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The Effect of Race/Ethnicity and MED12 Mutation on the Expression of Long Non-Coding RNAs in Uterine Leiomyoma and Myometrium. Int J Mol Sci. 2024 Jan 21; 25(2).
Chuang TD, Ton N, Rysling S, Boos D, Khorram O. PMID: 38279317; PMCID: PMC10816284.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Therapeutic effects of in vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study. Fertil Steril. 2024 Apr; 121(4):669-678.
Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Khorram O. PMID: 38072367; PMCID: PMC10978289.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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The Influence of Race/Ethnicity on the Transcriptomic Landscape of Uterine Fibroids. Int J Mol Sci. 2023 Aug 30; 24(17).
Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Gao J, McSwiggin H, Yan W, Khorram O. PMID: 37686244; PMCID: PMC10487975.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Therapeutic Effects of Long-Term Administration of Tranilast in an Animal Model for the Treatment of Fibroids. Int J Mol Sci. 2023 Jun 21; 24(13).
Chuang TD, Munoz L, Quintanilla D, Boos D, Khorram O. PMID: 37445642; PMCID: PMC10341593.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Differential Expression of MED12-Associated Coding RNA Transcripts in Uterine Leiomyomas. Int J Mol Sci. 2023 Feb 13; 24(4).
Chuang TD, Gao J, Quintanilla D, McSwiggin H, Boos D, Yan W, Khorram O. PMID: 36835153; PMCID: PMC9960582.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Differential Expression of Super-Enhancer-Associated Long Non-coding RNAs in Uterine Leiomyomas. Reprod Sci. 2022 10; 29(10):2960-2976.
Chuang TD, Quintanilla D, Boos D, Khorram O. PMID: 35641855; PMCID: PMC9537225.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Further characterization of tryptophan metabolism and its dysregulation in fibroids. F S Sci. 2022 11; 3(4):392-400.
Chuang TD, Quintanilla D, Boos D, Khorram O. PMID: 35715314; PMCID: PMC9617805.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
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Long Noncoding RNA MIAT Modulates the Extracellular Matrix Deposition in Leiomyomas by Sponging MiR-29 Family. Endocrinology. 2021 11 01; 162(11).
Chuang TD, Quintanilla D, Boos D, Khorram O. PMID: 34491311; PMCID: PMC8459448.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Fibroid stiffness: a cellular modulator of progesterone receptor signaling. Fertil Steril. 2021 07; 116(1):91.
Khorram O, Chuang TD. PMID: 34148597.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Tryptophan catabolism is dysregulated in leiomyomas. Fertil Steril. 2021 10; 116(4):1160-1171.
Chuang TD, Quintanilla D, Boos D, Khorram O. PMID: 34116832; PMCID: PMC8787760.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Functional role of the long noncoding RNA X-inactive specific transcript in leiomyoma pathogenesis. Fertil Steril. 2021 01; 115(1):238-247.
Chuang TD, Rehan A, Khorram O. PMID: 33070965; PMCID: PMC7796933.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Mechanism underlying increased cardiac extracellular matrix deposition in perinatal nicotine-exposed offspring. Am J Physiol Heart Circ Physiol. 2020 09 01; 319(3):H651-H660.
Chuang TD, Ansari A, Yu C, Sakurai R, Harb A, Liu J, Khorram O, Rehan VK. PMID: 32795172; PMCID: PMC7509277.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells. Fertil Steril. 2020 06; 113(6):1308-1318.
Chuang TD, Rehan A, Khorram O. PMID: 32199621; PMCID: PMC7269851.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Cross-talk between miR-29c and transforming growth factor-β3 is mediated by an epigenetic mechanism in leiomyoma. Fertil Steril. 2019 12; 112(6):1180-1189.
Chuang TD, Khorram O. PMID: 31843095; PMCID: PMC6924575.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Role of miR-29 in mediating offspring lung phenotype in a rodent model of intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol. 2018 11 01; 315(5):R1017-R1026.
Chuang TD, Sakurai R, Gong M, Khorram O, Rehan VK. PMID: 30088984; PMCID: PMC6295497.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma. Fertil Steril. 2018 05; 109(5):919-929.
Chuang TD, Xie Y, Yan W, Khorram O. PMID: 29778390; PMCID: PMC6445395.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
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Regulation of Cell Cycle Regulatory Proteins by MicroRNAs in Uterine Leiomyoma. Reprod Sci. 2019 02; 26(2):250-258.
