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Altshuler Lori

Title(s)Professor, Psychiatry and Biobehavioral Sciences
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    Other Positions
    Title(s)Research Director, Resnick Neuropsychiatric Hospital

    Title(s)Chief, Mental Health Clinic

    Title(s)Chief, Bipolar Disorder Clinic


    Collapse Research 
    Collapse Research Activities and Funding
    Tractography, White Matter Integrity and fMRI In Bipolar Disorder
    NIH/NIMH R21MH086104May 1, 2009 - Apr 30, 2012
    Role: Principal Investigator
    Mapping Brain Structure to Function in Euthymic Subjects with Bipolar Disorder
    NIH/NIMH R01MH084955Jan 1, 2009 - Mar 31, 2014
    Role: Principal Investigator
    Bipolar II Depression: Lithium, SSRI or the Combination
    NIH/NIMH R01MH074707Jul 1, 2006 - Jun 30, 2013
    Role: Principal Investigator
    Mapping Brain Structure to Function in Bipolar Disorder
    NIH/NIMH R21MH075944Jul 1, 2006 - Jun 30, 2009
    Role: Principal Investigator
    Risk and Predictors of Postpartum Depression
    NIH/NIMH R01MH063844Apr 11, 2003 - Mar 31, 2009
    Role: Principal Investigator
    FMRI in Bipolar Illness
    NIH/NIMH K24MH001848Jan 1, 2000 - Dec 31, 2012
    Role: Principal Investigator
    DETERMINANTS OF FUNCTIONAL RECOVERY IN BIPOLAR ILLNESS
    NIH/NIMH R01MH057762Jan 1, 2000 - Dec 31, 2005
    Role: Principal Investigator
    RELAPSE AND PREDICTORS OF DEPRESSION IN PREGNANCY
    NIH/NIMH R01MH056492Dec 1, 1998 - Nov 30, 2003
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee J, Reavis EA, Engel SA, Altshuler LL, Cohen MS, Glahn DC, Nuechterlein KH, Wynn JK, Green MF. fMRI evidence of aberrant neural adaptation for objects in schizophrenia and bipolar disorder. Hum Brain Mapp. 2019 Apr 01; 40(5):1608-1617. PMID: 30575206.
      View in: PubMed
    2. van der Markt A, Klumpers UM, Draisma S, Dols A, Nolen WA, Post RM, Altshuler LL, Frye MA, Grunze H, Keck PE, McElroy SL, Suppes T, Beekman AT, Kupka RW. Testing a clinical staging model for bipolar disorder using longitudinal life chart data. Bipolar Disord. 2019 05; 21(3):228-234. PMID: 30447123.
      View in: PubMed
    3. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Nolen WA. More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring. Eur Arch Psychiatry Clin Neurosci. 2018 Aug 11. PMID: 30099616.
      View in: PubMed
    4. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. Multigenerational transmission of liability to psychiatric illness in offspring of parents with bipolar disorder. Bipolar Disord. 2018 Jun 21. PMID: 29926532.
      View in: PubMed
    5. Post RM, Leverich GS, McElroy S, Kupka R, Suppes T, Altshuler L, Nolen W, Frye M, Keck P, Grunze H, Hellemann G. Prevalence of axis II comorbidities in bipolar disorder: relationship to mood state. Bipolar Disord. 2018 06; 20(4):303-312. PMID: 29369448.
      View in: PubMed
    6. Riemann G, Weisscher N, Post RM, Altshuler L, McElroy S, Frye MA, Keck PE, Leverich GS, Suppes T, Grunze H, Nolen WA, Kupka RW. The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder. Int J Bipolar Disord. 2017 Sep 25; 5(1):31. PMID: 28944443.
      View in: PubMed
    7. Suri R, Stowe ZN, Cohen LS, Newport DJ, Burt VK, Aquino-Elias AR, Knight BT, Mintz J, Altshuler LL. Prospective Longitudinal Study of Predictors of Postpartum-Onset Depression in Women With a History of Major Depressive Disorder. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1110-1116. PMID: 28297589.
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    8. Reavis EA, Lee J, Wynn JK, Engel SA, Cohen MS, Nuechterlein KH, Glahn DC, Altshuler LL, Green MF. Assessing neural tuning for object perception in schizophrenia and bipolar disorder with multivariate pattern analysis of fMRI data. Neuroimage Clin. 2017; 16:491-497. PMID: 28932681.
