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Reza Ardehali

Title(s)Associate Professor-in-Residence, Medicine
SchoolMedicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
Phone58816
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    Collapse Research 
    Collapse Research Activities and Funding
    The role of pericytes in scar formation following stroke and myocardial infarction
    NIH/NINDS R01NS112256Mar 1, 2020 - Feb 28, 2025
    Role: Co-Principal Investigator
    Generation of mature human embryonic stem cell-derived left ventricular cardiomyocytes for transplantation in a large animal model
    NIH/NHLBI R01HL148714Jul 15, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Exploring heterogeneity of cardiac fibroblasts to reverse fibrosis
    NIH/NHLBI DP2HL127728Sep 30, 2014 - Sep 30, 2019
    Role: Principal Investigator
    Vascular Biology Training Grant
    NIH/NHLBI T32HL069766Apr 1, 2002 - Mar 31, 2023
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. In Vivo Clonal Analysis of Cardiomyocytes. Methods Mol Biol. 2021; 2158:243-256. Nguyen NB, Fernandez GE, Ding Y, Hsiai T, Ardehali R. PMID: 32857378.
      View in: PubMed   Mentions:    Fields:    
    2. Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress. Circulation. 2020 Jul 21; 142(3):275-291. He L, Nguyen NB, Ardehali R, Zhou B. PMID: 32687441.
      View in: PubMed   Mentions:    Fields:    
    3. Angiotensin Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use Among Outpatients Diagnosed With COVID-19. Am J Cardiol. 2020 Jul 12. Bae DJ, Tehrani DM, Rabadia SV, Frost M, Parikh RV, Calfon-Press M, Aksoy O, Umar S, Ardehali R, Rabbani A, Bokhoor P, Nsair A, Currier J, Tobis J, Fonarow GC, Dave R, Rafique AM. PMID: 32819683.
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    4. Heart Transplantation in the Early Phase of the COVID-19 Pandemic: A Single-Center Case Series. Clin Transplant. 2020 Jul 12; e14042. Hsu JJ, Al-Saffar F, Ardehali R, Baas AS, Carlson M, Cruz D, Deng M, Fan A, Fraschilla S, Gaynor P, Kamath M, Kubak BM, Schaenman J, Stimpson E, Vucicevic D, Ardehali A, Nsair A. PMID: 32654180.
      View in: PubMed   Mentions:    Fields:    
    5. Cardiac Fibrosis Is Associated With Decreased Circulating Levels of Full-Length CILP in Heart Failure. JACC Basic Transl Sci. 2020 May; 5(5):432-443. Park S, Ranjbarvaziri S, Zhao P, Ardehali R. PMID: 32478206.
      View in: PubMed   Mentions:
    6. Discovery of non-HLA antibodies associated with cardiac allograft rejection and development and validation of a non-HLA antigen multiplex panel: From bench to bedside. Am J Transplant. 2020 Mar 17. Butler CL, Hickey MJ, Jiang N, Zheng Y, Gjertson D, Zhang Q, Rao P, Fishbein GA, Cadeiras M, Deng MC, Banchs HL, Torre G, DeNofrio D, Eisen HJ, Kobashigawa J, Starling RC, Kfoury A, Van Bakel A, Ewald G, Balazs I, Baas AS, Cruz D, Ardehali R, Biniwale R, Kwon M, Ardehali A, Nsair A, Ray B, Reed EF. PMID: 32185871.
      View in: PubMed   Mentions:    Fields:    
    7. Electrically conductive nanomaterials for cardiac tissue engineering. Adv Drug Deliv Rev. 2019 04; 144:162-179. Ashtari K, Nazari H, Ko H, Tebon P, Akhshik M, Akbari M, Alhosseini SN, Mozafari M, Mehravi B, Soleimani M, Ardehali R, Ebrahimi Warkiani M, Ahadian S, Khademhosseini A. PMID: 31176755.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. Nanomedicine. 2019 07; 19:106-114. Nguyen NB, Chen CH, Zhang Y, Zhao P, Wu BM, Ardehali R. PMID: 31026512.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    9. Cardiovascular toxicities associated with immune checkpoint inhibitors. Cardiovasc Res. 2019 04 15; 115(5):854-868. Hu JR, Florido R, Lipson EJ, Naidoo J, Ardehali R, Tocchetti CG, Lyon AR, Padera RF, Johnson DB, Moslehi J. PMID: 30715219.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    10. Cardiac fibrosis: potential therapeutic targets. Transl Res. 2019 07; 209:121-137. Park S, Nguyen NB, Pezhouman A, Ardehali R. PMID: 30930180.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. Sendai virus based direct cardiac reprogramming: what lies ahead? Stem Cell Investig. 2018; 5:37. Engel JL, Ardehali R. PMID: 30498748.
