Mazen Noureddin

Title(s)HS Associate Clinical Professor, Medicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
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    1. State-Level Hepatocellular Carcinoma Incidence and Association with Obesity and Physical Activity in the United States. Hepatology. 2021 Mar 17. Lee YT, Wang JJ, Luu M, Tseng HR, Rich NE, Lu SC, Nissen NN, Noureddin M, Singal AG, Yang JD. PMID: 33728665.
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    2. Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis. Expert Rev Clin Pharmacol. 2021 Mar 02; 1-8. PMID: 33612037.
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    3. Artificial Intelligence in NASH Histology: Human Teaches a Machine for the Machine to help Humans. Hepatology. 2021 Feb 26. PMID: 33638172.
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    4. Noninvasive Evaluation for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. Clin Ther. 2021 Feb 10. PMID: 33581876.
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    5. Therapeutic pipeline in nonalcoholic steatohepatitis. Nat Rev Gastroenterol Hepatol. 2021 Feb 10. PMID: 33568794.
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    6. Estrogen-Driven Growth of Focal Nodular Hyperplasia: Truth or Myth? ACG Case Rep J. 2021 Jan; 8(1):e00531. PMID: 33457441.
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    7. Role of Noninvasive Tests in Clinical Gastroenterology Practices to Identify Patients With Nonalcoholic Steatohepatitis at High Risk of Adverse Outcomes: Expert Panel Recommendations. Am J Gastroenterol. 2020 Dec 07. Younossi ZM, Noureddin M, Bernstein D, Kwo P, Russo M, Shiffman ML, Younes Z, Abdelmalek M. PMID: 33284184.
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    8. Sex differences in age at wait-list registration for liver transplantation with nonalcoholic steatohepatitis as primary indication. Clin Transplant. 2020 Dec 06; e14163. Steggerda JA, Noureddin N, Alkhouri N, Todo T, Dong Yang J, Kim IK, Noureddin M. PMID: 33280172.
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    9. Combination therapies including cilofexor and firsocostat for bridging fibrosis and cirrhosis due to NASH. Hepatology. 2020 Nov 10. Loomba R, Noureddin M, Kowdley KV, Kohli A, Sheikh A, Neff G, Bhandari BR, Gunn N, Caldwell SH, Goodman Z, Wapinski I, Resnick M, Beck AH, Ding D, Jia C, Chuang JC, Huss RS, Chung C, Subramanian GM, Myers RP, Patel K, Borg BB, Ghalib R, Kabler H, Poulos J, Younes Z, Elkhashab M, Hassanein T, Iyer R, Ruane P, Shiffman ML, Strasser S, Wong VW, Alkhouri N. PMID: 33169409.
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    10. Liver Injury Impaired 25-Hydroxylation of Vitamin D Suppresses Intestinal Paneth Cell defensins, leading to Gut Dysbiosis and Liver Fibrogenesis. Am J Physiol Gastrointest Liver Physiol. 2020 Oct 21. Wu P, Zhang R, Luo M, Zhang T, Pan L, Xu S, Pan L, Ren F, Ji C, Hu R, Noureddin M, Pandol SJ, Han YP. PMID: 33084400.
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    11. Increase in Alcoholic Hepatitis as an Etiology for Liver Transplantation in the United States: A 2004-2018 Analysis. Transplant Direct. 2020 Nov; 6(11):e612. Noureddin N, Yang JD, Alkhouri N, Noreen SM, Toll AE, Todo T, Ayoub W, Kuo A, Voidonikolas G, Kotler HG, Pelphrey MD, Durand BJ, Kosari K, Brennan TV, Kim I, Klein AS, Seki E, Nissen NN, Lu SC, Sundaram V, Noureddin M. PMID: 33134488.
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    12. Association of State Medicaid Expansion With Racial/Ethnic Disparities in Liver Transplant Wait-listing in the United States. JAMA Netw Open. 2020 10 01; 3(10):e2019869. Nephew LD, Mosesso K, Desai A, Ghabril M, Orman ES, Patidar KR, Kubal C, Noureddin M, Chalasani N. PMID: 33030554.
