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(Pro)renin receptor signaling in hypothalamic tyrosine hydroxylase neurons is required for obesity-associated glucose metabolic impairment. JCI Insight. 2024 Feb 13; 9(6).
Pan S, A C Souza L, Worker CJ, Reyes Mendez ME, Gayban AJB, Cooper SG, Sanchez Solano A, Bergman RN, Stefanovski D, Morton GJ, Schwartz MW, Feng Earley Y. PMID: 38349753.
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Translation:
AnimalsCells
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Pancreatic β cell function versus insulin resistance: application of the hyperbolic law of glucose tolerance. J Clin Invest. 2024 Feb 01; 134(3).
Bergman RN. PMID: 38299589; PMCID: PMC10836807.
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HumansCells
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Life-cycle impact assessment of hardwood forest resources in the eastern United States. Sci Total Environ. 2024 Jan 20; 909:168458.
Zhao J, Smith W, Wang J, Zhang X, Bergman R. PMID: 37977370.
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Methods for estimating insulin resistance from untargeted metabolomics data. Metabolomics. 2023 08 09; 19(8):72.
Hsu FC, Palmer ND, Chen SH, Ng MCY, Goodarzi MO, Rotter JI, Wagenknecht LE, Bancks MP, Bergman RN, Bowden DW. PMID: 37558891; PMCID: PMC10412652.
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Humans
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. Nat Genet. 2023 06; 55(6):973-983.
Williamson A, Norris DM, Yin X, Broadaway KA, Moxley AH, Vadlamudi S, Wilson EP, Jackson AU, Ahuja V, Andersen MK, Arzumanyan Z, Bonnycastle LL, Bornstein SR, Bretschneider MP, Buchanan TA, Chang YC, Chuang LM, Chung RH, Clausen TD, Damm P, Delgado GE, de Mello VD, Dupuis J, Dwivedi OP, Erdos MR, Fernandes Silva L, Frayling TM, Gieger C, Goodarzi MO, Guo X, Gustafsson S, Hakaste L, Hammar U, Hatem G, Herrmann S, Højlund K, Horn K, Hsueh WA, Hung YJ, Hwu CM, Jonsson A, Kårhus LL, Kleber ME, Kovacs P, Lakka TA, Lauzon M, Lee IT, Lindgren CM, Lindström J, Linneberg A, Liu CT, Luan J, Aly DM, Mathiesen E, Moissl AP, Morris AP, Narisu N, Perakakis N, Peters A, Prasad RB, Rodionov RN, Roll K, Rundsten CF, Sarnowski C, Savonen K, Scholz M, Sharma S, Stinson SE, Suleman S, Tan J, Taylor KD, Uusitupa M, Vistisen D, Witte DR, Walther R, Wu P, Xiang AH, Zethelius B, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), Ahlqvist E, Bergman RN, Chen YI, Collins FS, Fall T, Florez JC, Fritsche A, Grallert H, Groop L, Hansen T, Koistinen HA, Komulainen P, Laakso M, Lind L, Loeffler M, März W, Meigs JB, Raffel LJ, Rauramaa R, Rotter JI, Schwarz PEH, Stumvoll M, Sundström J, Tönjes A, Tuomi T, Tuomilehto J, Wagner R, Barroso I, Walker M, Grarup N, Boehnke M, Wareham NJ, Mohlke KL, Wheeler E, O'Rahilly S, Fazakerley DJ, Langenberg C. PMID: 37291194; PMCID: PMC7614755.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Dapagliflozin prevents abdominal visceral and subcutaneous adipose tissue dysfunction in the insulin-resistant canine model. Obesity (Silver Spring). 2023 07; 31(7):1798-1811.
Kabir M, Bergman RN, Porter J, Stefanovski D, Paszkiewicz RL, Piccinini F, Woolcott OO, Yang H, Gopaul VS, Stiles L, Kolka CM. PMID: 37221655; PMCID: PMC10981466.
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PubMed Mentions:
1 Fields:
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Animals
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Experiences as Editor of Obesity. Obesity (Silver Spring). 2022 11; 30(11):2107-2108.
Bergman RN. PMID: 36173251.
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Humans
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Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV). J Eur Acad Dermatol Venereol. 2022 Oct; 36(10):1689-1704.
Borradori L, Van Beek N, Feliciani C, Tedbirt B, Antiga E, Bergman R, Böckle BC, Caproni M, Caux F, Chandran NS, Cianchini G, Daneshpazhooh M, De D, Didona D, Di Zenzo GM, Dmochowski M, Drenovska K, Ehrchen J, Goebeler M, Groves R, Günther C, Horvath B, Hertl M, Hofmann S, Ioannides D, Itzlinger-Monshi B, Jedlicková J, Kowalewski C, Kridin K, Lim YL, Marinovic B, Marzano AV, Mascaro JM, Meijer JM, Murrell D, Patsatsi K, Pincelli C, Prost C, Rappersberger K, Sárdy M, Setterfield J, Shahid M, Sprecher E, Tasanen K, Uzun S, Vassileva S, Vestergaard K, Vorobyev A, Vujic I, Wang G, Wozniak K, Yayli S, Zambruno G, Zillikens D, Schmidt E, Joly P. PMID: 35766904.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Measures of glucose homeostasis during and after duodenal exclusion using a duodenal-jejunal bypass liner in a normoglycemic, nonobese canine model. Surg Obes Relat Dis. 2022 06; 18(6):694-702.
Paszkiewicz RL, Burch MA, Asare Bediako I, Mkrtchyan H, Piccinini F, Ader M, Bresee C, Bergman RN. PMID: 35361540; PMCID: PMC10013877.
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HumansAnimals
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The Physiology of Insulin Clearance. Int J Mol Sci. 2022 Feb 05; 23(3).
Bergman RN, Kabir M, Ader M. PMID: 35163746; PMCID: PMC8836929.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Cannabinoid receptor type 2 is upregulated in synovium following joint injury and mediates anti-inflammatory effects in synovial fibroblasts and macrophages. Osteoarthritis Cartilage. 2021 12; 29(12):1720-1731.
Rzeczycki P, Rasner C, Lammlin L, Junginger L, Goldman S, Bergman R, Redding S, Knights AJ, Elliott M, Maerz T. PMID: 34537380; PMCID: PMC8883578.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Hyperinsulinemic Compensation for Insulin Resistance Occurs Independent of Elevated Glycemia in Male Dogs. Endocrinology. 2021 09 01; 162(9).
Ader M, Bergman RN. PMID: 34132779; PMCID: PMC8282122.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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The trans-ancestral genomic architecture of glycemic traits. Nat Genet. 2021 06; 53(6):840-860.
Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lifelines Cohort Study, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I, O'Connell JR, Oldehinkel AJ, Ong KK, et al. PMID: 34059833; PMCID: PMC7610958.
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201 Fields:
Translation:
Humans
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Response to Comment on Piccinini and Bergman The Measurement of Insulin Clearance. Diabetes Care 2020;43:2296-2302. Diabetes Care. 2021 05; 44(5):e100-e101.
Bergman RN, Piccinini F. PMID: 33972319; PMCID: PMC8132327.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639. Int J Mol Sci. 2021 Apr 22; 22(9).
Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M. PMID: 33922401; PMCID: PMC8122324.
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PubMed Mentions: Fields:
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Voices: Insulin and beyond. Cell Metab. 2021 04 06; 33(4):692-699.
Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, Saltiel AR, Corkey BE, Atkinson MA. PMID: 33826910.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Origins and History of the Minimal Model of Glucose Regulation. Front Endocrinol (Lausanne). 2020; 11:583016.
Bergman RN. PMID: 33658981; PMCID: PMC7917251.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Response to Zubieta-Calleja et al., Re: "Mortality Attributed to COVID-19 in High-Altitude Populations". High Alt Med Biol. 2021 03; 22(1):109.
Woolcott OO, Bergman RN. PMID: 33567229.
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HumansCells
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Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021 Feb 08; 12(1):995.
Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC). PMID: 33558525; PMCID: PMC7870968.
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2 Fields:
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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021 01 05; 12(1):24.
Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC). PMID: 33402679; PMCID: PMC7785747.
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PubMed Mentions:
64 Fields:
Translation:
Humans
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A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided. Int J Mol Sci. 2020 Sep 10; 21(18).
Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M. PMID: 32927872; PMCID: PMC7554772.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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The Measurement of Insulin Clearance. Diabetes Care. 2020 09; 43(9):2296-2302.
Piccinini F, Bergman RN. PMID: 32910777; PMCID: PMC7440908.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Updated S2K guidelines on the management of pemphigus vulgaris and foliaceus initiated by the european academy of dermatology and venereology (EADV). J Eur Acad Dermatol Venereol. 2020 Sep; 34(9):1900-1913.
Joly P, Horvath B, Patsatsi ?, Uzun S, Bech R, Beissert S, Bergman R, Bernard P, Borradori L, Caproni M, Caux F, Cianchini G, Daneshpazhooh M, De D, Dmochowski M, Drenovska K, Ehrchen J, Feliciani C, Goebeler M, Groves R, Guenther C, Hofmann S, Ioannides D, Kowalewski C, Ludwig R, Lim YL, Marinovic B, Marzano AV, Mascaró JM, Mimouni D, Murrell DF, Pincelli C, Squarcioni CP, Sárdy M, Setterfield J, Sprecher E, Vassileva S, Wozniak K, Yayli S, Zambruno G, Zillikens D, Hertl M, Schmidt E. PMID: 32830877.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Mortality Attributed to COVID-19 in High-Altitude Populations. High Alt Med Biol. 2020 12; 21(4):409-416.
Woolcott OO, Bergman RN. PMID: 32815745.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity. J Clin Invest. 2020 05 01; 130(5):2209-2219.
O'Mara AE, Johnson JW, Linderman JD, Brychta RJ, McGehee S, Fletcher LA, Fink YA, Kapuria D, Cassimatis TM, Kelsey N, Cero C, Sater ZA, Piccinini F, Baskin AS, Leitner BP, Cai H, Millo CM, Dieckmann W, Walter M, Javitt NB, Rotman Y, Walter PJ, Ader M, Bergman RN, Herscovitch P, Chen KY, Cypess AM. PMID: 31961826; PMCID: PMC7190915.
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PubMed Mentions:
138 Fields:
Translation:
HumansCTClinical Trials
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Impact of sleep deprivation and high-fat feeding on insulin sensitivity and beta cell function in dogs. Diabetologia. 2020 04; 63(4):875-884.
Brouwer A, Asare Bediako I, Paszkiewicz RL, Kolka CM, Bergman RN, Broussard JL. PMID: 32016566; PMCID: PMC7304935.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Defining cutoffs to diagnose obesity using the relative fat mass (RFM): Association with mortality in NHANES 1999-2014. Int J Obes (Lond). 2020 06; 44(6):1301-1310.
Woolcott OO, Bergman RN. PMID: 31911664.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Relative Fat Mass as an estimator of whole-body fat percentage among children and adolescents: A cross-sectional study using NHANES. Sci Rep. 2019 10 24; 9(1):15279.
Woolcott OO, Bergman RN. PMID: 31649287; PMCID: PMC6813362.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes 2019;68:1709-1716. Diabetes. 2019 Dec; 68(12):2350.
Bergman RN, Piccinini F, Kabir M, Kolka CM, Ader M. PMID: 31597638; PMCID: PMC6969554.
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PubMed Mentions: Fields:
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Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes. 2019 09; 68(9):1709-1716.
Bergman RN, Piccinini F, Kabir M, Kolka CM, Ader M. PMID: 31431441; PMCID: PMC6702636.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs. Am J Physiol Endocrinol Metab. 2019 09 01; 317(3):E535-E547.
Iyer MS, Paszkiewicz RL, Bergman RN, Richey JM, Woolcott OO, Asare-Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Clegg DJ, Kabir M. PMID: 31237449; PMCID: PMC6766608.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Novel aspects of the role of the liver in carbohydrate metabolism. Metabolism. 2019 10; 99:119-125.
Bergman RN, Piccinini F, Kabir M, Ader M. PMID: 31158368; PMCID: PMC7216693.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Glucoregulatory responses to hypothalamic preoptic area cooling. Brain Res. 2019 05 01; 1710:136-145.
Muta K, Matsen ME, Acharya NK, Stefanovski D, Bergman RN, Schwartz MW, Morton GJ. PMID: 30610874; PMCID: PMC6532776.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain. Diabetes. 2019 03; 68(3):654-664.
Scarlett JM, Muta K, Brown JM, Rojas JM, Matsen ME, Acharya NK, Secher A, Ingvorsen C, Jorgensen R, Høeg-Jensen T, Stefanovski D, Bergman RN, Piccinini F, Kaiyala KJ, Shiota M, Morton GJ, Schwartz MW. PMID: 30523024; PMCID: PMC6385755.
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28 Fields:
Translation:
HumansAnimals
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Dissection of hepatic versus extra-hepatic insulin clearance: Ethnic differences in childhood. Diabetes Obes Metab. 2018 12; 20(12):2869-2875.
Piccinini F, Polidori DC, Gower BA, Fernandez JR, Bergman RN. PMID: 30019375; PMCID: PMC6482814.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Relative fat mass (RFM) as a new estimator of whole-body fat percentage ─ A cross-sectional study in American adult individuals. Sci Rep. 2018 Jul 20; 8(1):10980.
Woolcott OO, Bergman RN. PMID: 30030479; PMCID: PMC6054651.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis. J Diabetes. 2018 Oct; 10(10):778-783.
Bergman RN, Piccinini F, Asare Bediako I, Kabir M, Kolka C, Polidori D, Ader M. PMID: 29961982; PMCID: PMC7219598.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin. Diabetes. 2018 08; 67(8):1495-1503.
Asare-Bediako I, Paszkiewicz RL, Kim SP, Woolcott OO, Kolka CM, Burch MA, Kabir M, Bergman RN. PMID: 29752425; PMCID: PMC6054441.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS). J Clin Endocrinol Metab. 2018 05 01; 103(5):1877-1888.
Palmer ND, Okut H, Hsu FC, Ng MCY, Chen YI, Goodarzi MO, Taylor KD, Norris JM, Lorenzo C, Rotter JI, Bergman RN, Langefeld CD, Wagenknecht LE, Bowden DW. PMID: 29546329; PMCID: PMC6456957.
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12 Fields:
Translation:
Humans
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Assessment of hepatic insulin extraction from in vivo surrogate methods of insulin clearance measurement. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E605-E612.
Asare-Bediako I, Paszkiewicz RL, Kim SP, Woolcott OO, Kolka CM, Burch M, Kabir M, Piccinini F, Bergman RN. PMID: 29509434; PMCID: PMC6230713.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2018 01 23; 5:180002.
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stancáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI. PMID: 29360107; PMCID: PMC5779067.
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1 Fields:
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2017 12 19; 4:170179.
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stancáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI. PMID: 29257133; PMCID: PMC5735917.
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16 Fields:
Translation:
Humans
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Insulin Access to Skeletal Muscle is Preserved in Obesity Induced by Polyunsaturated Diet. Obesity (Silver Spring). 2018 01; 26(1):119-125.
Broussard JL, Bergman RN, Bediako IA, Paszkiewicz RL, Iyer MS, Kolka CM. PMID: 29193779; PMCID: PMC5739979.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes. Sci Rep. 2017 08 23; 7(1):9234.
Schüler R, Osterhoff MA, Frahnow T, Möhlig M, Spranger J, Stefanovski D, Bergman RN, Xu L, Seltmann AC, Kabisch S, Hornemann S, Kruse M, Pfeiffer AFH. PMID: 28835639; PMCID: PMC5569105.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017 Aug; 13(8):e1006972.
