Manish J Butte

Title(s)Professor, Pediatrics
SchoolMedicine
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    Other Positions
    Title(s)Professor, MIMG

    Title(s)Professor, Human Genetics


    Collapse Biography 
    Collapse Education and Training
    Brown University, Providence, RIScB05/1993Physics
    Brown University, Providence, RIMD05/1996Medicine
    UCSF, San Fransisco, CAPhD12/2000Biophysics
    Children's Hospital of Philadelphia, Philadelphia, PA05/2003Residency in Pediatrics
    Boston Children's Hospital, Boston, MA05/2006Fellowship in Allergy and Immunology
    Collapse Awards and Honors
    American Society of Clinical Investigation2021Elected Member
    Clinical Immunology Society2021Elected Fellow
    UCLA2019E. Richard Stiehm Endowed Chair

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Collaborative multi-site project to speed the identification and management of rare genetic immune diseases
    NIH R01AI153827Feb 25, 2021 - Jan 31, 2026
    Role: Principal Investigator
    T-cell Dysfunction as the basis of Disseminated Coccidioidomycosis
    NIH R21AI149654Feb 2, 2021 - Jan 31, 2023
    Role: Principal Investigator
    Influences of Nanomechanical Forces on T Cell Activation and Effector Function
    NIH R01GM110482Sep 25, 2014 - Aug 31, 2020
    Role: Principal Investigator
    Microfluidic diagnostics for Primary Immunodeficiency
    NIH R21AI090448Jun 7, 2010 - Nov 30, 2012
    Role: Principal Investigator
    Mechanisms of T cell inhibitory pathways
    NIH K08AI079268Jul 27, 2009 - May 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Twitter
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. APDS patients with immune-complex vasculitis and resolution with leniolisib. Clin Immunol. 2024 Mar 08; 262:110176. Doroudchi MA, Stephens AV, Wang Z, Dhami J, Butte MJ. PMID: 38462154.
      View in: PubMed   Mentions:    Fields:    
    2. Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. ACS Nano. 2024 Feb 21. Hasani-Sadrabadi MM, Majedi FS, Zarubova J, Thauland TJ, Arumugaswami V, Hsiai TK, Bouchard LS, Butte MJ, Li S. PMID: 38381620.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Anifrolumab to treat a monogenic interferonopathy. J Allergy Clin Immunol Pract. 2024 Feb 17. Dorodouchi MA, Thauland TJ, Patel BA, Butte MJ. PMID: 38373653.
      View in: PubMed   Mentions:    Fields:    
    4. Proceedings from the inaugural Artificial Intelligence in Primary Immune Deficiencies (AIPID) conference. J Allergy Clin Immunol. 2024 Mar; 153(3):637-642. Rivière JG, Soler Palacín P, Butte MJ. PMID: 38224784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. Genome Med. 2024 Jan 06; 16(1):6. Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Tayoun AA, Aiuti A, Darazam IA, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, Zein LE, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoglu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Akcan OM, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, von Bernuth H, Lermine A, Vidaud M, Boland A, Deleuze JF, Nussbaum R, Kahn-Kirby A, Mentre F, Tubiana S, Gorochov G, Tubach F, Hausfater P, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Meyts I, Zhang SY, Puel A, Notarangelo LD, Boisson-Dupuis S, Su HC, Boisson B, Jouanguy E, Casanova JL, Zhang Q, Abel L, Cobat A. PMID: 38184654; PMCID: PMC10771638.
      View in: PubMed   Mentions:    Fields:    
    6. Whole blood transcriptomics identifies subclasses of pediatric septic shock. Crit Care. 2023 Dec 08; 27(1):486. Yang JO, Zinter MS, Pellegrini M, Wong MY, Gala K, Markovic D, Nadel B, Peng K, Do N, Mangul S, Nadkarni VM, Karlsberg A, Deshpande D, Butte MJ, Asaro L, Agus M, Sapru A, Study Site Investigators for CAF-PINT. PMID: 38066613; PMCID: PMC10709863.
      View in: PubMed   Mentions:    Fields:    
    7. A Clinicopathological Categorization System for Clinical Research in Coccidioidomycosis. Open Forum Infect Dis. 2023 Dec; 10(12):ofad597. Krogstad P, Thompson GR, Heidari A, Kuran R, Stephens AV, Butte MJ, Johnson R. PMID: 38156047; PMCID: PMC10753911.