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    13. Acute on chronic liver failure from nonalcoholic fatty liver disease: a growing and aging cohort with rising mortality. Hepatology. 2020 Sep 22. Sundaram V, Jalan R, Shah P, Singal AK, Patel AA, Wu T, Noureddin M, Mahmud N, Wong RJ. PMID: 32961608.
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    14. Factors Associated With Detection and Survival of T1 Hepatocellular Carcinoma in the United States: National Cancer Database Analysis. J Natl Compr Canc Netw. 2020 09; 18(9):1210-1220. Yang JD, Luu M, Singal AG, Noureddin M, Kuo A, Ayoub WS, Sundaram V, Kotler H, Kim IK, Todo T, Voidonikolas G, Brennan TV, Kosari K, Klein AS, Hendifar A, Lu SC, Nissen NN, Gong J. PMID: 32886898.
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    15. Associations Between Reproductive and Hormone-Related Factors and Risk of Nonalcoholic Fatty Liver Disease in a Multiethnic Population. Clin Gastroenterol Hepatol. 2020 Aug 12. Wang J, Wu AH, Stanczyk FZ, Porcel J, Noureddin M, Terrault NA, Wilkens LR, Setiawan VW. PMID: 32801014.
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    16. Screening for Nonalcoholic Fatty Liver Disease in Persons with Type 2 Diabetes in the United States Is Cost-effective: A Comprehensive Cost-Utility Analysis. Gastroenterology. 2020 Nov; 159(5):1985-1987.e4. Noureddin M, Jones C, Alkhouri N, Gomez EV, Dieterich DT, Rinella ME. PMID: 32763241.
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    17. Driving Nonalcoholic Steatohepatitis Forward Using the FibroScan Aspartate Aminotransferase Score, But Obey the Traffic Lights. Hepatology. 2020 Aug 05. Noureddin N, Alkhouri N, Brown KA, Noureddin M. PMID: 32757393.
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    18. Clinical considerations in the management of non-alcoholic steatohepatitis cirrhosis pre- and post-transplant: A multi-system challenge. World J Gastroenterol. 2020 Jul 28; 26(28):4018-4035. Steggerda JA, Mahendraraj K, Todo T, Noureddin M. PMID: 32821068.
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    19. MR elastography-based liver fibrosis correlates with liver events in nonalcoholic fatty liver patients: A multicenter study. Liver Int. 2020 09; 40(9):2242-2251. Han MAT, Vipani A, Noureddin N, Ramirez K, Gornbein J, Saouaf R, Baniesh N, Cummings-John O, Okubote T, Setiawan VW, Rotman Y, Loomba R, Alkhouri N, Noureddin M. PMID: 32652744.
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    20. Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial. Hepatology. 2020 Jul; 72(1):58-71. Patel K, Harrison SA, Elkhashab M, Trotter JF, Herring R, Rojter SE, Kayali Z, Wong VW, Greenbloom S, Jayakumar S, Shiffman ML, Freilich B, Lawitz EJ, Gane EJ, Harting E, Xu J, Billin AN, Chung C, Djedjos CS, Subramanian GM, Myers RP, Middleton MS, Rinella M, Noureddin M. PMID: 32115759.
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    21. Clinical assessment for high-risk patients with non-alcoholic fatty liver disease in primary care and diabetology practices. Aliment Pharmacol Ther. 2020 08; 52(3):513-526. Younossi ZM, Corey KE, Alkhouri N, Noureddin M, Jacobson I, Lam B, Clement S, Basu R, Gordon SC, Ravendhra N, Puri P, Rinella M, Scudera P, Singal AK, Henry L. PMID: 32598051.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Dietary Protein, Fiber and Coffee Are Associated with Small Intestine Microbiome Composition and Diversity in Patients with Liver Cirrhosis. Nutrients. 2020 May 13; 12(5). Hussain SK, Dong TS, Agopian V, Pisegna JR, Durazo FA, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Ayoub WS, Lagishetty V, Elashoff D, Goodman MT, Jacobs JP. PMID: 32414035.
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    23. STELLAR 3 and STELLAR 4: Lessons from the fall of Icarus. J Hepatol. 2020 Jul; 73(1):9-11. Rinella ME, Noureddin M. PMID: 32360996.