      View in: PubMed
    9. Tishler TA, Bartzokis G, Lu PH, Raven EP, Khanoyan M, Kirkpatrick CJ, Pyle MH, Villablanca JP, Altshuler LL, Mintz J, Ventura J, Casaus LR, Subotnik KL, Nuechterlein KH, Ellingson BM. Abnormal Trajectory of Intracortical Myelination in Schizophrenia Implicates White Matter in Disease Pathophysiology and the Therapeutic Mechanism of Action of Antipsychotics. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 05; 3(5):454-462. PMID: 29735155.
      View in: PubMed
    10. Altshuler LL, Sugar CA, McElroy SL, Calimlim B, Gitlin M, Keck PE, Aquino-Elias A, Martens BE, Fischer EG, English TL, Roach J, Suppes T. Switch Rates During Acute Treatment for Bipolar II Depression With Lithium, Sertraline, or the Two Combined: A Randomized Double-Blind Comparison. Am J Psychiatry. 2017 Mar 01; 174(3):266-276. PMID: 28135846.
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    11. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. More childhood onset bipolar disorder in the United States than Canada or Europe: Implications for treatment and prevention. Neurosci Biobehav Rev. 2017 Mar; 74(Pt A):204-213. PMID: 28119069.
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    12. Lee J, Rizzo S, Altshuler L, Glahn DC, Miklowitz DJ, Sugar CA, Wynn JK, Green MF. Deconstructing Bipolar Disorder and Schizophrenia: A cross-diagnostic cluster analysis of cognitive phenotypes. J Affect Disord. 2017 Feb; 209:71-79. PMID: 27888723.
      View in: PubMed
    13. Joshi SH, Vizueta N, Foland-Ross L, Townsend JD, Bookheimer SY, Thompson PM, Narr KL, Altshuler LL. Relationships Between Altered Functional Magnetic Resonance Imaging Activation and Cortical Thickness in Patients With Euthymic Bipolar I Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Nov; 1(6):507-517. PMID: 27990494.
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    14. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Nolen WA. Illnesses in siblings of US patients with bipolar disorder relate to multigenerational family history and patients severity of illness. J Affect Disord. 2017 Jan 01; 207:313-319. PMID: 27741468.
      View in: PubMed
    15. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. Age at Onset of Bipolar Disorder Related to Parental and Grandparental Illness Burden. J Clin Psychiatry. 2016 Oct; 77(10):e1309-e1315. PMID: 27631141.
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    16. Post RM, Kupka R, Keck PE, McElroy SL, Altshuler LL, Frye MA, Rowe M, Grunze H, Suppes T, Leverich GS, Nolen WA. Further Evidence of a Cohort Effect in Bipolar Disorder: More Early Onsets and Family History of Psychiatric Illness in More Recent Epochs. J Clin Psychiatry. 2016 08; 77(8):1043-9. PMID: 27379705.
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    17. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. Age of onset of bipolar disorder: Combined effect of childhood adversity and familial loading of psychiatric disorders. J Psychiatr Res. 2016 10; 81:63-70. PMID: 27392070.
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    18. Miller S, Suppes T, Mintz J, Hellemann G, Frye MA, McElroy SL, Nolen WA, Kupka R, Leverich GS, Grunze H, Altshuler LL, Keck PE, Post RM. Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network. Am J Psychiatry. 2016 Oct 01; 173(10):1015-1023. PMID: 27079133.
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    19. Horan WP, Wynn JK, Hajcak G, Altshuler L, Green MF. Distinct patterns of dysfunctional appetitive and aversive motivation in bipolar disorder versus schizophrenia: An event-related potential study. J Abnorm Psychol. 2016 05; 125(4):576-87. PMID: 26845261.
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    20. Post RM, Leverich GS, Kupka R, Keck PE, McElroy SL, Altshuler LL, Frye MA, Rowe M, Grunze H, Suppes T, Nolen WA. Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder. Compr Psychiatry. 2016 Apr; 66:146-56. PMID: 26995248.
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    21. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. More illness in offspring of bipolar patients from the U.S. compared to Europe. J Affect Disord. 2016 Feb; 191:180-6. PMID: 26655863.
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    22. Post RM, Leverich GS, Kupka R, Keck PE, McElroy SL, Altshuler LL, Frye MA, Rowe M, Grunze H, Suppes T, Nolen WA. Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany. Psychiatr Genet. 2015 Oct; 25(5):194-200. PMID: 26146875.
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    23. Post RM, Altshuler L, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder. J Neuropsychiatry Clin Neurosci. 2015; 27(4):304-10. PMID: 26258489.
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    24. Ajilore O, Vizueta N, Walshaw P, Zhan L, Leow A, Altshuler LL. Connectome signatures of neurocognitive abnormalities in euthymic bipolar I disorder. J Psychiatr Res. 2015 Sep; 68:37-44. PMID: 26228398.
