Jide Tian

Title(s)	Adjunct Professor, Molecular and Medical Pharmacology
School	Medicine
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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GABAA-Receptor Agonists Limit Pneumonitis and Death in Murine Coronavirus-Infected Mice. Viruses. 2021 05 23; 13(6). Tian J, Middleton B, Kaufman DL. PMID: 34071034; PMCID: PMC8224554.

View in: PubMed Mentions: 6 Fields:
Vir Virology
Translation:Animals Cells
Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis. Sci Rep. 2021 03 08; 11(1):5402. Tian J, Song M, Kaufman DL. PMID: 33686135; PMCID: PMC7940650.

View in: PubMed Mentions: 5 Fields:
Sci Science
Translation:Animals Cells
GABAB-Receptor Agonist-Based Immunotherapy for Type 1 Diabetes in NOD Mice. Biomedicines. 2021 Jan 06; 9(1). Tian J, Middleton B, Lee VS, Park HW, Zhang Z, Kim B, Lowe C, Nguyen N, Liu H, Beyer RS, Chao HW, Chen R, Mai D, O'Laco KA, Song M, Kaufman DL. PMID: 33418884; PMCID: PMC7825043.

View in: PubMed Mentions: 3
GABA administration prevents severe illness and death following coronavirus infection in mice. bioRxiv. 2020 Oct 04. Tian J, Middleton B, Kaufman DL. PMID: 33024975; PMCID: PMC7536896.

View in: PubMed Mentions:
Homotaurine Treatment Enhances CD4+ and CD8+ Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice. Immunohorizons. 2019 10 21; 3(10):498-510. Tian J, Dang H, O'Laco KA, Song M, Tiu BC, Gilles S, Zakarian C, Kaufman DL. PMID: 31636084; PMCID: PMC6823932.

View in: PubMed Mentions: 9 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. Sci Rep. 2019 03 12; 9(1):4269. Yong J, Tian J, Dang H, Wu TT, Atkinson MA, Sun R, Kaufman DL. PMID: 30862859; PMCID: PMC6414670.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Humans Animals Cells
A Clinically Applicable Positive Allosteric Modulator of GABA Receptors Promotes Human β-Cell Replication and Survival as well as GABA's Ability to Inhibit Inflammatory T Cells. J Diabetes Res. 2019; 2019:5783545. Tian J, Dang H, Karashchuk N, Xu I, Kaufman DL. PMID: 30937314; PMCID: PMC6413367.

View in: PubMed Mentions: 9 Fields:
End Endocrinology
Translation:Humans Animals Cells
Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis. Sci Rep. 2018 11 08; 8(1):16555. Tian J, Dang H, Wallner M, Olsen R, Kaufman DL. PMID: 30410049; PMCID: PMC6224391.

View in: PubMed Mentions: 14 Fields:
Sci Science
Translation:Animals Cells
Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication. J Diabetes Res. 2017; 2017:6403539. Tian J, Dang H, Hu A, Xu W, Kaufman DL. PMID: 29018828; PMCID: PMC5605788.

View in: PubMed Mentions: 3 Fields:
End Endocrinology
Translation:Humans Animals Cells
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. Sci Rep. 2017 03 23; 7(1):374. Tian J, Dang H, Middleton B, Kaufman DL. PMID: 28336918; PMCID: PMC5428733.

View in: PubMed Mentions: 10 Fields:
Sci Science
Translation:Humans Animals Cells
Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice. Diabetes. 2014 Sep; 63(9):3128-34. Tian J, Dang H, Nguyen AV, Chen Z, Kaufman DL. PMID: 25146474; PMCID: PMC4141368.

View in: PubMed Mentions: 21 Fields:
End Endocrinology
Translation:Animals Cells
γ-Aminobutyric acid regulates both the survival and replication of human β-cells. Diabetes. 2013 Nov; 62(11):3760-5. Tian J, Dang H, Chen Z, Guan A, Jin Y, Atkinson MA, Kaufman DL. PMID: 23995958; PMCID: PMC3806626.

View in: PubMed Mentions: 46 Fields:
End Endocrinology
Translation:Humans Animals Cells
Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci Res. 2013 Oct; 91(10):1292-302. Lacan G, Dang H, Middleton B, Horwitz MA, Tian J, Melega WP, Kaufman DL. PMID: 23907992; PMCID: PMC5800426.

