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Peter M Bowers

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
Phone3102061635
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020 01 02; 130(1):315-328. Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP. PMID: 31613796.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies. Methods Mol Biol. 2018; 1827:479-489. Bowers PM, Boyle WJ, Damoiseaux R. PMID: 30196512.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. A Randomized, Open-Label, Multicenter, Phase III Study of Epoetin Alfa Versus Best Standard of Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy. J Clin Oncol. 2016 04 10; 34(11):1197-207. Leyland-Jones B, Bondarenko I, Nemsadze G, Smirnov V, Litvin I, Kokhreidze I, Abshilava L, Janjalia M, Li R, Lakshmaiah KC, Samkharadze B, Tarasova O, Mohapatra RK, Sparyk Y, Polenkov S, Vladimirov V, Xiu L, Zhu E, Kimelblatt B, Deprince K, Safonov I, Bowers P, Vercammen E. PMID: 26858335.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    4. Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J Biol Chem. 2014 Nov 28; 289(48):33557-67. Bowers PM, Verdino P, Wang Z, da Silva Correia J, Chhoa M, Macondray G, Do M, Neben TY, Horlick RA, Stanfield RL, Wilson IA, King DJ. PMID: 25320089.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Mammalian cell display and somatic hypermutation in vitro for human antibody discovery. Curr Drug Discov Technol. 2014 Mar; 11(1):56-64. King DJ, Bowers PM, Kehry MR, Horlick RA. PMID: 23978037.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    6. A general approach to antibody thermostabilization. MAbs. 2014; 6(5):1274-82. McConnell AD, Zhang X, Macomber JL, Chau B, Sheffer JC, Rahmanian S, Hare E, Spasojevic V, Horlick RA, King DJ, Bowers PM. PMID: 25517312.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    7. Mammalian cell display for the discovery and optimization of antibody therapeutics. Methods. 2014 Jan 01; 65(1):44-56. Bowers PM, Horlick RA, Kehry MR, Neben TY, Tomlinson GL, Altobell L, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell AD, Chau B, Berkebile AD, Hare E, Verdino P, King DJ. PMID: 23792919.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    8. Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies. J Biol Chem. 2013 Jul 05; 288(27):19861-9. Horlick RA, Macomber JL, Bowers PM, Neben TY, Tomlinson GL, Krapf IP, Dalton JL, Verdino P, King DJ. PMID: 23689374.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    9. Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation. J Biol Chem. 2013 Mar 15; 288(11):7688-96. Bowers PM, Neben TY, Tomlinson GL, Dalton JL, Altobell L, Zhang X, Macomber JL, Wu BF, Toobian RM, McConnell AD, Verdino P, Chau B, Horlick RA, King DJ. PMID: 23355464.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    10. An integrated approach to extreme thermostabilization and affinity maturation of an antibody. Protein Eng Des Sel. 2013 Feb; 26(2):151-64. McConnell AD, Spasojevich V, Macomber JL, Krapf IP, Chen A, Sheffer JC, Berkebile A, Horlick RA, Neben S, King DJ, Bowers PM. PMID: 23173178.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    11. High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation. PLoS One. 2012; 7(11):e49458. McConnell AD, Do M, Neben TY, Spasojevic V, MacLaren J, Chen AP, Altobell L, Macomber JL, Berkebile AD, Horlick RA, Bowers PM, King DJ. PMID: 23166676.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    12. Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20455-60. Bowers PM, Horlick RA, Neben TY, Toobian RM, Tomlinson GL, Dalton JL, Jones HA, Chen A, Altobell L, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell A, Chau B, Holland T, Berkebile AD, Neben SS, Boyle WJ, King DJ. PMID: 22158898.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    13. A randomized controlled study comparing once-weekly to every-2-week and every-4-week dosing of epoetin alfa in CKD patients with anemia. Clin J Am Soc Nephrol. 2010 Apr; 5(4):598-606. Pergola PE, Gartenberg G, Fu M, Sun S, Wolfson M, Bowers P. PMID: 20185602.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Erythropoiesis-stimulating agents in oncology: a study-level meta-analysis of survival and other safety outcomes. Br J Cancer. 2010 Jan 19; 102(2):301-15. Glaspy J, Crawford J, Vansteenkiste J, Henry D, Rao S, Bowers P, Berlin JA, Tomita D, Bridges K, Ludwig H. PMID: 20051958.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    15. A randomized controlled study of weekly and biweekly dosing of epoetin alfa in CKD Patients with anemia. Clin J Am Soc Nephrol. 2009 Nov; 4(11):1731-40. Pergola PE, Gartenberg G, Fu M, Wolfson M, Rao S, Bowers P. PMID: 19808215.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    16. Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly. Mol Genet Metab. 2009 Sep-Oct; 98(1-2):225-34. Roessler E, Pei W, Ouspenskaia MV, Karkera JD, Veléz JI, Banerjee-Basu S, Gibney G, Lupo PJ, Mitchell LE, Towbin JA, Bowers P, Belmont JW, Goldmuntz E, Baxevanis AD, Feldman B, Muenke M. PMID: 19553149.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    17. Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly. Am J Hum Genet. 2008 Jul; 83(1):18-29. Roessler E, Ouspenskaia MV, Karkera JD, Vélez JI, Kantipong A, Lacbawan F, Bowers P, Belmont JW, Towbin JA, Goldmuntz E, Feldman B, Muenke M. PMID: 18538293.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    18. Functional linkages can reveal protein complexes for structure determination. Structure. 2007 Sep; 15(9):1079-89. Kim SM, Bowers PM, Pal D, Strong M, Terwilliger TC, Kaufmann M, Eisenberg D. PMID: 17850747.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    19. Hair analysis in sled dogs (Canis lupus familiaris) illustrates a linkage of mercury exposure along the Yukon River with human subsistence food systems. Sci Total Environ. 2007 Oct 15; 385(1-3):80-5. Dunlap KL, Reynolds AJ, Bowers PM, Duffy LK. PMID: 17707466.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsPHPublic Health
    20. Natural history of anemia associated with interferon/ribavirin therapy for patients with HIV/HCV coinfection. AIDS Res Hum Retroviruses. 2007 Jan; 23(1):1-9. Henry DH, Slim J, Lamarca A, Bowers P, Leitz G. PMID: 17263626.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    21. The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J Mol Biol. 2007 Jan 12; 365(2):275-83. Goulding CW, Bowers PM, Segelke B, Lekin T, Kim CY, Terwilliger TC, Eisenberg D. PMID: 17064730.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    22. An exploratory study of total mercury levels in archaeological caribou hair from northwest Alaska. Chemosphere. 2006 Dec; 65(11):1909-14. Gerlach SC, Duffy LK, Murray MS, Bowers PM, Adams R, Verbrugge DA. PMID: 16876850.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    23. Utilizing logical relationships in genomic data to decipher cellular processes. FEBS J. 2005 Oct; 272(20):5110-8. Bowers PM, O'Connor BD, Cokus SJ, Sprinzak E, Yeates TO, Eisenberg D. PMID: 16218945.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    24. Use of logic relationships to decipher protein network organization. Science. 2004 Dec 24; 306(5705):2246-9. Bowers PM, Cokus SJ, Eisenberg D, Yeates TO. PMID: 15618515.
      View in: PubMed   Mentions: 40     Fields:    
    25. Once-weekly epoetin alfa improves quality of life and increases hemoglobin in anemic HIV+ patients. AIDS Res Hum Retroviruses. 2004 Oct; 20(10):1037-45. Saag MS, Bowers P, Leitz GJ, Levine AM. PMID: 15587490.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    26. Prolinks: a database of protein functional linkages derived from coevolution. Genome Biol. 2004; 5(5):R35. Bowers PM, Pellegrini M, Thompson MJ, Fierro J, Yeates TO, Eisenberg D. PMID: 15128449.
      View in: PubMed   Mentions: 113     Fields:    Translation:Animals
    27. Epoetin alfa. Clinical evolution of a pleiotropic cytokine. Arch Intern Med. 2004 Feb 09; 164(3):262-76. Henry DH, Bowers P, Romano MT, Provenzano R. PMID: 14769622.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    28. Computational method to assign microbial genes to pathways. J Cell Biochem Suppl. 2001; Suppl 37:106-9. Pellegrini M, Thompson M, Fierro J, Bowers P. PMID: 11842435.
      View in: PubMed   Mentions: 10     Fields:    
    29. Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Nat Genet. 2000 Nov; 26(3):365-9. Bamford RN, Roessler E, Burdine RD, Saplakoglu U, dela Cruz J, Splitt M, Goodship JA, Towbin J, Bowers P, Ferrero GB, Marino B, Schier AF, Shen MM, Muenke M, Casey B. PMID: 11062482.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    30. A folding transition and novel zinc finger accessory domain in the transcription factor ADR1. Nat Struct Biol. 1999 May; 6(5):478-85. Bowers PM, Schaufler LE, Klevit RE. PMID: 10331877.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
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