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Marsden, Matthew D

Title(s)Associate Adjunct Professor, Medicine
SchoolMed - Hematology And Oncology
Phone51458
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    Collapse Research 
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    Novel method for evaluating HIV latency and persistence in vivo
    NIH/NIAID R21AI124763Feb 10, 2016 - Jan 31, 2018
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Llewellyn GN, Seclén E, Wietgrefe S, Liu S, Chateau M, Pei H, Perkey K, Marsden MD, Hinkley SJ, Paschon DE, Holmes MC, Zack JA, Louie SG, Haase AT, Cannon PM. Humanized Mouse Model of HIV-1 Latency with Enrichment of Latent Virus in PD-1+ and TIGIT+ CD4 T Cells. J Virol. 2019 05 15; 93(10). PMID: 30842333.
      View in: PubMed
    2. Smith SE, Busse DC, Binter S, Weston S, Diaz Soria C, Laksono BM, Clare S, Van Nieuwkoop S, Van den Hoogen BG, Clement M, Marsden M, Humphreys IR, Marsh M, de Swart RL, Wash RS, Tregoning JS, Kellam P. Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane. J Virol. 2019 03 15; 93(6). PMID: 30567988.
      View in: PubMed
    3. Marsden MD, Wu X, Navab SM, Loy BA, Schrier AJ, DeChristopher BA, Shimizu AJ, Hardman CT, Ho S, Ramirez CM, Wender PA, Zack JA. Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents. Virology. 2018 07; 520:83-93. PMID: 29800728.
      View in: PubMed
    4. Marsden MD, Loy BA, Wu X, Ramirez CM, Schrier AJ, Murray D, Shimizu A, Ryckbosch SM, Near KE, Chun TW, Wender PA, Zack JA. In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication. PLoS Pathog. 2017 Sep; 13(9):e1006575. PMID: 28934369.
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    5. Marsden MD, Zack JA. Humanized Mouse Models for Human Immunodeficiency Virus Infection. Annu Rev Virol. 2017 09 29; 4(1):393-412. PMID: 28746819.
      View in: PubMed
    6. Sanchez DJ, Miranda D, Marsden MD, Dizon TM, Bontemps JR, Davila SJ, Del Mundo LE, Ha T, Senaati A, Zack JA, Cheng G. Disruption of Type I Interferon Induction by HIV Infection of T Cells. PLoS One. 2015; 10(9):e0137951. PMID: 26375588.
      View in: PubMed
    7. Shimizu S, Ringpis GE, Marsden MD, Cortado RV, Wilhalme HM, Elashoff D, Zack JA, Chen IS, An DS. RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice. Mol Ther Nucleic Acids. 2015 Feb 17; 4:e227. PMID: 25689223.
      View in: PubMed
    8. Marsden MD, Zack JA. Studies of retroviral infection in humanized mice. Virology. 2015 May; 479-480:297-309. PMID: 25680625.
      View in: PubMed
    9. Marsden MD, Zack JA. Double trouble: HIV latency and CTL escape. Cell Host Microbe. 2015 Feb 11; 17(2):141-2. PMID: 25674977.
      View in: PubMed
    10. Marsden MD, Zack JA. Experimental Approaches for Eliminating Latent HIV. For Immunopathol Dis Therap. 2015; 6(1-2):91-99. PMID: 28191361.
      View in: PubMed
    11. Marsden MD, Zack JA. Neutralizing the HIV reservoir. Cell. 2014 Aug 28; 158(5):971-972. PMID: 25171398.
      View in: PubMed
    12. Buehler DC, Marsden MD, Shen S, Toso DB, Wu X, Loo JA, Zhou ZH, Kickhoefer VA, Wender PA, Zack JA, Rome LH. Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery. ACS Nano. 2014 Aug 26; 8(8):7723-32. PMID: 25061969.
      View in: PubMed
    13. Beans EJ, Fournogerakis D, Gauntlett C, Heumann LV, Kramer R, Marsden MD, Murray D, Chun TW, Zack JA, Wender PA. Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11698-703. PMID: 23812750.
      View in: PubMed
    14. Marsden MD, Zack JA. HIV/AIDS eradication. Bioorg Med Chem Lett. 2013 Jul 15; 23(14):4003-10. PMID: 23735743.
      View in: PubMed
    15. Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity. 2013 Jan 24; 38(1):92-105. PMID: 23273844.
