Jonathan D Kaunitz

Title(s)Professor-in-Residence, Medicine
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    Other Positions
    Title(s)Professor-in-Residence, Surgery

    Collapse Research 
    Collapse Research Activities and Funding
    Luminal Factors Affecting Duodenal Protection and Chemosensing
    NIH I01BX001245Jul 1, 2012 - Jun 30, 2021
    Role: Principal Investigator
    An in vitro system for the study of epithelial bicarbonate secretion
    NIH R21DK081199Jun 1, 2009 - May 31, 2012
    Role: Principal Investigator
    Duodenal Mucosal Defense Mechanisms
    NIH R01DK054221May 1, 1999 - Mar 31, 2018
    Role: Principal Investigator
    NIH R01DK039162Sep 18, 1987 - Jun 30, 1992
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Short-chain fatty acid receptors involved in epithelial acetylcholine release in rat caecum. Eur J Pharmacol. 2021 Sep 05; 906:174292. Ballout J, Akiba Y, Kaunitz JD, Diener M. PMID: 34216575.
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    2. DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk. J Clin Invest. 2021 May 03; 131(9). Grasberger H, Magis AT, Sheng E, Conomos MP, Zhang M, Garzotto LS, Hou G, Bishu S, Nagao-Kitamoto H, El-Zaatari M, Kitamoto S, Kamada N, Stidham RW, Akiba Y, Kaunitz J, Haberman Y, Kugathasan S, Denson LA, Omenn GS, Kao JY. PMID: 33651715.
      View in: PubMed   Mentions: 1     Fields:    
    3. DDS: A Decade of Distinguished Scholarship. Dig Dis Sci. 2021 May; 66(5):1375-1379. Kaunitz JD, Keeffe M. PMID: 32504352.
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    4. Casting a Wider NET: Is It Crohn's or Is It Neuroendocrine Tumor? Dig Dis Sci. 2021 Jun; 66(6):1802-1806. Jeon Y, Leung D, Lis CA, Wang HL, Deurdulian C, Mandelkern M, Kaunitz JD. PMID: 33783690.
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    5. AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia. Gastroenterology. 2021 Jul; 161(1):362-365. Kaunitz JD, Ganz T. PMID: 33675744.
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    6. Welcome Associate Editors Surinder Singh Rana and Rupjyoti Talukdar. Dig Dis Sci. 2021 Mar; 66(3):655-656. Kaunitz JD. PMID: 33428041.
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    7. Welcome Associate Editors Andrew Stewart Day and Hiromu Suzuki. Dig Dis Sci. 2021 02; 66(2):329-330. Kaunitz JD. PMID: 33428038.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Duodenal chemosensory system: enterocytes, enteroendocrine cells, and tuft cells. Curr Opin Gastroenterol. 2020 11; 36(6):501-508. Akiba Y, Hashimoto S, Kaunitz JD. PMID: 32925177.
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    9. PowerPoint to the People: The Four Secrets to Delivering a Great Medical Talk. Dig Dis Sci. 2020 07; 65(7):1892-1894. Zhornitskiy A, Nguyen A, Kaunitz JD. PMID: 32335817.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Conquering COVID-19: How DDS Is CoVering the Pandemic. Dig Dis Sci. 2020 07; 65(7):1873. Kaunitz JD. PMID: 32504348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    11. Impacting Underserved Communities as a GI Trainee. Dig Dis Sci. 2020 06; 65(6):1596-1598. Zhornitskiy A, Nguyen A, Kaunitz J. PMID: 32274667.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Lipopolysaccharides transport during fat absorption in rodent small intestine. Am J Physiol Gastrointest Liver Physiol. 2020 06 01; 318(6):G1070-G1087. Akiba Y, Maruta K, Takajo T, Narimatsu K, Said H, Kato I, Kuwahara A, Kaunitz JD. PMID: 32390462.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    13. The "Leaky Gut": Tight Junctions but Loose Associations? Dig Dis Sci. 2020 05; 65(5):1277-1287. Hollander D, Kaunitz JD. PMID: 31471860.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Correction to: Control of Intestinal Epithelial Proliferation and Differentiation: The Microbiome, Enteroendocrine L Cells, Telocytes, Enteric Nerves, and GLP, Too. Dig Dis Sci. 2020 Feb; 65(2):669. Kaunitz JD, Akiba Y. PMID: 31823102.