Chuang TD, Khorram O. PMID: 29642801; PMCID: PMC6728566.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms. Life Sci. 2017 Oct 01; 186:87-91.
Chuang TD, Khorram O. PMID: 28801263.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Expression Profiling of lncRNAs, miRNAs, and mRNAs and Their Differential Expression in Leiomyoma Using Next-Generation RNA Sequencing. Reprod Sci. 2018 02; 25(2):246-255.
Chuang TD, Khorram O. PMID: 28587571.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells. Reprod Sci. 2017 09; 24(9):1253-1263.
Chuang TD, Khorram O. PMID: 28114878.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma. Fertil Steril. 2016 Jan; 105(1):236-45.e1.
Chuang TD, Khorram O. PMID: 26453978.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids. Am J Physiol Cell Physiol. 2015 Jul 15; 309(2):C117-25.
Chuang TD, Pearce WJ, Khorram O. PMID: 26017148; PMCID: PMC4504943.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c. J Dev Orig Health Dis. 2015 Aug; 6(4):342-9.
Khorram O, Chuang TD, Pearce WJ. PMID: 26008599; PMCID: PMC5142447.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
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Maternal undernutrition induces premature reproductive senescence in adult female rat offspring. Fertil Steril. 2015 Jan; 103(1):291-8.e2.
Khorram O, Keen-Rinehart E, Chuang TD, Ross MG, Desai M. PMID: 25439841; PMCID: PMC4282592.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
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The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line. Reprod Sci. 2015 May; 22(5):563-71.
Chuang TD, Ho M, Khorram O. PMID: 25305131.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Metyrapone alleviates deleterious effects of maternal food restriction on lung development and growth of rat offspring. Reprod Sci. 2015 Feb; 22(2):207-22.
Paek DS, Sakurai R, Saraswat A, Li Y, Khorram O, Torday JS, Rehan VK. PMID: 24916330; PMCID: PMC4287596.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial. Menopause. 2014 Jun; 21(6):612-23.
Huang G, Basaria S, Travison TG, Ho MH, Davda M, Mazer NA, Miciek R, Knapp PE, Zhang A, Collins L, Ursino M, Appleman E, Dzekov C, Stroh H, Ouellette M, Rundell T, Baby M, Bhatia NN, Khorram O, Friedman T, Storer TW, Bhasin S. PMID: 24281237; PMCID: PMC4701202.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
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miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis. PLoS One. 2014; 9(4):e95370.
Chuang TD, Khorram O. PMID: 24755559; PMCID: PMC3995706.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone. Am J Physiol Regul Integr Comp Physiol. 2014 Mar 15; 306(6):R401-10.
Durrant LM, Khorram O, Buchholz JN, Pearce WJ. PMID: 24477541; PMCID: PMC3949108.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
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Excess maternal glucocorticoids in response to in utero undernutrition inhibit offspring angiogenesis. Reprod Sci. 2014 May; 21(5):601-11.
Khorram O, Ghazi R, Chuang TD, Han G, Naghi J, Ni Y, Pearce WJ. PMID: 24155066; PMCID: PMC3984487.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Metyrapone blocks maternal food restriction-induced changes in female rat offspring lung development. Reprod Sci. 2014 Apr; 21(4):517-25.
Rehan VK, Li Y, Corral J, Saraswat A, Husain S, Dhar A, Sakurai R, Khorram O, Torday JS. PMID: 24023031; PMCID: PMC3960838.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
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Maturation and differentiation of the fetal vasculature. Clin Obstet Gynecol. 2013 Sep; 56(3):537-48.
Pearce WJ, Khorram O. PMID: 23820122; PMCID: PMC3914998.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Chronic hypoxia and VEGF differentially modulate abundance and organization of myosin heavy chain isoforms in fetal and adult ovine arteries. Am J Physiol Cell Physiol. 2012 Nov 15; 303(10):C1090-103.
Hubbell MC, Semotiuk AJ, Thorpe RB, Adeoye OO, Butler SM, Williams JM, Khorram O, Pearce WJ. PMID: 22992677; PMCID: PMC3492831.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
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Altered endometrial expression of endothelial nitric oxide synthase in women with unexplained recurrent miscarriage and infertility. Reprod Biomed Online. 2012 Oct; 25(4):408-14.
Najafi T, Novin MG, Ghazi R, Khorram O. PMID: 22877939; PMCID: PMC3523691.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Contributions of VEGF to age-dependent transmural gradients in contractile protein expression in ovine carotid arteries. Am J Physiol Cell Physiol. 2011 Sep; 301(3):C653-66.