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD, Hayes JE, Cornelis M, Kutalik Z, Lim E, Luan J, Huffman JE, Zhang W, Zhao W, Griffin PJ, Haller T, Ahmad S, Marques-Vidal PM, Bien S, Yengo L, Teumer A, Smith AV, Kumari M, Harder MN, Justesen JM, Kleber ME, Hollensted M, Lohman K, Rivera NV, Whitfield JB, Zhao JH, Stringham HM, Lyytikäinen LP, Huppertz C, Willemsen G, Peyrot WJ, Wu Y, Kristiansson K, Demirkan A, Fornage M, Hassinen M, Bielak LF, Cadby G, Tanaka T, Mägi R, van der Most PJ, Jackson AU, Bragg-Gresham JL, Vitart V, Marten J, Navarro P, Bellis C, Pasko D, Johansson Å, Snitker S, Cheng YC, Eriksson J, Lim U, Aadahl M, Adair LS, Amin N, Balkau B, Auvinen J, Beilby J, Bergman RN, Bergmann S, Bertoni AG, Blangero J, Bonnefond A, Bonnycastle LL, Borja JB, Brage S, Busonero F, Buyske S, Campbell H, Chines PS, Collins FS, Corre T, Smith GD, Delgado GE, Dueker N, Dörr M, Ebeling T, Eiriksdottir G, Esko T, Faul JD, Fu M, Færch K, Gieger C, Gläser S, Gong J, Gordon-Larsen P, Grallert H, Grammer TB, Grarup N, van Grootheest G, Harald K, Hastie ND, Havulinna AS, Hernandez D, Hindorff L, Hocking LJ, Holmens OL, Holzapfel C, Hottenga JJ, Huang J, Huang T, Hui J, Huth C, Hutri-Kähönen N, James AL, Jansson JO, Jhun MA, Juonala M, Kinnunen L, Koistinen HA, Kolcic I, Komulainen P, Kuusisto J, Kvaløy K, Kähönen M, Lakka TA, Launer LJ, Lehne B, Lindgren CM, Lorentzon M, Luben R, Marre M, Milaneschi Y, Monda KL, Montgomery GW, De Moor MHM, Mulas A, Müller-Nurasyid M, Musk AW, Männikkö R, Männistö S, Narisu N, Nauck M, Nettleton JA, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Paternoster L, Perez J, Perola M, Peters A, Peters U, Peyser PA, Prokopenko I, Puolijoki H, Raitakari OT, Rankinen T, Rasmussen-Torvik LJ, Rawal R, Ridker PM, Rose LM, Rudan I, Sarti C, Sarzynski MA, Savonen K, Scott WR, Sanna S, Shuldiner AR, Sidney S, Silbernagel G, Smith BH, Smith JA, Snieder H, Stancáková A, Sternfeld B, Swift AJ, Tammelin T, Tan ST, Thorand B, Thuillier D, Vandenput L, Vestergaard H, van Vliet-Ostaptchouk JV, Vohl MC, Völker U, Waeber G, Walker M, Wild S, Wong A, Wright AF, Zillikens MC, Zubair N, Haiman CA, Lemarchand L, Gyllensten U, Ohlsson C, Hofman A, Rivadeneira F, Uitterlinden AG, Pérusse L, Wilson JF, Hayward C, Polasek O, Cucca F, Hveem K, Hartman CA, Tönjes A, Bandinelli S, Palmer LJ, Kardia SLR, Rauramaa R, Sørensen TIA, Tuomilehto J, Salomaa V, Penninx BWJH, de Geus EJC, Boomsma DI, Lehtimäki T, Mangino M, Laakso M, Bouchard C, Martin NG, Kuh D, Liu Y, Linneberg A, März W, Strauch K, Kivimäki M, Harris TB, Gudnason V, Völzke H, Qi L, Järvelin MR, Chambers JC, Kooner JS, Froguel P, Kooperberg C, Vollenweider P, Hallmans G, Hansen T, Pedersen O, Metspalu A, Wareham NJ, Langenberg C, Weir DR, Porteous DJ, Boerwinkle E, Chasman DI, CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium, Abecasis GR, Barroso I, McCarthy MI, Frayling TM, O'Connell JR, van Duijn CM, Boehnke M, Heid IM, Mohlke KL, Strachan DP, Fox CS, Liu CT, Hirschhorn JN, Klein RJ, Johnson AD, Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpeläinen TO. PMID: 28832619; PMCID: PMC5567921.
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6 Fields:
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Hepatic but Not Extrahepatic Insulin Clearance Is Lower in African American Than in European American Women. Diabetes. 2017 10; 66(10):2564-2570.
Piccinini F, Polidori DC, Gower BA, Bergman RN. PMID: 28710139; PMCID: PMC5606316.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Indirect Regulation of Endogenous Glucose Production by Insulin: The Single Gateway Hypothesis Revisited. Diabetes. 2017 07; 66(7):1742-1747.
Bergman RN, Iyer MS. PMID: 28637826.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. 2017 11; 66(11):2888-2902.
Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, Thorleifsson G, Qi L, Van Zuydam NR, Mahajan A, Chen H, Almgren P, Voight BF, Grallert H, Müller-Nurasyid M, Ried JS, Rayner NW, Robertson N, Karssen LC, van Leeuwen EM, Willems SM, Fuchsberger C, Kwan P, Teslovich TM, Chanda P, Li M, Lu Y, Dina C, Thuillier D, Yengo L, Jiang L, Sparso T, Kestler HA, Chheda H, Eisele L, Gustafsson S, Frånberg M, Strawbridge RJ, Benediktsson R, Hreidarsson AB, Kong A, Sigurðsson G, Kerrison ND, Luan J, Liang L, Meitinger T, Roden M, Thorand B, Esko T, Mihailov E, Fox C, Liu CT, Rybin D, Isomaa B, Lyssenko V, Tuomi T, Couper DJ, Pankow JS, Grarup N, Have CT, Jørgensen ME, Jørgensen T, Linneberg A, Cornelis MC, van Dam RM, Hunter DJ, Kraft P, Sun Q, Edkins S, Owen KR, Perry JRB, Wood AR, Zeggini E, Tajes-Fernandes J, Abecasis GR, Bonnycastle LL, Chines PS, Stringham HM, Koistinen HA, Kinnunen L, Sennblad B, Mühleisen TW, Nöthen MM, Pechlivanis S, Baldassarre D, Gertow K, Humphries SE, Tremoli E, Klopp N, Meyer J, Steinbach G, Wennauer R, Eriksson JG, M?nnistö S, Peltonen L, Tikkanen E, Charpentier G, Eury E, Lobbens S, Gigante B, Leander K, McLeod O, Bottinger EP, Gottesman O, Ruderfer D, Blüher M, Kovacs P, Tonjes A, Maruthur NM, Scapoli C, Erbel R, Jöckel KH, Moebus S, de Faire U, Hamsten A, Stumvoll M, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, Ripatti S, Salomaa V, Pedersen NL, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, Hansen T, Pedersen O, Barroso I, Lannfelt L, Ingelsson E, Lind L, Lindgren CM, Cauchi S, Froguel P, Loos RJF, Balkau B, Boeing H, Franks PW, Barricarte Gurrea A, Palli D, van der Schouw YT, Altshuler D, Groop LC, Langenberg C, Wareham NJ, Sijbrands E, van Duijn CM, Florez JC, Meigs JB, Boerwinkle E, Gieger C, Strauch K, Metspalu A, Morris AD, Palmer CNA, Hu FB, Thorsteinsdottir U, Stefansson K, Dupuis J, Morris AP, Boehnke M, McCarthy MI, Prokopenko I, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. PMID: 28566273; PMCID: PMC5652602.
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346 Fields:
Translation:
Humans
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A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Diabetes. 2017 08; 66(8):2296-2309.
Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, Kobes S, Deelen J, Boquete-Vilarino L, Paananen J, Stancáková A, Boomsma DI, de Geus EJC, Eekhoff EMW, Fritsche A, Kramer M, Nijpels G, Simonis-Bik A, van Haeften TW, Mahajan A, Boehnke M, Bergman RN, Tuomilehto J, Collins FS, Mohlke KL, Banasik K, Groves CJ, McCarthy MI, Diabetes Research on Patient Stratification (DIRECT), Pearson ER, Natali A, Mari A, Buchanan TA, Taylor KD, Xiang AH, Gjesing AP, Grarup N, Eiberg H, Pedersen O, Chen YD, Laakso M, Norris JM, Smith U, Wagenknecht LE, Baier L, Bowden DW, Hansen T, Walker M, Watanabe RM, 't Hart LM, Hanson RL, Frayling TM. PMID: 28490609; PMCID: PMC5521867.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017 Apr; 13(4):e1006528.
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD, Hayes JE, Cornelis M, Kutalik Z, Lim E, Luan J, Huffman JE, Zhang W, Zhao W, Griffin PJ, Haller T, Ahmad S, Marques-Vidal PM, Bien S, Yengo L, Teumer A, Smith AV, Kumari M, Harder MN, Justesen JM, Kleber ME, Hollensted M, Lohman K, Rivera NV, Whitfield JB, Zhao JH, Stringham HM, Lyytikäinen LP, Huppertz C, Willemsen G, Peyrot WJ, Wu Y, Kristiansson K, Demirkan A, Fornage M, Hassinen M, Bielak LF, Cadby G, Tanaka T, Mägi R, van der Most PJ, Jackson AU, Bragg-Gresham JL, Vitart V, Marten J, Navarro P, Bellis C, Pasko D, Johansson Å, Snitker S, Cheng YC, Eriksson J, Lim U, Aadahl M, Adair LS, Amin N, Balkau B, Auvinen J, Beilby J, Bergman RN, Bergmann S, Bertoni AG, Blangero J, Bonnefond A, Bonnycastle LL, Borja JB, Brage S, Busonero F, Buyske S, Campbell H, Chines PS, Collins FS, Corre T, Smith GD, Delgado GE, Dueker N, Dörr M, Ebeling T, Eiriksdottir G, Esko T, Faul JD, Fu M, Færch K, Gieger C, Gläser S, Gong J, Gordon-Larsen P, Grallert H, Grammer TB, Grarup N, van Grootheest G, Harald K, Hastie ND, Havulinna AS, Hernandez D, Hindorff L, Hocking LJ, Holmens OL, Holzapfel C, Hottenga JJ, Huang J, Huang T, Hui J, Huth C, Hutri-Kähönen N, James AL, Jansson JO, Jhun MA, Juonala M, Kinnunen L, Koistinen HA, Kolcic I, Komulainen P, Kuusisto J, Kvaløy K, Kähönen M, Lakka TA, Launer LJ, Lehne B, Lindgren CM, Lorentzon M, Luben R, Marre M, Milaneschi Y, Monda KL, Montgomery GW, De Moor MHM, Mulas A, Müller-Nurasyid M, Musk AW, Männikkö R, Männistö S, Narisu N, Nauck M, Nettleton JA, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Paternoster L, Perez J, Perola M, Peters A, Peters U, Peyser PA, Prokopenko I, Puolijoki H, Raitakari OT, Rankinen T, Rasmussen-Torvik LJ, Rawal R, Ridker PM, Rose LM, Rudan I, Sarti C, Sarzynski MA, Savonen K, Scott WR, Sanna S, Shuldiner AR, Sidney S, Silbernagel G, Smith BH, Smith JA, Snieder H, Stancáková A, Sternfeld B, Swift AJ, Tammelin T, Tan ST, Thorand B, Thuillier D, Vandenput L, Vestergaard H, van Vliet-Ostaptchouk JV, Vohl MC, Völker U, Waeber G, Walker M, Wild S, Wong A, Wright AF, Zillikens MC, Zubair N, Haiman CA, Lemarchand L, Gyllensten U, Ohlsson C, Hofman A, Rivadeneira F, Uitterlinden AG, Pérusse L, Wilson JF, Hayward C, Polasek O, Cucca F, Hveem K, Hartman CA, Tönjes A, Bandinelli S, Palmer LJ, Kardia SLR, Rauramaa R, Sørensen TIA, Tuomilehto J, Salomaa V, Penninx BWJH, de Geus EJC, Boomsma DI, Lehtimäki T, Mangino M, Laakso M, Bouchard C, Martin NG, Kuh D, Liu Y, Linneberg A, März W, Strauch K, Kivimäki M, Harris TB, Gudnason V, Völzke H, Qi L, Järvelin MR, Chambers JC, Kooner JS, Froguel P, Kooperberg C, Vollenweider P, Hallmans G, Hansen T, Pedersen O, Metspalu A, Wareham NJ, Langenberg C, Weir DR, Porteous DJ, Boerwinkle E, Chasman DI, CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium, Abecasis GR, Barroso I, McCarthy MI, Frayling TM, O'Connell JR, van Duijn CM, Boehnke M, Heid IM, Mohlke KL, Strachan DP, Fox CS, Liu CT, Hirschhorn JN, Klein RJ, Johnson AD, Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpeläinen TO. PMID: 28448500; PMCID: PMC5407576.
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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun. 2017 04 26; 8:14977.
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, Xue L, Mahajan A, Renström F, Wu J, Qi Q, Ahmad S, Alfred T, Amin N, Bielak LF, Bonnefond A, Bragg J, Cadby G, Chittani M, Coggeshall S, Corre T, Direk N, Eriksson J, Fischer K, Gorski M, Neergaard Harder M, Horikoshi M, Huang T, Huffman JE, Jackson AU, Justesen JM, Kanoni S, Kinnunen L, Kleber ME, Komulainen P, Kumari M, Lim U, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Marten J, Middelberg RPS, Müller-Nurasyid M, Navarro P, Pérusse L, Pervjakova N, Sarti C, Smith AV, Smith JA, Stancáková A, Strawbridge RJ, Stringham HM, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van der Most PJ, Van Vliet-Ostaptchouk JV, Vedantam SL, Verweij N, Vink JM, Vitart V, Wu Y, Yengo L, Zhang W, Hua Zhao J, Zimmermann ME, Zubair N, Abecasis GR, Adair LS, Afaq S, Afzal U, Bakker SJL, Bartz TM, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Braga D, Buckley BM, Buyske S, Campbell H, Chambers JC, Collins FS, Curran JE, de Borst GJ, de Craen AJM, de Geus EJC, Dedoussis G, Delgado GE, den Ruijter HM, Eiriksdottir G, Eriksson AL, Esko T, Faul JD, Ford I, Forrester T, Gertow K, Gigante B, Glorioso N, Gong J, Grallert H, Grammer TB, Grarup N, Haitjema S, Hallmans G, Hamsten A, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie ND, Heath AC, Hernandez D, Hindorff L, Hocking LJ, Hollensted M, Holmen OL, Homuth G, Jan Hottenga J, Huang J, Hung J, Hutri-Kähönen N, Ingelsson E, James AL, Jansson JO, Jarvelin MR, Jhun MA, Jørgensen ME, Juonala M, Kähönen M, Karlsson M, Koistinen HA, Kolcic I, Kolovou G, Kooperberg C, Krämer BK, Kuusisto J, Kvaløy K, Lakka TA, Langenberg C, Launer LJ, Leander K, Lee NR, Lind L, Lindgren CM, Linneberg A, Lobbens S, Loh M, Lorentzon M, Luben R, Lubke G, Ludolph-Donislawski A, Lupoli S, Madden PAF, Männikkö R, Marques-Vidal P, Martin NG, McKenzie CA, McKnight B, Mellström D, Menni C, Montgomery GW, Musk AB, Narisu N, Nauck M, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Peyser PA, Pisinger C, Porteous DJ, Raitakari OT, Rankinen T, Rao DC, Rasmussen-Torvik LJ, Rawal R, Rice T, Ridker PM, Rose LM, Bien SA, Rudan I, Sanna S, Sarzynski MA, Sattar N, Savonen K, Schlessinger D, Scholtens S, Schurmann C, Scott RA, Sennblad B, Siemelink MA, Silbernagel G, Slagboom PE, Snieder H, Staessen JA, Stott DJ, Swertz MA, Swift AJ, Taylor KD, Tayo BO, Thorand B, Thuillier D, Tuomilehto J, Uitterlinden AG, Vandenput L, Vohl MC, Völzke H, Vonk JM, Waeber G, Waldenberger M, Westendorp RGJ, Wild S, Willemsen G, Wolffenbuttel BHR, Wong A, Wright AF, Zhao W, Zillikens MC, Baldassarre D, Balkau B, Bandinelli S, Böger CA, Boomsma DI, Bouchard C, Bruinenberg M, Chasman DI, Chen YD, Chines PS, Cooper RS, Cucca F, Cusi D, Faire U, Ferrucci L, Franks PW, Froguel P, Gordon-Larsen P, Grabe HJ, Gudnason V, Haiman CA, Hayward C, Hveem K, Johnson AD, Wouter Jukema J, Kardia SLR, Kivimaki M, Kooner JS, Kuh D, Laakso M, Lehtimäki T, Marchand LL, März W, McCarthy MI, Metspalu A, Morris AP, Ohlsson C, Palmer LJ, Pasterkamp G, Pedersen O, Peters A, Peters U, Polasek O, Psaty BM, Qi L, Rauramaa R, Smith BH, Sørensen TIA, Strauch K, Tiemeier H, Tremoli E, van der Harst P, Vestergaard H, Vollenweider P, Wareham NJ, Weir DR, Whitfield JB, Wilson JF, Tyrrell J, Frayling TM, Barroso I, Boehnke M, Deloukas P, Fox CS, Hirschhorn JN, Hunter DJ, Spector TD, Strachan DP, van Duijn CM, Heid IM, Mohlke KL, Marchini J, Loos RJF, Kilpeläinen TO, Liu CT, Borecki IB, North KE, Cupples LA. PMID: 28443625; PMCID: PMC5414044.
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017 07; 66(7):2019-2032.
