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Hewison, Martin

Title(s)Adjunct Professor, Orthopaedic Surgery
Phone3103191234
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    Collapse Research 
    Collapse Research Activities and Funding
    DBP and the bioavailability and function of vitamin D
    NIH/NIAMS R01AR063910Sep 1, 2013 - May 31, 2018
    Role: Co-Principal Investigator
    FGF23 and the regulation of vitamin D-induced immunity in CKD
    NIH/NIDDK R21DK091672May 15, 2012 - Apr 30, 2014
    Role: Principal Investigator
    Vitamin D and Barrier Function
    NIH/NIAMS R01AR050626Jul 26, 2004 - Nov 2, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hassan-Smith Z, Hewison M, Gittoes N. Vitamin D Supplementation and Prevention of Type 2 Diabetes. N Engl J Med. 2019 10 31; 381(18):1784-1785. PMID: 31665588.
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    2. Chun RF, Shieh A, Gottlieb C, Yacoubian V, Wang J, Hewison M, Adams JS. Vitamin D Binding Protein and the Biological Activity of Vitamin D. Front Endocrinol (Lausanne). 2019; 10:718. PMID: 31708871.
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    3. Fletcher J, Cooper SC, Ghosh S, Hewison M. The Role of Vitamin D in Inflammatory Bowel Disease: Mechanism to Management. Nutrients. 2019 May 07; 11(5). PMID: 31067701.
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    4. Muñoz García A, Eijssen LM, Kutmon M, Sarathy C, Cengo A, Hewison M, Evelo CT, Lenz M, Coort SL. A bioinformatics workflow to decipher transcriptomic data from vitamin D studies. J Steroid Biochem Mol Biol. 2019 05; 189:28-35. PMID: 30716464.
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    5. Li D, Jeffery LE, Jenkinson C, Harrison SR, Chun RF, Adams JS, Raza K, Hewison M. Serum and synovial fluid vitamin D metabolites and rheumatoid arthritis. J Steroid Biochem Mol Biol. 2019 03; 187:1-8. PMID: 30611909.
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    6. Hewison M, Wagner CL, Hollis BW. Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth. N Engl J Med. 2018 11 08; 379(19):1880-1. PMID: 30406981.
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    7. Zavala K, Gottlieb CA, Teles RM, Adams JS, Hewison M, Modlin RL, Liu PT. Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN. PLoS Negl Trop Dis. 2018 10; 12(10):e0006815. PMID: 30300363.
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    8. Shieh A, Ma C, Chun RF, Wittwer-Schegg J, Swinkels L, Huijs T, Wang J, Donangelo I, Hewison M, Adams JS. Associations Between Change in Total and Free 25-Hydroxyvitamin D With 24,25-Dihydroxyvitamin D and Parathyroid Hormone. J Clin Endocrinol Metab. 2018 09 01; 103(9):3368-3375. PMID: 29931358.
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    9. Jenkinson C, Taylor AE, Storbeck KH, Hewison M. Data comparing the separation and elution of vitamin D metabolites on an ultra performance supercritical fluid chromatography tandem-mass spectrometer (UPSFC-MS/MS) compared to liquid chromatography (LC) and data presenting approaches to UPSFC method optimization. Data Brief. 2018 Oct; 20:426-435. PMID: 30175209.
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    10. Hewison M. The earlier the better: preconception vitamin D and protection against pregnancy loss. Lancet Diabetes Endocrinol. 2018 09; 6(9):680-681. PMID: 29884467.
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    11. Sum M, Larner D, Hewison M, Bilezikian JP. Brown tumors of primary hyperparathyroidism may be a source of extrarenal 1,25-dihydroxyvitamin D production. Endocrine. 2018 06; 60(3):524-527. PMID: 29556950.
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    12. Muñoz Garcia A, Kutmon M, Eijssen L, Hewison M, Evelo CT, Coort SL. Pathway analysis of transcriptomic data shows immunometabolic effects of vitamin D. J Mol Endocrinol. 2018 02; 60(2):95-108. PMID: 29233860.
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    13. Hewison M, Fleet JC, Demay MB, Christakos S, Bouillon R, Welsh J, White JH. Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28-31, 2017. J Steroid Biochem Mol Biol. 2018 03; 177:1-5. PMID: 29180166.
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    14. Ganguly A, Tamblyn JA, Finn-Sell S, Chan SY, Westwood M, Gupta J, Kilby MD, Gross SR, Hewison M. Vitamin D, the placenta and early pregnancy: effects on trophoblast function. J Endocrinol. 2018 02; 236(2):R93-R103. PMID: 29109081.