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    15. Oral Defense: How Oral Rehydration Solutions Revolutionized the Treatment of Toxigenic Diarrhea. Dig Dis Sci. 2020 02; 65(2):345-348. Kaunitz JD. PMID: 31900719.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    16. GLP-2 Acutely Prevents Endotoxin-Related Increased Intestinal Paracellular Permeability in Rats. Dig Dis Sci. 2020 09; 65(9):2605-2618. Maruta K, Takajo T, Akiba Y, Said H, Irie E, Kato I, Kuwahara A, Kaunitz JD. PMID: 32006214.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin-Induced Diarrhea. J Infect Dis. 2019 10 22; 220(11):1719-1728. Fenton RA, Murali SK, Kaji I, Akiba Y, Kaunitz JD, Kristensen TB, Poulsen SB, Dominguez Rieg JA, Rieg T. PMID: 30624615.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Control of Intestinal Epithelial Proliferation and Differentiation: The Microbiome, Enteroendocrine L Cells, Telocytes, Enteric Nerves, and GLP, Too. Dig Dis Sci. 2019 10; 64(10):2709-2716. Kaunitz JD, Akiba Y. PMID: 31435858.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    19. Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. F1000Res. 2019; 8. Iwasaki M, Akiba Y, Kaunitz JD. PMID: 31559013.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    20. Deficient Active Transport Activity in Healing Mucosa After Mild Gastric Epithelial Damage. Dig Dis Sci. 2020 01; 65(1):119-131. Matthis AL, Kaji I, Engevik KA, Akiba Y, Kaunitz JD, Montrose MH, Aihara E. PMID: 31515722.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    21. Introduction to "DDS Citation Classics": Reaping Dividends from Rising Interest. Dig Dis Sci. 2019 09; 64(9):2384. Kaunitz JD. PMID: 31346951.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. DDS-SIRC Collaboration: L'Inizio di una Bella Amicizia. Dig Dis Sci. 2019 08; 64(8):2113. D'Andrea V, Marino I, Kaunitz JD. PMID: 31190202.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Duodenal Chemosensing of Short-Chain Fatty Acids: Implications for GI Diseases. Curr Gastroenterol Rep. 2019 Jul 10; 21(8):35. Iwasaki M, Akiba Y, Kaunitz JD. PMID: 31289927.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Duodenal chemosensing. Curr Opin Gastroenterol. 2018 11; 34(6):422-427. Iwasaki M, Akiba Y, Kaunitz JD. PMID: 30124472.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe. 2018 06 13; 23(6):775-785.e5. Bhattarai Y, Williams BB, Battaglioli EJ, Whitaker WR, Till L, Grover M, Linden DR, Akiba Y, Kandimalla KK, Zachos NC, Kaunitz JD, Sonnenburg JL, Fischbach MA, Farrugia G, Kashyap PC. PMID: 29902441.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    26. Magnetic Resonance Imaging: The Nuclear Option. Dig Dis Sci. 2018 May; 63(5):1100-1101. Kaunitz JD. PMID: 29497905.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. A Tribute to Paul H. Guth, MD (1927-2017). Dig Dis Sci. 2018 Apr; 63(4):807-810. Kaunitz JD, Akiba Y. PMID: 29464586.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. High quality of cancer care in the Department of Veterans Affairs (VA). Am J Cancer Res. 2018; 8(4):761-762. May FP, Yu C, Kaunitz J. PMID: 29736320.
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    29. [Duodenal mucosal defense mechanisms;Current update on 'Duodenology']. Nihon Shokakibyo Gakkai Zasshi. 2018; 115(2):137-159. Akiba Y, Kaunitz JD. PMID: 29459558.