      View in: PubMed   Mentions: 1  
    8. Whole Blood Transcriptomics Identifies Subclasses of Pediatric Septic Shock. Res Sq. 2023 Aug 28. Yang JO, Zinter MS, Pellegrini M, Wong MY, Gala K, Markovic D, Nadel B, Peng K, Do N, Mangul S, Nadkarni VM, Karlsberg A, Deshpande D, Butte MJ, Asaro L, Agus M, Sapru A. PMID: 37693502; PMCID: PMC10491329.
      View in: PubMed   Mentions: 1  
    9. Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. Genome Med. 2023 04 05; 15(1):22. Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Abou Tayoun A, Aiuti A, Alavi Darazam I, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoglu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Metin Akcan O, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, von Bernuth H, Lermine A, Vidaud M, Boland A, Deleuze JF, Nussbaum R, Kahn-Kirby A, Mentre F, Tubiana S, Gorochov G, Tubach F, Hausfater P, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Meyts I, Zhang SY, Puel A, Notarangelo LD, Boisson-Dupuis S, Su HC, Boisson B, Jouanguy E, Casanova JL, Zhang Q, Abel L, Cobat A. PMID: 37020259; PMCID: PMC10074346.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    10. Common Variable Immunodeficiency Patient Fecal Microbiota Transplant Recapitulates Gut Dysbiosis. Res Sq. 2023 Mar 13. Hajjar J, Voigt A, Conner M, Swennes A, Fowler S, Calarge C, Mendonca D, Armstrong D, Chang CY, Walter J, Butte M, Savidge T, Oh J, Kheradmand F, Petrosino J. PMID: 36993518; PMCID: PMC10055500.
      View in: PubMed   Mentions:
    11. Systemic enhancement of antitumour immunity by peritumourally implanted immunomodulatory macroporous scaffolds. Nat Biomed Eng. 2023 Jan; 7(1):56-71. Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Keswani SG, Li S, Bouchard LS, Butte MJ. PMID: 36550304; PMCID: PMC9940651.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Med. 2022 Nov 16; 14(1):128. Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, Denny CT, Sul JH, Zaitlen N, Arboleda VA, Halperin E, Sankararaman S, Butte MJ, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working G, Lajonchere C, Geschwind DH, Pasaniuc B. PMID: 36384576; PMCID: PMC9670414.
      View in: PubMed   Mentions:    Fields:    
    13. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 11; 18(11):e1010367. Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, Çelik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, Gómez-Carballa A, Rivero-Calle I, Martinón-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultström M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. PMID: 36327219; PMCID: PMC9632827.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    14. Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. medRxiv. 2022 Oct 25. Matuozzo D, Talouarn E, Marchal A, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Zhang P, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Tayoun AA, Aiuti A, Darazam IA, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoglu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Akcan OM, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, Pérez de Diego R, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, von Bernuth H, Lermine A, Vidaud M, Boland A, Deleuze JF, Nussbaum R, Kahn-Kirby A, Mentre F, Tubiana S, Gorochov G, Tubach F, Hausfater P, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Meyts I, Zhang SY, Puel A, Notarangelo LD, Boisson-Dupuis S, Su HC, Boisson B, Jouanguy E, Casanova JL, Zhang Q, Abel L, Cobat A. PMID: 36324795; PMCID: PMC9628204.