View in: PubMed Mentions: 17 Fields:
Neu Neurology
Translation:Animals Cells
Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization. J Neuroimmunol. 2012 Jun 15; 247(1-2):1-8. Bilousova T, Dang H, Xu W, Gustafson S, Jin Y, Wickramasinghe L, Won T, Bobarnac G, Middleton B, Tian J, Kaufman DL. PMID: 22503373; PMCID: PMC5776040.

View in: PubMed Mentions: 20 Fields:
All Allergy and Immunology Neu Neurology
Translation:Animals Cells
Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. PLoS One. 2011; 6(9):e25338. Tian J, Dang HN, Yong J, Chui WS, Dizon MP, Yaw CK, Kaufman DL. PMID: 21966503; PMCID: PMC3178643.

View in: PubMed Mentions: 55 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ß-cells in diabetic NOD mice. PLoS One. 2011; 6(9):e25337. Tian J, Dang H, Kaufman DL. PMID: 21966502; PMCID: PMC3178649.

View in: PubMed Mentions: 20 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals
Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis. Autoimmunity. 2011 Sep; 44(6):465-70. Tian J, Yong J, Dang H, Kaufman DL. PMID: 21604972; PMCID: PMC5787624.

View in: PubMed Mentions: 47 Fields:
All Allergy and Immunology
Translation:Animals Cells
A potential role for shed soluble major histocompatibility class I molecules as modulators of neurite outgrowth. PLoS One. 2011 Mar 31; 6(3):e18439. Washburn LR, Zekzer D, Eitan S, Lu Y, Dang H, Middleton B, Evans CJ, Tian J, Kaufman DL. PMID: 21483793; PMCID: PMC3069096.

View in: PubMed Mentions: 17 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes. Diabetes. 2011 May; 60(5):1383-92. Yong J, Rasooly J, Dang H, Lu Y, Middleton B, Zhang Z, Hon L, Namavari M, Stout DB, Atkinson MA, Tian J, Gambhir SS, Kaufman DL. PMID: 21441442; PMCID: PMC3292311.

View in: PubMed Mentions: 16 Fields:
End Endocrinology
Translation:Animals Cells
BCG vaccine-induced neuroprotection in a mouse model of Parkinson's disease. PLoS One. 2011 Jan 31; 6(1):e16610. Yong J, Lacan G, Dang H, Hsieh T, Middleton B, Wasserfall C, Tian J, Melega WP, Kaufman DL. PMID: 21304945; PMCID: PMC3031604.

View in: PubMed Mentions: 14 Fields:
Med Medicine (General)Sci Science
Translation:Animals PHPublic Health
Major histocompatibility complex class I-mediated inhibition of neurite outgrowth from peripheral nerves. Immunol Lett. 2011 Mar 30; 135(1-2):118-23. Wu ZP, Bilousova T, Escande-Beillard N, Dang H, Hsieh T, Tian J, Kaufman DL. PMID: 20974178; PMCID: PMC5776043.

View in: PubMed Mentions: 11 Fields:
All Allergy and Immunology
Translation:Animals Cells
Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair. J Neuroimmunol. 2011 Mar; 232(1-2):8-16. Wu ZP, Washburn L, Bilousova TV, Boudzinskaia M, Escande-Beillard N, Querubin J, Dang H, Xie CW, Tian J, Kaufman DL. PMID: 20950866; PMCID: PMC5776042.

View in: PubMed Mentions: 17 Fields:
All Allergy and Immunology Neu Neurology
Translation:Animals Cells
Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented. J Immunol. 2010 Jan 15; 184(2):816-23. Escande-Beillard N, Washburn L, Zekzer D, Wu ZP, Eitan S, Ivkovic S, Lu Y, Dang H, Middleton B, Bilousova TV, Yoshimura Y, Evans CJ, Joyce S, Tian J, Kaufman DL. PMID: 20018625; PMCID: PMC2997386.

View in: PubMed Mentions: 16 Fields:
All Allergy and Immunology
Translation:Animals Cells
Transgenically induced GAD tolerance curtails the development of early beta-cell autoreactivities but causes the subsequent development of supernormal autoreactivities to other beta-cell antigens. Diabetes. 2009 Dec; 58(12):2843-50. Tian J, Dang H, von Boehmer H, Jaeckel E, Kaufman DL. PMID: 19741165; PMCID: PMC2780885.

