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Shah Prediman K

Title(s)Director, Cardiology
SchoolCedar-Sinai Medical Center
Phone310-423-4876
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    Other Positions
    Title(s)Professor, Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shah PK. Active and Passive Vaccination for Pulmonary Arterial Hypertension: A Novel Therapeutic Paradigm. J Am Coll Cardiol. 2019 May 28; 73(20):2581-2583. PMID: 31118152.
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    2. Mihailovic PM, Lio WM, Yano J, Zhou J, Zhao X, Chyu KY, Shah PK, Cercek B, Dimayuga PC. IL-7R blockade reduces post-myocardial infarction-induced atherosclerotic plaque inflammation in ApoE-/- mice. Biochem Biophys Rep. 2019 Sep; 19:100647. PMID: 31193072.
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    3. Sharifi BG, Yang M, Shah PK. Aging and GATA3-positive macrophages. Aging (Albany NY). 2019 04 24; 11(8):2179-2180. PMID: 31017875.
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    4. Onat UI, Yildirim AD, Tufanli Ö, Çimen I, Kocatürk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis. J Am Coll Cardiol. 2019 Mar 19; 73(10):1149-1169. PMID: 30871699.
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    5. Mihailovic PM, Lio WM, Herscovici R, Chyu KY, Yano J, Zhao X, Zhou J, Zhou B, Freeman MR, Yang W, Shah PK, Cercek B, Dimayuga PC. Keratin 8 is a potential self-antigen in the coronary artery disease immunopeptidome: A translational approach. PLoS One. 2019; 14(2):e0213025. PMID: 30811493.
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    6. Shah PK. Inflammation, infection and atherosclerosis. Trends Cardiovasc Med. 2019 Nov; 29(8):468-472. PMID: 30733074.
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    7. Chyu KY, Shah PK. In Pursuit of an Atherosclerosis Vaccine. Circ Res. 2018 10 26; 123(10):1121-1123. PMID: 30359192.
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    8. Yang M, Song L, Wang L, Yukht A, Ruther H, Li F, Qin M, Ghiasi H, Sharifi BG, Shah PK. Deficiency of GATA3-Positive Macrophages Improves Cardiac Function Following Myocardial Infarction or Pressure Overload Hypertrophy. J Am Coll Cardiol. 2018 08 21; 72(8):885-904. PMID: 30115228.
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    9. Arditi M, Chen S, Shah PK. Reply: Infection and Atherogenesis. J Am Coll Cardiol. 2018 08 21; 72(8):956. PMID: 30115238.
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    10. Chen S, Shimada K, Crother TR, Erbay E, Shah PK, Arditi M. Chlamydia and Lipids Engage a Common Signaling Pathway That Promotes Atherogenesis. J Am Coll Cardiol. 2018 04 10; 71(14):1553-1570. PMID: 29622163.
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    11. Arditi M, Shah PK. STOP the TRAFfic and Reduce the Plaque. J Am Coll Cardiol. 2018 02 06; 71(5):543-546. PMID: 29406860.
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    12. McCullough PA, Ballantyne CM, Sanganalmath SK, Langslet G, Baum SJ, Shah PK, Koren A, Mandel J, Davidson MH. Efficacy and Safety of Alirocumab in High-Risk Patients With Clinical Atherosclerotic Cardiovascular Disease and/or Heterozygous Familial Hypercholesterolemia (from 5 Placebo-Controlled ODYSSEY Trials). Am J Cardiol. 2018 04 15; 121(8):940-948. PMID: 29472008.
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    13. Pothineni NVK, Subramany S, Kuriakose K, Shirazi LF, Romeo F, Shah PK, Mehta JL. Infections, atherosclerosis, and coronary heart disease. Eur Heart J. 2017 Nov 14; 38(43):3195-3201. PMID: 29020241.
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    14. Mihailovic PM, Lio WM, Yano J, Zhao X, Zhou J, Chyu KY, Shah PK, Cercek B, Dimayuga PC. The cathelicidin protein CRAMP is a potential atherosclerosis self-antigen in ApoE(-/-) mice. PLoS One. 2017; 12(11):e0187432. PMID: 29091929.
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    15. Song L, Wang L, Li F, Yukht A, Qin M, Ruther H, Yang M, Chaux A, Shah PK, Sharifi BG. Bone Marrow-Derived Tenascin-C Attenuates Cardiac Hypertrophy by Controlling Inflammation. J Am Coll Cardiol. 2017 Sep 26; 70(13):1601-1615. PMID: 28935038.
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    16. Gaudet D, Gipe DA, Pordy R, Ahmad Z, Cuchel M, Shah PK, Chyu KY, Sasiela WJ, Chan KC, Brisson D, Khoury E, Banerjee P, Gusarova V, Gromada J, Stahl N, Yancopoulos GD, Hovingh GK. ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia. N Engl J Med. 2017 07 20; 377(3):296-297. PMID: 28723334.
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    17. Blom DJ, Averna MR, Meagher EA, du Toit Theron H, Sirtori CR, Hegele RA, Shah PK, Gaudet D, Stefanutti C, Vigna GB, Larrey D, Bloedon LT, Foulds P, Rader DJ, Cuchel M. Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia. Circulation. 2017 07 18; 136(3):332-335. PMID: 28716835.
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    18. Dimayuga PC, Zhao X, Yano J, Lio WM, Zhou J, Mihailovic PM, Cercek B, Shah PK, Chyu KY. Identification of apoB-100 Peptide-Specific CD8+ T Cells in Atherosclerosis. J Am Heart Assoc. 2017 Jul 15; 6(7). PMID: 28711866.
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    19. Shah PK. Sugar-Sweetened Beverage and Vascular Function: Not So Sweet After All. Arterioscler Thromb Vasc Biol. 2017 06; 37(6):1020-1021. PMID: 28539491.
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    20. Qin M, Wang L, Li F, Yang M, Song L, Tian F, Yukht A, Shah PK, Rothenberg ME, Sharifi BG. Oxidized LDL activated eosinophil polarize macrophage phenotype from M2 to M1 through activation of CD36 scavenger receptor. Atherosclerosis. 2017 Aug; 263:82-91. PMID: 28623741.
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    21. Kalra A, Shah PK, Zoghbi WA. Travel Bans and Threats to US Health Care-Our Hearts Are at Stake. JAMA Cardiol. 2017 04 01; 2(4):351-352. PMID: 28288259.
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    22. Chyu KY, Dimayuga PC, Shah PK. Vaccine against arteriosclerosis: an update. Ther Adv Vaccines. 2017 Apr; 5(2):39-47. PMID: 28515939.
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    23. Pitts R, Gunzburger E, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, Nicholls SJ, Shah PK, Tardif JC, Olsson AG, McMurray JJ, Kittelson J, Schwartz GG. Aldosterone Does Not Predict Cardiovascular Events Following Acute Coronary Syndrome in Patients Initially Without Heart Failure. J Am Heart Assoc. 2017 01 10; 6(1). PMID: 28073769.
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    24. Pitts R, Gunzburger E, Ballantyne CM, Barter PJ, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Nicholls SJ, Niesor EJ, Olsson AG, Shah PK, Tardif JC, Kittelson J, Schwartz GG. Treatment With Dalcetrapib Modifies the Relationship Between High-Density Lipoprotein Cholesterol and C-Reactive Protein. J Am Coll Cardiol. 2016 12 06; 68(22):2488-2490. PMID: 27908356.