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    15. Christakos S, White JH, Hewison M, Welsh J, Lips P, Bouillon R, Demay MB. Highlights from the 19th Workshop on Vitamin D in Boston, March 29-31, 2016. J Steroid Biochem Mol Biol. 2017 10; 173:1-4. PMID: 28895872.
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    16. Liu NQ, Larner DP, Yao Q, Chun RF, Ouyang Y, Zhou R, Tamblyn JA, Wagner CL, Hewison M. Vitamin D-deficiency and sex-specific dysregulation of placental inflammation. J Steroid Biochem Mol Biol. 2018 03; 177:223-230. PMID: 28676458.
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    17. Hassan-Smith ZK, Hewison M, Gittoes NJ. Effect of vitamin D deficiency in developed countries. Br Med Bull. 2017 06 01; 122(1):79-89. PMID: 28334220.
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    18. Shieh A, Ma C, Chun RF, Witzel S, Rafison B, Contreras HTM, Wittwer-Schegg J, Swinkels L, Huijs T, Hewison M, Adams JS. Effects of Cholecalciferol vs Calcifediol on Total and Free 25-Hydroxyvitamin D and Parathyroid Hormone. J Clin Endocrinol Metab. 2017 Apr 01; 102(4):1133-1140. PMID: 28187226.
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    19. Zhao H, Rieger S, Abe K, Hewison M, Lisse TS. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization. Int J Mol Sci. 2016 Nov 26; 17(12). PMID: 27898044.
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    20. Zhou R, Park JW, Chun RF, Lisse TS, Garcia AJ, Zavala K, Sea JL, Lu ZX, Xu J, Adams JS, Xing Y, Hewison M. Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells. Nucleic Acids Res. 2017 01 25; 45(2):606-618. PMID: 27672039.
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    21. Chun RF, Hernandez I, Pereira R, Swinkles L, Huijs T, Zhou R, Liu NQ, Shieh A, Guemes M, Mallya SM, Adams JS, Hewison M. Differential Responses to Vitamin D2 and Vitamin D3 Are Associated With Variations in Free 25-Hydroxyvitamin D. Endocrinology. 2016 09; 157(9):3420-30. PMID: 27399876.
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    22. Shieh A, Chun RF, Ma C, Witzel S, Meyer B, Rafison B, Swinkels L, Huijs T, Pepkowitz S, Holmquist B, Hewison M, Adams JS. Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance. J Clin Endocrinol Metab. 2016 08; 101(8):3070-8. PMID: 27192696.
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    23. Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Schepmoes AA, Zmuda JM, Lapidus J, Cauley JA, Bouillon R, Schoenmakers I, Orwoll ES. Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations. J Clin Endocrinol Metab. 2016 05; 101(5):2226-34. PMID: 27007693.
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    24. Nielson CM, Jones KS, Bouillon R, Chun RF, Jacobs J, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Zmuda JM, Lapidus J, Cauley JA, Schoenmakers I, Orwoll ES. Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations. N Engl J Med. 2016 Apr 28; 374(17):1695-6. PMID: 27007809.
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    25. Huish SA, Fletcher S, Dunn JA, Hewison M, Bland R. Prevalence and treatment of hypovitaminosis D in the haemodialysis population of Coventry. J Steroid Biochem Mol Biol. 2016 11; 164:214-217. PMID: 26877202.
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    26. Jenkinson C, Taylor AE, Hassan-Smith ZK, Adams JS, Stewart PM, Hewison M, Keevil BG. High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 01; 1014:56-63. PMID: 26874878.
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    27. Sarkar S, Hewison M, Studzinski GP, Li YC, Kalia V. Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer. Crit Rev Clin Lab Sci. 2016; 53(2):132-45. PMID: 26479950.
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    28. Jeffery LE, Raza K, Hewison M. Vitamin D in rheumatoid arthritis-towards clinical application. Nat Rev Rheumatol. 2016 Apr; 12(4):201-10. PMID: 26481434.
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    29. Bacchetta J, Chun RF, Gales B, Zaritsky JJ, Leroy S, Wesseling-Perry K, Boregaard N, Rastogi A, Salusky IB, Hewison M. Antibacterial responses by peritoneal macrophages are enhanced following vitamin D supplementation. PLoS One. 2014; 9(12):e116530. PMID: 25549329.
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    30. Zhou R, Chun RF, Lisse TS, Garcia AJ, Xu J, Adams JS, Hewison M. Vitamin D and alternative splicing of RNA. J Steroid Biochem Mol Biol. 2015 Apr; 148:310-7. PMID: 25447737.