      View in: PubMed   Mentions:    Fields:    
    30. Luminal chemosensing in the gastroduodenal mucosa. Curr Opin Gastroenterol. 2017 Nov; 33(6):439-445. Kaji I, Kaunitz JD. PMID: 28806271.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    31. FFA2 activation combined with ulcerogenic COX inhibition induces duodenal mucosal injury via the 5-HT pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2017 Aug 01; 313(2):G117-G128. Akiba Y, Maruta K, Narimatsu K, Said H, Kaji I, Kuri A, Iwamoto KI, Kuwahara A, Kaunitz JD. PMID: 28526687.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    32. FFA3 Activation Stimulates Duodenal Bicarbonate Secretion and Prevents NSAID-Induced Enteropathy via the GLP-2 Pathway in Rats. Dig Dis Sci. 2017 08; 62(8):1944-1952. Said H, Akiba Y, Narimatsu K, Maruta K, Kuri A, Iwamoto KI, Kuwahara A, Kaunitz JD. PMID: 28523577.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    33. Development of Monoclonal Antibodies: The Dawn of mAb Rule. Dig Dis Sci. 2017 04; 62(4):831-832. Kaunitz JD. PMID: 28181099.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    34. Xenin Augments Duodenal Anion Secretion via Activation of Afferent Neural Pathways. J Pharmacol Exp Ther. 2017 04; 361(1):151-161. Kaji I, Akiba Y, Kato I, Maruta K, Kuwahara A, Kaunitz JD. PMID: 28115552.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    35. Gastrointestinal defense mechanisms. Curr Opin Gastroenterol. 2016 11; 32(6):461-466. Said H, Kaunitz JD. PMID: 27653163.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Welcome Associate Editors Ajay Goel, Aida Habtezion, and Walter Park. Dig Dis Sci. 2016 11; 61(11):3093-3094. Kaunitz JD. PMID: 27696096.
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    37. Gut chemosensing: implications for disease pathogenesis. F1000Res. 2016; 5:2424. Berg CJ, Kaunitz JD. PMID: 27781093.
      View in: PubMed   Mentions: 3     Fields:    
    38. DDS Elementary Style: A Brief Guide for Authors. Dig Dis Sci. 2016 08; 61(8):2147-2150. Kaunitz JD. PMID: 27312030.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterol Motil. 2016 Nov; 28(11):1663-1676. Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. PMID: 27259385.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    40. CFTR and pHi regulation. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1183. Akiba Y, Kaunitz JD, Montrose MH. PMID: 27281734.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    41. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. J Physiol. 2016 06 15; 594(12):3339-52. Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. PMID: 26854275.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. The Doppler Effect: A Century from Red Shift to Red Spot. Dig Dis Sci. 2016 Feb; 61(2):340-1. Kaunitz JD. PMID: 26745970.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. Gastroduodenal mucosal defense mechanisms. Curr Opin Gastroenterol. 2015 Nov; 31(6):486-91. Said H, Kaji I, Kaunitz JD. PMID: 26376476.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    44. Bugs, genes, fatty acids, and serotonin: Unraveling inflammatory bowel disease? F1000Res. 2015; 4. Kaunitz J, Nayyar P. PMID: 27508055.
      View in: PubMed   Mentions: 1     Fields:    
    45. Compounded bioidentical hormone therapy: time for a reality check? Menopause. 2015 Sep; 22(9):919-20. Kaunitz AM, Kaunitz JD. PMID: 26035149.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. The Discovery of PCR: ProCuRement of Divine Power. Dig Dis Sci. 2015 Aug; 60(8):2230-1. Kaunitz JD. PMID: 26077976.