      View in: PubMed   Mentions: 1  
    15. Editorial: The cytoskeleton in T cell migration and activation. Front Immunol. 2022; 13:1057533. Butte MJ, Stein JV, Delon J. PMID: 36311712; PMCID: PMC9614363.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Med. 2022 Sep 09; 14(1):104. Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, Denny CT, Sul JH, Zaitlen N, Arboleda VA, Halperin E, Sankararaman S, Butte MJ, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working G, Lajonchere C, Geschwind DH, Pasaniuc B. PMID: 36085083; PMCID: PMC9461263.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    17. Tuning immunity through tissue mechanotransduction. Nat Rev Immunol. 2023 03; 23(3):174-188. Du H, Bartleson JM, Butenko S, Alonso V, Liu WF, Winer DA, Butte MJ. PMID: 35974148; PMCID: PMC9379893.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    18. Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells. Nat Immunol. 2022 08; 23(8):1256-1272. Csomos K, Ujhazi B, Blazso P, Herrera JL, Tipton CM, Kawai T, Gordon S, Ellison M, Wu K, Stowell M, Haynes L, Cruz R, Zakota B, Nguyen J, Altrich M, Geier CB, Sharapova S, Dasso JF, Leiding JW, Smith G, Al-Herz W, de Barros Dorna M, Fadugba O, Fronkova E, Kanderova V, Svaton M, Henrickson SE, Hernandez JD, Kuijpers T, Kandilarova SM, Naumova E, Milota T, Sediva A, Moshous D, Neven B, Saco T, Sargur R, Savic S, Sleasman J, Sunkersett G, Ward BR, Komatsu M, Pittaluga S, Kumanovics A, Butte MJ, Cancro MP, Pillai S, Meffre E, Notarangelo LD, Walter JE. PMID: 35902638; PMCID: PMC9355881.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    19. IL-10 promotes endothelial progenitor cell infiltration and wound healing via STAT3. FASEB J. 2022 07; 36(7):e22298. Short WD, Steen E, Kaul A, Wang X, Olutoye OO, Vangapandu HV, Templeman N, Blum AJ, Moles CM, Narmoneva DA, Crombleholme TM, Butte MJ, Bollyky PL, Keswani SG, Balaji S. PMID: 35670763.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    20. Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene. Front Immunol. 2022; 13:890073. Wang W, Min Q, Lai N, Csomos K, Wang Y, Liu L, Meng X, Sun J, Hou J, Ying W, Zhou Q, Sun B, Hui X, Ujhazi B, Gordon S, Buchbinder D, Schuetz C, Butte M, Walter JE, Wang X, Wang JY. PMID: 35799777; PMCID: PMC9253290.
      View in: PubMed   Mentions: 5     Fields:    
    21. An Updated Survey of SCID Outcomes Without Preconditioning Chemotherapy. J Allergy Clin Immunol Pract. 2022 04; 10(4):1084-1085. Butte MJ, Kobayashi RH. PMID: 35397808.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Biallelic PI4KA variants cause neurological, intestinal and immunological disease. Brain. 2021 12 31; 144(12):3597-3610. Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla MP, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Ward Melver C, Cox H, Elawad M, Marton T, Wakeling MN, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Walsh Vockley C, Butte MJ, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL. PMID: 34415310; PMCID: PMC8719846.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. Corrigendum to "Unraveling the mechanobiology of immune cells" [Curr Opin Biotechnol 66 (2020) 236-245]. Curr Opin Biotechnol. 2022 Feb; 73:387-388. Zhang X, Kim TH, Thauland TJ, Li H, Majedi FS, Ly C, Gu Z, Butte MJ, Rowat AC, Li S. PMID: 34895976; PMCID: PMC8655620.
      View in: PubMed   Mentions:    Fields:    
    24. Immunomodulatory Microneedle Patch for Periodontal Tissue Regeneration. Matter. 2022 Feb 02; 5(2):666-682. Zhang X, Hasani-Sadrabadi MM, Zarubova J, Dashtimighadam E, Haghniaz R, Khademhosseini A, Butte MJ, Moshaverinia A, Aghaloo T, Li S. PMID: 35340559; PMCID: PMC8942382.
      View in: PubMed   Mentions: 19  
    25. Correction to: Expanding the potential genes of inborn errors of immunity through protein interactions. BMC Genomics. 2021 Oct 15; 22(1):745. Khan HA, Butte MJ. PMID: 34654376; PMCID: PMC8520209.
      View in: PubMed   Mentions:    Fields:    
    26. Expanding the potential genes of inborn errors of immunity through protein interactions. BMC Genomics. 2021 Aug 15; 22(1):618. Khan HA, Butte MJ. PMID: 34391382; PMCID: PMC8364696.
      View in: PubMed   Mentions: 1     Fields:    
    27. Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples. Nat Biomed Eng. 2021 07; 5(7):657-665. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Sina Booeshaghi A, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 34211145; PMCID: PMC10810734.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    28. Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing. medRxiv. 2021 Mar 09. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Booeshaghi AS, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 32909008; PMCID: PMC7480060.
      View in: PubMed   Mentions: 2  
    29. Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors. iScience. 2021 Mar 19; 24(3):102188. Chang TS, Ding Y, Freund MK, Johnson R, Schwarz T, Yabu JM, Hazlett C, Chiang JN, Wulf DA, UCLA Precision Health Data Discovery Repository Working Group, Geschwind DH, Butte MJ, Pasaniuc B. PMID: 33615196; PMCID: PMC7879099.