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    25. Fears SC, Schür R, Sjouwerman R, Service SK, Araya C, Araya X, Bejarano J, Knowles E, Gomez-Makhinson J, Lopez MC, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Navarro L, Tishler TA, Altshuler L, Bartzokis G, Escobar JI, Glahn DC, Thompson PM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Cantor RM, Freimer NB, Bearden CE. Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder. Brain. 2015 Jul; 138(Pt 7):2087-102. PMID: 25943422.
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    26. Tabak NT, Green MF, Wynn JK, Proudfit GH, Altshuler L, Horan WP. Perceived emotional intelligence is impaired and associated with poor community functioning in schizophrenia and bipolar disorder. Schizophr Res. 2015 Mar; 162(1-3):189-95. PMID: 25579055.
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    27. Post RM, Altshuler LL, Leverich GS, Nolen WA, Kupka R, Grunze H, Frye MA, Suppes T, McElroy SL, Keck PE, Rowe M. Illness progression as a function of independent and accumulating poor prognosis factors in outpatients with bipolar disorder in the United States. Prim Care Companion CNS Disord. 2014; 16(6). PMID: 25834764.
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    28. Penfold C, Vizueta N, Townsend JD, Bookheimer SY, Altshuler LL. Frontal lobe hypoactivation in medication-free adults with bipolar II depression during response inhibition. Psychiatry Res. 2015 Mar 30; 231(3):202-9. PMID: 25555505.
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    29. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Leverich GS, Grunze H, Suppes T, Keck PE, Nolen WA. Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder. Bipolar Disord. 2015 May; 17(3):323-30. PMID: 25307301.
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    30. Suri R, Lin AS, Cohen LS, Altshuler LL. Acute and long-term behavioral outcome of infants and children exposed in utero to either maternal depression or antidepressants: a review of the literature. J Clin Psychiatry. 2014 Oct; 75(10):e1142-52. PMID: 25373125.
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    31. Corp SA, Gitlin MJ, Altshuler LL. A review of the use of stimulants and stimulant alternatives in treating bipolar depression and major depressive disorder. J Clin Psychiatry. 2014 Sep; 75(9):1010-8. PMID: 25295426.
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    32. Post RM, Altshuler L, Leverich GS, Frye MA, Suppes T, McElroy SL, Keck PE, Nolen WA, Kupka RW, Grunze H, Rowe M. Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with bipolar disorder. Compr Psychiatry. 2015 Jan; 56:21-8. PMID: 25284280.
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    33. Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Franco J, Lopez MC, Montoya G, Montoya P, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Ericson M, Jalbrzikowski M, Luykx JJ, Navarro L, Tishler TA, Altshuler L, Bartzokis G, Escobar J, Glahn DC, Ospina-Duque J, Risch N, Ruiz-Linares A, Thompson PM, Cantor RM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Freimer NB, Bearden CE. Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry. 2014 Apr; 71(4):375-87. PMID: 24522887.
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    34. Post RM, Altshuler LL, Leverich GS, Frye MA, Suppes T, McElroy SL, Keck PE, Nolen WA, Kupka RW, Grunze H, Rowe M. More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany. J Nerv Ment Dis. 2014 Apr; 202(4):265-70. PMID: 24647213.
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    35. Congdon E, Altshuler LL, Mumford JA, Karlsgodt KH, Sabb FW, Ventura J, McGough JJ, London ED, Cannon TD, Bilder RM, Poldrack RA. Neural activation during response inhibition in adult attention-deficit/hyperactivity disorder: preliminary findings on the effects of medication and symptom severity. Psychiatry Res. 2014 Apr 30; 222(1-2):17-28. PMID: 24581734.
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    36. Jahshan C, Wynn JK, McCleery A, Glahn DC, Altshuler LL, Green MF. Cross-diagnostic comparison of visual processing in bipolar disorder and schizophrenia. J Psychiatr Res. 2014 Apr; 51:42-8. PMID: 24433849.
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    37. Pacchiarotti I, Bond DJ, Baldessarini RJ, Nolen WA, Grunze H, Licht RW, Post RM, Berk M, Goodwin GM, Sachs GS, Tondo L, Findling RL, Youngstrom EA, Tohen M, Undurraga J, González-Pinto A, Goldberg JF, Yildiz A, Altshuler LL, Calabrese JR, Mitchell PB, Thase ME, Koukopoulos A, Colom F, Frye MA, Malhi GS, Fountoulakis KN, Vázquez G, Perlis RH, Ketter TA, Cassidy F, Akiskal H, Azorin JM, Valentí M, Mazzei DH, Lafer B, Kato T, Mazzarini L, Martínez-Aran A, Parker G, Souery D, Ozerdem A, McElroy SL, Girardi P, Bauer M, Yatham LN, Zarate CA, Nierenberg AA, Birmaher B, Kanba S, El-Mallakh RS, Serretti A, Rihmer Z, Young AH, Kotzalidis GD, MacQueen GM, Bowden CL, Ghaemi SN, Lopez-Jaramillo C, Rybakowski J, Ha K, Perugi G, Kasper S, Amsterdam JD, Hirschfeld RM, Kapczinski F, Vieta E. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013 Nov; 170(11):1249-62. PMID: 24030475.