View in: PubMed Mentions: 5 Fields:
End Endocrinology
Translation:Animals Cells
Antigen-based therapy for the treatment of type 1 diabetes. Diabetes. 2009 Sep; 58(9):1939-46. Tian J, Kaufman DL. PMID: 19720821; PMCID: PMC2731536.

View in: PubMed Mentions: 18 Fields:
End Endocrinology
Translation:Humans Animals
Long-term monitoring of transplanted islets using positron emission tomography. Mol Ther. 2006 Dec; 14(6):851-6. Lu Y, Dang H, Middleton B, Campbell-Thompson M, Atkinson MA, Gambhir SS, Tian J, Kaufman DL. PMID: 16982215.

View in: PubMed Mentions: 16 Fields:
Mol Molecular Biology The Therapeutics
Translation:Humans Animals Cells
Noninvasive imaging of islet grafts using positron-emission tomography. Proc Natl Acad Sci U S A. 2006 Jul 25; 103(30):11294-9. Lu Y, Dang H, Middleton B, Zhang Z, Washburn L, Stout DB, Campbell-Thompson M, Atkinson MA, Phelps M, Gambhir SS, Tian J, Kaufman DL. PMID: 16868090; PMCID: PMC1544080.

View in: PubMed Mentions: 20 Fields:
Sci Science
Translation:Humans Animals Cells
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol. 2006 Apr; 26(7):2772-81. Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H. PMID: 16537919; PMCID: PMC1430339.

View in: PubMed Mentions: 67 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Animals Cells
B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice. J Immunol. 2006 Feb 15; 176(4):2654-61. Tian J, Zekzer D, Lu Y, Dang H, Kaufman DL. PMID: 16456028.

View in: PubMed Mentions: 24 Fields:
All Allergy and Immunology
Translation:Animals Cells PHPublic Health
Antigen-based therapies using ignored determinants of beta cell antigens can more effectively inhibit late-stage autoimmune disease in diabetes-prone mice. J Immunol. 2005 Aug 01; 175(3):1991-9. Olcott AP, Tian J, Walker V, Dang H, Middleton B, Adorini L, Washburn L, Kaufman DL. PMID: 16034144.

View in: PubMed Mentions: 17 Fields:
All Allergy and Immunology
Translation:Animals Cells
Gamma-aminobutyric acid inhibits T cell autoimmunity and the development of inflammatory responses in a mouse type 1 diabetes model. J Immunol. 2004 Oct 15; 173(8):5298-304. Tian J, Lu Y, Zhang H, Chau CH, Dang HN, Kaufman DL. PMID: 15470076.

View in: PubMed Mentions: 90 Fields:
All Allergy and Immunology
Translation:Animals Cells
A salen-manganese catalytic free radical scavenger inhibits type 1 diabetes and islet allograft rejection. Diabetes. 2004 Oct; 53(10):2574-80. Olcott AP, Tocco G, Tian J, Zekzer D, Fukuto J, Ignarro L, Kaufman DL. PMID: 15448086.

View in: PubMed Mentions: 6 Fields:
End Endocrinology
Translation:Animals Cells
Bioluminescent monitoring of islet graft survival after transplantation. Mol Ther. 2004 Mar; 9(3):428-35. Lu Y, Dang H, Middleton B, Zhang Z, Washburn L, Campbell-Thompson M, Atkinson MA, Gambhir SS, Tian J, Kaufman DL. PMID: 15006610.

View in: PubMed Mentions: 35 Fields:
Mol Molecular Biology The Therapeutics
Translation:Humans Animals Cells
Memory and effector T cells modulate subsequently primed immune responses to unrelated antigens. Cell Immunol. 2003 Aug; 224(2):74-85. Tian J, Lu Y, Hanssen L, Dang H, Kaufman DL. PMID: 14609573.

View in: PubMed Mentions: 3 Fields:
All Allergy and Immunology Cel Cell Biology
Translation:Animals Cells
Antigen-based immunotherapy drives the precocious development of autoimmunity. J Immunol. 2002 Dec 01; 169(11):6564-9. Tian J, Olcott AP, Kaufman DL. PMID: 12444168.

View in: PubMed Mentions: 11 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice. J Immunol. 2001 Jul 15; 167(2):1081-9. Tian J, Zekzer D, Hanssen L, Lu Y, Olcott A, Kaufman DL. PMID: 11441119.

View in: PubMed Mentions: 145 Fields:
All Allergy and Immunology
Translation:Animals Cells