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    24. Standardisation of diet and exercise in clinical trials of NAFLD-NASH: Recommendations from the Liver Forum. J Hepatol. 2020 Sep; 73(3):680-693. Glass O, Filozof C, Noureddin M, Berner-Hansen M, Schabel E, Omokaro SO, Schattenberg JM, Barradas K, Miller V, Francque S, Abdelmalek MF. PMID: 32353483.
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    25. Attribution of Nonalcoholic Steatohepatitis as an Etiology of Cirrhosis for Clinical Trials Eligibility: Recommendations From the Multi-stakeholder Liver Forum. Gastroenterology. 2020 Aug; 159(2):422-427.e1. Noureddin M, Chan JL, Barradas K, Dimick-Santos L, Schabel E, Omokaro SO, Anania FA, Myers RP, Miller V, Sanyal AJ, Chalasani N. PMID: 32353369.
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    26. Higher thresholds for the utilization of steatotic allografts in liver transplantation: Analysis from a U.S. national database. PLoS One. 2020; 15(4):e0230995. Steggerda JA, Bloom MB, Noureddin M, Brennan TV, Todo T, Nissen NN, Klein AS, Kim IK. PMID: 32240235.
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    27. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol. 2020 Feb 27; 12(2):46-63. Noureddin M, Sander-Struckmeier S, Mato JM. PMID: 32184941.
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    28. Diet Quality Association with Nonalcoholic Fatty Liver Disease by Cirrhosis Status: The Multiethnic Cohort. Curr Dev Nutr. 2020 Mar; 4(3):nzaa024. Park SY, Noureddin M, Boushey C, Wilkens LR, Setiawan VW. PMID: 32190810.
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    29. Diet Associations With Nonalcoholic Fatty Liver Disease in an Ethnically Diverse Population: The Multiethnic Cohort. Hepatology. 2020 Jun; 71(6):1940-1952. Noureddin M, Zelber-Sagi S, Wilkens LR, Porcel J, Boushey CJ, Le Marchand L, Rosen HR, Setiawan VW. PMID: 31553803.
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    30. Noninvasive Testing Using Magnetic Resonance Imaging Techniques as Outcomes in Nonalcoholic Steatohepatitis Clinical Trials: How Full Is the Glass? Hepatol Commun. 2020 Feb; 4(2):141-144. Noureddin N, Schattenberg JM, Alkhouri N, Noureddin M. PMID: 32025600.
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    31. Vitamin D signaling maintains intestinal innate immunity and gut microbiota: potential intervention for metabolic syndrome and NAFLD. Am J Physiol Gastrointest Liver Physiol. 2020 03 01; 318(3):G542-G553. Zeng Y, Luo M, Pan L, Chen Y, Guo S, Luo D, Zhu L, Liu Y, Pan L, Xu S, Zhang R, Zhang C, Wu P, Ge L, Noureddin M, Pandol SJ, Han YP. PMID: 31984787.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)? Expert Opin Investig Drugs. 2020 Feb; 29(2):197-204. Ritchie M, Hanouneh IA, Noureddin M, Rolph T, Alkhouri N. PMID: 31948295.
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    33. Drug discovery and treatment paradigms in nonalcoholic steatohepatitis. Endocrinol Diabetes Metab. 2020 Oct; 3(4):e00105. Noureddin M, Muthiah MD, Sanyal AJ. PMID: 33102791.
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    34. Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension. Gastroenterology. 2020 04; 158(5):1334-1345.e5. Chalasani N, Abdelmalek MF, Garcia-Tsao G, Vuppalanchi R, Alkhouri N, Rinella M, Noureddin M, Pyko M, Shiffman M, Sanyal A, Allgood A, Shlevin H, Horton R, Zomer E, Irish W, Goodman Z, Harrison SA, Traber PG. PMID: 31812510.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    35. Characterization of patients with both alcoholic and nonalcoholic fatty liver disease in a large United States cohort. World J Hepatol. 2019 Oct 27; 11(10):710-718. Khoudari G, Singh A, Noureddin M, Fritze D, Lopez R, Asaad I, Lawitz E, Poordad F, Kowdley KV, Alkhouri N. PMID: 31749901.