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    38. Post RM, Altshuler L, Leverich G, Nolen W, Kupka R, Grunze H, Frye M, Suppes T, McElroy S, Keck P, Rowe M. More stressors prior to and during the course of bipolar illness in patients from the United States compared with the Netherlands and Germany. Psychiatry Res. 2013 Dec 30; 210(3):880-6. PMID: 24021999.
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    39. Reddy LF, Lee J, Davis MC, Altshuler L, Glahn DC, Miklowitz DJ, Green MF. Impulsivity and risk taking in bipolar disorder and schizophrenia. Neuropsychopharmacology. 2014 Jan; 39(2):456-63. PMID: 23963117.
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    40. Reid JG, Gitlin MJ, Altshuler LL. Lamotrigine in psychiatric disorders. J Clin Psychiatry. 2013 Jul; 74(7):675-84. PMID: 23945444.
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    41. Gadelkarim JJ, Ajilore O, Schonfeld D, Zhan L, Thompson PM, Feusner JD, Kumar A, Altshuler LL, Leow AD. Investigating brain community structure abnormalities in bipolar disorder using path length associated community estimation. Hum Brain Mapp. 2014 May; 35(5):2253-64. PMID: 23798337.
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    42. Torrisi SJ, Lieberman MD, Bookheimer SY, Altshuler LL. Advancing understanding of affect labeling with dynamic causal modeling. Neuroimage. 2013 Nov 15; 82:481-8. PMID: 23774393.
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    43. Torgerson CM, Irimia A, Leow AD, Bartzokis G, Moody TD, Jennings RG, Alger JR, Van Horn JD, Altshuler LL. DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects. Brain Imaging Behav. 2013 Jun; 7(2):129-39. PMID: 23070746.
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    44. Barysheva M, Jahanshad N, Foland-Ross L, Altshuler LL, Thompson PM. White matter microstructural abnormalities in bipolar disorder: A whole brain diffusion tensor imaging study. Neuroimage Clin. 2013; 2:558-68. PMID: 24179807.
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    45. Lee J, Altshuler L, Glahn DC, Miklowitz DJ, Ochsner K, Green MF. Social and nonsocial cognition in bipolar disorder and schizophrenia: relative levels of impairment. Am J Psychiatry. 2013 Mar; 170(3):334-41. PMID: 23450289.
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    46. Torrisi S, Moody TD, Vizueta N, Thomason ME, Monti MM, Townsend JD, Bookheimer SY, Altshuler LL. Differences in resting corticolimbic functional connectivity in bipolar I euthymia. Bipolar Disord. 2013 Mar; 15(2):156-66. PMID: 23347587.
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    47. Post RM, Altshuler LL, Leverich GS, Frye MA, Suppes T, McElroy SL, Keck PE, Nolen WA, Kupka RW, Grunze H, Rowe M. Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder. J Affect Disord. 2013 May; 147(1-3):288-94. PMID: 23337654.
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    48. Abulseoud OA, Gitlin M, Altshuler L, Frye MA. Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study. Brain Behav. 2013 Mar; 3(2):89-94. PMID: 23533025.
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    49. Kim WH, Adluru N, Chung MK, Charchut S, GadElkarim JJ, Altshuler L, Moody T, Kumar A, Singh V, Leow AD. Multi-resolutional brain network filtering and analysis via wavelets on non-Euclidean space. Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):643-51. PMID: 24505816.
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    50. Hegarty CE, Foland-Ross LC, Narr KL, Sugar CA, McGough JJ, Thompson PM, Altshuler LL. ADHD comorbidity can matter when assessing cortical thickness abnormalities in patients with bipolar disorder. Bipolar Disord. 2012 Dec; 14(8):843-55. PMID: 23167934.
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    51. Foland-Ross LC, Thompson PM, Sugar CA, Narr KL, Penfold C, Vasquez RE, Townsend J, Fischer J, Saharan P, Bearden CE, Altshuler LL. Three-dimensional mapping of hippocampal and amygdalar structure in euthymic adults with bipolar disorder not treated with lithium. Psychiatry Res. 2013 Mar 30; 211(3):195-201. PMID: 23149020.