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    31. Chun RF, Blatter E, Elliott S, Fitz-Gibbon S, Rieger S, Sagasti A, Adams JS, Hewison M. Cloning of a functional 25-hydroxyvitamin D-1a-hydroxylase in zebrafish (Danio rerio). Cell Biochem Funct. 2014 Dec; 32(8):675-82. PMID: 25290078.
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    32. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20; 6(250):250ra114. PMID: 25143364.
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    33. Chun RF, Liu NQ, Lee T, Schall JI, Denburg MR, Rutstein RM, Adams JS, Zemel BS, Stallings VA, Hewison M. Vitamin D supplementation and antibacterial immune responses in adolescents and young adults with HIV/AIDS. J Steroid Biochem Mol Biol. 2015 Apr; 148:290-7. PMID: 25092518.
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    34. Chun RF, Liu PT, Modlin RL, Adams JS, Hewison M. Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Front Physiol. 2014; 5:151. PMID: 24795646.
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    35. Lisse TS, Vadivel K, Bajaj SP, Chun RF, Hewison M, Adams JS. The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts. Bone Res. 2014; 2. PMID: 25506471.
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    36. Adams JS, Rafison B, Witzel S, Reyes RE, Shieh A, Chun R, Zavala K, Hewison M, Liu PT. Regulation of the extrarenal CYP27B1-hydroxylase. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:22-7. PMID: 24388948.
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    37. Sylvester FA, Gordon CM, Thayu M, Burnham JM, Denson LA, Essers J, Ferrari S, Gupta N, Hewison M, Koletzko S, McCabe L, Pappa H, Sanderson I, Ward L, Zanotti S. Report of the CCFA pediatric bone, growth and muscle health workshop, New York City, November 11-12, 2011, with updates. Inflamm Bowel Dis. 2013 Dec; 19(13):2919-26. PMID: 23974992.
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    38. Bacchetta J, Zaritsky JJ, Sea JL, Chun RF, Lisse TS, Zavala K, Nayak A, Wesseling-Perry K, Westerman M, Hollis BW, Salusky IB, Hewison M. Suppression of iron-regulatory hepcidin by vitamin D. J Am Soc Nephrol. 2014 Mar; 25(3):564-72. PMID: 24204002.
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    39. Chun RF, Peercy BE, Orwoll ES, Nielson CM, Adams JS, Hewison M. Vitamin D and DBP: the free hormone hypothesis revisited. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:132-7. PMID: 24095930.
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    40. Lisse TS, Chun RF, Rieger S, Adams JS, Hewison M. Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts. J Bone Miner Res. 2013 Jun; 28(6):1478-88. PMID: 23362149.
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    41. Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, Rutten E, Pittas AG, Boland R, Ferrucci L, Bikle DD. Vitamin D: beyond bone. Ann N Y Acad Sci. 2013 May; 1287:45-58. PMID: 23682710.
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    42. Liu NQ, Ouyang Y, Bulut Y, Lagishetty V, Chan SY, Hollis BW, Wagner C, Equils O, Hewison M. Dietary vitamin D restriction in pregnant female mice is associated with maternal hypertension and altered placental and fetal development. Endocrinology. 2013 Jul; 154(7):2270-80. PMID: 23677931.
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    43. Moraitis AG, Hewison M, Collins M, Anaya C, Holick MF. Hypercalcemia associated with mineral oil-induced sclerosing paraffinomas. Endocr Pract. 2013 Mar-Apr; 19(2):e50-6. PMID: 23337133.
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    44. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22; 339(6126):1448-53. PMID: 23449998.
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    45. Pervin S, Hewison M, Braga M, Tran L, Chun R, Karam A, Chaudhuri G, Norris K, Singh R. Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy. PLoS One. 2013; 8(1):e53287. PMID: 23341935.
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    46. Lisse TS, Adams JS, Hewison M. Vitamin D and microRNAs in bone. Crit Rev Eukaryot Gene Expr. 2013; 23(3):195-214. PMID: 23879537.
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    47. Bacchetta J, Sea JL, Chun RF, Lisse TS, Wesseling-Perry K, Gales B, Adams JS, Salusky IB, Hewison M. Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res. 2013 Jan; 28(1):46-55. PMID: 22886720.
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    48. Bacchetta J, Salusky IB, Hewison M. Beyond mineral metabolism, is there an interplay between FGF23 and vitamin D in innate immunity? Pediatr Nephrol. 2013 Apr; 28(4):577-82. PMID: 23117582.