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    36. Fibrosis Changes in the Placebo Arm of NASH Clinical Trials. Clin Gastroenterol Hepatol. 2019 10; 17(11):2387. Altayar O, Noureddin N, Thanda Han MA, Murad MH, Noureddin M. PMID: 31543242.
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    37. GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH). Expert Opin Investig Drugs. 2020 Feb; 29(2):135-141. Alkhouri N, Lawitz E, Noureddin M, DeFronzo R, Shulman GI. PMID: 31519114.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Screening for Nonalcoholic Fatty Liver Disease in the Primary Care Clinic. Gastroenterol Hepatol (N Y). 2019 Jul; 15(7):357-365. Pandyarajan V, Gish RG, Alkhouri N, Noureddin M. PMID: 31391806.
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    39. Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. World J Gastroenterol. 2019 Jun 28; 25(24):3009-3020. Mato JM, Alonso C, Noureddin M, Lu SC. PMID: 31293337.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Sci Transl Med. 2019 06 12; 11(496). Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E. PMID: 31189722.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Awareness of Nonalcoholic Fatty Liver Disease Is Increasing but Remains Very Low in a Representative US Cohort. Dig Dis Sci. 2020 04; 65(4):978-986. Singh A, Dhaliwal AS, Singh S, Kumar A, Lopez R, Gupta M, Noureddin M, Carey W, McCullough A, Alkhouri N. PMID: 31187324.
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    42. Looking Into the Crystal Ball: Predicting the Future Challenges of Fibrotic NASH Treatment. Hepatol Commun. 2019 May; 3(5):605-613. Alkhouri N, Lawitz E, Noureddin M. PMID: 31061949.
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    43. Ga12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602. Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG. PMID: 30300140.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    44. Pathogenesis of NASH: The Impact of Multiple Pathways. Curr Hepatol Rep. 2018 Dec; 17(4):350-360. Noureddin M, Sanyal AJ. PMID: 31380156.
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    45. Liver Transplantation for Severe Alcoholic Hepatitis: Report of a Single Center Pilot Program. Transplant Proc. 2018 Dec; 50(10):3527-3532. Sundaram V, Wu T, Klein AS, Noureddin M, Kim IK, Todo T, Ayoub WS, Galloway C, Christianson AL, Nissen NN. PMID: 30577231.
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    46. Editorial: role of leucine-metformin-sildenafil combination in the treatment of nonalcoholic fatty liver disease (NAFLD). Aliment Pharmacol Ther. 2018 08; 48(3):378-379. Noureddin M, Loomba R. PMID: 29998503.
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    47. Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study. Hepatol Res. 2018 Dec; 48(13):1108-1117. Jacobs JP, Dong TS, Agopian V, Lagishetty V, Sundaram V, Noureddin M, Ayoub WS, Durazo F, Benhammou J, Enayati P, Elashoff D, Goodman MT, Pisegna J, Hussain S. PMID: 29923681.
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    48. GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 11; 155(5):1463-1473.e6. Loomba R, Kayali Z, Noureddin M, Ruane P, Lawitz EJ, Bennett M, Wang L, Harting E, Tarrant JM, McColgan BJ, Chung C, Ray AS, Subramanian GM, Myers RP, Middleton MS, Lai M, Charlton M, Harrison SA. PMID: 30059671.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    49. Rates of and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2019 03; 17(4):616-629.e26. Han MAT, Altayar O, Hamdeh S, Takyar V, Rotman Y, Etzion O, Lefebvre E, Safadi R, Ratziu V, Prokop LJ, Murad MH, Noureddin M. PMID: 29913275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances. Am J Gastroenterol. 2018 11; 113(11):1649-1659. Noureddin M, Vipani A, Bresee C, Todo T, Kim IK, Alkhouri N, Setiawan VW, Tran T, Ayoub WS, Lu SC, Klein AS, Sundaram V, Nissen NN. PMID: 29880964.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    51. Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer. Gastroenterology. 2018 08; 155(2):557-571.e14. Liu T, Yang H, Fan W, Tu J, Li TWH, Wang J, Shen H, Yang J, Xiong T, Steggerda J, Liu Z, Noureddin M, Maldonado SS, Annamalai A, Seki E, Mato JM, Lu SC. PMID: 29733835.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    52. Metabolomic-based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts. Hepatol Commun. 2018 Jul; 2(7):807-820. Mayo R, Crespo J, Martínez-Arranz I, Banales JM, Arias M, Mincholé I, Aller de la Fuente R, Jimenez-Agüero R, Alonso C, de Luis DA, Vitek L, Stritesky J, Caballería J, Romero-Gómez M, Martín-Duce A, Mugüerza Huguet JM, Busteros-Moraza JI, Idowu MO, Castro A, Martínez-Chantar ML, Ortiz P, Bruha R, Lu SC, Bedossa P, Noureddin M, Sanyal AJ, Mato JM. PMID: 30027139.