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    52. Leow A, Ajilore O, Zhan L, Arienzo D, GadElkarim J, Zhang A, Moody T, Van Horn J, Feusner J, Kumar A, Thompson P, Altshuler L. Impaired inter-hemispheric integration in bipolar disorder revealed with brain network analyses. Biol Psychiatry. 2013 Jan 15; 73(2):183-93. PMID: 23122540.
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    53. Townsend JD, Sugar CA, Walshaw PD, Vasquez RE, Foland-Ross LC, Moody TD, Bookheimer SY, McGough JJ, Altshuler LL. Frontostriatal neuroimaging findings differ in patients with bipolar disorder who have or do not have ADHD comorbidity. J Affect Disord. 2013 May; 147(1-3):389-96. PMID: 23057969.
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    54. Bartzokis G, Lu PH, Heydari P, Couvrette A, Lee GJ, Kalashyan G, Freeman F, Grinstead JW, Villablanca P, Finn JP, Mintz J, Alger JR, Altshuler LL. Multimodal magnetic resonance imaging assessment of white matter aging trajectories over the lifespan of healthy individuals. Biol Psychiatry. 2012 Dec 15; 72(12):1026-34. PMID: 23017471.
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    55. Townsend JD, Torrisi SJ, Lieberman MD, Sugar CA, Bookheimer SY, Altshuler LL. Frontal-amygdala connectivity alterations during emotion downregulation in bipolar I disorder. Biol Psychiatry. 2013 Jan 15; 73(2):127-35. PMID: 22858151.
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    56. Vizueta N, Rudie JD, Townsend JD, Torrisi S, Moody TD, Bookheimer SY, Altshuler LL. Regional fMRI hypoactivation and altered functional connectivity during emotion processing in nonmedicated depressed patients with bipolar II disorder. Am J Psychiatry. 2012 Aug; 169(8):831-40. PMID: 22773540.
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    57. Strakowski SM, Adler CM, Almeida J, Altshuler LL, Blumberg HP, Chang KD, DelBello MP, Frangou S, McIntosh A, Phillips ML, Sussman JE, Townsend JD. The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar Disord. 2012 Jun; 14(4):313-25. PMID: 22631617.
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    58. Townsend J, Altshuler LL. Emotion processing and regulation in bipolar disorder: a review. Bipolar Disord. 2012 Jun; 14(4):326-39. PMID: 22631618.
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    59. Townsend JD, Bookheimer SY, Foland-Ross LC, Moody TD, Eisenberger NI, Fischer JS, Cohen MS, Sugar CA, Altshuler LL. Deficits in inferior frontal cortex activation in euthymic bipolar disorder patients during a response inhibition task. Bipolar Disord. 2012 Jun; 14(4):442-50. PMID: 22631623.
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    60. Hegarty CE, Foland-Ross LC, Narr KL, Townsend JD, Bookheimer SY, Thompson PM, Altshuler LL. Anterior cingulate activation relates to local cortical thickness. Neuroreport. 2012 May 09; 23(7):420-4. PMID: 22440976.
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    61. Jahshan C, Wynn JK, Mathis KI, Altshuler LL, Glahn DC, Green MF. Cross-diagnostic comparison of duration mismatch negativity and P3a in bipolar disorder and schizophrenia. Bipolar Disord. 2012 May; 14(3):239-48. PMID: 22548897.
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    62. Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL. Mood-state effects on amygdala volume in bipolar disorder. J Affect Disord. 2012 Aug; 139(3):298-301. PMID: 22521854.
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    63. Post RM, Leverich GS, Altshuler LL, Frye MA, Suppes T, McElroy SL, Keck PE, Nolen WA, Rowe M, Kupka RW, Grunze H, Goodwin FK. Relationship of prior antidepressant exposure to long-term prospective outcome in bipolar I disorder outpatients. J Clin Psychiatry. 2012 Jul; 73(7):924-30. PMID: 22480597.
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    64. Tishler TA, Raven EP, Lu PH, Altshuler LL, Bartzokis G. Premenopausal hysterectomy is associated with increased brain ferritin iron. Neurobiol Aging. 2012 Sep; 33(9):1950-8. PMID: 21925770.
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    65. Foland-Ross LC, Bookheimer SY, Lieberman MD, Sugar CA, Townsend JD, Fischer J, Torrisi S, Penfold C, Madsen SK, Thompson PM, Altshuler LL. Normal amygdala activation but deficient ventrolateral prefrontal activation in adults with bipolar disorder during euthymia. Neuroimage. 2012 Jan 02; 59(1):738-44. PMID: 21854858.
