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Chute, John P

Title(s)Professor, Medicine
SchoolMed - Hematology And Oncology
Phone3102063037
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    Other Positions
    Title(s)Professor, Orthopaedic Surgery

    Title(s)Professor, Radiation Oncology


    Collapse Research 
    Collapse Research Activities and Funding
    Epidermal growth factor mitigates radiation-induced hematopoietic failure
    NIH/NIAID U01AI107333May 15, 2013 - Apr 30, 2018
    Role: Principal Investigator
    Semaphorin signaling regulates vascular and hematopoietic regeneration
    NIH/NHLBI R01HL086998Aug 15, 2008 - Nov 30, 2022
    Role: Principal Investigator
    The UCLA Center for Medical Countermeasures Against Radiation
    NIH/NIAID U19AI067769Aug 31, 2005 - Jul 31, 2020
    Role: Co-Principal Investigator
    Academic Training in Hematology
    NIH/NHLBI T32HL066992Aug 1, 2001 - Jun 30, 2012
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020 Jan 02; 130(1):315-328. PMID: 31613796.
      View in: PubMed
    2. Chute JP, Termini CM. Mutualism in the Marrow. Cell Stem Cell. 2019 Dec 05; 25(6):731-733. PMID: 31809734.
      View in: PubMed
    3. Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. PTPs inhibitors promote hematopoietic stem cell regeneration. Nat Commun. 2019 08 14; 10(1):3667. PMID: 31413255.
      View in: PubMed
    4. Chute JP. Autologous Stem Cell Transplantation for Multiple Myeloma: Underutilized but Highly Effective. J Natl Cancer Inst. 2019 Jan 01; 111(1):7-8. PMID: 29897483.
      View in: PubMed
    5. Himburg HA, Termini CM, Schlussel L, Kan J, Li M, Zhao L, Fang T, Sasine JP, Chang VY, Chute JP. Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. Cell Stem Cell. 2018 09 06; 23(3):370-381.e5. PMID: 30100167.
      View in: PubMed
    6. Sasine JP, Himburg HA, Termini CM, Roos M, Tran E, Zhao L, Kan J, Li M, Zhang Y, de Barros SC, Rao DS, Counter CM, Chute JP. Wild-type Kras expands and exhausts hematopoietic stem cells. JCI Insight. 2018 06 07; 3(11). PMID: 29875320.
      View in: PubMed
    7. Chang VY, Termini CM, Chute JP. Young endothelial cells revive aging blood. J Clin Invest. 2017 11 01; 127(11):3921-3922. PMID: 29035281.
      View in: PubMed
    8. Chai-Ho W, Chute JP. Paracrine regulation of normal and malignant hematopoiesis. Curr Opin Hematol. 2017 Jul; 24(4):329-335. PMID: 28594661.
      View in: PubMed
    9. Himburg HA, Doan PL, Quarmyne M, Yan X, Sasine J, Zhao L, Hancock GV, Kan J, Pohl KA, Tran E, Chao NJ, Harris JR, Chute JP. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat Med. 2017 01; 23(1):91-99. PMID: 27918563.
      View in: PubMed
    10. Yan X, Himburg HA, Pohl K, Quarmyne M, Tran E, Zhang Y, Fang T, Kan J, Chao NJ, Zhao L, Doan PL, Chute JP. Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. Cell Rep. 2016 11 01; 17(6):1584-1594. PMID: 27806297.
      View in: PubMed
    11. Sasine JP, Yeo KT, Chute JP. Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell Fate. Stem Cells Transl Med. 2017 02; 6(2):482-489. PMID: 28191767.
      View in: PubMed
    12. Kanda J, Long GD, Gasparetto C, Horwitz ME, Sullivan KM, Chute JP, Morris A, Shafique M, Li Z, Chao NJ, Rizzieri DA. Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic malignancies. Biol Blood Marrow Transplant. 2014 Feb; 20(2):257-63. PMID: 24269380.
      View in: PubMed
    13. Kanda J, Rizzieri DA, Gasparetto C, Long GD, Chute JP, Sullivan KM, Morris A, Smith CA, Hogge DE, Nitta J, Song K, Niedzwiecki D, Chao NJ, Horwitz ME. Adult dual umbilical cord blood transplantation using myeloablative total body irradiation (1350 cGy) and fludarabine conditioning. Biol Blood Marrow Transplant. 2011 Jun; 17(6):867-74. PMID: 20868761.
      View in: PubMed