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    49. Ahasan MM, Hardy R, Jones C, Kaur K, Nanus D, Juarez M, Morgan SA, Hassan-Smith Z, Bénézech C, Caamaño JH, Hewison M, Lavery G, Rabbitt EH, Clark AR, Filer A, Buckley CD, Raza K, Stewart PM, Cooper MS. Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells. Arthritis Rheum. 2012 Jul; 64(7):2404-13. PMID: 22294469.
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    50. Gold SM, Sasidhar MV, Lagishetty V, Spence RD, Umeda E, Ziehn MO, Krieger T, Schulz KH, Heesen C, Hewison M, Voskuhl RR. Dynamic development of glucocorticoid resistance during autoimmune neuroinflammation. J Clin Endocrinol Metab. 2012 Aug; 97(8):E1402-10. PMID: 22659246.
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    51. Hewison M. Vitamin D and the immune system: new perspectives on an old theme. Rheum Dis Clin North Am. 2012 Feb; 38(1):125-39. PMID: 22525848.
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    52. Hewison M. An update on vitamin D and human immunity. Clin Endocrinol (Oxf). 2012 Mar; 76(3):315-25. PMID: 21995874.
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    53. Chun RF, Peercy BE, Adams JS, Hewison M. Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling. PLoS One. 2012; 7(1):e30773. PMID: 22292037.
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    54. Hewison M. Vitamin D and immune function: autocrine, paracrine or endocrine? Scand J Clin Lab Invest Suppl. 2012; 243:92-102. PMID: 22536769.
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    55. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med. 2011 Oct 12; 3(104):104ra102. PMID: 21998409.
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    56. Chun RF, Adams JS, Hewison M. Immunomodulation by vitamin D: implications for TB. Expert Rev Clin Pharmacol. 2011 Sep; 4(5):583-91. PMID: 22046197.
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    57. Hewison M. Vitamin D and immune function: an overview. Proc Nutr Soc. 2012 Feb; 71(1):50-61. PMID: 21849106.
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    58. Lagishetty V, Liu NQ, Hewison M. Vitamin D metabolism and innate immunity. Mol Cell Endocrinol. 2011 Dec 05; 347(1-2):97-105. PMID: 21664425.
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    59. Liu NQ, Kaplan AT, Lagishetty V, Ouyang YB, Ouyang Y, Simmons CF, Equils O, Hewison M. Vitamin D and the regulation of placental inflammation. J Immunol. 2011 May 15; 186(10):5968-74. PMID: 21482732.
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    60. Hewison M. Antibacterial effects of vitamin D. Nat Rev Endocrinol. 2011 Jun; 7(6):337-45. PMID: 21263449.
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    61. Lisse TS, Hewison M, Adams JS. Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling. Steroids. 2011 Mar; 76(4):331-9. PMID: 21236284.
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    62. Hewison M. Vitamin D and innate and adaptive immunity. Vitam Horm. 2011; 86:23-62. PMID: 21419266.
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    63. Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL. T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22593-8. PMID: 21149724.
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    64. Lisse TS, Liu T, Irmler M, Beckers J, Chen H, Adams JS, Hewison M. Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling. FASEB J. 2011 Mar; 25(3):937-47. PMID: 21123297.
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    65. Bhan I, Hewison M, Thadhani R. Dietary vitamin D intake in advanced CKD/ESRD. Semin Dial. 2010 Jul-Aug; 23(4):407-10. PMID: 20701720.
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    66. Equils O, Hewison M. A role for vitamin D in placental immunology. J Infect Dis. 2010 Jun 15; 201(12):1950-1; author reply 1951. PMID: 20470053.
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    67. Hewison M. Vitamin D and the immune system: new perspectives on an old theme. Endocrinol Metab Clin North Am. 2010 Jun; 39(2):365-79, table of contents. PMID: 20511058.
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    68. Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, Martineau AR, Wilkinson RJ, Adams J, Hewison M. Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab. 2010 Jul; 95(7):3368-76. PMID: 20427486.
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    69. Kallas M, Green F, Hewison M, White C, Kline G. Rare causes of calcitriol-mediated hypercalcemia: a case report and literature review. J Clin Endocrinol Metab. 2010 Jul; 95(7):3111-7. PMID: 20427501.
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    70. Lagishetty V, Misharin AV, Liu NQ, Lisse TS, Chun RF, Ouyang Y, McLachlan SM, Adams JS, Hewison M. Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis. Endocrinology. 2010 Jun; 151(6):2423-32. PMID: 20392825.