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK, Teslovich TM, Blackwell TW, Bork-Jensen J, Burtt NP, Chen Y, Green T, Hartl C, Kang HM, Kumar A, Ladenvall C, Ma C, Moutsianas L, Pearson RD, Perry JRB, Rayner NW, Robertson NR, Scott LJ, van de Bunt M, Eriksson JG, Jula A, Koskinen S, Lehtimäki T, Palotie A, Raitakari OT, Jacobs SBR, Wessel J, Chu AY, Scott RA, Goodarzi MO, Blancher C, Buck G, Buck D, Chines PS, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Banks E, Carey J, Carneiro MO, DePristo M, Farjoun Y, Fennell T, Goldstein JI, Grant G, Hrabé de Angelis M, Maguire J, Neale BM, Poplin R, Purcell S, Schwarzmayr T, Shakir K, Smith JD, Strom TM, Wieland T, Lindstrom J, Brandslund I, Christensen C, Surdulescu GL, Lakka TA, Doney ASF, Nilsson P, Wareham NJ, Langenberg C, Varga TV, Franks PW, Rolandsson O, Rosengren AH, Farook VS, Thameem F, Puppala S, Kumar S, Lehman DM, Jenkinson CP, Curran JE, Hale DE, Fowler SP, Arya R, DeFronzo RA, Abboud HE, Syvänen AC, Hicks PJ, Palmer ND, Ng MCY, Bowden DW, Freedman BI, Esko T, Mägi R, Milani L, Mihailov E, Metspalu A, Narisu N, Kinnunen L, Bonnycastle LL, Swift A, Pasko D, Wood AR, Fadista J, Pollin TI, Barzilai N, Atzmon G, Glaser B, Thorand B, Strauch K, Peters A, Roden M, Müller-Nurasyid M, Liang L, Kriebel J, Illig T, Grallert H, Gieger C, Meisinger C, Lannfelt L, Musani SK, Griswold M, Taylor HA, Wilson G, Correa A, Oksa H, Scott WR, Afzal U, Tan ST, Loh M, Chambers JC, Sehmi J, Kooner JS, Lehne B, Cho YS, Lee JY, Han BG, Käräjämäki A, Qi Q, Qi L, Huang J, Hu FB, Melander O, Orho-Melander M, Below JE, Aguilar D, Wong TY, Liu J, Khor CC, Chia KS, Lim WY, Cheng CY, Chan E, Tai ES, Aung T, Linneberg A, Isomaa B, Meitinger T, Tuomi T, Hakaste L, Kravic J, Jørgensen ME, Lauritzen T, Deloukas P, Stirrups KE, Owen KR, Farmer AJ, Frayling TM, O'Rahilly SP, Walker M, Levy JC, Hodgkiss D, Hattersley AT, Kuulasmaa T, Stancáková A, Barroso I, Bharadwaj D, Chan J, Chandak GR, Daly MJ, Donnelly PJ, Ebrahim SB, Elliott P, Fingerlin T, Froguel P, Hu C, Jia W, Ma RCW, McVean G, Park T, Prabhakaran D, Sandhu M, Scott J, Sladek R, Tandon N, Teo YY, Zeggini E, Watanabe RM, Koistinen HA, Kesaniemi YA, Uusitupa M, Spector TD, Salomaa V, Rauramaa R, Palmer CNA, Prokopenko I, Morris AD, Bergman RN, Collins FS, Lind L, Ingelsson E, Tuomilehto J, Karpe F, Groop L, Jørgensen T, Hansen T, Pedersen O, Kuusisto J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Seielstad M, Wilson JG, Dupuis J, Ripatti S, Hanis CL, Florez JC, Mohlke KL, Meigs JB, Laakso M, Morris AP, Boehnke M, Altshuler D, McCarthy MI, Gloyn AL, Lindgren CM. PMID: 28341696; PMCID: PMC5482074.
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Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome. Metabolism. 2017 06; 71:125-131.
Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A. PMID: 28521865; PMCID: PMC5468004.
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4 Fields:
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Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure. Diabetes. 2017 04; 66(4):823-834.
Morton GJ, Muta K, Kaiyala KJ, Rojas JM, Scarlett JM, Matsen ME, Nelson JT, Acharya NK, Piccinini F, Stefanovski D, Bergman RN, Taborsky GJ, Kahn SE, Schwartz MW. PMID: 28115396; PMCID: PMC5360298.
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25 Fields:
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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun. 2016 11 23; 7:13357.
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, Lahti J, Luan J, Mägi R, Mahajan A, Mangino M, Medina-Gomez C, Monda KL, Nolte IM, Pérusse L, Prokopenko I, Qi L, Rose LM, Salvi E, Smith MT, Snieder H, Stancáková A, Ju Sung Y, Tachmazidou I, Teumer A, Thorleifsson G, van der Harst P, Walker RW, Wang SR, Wild SH, Willems SM, Wong A, Zhang W, Albrecht E, Couto Alves A, Bakker SJ, Barlassina C, Bartz TM, Beilby J, Bellis C, Bergman RN, Bergmann S, Blangero J, Blüher M, Boerwinkle E, Bonnycastle LL, Bornstein SR, Bruinenberg M, Campbell H, Chen YI, Chiang CW, Chines PS, Collins FS, Cucca F, Cupples LA, D'Avila F, de Geus EJ, Dedoussis G, Dimitriou M, Döring A, Eriksson JG, Farmaki AE, Farrall M, Ferreira T, Fischer K, Forouhi NG, Friedrich N, Gjesing AP, Glorioso N, Graff M, Grallert H, Grarup N, Gräßler J, Grewal J, Hamsten A, Harder MN, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Havulinna AS, Heliövaara M, Hillege H, Hofman A, Holmen O, Homuth G, Hottenga JJ, Hui J, Husemoen LL, Hysi PG, Isaacs A, Ittermann T, Jalilzadeh S, James AL, Jørgensen T, Jousilahti P, Jula A, Marie Justesen J, Justice AE, Kähönen M, Karaleftheri M, Tee Khaw K, Keinanen-Kiukaanniemi SM, Kinnunen L, Knekt PB, Koistinen HA, Kolcic I, Kooner IK, Koskinen S, Kovacs P, Kyriakou T, Laitinen T, Langenberg C, Lewin AM, Lichtner P, Lindgren CM, Lindström J, Linneberg A, Lorbeer R, Lorentzon M, Luben R, Lyssenko V, Männistö S, Manunta P, Leach IM, McArdle WL, Mcknight B, Mohlke KL, Mihailov E, Milani L, Mills R, Montasser ME, Morris AP, Müller G, Musk AW, Narisu N, Ong KK, Oostra BA, Osmond C, Palotie A, Pankow JS, Paternoster L, Penninx BW, Pichler I, Pilia MG, Polašek O, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rayner NW, Ribel-Madsen R, Rice TK, Richards M, Ridker PM, Rivadeneira F, Ryan KA, Sanna S, Sarzynski MA, Scholtens S, Scott RA, Sebert S, Southam L, Sparsø TH, Steinthorsdottir V, Stirrups K, Stolk RP, Strauch K, Stringham HM, Swertz MA, Swift AJ, Tönjes A, Tsafantakis E, van der Most PJ, Van Vliet-Ostaptchouk JV, Vandenput L, Vartiainen E, Venturini C, Verweij N, Viikari JS, Vitart V, Vohl MC, Vonk JM, Waeber G, Widén E, Willemsen G, Wilsgaard T, Winkler TW, Wright AF, Yerges-Armstrong LM, Hua Zhao J, Zillikens MC, Boomsma DI, Bouchard C, Chambers JC, Chasman DI, Cusi D, Gansevoort RT, Gieger C, Hansen T, Hicks AA, Hu F, Hveem K, Jarvelin MR, Kajantie E, Kooner JS, Kuh D, Kuusisto J, Laakso M, Lakka TA, Lehtimäki T, Metspalu A, Njølstad I, Ohlsson C, Oldehinkel AJ, Palmer LJ, Pedersen O, Perola M, Peters A, Psaty BM, Puolijoki H, Rauramaa R, Rudan I, Salomaa V, Schwarz PE, Shudiner AR, Smit JH, Sørensen TI, Spector TD, Stefansson K, Stumvoll M, Tremblay A, Tuomilehto J, Uitterlinden AG, Uusitupa M, Völker U, Vollenweider P, Wareham NJ, Watkins H, Wilson JF, Zeggini E, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, van Duijn CM, Fox C, Groop LC, Heid IM, Hunter DJ, Kaplan RC, McCarthy MI, North KE, O'Connell JR, Schlessinger D, Thorsteinsdottir U, Strachan DP, Frayling T, Hirschhorn JN, Müller-Nurasyid M, Loos RJ. PMID: 27876822; PMCID: PMC5114527.
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Insulin access to skeletal muscle is impaired during the early stages of diet-induced obesity. Obesity (Silver Spring). 2016 09; 24(9):1922-8.
Broussard JL, Castro AV, Iyer M, Paszkiewicz RL, Bediako IA, Szczepaniak LS, Szczepaniak EW, Bergman RN, Kolka CM. PMID: 27569119; PMCID: PMC5004780.
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12 Fields:
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Animals
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Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet. Diabetes. 2016 Nov; 65(11):3453-3463.
Iyer MS, Bergman RN, Korman JE, Woolcott OO, Kabir M, Victor RG, Clegg DJ, Kolka C. PMID: 27495220; PMCID: PMC5079632.
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9 Fields:
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AnimalsCells
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Transwomen and the Metabolic Syndrome: Is Orchiectomy Protective? Transgend Health. 2016; 1(1):165-171.
Nelson MD, Szczepaniak LS, Wei J, Szczepaniak E, Sánchez FJ, Vilain E, Stern JH, Bergman RN, Bairey Merz CN, Clegg DJ. PMID: 29159307; PMCID: PMC5685281.
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7
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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes. 2016 10; 65(10):3200-11.
Walford GA, Gustafsson S, Rybin D, Stancáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, Silbernagel G, Jackson AU, Appel EV, Grarup N, Lewis JP, Montasser ME, Landenvall C, Staiger H, Luan J, Frayling TM, Weedon MN, Xie W, Morcillo S, Martínez-Larrad MT, Biggs ML, Chen YD, Corbaton-Anchuelo A, Færch K, Gómez-Zumaquero JM, Goodarzi MO, Kizer JR, Koistinen HA, Leong A, Lind L, Lindgren C, Machicao F, Manning AK, Martín-Núñez GM, Rojo-Martínez G, Rotter JI, Siscovick DS, Zmuda JM, Zhang Z, Serrano-Rios M, Smith U, Soriguer F, Hansen T, Jørgensen TJ, Linnenberg A, Pedersen O, Walker M, Langenberg C, Scott RA, Wareham NJ, Fritsche A, Häring HU, Stefan N, Groop L, O'Connell JR, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, März W, Kovacs P, Stumvoll M, Psaty BM, Kuusisto J, Laakso M, Meigs JB, Dupuis J, Ingelsson E, Florez JC. PMID: 27416945; PMCID: PMC5033262.
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Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series. Diabetes Care. 2016 Sep; 39(9):1602-13.
Shankar SS, Vella A, Raymond RH, Staten MA, Calle RA, Bergman RN, Cao C, Chen D, Cobelli C, Dalla Man C, Deeg M, Dong JQ, Lee DS, Polidori D, Robertson RP, Ruetten H, Stefanovski D, Vassileva MT, Weir GC, Fryburg DA, Foundation for the National Institutes of Health ß-Cell Project Team. PMID: 27407117; PMCID: PMC5001146.
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29 Fields:
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HumansCells
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Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes. PLoS One. 2016; 11(7):e0158703.
Ionut V, Woolcott OO, Mkrtchyan HJ, Stefanovski D, Kabir M, Iyer MS, Liu H, Castro AV, Wu Q, Broussard JL, Kolka CM, Asare-Bediako I, Bergman RN. PMID: 27398720; PMCID: PMC4939956.
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3 Fields:
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AnimalsCells
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The genetic architecture of type 2 diabetes. Nature. 2016 08 04; 536(7614):41-47.
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stancáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, van der Schouw YT, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Burtt NP, Mohlke KL, Meitinger T, Groop L, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI. PMID: 27398621; PMCID: PMC5034897.
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524 Fields:
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Humans
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Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2016 06; 12(6):e1006166.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stancáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YI, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, et al. PMID: 27355579; PMCID: PMC4927064.
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Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents. Nat Med. 2016 07; 22(7):800-6.
Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW. PMID: 27213816; PMCID: PMC4938755.
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73 Fields:
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AnimalsCells
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Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. 2016 07; 65(7):2072-80.
Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, Watanabe RM, Bowden DW. PMID: 27207554; PMCID: PMC4915581.
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3 Fields:
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Humans
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Hepatic and Extrahepatic Insulin Clearance Are Differentially Regulated: Results From a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data. Diabetes. 2016 06; 65(6):1556-64.
Polidori DC, Bergman RN, Chung ST, Sumner AE. PMID: 26993071; PMCID: PMC4878413.
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53 Fields:
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Humans
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Mechanisms of improved glucose handling after metabolic surgery: the big 6. Surg Obes Relat Dis. 2016 Jul; 12(6):1192-8.
Paszkiewicz RL, Bergman RN. PMID: 27568470; PMCID: PMC5003326.
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2 Fields:
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Humans
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Inverse association between altitude and obesity: A prevalence study among andean and low-altitude adult individuals of Peru. Obesity (Silver Spring). 2016 Apr; 24(4):929-37.
Woolcott OO, Gutierrez C, Castillo OA, Elashoff RM, Stefanovski D, Bergman RN. PMID: 26935008; PMCID: PMC4814295.
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34 Fields:
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Humans
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Erratum to: Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial. Nutr Metab (Lond). 2016; 13:6.
Gower BA, Bergman R, Stefanovski D, Darnell B, Ovalle F, Fisher G, Sweatt SK, Resuehr HS, Pelkman C. PMID: 26839576; PMCID: PMC4736669.
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Metabolic effects of eradicating breath methane using antibiotics in prediabetic subjects with obesity. Obesity (Silver Spring). 2016 Mar; 24(3):576-82.
Mathur R, Chua KS, Mamelak M, Morales W, Barlow GM, Thomas R, Stefanovski D, Weitsman S, Marsh Z, Bergman RN, Pimentel M. PMID: 26833719; PMCID: PMC4769647.
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9 Fields:
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Humans
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Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial. Nutr Metab (Lond). 2016; 13:2.
Gower BA, Bergman R, Stefanovski D, Darnell B, Ovalle F, Fisher G, Sweatt SK, Resuehr HS, Pelkman C. PMID: 26766961; PMCID: PMC4711008.
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20
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet. 2015 Dec; 47(12):1415-25.
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Männistö S, McLeod O, Meyer J, Mihailov E, Mirza G, Mühleisen TW, Müller-Nurasyid M, Navarro C, Nöthen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JR, Platou CG, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurðsson G, Stancáková A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJ, Dupuis J, Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL, Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyövälti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jöcke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njølstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CN, Kathiresan S, Melander O, Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O'Callaghan CA, Gloyn AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. PMID: 26551672; PMCID: PMC4666734.
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219 Fields:
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HumansCells
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stancáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YD, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, et al. PMID: 26426971; PMCID: PMC4591371.
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Rapid development of cardiac dysfunction in a canine model of insulin resistance and moderate obesity. Diabetologia. 2016 Jan; 59(1):197-207.
Broussard JL, Nelson MD, Kolka CM, Bediako IA, Paszkiewicz RL, Smith L, Szczepaniak EW, Stefanovski D, Szczepaniak LS, Bergman RN. PMID: 26376797; PMCID: PMC5310691.
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13 Fields:
Translation:
Animals
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CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors. Am J Physiol Endocrinol Metab. 2015 Oct 15; 309(8):E747-58.
Kabir M, Iyer MS, Richey JM, Woolcott OO, Asare Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Hsu IR, Catalano KJ, Chiu JD, Ionut V, Bergman RN. PMID: 26306598; PMCID: PMC4609878.
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17 Fields:
Translation:
AnimalsCells
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Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs. Diabetologia. 2015 Nov; 58(11):2663-70.
Broussard JL, Kolka CM, Castro AV, Asare Bediako I, Paszkiewicz RL, Szczepaniak EW, Szczepaniak LS, Knutson KL, Kim SP, Bergman RN. PMID: 26254577; PMCID: PMC4591216.
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13 Fields:
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Animals
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Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets. PLoS One. 2015; 10(6):e0131033.
Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, Bradshaw H, Wu Q, Kolka CM, Bergman RN. PMID: 26075612; PMCID: PMC4468268.
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Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response. Mol Metab. 2015 Aug; 4(8):561-8.
Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW. PMID: 26266088; PMCID: PMC4529498.
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High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. PLoS One. 2015; 10(4):e0123558.
Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, Bradshaw H, Wu Q, Kolka CM, Bergman RN. PMID: 25855974; PMCID: PMC4391925.
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5 Fields:
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HumansAnimals
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Lipid-induced insulin resistance does not impair insulin access to skeletal muscle. Am J Physiol Endocrinol Metab. 2015 Jun 01; 308(11):E1001-9.
Kolka CM, Richey JM, Castro AV, Broussard JL, Ionut V, Bergman RN. PMID: 25852002; PMCID: PMC4451289.
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7 Fields:
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Animals
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New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12; 518(7538):187-196.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stancáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Smith AV, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Zhao JH, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT, ADIPOGen Consortium, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GEFOS Consortium, GENIE Consortium, GLGC, ICBP, International Endogene Consortium, LifeLines Cohort Study, MAGIC Investigators, MuTHER Consortium, PAGE Consortium, ReproGen Consortium, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, et al. PMID: 25673412; PMCID: PMC4338562.
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794 Fields:
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HumansCells
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Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12; 518(7538):197-206.
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI, Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, LifeLines Cohort Study, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, Vinkhuyzen AAE, Westra HJ, Zheng W, Zondervan KT, ADIPOGen Consortium, AGEN-BMI Working Group, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GLGC, ICBP, MAGIC Investigators, MuTHER Consortium, MIGen Consortium, PAGE Consortium, ReproGen Consortium, GENIE Consortium, International Endogene Consortium, Heath AC, Arveiler D, Bakker SJL, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, et al. PMID: 25673413; PMCID: PMC4382211.
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2155 Fields:
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HumansCells
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Glucose homeostasis during short-term and prolonged exposure to high altitudes. Endocr Rev. 2015 Apr; 36(2):149-73.
Woolcott OO, Ader M, Bergman RN. PMID: 25675133; PMCID: PMC4399271.
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54 Fields:
Translation:
Humans
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015 Jan; 11(1):e1004876.
Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, Rayner NW, Robertson NR, Beer NL, Rundle JK, Bork-Jensen J, Ladenvall C, Blancher C, Buck D, Buck G, Burtt NP, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Syvänen AC, Trakalo J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Hanis CL, Seielstad M, Wilson JG, Christensen C, Brandslund I, Rauramaa R, Surdulescu GL, Doney AS, Lannfelt L, Linneberg A, Isomaa B, Tuomi T, Jørgensen ME, Jørgensen T, Kuusisto J, Uusitupa M, Salomaa V, Spector TD, Morris AD, Palmer CN, Collins FS, Mohlke KL, Bergman RN, Ingelsson E, Lind L, Tuomilehto J, Hansen T, Watanabe RM, Prokopenko I, Dupuis J, Karpe F, Groop L, Laakso M, Pedersen O, Florez JC, Morris AP, Altshuler D, Meigs JB, Boehnke M, McCarthy MI, Lindgren CM, Gloyn AL, T2D-GENES consortium and GoT2D consortium. PMID: 25625282; PMCID: PMC4307976.
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60 Fields:
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HumansPHPublic Health
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Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 2015 May; 64(5):1853-66.
Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T, Ziegler JT, Williams AH, Stefanovski D, Cui J, Mackay AW, Henkin LF, Bergman RN, Gao X, Gauderman J, Varma R, Hanis CL, Cox NJ, Highland HM, Below JE, Williams AL, Burtt NP, Aguilar-Salinas CA, Huerta-Chagoya A, Gonzalez-Villalpando C, Orozco L, Haiman CA, Tsai MY, Johnson WC, Yao J, Rasmussen-Torvik L, Pankow J, Snively B, Jackson RD, Liu S, Nadler JL, Kandeel F, Chen YD, Bowden DW, Rich SS, Raffel LJ, Rotter JI, Watanabe RM, Wagenknecht LE. PMID: 25524916; PMCID: PMC4407862.
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51 Fields:
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Humans
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Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study. J Clin Endocrinol Metab. 2015 Mar; 100(3):E463-8.
Palmer ND, Stevens RD, Antinozzi PA, Anderson A, Bergman RN, Wagenknecht LE, Newgard CB, Bowden DW. PMID: 25423564; PMCID: PMC4333040.
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105 Fields:
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Humans
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Modest hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle. Metabolism. 2015 Feb; 64(2):330-7.
Kolka CM, Castro AV, Kirkman EL, Bergman RN. PMID: 25468139; PMCID: PMC4277905.
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1 Fields:
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AnimalsCells
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Increase in visceral fat per se does not induce insulin resistance in the canine model. Obesity (Silver Spring). 2015 Jan; 23(1):105-11.
Castro AV, Woolcott OO, Iyer MS, Kabir M, Ionut V, Stefanovski D, Kolka CM, Szczepaniak LS, Szczepaniak EW, Asare-Bediako I, Paszkiewicz RL, Broussard JL, Kim SP, Kirkman EL, Rios HC, Mkrtchyan H, Wu Q, Ader M, Bergman RN. PMID: 25322680; PMCID: PMC4276477.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014 Nov; 46(11):1173-86.
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspersen IH, Chines PS, Clarke R, Claudi-Boehm S, Cooper M, Daw EW, De Jong PA, Deelen J, Delgado G, Denny JC, Dhonukshe-Rutten R, Dimitriou M, Doney AS, Dörr M, Eklund N, Eury E, Folkersen L, Garcia ME, Geller F, Giedraitis V, Go AS, Grallert H, Grammer TB, Gräßler J, Grönberg H, de Groot LC, Groves CJ, Haessler J, Hall P, Haller T, Hallmans G, Hannemann A, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hemani G, Henders AK, Hillege HL, Hlatky MA, Hoffmann W, Hoffmann P, Holmen O, Houwing-Duistermaat JJ, Illig T, Isaacs A, James AL, Jeff J, Johansen B, Johansson Å, Jolley J, Juliusdottir T, Junttila J, Kho AN, Kinnunen L, Klopp N, Kocher T, Kratzer W, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Lu Y, Lyssenko V, Magnusson PK, Mahajan A, Maillard M, McArdle WL, McKenzie CA, McLachlan S, McLaren PJ, Menni C, Merger S, Milani L, Moayyeri A, Monda KL, Morken MA, Müller G, Müller-Nurasyid M, Musk AW, Narisu N, Nauck M, Nolte IM, Nöthen MM, Oozageer L, Pilz S, Rayner NW, Renstrom F, Robertson NR, Rose LM, Roussel R, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Schunkert H, Scott RA, Sehmi J, Seufferlein T, Shi J, Silventoinen K, Smit JH, Smith AV, Smolonska J, Stanton AV, Stirrups K, Stott DJ, Stringham HM, Sundström J, Swertz MA, Syvänen AC, Tayo BO, Thorleifsson G, Tyrer JP, van Dijk S, van Schoor NM, van der Velde N, van Heemst D, van Oort FV, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Waldenberger M, Wennauer R, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boomsma DI, Bornstein SR, Bovet P, Brambilla P, Brown MJ, Campbell H, Caulfield MJ, Chakravarti A, Collins R, Collins FS, Crawford DC, Cupples LA, Danesh J, de Faire U, den Ruijter HM, Erbel R, Erdmann J, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Gansevoort RT, Gejman PV, Gieger C, Golay A, Gottesman O, Gudnason V, Gyllensten U, Haas DW, Hall AS, Harris TB, Hattersley AT, Heath AC, Hengstenberg C, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Hovingh GK, Humphries SE, Hunt SC, Hypponen E, Jacobs KB, Jarvelin MR, Jousilahti P, Jula AM, Kaprio J, Kastelein JJ, Kayser M, Kee F, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kooner JS, Kooperberg C, Koskinen S, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lupoli S, Madden PA, Männistö S, Manunta P, Marette A, Matise TC, McKnight B, Meitinger T, Moll FL, Montgomery GW, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Ouwehand WH, Pasterkamp G, Peters A, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ritchie M, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Sebert S, Sever P, Shuldiner AR, Sinisalo J, Steinthorsdottir V, Stolk RP, Tardif JC, Tönjes A, et al. PMID: 25282103; PMCID: PMC4250049.
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931 Fields:
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Humans
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Diets high in protein or saturated fat do not affect insulin sensitivity or plasma concentrations of lipids and lipoproteins in overweight and obese adults. J Nutr. 2014 Nov; 144(11):1753-9.
Chiu S, Williams PT, Dawson T, Bergman RN, Stefanovski D, Watkins SM, Krauss RM. PMID: 25332473; PMCID: PMC4195419.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Hepatic portal vein denervation impairs oral glucose tolerance but not exenatide's effect on glycemia. Am J Physiol Endocrinol Metab. 2014 Oct 15; 307(8):E644-52.
Ionut V, Castro AV, Woolcott OO, Stefanovski D, Iyer MS, Broussard JL, Burch M, Elazary R, Kolka CM, Mkrtchyan H, Bediako IA, Bergman RN. PMID: 25117408; PMCID: PMC4200304.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Obesity, insulin resistance and comorbidities? Mechanisms of association. Arq Bras Endocrinol Metabol. 2014 Aug; 58(6):600-9.
Castro AV, Kolka CM, Kim SP, Bergman RN. PMID: 25211442; PMCID: PMC4423826.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Systems analysis and the prediction and prevention of Type 2 diabetes mellitus. Curr Opin Biotechnol. 2014 Aug; 28:165-70.
Bergman RN, Stefanovski D, Kim SP. PMID: 24976265; PMCID: PMC5931209.
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PubMed Mentions:
5 Fields:
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Humans
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Inverse association between diabetes and altitude: a cross-sectional study in the adult population of the United States. Obesity (Silver Spring). 2014 Sep; 22(9):2080-90.
Woolcott OO, Castillo OA, Gutierrez C, Elashoff RM, Stefanovski D, Bergman RN. PMID: 24890677; PMCID: PMC4149588.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring). 2014 Apr; 22(4):1157-64.
Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. PMID: 24124113; PMCID: PMC3968231.
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PubMed Mentions:
20 Fields:
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Humans
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CDKN2B expression and subcutaneous adipose tissue expandability: possible influence of the 9p21 atherosclerosis locus. Biochem Biophys Res Commun. 2014 Apr 18; 446(4):1126-31.
Svensson PA, Wahlstrand B, Olsson M, Froguel P, Falchi M, Bergman RN, McTernan PG, Hedner T, Carlsson LM, Jacobson P. PMID: 24680834; PMCID: PMC4003348.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar; 46(3):234-44.
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jöckel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyövälti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Mägi R, Männisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Mühleisen TW, Müller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njølstad I, Nöthen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segrè AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurdsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stancáková A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvänen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, et al. PMID: 24509480; PMCID: PMC3969612.
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PubMed Mentions:
574 Fields:
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Humans
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Essentiality of portal vein receptors in hypoglycemic counterregulation: direct proof via denervation in male canines. Endocrinology. 2014 Apr; 155(4):1247-54.
Ionut V, Castro AV, Woolcott OO, Stefanovski D, Iyer MS, Broussard JL, Mkrtchyan H, Burch M, Elazary R, Kirkman E, Bergman RN. PMID: 24428530; PMCID: PMC3959607.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Failure of homeostatic model assessment of insulin resistance to detect marked diet-induced insulin resistance in dogs. Diabetes. 2014 Jun; 63(6):1914-9.
Ader M, Stefanovski D, Richey JM, Kim SP, Kolka CM, Ionut V, Kabir M, Bergman RN. PMID: 24353184; PMCID: PMC4876683.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog. Obesity (Silver Spring). 2014 May; 22(5):1238-45.
Ader M, Stefanovski D, Kim SP, Richey JM, Ionut V, Catalano KJ, Hucking K, Ellmerer M, Van Citters G, Hsu IR, Chiu JD, Woolcott OO, Harrison LN, Zheng D, Lottati M, Kolka CM, Mooradian V, Dittmann J, Yae S, Liu H, Castro AV, Kabir M, Bergman RN. PMID: 24123967; PMCID: PMC3969862.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 2014 Jun; 63(6):2158-71.
Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, Assimes TL, Hao K, Yang X, Lecoeur C, Barroso I, Bonnycastle LL, Böttcher Y, Bumpstead S, Chines PS, Erdos MR, Graessler J, Kovacs P, Morken MA, Narisu N, Payne F, Stancakova A, Swift AJ, Tönjes A, Bornstein SR, Cauchi S, Froguel P, Meyre D, Schwarz PE, Häring HU, Smith U, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, Quertemous T, Lind L, Hansen T, Pedersen O, Walker M, Pfeiffer AF, Spranger J, Stumvoll M, Meigs JB, Wareham NJ, Kuusisto J, Laakso M, Langenberg C, Dupuis J, Watanabe RM, Florez JC, Ingelsson E, McCarthy MI, Prokopenko I, MAGIC Investigators. PMID: 24296717; PMCID: PMC4030103.
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PubMed Mentions:
170 Fields:
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HumansCells
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FGF19 action in the brain induces insulin-independent glucose lowering. J Clin Invest. 2013 Nov; 123(11):4799-808.
Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW. PMID: 24084738; PMCID: PMC3809800.
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113 Fields:
Translation:
AnimalsCells
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Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 2013 Oct; 62(10):3589-98.
Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U, GENESIS Consortium, RISC Consortium, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM. PMID: 23835345; PMCID: PMC3781444.
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61 Fields:
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Humans
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Macrophage gene expression in adipose tissue is associated with insulin sensitivity and serum lipid levels independent of obesity. Obesity (Silver Spring). 2013 Dec; 21(12):E571-6.
Ahlin S, Sjöholm K, Jacobson P, Andersson-Assarsson JC, Walley A, Tordjman J, Poitou C, Prifti E, Jansson PA, Borén J, Sjöström L, Froguel P, Bergman RN, Carlsson LM, Olsson B, Svensson PA. PMID: 23512687; PMCID: PMC3763968.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity (Silver Spring). 2013 Jun; 21(6):1093-103.
Ionut V, Burch M, Youdim A, Bergman RN. PMID: 23512841; PMCID: PMC4423817.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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The endothelium in diabetes: its role in insulin access and diabetic complications. Rev Endocr Metab Disord. 2013 Mar; 14(1):13-9.
Kolka CM, Bergman RN. PMID: 23306780; PMCID: PMC3593803.
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26 Fields:
Translation:
HumansAnimals
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Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care. 2013 Apr; 36(4):901-7.
Lee CC, Haffner SM, Wagenknecht LE, Lorenzo C, Norris JM, Bergman RN, Stefanovski D, Anderson AM, Rotter JI, Goodarzi MO, Hanley AJ. PMID: 23223351; PMCID: PMC3609510.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Biomarker models as surrogates for the disposition index in the Insulin Resistance Atherosclerosis Study. Diabet Med. 2012 Nov; 29(11):1399-406.
Watkins SM, Rowe MW, Kolberg JA, Wagenknecht LE, Bergman RN. PMID: 22413950; PMCID: PMC4423809.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations. Diabetes Care. 2012 Nov; 35(11):2377-83.
Szczepaniak LS, Victor RG, Mathur R, Nelson MD, Szczepaniak EW, Tyer N, Chen I, Unger RH, Bergman RN, Lingvay I. PMID: 22968187; PMCID: PMC3476895.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Performance of a multi-marker diabetes risk score in the Insulin Resistance Atherosclerosis Study (IRAS), a multi-ethnic US cohort. Diabetes Metab Res Rev. 2012 Sep; 28(6):519-26.
Rowe MW, Bergman RN, Wagenknecht LE, Kolberg JA. PMID: 22492485; PMCID: PMC5931211.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012 Sep; 44(9):981-90.
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J, Lindgren CM, Müller-Nurasyid M, Pechlivanis S, Rayner NW, Scott LJ, Wiltshire S, Yengo L, Kinnunen L, Rossin EJ, Raychaudhuri S, Johnson AD, Dimas AS, Loos RJ, Vedantam S, Chen H, Florez JC, Fox C, Liu CT, Rybin D, Couper DJ, Kao WH, Li M, Cornelis MC, Kraft P, Sun Q, van Dam RM, Stringham HM, Chines PS, Fischer K, Fontanillas P, Holmen OL, Hunt SE, Jackson AU, Kong A, Lawrence R, Meyer J, Perry JR, Platou CG, Potter S, Rehnberg E, Robertson N, Sivapalaratnam S, Stancáková A, Stirrups K, Thorleifsson G, Tikkanen E, Wood AR, Almgren P, Atalay M, Benediktsson R, Bonnycastle LL, Burtt N, Carey J, Charpentier G, Crenshaw AT, Doney AS, Dorkhan M, Edkins S, Emilsson V, Eury E, Forsen T, Gertow K, Gigante B, Grant GB, Groves CJ, Guiducci C, Herder C, Hreidarsson AB, Hui J, James A, Jonsson A, Rathmann W, Klopp N, Kravic J, Krjutškov K, Langford C, Leander K, Lindholm E, Lobbens S, Männistö S, Mirza G, Mühleisen TW, Musk B, Parkin M, Rallidis L, Saramies J, Sennblad B, Shah S, Sigurðsson G, Silveira A, Steinbach G, Thorand B, Trakalo J, Veglia F, Wennauer R, Winckler W, Zabaneh D, Campbell H, van Duijn C, Uitterlinden AG, Hofman A, Sijbrands E, Abecasis GR, Owen KR, Zeggini E, Trip MD, Forouhi NG, Syvänen AC, Eriksson JG, Peltonen L, Nöthen MM, Balkau B, Palmer CN, Lyssenko V, Tuomi T, Isomaa B, Hunter DJ, Qi L, Wellcome Trust Case Control Consortium, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Asian Genetic Epidemiology Network–Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Shuldiner AR, Roden M, Barroso I, Wilsgaard T, Beilby J, Hovingh K, Price JF, Wilson JF, Rauramaa R, Lakka TA, Lind L, Dedoussis G, Njølstad I, Pedersen NL, Khaw KT, Wareham NJ, Keinanen-Kiukaanniemi SM, Saaristo TE, Korpi-Hyövälti E, Saltevo J, Laakso M, Kuusisto J, Metspalu A, Collins FS, Mohlke KL, Bergman RN, Tuomilehto J, Boehm BO, Gieger C, Hveem K, Cauchi S, Froguel P, Baldassarre D, Tremoli E, Humphries SE, Saleheen D, Danesh J, Ingelsson E, Ripatti S, Salomaa V, Erbel R, Jöckel KH, Moebus S, Peters A, Illig T, de Faire U, Hamsten A, Morris AD, Donnelly PJ, Frayling TM, Hattersley AT, Boerwinkle E, Melander O, Kathiresan S, Nilsson PM, Deloukas P, Thorsteinsdottir U, Groop LC, Stefansson K, Hu F, Pankow JS, Dupuis J, Meigs JB, Altshuler D, Boehnke M, McCarthy MI, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. PMID: 22885922; PMCID: PMC3442244.
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PubMed Mentions:
1076 Fields:
Translation:
Humans
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet. 2012 Sep; 44(9):991-1005.