      View in: PubMed   Mentions: 8  
    30. The New "Wholly Trinity" in the Diagnosis and Management of Inborn Errors of Immunity. J Allergy Clin Immunol Pract. 2021 02; 9(2):613-625. Abraham RS, Butte MJ. PMID: 33551037.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Correction to: Infections in Infants with SCID: Isolation, Infection Screening and Prophylaxis in PIDTC Centers. J Clin Immunol. 2021 Feb; 41(2):498-500. Dorsey M, Wright NAM, Chaimowitz NS, Dávila Saldaña BJ, Miller H, Keller MD, Thakar MS, Shah AJ, Abu-Arja R, Andolina J, Aquino V, Barnum JL, Bednarski JJ, Bhatia M, Bonilla FA, Butte MJ, Bunin NJ, Burroughs LM, Chandra S, Chaudhury S, Chen K, Chong H, Cuvelier G, Dalal J, DeFelice ML, DeSantes KB, Forbes LR, Gillio A, Goldman F, Joshi AY, Kapoor N, Knutsen AP, Kobrynski L, Lieberman JA, Leiding JW, Oshrine B, Patel KP, Prockop S, Quigg TC, Quinones R, Schultz KR, Seroogy C, Shyr D, Siegel S, Smith AR, Torgerson TR, Vander Lugt MT, Yu LC, Cowan MJ, Buckley RH, Dvorak CC, Griffith LM, Haddad E, Kohn DB, Logan B, Notarangelo LD, Pai SY, Puck J, Pulsipher MA, Heimall J. PMID: 33274413.
      View in: PubMed   Mentions:    Fields:    
    32. When Screening for Severe Combined Immunodeficiency (SCID) with T Cell Receptor Excision Circles Is Not SCID: a Case-Based Review. J Clin Immunol. 2021 02; 41(2):294-302. Buchbinder D, Walter JE, Butte MJ, Chan WY, Chitty Lopez M, Dimitriades VR, Dorsey MJ, Nugent DJ, Puck JM, Singh J, Collins CA. PMID: 33411155; PMCID: PMC8179373.
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    33. Commercial immunoglobulin products contain cross-reactive but not neutralizing antibodies against SARS-CoV-2. J Allergy Clin Immunol. 2021 03; 147(3):876-877. Ahn TS, Han B, Krogstad P, Bun C, Kohn LA, Garcia-Lloret MI, Damoiseaux R, Butte MJ. PMID: 33358557; PMCID: PMC7833834.
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    34. Multiplexed Functional Assessment of Genetic Variants in CARD11. Am J Hum Genet. 2020 12 03; 107(6):1029-1043. Meitlis I, Allenspach EJ, Bauman BM, Phan IQ, Dabbah G, Schmitt EG, Camp ND, Torgerson TR, Nickerson DA, Bamshad MJ, Hagin D, Luthers CR, Stinson JR, Gray J, Lundgren I, Church JA, Butte MJ, Jordan MB, Aceves SS, Schwartz DM, Milner JD, Schuval S, Skoda-Smith S, Cooper MA, Starita LM, Rawlings DJ, Snow AL, James RG. PMID: 33202260; PMCID: PMC7820631.
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    35. MPEG1/Perforin-2 Haploinsufficiency Associated Polymicrobial Skin Infections and Considerations for Interferon-γ Therapy. Front Immunol. 2020; 11:601584. Merselis LC, Jiang SY, Nelson SF, Lee H, Prabaker KK, Baker JL, Munson GP, Butte MJ. PMID: 33224153; PMCID: PMC7670069.
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    36. CADINS in an Adult with Chronic Sinusitis and Atopic Disease. J Clin Immunol. 2021 01; 41(1):256-258. Izadi N, Bauman BM, Dabbah G, Thauland TJ, Butte MJ, Snow AL, Church JA. PMID: 33057950.