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    53. Class III obesity is a risk factor for the development of acute-on-chronic liver failure in patients with decompensated cirrhosis. J Hepatol. 2018 09; 69(3):617-625. Sundaram V, Jalan R, Ahn JC, Charlton MR, Goldberg DS, Karvellas CJ, Noureddin M, Wong RJ. PMID: 29709681.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    54. Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals. World J Gastroenterol. 2018 Mar 21; 24(11):1269-1277. Noureddin M, Wong MM, Todo T, Lu SC, Sanyal AJ, Mena EA. PMID: 29568207.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    55. Insulin signaling as a potential natural killer cell checkpoint in fatty liver disease. Hepatol Commun. 2018 03; 2(3):285-298. Amer J, Salhab A, Noureddin M, Doron S, Abu-Tair L, Ghantous R, Mahamid M, Safadi R. PMID: 29507903.
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    56. Role of Aramchol in steatohepatitis and fibrosis in mice. Hepatol Commun. 2017 Nov; 1(9):911-927. Iruarrizaga-Lejarreta M, Varela-Rey M, Fernández-Ramos D, Martínez-Arranz I, Delgado TC, Simon J, Juan VG, delaCruz-Villar L, Azkargorta M, Lavin JL, Mayo R, Van Liempd SM, Aurrekoetxea I, Buqué X, Cave DD, Peña A, Rodríguez-Cuesta J, Aransay AM, Elortza F, Falcón-Pérez JM, Aspichueta P, Hayardeny L, Noureddin M, Sanyal AJ, Alonso C, Anguita J, Martínez-Chantar ML, Lu SC, Mato JM. PMID: 29159325.
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    57. The role of bariatric surgery in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Expert Rev Gastroenterol Hepatol. 2017 Sep; 11(9):797-811. Shouhed D, Steggerda J, Burch M, Noureddin M. PMID: 28712339.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    58. Coffee Drinking and Alcoholic and Nonalcoholic Fatty Liver Diseases and Viral Hepatitis in the Multiethnic Cohort. Clin Gastroenterol Hepatol. 2017 08; 15(8):1305-1307. Setiawan VW, Porcel J, Wei P, Stram DO, Noureddin N, Lu SC, Le Marchand L, Noureddin M. PMID: 28300689.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    59. Magnetic resonance imaging and transient elastography in the management of Nonalcoholic Fatty Liver Disease (NAFLD). Expert Rev Clin Pharmacol. 2017 Apr; 10(4):379-390. Han MA, Saouaf R, Ayoub W, Todo T, Mena E, Noureddin M. PMID: 28277807.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    60. Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells. Hepatology. 2017 04; 65(4):1249-1266. Fan W, Yang H, Liu T, Wang J, Li TW, Mavila N, Tang Y, Yang J, Peng H, Tu J, Annamalai A, Noureddin M, Krishnan A, Gores GJ, Martínez-Chantar ML, Mato JM, Lu SC. PMID: 27981602.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    61. Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis. Gastroenterology. 2017 05; 152(6):1449-1461.e7. Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavín Trueba JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gómez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM. PMID: 28132890.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    62. Predictors of Mortality in the Critically Ill Cirrhotic Patient: Is the Model for End-Stage Liver Disease Enough? J Am Coll Surg. 2017 Mar; 224(3):276-282. Annamalai A, Harada MY, Chen M, Tran T, Ko A, Ley EJ, Nuno M, Klein A, Nissen N, Noureddin M. PMID: 27887981.