      View in: PubMed   Mentions: 1     Fields:    
    47. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. J Gastroenterol Hepatol. 2015 Mar; 30 Suppl 1:60-5. Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. PMID: 25827806.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    48. CRC screening, past, present, and future: a tribute to Emmet Keeffe. Dig Dis Sci. 2015 Mar; 60(3):589-91. Ahnen DJ, Bresalier RS, Levin B, Kaunitz JD. PMID: 25724168.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    49. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Dig Dis Sci. 2015 Apr; 60(4):858-67. Akiba Y, Kaunitz JD, Million M. PMID: 25701320.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    50. Short-chain fatty acid sensing in rat duodenum. J Physiol. 2015 Feb 01; 593(3):585-99. Akiba Y, Inoue T, Kaji I, Higashiyama M, Narimatsu K, Iwamoto K, Watanabe M, Guth PH, Engel E, Kuwahara A, Kaunitz JD. PMID: 25433076.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    51. Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration. J Clin Biochem Nutr. 2015 Mar; 56(2):155-62. Fujiwara K, Inoue T, Yorifuji N, Iguchi M, Sakanaka T, Narabayashi K, Kakimoto K, Nouda S, Okada T, Ishida K, Abe Y, Masuda D, Takeuchi T, Fukunishi S, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. PMID: 25759522.
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    52. Prostaglandin pathways in duodenal chemosensing. J Gastroenterol Hepatol. 2014 Dec; 29 Suppl 4:93-8. Akiba Y, Kaunitz JD. PMID: 25521740.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    53. SCFA transport in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 01; 308(3):G188-97. Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 25394661.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    54. The fruits of fiber: the invention of the flexible fiberoptic gastroscope. Dig Dis Sci. 2014 Nov; 59(11):2616-8. Kaunitz JD. PMID: 25193388.
      View in: PubMed   Mentions: 1     Fields:    
    55. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2014 Nov; 30(6):583-8. Kemmerly T, Kaunitz JD. PMID: 25229259.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    56. Introduction to the "GRG profiles and perspectives" series. Dig Dis Sci. 2014 Sep; 59(9):2032. Kaunitz JD, Souza RF. PMID: 25073957.
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    57. Duodenal luminal nutrient sensing. Curr Opin Pharmacol. 2014 Dec; 19:67-75. Rønnestad I, Akiba Y, Kaji I, Kaunitz JD. PMID: 25113991.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    58. Priming the (proton) pump. Dig Dis Sci. 2014 Jul; 59(7):1356-7. Kaunitz JD. PMID: 24627261.
      View in: PubMed   Mentions: 1     Fields:    
    59. Paradigm shifts in perspective III: the discovery of tumor necrosis factor. Dig Dis Sci. 2014 Apr; 59(4):710-1. Kaunitz JD. PMID: 24557574.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Duodenal luminal chemosensing; acid, ATP, and nutrients. Curr Pharm Des. 2014; 20(16):2760-5. Akiba Y, Kaunitz JD. PMID: 23886391.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    61. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Dig Dis Sci. 2014 Jun; 59(6):1286-95. Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 24379150.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    62. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2013 Nov; 29(6):642-9. Kemmerly T, Kaunitz JD. PMID: 24100725.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    63. Bringing the Bacon home. Dig Dis Sci. 2013 Nov; 58(11):3070-1. Kaunitz JD. PMID: 24122621.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity. Dig Dis Sci. 2013 Oct; 58(10):2756-66. Soldavini J, Kaunitz JD. PMID: 23839339.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    65. Introduction to the "paradigm shifts in perspective" series. Dig Dis Sci. 2013 Jul; 58(7):1825-6. Kaunitz JD. PMID: 23756736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    66. Wireless telemetry and cystic fibrosis: just the pHacts. Dig Dis Sci. 2013 Aug; 58(8):2129-30. Kaunitz JD, Akiba Y. PMID: 23748712.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    67. Introduction to the "GRG Scholars Invited Reviews". Dig Dis Sci. 2013 May; 58(5):1175. Souza RF, Kaunitz JD. PMID: 23579293.
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    68. Covering digestive diseases and sciences: how to judge a journal by its cover. Dig Dis Sci. 2013 Mar; 58(3):592-5. Palileo BM, Kaunitz JD. PMID: 23504332.
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    69. May the truth be with you: lubiprostone as EP receptor agonist/ClC-2 internalizing "inhibitor". Dig Dis Sci. 2012 Nov; 57(11):2740-2. Akiba Y, Kaunitz JD. PMID: 23001408.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    70. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2012 Nov; 28(6):594-601. Al-Jiboury H, Kaunitz JD. PMID: 22954689.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    71. From bedside to bench: reverse engineering medical progress. Dig Dis Sci. 2012 Oct; 57(10):2481-3. Kaunitz JD. PMID: 22983560.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid-induced bicarbonate secretion in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2012 Oct; 303(7):G810-6. Inoue T, Wang JH, Higashiyama M, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 22821947.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    73. Gastrointestinal defense mechanisms. Curr Opin Gastroenterol. 2011 Oct; 27(6):543-8. Palileo C, Kaunitz JD. PMID: 21897225.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    74. Umami receptor activation increases duodenal bicarbonate secretion via glucagon-like peptide-2 release in rats. J Pharmacol Exp Ther. 2011 Nov; 339(2):464-73. Wang JH, Inoue T, Higashiyama M, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 21846840.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    75. Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease. Eur J Clin Invest. 2012 Feb; 42(2):195-202. Hershcovici T, Poh CH, Fass OZ, Ashpole N, Akiba Y, Guillén-Rodríguez JM, Kaunitz JD, Fass R. PMID: 21679182.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    76. Duodenal chemosensing and mucosal defenses. Digestion. 2011; 83 Suppl 1:25-31. Akiba Y, Kaunitz JD. PMID: 21389725.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    77. Purinergic regulation of duodenal surface pH and ATP concentration: implications for mucosal defence, lipid uptake and cystic fibrosis. Acta Physiol (Oxf). 2011 Jan; 201(1):109-16. Kaunitz JD, Akiba Y. PMID: 20560899.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    78. Duodenal chemosensing: master control for epigastric sensation? J Gastroenterol Hepatol. 2011 Jan; 26(1):6-7. Akiba Y, Kaunitz JD. PMID: 21073675.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    79. Mechanisms of intragastric pH sensing. Curr Gastroenterol Rep. 2010 Dec; 12(6):465-70. Goo T, Akiba Y, Kaunitz JD. PMID: 20938760.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    80. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2010 Nov; 26(6):604-10. deFoneska A, Kaunitz JD. PMID: 20948371.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    81. Lafutidine, a protective H2 receptor antagonist, enhances mucosal defense in rat esophagus. Dig Dis Sci. 2010 Nov; 55(11):3063-9. Akiba Y, Kaunitz JD. PMID: 20824506.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    82. Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in rats. J Pharmacol Exp Ther. 2010 Dec; 335(3):607-13. Ham M, Mizumori M, Watanabe C, Wang JH, Inoue T, Nakano T, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 20805305.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    83. Unusual complication: superior mesenteric artery syndrome and closed loop gastroduodenal obstruction after adjustable gastric banding. Surg Obes Relat Dis. 2011 Mar-Apr; 7(2):237-9. Bergmann LL, Zimmerman P, Kaunitz JD. PMID: 21130049.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    84. Evaluation and treatment of iron deficiency anemia: a gastroenterological perspective. Dig Dis Sci. 2010 Mar; 55(3):548-59. Zhu A, Kaneshiro M, Kaunitz JD. PMID: 20108038.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    85. Gut sensing mechanisms. Curr Gastroenterol Rep. 2009 Dec; 11(6):442-7. deFonseka A, Kaunitz J. PMID: 19903419.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    86. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2009 Nov; 25(6):537-43. Nayeb-Hashemi H, Kaunitz JD. PMID: 19654540.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    87. Lubiprostone stimulates duodenal bicarbonate secretion in rats. Dig Dis Sci. 2009 Oct; 54(10):2063-9. Mizumori M, Akiba Y, Kaunitz JD. PMID: 19657734.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    88. Luminal L-glutamate enhances duodenal mucosal defense mechanisms via multiple glutamate receptors in rats. Am J Physiol Gastrointest Liver Physiol. 2009 Oct; 297(4):G781-91. Akiba Y, Watanabe C, Mizumori M, Kaunitz JD. PMID: 19643955.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    89. Luminal chemosensing and upper gastrointestinal mucosal defenses. Am J Clin Nutr. 2009 Sep; 90(3):826S-831S. Akiba Y, Kaunitz JD. PMID: 19571224.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    90. Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum. J Physiol. 2009 Jul 15; 587(Pt 14):3651-63. Mizumori M, Ham M, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 19451200.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    91. Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration. Am J Physiol Gastrointest Liver Physiol. 2009 Jul; 297(1):G207-14. Nakano T, Inoue I, Alpers DH, Akiba Y, Katayama S, Shinozaki R, Kaunitz JD, Ohshima S, Akita M, Takahashi S, Koyama I, Matsushita M, Komoda T. PMID: 19407215.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    92. Gastroduodenal mucosal defense. Curr Gastroenterol Rep. 2008 Dec; 10(6):548-54. Zhu A, Kaunitz J. PMID: 19006609.