Butler SM, Abrassart JM, Hubbell MC, Adeoye O, Semotiuk A, Williams JM, Mata-Greenwood E, Khorram O, Pearce WJ. PMID: 21653901; PMCID: PMC3174571.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
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Maternal undernutrition programs offspring adrenal expression of steroidogenic enzymes. Reprod Sci. 2011 Oct; 18(10):931-40.
Khorram NM, Magee TR, Wang C, Desai M, Ross M, Khorram O. PMID: 21566243; PMCID: PMC3343113.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Effect of maternal undernutrition on vascular expression of micro and messenger RNA in newborn and aging offspring. Am J Physiol Regul Integr Comp Physiol. 2010 May; 298(5):R1366-74.
Khorram O, Han G, Bagherpour R, Magee TR, Desai M, Ross MG, Chaudhri AA, Toloubeydokhti T, Pearce WJ. PMID: 20200130; PMCID: PMC2867511.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
-
Cigarette smoke inhibits endometrial epithelial cell proliferation through a nitric oxide-mediated pathway. Fertil Steril. 2010 Jan; 93(1):257-63.
Khorram O, Han G, Magee T. PMID: 19022425.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Influence of progesterone on endometrial nitric oxide synthase expression. Fertil Steril. 2009 May; 91(5 Suppl):2157-62.
Khorram O, Han G. PMID: 18710710; PMCID: PMC2759679.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Down-regulation of transcription factor peroxisome proliferator-activated receptor in programmed hepatic lipid dysregulation and inflammation in intrauterine growth-restricted offspring. Am J Obstet Gynecol. 2008 Sep; 199(3):271.e1-5.
Magee TR, Han G, Cherian B, Khorram O, Ross MG, Desai M. PMID: 18667178; PMCID: PMC2597035.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Maternal undernutrition inhibits angiogenesis in the offspring: a potential mechanism of programmed hypertension. Am J Physiol Regul Integr Comp Physiol. 2007 Aug; 293(2):R745-53.
Khorram O, Khorram N, Momeni M, Han G, Halem J, Desai M, Ross MG. PMID: 17507434.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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In utero undernutrition in rats induces increased vascular smooth muscle content in the offspring. Am J Obstet Gynecol. 2007 May; 196(5):486.e1-8.
Khorram O, Momeni M, Ferrini M, Desai M, Ross MG. PMID: 17466715.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Gestational programming of offspring obesity: a potential contributor to Alzheimer's disease. Curr Alzheimer Res. 2007 Apr; 4(2):213-7.
Ross MG, Desai M, Khorram O, McKnight RA, Lane RH, Torday J. PMID: 17430249.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Nutrient restriction in utero induces remodeling of the vascular extracellular matrix in rat offspring. Reprod Sci. 2007 Jan; 14(1):73-80.
Khorram O, Momeni M, Desai M, Ross MG. PMID: 17636219.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Expression of endometrial glycogen synthase kinase-3beta protein throughout the menstrual cycle and its regulation by progesterone. Mol Hum Reprod. 2006 Sep; 12(9):543-9.
Salameh W, Helliwell JP, Han G, McPhaul L, Khorram O. PMID: 16882987.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Two weeks of metformin improves clomiphene citrate-induced ovulation and metabolic profiles in women with polycystic ovary syndrome. Fertil Steril. 2006 May; 85(5):1448-51.
Khorram O, Helliwell JP, Katz S, Bonpane CM, Jaramillo L. PMID: 16579997.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
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Human seminal plasma nitric oxide: correlation with sperm morphology and testosterone. Med Sci Monit. 2006 Mar; 12(3):CR103-6.
Huang I, Jones J, Khorram O. PMID: 16501419.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Regulation of nitric oxide synthase isoforms by estrogen in the human endometrium. Fertil Steril. 2005 Oct; 84 Suppl 2:1220-7.
Han G, Magee T, Khorram O. PMID: 16210014.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Abnormal aminotransferase activity in women with polycystic ovary syndrome. Fertil Steril. 2005 Feb; 83(2):494-7.
Schwimmer JB, Khorram O, Chiu V, Schwimmer WB. PMID: 15705403.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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Identification and characterization of a novel luciferase-like protein in the human female reproductive tract. J Clin Endocrinol Metab. 2004 Nov; 89(11):5837-46.
Khorram O, Garthwaite M, Johnson MS, Denessiouk KA, Han G, Guo T, McPhaul LW, Magee TR, Westerman B, Golos TG. PMID: 15531550.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Physiologic role of nitric oxide and nitric oxide synthase in female lower urinary tract. Curr Opin Obstet Gynecol. 2004 Oct; 16(5):423-9.