      View in: PubMed   Mentions:
    12. Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. Circulation. 2018 09 18; 138(12):1224-1235. Park S, Ranjbarvaziri S, Lay FD, Zhao P, Miller MJ, Dhaliwal JS, Huertas-Vazquez A, Wu X, Qiao R, Soffer JM, Rau C, Wang Y, Mikkola HKA, Lusis AJ, Ardehali R. PMID: 29950403.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. Multiscale light-sheet for rapid imaging of cardiopulmonary system. JCI Insight. 2018 08 23; 3(16). Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, Fei P, Packard RRS, Hsiai TK. PMID: 30135307.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    14. Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities. Cell Stem Cell. 2018 Aug 02; 23(2):210-225.e6. McDonald AI, Shirali AS, Aragón R, Ma F, Hernandez G, Vaughn DA, Mack JJ, Lim TY, Sunshine H, Zhao P, Kalinichenko V, Hai T, Pelegrini M, Ardehali R, Iruela-Arispe ML. PMID: 30075129.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    15. Distal Left Main Coronary Artery Aneurysm Resection during 5-Vessel Coronary Artery Bypass Grafting. Tex Heart Inst J. 2018 04; 45(2):99-101. Villano NP, Kwon M, Ardehali R. PMID: 29844743.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Light-Sheet Imaging to Elucidate Cardiovascular Injury and Repair. Curr Cardiol Rep. 2018 03 24; 20(5):35. Ding Y, Lee J, Hsu JJ, Chang CC, Baek KI, Ranjbarvaziri S, Ardehali R, Packard RRS, Hsiai TK. PMID: 29574550.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    17. Clinical phenomapping and outcomes after heart transplantation. J Heart Lung Transplant. 2018 08; 37(8):956-966. Bakir M, Jackson NJ, Han SX, Bui A, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. PMID: 29802085.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. Direct Cardiac Reprogramming: Progress and Promise. Stem Cells Int. 2018; 2018:1435746. Engel JL, Ardehali R. PMID: 29731772.
      View in: PubMed   Mentions:
    19. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nat Commun. 2018 02 21; 9(1):754. Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R. PMID: 29467410.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    20. Cardiac manifestations of PRKAG2 mutation. BMC Med Genet. 2018 01 03; 19(1):1. Banankhah P, Fishbein GA, Dota A, Ardehali R. PMID: 29298659.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    21. Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. Circ Res. 2017 Jul 21; 121(3):e2-e8. Hill JA, Ardehali R, Clarke KT, Del Zoppo GJ, Eckhardt LL, Griendling KK, Libby P, Roden DM, Sadek HA, Seidman CE, Vaughan DE. PMID: 28652256.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts. Genesis. 2017 08; 55(8). Ranjbarvaziri S, Park S, Nguyen NB, Gilmore WB, Zhao P, Ardehali R. PMID: 28589709.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. Biomarkers of Human Pluripotent Stem Cell-Derived Cardiac Lineages. Trends Mol Med. 2017 07; 23(7):651-668. Skelton RJP, Kamp TJ, Elliott DA, Ardehali R. PMID: 28576602.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Giant cell myocarditis masquerading as orbital myositis with a rapid, fulminant course necessitating mechanical support and heart transplantation. ESC Heart Fail. 2017 Aug; 4(3):371-375. Garg V, Tan W, Ardehali R, Shah J, Huynh T, Aksoy O. PMID: 28772042.