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    66. Bartzokis G, Lu PH, Amar CP, Raven EP, Detore NR, Altshuler LL, Mintz J, Ventura J, Casaus LR, Luo JS, Subotnik KL, Nuechterlein KH. Long acting injection versus oral risperidone in first-episode schizophrenia: differential impact on white matter myelination trajectory. Schizophr Res. 2011 Oct; 132(1):35-41. PMID: 21767934.
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    67. Bearden CE, Shih VH, Green MF, Gitlin M, Sokolski KN, Levander E, Marusak S, Hammen C, Sugar CA, Altshuler LL. The impact of neurocognitive impairment on occupational recovery of clinically stable patients with bipolar disorder: a prospective study. Bipolar Disord. 2011 Jun; 13(4):323-33. PMID: 21843272.
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    68. Suri R, Hellemann G, Stowe ZN, Cohen LS, Aquino A, Altshuler LL. A prospective, naturalistic, blinded study of early neurobehavioral outcomes for infants following prenatal antidepressant exposure. J Clin Psychiatry. 2011 Jul; 72(7):1002-7. PMID: 21672498.
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    69. Brooks JO, Foland-Ross LC, Thompson PM, Altshuler LL. Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression. Psychiatry Res. 2011 Jul 30; 193(1):53-5. PMID: 21561743.
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    70. Bartzokis G, Lu PH, Tingus K, Peters DG, Amar CP, Tishler TA, Finn JP, Villablanca P, Altshuler LL, Mintz J, Neely E, Connor JR. Gender and iron genes may modify associations between brain iron and memory in healthy aging. Neuropsychopharmacology. 2011 Jun; 36(7):1375-84. PMID: 21389980.
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    71. Post RM, Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Nolen WA, Kupka R, Grunze H, Walden J, Rowe M. Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany. Int Clin Psychopharmacol. 2011 Mar; 26(2):96-106. PMID: 21178634.
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    72. Yan-Meier L, Eberhart NK, Hammen CL, Gitlin M, Sokolski K, Altshuler L. Stressful life events predict delayed functional recovery following treatment for mania in bipolar disorder. Psychiatry Res. 2011 Apr 30; 186(2-3):267-71. PMID: 20888051.
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    73. Foland-Ross LC, Thompson PM, Sugar CA, Madsen SK, Shen JK, Penfold C, Ahlf K, Rasser PE, Fischer J, Yang Y, Townsend J, Bookheimer SY, Altshuler LL. Investigation of cortical thickness abnormalities in lithium-free adults with bipolar I disorder using cortical pattern matching. Am J Psychiatry. 2011 May; 168(5):530-9. PMID: 21285139.
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    74. Foland-Ross LC, Altshuler LL, Bookheimer SY, Lieberman MD, Townsend J, Penfold C, Moody T, Ahlf K, Shen JK, Madsen SK, Rasser PE, Toga AW, Thompson PM. Amygdala reactivity in healthy adults is correlated with prefrontal cortical thickness. J Neurosci. 2010 Dec 08; 30(49):16673-8. PMID: 21148006.
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    86. Binder EB, Newport DJ, Zach EB, Smith AK, Deveau TC, Altshuler LL, Cohen LS, Stowe ZN, Cubells JF. A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort. J Psychiatr Res. 2010 Jul; 44(10):640-6. PMID: 20045118.
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    87. Hamilton LS, Altshuler LL, Townsend J, Bookheimer SY, Phillips OR, Fischer J, Woods RP, Mazziotta JC, Toga AW, Nuechterlein KH, Narr KL. Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task. Hum Brain Mapp. 2009 Dec; 30(12):3958-69. PMID: 19449330.
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    88. Schreibman Cohen A, Daley M, Siddarth P, Levitt J, Loesch IK, Altshuler L, Ly R, Shields WD, Gurbani S, Caplan R. Amygdala volumes in childhood absence epilepsy. Epilepsy Behav. 2009 Nov; 16(3):436-41. PMID: 19766541.
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    89. Suri R, Altshuler LL. No decision is without risk. J Clin Psychiatry. 2009 Sep; 70(9):1319-20. PMID: 19818253.
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    90. Bartzokis G, Lu PH, Stewart SB, Oluwadara B, Lucas AJ, Pantages J, Pratt E, Sherin JE, Altshuler LL, Mintz J, Gitlin MJ, Subotnik KL, Nuechterlein KH. In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia. Schizophr Res. 2009 Sep; 113(2-3):322-31. PMID: 19616412.
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    91. Altshuler LL, Post RM, Hellemann G, Leverich GS, Nolen WA, Frye MA, Keck PE, Kupka RW, Grunze H, McElroy SL, Sugar CA, Suppes T. Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. J Clin Psychiatry. 2009 Apr; 70(4):450-7. PMID: 19358785.