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PC, Jukema JW, Johnson T, Mahajan A, Verweij N, Thorleifsson G, Hottenga JJ, Shah S, Smith AV, Sennblad B, Gieger C, Salo P, Perola M, Timpson NJ, Evans DM, Pourcain BS, Wu Y, Andrews JS, Hui J, Bielak LF, Zhao W, Horikoshi M, Navarro P, Isaacs A, O'Connell JR, Stirrups K, Vitart V, Hayward C, Esko T, Mihailov E, Fraser RM, Fall T, Voight BF, Raychaudhuri S, Chen H, Lindgren CM, Morris AP, Rayner NW, Robertson N, Rybin D, Liu CT, Beckmann JS, Willems SM, Chines PS, Jackson AU, Kang HM, Stringham HM, Song K, Tanaka T, Peden JF, Goel A, Hicks AA, An P, Müller-Nurasyid M, Franco-Cereceda A, Folkersen L, Marullo L, Jansen H, Oldehinkel AJ, Bruinenberg M, Pankow JS, North KE, Forouhi NG, Loos RJ, Edkins S, Varga TV, Hallmans G, Oksa H, Antonella M, Nagaraja R, Trompet S, Ford I, Bakker SJ, Kong A, Kumari M, Gigante B, Herder C, Munroe PB, Caulfield M, Antti J, Mangino M, Small K, Miljkovic I, Liu Y, Atalay M, Kiess W, James AL, Rivadeneira F, Uitterlinden AG, Palmer CN, Doney AS, Willemsen G, Smit JH, Campbell S, Polasek O, Bonnycastle LL, Hercberg S, Dimitriou M, Bolton JL, Fowkes GR, Kovacs P, Lindström J, Zemunik T, Bandinelli S, Wild SH, Basart HV, Rathmann W, Grallert H, DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Maerz W, Kleber ME, Boehm BO, Peters A, Pramstaller PP, Province MA, Borecki IB, Hastie ND, Rudan I, Campbell H, Watkins H, Farrall M, Stumvoll M, Ferrucci L, Waterworth DM, Bergman RN, Collins FS, Tuomilehto J, Watanabe RM, de Geus EJ, Penninx BW, Hofman A, Oostra BA, Psaty BM, Vollenweider P, Wilson JF, Wright AF, Hovingh GK, Metspalu A, Uusitupa M, Magnusson PK, Kyvik KO, Kaprio J, Price JF, Dedoussis GV, Deloukas P, Meneton P, Lind L, Boehnke M, Shuldiner AR, van Duijn CM, Morris AD, Toenjes A, Peyser PA, Beilby JP, Körner A, Kuusisto J, Laakso M, Bornstein SR, Schwarz PE, Lakka TA, Rauramaa R, Adair LS, Smith GD, Spector TD, Illig T, de Faire U, Hamsten A, Gudnason V, Kivimaki M, Hingorani A, Keinanen-Kiukaanniemi SM, Saaristo TE, Boomsma DI, Stefansson K, van der Harst P, Dupuis J, Pedersen NL, Sattar N, Harris TB, Cucca F, Ripatti S, Salomaa V, Mohlke KL, Balkau B, Froguel P, Pouta A, Jarvelin MR, Wareham NJ, Bouatia-Naji N, McCarthy MI, Franks PW, Meigs JB, Teslovich TM, Florez JC, Langenberg C, Ingelsson E, Prokopenko I, Barroso I. PMID: 22885924; PMCID: PMC3433394.
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PubMed Mentions:
495 Fields:
Translation:
HumansAnimals
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The barrier within: endothelial transport of hormones. Physiology (Bethesda). 2012 Aug; 27(4):237-47.
Kolka CM, Bergman RN. PMID: 22875454; PMCID: PMC4423824.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study. J Clin Endocrinol Metab. 2012 Sep; 97(9):3285-91.
Miller MR, Pereira RI, Langefeld CD, Lorenzo C, Rotter JI, Chen YD, Bergman RN, Wagenknecht LE, Norris JM, Fingerlin TE. PMID: 22761463; PMCID: PMC3431582.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Swan song. Obesity (Silver Spring). 2012 Jun; 20(6):1133.
Bergman RN. PMID: 22627974.
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PubMed Mentions: Fields:
Translation:
Humans
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A better index of body adiposity. Obesity (Silver Spring). 2012 Jun; 20(6):1135.
Bergman RN. PMID: 22627975.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet. 2012 May; 8(5):e1002741.
Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF, MAGIC, DIAGRAM Consortium, GIANT Consortium, Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S. PMID: 22693455; PMCID: PMC3364960.
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PubMed Mentions:
114 Fields:
Translation:
Humans
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012 May 13; 44(6):659-69.
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G, Hamsten A, Hansson O, Harris TB, Hayward C, Heath S, Hercberg S, Hicks AA, Hingorani A, Hofman A, Hui J, Hung J, Jarvelin MR, Jhun MA, Johnson PC, Jukema JW, Jula A, Kao WH, Kaprio J, Kardia SL, Keinanen-Kiukaanniemi S, Kivimaki M, Kolcic I, Kovacs P, Kumari M, Kuusisto J, Kyvik KO, Laakso M, Lakka T, Lannfelt L, Lathrop GM, Launer LJ, Leander K, Li G, Lind L, Lindstrom J, Lobbens S, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Marmot M, Meneton P, Mohlke KL, Mooser V, Morken MA, Miljkovic I, Narisu N, O'Connell J, Ong KK, Oostra BA, Palmer LJ, Palotie A, Pankow JS, Peden JF, Pedersen NL, Pehlic M, Peltonen L, Penninx B, Pericic M, Perola M, Perusse L, Peyser PA, Polasek O, Pramstaller PP, Province MA, Räikkönen K, Rauramaa R, Rehnberg E, Rice K, Rotter JI, Rudan I, Ruokonen A, Saaristo T, Sabater-Lleal M, Salomaa V, Savage DB, Saxena R, Schwarz P, Seedorf U, Sennblad B, Serrano-Rios M, Shuldiner AR, Sijbrands EJ, Siscovick DS, Smit JH, Small KS, Smith NL, Smith AV, Stancáková A, Stirrups K, Stumvoll M, Sun YV, Swift AJ, Tönjes A, Tuomilehto J, Trompet S, Uitterlinden AG, Uusitupa M, Vikström M, Vitart V, Vohl MC, Voight BF, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Wheeler E, Widen E, Wild SH, Willems SM, Willemsen G, Wilson JF, Witteman JC, Wright AF, Yaghootkar H, Zelenika D, Zemunik T, Zgaga L, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Multiple Tissue Human Expression Resource (MUTHER) Consortium, Wareham NJ, McCarthy MI, Barroso I, Watanabe RM, Florez JC, Dupuis J, Meigs JB, Langenberg C. PMID: 22581228; PMCID: PMC3613127.
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PubMed Mentions:
494 Fields:
Translation:
Humans
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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012; 8(3):e1002607.
Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, DIAGRAM+ Consortium, MAGIC Consortium, GLGC Investigators, MuTHER Consortium, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, et al. PMID: 22479202; PMCID: PMC3315470.
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273 Fields:
Translation:
Humans
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Estimating hepatic glucokinase activity using a simple model of lactate kinetics. Diabetes Care. 2012 May; 35(5):1015-20.
Stefanovski D, Youn JH, Rees M, Watanabe RM, Ader M, Ionut V, Jackson AU, Boehnke M, Collins FS, Bergman RN. PMID: 22456868; PMCID: PMC3329822.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs. Am J Physiol Endocrinol Metab. 2012 May 01; 302(10):E1261-8.
Kim SP, Woolcott OO, Hsu IR, Stefanoski D, Harrison LN, Zheng D, Lottati M, Kolka C, Catalano KJ, Chiu JD, Kabir M, Ionut V, Bergman RN, Richey JM. PMID: 22374758; PMCID: PMC3361982.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice. Obesity (Silver Spring). 2012 Jul; 20(7):1403-12.
Alonso LC, Watanabe Y, Stefanovski D, Lee EJ, Singamsetty S, Romano LC, Zou B, Garcia-Ocaña A, Bergman RN, O'Donnell CP. PMID: 22331130; PMCID: PMC3378770.
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PubMed Mentions:
33 Fields:
Translation:
Animals
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A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One. 2012; 7(1):e29202.
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, DIAGRAM Consortium, MAGIC Investigators, Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, et al. PMID: 22238593; PMCID: PMC3251563.
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88 Fields:
Translation:
Humans
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Simplified method to isolate highly pure canine pancreatic islets. Pancreas. 2012 Jan; 41(1):31-8.
Woolcott OO, Bergman RN, Richey JM, Kirkman EL, Harrison LN, Ionut V, Lottati M, Zheng D, Hsu IR, Stefanovski D, Kabir M, Kim SP, Catalano KJ, Chiu JD, Chow RH. PMID: 21792087; PMCID: PMC4423806.
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12 Fields:
Translation:
HumansAnimals
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Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep 11; 43(10):1005-11.
Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, LifeLines Cohort Study, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, König IR, EchoGen consortium, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, AortaGen Consortium, Mitchell GF, CHARGE Consortium Heart Failure Working Group, Smith NL, KidneyGen consortium, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, CKDGen consortium, Cardiogenics consortium, CardioGram, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. PMID: 21909110; PMCID: PMC3445021.
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255 Fields:
Translation:
Humans
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11; 478(7367):103-9.
International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, CARDIoGRAM consortium, CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, CHARGE-HF consortium, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, et al. PMID: 21909115; PMCID: PMC3340926.
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PubMed Mentions:
1013 Fields:
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Humans
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Mechanisms responsible for excess weight loss after bariatric surgery. J Diabetes Sci Technol. 2011 Sep 01; 5(5):1263-82.
Ionut V, Bergman RN. PMID: 22027328; PMCID: PMC3208891.
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42 Fields:
Translation:
Humans
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Large size cells in the visceral adipose depot predict insulin resistance in the canine model. Obesity (Silver Spring). 2011 Nov; 19(11):2121-9.
Kabir M, Stefanovski D, Hsu IR, Iyer M, Woolcott OO, Zheng D, Catalano KJ, Chiu JD, Kim SP, Harrison LN, Ionut V, Lottati M, Bergman RN, Richey JM. PMID: 21836643; PMCID: PMC4423825.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Adiponectin and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care. 2011 Oct; 34(10):2231-6.
Hanley AJ, Wagenknecht LE, Norris JM, Bergman R, Anderson A, Chen YI, Lorenzo C, Haffner SM. PMID: 21816973; PMCID: PMC3177725.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA. PLoS One. 2011 Mar 30; 6(3):e18134.
Stefanovski D, Richey JM, Woolcott O, Lottati M, Zheng D, Harrison LN, Ionut V, Kim SP, Hsu I, Bergman RN. PMID: 21479217; PMCID: PMC3068147.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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A better index of body adiposity. Obesity (Silver Spring). 2011 May; 19(5):1083-9.
Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, Sebring NG, Xiang AH, Watanabe RM. PMID: 21372804; PMCID: PMC3275633.
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PubMed Mentions:
358 Fields:
Translation:
Humans
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42(11):937-48.
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson A, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, den Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Grässler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jørgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, König IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaløy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimäki T, Lettre G, Liu J, Lokki ML, Lorentzon M, Luben RN, Ludwig B, MAGIC, Manunta P, Marek D, Marre M, Martin NG, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O'Rahilly S, Ong KK, Oostra B, Paré G, Parker AN, Perola M, Pichler I, Pietiläinen KH, Platou CG, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstråle M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Surakka I, Swift AJ, Tammesoo ML, Tardif JC, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tönjes A, Tuomi T, van Meurs JB, van Ommen GJ, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CI, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widen E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kähönen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Grönberg H, Gyllensten U, Hall P, Hansen T, Harris TB, Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Jarvelin MR, Kaprio J, Karpe F, Khaw KT, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, et al. PMID: 20935630; PMCID: PMC3014648.
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1519 Fields:
Translation:
Humans
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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010 Nov; 42(11):949-60.
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Lango Allen H, Weyant RJ, Wheeler E, Wood AR, MAGIC, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJ, Gjesing AP, Grallert H, Grässler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK, Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML, Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Paré G, Parker AN, Peden JF, Pichler I, Pietiläinen KH, Platou CG, Pouta A, Ridderstråle M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ, Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JB, van Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters GB, Widen E, Wild SH, Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kähönen M, Lehtimäki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll M, Tönjes A, Viikari J, Balkau B, Ben-Shlomo Y, Bergman RN, Boeing H, Smith GD, Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jørgensen T, Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A, Midthjell K, Pedersen O, Salomaa V, Schwarz PE, Tuomi T, Tuomilehto J, Valle TT, Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI, Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A, Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Jarvelin MR, Kao WH, Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM, Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo N, Spector TD, Syvanen AC, Uda M, Uitterlinden A, Völzke H, Vollenweider P, Wilson JF, Witteman JC, Wright AF, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, Frayling TM, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, North KE, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, Hirschhorn JN, Assimes TL, Wichmann HE, Thorsteinsdottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJ, Barroso I, McCarthy MI, Fox CS, Mohlke KL, Lindgren CM. PMID: 20935629; PMCID: PMC3000924.
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512 Fields:
Translation:
Humans
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Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8.
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN. PMID: 20881960; PMCID: PMC2955183.
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PubMed Mentions:
1025 Fields:
Translation:
HumansCells
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Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care. 2010 Sep; 33(9):2098-103.
Lorenzo C, Wagenknecht LE, Rewers MJ, Karter AJ, Bergman RN, Hanley AJ, Haffner SM. PMID: 20805282; PMCID: PMC2928371.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug 05; 466(7307):707-13.
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK, Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, König IR, Khaw KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Janssens AC, Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM, Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA, Borecki IB, Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S. PMID: 20686565; PMCID: PMC3039276.
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1929 Fields:
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HumansAnimals
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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010 Jul; 42(7):579-89.
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Boström K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, MAGIC investigators, GIANT Consortium. PMID: 20581827; PMCID: PMC3080658.
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983 Fields:
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Humans
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Truth or consequences? Obesity (Silver Spring). 2010 May; 18(5):859-61.
Bergman RN. PMID: 20424601.
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Pulsatile changes in free fatty acids augment hepatic glucose production and preserves peripheral glucose homeostasis. Am J Physiol Endocrinol Metab. 2010 Jul; 299(1):E131-6.
Hsu IR, Zuniga E, Bergman RN. PMID: 20424137; PMCID: PMC2904046.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Critical role of the mesenteric depot versus other intra-abdominal adipose depots in the development of insulin resistance in young rats. Diabetes. 2010 Jun; 59(6):1416-23.
Catalano KJ, Stefanovski D, Bergman RN. PMID: 20299478; PMCID: PMC2874702.
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PubMed Mentions:
36 Fields:
Translation:
Animals
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Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 2010 May; 59(5):1266-75.
Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, Bergmann A, Berne C, Boehnke M, Bonnycastle LL, Bornstein SR, Buchanan TA, Bumpstead SJ, Böttcher Y, Chines P, Collins FS, Cooper CC, Dennison EM, Erdos MR, Ferrannini E, Fox CS, Graessler J, Hao K, Isomaa B, Jameson KA, Kovacs P, Kuusisto J, Laakso M, Ladenvall C, Mohlke KL, Morken MA, Narisu N, Nathan DM, Pascoe L, Payne F, Petrie JR, Sayer AA, Schwarz PE, Scott LJ, Stringham HM, Stumvoll M, Swift AJ, Syvänen AC, Tuomi T, Tuomilehto J, Tönjes A, Valle TT, Williams GH, Lind L, Barroso I, Quertermous T, Walker M, Wareham NJ, Meigs JB, McCarthy MI, Groop L, Watanabe RM, Florez JC, MAGIC investigators. PMID: 20185807; PMCID: PMC2857908.
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PubMed Mentions:
140 Fields:
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Humans
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Insulin enhances glucose-stimulated insulin secretion in healthy humans. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4770-5.
Bouche C, Lopez X, Fleischman A, Cypess AM, O'Shea S, Stefanovski D, Bergman RN, Rogatsky E, Stein DT, Kahn CR, Kulkarni RN, Goldfine AB. PMID: 20176932; PMCID: PMC2842068.
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PubMed Mentions:
44 Fields:
Translation:
HumansCellsCTClinical Trials
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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet. 2010 Feb; 42(2):142-8.
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jørgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Lévy-Marchal C, Mayor V, McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN, Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, Scott LJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparsø T, Swift AJ, Syddall H, Thorleifsson G, Tönjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH, GIANT consortium, MAGIC investigators, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD, Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvänen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM, Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, Pedersen O, Florez JC, McCarthy MI, Boehnke M, Barroso I, Sladek R, Froguel P, Meigs JB, Groop L, Wareham NJ, Watanabe RM. PMID: 20081857; PMCID: PMC2922003.
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PubMed Mentions:
355 Fields:
Translation:
Humans
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010 Feb; 42(2):105-16.
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF, Anders Hamsten on behalf of Procardis Consortium, MAGIC investigators, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I. PMID: 20081858; PMCID: PMC3018764.
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PubMed Mentions:
1264 Fields:
Translation:
Humans
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Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia. 2010 Apr; 53(4):679-89.
Ruchat SM, Rankinen T, Weisnagel SJ, Rice T, Rao DC, Bergman RN, Bouchard C, Pérusse L. PMID: 20043145; PMCID: PMC2840709.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
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Diet-induced obesity prevents interstitial dispersion of insulin in skeletal muscle. Diabetes. 2010 Mar; 59(3):619-26.
Kolka CM, Harrison LN, Lottati M, Chiu JD, Kirkman EL, Bergman RN. PMID: 19959760; PMCID: PMC2827487.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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The two-edged sword. Endocrinol Nutr. 2009 Dec; 56 Suppl 4:5-7.
Bergman RN. PMID: 20629221; PMCID: PMC4423800.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal. Am J Physiol Endocrinol Metab. 2010 Feb; 298(2):E346-53.