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    93. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2008 Nov; 24(6):665-73. Ham M, Kaunitz JD. PMID: 19122513.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    94. TNAP, TrAP, ecto-purinergic signaling, and bone remodeling. J Cell Biochem. 2008 Oct 15; 105(3):655-62. Kaunitz JD, Yamaguchi DT. PMID: 18773425.
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    95. CFTR inhibition augments NHE3 activity during luminal high CO2 exposure in rat duodenal mucosa. Am J Physiol Gastrointest Liver Physiol. 2008 Jun; 294(6):G1318-27. Mizumori M, Choi Y, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 18420826.
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    96. Personal reminiscences about Morton Grossman and the founding of the Center for Ulcer Research and Education (CURE). Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1109-13. Guth PH, Kaunitz JD. PMID: 18356532.
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    97. Gastroduodenal defense. Curr Opin Gastroenterol. 2007 Nov; 23(6):607-16. Ham M, Kaunitz JD. PMID: 17906436.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    98. Duodenal brush border intestinal alkaline phosphatase activity affects bicarbonate secretion in rats. Am J Physiol Gastrointest Liver Physiol. 2007 Dec; 293(6):G1223-33. Akiba Y, Mizumori M, Guth PH, Engel E, Kaunitz JD. PMID: 17916646.
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    99. Fistuloclysis: case report and literature review. Nutr Clin Pract. 2007 Oct; 22(5):553-7. Ham M, Horton K, Kaunitz J. PMID: 17906279.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    100. Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology. 2007 Nov; 133(5):1592-602. Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH. PMID: 17916355.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    101. NKCC1: tales from the dark side of the crypt. J Physiol. 2007 Jul 15; 582(Pt 2):477. Kaunitz JD. PMID: 17525110.
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    102. Evaluation of a pharmacist-managed hepatitis C care clinic. Am J Health Syst Pharm. 2007 Mar 15; 64(6):632-6. Smith JP, Dong MH, Kaunitz JD. PMID: 17353572.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    103. Review article: duodenal bicarbonate - mucosal protection, luminal chemosensing and acid-base balance. Aliment Pharmacol Ther. 2006 Dec; 24 Suppl 4:169-76. Kaunitz JD, Akiba Y. PMID: 17209861.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    104. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2006 Nov; 22(6):599-606. Dong MH, Kaunitz JD. PMID: 17053436.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    105. Duodenal carbonic anhydrase: mucosal protection, luminal chemosensing, and gastric acid disposal. Keio J Med. 2006 Sep; 55(3):96-106. Kaunitz JD, Akiba Y. PMID: 17008801.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    106. Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum. Gastroenterology. 2006 Jul; 131(1):142-52. Akiba Y, Ghayouri S, Takeuchi T, Mizumori M, Guth PH, Engel E, Swenson ER, Kaunitz JD. PMID: 16831598.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    107. Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa. J Physiol. 2006 Jun 15; 573(Pt 3):827-42. Mizumori M, Meyerowitz J, Takeuchi T, Lim S, Lee P, Supuran CT, Guth PH, Engel E, Kaunitz JD, Akiba Y. PMID: 16556652.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    108. A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 289(4):G753-9. Akiba Y, Jung M, Ouk S, Kaunitz JD. PMID: 15905414.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    109. Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats. Peptides. 2005 Sep; 26(9):1580-9. Kawakubo K, Akiba Y, Adelson D, Guth PH, Engel E, Taché Y, Kaunitz JD. PMID: 16112396.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    110. Gastroduodenal mucosal defense: role of endogenous mediators. Curr Opin Gastroenterol. 2004 Nov; 20(6):526-32. Kaunitz JD, Akiba Y. PMID: 15703677.