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    63. Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis. Aliment Pharmacol Ther. 2016 12; 44(11-12):1183-1198. Harrison SA, Marri SR, Chalasani N, Kohli R, Aronstein W, Thompson GA, Irish W, Miles MV, Xanthakos SA, Lawitz E, Noureddin M, Schiano TD, Siddiqui M, Sanyal A, Neuschwander-Tetri BA, Traber PG. PMID: 27778367.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    64. Promising therapies for treatment of nonalcoholic steatohepatitis. Expert Opin Emerg Drugs. 2016 Sep; 21(3):343-57. Noureddin M, Zhang A, Loomba R. PMID: 27501374.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    65. Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort. Hepatology. 2016 12; 64(6):1969-1977. Setiawan VW, Stram DO, Porcel J, Lu SC, Le Marchand L, Noureddin M. PMID: 27301913.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    66. Review article: emerging anti-fibrotic therapies in the treatment of non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2016 06; 43(11):1109-23. Noureddin M, Anstee QM, Loomba R. PMID: 27061197.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    67. The Significance of Autoantibody Changes Over Time in Primary Biliary Cirrhosis. Am J Clin Pathol. 2015 Oct; 144(4):601-6. Tana MM, Shums Z, Milo J, Norman GL, Leung PS, Gershwin ME, Noureddin M, Kleiner DE, Zhao X, Heller T, Hoofnagle JH. PMID: 26386081.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    68. Sofosbuvir and Simeprevir Therapy for Recurrent Hepatitis C Infection After Liver Transplantation. Transplant Direct. 2015 Jul; 1(6):e21. Khemichian S, Lee B, Kahn J, Noureddin M, Kim B, Harper T, Esmailian Y, Fong TL. PMID: 27500223.
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    69. Hepatic expression levels of interferons and interferon-stimulated genes in patients with chronic hepatitis C: A phenotype-genotype correlation study. Genes Immun. 2015 Jul-Aug; 16(5):321-9. Noureddin M, Rotman Y, Zhang F, Park H, Rehermann B, Thomas E, Liang TJ. PMID: 26020282.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    70. Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine. Exp Biol Med (Maywood). 2015 Jun; 240(6):809-20. Noureddin M, Mato JM, Lu SC. PMID: 25873078.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    71. MRI, CT scan, and ultrasound in the diagnosis of nonalcoholic fatty liver disease. J Clin Gastroenterol. 2015 Apr; 49(4):351-2. Noureddin M, Khoyilar C, Palmer SL. PMID: 25551206.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    72. Nonalcoholic Fatty liver disease, diabetes, obesity, and hepatocellular carcinoma. Clin Liver Dis. 2015 May; 19(2):361-79. Noureddin M, Rinella ME. PMID: 25921668.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    73. Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Hepatology. 2015 Apr; 61(4):1239-50. Loomba R, Sirlin CB, Ang B, Bettencourt R, Jain R, Salotti J, Soaft L, Hooker J, Kono Y, Bhatt A, Hernandez L, Nguyen P, Noureddin M, Haufe W, Hooker C, Yin M, Ehman R, Lin GY, Valasek MA, Brenner DA, Richards L, . PMID: 25482832.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    74. Ribavirin improves the IFN-? response of natural killer cells to IFN-based therapy of hepatitis C virus infection. Hepatology. 2014 Oct; 60(4):1160-9. Werner JM, Serti E, Chepa-Lotrea X, Stoltzfus J, Ahlenstiel G, Noureddin M, Feld JJ, Liang TJ, Rotman Y, Rehermann B. PMID: 24700342.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    75. Reply: To PMID 23703931. Hepatology. 2014 Apr; 59(4):1651. Noureddin M, Wright EC, Ghany MG. PMID: 23959972.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    76. Hepatitis delta: epidemiology, diagnosis and management 36 years after discovery. Curr Gastroenterol Rep. 2014 Jan; 16(1):365. Noureddin M, Gish R. PMID: 24293018.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    77. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology. 2013 Dec; 58(6):1930-40. Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. PMID: 23696515.