      View in: PubMed   Mentions: 1     Fields:    
    25. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67. Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    26. Cardiac Light-Sheet Fluorescent Microscopy for Multi-Scale and Rapid Imaging of Architecture and Function. Sci Rep. 2016 Mar 03; 6:22489. Fei P, Lee J, Packard RR, Sereti KI, Xu H, Ma J, Ding Y, Kang H, Chen H, Sung K, Kulkarni R, Ardehali R, Kuo CC, Xu X, Ho CM, Hsiai TK. PMID: 26935567.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    27. CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. Stem Cell Reports. 2016 Jan 12; 6(1):95-108. Skelton RJ, Brady B, Khoja S, Sahoo D, Engel J, Arasaratnam D, Saleh KK, Abilez OJ, Zhao P, Stanley EG, Elefanty AG, Kwon M, Elliott DA, Ardehali R. PMID: 26771355.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors. Stem Cells Transl Med. 2016 Jan; 5(1):67-74. Skelton RJ, Khoja S, Almeida S, Rapacchi S, Han F, Engel J, Zhao P, Hu P, Stanley EG, Elefanty AG, Kwon M, Elliott DA, Ardehali R. PMID: 26582908.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    29. Translational aspects of cardiac cell therapy. J Cell Mol Med. 2015 Aug; 19(8):1757-72. Chen CH, Sereti KI, Wu BM, Ardehali R. PMID: 26119413.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    30. Arrhythmia in stem cell transplantation. Card Electrophysiol Clin. 2015 Jun; 7(2):357-70. Almeida SO, Skelton RJ, Adigopula S, Ardehali R. PMID: 26002399.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    31. COCATS 4 Task Force 12: Training in Heart Failure. J Am Coll Cardiol. 2015 May 05; 65(17):1866-76. Jessup M, Ardehali R, Konstam MA, Manno BV, Mathier MA, McPherson JA, Sweitzer NK. PMID: 25777644.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Insights into aortic sclerosis and its relationship with coronary artery disease. J Am Heart Assoc. 2014 Sep 05; 3(5):e001111. Milin AC, Vorobiof G, Aksoy O, Ardehali R. PMID: 25193296.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation. Circ Res. 2014 Sep 12; 115(7):625-35. Ali SR, Ranjbarvaziri S, Talkhabi M, Zhao P, Subat A, Hojjat A, Kamran P, Müller AM, Volz KS, Tang Z, Red-Horse K, Ardehali R. PMID: 25037571.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    34. Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24):8850-5. Ali SR, Hippenmeyer S, Saadat LV, Luo L, Weissman IL, Ardehali R. PMID: 24876275.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    35. SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development. Stem Cell Res. 2014 Jul; 13(1):172-9. Skelton RJ, Costa M, Anderson DJ, Bruveris F, Finnin BW, Koutsis K, Arasaratnam D, White AJ, Rafii A, Ng ES, Elefanty AG, Stanley EG, Pouton CW, Haynes JM, Ardehali R, Davis RP, Mummery CL, Elliott DA. PMID: 24968096.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    36. c-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface. Dev Cell. 2013 Nov 25; 27(4):373-86. Ueno M, Lee LK, Chhabra A, Kim YJ, Sasidharan R, Van Handel B, Wang Y, Kamata M, Kamran P, Sereti KI, Ardehali R, Jiang M, Mikkola HK. PMID: 24286824.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    37. Parabiosis in mice: a detailed protocol. J Vis Exp. 2013 Oct 06; (80). Kamran P, Sereti KI, Zhao P, Ali SR, Weissman IL, Ardehali R. PMID: 24145664.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    38. Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3405-10. Ardehali R, Ali SR, Inlay MA, Abilez OJ, Chen MQ, Blauwkamp TA, Yazawa M, Gong Y, Nusse R, Drukker M, Weissman IL. PMID: 23391730.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    39. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol. 2012 May 27; 30(6):531-42. Drukker M, Tang C, Ardehali R, Rinkevich Y, Seita J, Lee AS, Mosley AR, Weissman IL, Soen Y. PMID: 22634564.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    40. The effect of angiotensin-converting enzyme inhibitors and statins on the progression of aortic sclerosis and mortality. J Heart Valve Dis. 2012 May; 21(3):337-43. Ardehali R, Leeper NJ, Wilson AM, Heidenreich PA. PMID: 22808835.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    41. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nat Commun. 2012; 3:1070. Blauwkamp TA, Nigam S, Ardehali R, Weissman IL, Nusse R. PMID: 22990866.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    42. Enhanced survival of pluripotent stem cells under stressful conditions. Cell Cycle. 2011 Aug 15; 10(16):2610-1. Ardehali R, Ali SR, Inlay MA, Mosley AR, Weissman IL. PMID: 21791974.