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    95. Suri R, Hellemann G, Cohen L, Aquino A, Altshuler L. Saliva estriol levels in women with and without prenatal antidepressant treatment. Biol Psychiatry. 2008 Sep 15; 64(6):533-7. PMID: 18495086.
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    96. Shivakumar G, Bernstein IH, Suppes T, Keck PE, McElroy SL, Altshuler LL, Frye MA, Nolen WA, Kupka RW, Grunze H, Leverich GS, Mintz J, Post RM. Are bipolar mood symptoms affected by the phase of the menstrual cycle? J Womens Health (Larchmt). 2008 Apr; 17(3):473-8. PMID: 18328012.
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    97. Post RM, Luckenbaugh DA, Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Nolen WA, Kupka R, Grunze H, Walden J. Incidence of childhood-onset bipolar illness in the USA and Europe. Br J Psychiatry. 2008 Feb; 192(2):150-1. PMID: 18245035.
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    98. Foland LC, Altshuler LL, Sugar CA, Lee AD, Leow AD, Townsend J, Narr KL, Asuncion DM, Toga AW, Thompson PM. Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium. Neuroreport. 2008 Jan 22; 19(2):221-4. PMID: 18185112.
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    99. Foland LC, Altshuler LL, Bookheimer SY, Eisenberger N, Townsend J, Thompson PM. Evidence for deficient modulation of amygdala response by prefrontal cortex in bipolar mania. Psychiatry Res. 2008 Jan 15; 162(1):27-37. PMID: 18063349.
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    107. McElroy SL, Frye MA, Altshuler LL, Suppes T, Hellemann G, Black D, Mintz J, Kupka R, Nolen W, Leverich GS, Denicoff KD, Post RM, Keck PE. A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. Bipolar Disord. 2007 Jun; 9(4):426-34. PMID: 17547588.
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    138. Bauer MS, Altshuler L, Evans DR, Beresford T, Williford WO, Hauger R. Prevalence and distinct correlates of anxiety, substance, and combined comorbidity in a multi-site public sector sample with bipolar disorder. J Affect Disord. 2005 Apr; 85(3):301-15. PMID: 15780700.
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    148. Quanbeck CD, Stone DC, Scott CL, McDermott BE, Altshuler LL, Frye MA. Clinical and legal correlates of inmates with bipolar disorder at time of criminal arrest. J Clin Psychiatry. 2004 Feb; 65(2):198-203. PMID: 15003073.
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    149. Frye MA, Gitlin MJ, Altshuler LL. Unmet needs in bipolar depression. Depress Anxiety. 2004; 19(4):199-208. PMID: 15274168.
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    157. Hendrick V, Stowe ZN, Altshuler LL, Hwang S, Lee E, Haynes D. Placental passage of antidepressant medications. Am J Psychiatry. 2003 May; 160(5):993-6. PMID: 12727706.
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    158. Rasgon NL, Rao RC, Hwang S, Altshuler LL, Elman S, Zuckerbrow-Miller J, Korenman SG. Depression in women with polycystic ovary syndrome: clinical and biochemical correlates. J Affect Disord. 2003 May; 74(3):299-304. PMID: 12738050.
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    159. Frye MA, Altshuler LL, McElroy SL, Suppes T, Keck PE, Denicoff K, Nolen WA, Kupka R, Leverich GS, Pollio C, Grunze H, Walden J, Post RM. Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder. Am J Psychiatry. 2003 May; 160(5):883-9. PMID: 12727691.
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    160. Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Denicoff KD, Obrocea G, Nolen WA, Kupka R, Walden J, Grunze H, Perez S, Luckenbaugh DA, Post RM. Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. J Clin Psychiatry. 2003 May; 64(5):506-15. PMID: 12755652.
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    161. Altshuler LL, Frye MA, Gitlin MJ. Acceleration and augmentation strategies for treating bipolar depression. Biol Psychiatry. 2003 Apr 15; 53(8):691-700. PMID: 12706955.
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    162. Hendrick V, Smith LM, Hwang S, Altshuler LL, Haynes D. Weight gain in breastfed infants of mothers taking antidepressant medications. J Clin Psychiatry. 2003 Apr; 64(4):410-2. PMID: 12716242.
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    163. Frye MA, Gitlin MJ, Altshuler LL. Treating acute mania. J Fam Pract. 2003 Mar; Suppl:S10-3. PMID: 12676078.
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    164. Hendrick V, Smith LM, Suri R, Hwang S, Haynes D, Altshuler L. Birth outcomes after prenatal exposure to antidepressant medication. Am J Obstet Gynecol. 2003 Mar; 188(3):812-5. PMID: 12634662.