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    71. Hewison M. Vitamin D and the intracrinology of innate immunity. Mol Cell Endocrinol. 2010 Jun 10; 321(2):103-11. PMID: 20156523.
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    72. Lagishetty V, Chun RF, Liu NQ, Lisse TS, Adams JS, Hewison M. 1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):228-33. PMID: 20152900.
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    73. Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab. 2010 Feb; 95(2):471-8. PMID: 20133466.
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    74. Hewison M, Adams JS. Vitamin D insufficiency and skeletal development in utero. J Bone Miner Res. 2010 Jan; 25(1):11-3. PMID: 20091930.
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    75. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe. 2009 Oct 22; 6(4):343-53. PMID: 19837374.
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    76. Adams JS, Ren S, Liu PT, Chun RF, Lagishetty V, Gombart AF, Borregaard N, Modlin RL, Hewison M. Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol. 2009 Apr 01; 182(7):4289-95. PMID: 19299728.
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    77. Masoumi A, Goldenson B, Ghirmai S, Avagyan H, Zaghi J, Abel K, Zheng X, Espinosa-Jeffrey A, Mahanian M, Liu PT, Hewison M, Mizwickie M, Cashman J, Fiala M. 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis. 2009; 17(3):703-17. PMID: 19433889.
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    78. Chen H, Clemens TL, Hewison M, Adams JS. Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro. Endocrinology. 2009 May; 150(5):2429-35. PMID: 19106221.
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    79. Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol. 2008 Nov 15; 181(10):7115-20. PMID: 18981132.
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    80. Lee JM, Pou K, Sadow PM, Chen H, Hu B, Hewison M, Adams JS, Sugarbaker DJ, Fisher ND. Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma. Endocr Pract. 2008 Nov; 14(8):1011-6. PMID: 19095601.
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    81. Misharin A, Hewison M, Chen CR, Lagishetty V, Aliesky HA, Mizutori Y, Rapoport B, McLachlan SM. Vitamin D deficiency modulates Graves' hyperthyroidism induced in BALB/c mice by thyrotropin receptor immunization. Endocrinology. 2009 Feb; 150(2):1051-60. PMID: 18927213.
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    82. Zehnder D, Quinkler M, Eardley KS, Bland R, Lepenies J, Hughes SV, Raymond NT, Howie AJ, Cockwell P, Stewart PM, Hewison M. Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int. 2008 Nov; 74(10):1343-53. PMID: 18784644.
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    83. Liu N, Nguyen L, Chun RF, Lagishetty V, Ren S, Wu S, Hollis B, DeLuca HF, Adams JS, Hewison M. Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology. 2008 Oct; 149(10):4799-808. PMID: 18535110.
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    84. Chun RF, Adams JS, Hewison M. Back to the future: a new look at 'old' vitamin D. J Endocrinol. 2008 Aug; 198(2):261-9. PMID: 18495944.
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    85. Hewison M. Vitamin D and innate immunity. Curr Opin Investig Drugs. 2008 May; 9(5):485-90. PMID: 18465658.
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    86. Adams JS, Hewison M. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab. 2008 Feb; 4(2):80-90. PMID: 18212810.
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    87. Chen H, Hewison M, Adams JS. Control of estradiol-directed gene transactivation by an intracellular estrogen-binding protein and an estrogen response element-binding protein. Mol Endocrinol. 2008 Mar; 22(3):559-69. PMID: 18096692.
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    88. Adams JS, Chen H, Chun R, Ren S, Wu S, Gacad M, Nguyen L, Ride J, Liu P, Modlin R, Hewison M. Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response. J Bone Miner Res. 2007 Dec; 22 Suppl 2:V20-4. PMID: 18290716.
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    89. Adams JS, Liu PT, Chun R, Modlin RL, Hewison M. Vitamin D in defense of the human immune response. Ann N Y Acad Sci. 2007 Nov; 1117:94-105. PMID: 17656563.
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    90. Hewison M, Burke F, Evans KN, Lammas DA, Sansom DM, Liu P, Modlin RL, Adams JS. Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):316-21. PMID: 17368179.
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    91. Chen H, Hewison M, Adams JS. Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element-binding protein. J Biol Chem. 2006 Dec 22; 281(51):39114-20. PMID: 17071612.
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    92. Karakelides H, Geller JL, Schroeter AL, Chen H, Behn PS, Adams JS, Hewison M, Wermers RA. Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase. J Bone Miner Res. 2006 Sep; 21(9):1496-9. PMID: 16939409.
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