      View in: PubMed   Mentions:    Fields:    
    43. An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol. 2011 Aug 14; 29(9):829-34. Tang C, Lee AS, Volkmer JP, Sahoo D, Nag D, Mosley AR, Inlay MA, Ardehali R, Chavez SL, Pera RR, Behr B, Wu JC, Weissman IL, Drukker M. PMID: 21841799.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    44. Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3282-7. Ardehali R, Inlay MA, Ali SR, Tang C, Drukker M, Weissman IL. PMID: 21300885.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    45. Isolated disease of the proximal left anterior descending artery comparing the effectiveness of percutaneous coronary interventions and coronary artery bypass surgery. JACC Cardiovasc Interv. 2008 Oct; 1(5):483-91. Kapoor JR, Gienger AL, Ardehali R, Varghese R, Perez MV, Sundaram V, McDonald KM, Owens DK, Hlatky MA, Bravata DM. PMID: 19463349.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    46. Systematic review: the comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery. Ann Intern Med. 2007 Nov 20; 147(10):703-16. Bravata DM, Gienger AL, McDonald KM, Sundaram V, Perez MV, Varghese R, Kapoor JR, Ardehali R, Owens DK, Hlatky MA. PMID: 17938385.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    47. Statin use in patients with extremely low low-density lipoprotein levels is associated with improved survival. Circulation. 2007 Aug 07; 116(6):613-8. Leeper NJ, Ardehali R, deGoma EM, Heidenreich PA. PMID: 17664373.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    48. Screening patients for subclinical atherosclerosis with non-contrast cardiac CT. Atherosclerosis. 2007 Jun; 192(2):235-42. Ardehali R, Nasir K, Kolandaivelu A, Budoff MJ, Blumenthal RS. PMID: 17467714.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Successful removal of a paradoxical coronary embolus using an aspiration catheter. Nat Clin Pract Cardiovasc Med. 2006 Nov; 3(11):633-6. Wilson AM, Ardehali R, Brinton TJ, Yeung AC, Vagelos R. PMID: 17063168.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. A long and bumpy road. Am J Med. 2006 Nov; 119(11):923-6. Ardehali R, Reed AS, Owens C, Meininger GR, Conte JV, Hare JM. PMID: 17071156.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Recurrent spontaneous coronary artery dissection with transient left ventricular systolic dysfunction. Int J Cardiol. 2007 Mar 20; 116(2):e48-50. Ardehali R, Brinton TJ, Wilson AM, Gradman M, Vagelos RH, Lee DP. PMID: 16930750.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Cutting balloon inflation for drug-eluting stent underexpansion due to unrecognized coronary arterial calcification. Cardiovasc Revasc Med. 2006 Jul-Sep; 7(3):185-8. Wilson A, Ardehali R, Brinton TJ, Yeung AC, Lee DP. PMID: 16945827.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    53. Aspirin and clopidogrel resistance. Mayo Clin Proc. 2006 Apr; 81(4):518-26. Michos ED, Ardehali R, Blumenthal RS, Lange RA, Ardehali H. PMID: 16610572.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    54. Percutaneous valve replacement: current state and future prospects. Ann Thorac Surg. 2004 Dec; 78(6):2199-206. Lutter G, Ardehali R, Cremer J, Bonhoeffer P. PMID: 15561078.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    55. The inhibitory activity of serum to prevent bacterial adhesion is mainly due to apo-transferrin. J Biomed Mater Res A. 2003 Jul 01; 66(1):21-8. Ardehali R, Shi L, Janatova J, Mohammad SF, Burns GL. PMID: 12833427.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    56. The effect of apo-transferrin on bacterial adhesion to biomaterials. Artif Organs. 2002 Jun; 26(6):512-20. Ardehali R, Shi L, Janatova J, Mohammad SF, Burns GL. PMID: 12072107.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    57. 111Indium labeling of microorganisms to facilitate the investigation of bacterial adhesion. J Biomed Mater Res. 1993 Feb; 27(2):269-75. Ardehali R, Mohammad SF. PMID: 8436584.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
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