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    25. Zhao XQ, Yuan C, Shah PK. Imaging to Assess the Effect of Anti-Inflammatory Therapy in Aortic and Carotid Atherosclerosis. J Am Coll Cardiol. 2016 10 18; 68(16):1781-1784. PMID: 27737745.
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    26. Xie Y, Kim YJ, Pang J, Kim JS, Yang Q, Wei J, Nguyen CT, Deng Z, Choi BW, Fan Z, Bairey Merz CN, Shah PK, Berman DS, Chang HJ, Li D. Coronary Atherosclerosis T1-Weighed Characterization With Integrated Anatomical Reference: Comparison With High-Risk Plaque Features Detected by Invasive Coronary Imaging. JACC Cardiovasc Imaging. 2017 06; 10(6):637-648. PMID: 27743950.
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    27. Shah PK. Temporal Change in CAC Score and Prognosis: Follow-Up Score Is Simpler and as Good as a Change in Score. JACC Cardiovasc Imaging. 2016 12; 9(12):1430-1431. PMID: 27372020.
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    28. Wakita D, Kurashima Y, Crother TR, Noval Rivas M, Lee Y, Chen S, Fury W, Bai Y, Wagner S, Li D, Lehman T, Fishbein MC, Hoffman HM, Shah PK, Shimada K, Arditi M. Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):886-97. PMID: 26941015.
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    29. Wang L, Tian F, Arias A, Yang M, Sharifi BG, Shah PK. Comparative Effects of Diet-Induced Lipid Lowering Versus Lipid Lowering Along With Apo A-I Milano Gene Therapy on Regression of Atherosclerosis. J Cardiovasc Pharmacol Ther. 2016 05; 21(3):320-8. PMID: 26499098.
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    30. Goldberger JJ, Bonow RO, Cuffe M, Liu L, Rosenberg Y, Shah PK, Smith SC, Subacius H. Effect of Beta-Blocker Dose on Survival After Acute Myocardial Infarction. J Am Coll Cardiol. 2015 Sep 29; 66(13):1431-41. PMID: 26403339.
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    31. Chyu KY, Shah PK. HDL/ApoA-1 infusion and ApoA-1 gene therapy in atherosclerosis. Front Pharmacol. 2015; 6:187. PMID: 26388776.
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    32. Honjo T, Chyu KY, Dimayuga PC, Lio WM, Yano J, Trinidad P, Zhao X, Zhou J, Cercek B, Shah PK. Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice. PLoS One. 2015; 10(6):e0131731. PMID: 26121471.
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    33. Shah PK, Parmley W, Heistad D. Remembering Kanu Chatterjee: A Gentle Giant of Cardiology. J Am Coll Cardiol. 2015 Jun 23; 65(24):2662-2663. PMID: 26088307.
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    34. Shah PK, Parmley W, Heistad D. Remembering Kanu Chatterjee: A Gentle Giant of Cardiology. Circulation. 2015 Jun 23; 131(25):2236-7. PMID: 26099958.
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    35. Wang L, Yang M, Arias A, Song L, Li F, Tian F, Qin M, Yukht A, Williamson IK, Shah PK, Sharifi BG. Splenocytes seed bone marrow of myeloablated mice: implication for atherosclerosis. PLoS One. 2015; 10(6):e0125961. PMID: 26038819.
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    36. Honjo T, Chyu KY, Dimayuga PC, Yano J, Lio WM, Trinidad P, Zhao X, Zhou J, Chen S, Cercek B, Arditi M, Shah PK. ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture. J Am Coll Cardiol. 2015 Feb 17; 65(6):546-56. PMID: 25677313.
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    37. Shah PK, Chyu KY, Dimayuga PC, Nilsson J. Vaccine for atherosclerosis. J Am Coll Cardiol. 2014 Dec 30; 64(25):2779-91. PMID: 25541132.
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    38. Shah PK. Biomarkers of plaque instability. Curr Cardiol Rep. 2014 Dec; 16(12):547. PMID: 25326730.
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    39. Fan Z, Yu W, Xie Y, Dong L, Yang L, Wang Z, Conte AH, Bi X, An J, Zhang T, Laub G, Shah PK, Zhang Z, Li D. Multi-contrast atherosclerosis characterization (MATCH) of carotid plaque with a single 5-min scan: technical development and clinical feasibility. J Cardiovasc Magn Reson. 2014 Jul 25; 16:53. PMID: 25184808.
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    40. Tian F, Wang L, Arias A, Yang M, Sharifi BG, Shah PK. Comparative antiatherogenic effects of intravenous AAV8- and AAV2-mediated ApoA-IMilano gene transfer in hypercholesterolemic mice. J Cardiovasc Pharmacol Ther. 2015 Jan; 20(1):66-75. PMID: 24742767.
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    41. Chyu KY, Lio WM, Dimayuga PC, Zhou J, Zhao X, Yano J, Trinidad P, Honjo T, Cercek B, Shah PK. Cholesterol lowering modulates T cell function in vivo and in vitro. PLoS One. 2014; 9(3):e92095. PMID: 24647529.
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    42. Chyu KY, Shah PK. Advances in immune-modulating therapies to treat atherosclerotic cardiovascular diseases. Ther Adv Vaccines. 2014 Mar; 2(2):56-66. PMID: 24757525.
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    43. Toth PP, Shah PK, Wilkinson MJ, Davidson MH, McCullough PA. Use of microsomal triglyceride transfer protein inhibitors in patients with homozygous familial hypercholesterolemia: translating clinical trial experience into clinical practice. Rev Cardiovasc Med. 2014; 15(1):1-10. PMID: 24762461.
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    44. Zhou J, Dimayuga PC, Zhao X, Yano J, Lio WM, Trinidad P, Honjo T, Cercek B, Shah PK, Chyu KY. CD8(+)CD25(+) T cells reduce atherosclerosis in apoE(-/-) mice. Biochem Biophys Res Commun. 2014 Jan 17; 443(3):864-70. PMID: 24342615.
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    45. Shah PK. Can carotid plaque predict coronary plaque? JACC Cardiovasc Imaging. 2013 Nov; 6(11):1168-71. PMID: 24229769.
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    46. Shah PK. Jekyll and Hyde of HDL: a lipoprotein with a split personality. Eur Heart J. 2013 Dec; 34(46):3531-4. PMID: 24062336.
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    47. Chyu KY, Shah PK. Can we vaccinate against atherosclerosis? J Cardiovasc Pharmacol Ther. 2014 Jan; 19(1):77-82. PMID: 24038015.
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    48. Sondermeijer BM, Rana JS, Arsenault BJ, Shah PK, Kastelein JJ, Wareham NJ, Boekholdt SM, Khaw KT. Non-HDL cholesterol vs. apo B for risk of coronary heart disease in healthy individuals: the EPIC-Norfolk prospective population study. Eur J Clin Invest. 2013 Oct; 43(10):1009-15. PMID: 23859101.
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    49. Shah PK. Rapid Detection of Subclinical Atherosclerosis: Potential Implications for Primary Prevention in LMIC. Glob Heart. 2013 Jun; 8(2):91-3. PMID: 25690373.
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    50. Dimayuga PC, Chyu KY, Lio WM, Zhao X, Yano J, Zhou J, Honjo T, Shah PK, Cercek B. Reduced neointima formation after arterial injury in CD4-/- mice is mediated by CD8+CD28hi T cells. J Am Heart Assoc. 2013 May 23; 2(3):e000155. PMID: 23702879.