Ho MH, Bhatia NN, Khorram O. PMID: 15353953.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Expression of aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA expression in human spermatozoa. Med Sci Monit. 2004 May; 10(5):BR135-8.
Khorram O, Garthwaite M, Jones J, Golos T. PMID: 15114261.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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An unusual case of ovarian resistance syndrome. Obstet Gynecol. 2003 May; 101(5 Pt 2):1078-82.
Katz S, Marshall J, Khorram O. PMID: 12738108.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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The influence of sex hormones on circulating nitric oxide (NOx) levels in rhesus monkeys (Macaca Mulatta). Med Sci Monit. 2002 Dec; 8(12):BR489-95.
Khorram O, Colman RJ, Kemnitz JW, Magness RR, Zhang J, Yao Z, Keller ET. PMID: 12503026.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
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Recalculation of gestational sac losses in multifetal pregnancy. Am J Obstet Gynecol. 2002 Sep; 187(3):820-1; author reply 821.
Ross MG, Khorram O. PMID: 12237672.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Nitric oxide and its role in blastocyst implantation. Rev Endocr Metab Disord. 2002 May; 3(2):145-9.
Khorram O. PMID: 12007291.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Uterine and ovarian aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA expression in benign and malignant gynaecological conditions. Mol Hum Reprod. 2002 Jan; 8(1):75-80.
Khorram O, Garthwaite M, Golos T. PMID: 11756572.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
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Potential therapeutic effects of prescribed and over-the-counter androgens in women. Clin Obstet Gynecol. 2001 Dec; 44(4):880-92.
Khorram O. PMID: 11600868.
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PubMed Mentions: Fields:
Translation:
Humans
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Use of growth hormone and growth hormone secretagogues in aging: help or harm. Clin Obstet Gynecol. 2001 Dec; 44(4):893-901.
Khorram O. PMID: 11600869.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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The influence of aging and sex hormones on expression of growth hormone-releasing hormone in the human immune system. J Clin Endocrinol Metab. 2001 Jul; 86(7):3157-61.
Khorram O, Garthwaite M, Golos T. PMID: 11443181.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Reproductive technologies for male infertility. J Clin Endocrinol Metab. 2001 Jun; 86(6):2373-9.
Khorram O, Patrizio P, Wang C, Swerdloff R. PMID: 11397826.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Human uterine and ovarian expression of growth hormone-releasing hormone messenger RNA in benign and malignant gynecologic conditions. Fertil Steril. 2001 Jan; 75(1):174-9.
Khorram O, Garthwaite M, Grosen E, Golos T. PMID: 11163834.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Transfer of nonassisted hatched and hatching human blastocysts after in vitro fertilization. Fertil Steril. 2000 Jul; 74(1):163-5.
Khorram O, Shapiro SS, Jones JM. PMID: 10899515.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Endometrial and myometrial expression of nitric oxide synthase isoforms in pre- and postmenopausal women. J Clin Endocrinol Metab. 1999 Jun; 84(6):2226-32.
Khorram O, Garthwaite M, Magness RR. PMID: 10372735.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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DHEA: a hormone with multiple effects. Curr Opin Obstet Gynecol. 1996 Oct; 8(5):351-4.
Khorram O. PMID: 8941432.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Interleukin-8 concentrations are elevated in peritoneal fluid of women with endometriosis. Fertil Steril. 1995 Apr; 63(4):929-32.
Ryan IP, Tseng JF, Schriock ED, Khorram O, Landers DV, Taylor RN. PMID: 7890085.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis. Am J Obstet Gynecol. 1993 Dec; 169(6):1545-9.
Khorram O, Taylor RN, Ryan IP, Schall TJ, Landers DV. PMID: 7505529.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Age-, sex-, and gonadal steroid-related changes in immunoreactive substance P in the rat anterior pituitary gland. Endocrinology. 1985 Oct; 117(4):1368-73.
DePalatis LR, Khorram O, McCann SM. PMID: 2411526.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
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Hypothalamic control of prolactin secretion during the perinatal period in the rat. Endocrinology. 1984 Nov; 115(5):1698-704.
Khorram O, Depalatis LR, McCann SM. PMID: 6436004.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
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Development of hypothalamic control of growth hormone secretion in the rat. Endocrinology. 1983 Aug; 113(2):720-8.
Khorram O, DePalatis LR, McCann SM. PMID: 6135598.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals