nov 30, 2010
    Role: Principal Investigator
    In Vivo Studies of the Epileptic Hippocampus
    NIH/NINDS R01NS033310Aug 1, 1994 - Nov 30, 2003
    Role: Principal Investigator
    INTERNAT CONFERENCE ON SURGICAL TREATMENT OF EPILEPSY
    NIH/NINDS R13NS029615Feb 1, 1992 - Jan 31, 1993
    Role: Principal Investigator
    INTERNATIONAL &COOPERATIVE PROJECTS STUDY SECTION
    NIH/CSR U09RG000129Jul 1, 1989 - Jun 30, 1992
    Role: Co-Principal Investigator
    BIOMEDICAL SCIENCES (SUBCOMMITTEE 4)
    NIH/CSR U09RG000016Jul 1, 1988 - Jun 30, 1991
    Role: Co-Principal Investigator
    Clinical Research Program for the Partial Epilepsies
    NIH/NINDS P01NS002808Jan 1, 1985 - Sep 29, 2000
    Role: Principal Investigator
    INTERNATIONAL CONFERENCE ON SURGICAL THERAPY OF EPILEPSY
    NIH/NINDS R13NS021444Dec 1, 1984 - Nov 30, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Weiss SA, Song I, Leng M, Pastore T, Slezak D, Waldman Z, Orosz I, Gorniak R, Donmez M, Sharan A, Wu C, Fried I, Sperling MR, Bragin A, Engel J, Nir Y, Staba R. Ripples Have Distinct Spectral Properties and Phase-Amplitude Coupling With Slow Waves, but Indistinct Unit Firing, in Human Epileptogenic Hippocampus. Front Neurol. 2020; 11:174. PMID: 32292384.
      View in: PubMed
    2. Tatekawa H, Kerr WT, Savic I, Engel J, Salamon N. Reduced left amygdala volume in patients with dissociative seizures (psychogenic nonepileptic seizures). Seizure. 2020 Feb; 75:43-48. PMID: 31874358.
      View in: PubMed
    3. Ferando I, Soss JR, Elder C, Shah V, Lo Russo G, Tassi L, Tassinari CA, Engel J. Hand posture as localizing sign in adult focal epileptic seizures. Ann Neurol. 2019 Nov; 86(5):793-800. PMID: 31498917.
      View in: PubMed
    4. Engel J. Evolution of concepts in epilepsy surgery. Epileptic Disord. 2019 Oct 01; 21(5):391-409. PMID: 31708489.
      View in: PubMed
    5. Engel J, Pitkänen A. Biomarkers for epileptogenesis and its treatment. Neuropharmacology. 2019 Aug 01; 107735. PMID: 31377200.
      View in: PubMed
    6. Li L, Bragin A, Staba R, Engel J. Unit firing and oscillations at seizure onset in epileptic rodents. Neurobiol Dis. 2019 07; 127:382-389. PMID: 30928646.
      View in: PubMed
    7. Kerr WT, Chau AM, Janio EA, Braesch CT, Le JM, Hori JM, Patel AB, Gallardo NL, Bauirjan J, Allas CH, Karimi AH, Hwang ES, Davis EC, Buchard A, Torres-Barba D, D'Ambrosio S, Al Banna M, Cho AY, Engel J, Cohen MS, Stern JM. Reliability of reported peri-ictal behavior to identify psychogenic nonepileptic seizures. Seizure. 2019 Apr; 67:45-51. PMID: 30884437.
      View in: PubMed
    8. Weiss SA, Staba R, Bragin A, Moxon K, Sperling M, Avoli M, Engel J. "Interneurons and principal cell firing in human limbic areas at focal seizure onset". Neurobiol Dis. 2019 04; 124:183-188. PMID: 30471414.
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    9. Galanopoulou AS, Engel J, Moshé SL. PREFACE: Antiepileptogenesis following traumatic brain injury. Neurobiol Dis. 2019 03; 123:1-2. PMID: 30312758.
      View in: PubMed
    10. Elahian B, Lado NE, Mankin E, Vangala S, Misra A, Moxon K, Fried I, Sharan A, Yeasin M, Staba R, Bragin A, Avoli M, Sperling MR, Engel J, Weiss SA. Low-voltage fast seizures in humans begin with increased interneuron firing. Ann Neurol. 2018 10; 84(4):588-600. PMID: 30179277.
      View in: PubMed
    11. Engel J, Bragin A, Staba R. Nonictal EEG biomarkers for diagnosis and treatment. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):120-126. PMID: 30564770.
      View in: PubMed
    12. Vespa PM, Shrestha V, Abend N, Agoston D, Au A, Bell MJ, Bleck TP, Blanco MB, Claassen J, Diaz-Arrastia R, Duncan D, Ellingson B, Foreman B, Gilmore EJ, Hirsch L, Hunn M, Kamnaksh A, McArthur D, Morokoff A, O'Brien T, O'Phelan K, Robertson CL, Rosenthal E, Staba R, Toga A, Willyerd FA, Zimmermann L, Yam E, Martinez S, Real C, Engel J. The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol. Neurobiol Dis. 2019 03; 123:110-114. PMID: 30048805.