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    51. Nilsson J, Wigren M, Shah PK. Vaccines against atherosclerosis. Expert Rev Vaccines. 2013 Mar; 12(3):311-21. PMID: 23496670.
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    52. Wang L, Shah PK, Wang W, Song L, Yang M, Sharifi BG. Tenascin-C deficiency in apo E-/- mouse increases eotaxin levels: implications for atherosclerosis. Atherosclerosis. 2013 Apr; 227(2):267-74. PMID: 23433402.
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    53. Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, Chaitman BR, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Mundl H, Nicholls SJ, Shah PK, Tardif JC, Wright RS. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012 Nov 29; 367(22):2089-99. PMID: 23126252.
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    54. Li F, Yang M, Wang L, Williamson I, Tian F, Qin M, Shah PK, Sharifi BG. Autofluorescence contributes to false-positive intracellular Foxp3 staining in macrophages: a lesson learned from flow cytometry. J Immunol Methods. 2012 Dec 14; 386(1-2):101-7. PMID: 23046996.
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    55. Ibebuogu UN, Cercek B, Makkar R, Dinh H, Kwarteng C, Mirocha J, Hussaini A, Singh S, Dohad S, Shah PK, Khorsandi M, Kar S. Comparison between transradial and transfemoral percutaneous coronary intervention in acute ST-elevation myocardial infarction. Am J Cardiol. 2012 Nov 01; 110(9):1262-5. PMID: 22840847.
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    56. Shah PK. Should severe aortic stenosis be operated on before symptom onset? Severe aortic stenosis should not be operated on before symptom onset. Circulation. 2012 Jul 03; 126(1):118-25. PMID: 22753533.
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    57. Chen S, Lee Y, Crother TR, Fishbein M, Zhang W, Yilmaz A, Shimada K, Schulte DJ, Lehman TJ, Shah PK, Arditi M. Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease. Arterioscler Thromb Vasc Biol. 2012 Aug; 32(8):e60-71. PMID: 22628430.
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    58. Rana JS, Boekholdt SM, Kastelein JJ, Shah PK. The role of non-HDL cholesterol in risk stratification for coronary artery disease. Curr Atheroscler Rep. 2012 Apr; 14(2):130-4. PMID: 22203405.
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    59. Shah PK. Cholesteryl ester transfer protein inhibition and endothelial function: enough with the surrogates. Eur Heart J. 2012 Apr; 33(7):819-21. PMID: 22355037.
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    60. Chyu KY, Zhao X, Dimayuga PC, Zhou J, Li X, Yano J, Lio WM, Chan LF, Kirzner J, Trinidad P, Cercek B, Shah PK. CD8+ T cells mediate the athero-protective effect of immunization with an ApoB-100 peptide. PLoS One. 2012; 7(2):e30780. PMID: 22347402.
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    61. Wang L, Wang W, Shah PK, Song L, Yang M, Sharifi BG. Deletion of tenascin-C gene exacerbates atherosclerosis and induces intraplaque hemorrhage in Apo-E-deficient mice. Cardiovasc Pathol. 2012 Sep-Oct; 21(5):398-413. PMID: 22300502.
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    62. Cesena FH, Dimayuga PC, Yano J, Zhao X, Kirzner J, Zhou J, Chan LF, Lio WM, Cercek B, Shah PK, Chyu KY. Immune-modulation by polyclonal IgM treatment reduces atherosclerosis in hypercholesterolemic apoE-/- mice. Atherosclerosis. 2012 Jan; 220(1):59-65. PMID: 22062590.
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    63. Chyu KY, Peter A, Shah PK. Progress in HDL-based therapies for atherosclerosis. Curr Atheroscler Rep. 2011 Oct; 13(5):405-12. PMID: 21744164.
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    64. Falk E, Shah PK. The SHAPE guideline: ahead of its time or just in time? Curr Atheroscler Rep. 2011 Oct; 13(5):345-52. PMID: 21811799.
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    65. Morrissey RP, Czer L, Shah PK. Chronic heart failure: current evidence, challenges to therapy, and future directions. Am J Cardiovasc Drugs. 2011 Jun 01; 11(3):153-71. PMID: 21619379.
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    66. Dimayuga PC, Chyu KY, Kirzner J, Yano J, Zhao X, Zhou J, Shah PK, Cercek B. Enhanced neointima formation following arterial injury in immune deficient Rag-1-/- mice is attenuated by adoptive transfer of CD8 T cells. PLoS One. 2011; 6(5):e20214. PMID: 21629656.
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    67. Chyu KY, Nilsson J, Shah PK. Immune mechanisms in atherosclerosis and potential for an atherosclerosis vaccine. Discov Med. 2011 May; 11(60):403-12. PMID: 21616039.
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    68. Meisel SR, Xu XP, Edgington TS, Cercek B, Ong J, Kaul S, Shah PK. Dose-dependent modulation of tissue factor protein and procoagulant activity in human monocyte-derived macrophages by oxidized low density lipoprotein. J Atheroscler Thromb. 2011; 18(7):596-603. PMID: 21467727.
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    69. Shah PK. Atherosclerosis: targeting endogenous apo A-I--a new approach for raising HDL. Nat Rev Cardiol. 2011 Apr; 8(4):187-8. PMID: 21364534.
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    70. Nakanishi R, Rajani R, Shmilovich H, Shah PK, Berman DS. Multiple myocardial crypts on cardiac CT angiography in a symptomatic patient with troponin elevation. Int J Cardiol. 2011 Nov 17; 153(1):e10-1. PMID: 21296435.
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    71. Shah PK. Residual risk and high-density lipoprotein cholesterol levels: is there a relationship? Rev Cardiovasc Med. 2011; 12(2):e55-9. PMID: 21796083.
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    72. Chyu KY, Shah PK. Emerging therapies for atherosclerosis prevention and management. Cardiol Clin. 2011 Feb; 29(1):123-35. PMID: 21257104.
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    73. Shah PK. Evolving concepts on benefits and risks associated with therapeutic strategies to raise HDL. Curr Opin Cardiol. 2010 Nov; 25(6):603-8. PMID: 20827180.
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    74. Troughton RW, Ritzema J, Eigler NL, Melton IC, Krum H, Adamson PB, Kar S, Shah PK, Whiting JS, Heywood JT, Rosero S, Singh JP, Saxon L, Matthews R, Crozier IG, Abraham WT. Direct left atrial pressure monitoring in severe heart failure: long-term sensor performance. J Cardiovasc Transl Res. 2011 Feb; 4(1):3-13. PMID: 20945124.
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    75. Song L, Wang L, Shah PK, Chaux A, Sharifi BG. Bioengineered vascular graft grown in the mouse peritoneal cavity. J Vasc Surg. 2010 Oct; 52(4):994-1002, 1002.e1-2. PMID: 20692791.
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    76. Shah PK. Screening asymptomatic subjects for subclinical atherosclerosis: can we, does it matter, and should we? J Am Coll Cardiol. 2010 Jul 06; 56(2):98-105. PMID: 20620724.
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    77. Bairey Merz CN, Mark S, Boyan BD, Jacobs AK, Shah PK, Shaw LJ, Taylor D, Marbán E. Proceedings from the scientific symposium: Sex differences in cardiovascular disease and implications for therapies. J Womens Health (Larchmt). 2010 Jun; 19(6):1059-72. PMID: 20500123.