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    37. Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers. J Clin Immunol. 2021 01; 41(1):38-50. Dorsey MJ, Wright NAM, Chaimowitz NS, Dávila Saldaña BJ, Miller H, Keller MD, Thakar MS, Shah AJ, Abu-Arja R, Andolina J, Aquino V, Barnum JL, Bednarski JJ, Bhatia M, Bonilla FA, Butte MJ, Bunin NJ, Chandra S, Chaudhury S, Chen K, Chong H, Cuvelier GDE, Dalal J, DeFelice ML, DeSantes KB, Forbes LR, Gillio A, Goldman F, Joshi AY, Kapoor N, Knutsen AP, Kobrynski L, Lieberman JA, Leiding JW, Oshrine B, Patel KP, Prockop S, Quigg TC, Quinones R, Schultz KR, Seroogy C, Shyr D, Siegel S, Smith AR, Torgerson TR, Vander Lugt MT, Yu LC, Cowan MJ, Buckley RH, Dvorak CC, Griffith LM, Haddad E, Kohn DB, Logan B, Notarangelo LD, Pai SY, Puck J, Pulsipher MA, Heimall J. PMID: 33006109; PMCID: PMC8388237.
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    38. Unraveling the mechanobiology of immune cells. Curr Opin Biotechnol. 2020 12; 66:236-245. Zhang X, Kim TH, Thauland TJ, Li H, Majedi FS, Ly C, Gu Z, Butte MJ, Rowat AC, Li S. PMID: 33007634; PMCID: PMC7524653.
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    39. Augmenting T-cell responses to tumors by in situ nanomanufacturing. Mater Horiz. 2020 Nov 01; 7(11):3028-3033. Hasani-Sadrabadi MM, Majedi FS, Miller ML, Thauland TJ, Bouchard LS, Li S, Butte MJ. PMID: 33343906; PMCID: PMC7748250.
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    40. Mechanosensing through YAP controls T cell activation and metabolism. J Exp Med. 2020 08 03; 217(8). Meng KP, Majedi FS, Thauland TJ, Butte MJ. PMID: 32484502; PMCID: PMC7398163.
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    41. Progressive B Cell Loss in Revertant X-SCID. J Clin Immunol. 2020 10; 40(7):1001-1009. Lin CH, Kuehn HS, Thauland TJ, Lee CM, De Ravin SS, Malech HL, Keyes TJ, Jager A, Davis KL, Garcia-Lloret MI, Rosenzweig SD, Butte MJ. PMID: 32681206; PMCID: PMC7508923.
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    42. Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System. medRxiv. 2020 Jul 09. Chang TS, Ding Y, Freund MK, Johnson R, Schwarz T, Yabu JM, Hazlett C, Chiang JN, Wulf A, UCLA Health Data Mart Working Group, Geschwind DH, Butte MJ, Pasaniuc B. PMID: 32637977; PMCID: PMC7340203.
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    43. Disseminated Coccidioidomycosis Treated with Interferon-γ and Dupilumab. N Engl J Med. 2020 06 11; 382(24):2337-2343. Tsai M, Thauland TJ, Huang AY, Bun C, Fitzwater S, Krogstad P, Douine ED, Nelson SF, Lee H, Garcia-Lloret MI, Butte MJ. PMID: 32521134; PMCID: PMC7333509.
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    46. CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells. Sci Adv. 2020 05; 6(19):eaaz0571. Goodwin M, Lee E, Lakshmanan U, Shipp S, Froessl L, Barzaghi F, Passerini L, Narula M, Sheikali A, Lee CM, Bao G, Bauer CS, Miller HK, Garcia-Lloret M, Butte MJ, Bertaina A, Shah A, Pavel-Dinu M, Hendel A, Porteus M, Roncarolo MG, Bacchetta R. PMID: 32494707; PMCID: PMC7202871.
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    49. The Role of the Anti-Inflammatory Cytokine Interleukin-10 in Tissue Fibrosis. Adv Wound Care (New Rochelle). 2020 04 01; 9(4):184-198. Steen EH, Wang X, Balaji S, Butte MJ, Bollyky PL, Keswani SG. PMID: 32117582; PMCID: PMC7047112.
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    50. The Actin-Capping Protein Alpha-Adducin Is Required for T-Cell Costimulation. Front Immunol. 2019; 10:2706. Thauland TJ, Khan HA, Butte MJ. PMID: 31824498; PMCID: PMC6879651.