      View in: PubMed
    16. Marsden MD, Krogstad PA, Zack JA. Virological evidence supporting the use of raltegravir in HIV post-exposure prophylaxis regimens. Antivir Ther. 2012; 17(7):1375-9. PMID: 22820096.
      View in: PubMed
    17. DeChristopher BA, Loy BA, Marsden MD, Schrier AJ, Zack JA, Wender PA. Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro. Nat Chem. 2012 Sep; 4(9):705-10. PMID: 22914190.
      View in: PubMed
    18. Marsden MD, Kovochich M, Suree N, Shimizu S, Mehta R, Cortado R, Bristol G, An DS, Zack JA. HIV latency in the humanized BLT mouse. J Virol. 2012 Jan; 86(1):339-47. PMID: 22072769.
      View in: PubMed
    19. Marsden MD, Burke BP, Zack JA. HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes. Virology. 2011 Sep 01; 417(2):394-9. PMID: 21777932.
      View in: PubMed
    20. Marsden MD, Avancena P, Kitchen CM, Hubbard T, Zack JA. Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages. Antimicrob Agents Chemother. 2011 Aug; 55(8):3696-702. PMID: 21628534.
      View in: PubMed
    21. Kovochich M, Marsden MD, Zack JA. Activation of latent HIV using drug-loaded nanoparticles. PLoS One. 2011 Apr 05; 6(4):e18270. PMID: 21483687.
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    22. Marsden MD, Zack JA. Establishment and maintenance of HIV latency: model systems and opportunities for intervention. Future Virol. 2010 Jan 01; 5(1):97-109. PMID: 21318097.
      View in: PubMed
    23. Galic Z, Kitchen SG, Subramanian A, Bristol G, Marsden MD, Balamurugan A, Kacena A, Yang O, Zack JA. Generation of T lineage cells from human embryonic stem cells in a feeder free system. Stem Cells. 2009 Jan; 27(1):100-7. PMID: 18974209.
      View in: PubMed
    24. Subramanian A, Guo B, Marsden MD, Galic Z, Kitchen S, Kacena A, Brown HJ, Cheng G, Zack JA. Macrophage differentiation from embryoid bodies derived from human embryonic stem cells. J Stem Cells. 2009; 4(1):29-45. PMID: 20498689.
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    25. Marsden MD, Zack JA. Eradication of HIV: current challenges and new directions. J Antimicrob Chemother. 2009 Jan; 63(1):7-10. PMID: 18984648.
      View in: PubMed
    26. Marsden MD, Xu J, Hamer D, Zack JA. Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages. AIDS Res Hum Retroviruses. 2008 Nov; 24(11):1399-404. PMID: 19000022.
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    27. Burke B, Brown HJ, Marsden MD, Bristol G, Vatakis DN, Zack JA. Primary cell model for activation-inducible human immunodeficiency virus. J Virol. 2007 Jul; 81(14):7424-34. PMID: 17475639.
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    28. Marsden MD, Zack JA. Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo. J Virol. 2007 Jun; 81(11):6146-50. PMID: 17392373.
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    29. McCrossan M, Marsden M, Carnie FW, Minnis S, Hansoti B, Anthony IC, Brettle RP, Bell JE, Simmonds P. An immune control model for viral replication in the CNS during presymptomatic HIV infection. Brain. 2006 Feb; 129(Pt 2):503-16. PMID: 16317019.
      View in: PubMed
    30. Morris A, Marsden M, Halcrow K, Hughes ES, Brettle RP, Bell JE, Simmonds P. Mosaic structure of the human immunodeficiency virus type 1 genome infecting lymphoid cells and the brain: evidence for frequent in vivo recombination events in the evolution of regional populations. J Virol. 1999 Oct; 73(10):8720-31. PMID: 10482626.
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    31. Adams MJ, Reichel MB, King IA, Marsden MD, Greenwood MD, Thirlwell H, Arnemann J, Buxton RS, Ali RR. Characterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigens. Biochem J. 1998 Jan 01; 329 ( Pt 1):165-74. PMID: 9405290.
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    32. Teresky AK, Marsden M, Kuff EL, Levine AJ. Morphological criteria for the in vitro differentiation of embryoid bodies produced by a transplantable teratoma of mice. J Cell Physiol. 1974 Oct; 84(2):319-32. PMID: 4474183.
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