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    165. Bartzokis G, Altshuler L. Biological underpinnings of treatment resistance in schizophrenia: an hypothesis. Psychopharmacol Bull. 2003; 37(4):5-7. PMID: 15272475.
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    166. Altshuler L, Mintz J, Leight K. The Life Functioning Questionnaire (LFQ): a brief, gender-neutral scale assessing functional outcome. Psychiatry Res. 2002 Oct 10; 112(2):161-82. PMID: 12429362.
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    167. Suppes T, Chisholm KA, Dhavale D, Frye MA, Altshuler LL, McElroy SL, Keck PE, Nolen WA, Kupka R, Denicoff KD, Leverich GS, Rush AJ, Post RM. Tiagabine in treatment refractory bipolar disorder: a clinical case series. Bipolar Disord. 2002 Oct; 4(5):283-9. PMID: 12479659.
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    168. Hendrick V, Altshuler L. Management of major depression during pregnancy. Am J Psychiatry. 2002 Oct; 159(10):1667-73. PMID: 12359670.
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    169. Suri R, Stowe ZN, Hendrick V, Hostetter A, Widawski M, Altshuler LL. Estimates of nursing infant daily dose of fluoxetine through breast milk. Biol Psychiatry. 2002 Sep 01; 52(5):446-51. PMID: 12242061.
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    170. Altshuler LL, Gitlin MJ, Mintz J, Leight KL, Frye MA. Subsyndromal depression is associated with functional impairment in patients with bipolar disorder. J Clin Psychiatry. 2002 Sep; 63(9):807-11. PMID: 12363122.
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    171. Kay JH, Altshuler LL, Ventura J, Mintz J. Impact of axis II comorbidity on the course of bipolar illness in men: a retrospective chart review. Bipolar Disord. 2002 Aug; 4(4):237-42. PMID: 12190712.
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    172. Tohen M, Baker RW, Altshuler LL, Zarate CA, Suppes T, Ketter TA, Milton DR, Risser R, Gilmore JA, Breier A, Tollefson GA. Olanzapine versus divalproex in the treatment of acute mania. Am J Psychiatry. 2002 Jun; 159(6):1011-7. PMID: 12042191.
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    173. State RC, Altshuler LL, Frye MA. Mania and attention deficit hyperactivity disorder in a prepubertal child: diagnostic and treatment challenges. Am J Psychiatry. 2002 Jun; 159(6):918-25. PMID: 12042177.
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    174. Gitlin MJ, Suri R, Altshuler L, Zuckerbrow-Miller J, Fairbanks L. Bupropion-sustained release as a treatment for SSRI-induced sexual side effects. J Sex Marital Ther. 2002 Mar-Apr; 28(2):131-8. PMID: 11894796.
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    175. McElroy SL, Frye MA, Suppes T, Dhavale D, Keck PE, Leverich GS, Altshuler L, Denicoff KD, Nolen WA, Kupka R, Grunze H, Walden J, Post RM. Correlates of overweight and obesity in 644 patients with bipolar disorder. J Clin Psychiatry. 2002 Mar; 63(3):207-13. PMID: 11926719.
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    176. Kupka RW, Nolen WA, Post RM, McElroy SL, Altshuler LL, Denicoff KD, Frye MA, Keck PE, Leverich GS, Rush AJ, Suppes T, Pollio C, Drexhage HA. High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure. Biol Psychiatry. 2002 Feb 15; 51(4):305-11. PMID: 11958781.
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    177. Leverich GS, McElroy SL, Suppes T, Keck PE, Denicoff KD, Nolen WA, Altshuler LL, Rush AJ, Kupka R, Frye MA, Autio KA, Post RM. Early physical and sexual abuse associated with an adverse course of bipolar illness. Biol Psychiatry. 2002 Feb 15; 51(4):288-97. PMID: 11958779.
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    178. Rasgon NL, Altshuler LL, Fairbanks LA, Dunkin JJ, Davtyan C, Elman S, Rapkin AJ. Estrogen replacement therapy in the treatment of major depressive disorder in perimenopausal women. J Clin Psychiatry. 2002; 63 Suppl 7:45-8. PMID: 11995778.
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    179. Altshuler LL. The use of SSRIs in depressive disorders specific to women. J Clin Psychiatry. 2002; 63 Suppl 7:3-8. PMID: 11995776.
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    180. Altshuler LL, Hendrick V, Cohen LS. An Update on Mood and Anxiety Disorders During Pregnancy and the Postpartum Period. Prim Care Companion J Clin Psychiatry. 2000 Dec; 2(6):217-222. PMID: 15014632.
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