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    78. Naqvi TZ, Mendoza F, Rafii F, Gransar H, Guerra M, Lepor N, Berman DS, Shah PK. High prevalence of ultrasound detected carotid atherosclerosis in subjects with low Framingham risk score: potential implications for screening for subclinical atherosclerosis. J Am Soc Echocardiogr. 2010 Aug; 23(8):809-15. PMID: 20554155.
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    79. Meisel SR, Ouyang Y, Fishbein MC, Edgington TS, Ruan XM, Cercek B, Shah PK, Chaux A. Prolonged hypercholesterolemia-induced tissue factor expression in rabbit vein grafts: a potential mechanism for graft failure. Coron Artery Dis. 2010 Mar; 21(2):97-103. PMID: 20087175.
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    80. Ritzema J, Troughton R, Melton I, Crozier I, Doughty R, Krum H, Walton A, Adamson P, Kar S, Shah PK, Richards M, Eigler NL, Whiting JS, Haas GJ, Heywood JT, Frampton CM, Abraham WT. Physician-directed patient self-management of left atrial pressure in advanced chronic heart failure. Circulation. 2010 Mar 09; 121(9):1086-95. PMID: 20176990.
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    81. Dhesi P, Ng R, Shehata MM, Shah PK. Ventricular tachycardia after ingestion of ayurveda herbal antidiarrheal medication containing aconitum. Arch Intern Med. 2010 Feb 08; 170(3):303-5. PMID: 20142579.
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    82. Shah PK. The SHAPE paradigm: a commentary. Circ Cardiovasc Qual Outcomes. 2010 Jan; 3(1):106-9. PMID: 20123677.
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    83. Ng CY, Stevens S, Buch M, Dohad S, Shah PK, Cercek B, Chyu KY. Giant saphenous vein graft aneurysm causing left atrial compression and cardiogenic shock. Rev Cardiovasc Med. 2010; 11(3):e170-5. PMID: 21045770.
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    84. Arsenault BJ, Rana JS, Stroes ES, Després JP, Shah PK, Kastelein JJ, Wareham NJ, Boekholdt SM, Khaw KT. Beyond low-density lipoprotein cholesterol: respective contributions of non-high-density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and women. J Am Coll Cardiol. 2009 Dec 29; 55(1):35-41. PMID: 20117361.
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    85. Shah PK. The yin and yang of cholesteryl ester transfer protein in cardiovascular disease. Circulation. 2009 Dec 15; 120(24):2408-10. PMID: 19948970.
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    86. Li F, Tian F, Wang L, Williamson IK, Sharifi BG, Shah PK. Pleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-{gamma}/JAK/STAT1 signaling is critical for the expression of PTN in macrophages. FASEB J. 2010 Mar; 24(3):810-22. PMID: 19917672.
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    87. Eshaghian S, Shah PK, Kaul S. Advances in antiplatelet treatment for acute coronary syndromes. Heart. 2010 May; 96(9):656-61. PMID: 19910292.
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    88. Nilsson J, Wigren M, Shah PK. Regulatory T cells and the control of modified lipoprotein autoimmunity-driven atherosclerosis. Trends Cardiovasc Med. 2009 Nov; 19(8):272-6. PMID: 20447570.
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    89. Shah PK. Imaging inflammation in atherosclerosis another step forward. JACC Cardiovasc Imaging. 2009 Oct; 2(10):1223-5. PMID: 19833313.
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    90. Dimayuga PC, Cesena FH, Chyu KY, Yano J, Amorn A, Fishbein MC, Shah PK, Cercek B. Natural antibodies and complement modulate intimal thickening after arterial injury. Am J Physiol Regul Integr Comp Physiol. 2009 Nov; 297(5):R1593-600. PMID: 19776252.
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    91. Naik H, White AJ, Chakravarty T, Forrester J, Fontana G, Kar S, Shah PK, Weiss RE, Makkar R. A meta-analysis of 3,773 patients treated with percutaneous coronary intervention or surgery for unprotected left main coronary artery stenosis. JACC Cardiovasc Interv. 2009 Aug; 2(8):739-47. PMID: 19695542.
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    92. Shah PK. Diabetes: Does screening for inducible ischemia improve outcomes? Nat Rev Cardiol. 2009 Jul; 6(7):452-3. PMID: 19554005.
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    93. Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M. TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol. 2008 Nov 15; 181(10):7176-85. PMID: 18981139.
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    94. Shah PK. Inflammation and plaque vulnerability. Cardiovasc Drugs Ther. 2009 Feb; 23(1):31-40. PMID: 18949542.
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    95. Matsumoto M, Dimayuga PC, Wang C, Kirzner J, Cercek M, Yano J, Chyu KY, Shah PK, Cercek B. Exogenous heat shock protein-70 inhibits cigarette smoke-induced intimal thickening. Am J Physiol Regul Integr Comp Physiol. 2008 Oct; 295(4):R1320-7. PMID: 18703412.
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    96. White AJ, Kedia G, Mirocha JM, Lee MS, Forrester JS, Morales WC, Dohad S, Kar S, Czer LS, Fontana GP, Trento A, Shah PK, Makkar RR. Comparison of coronary artery bypass surgery and percutaneous drug-eluting stent implantation for treatment of left main coronary artery stenosis. JACC Cardiovasc Interv. 2008 Jun; 1(3):236-45. PMID: 19463306.
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    97. Boden WE, Shah PK, Gupta V, Ohman EM. Contemporary approach to the diagnosis and management of non-ST-segment elevation acute coronary syndromes. Prog Cardiovasc Dis. 2008 Mar-Apr; 50(5):311-51. PMID: 18313479.
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    98. Goldberger JJ, Bonow RO, Cuffe M, Dyer A, Greenland P, Rosenberg Y, O'Rourke R, Shah PK, Smith S. Post-myocardial infarction beta-blocker therapy: the bradycardia conundrum. Rationale and design for the Pacemaker & beta-blocker therapy post-MI (PACE-MI) trial. Am Heart J. 2008 Mar; 155(3):455-64. PMID: 18294477.
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    99. Shah PK. High-density lipoprotein mimetics: focus on synthetic high-density lipoprotein. Am J Cardiol. 2007 Dec 03; 100(11 A):S62-7. PMID: 18047855.
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    100. Schiopu A, Frendéus B, Jansson B, Söderberg I, Ljungcrantz I, Araya Z, Shah PK, Carlsson R, Nilsson J, Fredrikson GN. Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice. J Am Coll Cardiol. 2007 Dec 11; 50(24):2313-8. PMID: 18068040.
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    101. Shah PK. Distal embolization after percutaneous coronary interventions: prediction, prevention, and relevance. J Am Coll Cardiol. 2007 Oct 23; 50(17):1647-8. PMID: 17950145.
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    102. Shah PK. Molecular mechanisms of plaque instability. Curr Opin Lipidol. 2007 Oct; 18(5):492-9. PMID: 17885418.
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    103. Chyu KY, Nilsson J, Shah PK. Immunization for atherosclerosis. Curr Atheroscler Rep. 2007 Aug; 9(2):104-9. PMID: 17877918.
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    104. Kupferwasser LI, Amorn AM, Kapoor N, Lee MS, Kar S, Cercek B, Dohad S, Mirocha J, Forrester JS, Shah PK, Makkar RR. Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction. Catheter Cardiovasc Interv. 2007 Jul 01; 70(1):1-8. PMID: 17580366.
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    105. Shah PK. Innate immune pathway links obesity to insulin resistance. Circ Res. 2007 Jun 08; 100(11):1531-3. PMID: 17556663.
