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John P Chute

Title(s)Professor, Medicine
SchoolMedicine
Address760 Westwood Plaza 410E
Los Angeles CA 90024
Phone3102063037
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    Other Positions
    Title(s)Professor, Orthopaedic Surgery

    Title(s)Professor, Radiation Oncology


    Collapse Research 
    Collapse Research Activities and Funding
    Mitigation of Radiation Injury via Vascular Regeneration and Remodeling
    NIH U01AI156922Jun 5, 2020 - May 31, 2025
    Role: Principal Investigator
    Epidermal growth factor mitigates radiation-induced hematopoietic failure
    NIH U01AI107333May 15, 2013 - Apr 30, 2018
    Role: Principal Investigator
    Semaphorin signaling regulates vascular and hematopoietic regeneration
    NIH R01HL086998Aug 15, 2008 - Dec 31, 2018
    Role: Principal Investigator
    The UCLA Center for Medical Countermeasures Against Radiation
    NIH U19AI067769Aug 31, 2005 - Aug 31, 2010
    Role: Co-Principal Investigator
    Academic Training in Hematology
    NIH T32HL066992Jul 1, 2001 - Jul 31, 2018
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Proteoglycans regulate protein tyrosine phosphatase receptor s organization on hematopoietic stem/progenitor cells. Exp Hematol. 2021 Jan 27. Termini CM, Pang A, Batton DM, Chute JP. PMID: 33515635.
      View in: PubMed   Mentions: 1     Fields:    
    2. Epidermal growth factor receptor-dependent DNA repair promotes murine and human hematopoietic regeneration. Blood. 2020 Jul 23; 136(4):441-454. Fang T, Zhang Y, Chang VY, Roos M, Termini CM, Signaevskaia L, Quarmyne M, Lin PK, Pang A, Kan J, Yan X, Javier A, Pohl K, Zhao L, Scott P, Himburg HA, Chute JP. PMID: 32369572.
      View in: PubMed   Mentions:    Fields:    
    3. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020 01 02; 130(1):315-328. Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP. PMID: 31613796.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Mutualism in the Marrow. Cell Stem Cell. 2019 12 05; 25(6):731-733. Chute JP, Termini CM. PMID: 31809734.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. PTPs inhibitors promote hematopoietic stem cell regeneration. Nat Commun. 2019 08 14; 10(1):3667. Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. PMID: 31413255.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Autologous Stem Cell Transplantation for Multiple Myeloma: Underutilized but Highly Effective. J Natl Cancer Inst. 2019 01 01; 111(1):7-8. Chute JP. PMID: 29897483.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. Cell Stem Cell. 2018 09 06; 23(3):370-381.e5. Himburg HA, Termini CM, Schlussel L, Kan J, Li M, Zhao L, Fang T, Sasine JP, Chang VY, Chute JP. PMID: 30100167.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    8. Wild-type Kras expands and exhausts hematopoietic stem cells. JCI Insight. 2018 06 07; 3(11). Sasine JP, Himburg HA, Termini CM, Roos M, Tran E, Zhao L, Kan J, Li M, Zhang Y, de Barros SC, Rao DS, Counter CM, Chute JP. PMID: 29875320.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. Young endothelial cells revive aging blood. J Clin Invest. 2017 11 01; 127(11):3921-3922. Chang VY, Termini CM, Chute JP. PMID: 29035281.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    10. Paracrine regulation of normal and malignant hematopoiesis. Curr Opin Hematol. 2017 Jul; 24(4):329-335. Chai-Ho W, Chute JP. PMID: 28594661.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat Med. 2017 01; 23(1):91-99. Himburg HA, Doan PL, Quarmyne M, Yan X, Sasine J, Zhao L, Hancock GV, Kan J, Pohl KA, Tran E, Chao NJ, Harris JR, Chute JP. PMID: 27918563.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCellsPHPublic Health
    12. Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. Cell Rep. 2016 11 01; 17(6):1584-1594. Yan X, Himburg HA, Pohl K, Quarmyne M, Tran E, Zhang Y, Fang T, Kan J, Chao NJ, Zhao L, Doan PL, Chute JP. PMID: 27806297.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell Fate. Stem Cells Transl Med. 2017 02; 6(2):482-489. Sasine JP, Yeo KT, Chute JP. PMID: 28191767.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    14. Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic malignancies. Biol Blood Marrow Transplant. 2014 Feb; 20(2):257-63. Kanda J, Long GD, Gasparetto C, Horwitz ME, Sullivan KM, Chute JP, Morris A, Shafique M, Li Z, Chao NJ, Rizzieri DA. PMID: 24269380.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Adult dual umbilical cord blood transplantation using myeloablative total body irradiation (1350 cGy) and fludarabine conditioning. Biol Blood Marrow Transplant. 2011 Jun; 17(6):867-74. Kanda J, Rizzieri DA, Gasparetto C, Long GD, Chute JP, Sullivan KM, Morris A, Smith CA, Hogge DE, Nitta J, Song K, Niedzwiecki D, Chao NJ, Horwitz ME. PMID: 20868761.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
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