      View in: PubMed
    13. Weiss SA, Berry B, Chervoneva I, Waldman Z, Guba J, Bower M, Kucewicz M, Brinkmann B, Kremen V, Khadjevand F, Varatharajah Y, Guragain H, Sharan A, Wu C, Staba R, Engel J, Sperling M, Worrell G. Visually validated semi-automatic high-frequency oscillation detection aides the delineation of epileptogenic regions during intra-operative electrocorticography. Clin Neurophysiol. 2018 10; 129(10):2089-2098. PMID: 30077870.
      View in: PubMed
    14. Ogren JA, Tripathi R, Macey PM, Kumar R, Stern JM, Eliashiv DS, Allen LA, Diehl B, Engel J, Rani MRS, Lhatoo SD, Harper RM. Regional cortical thickness changes accompanying generalized tonic-clonic seizures. Neuroimage Clin. 2018; 20:205-215. PMID: 30094170.
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    15. Tubi MA, Lutkenhoff E, Blanco MB, McArthur D, Villablanca P, Ellingson B, Diaz-Arrastia R, Van Ness P, Real C, Shrestha V, Engel J, Vespa PM. Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study. Neurobiol Dis. 2019 03; 123:115-121. PMID: 29859872.
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    16. Vakharia VN, Duncan JS, Witt JA, Elger CE, Staba R, Engel J. Getting the best outcomes from epilepsy surgery. Ann Neurol. 2018 04; 83(4):676-690. PMID: 29534299.
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    17. Engel J. Epileptogenesis, traumatic brain injury, and biomarkers. Neurobiol Dis. 2019 03; 123:3-7. PMID: 29625256.
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    18. Engel J. The current place of epilepsy surgery. Curr Opin Neurol. 2018 04; 31(2):192-197. PMID: 29278548.
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    19. Li L, Patel M, Almajano J, Engel J, Bragin A. Extrahippocampal high-frequency oscillations during epileptogenesis. Epilepsia. 2018 04; 59(4):e51-e55. PMID: 29508901.
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    20. Kerr WT, Janio EA, Braesch CT, Le JM, Hori JM, Patel AB, Gallardo NL, Bauirjan J, Chau AM, Hwang ES, Davis EC, Buchard A, Torres-Barba D, D'Ambrosio S, Al Banna M, Cho AY, Engel J, Cohen MS, Stern JM. An objective score to identify psychogenic seizures based on age of onset and history. Epilepsy Behav. 2018 03; 80:75-83. PMID: 29414562.
      View in: PubMed
    21. Li L, Kriukova K, Engel J, Bragin A. Seizure development in the acute intrahippocampal epileptic focus. Sci Rep. 2018 01 23; 8(1):1423. PMID: 29362494.
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    22. Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W. Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia. 2018 01; 59(1):37-66. PMID: 29247482.
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    23. Shimamoto S, Waldman ZJ, Orosz I, Song I, Bragin A, Fried I, Engel J, Staba R, Sharan A, Wu C, Sperling MR, Weiss SA. Utilization of independent component analysis for accurate pathological ripple detection in intracranial EEG recordings recorded extra- and intra-operatively. Clin Neurophysiol. 2018 01; 129(1):296-307. PMID: 29113719.
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    24. Reed CM, Dewar S, Fried I, Engel J, Eliashiv D. Failed epilepsy surgery deserves a second chance. Clin Neurol Neurosurg. 2017 Dec; 163:110-115. PMID: 29096138.
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    25. Waldman ZJ, Shimamoto S, Song I, Orosz I, Bragin A, Fried I, Engel J, Staba R, Sperling MR, Weiss SA. A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings. Clin Neurophysiol. 2018 01; 129(1):308-318. PMID: 29122445.
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    26. Song I, Orosz I, Chervoneva I, Waldman ZJ, Fried I, Wu C, Sharan A, Salamon N, Gorniak R, Dewar S, Bragin A, Engel J, Sperling MR, Staba R, Weiss SA. Bimodal coupling of ripples and slower oscillations during sleep in patients with focal epilepsy. Epilepsia. 2017 11; 58(11):1972-1984. PMID: 28948998.
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    27. Kerr WT, Janio EA, Braesch CT, Le JM, Hori JM, Patel AB, Gallardo NL, Bauirjan J, D'Ambrosio SR, Chau AM, Hwang ES, Davis EC, Buchard A, Torres-Barba D, Al Banna M, Barritt SE, Cho AY, Engel J, Cohen MS, Stern JM. Identifying psychogenic seizures through comorbidities and medication history. Epilepsia. 2017 11; 58(11):1852-1860. PMID: 28895657.
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    28. Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J, Forsgren L, French JA, Hesdorffer DC, Lee BI, Mathern GW, Moshe SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S. How long for epilepsy remission in the ILAE definition? Epilepsia. 2017 08; 58(8):1486-1487. PMID: 28799662.
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    29. Frauscher B, Bartolomei F, Kobayashi K, Cimbalnik J, van 't Klooster MA, Rampp S, Otsubo H, Höller Y, Wu JY, Asano E, Engel J, Kahane P, Jacobs J, Gotman J. High-frequency oscillations: The state of clinical research. Epilepsia. 2017 08; 58(8):1316-1329. PMID: 28666056.
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    30. Jozwiak S, Becker A, Cepeda C, Engel J, Gnatkovsky V, Huberfeld G, Kaya M, Kobow K, Simonato M, Loeb JA. WONOEP appraisal: Development of epilepsy biomarkers-What we can learn from our patients? Epilepsia. 2017 06; 58(6):951-961. PMID: 28387933.
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    31. Kerr WT, Janio EA, Braesch CT, Le JM, Hori JM, Patel AB, Barritt SE, Gallardo NL, Bauirjan J, Chau AM, Hwang ES, Davis EC, Torres-Barba D, Cho AY, Engel J, Cohen MS, Stern JM. Diagnostic implications of review-of-systems questionnaires to differentiate epileptic seizures from psychogenic seizures. Epilepsy Behav. 2017 04; 69:69-74. PMID: 28236725.
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    32. Weiss SA, Asadi-Pooya AA, Vangala S, Moy S, Wyeth DH, Orosz I, Gibbs M, Schrader L, Lerner J, Cheng CK, Chang E, Rajaraman R, Keselman I, Churchman P, Bower-Baca C, Numis AL, Ho MG, Rao L, Bhat A, Suski J, Asadollahi M, Ambrose T, Fernandez A, Nei M, Skidmore C, Mintzer S, Eliashiv DS, Mathern GW, Nuwer MR, Sperling M, Engel J, Stern JM. AR2, a novel automatic muscle artifact reduction software method for ictal EEG interpretation: Validation and comparison of performance with commercially available software. F1000Res. 2017; 6:30. PMID: 28491280.
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    33. Engel J. What can we do for people with drug-resistant epilepsy? The 2016 Wartenberg Lecture. Neurology. 2016 Dec 06; 87(23):2483-2489. PMID: 27920283.
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    34. Engel J. Go with the flow. Epilepsy Behav. 2017 01; 66:135-137. PMID: 27842976.
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    35. Weiss SA, Orosz I, Salamon N, Moy S, Wei L, Van't Klooster MA, Knight RT, Harper RM, Bragin A, Fried I, Engel J, Staba RJ. Ripples on spikes show increased phase-amplitude coupling in mesial temporal lobe epilepsy seizure-onset zones. Epilepsia. 2016 11; 57(11):1916-1930. PMID: 27723936.
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    36. Reid AY, Bragin A, Giza CC, Staba RJ, Engel J. The progression of electrophysiologic abnormalities during epileptogenesis after experimental traumatic brain injury. Epilepsia. 2016 Oct; 57(10):1558-1567. PMID: 27495360.
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    37. Kerr WT, Janio EA, Le JM, Hori JM, Patel AB, Gallardo NL, Bauirjan J, Chau AM, D'Ambrosio SR, Cho AY, Engel J, Cohen MS, Stern JM. Diagnostic delay in psychogenic seizures and the association with anti-seizure medication trials. Seizure. 2016 Aug; 40:123-6. PMID: 27398686.
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    38. Bragin A, Li L, Almajano J, Alvarado-Rojas C, Reid AY, Staba RJ, Engel J. Pathologic electrographic changes after experimental traumatic brain injury. Epilepsia. 2016 05; 57(5):735-45. PMID: 27012461.
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    39. Engel J. When is temporal lobe epilepsy not temporal lobe epilepsy? Brain. 2016 Feb; 139(Pt 2):309-12. PMID: 26912517.
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    40. Weiss SA, Alvarado-Rojas C, Bragin A, Behnke E, Fields T, Fried I, Engel J, Staba R. Ictal onset patterns of local field potentials, high frequency oscillations, and unit activity in human mesial temporal lobe epilepsy. Epilepsia. 2016 Jan; 57(1):111-21. PMID: 26611159.
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    41. Dewar S, Eliashiv D, Walshaw PD, Engel J, Fried I, Moseley BD. Safety, efficacy, and life satisfaction following epilepsy surgery in patients aged 60 years and older. J Neurosurg. 2016 Apr; 124(4):945-51. PMID: 26381254.
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    42. Jehi L, Friedman D, Carlson C, Cascino G, Dewar S, Elger C, Engel J, Knowlton R, Kuzniecky R, McIntosh A, O'Brien TJ, Spencer D, Sperling MR, Worrell G, Bingaman B, Gonzalez-Martinez J, Doyle W, French J. The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia. Epilepsia. 2015 Oct; 56(10):1526-33. PMID: 26250432.
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    43. Memarian N, Kim S, Dewar S, Engel J, Staba RJ. Multimodal data and machine learning for surgery outcome prediction in complicated cases of mesial temporal lobe epilepsy. Comput Biol Med. 2015 Sep; 64:67-78. PMID: 26149291.
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    44. Chiang S, Stern JM, Engel J, Haneef Z. Structural-functional coupling changes in temporal lobe epilepsy. Brain Res. 2015 Aug 07; 1616:45-57. PMID: 25960346.
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    45. Haneef Z, Chiang S, Yeh HJ, Engel J, Stern JM. Functional connectivity homogeneity correlates with duration of temporal lobe epilepsy. Epilepsy Behav. 2015 May; 46:227-33. PMID: 25873437.
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    46. Memarian N, Madsen SK, Macey PM, Fried I, Engel J, Thompson PM, Staba RJ. Ictal depth EEG and MRI structural evidence for two different epileptogenic networks in mesial temporal lobe epilepsy. PLoS One. 2015; 10(4):e0123588. PMID: 25849340.
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    47. Engel J. Who will use epilepsy surgery nomograms, and why? Lancet Neurol. 2015 Mar; 14(3):240-1. PMID: 25638641.
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    48. Del Brutto OH, Engel J, Eliashiv DS, Salamon N, García HH. Hippocampal sclerosis: the missing link of cysticercosis epileptogenesis? Epilepsia. 2014 Dec; 55(12):2077-8. PMID: 25556345.
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    49. Chiang S, Stern JM, Engel J, Levin HS, Haneef Z. Differences in graph theory functional connectivity in left and right temporal lobe epilepsy. Epilepsy Res. 2014 Dec; 108(10):1770-81. PMID: 25445238.
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    50. Simonato M, Brooks-Kayal AR, Engel J, Galanopoulou AS, Jensen FE, Moshé SL, O'Brien TJ, Pitkanen A, Wilcox KS, French JA. The challenge and promise of anti-epileptic therapy development in animal models. Lancet Neurol. 2014 Sep; 13(9):949-60. PMID: 25127174.
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    51. Engel J, Wiebe S, Radhakrishnan K, Palmini A. Surgical treatment for epilepsy. Neurologisch (Wien). 2013 Sep; 2013:12-14. PMID: 28251073.
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    52. Haneef Z, Lenartowicz A, Yeh HJ, Engel J, Stern JM. Network analysis of the default mode network using functional connectivity MRI in Temporal Lobe Epilepsy. J Vis Exp. 2014 Aug 05; (90):e51442. PMID: 25146174.
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    53. Kerr WT, Hwang ES, Raman KR, Barritt SE, Patel AB, Le JM, Hori JM, Davis EC, Braesch CT, Janio EA, Lau EP, Cho AY, Anderson A, Silverman DH, Salamon N, Engel J, Stern JM, Cohen MS. Multimodal diagnosis of epilepsy using conditional dependence and multiple imputation. Int Workshop Pattern Recognit Neuroimaging. 2014 Jun; 1-4. PMID: 25311448.
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    54. Dedeurwaerdere S, Shultz SR, Federico P, Engel J. Workshop on Neurobiology of Epilepsy appraisal: new systemic imaging technologies to study the brain in experimental models of epilepsy. Epilepsia. 2014 Jun; 55(6):819-28. PMID: 24836499.
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    55. Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J, Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshé SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014 Apr; 55(4):475-82. PMID: 24730690.
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    56. Pitkänen A, Engel J. Past and present definitions of epileptogenesis and its biomarkers. Neurotherapeutics. 2014 Apr; 11(2):231-41. PMID: 24492975.
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    57. Engel J. Approaches to refractory epilepsy. Ann Indian Acad Neurol. 2014 Mar; 17(Suppl 1):S12-7. PMID: 24791078.
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    58. Bragin A, Almajano J, Kheiri F, Engel J. Functional connectivity in the brain estimated by analysis of gamma events. PLoS One. 2014; 9(1):e85900. PMID: 24465774.
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    59. Haneef Z, Lenartowicz A, Yeh HJ, Levin HS, Engel J, Stern JM. Functional connectivity of hippocampal networks in temporal lobe epilepsy. Epilepsia. 2014 Jan; 55(1):137-45. PMID: 24313597.
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    60. Alvarado-Rojas C, Lehongre K, Bagdasaryan J, Bragin A, Staba R, Engel J, Navarro V, Le Van Quyen M. Single-unit activities during epileptic discharges in the human hippocampal formation. Front Comput Neurosci. 2013; 7:140. PMID: 24151464.
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    61. Burneo JG, Sirven JI, Kiesel LW, Vecht CJ, Jehi L, Chung SS, Uhm J, Politsky JM, Chang EF, Husain AM, Tatum WO, Meador KJ, Noe K, Hesdorffer DC, Herman ST, Wiebe S, Engel J, Schrader S, Parko KL, Dichter MA, Kwan P, Kossoff E, Sperling MR. Managing common complex symptomatic epilepsies: tumors and trauma: american epilepsy society - 2012 annual course summary. Epilepsy Curr. 2013 Sep; 13(5):232-5. PMID: 24348117.
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    62. Engel J, Pitkänen A, Loeb JA, Dudek FE, Bertram EH, Cole AJ, Moshé SL, Wiebe S, Jensen FE, Mody I, Nehlig A, Vezzani A. Epilepsy biomarkers. Epilepsia. 2013 Aug; 54 Suppl 4:61-9. PMID: 23909854.
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    63. Korczyn AD, Schachter SC, Brodie MJ, Dalal SS, Engel J, Guekht A, Hecimovic H, Jerbi K, Kanner AM, Johannessen Landmark C, Mares P, Marusic P, Meletti S, Mula M, Patsalos PN, Reuber M, Ryvlin P, Štillová K, Tuchman R, Rektor I. Epilepsy, cognition, and neuropsychiatry (Epilepsy, Brain, and Mind, part 2). Epilepsy Behav. 2013 Aug; 28(2):283-302. PMID: 23764496.
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    64. Rektor I, Schachter SC, Arzy S, Baloyannis SJ, Bazil C, Brázdil M, Engel J, Helmstaedter G, Hesdorffer DC, Jones-Gotman M, Kesner L, Komárek V, Krämer G, Leppik IE, Mann MW, Mula M, Risse GL, Stoker GW, Kasteleijn-Nolst Trenité DG, Trimble M, Tyrliková I, Korczyn AD. Epilepsy, behavior, and art (Epilepsy, Brain, and Mind, part 1). Epilepsy Behav. 2013 Aug; 28(2):261-82. PMID: 23764495.
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    65. Memarian N, Thompson PM, Engel J, Staba RJ. Quantitative analysis of structural neuroimaging of mesial temporal lobe epilepsy. Imaging Med. 2013 Jun 01; 5(3). PMID: 24319498.
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    66. Engel J, Thompson PM, Stern JM, Staba RJ, Bragin A, Mody I. Connectomics and epilepsy. Curr Opin Neurol. 2013 Apr; 26(2):186-94. PMID: 23406911.
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    67. Kheiri F, Bragin A, Engel J. Functional connectivity between brain areas estimated by analysis of gamma waves. J Neurosci Methods. 2013 Apr 15; 214(2):184-91. PMID: 23376499.
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    68. Haneef Z, Lenartowicz A, Yeh HJ, Engel J, Stern JM. Effect of lateralized temporal lobe epilepsy on the default mode network. Epilepsy Behav. 2012 Nov; 25(3):350-7. PMID: 23103309.
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    69. Bateman LM, Begley CE, Ben-Menachem E, Berg AT, Berkovic SF, Cascino GD, Drazkowski J, Edwards JC, Engel J, French JA, Gilliam FD, Hoerth MT, Jehi LE, Kanner AM, Krauss GL, Labiner DM, Loddenkemper T, Luders HO, McKhann GM, McLachlan R, Modi A, Pennell PB, Shafer PO, Sirven JI, Stern JM, Szaflarski JP, Theodore WH. Overcoming barriers to successful epilepsy management. Epilepsy Curr. 2012 Jul; 12(4):158-60. PMID: 22936891.
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    70. Simonato M, Löscher W, Cole AJ, Dudek FE, Engel J, Kaminski RM, Loeb JA, Scharfman H, Staley KJ, Velíšek L, Klitgaard H. Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. Epilepsia. 2012 Nov; 53(11):1860-7. PMID: 22708847.
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    71. Engel J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012 Mar 07; 307(9):922-30. PMID: 22396514.
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    72. Engel J, da Silva FL. High-frequency oscillations - where we are and where we need to go. Prog Neurobiol. 2012 Sep; 98(3):316-8. PMID: 22342736.
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    73. Kheiri F, Bragin A, Engel J, Almajano J, Winden E. Non-linear classification of heart rate parameters as a biomarker for epileptogenesis. Epilepsy Res. 2012 Jun; 100(1-2):59-66. PMID: 22305585.
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    74. Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M. Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia. 2012 Mar; 53(3):571-82. PMID: 22292566.
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    75. Engel J, Wiebe S. Who is a surgical candidate? Handb Clin Neurol. 2012; 108:821-8. PMID: 22939068.
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    76. Engel J, Thompson PM. Going beyond hippocampocentricity in the concept of mesial temporal lobe epilepsy. Epilepsia. 2012 Jan; 53(1):220-3. PMID: 22221162.
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    77. Staba RJ, Ekstrom AD, Suthana NA, Burggren A, Fried I, Engel J, Bookheimer SY. Gray matter loss correlates with mesial temporal lobe neuronal hyperexcitability inside the human seizure-onset zone. Epilepsia. 2012 Jan; 53(1):25-34. PMID: 22126325.
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    78. Engel J. Biomarkers in epilepsy: foreword. Biomark Med. 2011 Oct; 5(5):529-30. PMID: 22003900.
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    79. Engel J. Biomarkers in epilepsy: introduction. Biomark Med. 2011 Oct; 5(5):537-44. PMID: 22003902.
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    80. Cendes F, Engel J. Extending applications for high-frequency oscillations: the ripple effect. Neurology. 2011 Aug 09; 77(6):518-9. PMID: 21753164.
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    81. Winden KD, Karsten SL, Bragin A, Kudo LC, Gehman L, Ruidera J, Geschwind DH, Engel J. A systems level, functional genomics analysis of chronic epilepsy. PLoS One. 2011; 6(6):e20763. PMID: 21695113.
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    82. Engel J. The etiologic classification of epilepsy. Epilepsia. 2011 Jun; 52(6):1195-7; discussion 1205-9. PMID: 21671927.
      View in: PubMed
    83. Engel J. Another good reason to consider surgical treatment for epilepsy more often and sooner. Arch Neurol. 2011 Jun; 68(6):707-8. PMID: 21670394.
      View in: PubMed
    84. Bragin A, Benassi SK, Kheiri F, Engel J. Further evidence that pathologic high-frequency oscillations are bursts of population spikes derived from recordings of identified cells in dentate gyrus. Epilepsia. 2011 Jan; 52(1):45-52. PMID: 21204820.
      View in: PubMed
    85. Engel J. Do we belittle epilepsy by calling it a disorder rather than a disease? Epilepsia. 2010 Nov; 51(11):2363-4. PMID: 21175600.
      View in: PubMed
    86. Engel J, McDermott MP, Wiebe S, Langfitt JT, Erba G, Gardiner I, Stern J, Dewar S, Sperling MR, Jacobs M, Kieburtz K. Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy. Epilepsia. 2010 Oct; 51(10):1978-86. PMID: 20550556.
      View in: PubMed
    87. Haneef Z, Stern J, Dewar S, Engel J. Referral pattern for epilepsy surgery after evidence-based recommendations: a retrospective study. Neurology. 2010 Aug 24; 75(8):699-704. PMID: 20733145.
      View in: PubMed
    88. Bragin A, Engel J, Staba RJ. High-frequency oscillations in epileptic brain. Curr Opin Neurol. 2010 Apr; 23(2):151-6. PMID: 20160649.
      View in: PubMed
    89. Engel J, Akhtari M, Bragin A, Fried I, Ogren JA, Staba RJ, Salamon N, Thompson PM. New approaches to structural and functional imaging in focal epilepsy. Epilepsia. 2010 Feb; 51 Suppl 1:83-6. PMID: 20331726.
      View in: PubMed
    90. Upchurch K, Stern JM, Salamon N, Dewar S, Engel J, Vinters HV, Fried I. Epileptogenic temporal cavernous malformations: operative strategies and postoperative seizure outcomes. Seizure. 2010 Mar; 19(2):120-8. PMID: 20045354.
      View in: PubMed
    91. Ogren JA, Wilson CL, Bragin A, Lin JJ, Salamon N, Dutton RA, Luders E, Fields TA, Fried I, Toga AW, Thompson PM, Engel J, Staba RJ. Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus. Ann Neurol. 2009 Dec; 66(6):783-91. PMID: 20035513.
      View in: PubMed
    92. Engel J, Moshé SL. Commentary: hormones, diet, and botanicals. Neurotherapeutics. 2009 Apr; 6(2):421-3. PMID: 19332339.
      View in: PubMed
    93. Bragin A, Azizyan A, Almajano J, Engel J. The cause of the imbalance in the neuronal network leading to seizure activity can be predicted by the electrographic pattern of the seizure onset. J Neurosci. 2009 Mar 18; 29(11):3660-71. PMID: 19295168.
      View in: PubMed
    94. Engel J. The ILAE --where it was, and where it is going: a personal view. Epilepsia. 2009 Mar; 50(3):343-5. PMID: 19317879.
      View in: PubMed
    95. He DF, Ma DL, Tang YC, Engel J, Bragin A, Tang FR. Morpho-physiologic characteristics of dorsal subicular network in mice after pilocarpine-induced status epilepticus. Brain Pathol. 2010 Jan; 20(1):80-95. PMID: 19298597.
      View in: PubMed
    96. Lerner JT, Salamon N, Hauptman JS, Velasco TR, Hemb M, Wu JY, Sankar R, Donald Shields W, Engel J, Fried I, Cepeda C, Andre VM, Levine MS, Miyata H, Yong WH, Vinters HV, Mathern GW. Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia. 2009 Jun; 50(6):1310-35. PMID: 19175385.
      View in: PubMed
    97. Engel J, Bragin A, Staba R, Mody I. High-frequency oscillations: what is normal and what is not? Epilepsia. 2009 Apr; 50(4):598-604. PMID: 19055491.
      View in: PubMed
    98. Engel J. Surgical treatment for epilepsy: too little, too late? JAMA. 2008 Dec 03; 300(21):2548-50. PMID: 19050199.
      View in: PubMed
    99. Ogren JA, Bragin A, Wilson CL, Hoftman GD, Lin JJ, Dutton RA, Fields TA, Toga AW, Thompson PM, Engel J, Staba RJ. Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns. Epilepsia. 2009 Jun; 50(6):1361-70. PMID: 19054395.
      View in: PubMed
    100. Engel J. More on the history of temporal lobe surgery. Epilepsia. 2008 Aug; 49(8):1481-2. PMID: 18754947.
      View in: PubMed
    101. Le Van Quyen M, Bragin A, Staba R, Crépon B, Wilson CL, Engel J. Cell type-specific firing during ripple oscillations in the hippocampal formation of humans. J Neurosci. 2008 Jun 11; 28(24):6104-10. PMID: 18550752.
      View in: PubMed
    102. Akhtari M, Bragin A, Cohen M, Moats R, Brenker F, Lynch MD, Vinters HV, Engel J. Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy. Epilepsia. 2008 Aug; 49(8):1419-30. PMID: 18479391.