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    106. Kaul S, Shah PK, Diamond GA. As time goes by: current status and future directions in the controversy over stenting. J Am Coll Cardiol. 2007 Jul 10; 50(2):128-37. PMID: 17616296.
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    107. Chyu KY, Shah PK. Choking off plaque neovascularity: a promising atheroprotective strategy or a double-edged sword? Arterioscler Thromb Vasc Biol. 2007 May; 27(5):993-5. PMID: 17442896.
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    108. Diamond GA, Kaul S, Shah PK. Screen testing cardiovascular prevention in asymptomatic diabetic patients. J Am Coll Cardiol. 2007 May 15; 49(19):1915-7. PMID: 17498574.
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    109. Chyu KY, Nilsson J, Shah PK. Active and passive immunization for atherosclerosis. Curr Opin Mol Ther. 2007 Apr; 9(2):176-82. PMID: 17458172.
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    110. Cooper LT, Mensah GA, Baddour LM, Dunbar SB, Kaplan EL, Wilson WR, Shah PK. ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats. Task Force III: prevention and control of cardiovascular complications of emerging infectious diseases and potential biological terrorism agents and diseases. Circulation. 2007 Mar 27; 115(12):1681-9. PMID: 17506122.
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    111. Cooper LT, Mensah GA, Baddour LM, Dunbar SB, Kaplan EL, Wilson WR, Shah PK. ACCF/AHA/CDC Conference report on emerging infectious diseases and biological terrorism threats. Task Force III: prevention and control of cardiovascular complications of emerging infectious diseases and potential biological terrorism agents and diseases. J Am Coll Cardiol. 2007 Mar 27; 49(12):1398-406. PMID: 17394981.
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    112. Mensah GA, Grant AO, Pepine CJ, Baddour LM, Cooper LT, Dunbar SB, Froelicher ES, Greenlund KJ, Kaplan EL, Kloner RA, Labarthe DR, Luepker RV, Madjid M, Muller JE, O'Connor S, Ornato JP, Robertson RM, Roy MJ, Shah PK, Taubert KA, Wilson WR, Zheng ZJ, Harrington RA, Abrams J, Anderson JL, Bates ER, Eisenberg MJ, Grines CL, Hlatky MA, Lichtenberg RC, Lindner JR, Pohost GM, Schofield RS, Shubrooks SJ, Stein JH, Tracy CM, Vogel RA, Wesley DJ. ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases. J Am Coll Cardiol. 2007 Mar 27; 49(12):1373-412. PMID: 17394977.
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    113. Eshaghian S, Kaul S, Amin S, Shah PK, Diamond GA. Role of clopidogrel in managing atherothrombotic cardiovascular disease. Ann Intern Med. 2007 Mar 20; 146(6):434-41. PMID: 17371888.
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    114. Mensah GA, Grant AO, Pepine CJ, Baddour LM, Cooper LT, Dunbar SB, Froelicher ES, Greenlund KJ, Kaplan EL, Kloner RA, Labarthe DR, Luepker RV, Madjid M, Muller JE, O'Connor S, Ornato JP, Robertson RM, Roy MJ, Shah PK, Taubert KA, Wilson WR, Zheng ZJ, Harrington RA, Abrams J, Anderson JL, Bates ER, Eisenberg MJ, Grines CL, Hlatky MA, Lichtenberg RC, Lindner JR, Pohost GM, Schofield RS, Shubrooks SJ, Stein JH, Tracy CM, Vogel RA, Wesley DJ. ACCF/AHA/CDC conference report on emerging infectious diseases and biological terrorism threats: the clinical and public health implications for the prevention and control of cardiovascular diseases. Circulation. 2007 Mar 27; 115(12):1656-95. PMID: 17372165.
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    115. Fredrikson GN, Hedblad B, Berglund G, Alm R, Nilsson JA, Schiopu A, Shah PK, Nilsson J. Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease. Stroke. 2007 May; 38(5):1495-500. PMID: 17363723.
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    116. Cheng VY, Lepor NE, Madyoon H, Eshaghian S, Naraghi AL, Shah PK. Presence and severity of noncalcified coronary plaque on 64-slice computed tomographic coronary angiography in patients with zero and low coronary artery calcium. Am J Cardiol. 2007 May 01; 99(9):1183-6. PMID: 17478137.
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    117. Fredrikson GN, Lindholm MW, Ljungcrantz I, Söderberg I, Shah PK, Nilsson J. Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice. Autoimmunity. 2007 Mar; 40(2):122-30. PMID: 17453711.
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    118. Shah PK. Emerging HDL-based therapies for atherothrombotic vascular disease. Curr Treat Options Cardiovasc Med. 2007 Feb; 9(1):60-70. PMID: 17378977.
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    119. Fredrikson GN, Schiopu A, Berglund G, Alm R, Shah PK, Nilsson J. Autoantibody against the amino acid sequence 661-680 in apo B-100 is associated with decreased carotid stenosis and cardiovascular events. Atherosclerosis. 2007 Oct; 194(2):e188-92. PMID: 17214995.
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    120. Nilsson J, Nordin Fredrikson G, Schiopu A, Shah PK, Jansson B, Carlsson R. Oxidized LDL antibodies in treatment and risk assessment of atherosclerosis and associated cardiovascular disease. Curr Pharm Des. 2007; 13(10):1021-30. PMID: 17430165.
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    121. Shah PK. Apolipoprotein A-I/HDL infusion therapy for plaque stabilization-regression: a novel therapeutic approach. Curr Pharm Des. 2007; 13(10):1031-8. PMID: 17430166.
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    122. Eshaghian S, Kaul S, Shah PK. Cardiac amyloidosis: new insights into diagnosis and management. Rev Cardiovasc Med. 2007; 8(4):189-99. PMID: 18192942.
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    123. Shah PK. Inhibition of CETP as a novel therapeutic strategy for reducing the risk of atherosclerotic disease. Eur Heart J. 2007 Jan; 28(1):5-12. PMID: 17121756.
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    124. Forrester JS, Shah PK. Emerging strategies for increasing high-density lipoprotein. Am J Cardiol. 2006 Dec 01; 98(11):1542-9. PMID: 17126667.
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    125. Forrester JS, Shah PK, Makkar RR. Myocardial regeneration by stem cells: seeing the unseeable. J Am Coll Cardiol. 2006 Oct 17; 48(8):1722-4. PMID: 17045911.
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    126. Wang L, Sharifi BG, Pan T, Song L, Yukht A, Shah PK. Bone marrow transplantation shows superior atheroprotective effects of gene therapy with apolipoprotein A-I Milano compared with wild-type apolipoprotein A-I in hyperlipidemic mice. J Am Coll Cardiol. 2006 Oct 03; 48(7):1459-68. PMID: 17010811.
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    127. Kaul S, Zadeh AA, Shah PK. Homocysteine hypothesis for atherothrombotic cardiovascular disease: not validated. J Am Coll Cardiol. 2006 Sep 05; 48(5):914-23. PMID: 16949480.
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    128. Iida K, Luo H, Hagisawa K, Akima T, Shah PK, Naqvi TZ, Siegel RJ. Noninvasive low-frequency ultrasound energy causes vasodilation in humans. J Am Coll Cardiol. 2006 Aug 01; 48(3):532-7. PMID: 16875980.
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    129. Fredrikson GN, Berglund G, Alm R, Nilsson JA, Shah PK, Nilsson J. Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide. J Lipid Res. 2006 Sep; 47(9):2049-54. PMID: 16809787.