      View in: PubMed   Mentions: 4     Fields:    
    111. Mechanism of augmented duodenal HCO(3)(-) secretion after elevation of luminal CO(2). Am J Physiol Gastrointest Liver Physiol. 2005 Mar; 288(3):G557-63. Furukawa O, Hirokawa M, Zhang L, Takeuchi T, Bi LC, Guth PH, Engel E, Akiba Y, Kaunitz JD. PMID: 15499081.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    112. Cystic fibrosis gene mutation reduces epithelial cell acidification and injury in acid-perfused mouse duodenum. Gastroenterology. 2004 Oct; 127(4):1162-73. Hirokawa M, Takeuchi T, Chu S, Akiba Y, Wu V, Guth PH, Engel E, Montrose MH, Kaunitz JD. PMID: 15480994.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    113. Low-dose PGE2 mimics the duodenal secretory response to luminal acid in mice. Am J Physiol Gastrointest Liver Physiol. 2004 Jun; 286(6):G891-8. Hirokawa M, Furukawa O, Guth PH, Engel E, Kaunitz JD. PMID: 14764447.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    114. Acid-sensing protective mechanisms of duodenum. J Physiol Pharmacol. 2003 Dec; 54 Suppl 4:19-26. Kaunitz JD, Akiba Y. PMID: 15075446.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    115. Gastroduodenal mucosal defense: an integrated protective response. Curr Opin Gastroenterol. 2003 Nov; 19(6):526-32. Bi LC, Kaunitz JD. PMID: 15703600.
      View in: PubMed   Mentions: 3     Fields:    
    116. NHE3 inhibition activates duodenal bicarbonate secretion in the rat. Am J Physiol Gastrointest Liver Physiol. 2004 Jan; 286(1):G102-9. Furukawa O, Bi LC, Guth PH, Engel E, Hirokawa M, Kaunitz JD. PMID: 12881227.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    117. Role of protein kinases on acid-induced duodenal bicarbonate secretion in rats. Pharmacology. 2003 Feb; 67(2):99-105. Furukawa O, Hirokawa M, Guth PH, Engel E, Kaunitz JD. PMID: 12566854.
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    118. Acid-sensing pathways in rat gastrointestinal mucosa. J Gastroenterol. 2002 Nov; 37 Suppl 14:133-8. Akiba Y, Nakamura M, Nagata H, Kaunitz JD, Ishii H. PMID: 12572881.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    119. Gastroduodenal mucosal defense: an integrated protective response. Curr Opin Gastroenterol. 2002 Nov; 18(6):650-7. Guha S, Kaunitz JD. PMID: 17033343.
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    120. Luminal acid elicits a protective duodenal mucosal response. Keio J Med. 2002 Mar; 51(1):29-35. Kaunitz JD, Akiba Y. PMID: 11951376.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    121. Integrated duodenal protective response to acid. Life Sci. 2001 Nov 09; 69(25-26):3073-81. Kaunitz JD, Akiba Y. PMID: 11758832.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    122. Duodenal intracellular bicarbonate and the 'CF paradox'. JOP. 2001 Jul; 2(4 Suppl):268-73. Kaunitz JD, Akiba Y. PMID: 11875270.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    123. Barrier function of gastric mucus. Keio J Med. 1999 Jun; 48(2):63-8. Kaunitz JD. PMID: 10405521.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
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