      View in: PubMed
    103. Engel J. Progress in epilepsy: reducing the treatment gap and the promise of biomarkers. Curr Opin Neurol. 2008 Apr; 21(2):150-4. PMID: 18317272.
      View in: PubMed
    104. Avanzini G, Engel J. Dealing with drug dependency: a commentary on ILAE's partnership with the pharmaceutical industry. Epilepsia. 2007 Oct; 48(10):1821-4. PMID: 17683507.
      View in: PubMed
    105. Staba RJ, Frighetto L, Behnke EJ, Mathern GW, Fields T, Bragin A, Ogren J, Fried I, Wilson CL, Engel J. Increased fast ripple to ripple ratios correlate with reduced hippocampal volumes and neuron loss in temporal lobe epilepsy patients. Epilepsia. 2007 Nov; 48(11):2130-8. PMID: 17662059.
      View in: PubMed
    106. Bragin A, Claeys P, Vonck K, Van Roost D, Wilson C, Boon P, Engel J. Analysis of initial slow waves (ISWs) at the seizure onset in patients with drug resistant temporal lobe epilepsy. Epilepsia. 2007 Oct; 48(10):1883-94. PMID: 17559569.
      View in: PubMed
    107. Co JP, Elia M, Engel J, Guerrini R, Mizrahi EM, Moshé SL, Plouin P. Proposal of an algorithm for diagnosis and treatment of neonatal seizures in developing countries. Epilepsia. 2007 Jun; 48(6):1158-64. PMID: 17442012.
      View in: PubMed
    108. Bragin A, Wilson CL, Engel J. Voltage depth profiles of high-frequency oscillations after kainic acid-induced status epilepticus. Epilepsia. 2007; 48 Suppl 5:35-40. PMID: 17910579.
      View in: PubMed
    109. Lin JJ, Salamon N, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Luders E, Toga AW, Engel J, Thompson PM. Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis. Cereb Cortex. 2007 Sep; 17(9):2007-18. PMID: 17088374.
      View in: PubMed
    110. Engel J. Report of the ILAE classification core group. Epilepsia. 2006 Sep; 47(9):1558-68. PMID: 16981873.
      View in: PubMed
    111. Engel J. ILAE classification of epilepsy syndromes. Epilepsy Res. 2006 Aug; 70 Suppl 1:S5-10. PMID: 16822650.
      View in: PubMed
    112. Engel J, Berg A, Andermann F, Avanzini G, Berkovic S, Blume W, Dulac O, van Emde Boas W, Fejerman N, Plouin P, Scheffer I, Seino M, Williamson P, Wolf P. Are epilepsy classifications based on epileptic syndromes and seizure types outdated? Epileptic Disord. 2006 Jun; 8(2):159-60. PMID: 16793579.
      View in: PubMed
    113. Zeitzer JM, Morales-Villagran A, Maidment NT, Behnke EJ, Ackerson LC, Lopez-Rodriguez F, Fried I, Engel J, Wilson CL. Extracellular adenosine in the human brain during sleep and sleep deprivation: an in vivo microdialysis study. Sleep. 2006 Apr; 29(4):455-61. PMID: 16676778.
      View in: PubMed
    114. Bragin A, Azizyan A, Almajano J, Wilson CL, Engel J. Analysis of chronic seizure onsets after intrahippocampal kainic acid injection in freely moving rats. Epilepsia. 2005 Oct; 46(10):1592-8. PMID: 16190929.
      View in: PubMed
    115. Fisher RS, van Emde Boas W, Blume W, Elger C, Genton P, Lee P, Engel J. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia. 2005 Apr; 46(4):470-2. PMID: 15816939.
      View in: PubMed
    116. Bookheimer S, Schrader LM, Rausch R, Sankar R, Engel J. Reduced anesthetization during the intracarotid amobarbital (Wada) test in patients taking carbonic anhydrase-inhibiting medications. Epilepsia. 2005 Feb; 46(2):236-43. PMID: 15679504.
      View in: PubMed
    117. Bragin A, Wilson CL, Fields T, Fried I, Engel J. Analysis of seizure onset on the basis of wideband EEG recordings. Epilepsia. 2005; 46 Suppl 5:59-63. PMID: 15987255.
      View in: PubMed
    118. Schrader LM, Stern JM, Koski L, Nuwer MR, Engel J. Seizure incidence during single- and paired-pulse transcranial magnetic stimulation (TMS) in individuals with epilepsy. Clin Neurophysiol. 2004 Dec; 115(12):2728-37. PMID: 15546781.
      View in: PubMed
    119. Bragin A, Wilson CL, Almajano J, Mody I, Engel J. High-frequency oscillations after status epilepticus: epileptogenesis and seizure genesis. Epilepsia. 2004 Sep; 45(9):1017-23. PMID: 15329064.
      View in: PubMed
    120. Mintzer S, Cendes F, Soss J, Andermann F, Engel J, Dubeau F, Olivier A, Fried I. Unilateral hippocampal sclerosis with contralateral temporal scalp ictal onset. Epilepsia. 2004 Jul; 45(7):792-802. PMID: 15230704.