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    130. Tung R, Kaul S, Diamond GA, Shah PK. Narrative review: drug-eluting stents for the management of restenosis: a critical appraisal of the evidence. Ann Intern Med. 2006 Jun 20; 144(12):913-9. PMID: 16785479.
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    131. Naghavi M, Falk E, Hecht HS, Jamieson MJ, Kaul S, Berman D, Fayad Z, Budoff MJ, Rumberger J, Naqvi TZ, Shaw LJ, Faergeman O, Cohn J, Bahr R, Koenig W, Demirovic J, Arking D, Herrera VL, Badimon J, Goldstein JA, Rudy Y, Airaksinen J, Schwartz RS, Riley WA, Mendes RA, Douglas P, Shah PK. From vulnerable plaque to vulnerable patient--Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report. Am J Cardiol. 2006 Jul 17; 98(2A):2H-15H. PMID: 16843744.
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    132. Sharifi BG, Zeng Z, Wang L, Song L, Chen H, Qin M, Sierra-Honigmann MR, Wachsmann-Hogiu S, Shah PK. Pleiotrophin induces transdifferentiation of monocytes into functional endothelial cells. Arterioscler Thromb Vasc Biol. 2006 Jun; 26(6):1273-80. PMID: 16614316.
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    133. Lee MS, Shah AP, Dang N, Berman D, Forrester J, Shah PK, Aragon J, Jamal F, Makkar RR. Coronary sinus is dilated and outwardly displaced in patients with mitral regurgitation: quantitative angiographic analysis. Catheter Cardiovasc Interv. 2006 Mar; 67(3):490-4. PMID: 16475163.
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    134. Faria-Neto JR, Chyu KY, Li X, Dimayuga PC, Ferreira C, Yano J, Cercek B, Shah PK. Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice. Atherosclerosis. 2006 Nov; 189(1):83-90. PMID: 16386745.
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    135. Lee MS, Kapoor N, Jamal F, Czer L, Aragon J, Forrester J, Kar S, Dohad S, Kass R, Eigler N, Trento A, Shah PK, Makkar RR. Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol. 2006 Feb 21; 47(4):864-70. PMID: 16487857.
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    136. Shah PK. Thrombogenic risk factors for atherothrombosis. Rev Cardiovasc Med. 2006; 7(1):10-6. PMID: 16534491.
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    137. Moses JW, Shah PK. Enhanced long-term antiplatelet therapy after coronary stenting. J Invasive Cardiol. 2005 Dec; 17(12):669-76. PMID: 16327052.
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    138. Shah PK, Chyu KY, Fredrikson GN, Nilsson J. Immunomodulation of atherosclerosis with a vaccine. Nat Clin Pract Cardiovasc Med. 2005 Dec; 2(12):639-46. PMID: 16306920.
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    139. Makkar RR, Price MJ, Lill M, Frantzen M, Takizawa K, Kleisli T, Zheng J, Kar S, McClelan R, Miyamota T, Bick-Forrester J, Fishbein MC, Shah PK, Forrester JS, Sharifi B, Chen PS, Qayyum M. Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther. 2005 Dec; 10(4):225-33. PMID: 16382259.
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    140. Kangavari S, Gupta N, Shah PK, Chen PS. Complete heart block induced and terminated by a premature contraction. J Cardiovasc Electrophysiol. 2005 Dec; 16(12):1394. PMID: 16403082.
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    141. Kaul S, Shah PK. ApoA-I Milano/phospholipid complexes emerging pharmacological strategies and medications for the prevention of atherosclerotic plaque progression. Curr Drug Targets Cardiovasc Haematol Disord. 2005 Dec; 5(6):471-9. PMID: 16503867.
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    142. Cercek M, Matsumoto M, Li H, Chyu KY, Peter A, Shah PK, Dimayuga PC. Autocrine role of vascular IL-15 in intimal thickening. Biochem Biophys Res Commun. 2006 Jan 13; 339(2):618-23. PMID: 16321364.
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    143. Chyu KY, Zhao X, Reyes OS, Babbidge SM, Dimayuga PC, Yano J, Cercek B, Fredrikson GN, Nilsson J, Shah PK. Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (-/-) mice. Biochem Biophys Res Commun. 2005 Dec 30; 338(4):1982-9. PMID: 16288717.
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    144. Shah PK, Chyu KY. Apolipoprotein A-I mimetic peptides: potential role in atherosclerosis management. Trends Cardiovasc Med. 2005 Nov; 15(8):291-6. PMID: 16297766.
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    145. Price MJ, Chou CC, Frantzen M, Miyamoto T, Kar S, Lee S, Shah PK, Martin BJ, Lill M, Forrester JS, Chen PS, Makkar RR. Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic properties. Int J Cardiol. 2006 Aug 10; 111(2):231-9. PMID: 16246440.
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    146. Dimayuga PC, Li H, Chyu KY, Fredrikson GN, Nilsson J, Fishbein MC, Shah PK, Cercek B. T cell modulation of intimal thickening after vascular injury: the bimodal role of IFN-gamma in immune deficiency. Arterioscler Thromb Vasc Biol. 2005 Dec; 25(12):2528-34. PMID: 16224059.
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    147. Shah PK. Preservation of cardiac extracellular matrix by passive myocardial restraint: an emerging new therapeutic paradigm in the prevention of adverse remodeling and progressive heart failure. Circulation. 2005 Aug 30; 112(9):1245-7. PMID: 16129809.
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    148. Sharifi BG, Wu K, Wang L, Ong JM, Zhou X, Shah PK. AAV serotype-dependent apolipoprotein A-I Milano gene expression. Atherosclerosis. 2005 Aug; 181(2):261-9. PMID: 16039279.
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    149. Qiao JH, Doherty TM, Fishbein MC, Salusky IB, Luthringer DL, Fitzpatrick LA, Shah PK, Rajavashisth TB. Calcification of the coronary arteries in the absence of atherosclerotic plaque. Mayo Clin Proc. 2005 Jun; 80(6):807-9. PMID: 15948300.
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    150. Doherty TM, Shah PK, Arditi M. Lipopolysaccharide, toll-like receptors, and the immune contribution to atherosclerosis. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):e38; author reply e38-9. PMID: 15863713.
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    151. Neyer J, Espinoza C, Luppen L, Dohety TM, Tripathi SC, Uzui H, Tripathi PV, Lee G, Shah PK, Rajavashisth TB. A comparison of anion-exchange and steric-exclusion HPLC assays of mouse plasma lipoproteins. J Lipid Res. 2005 Aug; 46(8):1786-95. PMID: 15772432.
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    152. Fredrikson GN, Andersson L, Söderberg I, Dimayuga P, Chyu KY, Shah PK, Nilsson J. Atheroprotective immunization with MDA-modified apo B-100 peptide sequences is associated with activation of Th2 specific antibody expression. Autoimmunity. 2005 Mar; 38(2):171-9. PMID: 16040338.
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    153. Shah PK. Insights into the molecular mechanisms of plaque rupture and thrombosis. Indian Heart J. 2005 Jan-Feb; 57(1):21-30. PMID: 15852890.
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    154. Michelsen KS, Doherty TM, Shah PK, Arditi M. Role of Toll-like receptors in atherosclerosis. Circ Res. 2004 Dec 10; 95(12):e96-7. PMID: 15591233.