      View in: PubMed   Mentions: 116     Fields:    Translation:Humans
    78. Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients. Hepatology. 2013 Nov; 58(5):1644-54. Noureddin M, Yates KP, Vaughn IA, Neuschwander-Tetri BA, Sanyal AJ, McCullough A, Merriman R, Hameed B, Doo E, Kleiner DE, Behling C, Loomba R, . PMID: 23686698.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    79. Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis. Hepatology. 2013 Nov; 58(5):1548-57. Noureddin M, Wright EC, Alter HJ, Clark S, Thomas E, Chen R, Zhao X, Conry-Cantilena C, Kleiner DE, Liang TJ, Ghany MG. PMID: 23703931.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    80. Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype. J Hepatol. 2013 Nov; 59(5):957-63. Han H, Noureddin M, Witthaus M, Park YJ, Hoofnagle JH, Liang TJ, Rotman Y. PMID: 23850879.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    81. Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C. Gut. 2014 Jan; 63(1):161-9. Rotman Y, Noureddin M, Feld JJ, Guedj J, Witthaus M, Han H, Park YJ, Park SH, Heller T, Ghany MG, Doo E, Koh C, Abdalla A, Gara N, Sarkar S, Thomas E, Ahlenstiel G, Edlich B, Titerence R, Hogdal L, Rehermann B, Dahari H, Perelson AS, Hoofnagle JH, Liang TJ. PMID: 23396509.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    82. Nonalcoholic fatty liver disease: Indications for liver biopsy and noninvasive biomarkers. Clin Liver Dis (Hoboken). 2012 Sep; 1(4):104-107. Noureddin M, Loomba R. PMID: 31186861.
      View in: PubMed   Mentions:
    83. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology. 2012 Apr; 142(4):978-88. Thomas E, Gonzalez VD, Li Q, Modi AA, Chen W, Noureddin M, Rotman Y, Liang TJ. PMID: 22248663.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    84. Early changes in interferon signaling define natural killer cell response and refractoriness to interferon-based therapy of hepatitis C patients. Hepatology. 2012 Jan; 55(1):39-48. Edlich B, Ahlenstiel G, Zabaleta Azpiroz A, Stoltzfus J, Noureddin M, Serti E, Feld JJ, Liang TJ, Rotman Y, Rehermann B. PMID: 21898483.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCellsCTClinical Trials
    85. Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C. Gastroenterology. 2011 Oct; 141(4):1231-9, 1239.e1-2. Ahlenstiel G, Edlich B, Hogdal LJ, Rotman Y, Noureddin M, Feld JJ, Holz LE, Titerence RH, Liang TJ, Rehermann B. PMID: 21741920.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    86. Editorial: Treatment of patients with HCV-related cirrhosis with peginterferon and ribavirin: Swinging the pendulum toward treatment. Am J Gastroenterol. 2010 Oct; 105(10):2174-6. Noureddin M, Ghany MG. PMID: 20927065.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    87. To resect or not to resect? That is the question. Telangiectatic adenoma. Gut. 2011 Sep; 60(9):1177, 1235. Noureddin M, Kleiner DE, Gharib AM, Bratslavsky G, Heller T. PMID: 20965874.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    88. Pharmacokinetics and pharmacodynamics of peginterferon and ribavirin: implications for clinical efficacy in the treatment of chronic hepatitis C. Gastroenterol Clin North Am. 2010 Sep; 39(3):649-58. Noureddin M, Ghany MG. PMID: 20951922.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    89. Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice. Lab Invest. 2008 Oct; 88(10):1121-9. Ko K, Yang H, Noureddin M, Iglesia-Ara A, Xia M, Wagner C, Luka Z, Mato JM, Lu SC. PMID: 18695670.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    90. Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells. J Cell Physiol. 2007 Mar; 210(3):766-73. Yang H, Magilnick N, Noureddin M, Mato JM, Lu SC. PMID: 17154373.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    91. Platelet FcgammaRIIA receptor surface expression is increased in patients with ESRD and is associated with atherosclerotic cardiovascular events. Am J Kidney Dis. 2007 Jan; 49(1):127-34. El-Shahawy M, Noureddin M, Abdullah H, Mack WJ, Calverley DC. PMID: 17185153.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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