      View in: PubMed
    121. Staba RJ, Wilson CL, Bragin A, Jhung D, Fried I, Engel J. High-frequency oscillations recorded in human medial temporal lobe during sleep. Ann Neurol. 2004 Jul; 56(1):108-15. PMID: 15236407.
      View in: PubMed
    122. Bragin A, Karsten SL, Almajano J, Wilson CL, Geschwind DH, Engel J. Large-scale microarray gene expression analysis in discrete electrophysiologically identified neuronal clusters. J Neurosci Methods. 2004 Feb 15; 133(1-2):49-55. PMID: 14757344.
      View in: PubMed
    123. Engel J. The goal of epilepsy therapy: no seizures, no side effects, as soon as possible. CNS Spectr. 2004 Feb; 9(2):95-7. PMID: 14999165.
      View in: PubMed
    124. Engel J. Models of focal epilepsy. Suppl Clin Neurophysiol. 2004; 57:392-9. PMID: 16106638.
      View in: PubMed
    125. Engel J, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B. Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Epilepsia. 2003 Jun; 44(6):741-51. PMID: 12790886.
      View in: PubMed
    126. Engel J, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurological Surgeons. Neurology. 2003 Feb 25; 60(4):538-47. PMID: 12601090.
      View in: PubMed
    127. Swarztrauber K, Dewar S, Engel J. Patient attitudes about treatments for intractable epilepsy. Epilepsy Behav. 2003 Feb; 4(1):19-25. PMID: 12609224.
      View in: PubMed
    128. Engel J, Wilson C, Bragin A. Advances in understanding the process of epileptogenesis based on patient material: what can the patient tell us? Epilepsia. 2003; 44 Suppl 12:60-71. PMID: 14641562.
      View in: PubMed
    129. Goldman RI, Stern JM, Engel J, Cohen MS. Simultaneous EEG and fMRI of the alpha rhythm. Neuroreport. 2002 Dec 20; 13(18):2487-92. PMID: 12499854.
      View in: PubMed
    130. Staba RJ, Wilson CL, Bragin A, Fried I, Engel J. Quantitative analysis of high-frequency oscillations (80-500 Hz) recorded in human epileptic hippocampus and entorhinal cortex. J Neurophysiol. 2002 Oct; 88(4):1743-52. PMID: 12364503.
      View in: PubMed
    131. Bragin A, Wilson CL, Staba RJ, Reddick M, Fried I, Engel J. Interictal high-frequency oscillations (80-500 Hz) in the human epileptic brain: entorhinal cortex. Ann Neurol. 2002 Oct; 52(4):407-15. PMID: 12325068.
      View in: PubMed
    132. Staba RJ, Wilson CL, Bragin A, Fried I, Engel J. Sleep states differentiate single neuron activity recorded from human epileptic hippocampus, entorhinal cortex, and subiculum. J Neurosci. 2002 Jul 01; 22(13):5694-704. PMID: 12097521.
      View in: PubMed
    133. Bragin A, Wilson CL, Engel J. Increased afterdischarge threshold during kindling in epileptic rats. Exp Brain Res. 2002 May; 144(1):30-7. PMID: 11976757.
      View in: PubMed
    134. Bragin A, Mody I, Wilson CL, Engel J. Local generation of fast ripples in epileptic brain. J Neurosci. 2002 Mar 01; 22(5):2012-21. PMID: 11880532.
      View in: PubMed
    135. Bragin A, Wilson CL, Engel J. Rate of interictal events and spontaneous seizures in epileptic rats after electrical stimulation of hippocampus and its afferents. Epilepsia. 2002; 43 Suppl 5:81-5. PMID: 12121300.
      View in: PubMed
    136. Engel J. So what can we conclude--do seizures damage the brain? Prog Brain Res. 2002; 135:509-12. PMID: 12143369.
      View in: PubMed
    137. Staba RJ, Wilson CL, Fried I, Engel J. Single neuron burst firing in the human hippocampus during sleep. Hippocampus. 2002; 12(6):724-34. PMID: 12542225.
      View in: PubMed
    138. Engel J. Early versus late surgery for intractable seizures. Adv Exp Med Biol. 2002; 497:99-105. PMID: 11998832.
      View in: PubMed
    139. Engel J. Mesial temporal lobe epilepsy: what have we learned? Neuroscientist. 2001 Aug; 7(4):340-52. PMID: 11488399.
      View in: PubMed
    140. Engel J. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. Epilepsia. 2001 Jun; 42(6):796-803. PMID: 11422340.
      View in: PubMed
    141. Engel J. When is imaging enough? Epileptic Disord. 1999 Dec; 1(4):249-53. PMID: 10937162.
      View in: PubMed
    142. Engel J. The timing of surgical intervention for mesial temporal lobe epilepsy: a plan for a randomized clinical trial. Arch Neurol. 1999 Nov; 56(11):1338-41. PMID: 10555652.
      View in: PubMed
    143. Engel J. Research on the human brain in an epilepsy surgery setting. Epilepsy Res. 1998 Sep; 32(1-2):1-11. PMID: 9761304.
      View in: PubMed