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    155. Shah PK, Chyu KY, Fredrikson GN, Nilsson J. Vaccination for atherosclerosis: a novel therapeutic paradigm. Expert Rev Vaccines. 2004 Dec; 3(6):711-6. PMID: 15606356.
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    156. Kangavari S, Matetzky S, Shah PK, Yano J, Chyu KY, Fishbein MC, Cercek B. Smoking increases inflammation and metalloproteinase expression in human carotid atherosclerotic plaques. J Cardiovasc Pharmacol Ther. 2004 Dec; 9(4):291-8. PMID: 15678248.
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    157. Michelsen KS, Doherty TM, Shah PK, Arditi M. TLR signaling: an emerging bridge from innate immunity to atherogenesis. J Immunol. 2004 Nov 15; 173(10):5901-7. PMID: 15528321.
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    158. Taylor KD, Scheuner MT, Yang H, Wang Y, Haritunians T, Fischel-Ghodsian N, Shah PK, Forrester JS, Knatterud G, Rotter JI. Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts. Genet Med. 2004 Nov-Dec; 6(6):481-6. PMID: 15545743.
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    159. Nilsson J, Hansson GK, Shah PK. Immunomodulation of atherosclerosis: implications for vaccine development. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):18-28. PMID: 15514204.
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    160. Schiopu A, Bengtsson J, Söderberg I, Janciauskiene S, Lindgren S, Ares MP, Shah PK, Carlsson R, Nilsson J, Fredrikson GN. Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis. Circulation. 2004 Oct 05; 110(14):2047-52. PMID: 15451805.
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    161. Kaul S, Coin B, Hedayiti A, Yano J, Cercek B, Chyu KY, Shah PK. Rapid reversal of endothelial dysfunction in hypercholesterolemic apolipoprotein E-null mice by recombinant apolipoprotein A-I(Milano)-phospholipid complex. J Am Coll Cardiol. 2004 Sep 15; 44(6):1311-9. PMID: 15364338.
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    162. Li X, Chyu KY, Faria Neto JR, Yano J, Nathwani N, Ferreira C, Dimayuga PC, Cercek B, Kaul S, Shah PK. Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice. Circulation. 2004 Sep 21; 110(12):1701-5. PMID: 15353488.
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    163. Chyu KY, Reyes OS, Zhao X, Yano J, Dimayuga P, Nilsson J, Cercek B, Shah PK. Timing affects the efficacy of LDL immunization on atherosclerotic lesions in apo E (-/-) mice. Atherosclerosis. 2004 Sep; 176(1):27-35. PMID: 15306171.
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    164. Doherty TM, Fitzpatrick LA, Inoue D, Qiao JH, Fishbein MC, Detrano RC, Shah PK, Rajavashisth TB. Molecular, endocrine, and genetic mechanisms of arterial calcification. Endocr Rev. 2004 Aug; 25(4):629-72. PMID: 15294885.
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    165. Anazawa T, Dimayuga PC, Li H, Tani S, Bradfield J, Chyu KY, Kaul S, Shah PK, Cercek B. Effect of exposure to cigarette smoke on carotid artery intimal thickening: the role of inducible NO synthase. Arterioscler Thromb Vasc Biol. 2004 Sep; 24(9):1652-8. PMID: 15271786.
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    166. Michelsen KS, Wong MH, Shah PK, Zhang W, Yano J, Doherty TM, Akira S, Rajavashisth TB, Arditi M. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10679-84. PMID: 15249654.
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    167. Tani S, Dimayuga PC, Anazawa T, Chyu KY, Li H, Shah PK, Cercek B. Aberrant antibody responses to oxidized LDL and increased intimal thickening in apoE-/- mice exposed to cigarette smoke. Atherosclerosis. 2004 Jul; 175(1):7-14. PMID: 15186941.
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    168. Wallner K, Li C, Shah PK, Wu KJ, Schwartz SM, Sharifi BG. EGF-Like domain of tenascin-C is proapoptotic for cultured smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004 Aug; 24(8):1416-21. PMID: 15178565.
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    169. Chyu KY, Babbidge SM, Zhao X, Dandillaya R, Rietveld AG, Yano J, Dimayuga P, Cercek B, Shah PK. Differential effects of green tea-derived catechin on developing versus established atherosclerosis in apolipoprotein E-null mice. Circulation. 2004 May 25; 109(20):2448-53. PMID: 15136500.
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    170. Chyu KY, Dimayuga PC, Zhao X, Nilsson J, Shah PK, Cercek B. Altered AP-1/Ref-1 redox pathway and reduced proliferative response in iNOS-deficient vascular smooth muscle cells. Vasc Med. 2004 May; 9(3):177-83. PMID: 15675181.
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    171. Nord JE, Shah PK, Rinaldi RZ, Weisman MH. Hydroxychloroquine cardiotoxicity in systemic lupus erythematosus: a report of 2 cases and review of the literature. Semin Arthritis Rheum. 2004 Apr; 33(5):336-51. PMID: 15079764.
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    172. Finkelstein A, Hausleiter J, Doherty T, Takizawa K, Bergman J, Liu M, Rukshin V, Fishbein M, Eigler N, Shah P, Rajavashisth T, Makkar R. Intracoronary beta-irradiation enhances balloon-injury-induced tissue factor expression in the porcine injury model. Int J Cardiovasc Intervent. 2004; 6(1):20-7. PMID: 15204169.
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    173. Shah PK. Ranolazine: a new drug and a new paradigm for management of myocardial ischemia and angina. Rev Cardiovasc Med. 2004; 5(3):186-8. PMID: 15346105.
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    174. Shah PK, Chyu KY, Nilsson J. Immunotherapy for atherosclerosis: an emerging paradigm. Rev Cardiovasc Med. 2004; 5(4):194-203. PMID: 15580158.
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    175. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation. 2003 Oct 14; 108(15):1772-8. PMID: 14557340.
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    176. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Juhani Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation. 2003 Oct 07; 108(14):1664-72. PMID: 14530185.
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    177. Doherty TM, Asotra K, Fitzpatrick LA, Qiao JH, Wilkin DJ, Detrano RC, Dunstan CR, Shah PK, Rajavashisth TB. Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11201-6. PMID: 14500910.
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    178. Rukshin V, Santos R, Gheorghiu M, Shah PK, Kar S, Padmanabhan S, Azarbal B, Tsang VT, Makkar R, Samuels B, Lepor N, Geft I, Tabak S, Khorsandhi M, Buchbinder N, Eigler N, Cercek B, Hodgson K, Kaul S. A prospective, nonrandomized, open-labeled pilot study investigating the use of magnesium in patients undergoing nonacute percutaneous coronary intervention with stent implantation. J Cardiovasc Pharmacol Ther. 2003 Sep; 8(3):193-200. PMID: 14506544.
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    179. Shah PK. Pathophysiology of plaque rupture and the concept of plaque stabilization. Cardiol Clin. 2003 Aug; 21(3):303-14, v. PMID: 14621447.
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    180. Shah PK. Myocardial infarction and ischemia. J Am Coll Cardiol. 2003 Jul 16; 42(2):375-7. PMID: 12875779.
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    181. Kaul S, Rukshin V, Santos R, Azarbal B, Bisgaier CL, Johansson J, Tsang VT, Chyu KY, Cercek B, Mirocha J, Shah PK. Intramural delivery of recombinant apolipoprotein A-IMilano/phospholipid complex (ETC-216) inhibits in-stent stenosis in porcine coronary arteries. Circulation. 2003 May 27; 107(20):2551-4. PMID: 12742990.