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    51. Differential Contributions of Actin and Myosin to the Physical Phenotypes and Invasion of Pancreatic Cancer Cells. Cell Mol Bioeng. 2020 Feb; 13(1):27-44. Nguyen AV, Trompetto B, Tan XHM, Scott MB, Hu KH, Deeds E, Butte MJ, Chiou PY, Rowat AC. PMID: 32030106; PMCID: PMC6981337.
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    53. T Lymphocytes Attenuate Dermal Scarring by Regulating Inflammation, Neovascularization, and Extracellular Matrix Remodeling. Adv Wound Care (New Rochelle). 2019 Nov 01; 8(11):527-537. Wang X, Balaji S, Steen EH, Li H, Rae MM, Blum AJ, Miao Q, Butte MJ, Bollyky PL, Keswani SG. PMID: 31637099; PMCID: PMC6798809.
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    57. Treatment of systemic mastocytosis in an infant with midostaurin. J Allergy Clin Immunol Pract. 2019 Nov - Dec; 7(8):2929-2931.e1. Liu MM, Kohn LA, Roach GD, Sun G, Garcia-Lloret MI, Butte MJ. PMID: 31154031.
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    60. Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017. Pediatrics. 2019 02; 143(2). Amatuni GS, Currier RJ, Church JA, Bishop T, Grimbacher E, Nguyen AA, Agarwal-Hashmi R, Aznar CP, Butte MJ, Cowan MJ, Dorsey MJ, Dvorak CC, Kapoor N, Kohn DB, Markert ML, Moore TB, Naides SJ, Sciortino S, Feuchtbaum L, Koupaei RA, Puck JM. PMID: 30683812; PMCID: PMC6361357.
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    62. Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency. J Allergy Clin Immunol. 2018 06; 141(6):2303-2306. Lawless D, Geier CB, Farmer JR, Lango Allen H, Thwaites D, Atschekzei F, Brown M, Buchbinder D, Burns SO, Butte MJ, Csomos K, Deevi SVV, Egner W, Ehl S, Eibl MM, Fadugba O, Foldvari Z, Green DM, Henrickson SE, Holland SM, John T, Klemann C, Kuijpers TW, Moreira F, Piller A, Rayner-Matthews P, Romberg ND, Sargur R, Schmidt RE, Schröder C, Schuetz C, Sharapova SO, Smith KGC, Sogkas G, Speckmann C, Stirrups K, Thrasher AJ, Wolf HM, Notarangelo LD, Anwar R, Boyes J, Ujhazi B, NIHR BioResource–Rare Diseases Consortium, Thaventhiran J, Walter JE, Savic S. PMID: 29477728; PMCID: PMC6058308.
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    63. Cytokine Secreting Microparticles Engineer the Fate and the Effector Functions of T-Cells. Adv Mater. 2018 Feb; 30(7). Majedi FS, Hasani-Sadrabadi MM, Kidani Y, Thauland TJ, Moshaverinia A, Butte MJ, Bensinger SJ, Bouchard LS. PMID: 29315824; PMCID: PMC5854475.
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    64. Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. J Biol Chem. 2018 01 12; 293(2):567-578. Nagy N, de la Zerda A, Kaber G, Johnson PY, Hu KH, Kratochvil MJ, Yadava K, Zhao W, Cui Y, Navarro G, Annes JP, Wight TN, Heilshorn SC, Bollyky PL, Butte MJ. PMID: 29183997; PMCID: PMC5767862.
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    65. Quantitative Deformability Cytometry: Rapid, Calibrated Measurements of Cell Mechanical Properties. Biophys J. 2017 Oct 03; 113(7):1574-1584. Nyberg KD, Hu KH, Kleinman SH, Khismatullin DB, Butte MJ, Rowat AC. PMID: 28978449; PMCID: PMC5627151.
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    66. Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):E3709-E3718. Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ. PMID: 28420791; PMCID: PMC5422809.
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    67. Systems approach to uncover signaling networks in primary immunodeficiency diseases. J Allergy Clin Immunol. 2017 09; 140(3):881-884.e8. Choi J, Fernandez R, Maecker HT, Butte MJ. PMID: 28412396; PMCID: PMC5591762.
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    77. Winner of the Young Investigator Award of the Society for Biomaterials at the 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model. J Biomed Mater Res A. 2016 06; 104(6):1321-31. Han LH, Conrad B, Chung MT, Deveza L, Jiang X, Wang A, Butte MJ, Longaker MT, Wan D, Yang F. PMID: 26991141; PMCID: PMC5142823.
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