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    182. Shah PK. Inflammation, neointimal hyperplasia, and restenosis: as the leukocytes roll, the arteries thicken. Circulation. 2003 May 06; 107(17):2175-7. PMID: 12732592.
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    183. Rukshin V, Azarbal B, Finkelstein A, Shah PK, Cercek B, Tsang V, Kaul S. Effects of GP IIb/IIIa receptor inhibitor tirofiban (aggrastat) in ex vivo canine arteriovenous shunt model of stent thrombosis. J Cardiovasc Pharmacol. 2003 Apr; 41(4):615-24. PMID: 12658064.
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    184. Doherty TM, Shah PK, Rajavashisth TB. Cellular origins of atherosclerosis: towards ontogenetic endgame? FASEB J. 2003 Apr; 17(6):592-7. PMID: 12665471.
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    185. Fredrikson GN, Hedblad B, Berglund G, Alm R, Ares M, Cercek B, Chyu KY, Shah PK, Nilsson J. Identification of immune responses against aldehyde-modified peptide sequences in apoB associated with cardiovascular disease. Arterioscler Thromb Vasc Biol. 2003 May 01; 23(5):872-8. PMID: 12649091.
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    186. Fredrikson GN, Söderberg I, Lindholm M, Dimayuga P, Chyu KY, Shah PK, Nilsson J. Inhibition of atherosclerosis in apoE-null mice by immunization with apoB-100 peptide sequences. Arterioscler Thromb Vasc Biol. 2003 May 01; 23(5):879-84. PMID: 12649092.
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    187. Cercek B, Shah PK, Noc M, Zahger D, Zeymer U, Matetzky S, Maurer G, Mahrer P. Effect of short-term treatment with azithromycin on recurrent ischaemic events in patients with acute coronary syndrome in the Azithromycin in Acute Coronary Syndrome (AZACS) trial: a randomised controlled trial. Lancet. 2003 Mar 08; 361(9360):809-13. PMID: 12642046.
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    188. Matetzky S, Domingo M, Kar S, Noc M, Shah PK, Kaul S, Daar E, Cercek B. Acute myocardial infarction in human immunodeficiency virus-infected patients. Arch Intern Med. 2003 Feb 24; 163(4):457-60. PMID: 12588205.
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    189. Shah PK. Mechanisms of plaque vulnerability and rupture. J Am Coll Cardiol. 2003 Feb 19; 41(4 Suppl S):15S-22S. PMID: 12644336.
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    190. Qin M, Zeng Z, Zheng J, Shah PK, Schwartz SM, Adams LD, Sharifi BG. Suppression subtractive hybridization identifies distinctive expression markers for coronary and internal mammary arteries. Arterioscler Thromb Vasc Biol. 2003 Mar 01; 23(3):425-33. PMID: 12615697.
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    191. Shah PK. The calcium channel blocker lacidipine slows the progression of carotid atherosclerosis. Rev Cardiovasc Med. 2003; 4(3):191-2. PMID: 12949447.
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    192. Shah PK. Emerging non-statin LDL-lowering therapies for dyslipidemia and atherosclerosis. Rev Cardiovasc Med. 2003; 4(3):136-41. PMID: 12949442.
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    193. Uzui H, Harpf A, Liu M, Doherty TM, Shukla A, Chai NN, Tripathi PV, Jovinge S, Wilkin DJ, Asotra K, Shah PK, Rajavashisth TB. Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines. Circulation. 2002 Dec 10; 106(24):3024-30. PMID: 12473546.
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    194. Shah PK. Low-density lipoprotein lowering and atherosclerosis progression: does more mean less? Circulation. 2002 Oct 15; 106(16):2039-40. PMID: 12379568.
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    195. Finkelstein A, Makkar R, Doherty TM, Vegesna VR, Tripathi P, Liu M, Bergman J, Fishbein M, Hausleiter J, Takizawa K, Rukshin V, Shah PK, Rajavashisth TB. Increased expression of macrophage colony-stimulating factor after coronary artery balloon injury is inhibited by intracoronary brachytherapy. Circulation. 2002 May 21; 105(20):2411-5. PMID: 12021229.
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    196. Swissa M, Ohara T, Lee MH, Kaul S, Shah PK, Hayashi H, Chen PS, Karagueuzian HS. Sildenafil-nitric oxide donor combination promotes ventricular tachyarrhythmias in the swine right ventricle. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1787-92. PMID: 11959644.
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    197. Rukshin V, Shah PK, Cercek B, Finkelstein A, Tsang V, Kaul S. Comparative antithrombotic effects of magnesium sulfate and the platelet glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide in a canine model of stent thrombosis. Circulation. 2002 Apr 23; 105(16):1970-5. PMID: 11997285.
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    198. Dimayuga P, Cercek B, Oguchi S, Fredrikson GN, Yano J, Shah PK, Jovinge S, Nilsson J. Inhibitory effect on arterial injury-induced neointimal formation by adoptive B-cell transfer in Rag-1 knockout mice. Arterioscler Thromb Vasc Biol. 2002 Apr 01; 22(4):644-9. PMID: 11950704.
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    199. Shah PK. Chronic infections and atherosclerosis/thrombosis. Curr Atheroscler Rep. 2002 Mar; 4(2):113-9. PMID: 11822974.
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    200. Wallner K, Shah PK, Sharifi BG. Balloon catheterization induces arterial expression of new Tenascin-C isoform. Atherosclerosis. 2002 Mar; 161(1):75-83. PMID: 11882319.
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    201. Shah PK. Pathophysiology of coronary thrombosis: role of plaque rupture and plaque erosion. Prog Cardiovasc Dis. 2002 Mar-Apr; 44(5):357-68. PMID: 12024334.
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    202. Meisel SR, Xu XP, Edgington TS, Dimayuga P, Kaul S, Lee S, Fishbein MC, Cercek B, Shah PK. Differentiation of adherent human monocytes into macrophages markedly enhances tissue factor protein expression and procoagulant activity. Atherosclerosis. 2002 Mar; 161(1):35-43. PMID: 11882315.
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    203. Shah PK. Reduced tissue factor pathway inhibitor-1 after pharmacological thrombolysis: an epiphenomenon or potential culprit in rethrombosis? Circulation. 2002 Jan 22; 105(3):270-1. PMID: 11804975.
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    204. Price MJ, Shah PK. New strategies in managing and preventing atherosclerosis: focus on HDL. Rev Cardiovasc Med. 2002; 3(3):129-37. PMID: 12439437.
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    205. Shah PK, Kaul S, Nilsson J, Cercek B. Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part II. Circulation. 2001 Nov 13; 104(20):2498-502. PMID: 11705831.
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    206. Shah PK, Kaul S, Nilsson J, Cercek B. Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part I. Circulation. 2001 Nov 06; 104(19):2376-83. PMID: 11696481.
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    207. Shah PK, Yano J, Reyes O, Chyu KY, Kaul S, Bisgaier CL, Drake S, Cercek B. High-dose recombinant apolipoprotein A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilization. Circulation. 2001 Jun 26; 103(25):3047-50. PMID: 11425766.
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    208. Shah PK. Focus on HDL: a new treatment paradigm for athero-thrombotic vascular disease. Expert Opin Investig Drugs. 2000 Sep; 9(9):2139-46. PMID: 11060798.
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    209. Shah PK. Plaque disruption and thrombosis. Potential role of inflammation and infection. Cardiol Clin. 1999 May; 17(2):271-81. PMID: 10384826.
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