Zheng D, Ionut V, Mooradian V, Stefanovski D, Bergman RN. PMID: 19934401; PMCID: PMC2822487.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
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Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia. 2010 Feb; 53(2):281-9.
Palmer ND, Langefeld CD, Ziegler JT, Hsu F, Haffner SM, Fingerlin T, Norris JM, Chen YI, Rich SS, Haritunians T, Taylor KD, Bergman RN, Rotter JI, Bowden DW. PMID: 19902172; PMCID: PMC2809812.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Novel canine models of obese prediabetes and mild type 2 diabetes. Am J Physiol Endocrinol Metab. 2010 Jan; 298(1):E38-48.
Ionut V, Liu H, Mooradian V, Castro AV, Kabir M, Stefanovski D, Zheng D, Kirkman EL, Bergman RN. PMID: 19843874; PMCID: PMC2806110.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study. Obesity (Silver Spring). 2010 Mar; 18(3):555-62.
Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE. PMID: 19798070; PMCID: PMC3992855.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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747 flyover? Obesity (Silver Spring). 2009 Aug; 17(8):1477.
Bergman RN. PMID: 19636309.
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PubMed Mentions: Fields:
Translation:
Humans
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Insulin resistance, beta cell dysfunction and visceral adiposity as predictors of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS) Family study. Diabetologia. 2009 Oct; 52(10):2079-86.
Hanley AJ, Wagenknecht LE, Norris JM, Bryer-Ash M, Chen YI, Anderson AM, Bergman R, Haffner SM. PMID: 19641896; PMCID: PMC3992852.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 2009 Jun; 5(6):e1000508.
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN, Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Procardis Consortia, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI, Giant Consortium. PMID: 19557161; PMCID: PMC2695778.
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PubMed Mentions:
262 Fields:
Translation:
Humans
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Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle. Obesity (Silver Spring). 2009 Aug; 17(8):1486-92.
Chiu JD, Kolka CM, Richey JM, Harrison LN, Zuniga E, Kirkman EL, Bergman RN. PMID: 19521354; PMCID: PMC3417110.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
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Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet. 2009 Jun; 41(6):666-76.
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL, Wellcome Trust Case Control Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB. PMID: 19430483; PMCID: PMC2891673.
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PubMed Mentions:
592 Fields:
Translation:
Humans
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A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia. 2009 Jul; 52(7):1326-33.
Rich SS, Goodarzi MO, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, Rotter JI, Chen YD, Wagenknecht LE, Bowden DW, Bergman RN. PMID: 19430760; PMCID: PMC2793118.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1311-8.
Richey JM, Woolcott OO, Stefanovski D, Harrison LN, Zheng D, Lottati M, Hsu IR, Kim SP, Kabir M, Catalano KJ, Chiu JD, Ionut V, Kolka C, Mooradian V, Bergman RN. PMID: 19366874; PMCID: PMC3833919.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Pollyanna or Debbie Downer? Obesity (Silver Spring). 2009 Mar; 17(3):409-10.
Bergman RN. PMID: 19238137.
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PubMed Mentions: Fields:
Translation:
Humans
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Greater omentectomy improves insulin sensitivity in nonobese dogs. Obesity (Silver Spring). 2009 Apr; 17(4):674-80.
Lottati M, Kolka CM, Stefanovski D, Kirkman EL, Bergman RN. PMID: 19214178; PMCID: PMC3417107.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet. 2009 Jan; 41(1):25-34.
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN, Genetic Investigation of ANthropometric Traits Consortium. PMID: 19079261; PMCID: PMC2695662.
View in:
PubMed Mentions:
886 Fields:
Translation:
Humans
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Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet. 2009 Jan; 41(1):56-65.
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. PMID: 19060906; PMCID: PMC2881676.
View in:
PubMed Mentions:
686 Fields:
Translation:
Humans
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Variants in MTNR1B influence fasting glucose levels. Nat Genet. 2009 Jan; 41(1):77-81.
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. PMID: 19060907; PMCID: PMC2682768.
View in:
PubMed Mentions:
387 Fields:
Translation:
Humans
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Exenatide sensitizes insulin-mediated whole-body glucose disposal and promotes uptake of exogenous glucose by the liver. Diabetes. 2009 Feb; 58(2):352-9.
Zheng D, Ionut V, Mooradian V, Stefanovski D, Bergman RN. PMID: 19011168; PMCID: PMC2628608.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Evaluation of quantitative models of the effect of insulin on lipolysis and glucose disposal. Am J Physiol Regul Integr Comp Physiol. 2008 Oct; 295(4):R1089-96.
Periwal V, Chow CC, Bergman RN, Ricks M, Vega GL, Sumner AE. PMID: 18685069; PMCID: PMC2576090.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes. 2008 Nov; 57(11):3136-44.
Gaulton KJ, Willer CJ, Li Y, Scott LJ, Conneely KN, Jackson AU, Duren WL, Chines PS, Narisu N, Bonnycastle LL, Luo J, Tong M, Sprau AG, Pugh EW, Doheny KF, Valle TT, Abecasis GR, Tuomilehto J, Bergman RN, Collins FS, Boehnke M, Mohlke KL. PMID: 18678618; PMCID: PMC2570412.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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OGTT-derived measures of insulin sensitivity are confounded by factors other than insulin sensitivity itself. Obesity (Silver Spring). 2008 Aug; 16(8):1938-45.
Hücking K, Watanabe RM, Stefanovski D, Bergman RN. PMID: 18670420; PMCID: PMC3417105.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest. 2008 Jul; 118(7):2620-8.
Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jørgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. PMID: 18521185; PMCID: PMC2398737.
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PubMed Mentions:
100 Fields:
Translation:
Humans
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Exenatide can reduce glucose independent of islet hormones or gastric emptying. Am J Physiol Endocrinol Metab. 2008 Aug; 295(2):E269-77.
Ionut V, Zheng D, Stefanovski D, Bergman RN. PMID: 18492781; PMCID: PMC2519754.
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PubMed Mentions:
14 Fields:
Translation:
Animals
-
Surrogates. Obesity (Silver Spring). 2008 Apr; 16(4):721-2.
Bergman RN. PMID: 18379558.
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PubMed Mentions: Fields:
Translation:
Humans
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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet. 2008 May; 40(5):638-45.
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Boström KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, Burtt NP, Chen H, Chines PS, Daly MJ, Deodhar P, Ding CJ, Doney AS, Duren WL, Elliott KS, Erdos MR, Frayling TM, Freathy RM, Gianniny L, Grallert H, Grarup N, Groves CJ, Guiducci C, Hansen T, Herder C, Hitman GA, Hughes TE, Isomaa B, Jackson AU, Jørgensen T, Kong A, Kubalanza K, Kuruvilla FG, Kuusisto J, Langenberg C, Lango H, Lauritzen T, Li Y, Lindgren CM, Lyssenko V, Marvelle AF, Meisinger C, Midthjell K, Mohlke KL, Morken MA, Morris AD, Narisu N, Nilsson P, Owen KR, Palmer CN, Payne F, Perry JR, Pettersen E, Platou C, Prokopenko I, Qi L, Qin L, Rayner NW, Rees M, Roix JJ, Sandbaek A, Shields B, Sjögren M, Steinthorsdottir V, Stringham HM, Swift AJ, Thorleifsson G, Thorsteinsdottir U, Timpson NJ, Tuomi T, Tuomilehto J, Walker M, Watanabe RM, Weedon MN, Willer CJ, Wellcome Trust Case Control Consortium, Illig T, Hveem K, Hu FB, Laakso M, Stefansson K, Pedersen O, Wareham NJ, Barroso I, Hattersley AT, Collins FS, Groop L, McCarthy MI, Boehnke M, Altshuler D. PMID: 18372903; PMCID: PMC2672416.
View in:
PubMed Mentions:
986 Fields:
Translation:
Humans
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What for genetics? Obesity (Silver Spring). 2008 Mar; 16(3):507-8.
Bergman RN. PMID: 18311116.
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PubMed Mentions: Fields:
Translation:
Humans
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Ethnic heterogeneity in glucoregulatory function during treatment with atypical antipsychotics in patients with schizophrenia. J Psychiatr Res. 2008 Oct; 42(13):1076-85.
Ader M, Garvey WT, Phillips LS, Nemeroff CB, Gharabawi G, Mahmoud R, Greenspan A, Berry SA, Musselman DL, Morein J, Zhu Y, Mao L, Bergman RN. PMID: 18295798; PMCID: PMC3769976.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes. 2008 Apr; 57(4):1093-100.
Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW. PMID: 18252897.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Watch out for the little guy. Obesity (Silver Spring). 2008 Feb; 16(2):219-20.
Bergman RN. PMID: 18239626.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Direct administration of insulin into skeletal muscle reveals that the transport of insulin across the capillary endothelium limits the time course of insulin to activate glucose disposal. Diabetes. 2008 Apr; 57(4):828-35.
Chiu JD, Richey JM, Harrison LN, Zuniga E, Kolka CM, Kirkman E, Ellmerer M, Bergman RN. PMID: 18223011.
View in:
PubMed Mentions:
42 Fields:
Translation:
Animals
-
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet. 2008 Feb; 40(2):198-203.
Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Scott LJ, Dei M, Lai S, Albai G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Ben-Shlomo Y, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, Davey Smith G, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL. PMID: 18193045; PMCID: PMC2914680.
View in:
PubMed Mentions:
204 Fields:
Translation:
HumansCells
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet. 2008 Feb; 40(2):161-9.
Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, Albai G, Swift AJ, Morken MA, Narisu N, Bennett D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen WM, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R, Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR. PMID: 18193043; PMCID: PMC5206900.
View in:
PubMed Mentions:
837 Fields:
Translation:
Humans
-
Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 2008 Apr; 57(4):1048-56.
Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. PMID: 18162503; PMCID: PMC4447520.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. J Clin Endocrinol Metab. 2008 Jan; 93(1):304-9.
Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW. PMID: 17971425; PMCID: PMC2190750.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Deconvolution as a novel approach to analyze moment-to-moment free fatty acid release. Obesity (Silver Spring). 2007 Oct; 15(10):2416-23.
Hücking K, Hsu IR, Ionut V, Bergman RN. PMID: 17925467.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Metabolic syndrome, hyperinsulinemia, and cancer. Am J Clin Nutr. 2007 09; 86(3):s867-71.
Hsu IR, Kim SP, Kabir M, Bergman RN. PMID: 18265480.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
-
Orchestration of glucose homeostasis: from a small acorn to the California oak. Diabetes. 2007 Jun; 56(6):1489-501.
Bergman RN. PMID: 17526912.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimals
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science. 2007 Jun 01; 316(5829):1341-5.
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li XY, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. PMID: 17463248; PMCID: PMC3214617.
View in:
PubMed Mentions:
1321 Fields:
Translation:
HumansCells
-
The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. BMC Endocr Disord. 2007 Mar 30; 7:1.
Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, Sharma AJ, Bergman RN, Taylor KD, Saad MF, Norris JM. PMID: 17397545; PMCID: PMC1852562.
View in:
PubMed Mentions:
16 Fields:
-
Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1581-9.
Kim SP, Ellmerer M, Kirkman EL, Bergman RN. PMID: 17284579.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am J Med. 2007 Feb; 120(2 Suppl 1):S3-8; discussion S29-32.
Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, Kabir M, Richey JM, Ader M. PMID: 17296343.
View in:
PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
-
Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1590-8.
Kim SP, Catalano KJ, Hsu IR, Chiu JD, Richey JM, Bergman RN. PMID: 17264230.
View in:
PubMed Mentions:
56 Fields:
Translation:
Animals
-
Frequency of hypoglycaemia during the intravenous glucose tolerance test in overweight children. Int J Pediatr Obes. 2007; 2(2):122-5.
Cruz ML, Weigensberg MJ, Bergman RN, Goran MI. PMID: 17763019.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
-
[Orchestration of homeostasis of glucose metabolism]. Journ Annu Diabetol Hotel Dieu. 2007; 127-38.
Bergman RN. PMID: 18610764.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes. 2007 Jan; 56(1):256-64.
Willer CJ, Bonnycastle LL, Conneely KN, Duren WL, Jackson AU, Scott LJ, Narisu N, Chines PS, Skol A, Stringham HM, Petrie J, Erdos MR, Swift AJ, Enloe ST, Sprau AG, Smith E, Tong M, Doheny KF, Pugh EW, Watanabe RM, Buchanan TA, Valle TT, Bergman RN, Tuomilehto J, Mohlke KL, Collins FS, Boehnke M. PMID: 17192490.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q. Hum Hered. 2007; 63(1):17-25.
Shtir C, Nagakawa IS, Duren WL, Conneely KN, Scott LJ, Silander K, Valle TT, Tuomilehto J, Buchanan TA, Bergman RN, Collins FS, Boehnke M, Watanabe RM. PMID: 17179727; PMCID: PMC2923439.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype. J Clin Endocrinol Metab. 2007 Jan; 92(1):293-6.
Goodarzi MO, Taylor KD, Guo X, Hokanson JE, Haffner SM, Cui J, Chen YD, Wagenknecht LE, Bergman RN, Rotter JI. PMID: 17032721.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes. 2006 Sep; 55(9):2649-53.
Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M. PMID: 16936217.
View in:
PubMed Mentions:
100 Fields:
Translation:
Humans
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Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes. 2006 Sep; 55(9):2534-40.
Bonnycastle LL, Willer CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, Chines PS, Narisu N, Scott LJ, Enloe ST, Swift AJ, Duren WL, Stringham HM, Erdos MR, Riebow NL, Buchanan TA, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Boehnke M, Collins FS. PMID: 16936201.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Dimensional analysis of MINMOD leads to definition of the disposition index of glucose regulation and improved simulation algorithm. Biomed Eng Online. 2006 Jul 14; 5:44.
Nittala A, Ghosh S, Stefanovski D, Bergman R, Wang X. PMID: 16842624; PMCID: PMC1560383.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. Diabetes. 2006 Jun; 55(6):1723-30.
Guo X, Saad MF, Langefeld CD, Williams AH, Cui J, Taylor KD, Norris JM, Jinagouda S, Darwin CH, Mitchell BD, Bergman RN, Sutton B, Chen YD, Wagenknecht LE, Bowden DW, Rotter JI. PMID: 16731835.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Association of chairs of departments of physiology 2005 survey results. Physiologist. 2006 Jun; 49(3):153, 155-6, 158-9.
Moss RL, Bergman RN. PMID: 16805365.
View in:
PubMed Mentions: Fields:
Translation:
Humans
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Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake. Diabetes. 2006 Jun; 55(6):1769-75.
Ellmerer M, Hamilton-Wessler M, Kim SP, Huecking K, Kirkman E, Chiu J, Richey J, Bergman RN. PMID: 16731841.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Exogenously imposed postprandial-like rises in systemic glucose and GLP-1 do not produce an incretin effect, suggesting an indirect mechanism of GLP-1 action. Am J Physiol Endocrinol Metab. 2006 Oct; 291(4):E779-85.
Ionut V, Liberty IF, Hucking K, Lottati M, Stefanovski D, Zheng D, Bergman RN. PMID: 16720628.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2006 Apr; 55(4):911-8.
Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW. PMID: 16567510.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol. 2006 Feb; 30(2):180-90.
Willer CJ, Scott LJ, Bonnycastle LL, Jackson AU, Chines P, Pruim R, Bark CW, Tsai YY, Pugh EW, Doheny KF, Kinnunen L, Mohlke KL, Valle TT, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. PMID: 16374835.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Why visceral fat is bad: mechanisms of the metabolic syndrome. Obesity (Silver Spring). 2006 Feb; 14 Suppl 1:16S-19S.
Bergman RN, Kim SP, Catalano KJ, Hsu IR, Chiu JD, Kabir M, Hucking K, Ader M. PMID: 16642958.
View in:
PubMed Mentions:
131 Fields:
Translation:
HumansAnimals
-
Minimal model: perspective from 2005. Horm Res. 2005; 64 Suppl 3:8-15.
Bergman RN. PMID: 16439839.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
-
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet. 2005 Nov; 118(2):245-54.
Mohlke KL, Jackson AU, Scott LJ, Peck EC, Suh YD, Chines PS, Watanabe RM, Buchanan TA, Conneely KN, Erdos MR, Narisu N, Enloe S, Valle TT, Tuomilehto J, Bergman RN, Boehnke M, Collins FS. PMID: 16142453.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
The genetic basis of glucose homeostasis. Curr Diabetes Rev. 2005 Aug; 1(3):221-6.
Rich SS, Bergman RN. PMID: 18220598.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns. Mol Genet Metab. 2005 Aug; 85(4):323-7.
Mohlke KL, Skol AD, Scott LJ, Valle TT, Bergman RN, Tuomilehto J, Boehnke M, Collins FS, FUSION Study Group. PMID: 15936967.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase. Metabolism. 2005 Jul; 54(7):902-9.
Sumner AE, Vega GL, Genovese DJ, Finley KB, Bergman RN, Boston RC. PMID: 15988699.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
-
Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes. 2005 Jul; 54(7):2251-5.
Teran-Garcia M, Santoro N, Rankinen T, Bergeron J, Rice T, Leon AS, Rao DC, Skinner JS, Bergman RN, Després JP, Bouchard C, HERITAGE Family Study. PMID: 15983229.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. Diabetologia. 2005 Jun; 48(6):1142-9.
An P, Teran-Garcia M, Rice T, Rankinen T, Weisnagel SJ, Bergman RN, Boston RC, Mandel S, Stefanovski D, Leon AS, Skinner JS, Rao DC, Bouchard C, HERITAGE Family Study. PMID: 15868134.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Abdominal obesity predicts declining insulin sensitivity in non-obese normoglycaemics: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Obes Metab. 2005 May; 7(3):230-8.
Karter AJ, D'Agostino RB, Mayer-Davis EJ, Wagenknecht LE, Hanley AJ, Hamman RF, Bergman R, Saad MF, Haffner SM, IRAS investigators. PMID: 15811139.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia. 2005 May; 48(5):967-75.
Ionut V, Hucking K, Liberty IF, Bergman RN. PMID: 15830188.
View in:
PubMed Mentions:
31 Fields:
Translation:
Animals
-
Atypical antipsychotics and glucose homeostasis. J Clin Psychiatry. 2005 Apr; 66(4):504-14.
Bergman RN, Ader M. PMID: 15816794.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
-
AKA-Glucose: a program for kinetic and epidemiological analysis of frequently sampled intravenous glucose tolerance test data using database technology. Diabetes Technol Ther. 2005 Apr; 7(2):298-307.
Boston RC, Moate PJ, Stefanovski D, Sumner AE, Bergman RN. PMID: 15857232.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes. 2005 Mar; 54(3):862-71.
Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, Kabir M, Bergman RN. PMID: 15734866.
View in:
PubMed Mentions:
46 Fields:
Translation:
Animals
-
Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. Diabetes Care. 2005 Jan; 28(1):108-14.
Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C, HERITAGE Family Study. PMID: 15616242.
View in:
PubMed Mentions:
118 Fields:
Translation:
Humans
-
Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family study and Oulu diabetic study. Ann Med. 2005; 37(2):141-50.
Ukkola O, Santaniemi M, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Kesäniemi YA, Bouchard C. PMID: 16028335.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Increased susceptibility to insulin resistance associated with abdominal obesity in aging rats. Obes Res. 2005 Jan; 13(1):11-20.
Catalano KJ, Bergman RN, Ader M. PMID: 15761159.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. Int J Obes (Lond). 2005 Jan; 29(1):67-77.
Norris JM, Langefeld CD, Scherzinger AL, Rich SS, Bookman E, Beck SR, Saad MF, Haffner SM, Bergman RN, Bowden DW, Wagenknecht LE. PMID: 15534617.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 2005 Jan; 54(1):290-5.
Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN, Insulin Resistance Atherosclerosis Study (IRAS) Family Study. PMID: 15616041.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. Am J Physiol Endocrinol Metab. 2005 Feb; 288(2):E454-61.
Kabir M, Catalano KJ, Ananthnarayan S, Kim SP, Van Citters GW, Dea MK, Bergman RN. PMID: 15522994.
View in:
PubMed Mentions:
117 Fields:
Translation:
Animals
-
Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 2004 Nov; 53(11):3013-9.
Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW, insulin resistance atherosclerosis study (IRAS) family study. PMID: 15504985.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sensitive tissues. Diabetes. 2004 Nov; 53(11):2741-7.
Ellmerer M, Kim SP, Hamilton-Wessler M, Hücking K, Kirkman E, Bergman RN. PMID: 15504953.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia. 2004 Oct; 47(10):1782-8.
Conneely KN, Silander K, Scott LJ, Mohlke KL, Lazaridis KN, Valle TT, Tuomilehto J, Bergman RN, Watanabe RM, Buchanan TA, Collins FS, Boehnke M. PMID: 15517149; PMCID: PMC1249496.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
The multiphasic profile of free fatty acids during the intravenous glucose tolerance test is unresponsive to exogenous insulin. Metabolism. 2004 Sep; 53(9):1202-7.
Sumner AE, Bergman RN, Vega GL, Genovese DJ, Cochran CS, Pacak K, Watanabe RM, Boston RC. PMID: 15334385.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Investigation of the effect of acepromazine on intravenous glucose tolerance tests in dogs. Am J Vet Res. 2004 Aug; 65(8):1124-7.
Ionut V, Kirkman EL, Bergman RN. PMID: 15334847.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2004 Jul; 53(7):1866-75.
Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN, Insulin Resistance Atherosclerosis Study Family Study. PMID: 15220212.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: the HERITAGE family study. Diabetes. 2004 Jun; 53(6):1603-8.
Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O, Boulé N, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Bouchard C. PMID: 15161768.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study. Hypertension. 2004 Jun; 43(6):1324-31.
Saad MF, Rewers M, Selby J, Howard G, Jinagouda S, Fahmi S, Zaccaro D, Bergman RN, Savage PJ, Haffner SM. PMID: 15123571.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Insulin sensitivity, body fat distribution, and family diabetes history: the IRAS Family Study. Obes Res. 2004 May; 12(5):831-9.
Mitchell BD, Zaccaro D, Wagenknecht LE, Scherzinger AL, Bergman RN, Haffner SM, Hokanson J, Norris JM, Rotter JI, Saad MF. PMID: 15166304.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes. 2004 Apr; 53(4):1141-9.
Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, Fingerlin TE, Dhanjal SK, Valle TT, Bergman RN, Tuomilehto J, Watanabe RM, Boehnke M, Collins FS. PMID: 15047633.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansCells
-
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes. 2004 Mar; 53(3):821-9.
Silander K, Scott LJ, Valle TT, Mohlke KL, Stringham HM, Wiles KR, Duren WL, Doheny KF, Pugh EW, Chines P, Narisu N, White PP, Fingerlin TE, Jackson AU, Li C, Ghosh S, Magnuson VL, Colby K, Erdos MR, Hill JE, Hollstein P, Humphreys KM, Kasad RA, Lambert J, Lazaridis KN, Lin G, Morales-Mena A, Patzkowski K, Pfahl C, Porter R, Rha D, Segal L, Suh YD, Tovar J, Unni A, Welch C, Douglas JA, Epstein MP, Hauser ER, Hagopian W, Buchanan TA, Watanabe RM, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. PMID: 14988269.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Insulin sensitivity, insulinemia, and coronary artery disease: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2004 Mar; 27(3):781-7.
Rewers M, Zaccaro D, D'Agostino R, Haffner S, Saad MF, Selby JV, Bergman R, Savage P, Insulin Resistance Atherosclerosis Study Investigators. PMID: 14988302.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab. 2004 Jan; 89(1):207-12.
Goran MI, Bergman RN, Avila Q, Watkins M, Ball GD, Shaibi GQ, Weigensberg MJ, Cruz ML. PMID: 14715851.
View in:
PubMed Mentions:
96 Fields:
Translation:
Humans
-
Estimation of metabolic flux from dominant rate constants in vivo: application to brain and heart. Metab Eng. 2004 Jan; 6(1):59-74.
Cohen DM, Bergman RN. PMID: 14734256.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
Epidemiology of classic Kaposi's sarcoma in the Israeli Jewish population between 1960 and 1998. Br J Cancer. 2003 Nov 03; 89(9):1657-60.
Guttman-Yassky E, Bar-Chana M, Yukelson A, Linn S, Friedman-Birnbaum R, Bergman R, Sarid R, Silbermann M. PMID: 14583765; PMCID: PMC2394430.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Insulin action and distribution of tissue blood flow. J Clin Endocrinol Metab. 2003 Oct; 88(10):4556-8.
Bergman RN. PMID: 14557421.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors? Diabetes Care. 2003 Oct; 26(10):2796-803.
Haffner SM, D'Agostino R, Festa A, Bergman RN, Mykkänen L, Karter A, Saad MF, Wagenknecht LE. PMID: 14514582.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog. Diabetes. 2003 Oct; 52(10):2453-60.
Kim SP, Ellmerer M, Van Citters GW, Bergman RN. PMID: 14514627.
View in:
PubMed Mentions:
53 Fields:
Translation:
Animals
-
Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 2003 Oct; 52(10):2490-6.
Wagenknecht LE, Langefeld CD, Scherzinger AL, Norris JM, Haffner SM, Saad MF, Bergman RN. PMID: 14514631.
View in:
PubMed Mentions:
105 Fields:
Translation:
Humans
-
Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulin. Diabetes. 2003 Aug; 52(8):2168-74.
Bergman RN, Zaccaro DJ, Watanabe RM, Haffner SM, Saad MF, Norris JM, Wagenknecht LE, Hokanson JE, Rotter JI, Rich SS. PMID: 12882937.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
Mechanism of action in dogs of slow-acting insulin analog O346. J Clin Endocrinol Metab. 2003 May; 88(5):2256-62.
Ellmerer M, Hamilton-Wessler M, Kim SP, Dea MK, Kirkman E, Perianayagam A, Markussen J, Bergman RN. PMID: 12727983.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol. 2003 Apr; 13(4):211-7.
Henkin L, Bergman RN, Bowden DW, Ellsworth DL, Haffner SM, Langefeld CD, Mitchell BD, Norris JM, Rewers M, Saad MF, Stamm E, Wagenknecht LE, Rich SS. PMID: 12684185.
View in:
PubMed Mentions:
93 Fields:
Translation:
Humans
-
Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study. Metabolism. 2003 Feb; 52(2):246-53.
An P, Hong Y, Weisnagel SJ, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Chagnon YC, Bergman RN, Bouchard C, Rao DC. PMID: 12601641.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Influence of family history of type 2 diabetes on insulin sensitivity in prepubertal children. J Clin Endocrinol Metab. 2003 Jan; 88(1):192-5.
Goran MI, Coronges K, Bergman RN, Cruz ML, Gower BA. PMID: 12519851.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther. 2003; 5(6):1003-15.
Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN. PMID: 14709204.
View in:
PubMed Mentions:
199 Fields:
Translation:
Humans
-
Burst-like control of lipolysis by the sympathetic nervous system in vivo. J Clin Invest. 2003 Jan; 111(2):257-64.
Hücking K, Hamilton-Wessler M, Ellmerer M, Bergman RN. PMID: 12531882; PMCID: PMC151855.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
The minimal model of glucose regulation: a biography. Adv Exp Med Biol. 2003; 537:1-19.
Bergman RN. PMID: 14995025.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding. J Clin Endocrinol Metab. 2002 Nov; 87(11):5191-8.
van Citters GW, Kabir M, Kim SP, Mittelman SD, Dea MK, Brubaker PL, Bergman RN. PMID: 12414891.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes. Eur J Clin Invest. 2002 Jun; 32 Suppl 3:35-45.
Bergman RN, Finegood DT, Kahn SE. PMID: 12028373.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
-
Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study. Diabetes. 2002 Apr; 51(4):1263-70.
Hanley AJ, D'Agostino R, Wagenknecht LE, Saad MF, Savage PJ, Bergman R, Haffner SM, Insluin Resistance Atrherosclerosis Study. PMID: 11916954.
View in:
PubMed Mentions:
37 Fields:
Translation:
Humans
-
Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion. Diabetes. 2002 Mar; 51(3):574-82.
Hamilton-Wessler M, Ader M, Dea MK, Moore D, Loftager M, Markussen J, Bergman RN. PMID: 11872653.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake. Diabetes. 2002 Mar; 51(3):762-9.
Dea MK, Hamilton-Wessler M, Ader M, Moore D, Schäffer L, Loftager M, Vølund A, Bergman RN. PMID: 11872677.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
Extreme insulin resistance of the central adipose depot in vivo. Diabetes. 2002 Mar; 51(3):755-61.
Mittelman SD, Van Citters GW, Kirkman EL, Bergman RN. PMID: 11872676.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
-
Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes. 2002 Feb; 51 Suppl 1:S212-20.
Bergman RN, Ader M, Huecking K, Van Citters G. PMID: 11815482.
View in:
PubMed Mentions:
206 Fields:
Translation:
Humans
-
Utility of a surrogate measure of insulin resistance in American Indians: the Strong Heart Study. Ethn Dis. 2002; 12(4):523-9.
Resnick HE, Bergman RN, Henderson JA, Nez-Henderson P, Howard BV. PMID: 12477138.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. Am J Physiol Endocrinol Metab. 2001 Oct; 281(4):E757-65.
Gresl TA, Colman RJ, Roecker EB, Havighurst TC, Huang Z, Allison DB, Bergman RN, Kemnitz JW. PMID: 11551852.
View in:
PubMed Mentions:
46 Fields:
Translation:
Animals
-
Hypotrichosis with juvenile macular dystrophy is caused by a mutation in CDH3, encoding P-cadherin. Nat Genet. 2001 Oct; 29(2):134-6.
Sprecher E, Bergman R, Richard G, Lurie R, Shalev S, Petronius D, Shalata A, Anbinder Y, Leibu R, Perlman I, Cohen N, Szargel R. PMID: 11544476.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E375-83.
Fosgerau K, Mittelman SD, Sunehag A, Dea MK, Lundgren K, Bergman RN. PMID: 11440915.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns. Genome Res. 2001 Jul; 11(7):1221-6.
Mohlke KL, Lange EM, Valle TT, Ghosh S, Magnuson VL, Silander K, Watanabe RM, Chines PS, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. PMID: 11435404; PMCID: PMC311096.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. Diabetes. 2001 Apr; 50(4):886-90.
Douglas JA, Erdos MR, Watanabe RM, Braun A, Johnston CL, Oeth P, Mohlke KL, Valle TT, Ehnholm C, Buchanan TA, Bergman RN, Collins FS, Boehnke M, Tuomilehto J. PMID: 11289057.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Metab Res Rev. 2001 Mar-Apr; 17(2):137-45.
Mayer-Davis EJ, Levin S, Bergman RN, D'Agostino RB, Karter AJ, Saad MF, Insulin Resistance Atherosclerosis Study (IRAS). PMID: 11307179.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes. 2001 Feb; 50(2):399-403.
Hevener AL, Bergman RN, Donovan CM. PMID: 11272153.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Central role of the adipocyte in the metabolic syndrome. J Investig Med. 2001 Jan; 49(1):119-26.
Bergman RN, Van Citters GW, Mittelman SD, Dea MK, Hamilton-Wessler M, Kim SP, Ellmerer M. PMID: 11217141.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes. 2000 Dec; 49(12):2116-25.
Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN. PMID: 11118015.
View in:
PubMed Mentions:
65 Fields:
Translation:
Animals
-
Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity. Diabetes. 2000 Dec; 49(12):2087-93.
Dea MK, Van Citters GW, Ader M, Mittelman SD, Sunehag AL, Bergman RN. PMID: 11118011.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab. 2000 Nov; 85(11):4396-402.
Caumo A, Bergman RN, Cobelli C. PMID: 11095485.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends Endocrinol Metab. 2000 Nov; 11(9):351-6.
Bergman RN, Ader M. PMID: 11042464.
View in:
PubMed Mentions:
163 Fields:
Translation:
HumansAnimals
-
Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab. 2000 Sep; 279(3):E630-7.
Mittelman SD, Bergman RN. PMID: 10950832.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. J Clin Invest. 2000 Aug; 106(3):421-30.
Getty L, Panteleon AE, Mittelman SD, Dea MK, Bergman RN. PMID: 10930445; PMCID: PMC314322.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein? Diabetologia. 2000 Jul; 43(7):946-52.
Bergman RN. PMID: 10952470.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
Carotid artery atherosclerosis in type-2 diabetic and nondiabetic subjects with and without symptomatic coronary artery disease (The Insulin Resistance Atherosclerosis Study). Am J Cardiol. 2000 Jun 15; 85(12):1395-400.
Haffner SM, Agostino RD, Saad MF, O'Leary DH, Savage PJ, Rewers M, Selby J, Bergman RN, Mykkänen L. PMID: 10856382.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Androgenetic alopecia in heterozygous carriers of a mutation in the human hairless gene. J Am Acad Dermatol. 2000 Jun; 42(6):978-82.
Sprecher E, Shalata A, Dabhah K, Futerman B, Lin S, Szargel R, Bergman R, Friedman-Birnbaum R, Cohen N. PMID: 10827399.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Validation of methods for measurement of insulin secretion in humans in vivo. Diabetes. 2000 Apr; 49(4):580-8.
Kjems LL, Christiansen E, Vølund A, Bergman RN, Madsbad S. PMID: 10871195.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
-
Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion. J Clin Endocrinol Metab. 2000 Apr; 85(4):1407-11.
Woods KA, Camacho-Hübner C, Bergman RN, Barter D, Clark AJ, Savage MO. PMID: 10770174.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics. Diabetes. 2000 Mar; 49(3):373-82.
Watanabe RM, Bergman RN. PMID: 10868958.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes. 2000 Mar; 49(3):399-408.
Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF. PMID: 10868961.
View in:
PubMed Mentions:
64 Fields:
Translation:
Humans
-
Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes. 2000 Jan; 49(1):8-12.
Hevener AL, Bergman RN, Donovan CM. PMID: 10615943.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Angiotensin II induces insulin resistance independent of changes in interstitial insulin. Am J Physiol. 1999 11; 277(5):E920-6.
Richey JM, Ader M, Moore D, Bergman RN. PMID: 10567021.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin. Diabetologia. 1999 Oct; 42(10):1254-63.
Hamilton-Wessler M, Ader M, Dea M, Moore D, Jorgensen PN, Markussen J, Bergman RN. PMID: 10525669.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Atrichia with papular lesions resulting from a nonsense mutation within the human hairless gene. J Invest Dermatol. 1999 Oct; 113(4):687-90.
Sprecher E, Lestringant GG, Szargel R, Bergman R, Labay V, Frossard PM, Friedman-Birnbaum R, Cohen N. PMID: 10504459.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol. 1999 06; 276(6):E1055-66.
Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF. PMID: 10362618.
View in:
PubMed Mentions:
62 Fields:
Translation:
Humans
-
Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Hum Hered. 1999 Jun; 49(3):159-68.
Watanabe RM, Valle T, Hauser ER, Ghosh S, Eriksson J, Kohtamäki K, Ehnholm C, Tuomilehto J, Collins FS, Bergman RN, Boehnke M. PMID: 10364681.
View in:
PubMed Mentions:
50 Fields:
Translation:
Humans
-
Failure of acute hyperinsulinemia to alter blood pressure is not due to baroreceptor feedback. Am J Hypertens. 1999 Apr; 12(4 Pt 1):405-13.
Richey JM, Poulin RA, Buchanan TA, Galperin E, Moore DM, Bergman RN. PMID: 10232501.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):2198-203.
Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J, Eldridge W, Shapiro S, Martin C, Witt A, So A, Chang J, Shurtleff B, Porter R, Kudelko K, Unni A, Segal L, Sharaf R, Blaschak-Harvan J, Eriksson J, Tenkula T, Vidgren G, Ehnholm C, Tuomilehto-Wolf E, Hagopian W, Buchanan TA, Tuomilehto J, Bergman RN, Collins FS, Boehnke M. PMID: 10051618; PMCID: PMC26760.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. Diabetologia. 1999 Feb; 42(2):238-44.
Ghosh S, Langefeld CD, Ally D, Watanabe RM, Hauser ER, Magnuson VL, Nylund SJ, Valle T, Eriksson J, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. PMID: 10064105.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Atrichia with papular lesions maps to 8p in the region containing the human hairless gene. Am J Med Genet. 1998 Dec 28; 80(5):546-50.
Sprecher E, Bergman R, Szargel R, Raz T, Labay V, Ramon M, Baruch-Gershoni R, Friedman-Birnbaum R, Cohen N. PMID: 9880231.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile. Diabetes. 1998 Dec; 47(12):1941-7.
Getty L, Hamilton-Wessler M, Ader M, Dea MK, Bergman RN. PMID: 9836528.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Evidence for direct action of alloxan to induce insulin resistance at the cellular level. Diabetologia. 1998 Nov; 41(11):1327-36.
Ader M, Richey JM, Bergman RN. PMID: 9833941.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Proinsulin and insulin concentrations in relation to carotid wall thickness: Insulin Resistance Atherosclerosis Study. Stroke. 1998 Aug; 29(8):1498-503.
Haffner SM, D'Agostino R, Mykkänen L, Hales CN, Savage PJ, Bergman RN, O'Leary D, Rewers M, Selby J, Tracy R, Saad MF. PMID: 9707183.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Ability of alternative indices of insulin sensitivity to predict cardiovascular risk: comparison with the "minimal model". Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Ann Epidemiol. 1998 Aug; 8(6):358-69.
Howard G, Bergman R, Wagenknecht LE, Haffner SM, Savage PJ, Saad MF, Laws A, D'Agostino RB. PMID: 9708871.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care. 1998 Jun; 21(6):949-58.
Valle T, Tuomilehto J, Bergman RN, Ghosh S, Hauser ER, Eriksson J, Nylund SJ, Kohtamäki K, Toivanen L, Vidgren G, Tuomilehto-Wolf E, Ehnholm C, Blaschak J, Langefeld CD, Watanabe RM, Magnuson V, Ally DS, Hagopian WA, Ross E, Buchanan TA, Collins F, Boehnke M. PMID: 9614613.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes. 1998 May; 47(5):714-20.
Steil GM, Rebrin K, Mittelman SD, Bergman RN. PMID: 9588441.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. JAMA. 1998 Mar 04; 279(9):669-74.
Mayer-Davis EJ, D'Agostino R, Karter AJ, Haffner SM, Rewers MJ, Saad M, Bergman RN. PMID: 9496984.
View in:
PubMed Mentions:
131 Fields:
Translation:
Humans
-
Diabetic dermopathy and internal complications in diabetes mellitus. Int J Dermatol. 1998 Feb; 37(2):113-5.
Shemer A, Bergman R, Linn S, Kantor Y, Friedman-Birnbaum R. PMID: 9542665.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Central role of the adipocyte in insulin resistance. J Basic Clin Physiol Pharmacol. 1998; 9(2-4):205-21.
Bergman RN, Mittelman SD. PMID: 10212835.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. Am J Physiol. 1998 01; 274(1):E172-83.
Watanabe RM, Steil GM, Bergman RN. PMID: 9458763.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest. 1997 Dec 15; 100(12):3121-30.
Mittelman SD, Fu YY, Rebrin K, Steil G, Bergman RN. PMID: 9399959; PMCID: PMC508525.
View in:
PubMed Mentions:
23 Fields:
Translation:
Animals
-
Improved estimation of anaplerosis in heart using 13C NMR. Am J Physiol. 1997 12; 273(6):E1228-42.
Cohen DM, Bergman RN. PMID: 9435540.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol. Diabetes. 1997 Dec; 46(12):2044-8.
Saad MF, Steil GM, Riad-Gabriel M, Khan A, Sharma A, Boyadjian R, Jinagouda SD, Bergman RN. PMID: 9392494.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis: a theoretical evaluation of the single-compartment glucose distribution assumption. Diabetes. 1997 Nov; 46(11):1813-21.
Ni TC, Ader M, Bergman RN. PMID: 9356031.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes. 1997 Sep; 46(9):1521-5.
Hevener AL, Bergman RN, Donovan CM. PMID: 9287058.
View in:
PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. Am J Epidemiol. 1997 Aug 15; 146(4):315-21.
Mykkänen L, Haffner SM, Rönnemaa T, Bergman RN, Laakso M. PMID: 9270410.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Differences between the tolbutamide-boosted and the insulin-modified minimal model protocols. Diabetes. 1997 Jul; 46(7):1167-71.
Saad MF, Steil GM, Kades WW, Ayad MF, Elsewafy WA, Boyadjian R, Jinagouda SD, Bergman RN. PMID: 9200652.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Glucose effectiveness assessed under dynamic and steady state conditions. Comparability of uptake versus production components. J Clin Invest. 1997 Mar 15; 99(6):1187-99.
Ader M, Ni TC, Bergman RN. PMID: 9077526; PMCID: PMC507932.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab. 1997 Feb; 82(2):402-6.
Hofman PL, Cutfield WS, Robinson EM, Bergman RN, Menon RK, Sperling MA, Gluckman PD. PMID: 9024226.
View in:
PubMed Mentions:
77 Fields:
Translation:
Humans
-
New concepts in extracellular signaling for insulin action: the single gateway hypothesis. Recent Prog Horm Res. 1997; 52:359-85; discussion 385-7.
Bergman RN. PMID: 9238859.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) Am J Clin Nutr. 1997 Jan; 65(1):79-87.
Mayer-Davis EJ, Monaco JH, Hoen HM, Carmichael S, Vitolins MZ, Rewers MJ, Haffner SM, Ayad MF, Bergman RN, Karter AJ. PMID: 8988917.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites, and Hispanics with NIDDM: the Insulin Resistance Atherosclerosis Study. Diabetes. 1997 Jan; 46(1):63-9.
Haffner SM, Howard G, Mayer E, Bergman RN, Savage PJ, Rewers M, Mykkänen L, Karter AJ, Hamman R, Saad MF. PMID: 8971083.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Extracellular glucose distribution is not altered by insulin: analysis of plasma and interstitial L-glucose kinetics. Am J Physiol. 1996 Nov; 271(5 Pt 1):E855-64.
Steil GM, Richey J, Kim JK, Wi JK, Rebrin K, Bergman RN, Youn JH. PMID: 8944672.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Insulin sensitivity and abdominal obesity in African-American, Hispanic, and non-Hispanic white men and women. The Insulin Resistance and Atherosclerosis Study. Diabetes. 1996 Nov; 45(11):1547-55.
Karter AJ, Mayer-Davis EJ, Selby JV, D'Agostino RB, Haffner SM, Sholinsky P, Bergman R, Saad MF, Hamman RF. PMID: 8866560.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study. Stroke. 1996 Oct; 27(10):1744-9.
D'Agostino RB, Burke G, O'Leary D, Rewers M, Selby J, Savage PJ, Saad MF, Bergman RN, Howard G, Wagenknecht L, Haffner SM. PMID: 8841322.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care. 1996 Sep; 19(9):1018-30.
Best JD, Kahn SE, Ader M, Watanabe RM, Ni TC, Bergman RN. PMID: 8875104.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansAnimals
-
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest. 1996 Sep 01; 98(5):1195-209.
Clausen JO, Borch-Johnsen K, Ibsen H, Bergman RN, Hougaard P, Winther K, Pedersen O. PMID: 8787683; PMCID: PMC507542.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Toward an integrated phenotype in pre-NIDDM. Diabet Med. 1996 Sep; 13(9 Suppl 6):S67-77.
Bergman RN, Watanabe R, Rebrin K, Ader M, Steil G. PMID: 8894486.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest. 1996 Aug 01; 98(3):741-9.
Rebrin K, Steil GM, Mittelman SD, Bergman RN. PMID: 8698866; PMCID: PMC507484.
View in:
PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
-
Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Circulation. 1996 May 15; 93(10):1809-17.
Howard G, O'Leary DH, Zaccaro D, Haffner S, Rewers M, Hamman R, Selby JV, Saad MF, Savage P, Bergman R. PMID: 8635260.
View in:
PubMed Mentions:
151 Fields:
Translation:
Humans
-
Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest. 1996 Mar 15; 97(6):1497-503.
Steil GM, Ader M, Moore DM, Rebrin K, Bergman RN. PMID: 8617883; PMCID: PMC507210.
View in:
PubMed Mentions:
42 Fields:
Translation:
Animals
-
[Role of the liver as a glucose sensor in the integrated response to hypoglycemia]. Journ Annu Diabetol Hotel Dieu. 1996; 19-35.
Hamilton-Wessler M, Donovan CM, Bergman RN. PMID: 8965421.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes. 1995 Sep; 44(9):1038-45.
Rebrin K, Steil GM, Getty L, Bergman RN. PMID: 7657026.
View in:
PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
-
Insulin sensitivity accounts for glucose and lactate kinetics after intravenous glucose injection. Diabetes. 1995 Aug; 44(8):954-62.
Watanabe RM, Lovejoy J, Steil GM, DiGirolamo M, Bergman RN. PMID: 7622002.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Estimation of TCA cycle flux, aminotransferase flux, and anaplerosis in heart: validation with syntactic model. Am J Physiol. 1995 Mar; 268(3 Pt 1):E397-409.
Cohen DM, Bergman RN. PMID: 7900786.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
OOPSEG: a data smoothing program for quantitation and isolation of random measurement error. Comput Methods Programs Biomed. 1995 Jan; 46(1):67-77.
Bradley DC, Steil GM, Bergman RN. PMID: 7743783.
View in:
PubMed Mentions:
7 Fields:
-
Defects in carbohydrate metabolism in oral contraceptive users without apparent metabolic risk factors. J Clin Endocrinol Metab. 1994 Nov; 79(5):1277-83.
Watanabe RM, Azen CG, Roy S, Perlman JA, Bergman RN. PMID: 7962320.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCellsCTClinical Trials
-
Repeatability of insulin sensitivity and glucose effectiveness from the minimal model. Implications for study design. Diabetes. 1994 Nov; 43(11):1365-71.
Steil GM, Murray J, Bergman RN, Buchanan TA. PMID: 7926313.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
-
A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Insulin Resistance Atherosclerosis Study. Diabetes. 1994 Sep; 43(9):1114-21.
Saad MF, Anderson RL, Laws A, Watanabe RM, Kades WW, Chen YD, Sands RE, Pei D, Savage PJ, Bergman RN. PMID: 8070611.
View in:
PubMed Mentions:
68 Fields:
Translation:
Humans
-
Insulin sensitivity is not an independent determinant of plasma plasminogen activator inhibitor-1 activity. Arterioscler Thromb. 1994 Aug; 14(8):1264-71.
Mykkänen L, Rönnemaa T, Marniemi J, Haffner SM, Bergman R, Laakso M. PMID: 8049187.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes. 1994 Aug; 43(8):1052-60.
Hamilton-Wessler M, Bergman RN, Halter JB, Watanabe RM, Donovan CM. PMID: 8039600.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Is there a sex difference in the association of plasma insulin level and insulin sensitivity with serum lipids and lipoproteins? Metabolism. 1994 Apr; 43(4):523-8.
Mykkänen L, Haffner SM, Rönnemaa T, Bergman R, Leino A, Laakso M. PMID: 8159115.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol. 1994 Apr; 266(4 Pt 1):E540-7.
Kemnitz JW, Roecker EB, Weindruch R, Elson DF, Baum ST, Bergman RN. PMID: 8178974.
View in:
PubMed Mentions:
63 Fields:
Translation:
Animals
-
The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects. Diabetes. 1994 Apr; 43(4):587-92.
Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, et al. PMID: 8138065.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
SYNTAX: a rule-based stochastic simulation of the time-varying concentrations of positional isotopomers of metabolic intermediates. Comput Biomed Res. 1994 Apr; 27(2):130-47.
Cohen DM, Bergman RN. PMID: 8033538.
View in:
PubMed Mentions:
1 Fields:
-
Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proc Natl Acad Sci U S A. 1994 Mar 29; 91(7):2863-7.
Donovan CM, Hamilton-Wessler M, Halter JB, Bergman RN. PMID: 8146201; PMCID: PMC43471.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
Prediction of positional isotopomers of the citric acid cycle: the syntactic approach. Am J Physiol. 1994 Mar; 266(3 Pt 1):E341-50.
Cohen DM, Bergman RN. PMID: 7909408.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
The pathogenesis and clinical significance of xanthelasma palpebrarum. J Am Acad Dermatol. 1994 Feb; 30(2 Pt 1):236-42.
Bergman R. PMID: 8288783.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. Diabetes. 1994 Feb; 43(2):204-11.
Kemnitz JW, Elson DF, Roecker EB, Baum ST, Bergman RN, Meglasson MD. PMID: 8288044.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph. Diabetes. 1994 Feb; 43(2):180-90.
Poulin RA, Steil GM, Moore DM, Ader M, Bergman RN. PMID: 8288041.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. Am J Physiol. 1994 Jan; 266(1 Pt 1):E17-25.
Yang YJ, Hope ID, Ader M, Bergman RN. PMID: 8304440.
View in:
PubMed Mentions:
24 Fields:
Translation:
Animals
-
Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care. 1994 Jan; 17(1):30-6.
Wing RR, Blair EH, Bononi P, Marcus MD, Watanabe R, Bergman RN. PMID: 8112186.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCTClinical Trials
-
Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men. J Clin Invest. 1994 Jan; 93(1):10-6.
Castillo C, Bogardus C, Bergman R, Thuillez P, Lillioja S. PMID: 8282776; PMCID: PMC293712.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes. 1993 Nov; 42(11):1663-72.
Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, et al. PMID: 8405710.
View in:
PubMed Mentions:
446 Fields:
Translation:
Humans
-
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest. 1993 Oct; 92(4):1824-30.
Baura GD, Foster DM, Porte D, Kahn SE, Bergman RN, Cobelli C, Schwartz MW. PMID: 8408635; PMCID: PMC288346.
View in:
PubMed Mentions:
119 Fields:
Translation:
Animals
-
The influence of luteinizing hormone and insulin on sex steroids and sex hormone-binding globulin in the polycystic ovarian syndrome. Fertil Steril. 1993 Oct; 60(4):626-33.
Buyalos RP, Geffner ME, Watanabe RM, Bergman RN, Gornbein JA, Judd HL. PMID: 8405515.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Magnesium deficiency produces insulin resistance and increased thromboxane synthesis. Hypertension. 1993 Jun; 21(6 Pt 2):1024-9.
Nadler JL, Buchanan T, Natarajan R, Antonipillai I, Bergman R, Rude R. PMID: 8505087.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
Quantitation of measurement error with Optimal Segments: basis for adaptive time course smoothing. Am J Physiol. 1993 Jun; 264(6 Pt 1):E902-11.
Bradley DC, Steil GM, Bergman RN. PMID: 8333516.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue. Diabetes. 1993 May; 42(5):720-31.
Steil GM, Meador MA, Bergman RN. PMID: 8482429.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients. Diabetologia. 1993 Feb; 36(2):121-8.
Kruszynska YT, Harry DS, Bergman RN, McIntyre N. PMID: 8458526.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Socio-cultural determinants of child mortality in southern Peru: including some methodological considerations. Soc Sci Med. 1993 Feb; 36(3):317-31.
de Meer K, Bergman R, Kusner JS. PMID: 8426976.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes. 1993 Feb; 42(2):250-6.
Steil GM, Volund A, Kahn SE, Bergman RN. PMID: 8425661.
View in:
PubMed Mentions:
67 Fields:
Translation:
Humans
-
Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo. Diabetes. 1993 Feb; 42(2):296-306.
Bradley DC, Poulin RA, Bergman RN. PMID: 8093879.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
-
Effects of epinephrine on insulin secretion and action in humans. Interaction with aging. Diabetes. 1993 Feb; 42(2):307-15.
Morrow LA, Morganroth GS, Herman WH, Bergman RN, Halter JB. PMID: 8425666.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Differences in physical growth of Aymara and Quechua children living at high altitude in Peru. Am J Phys Anthropol. 1993 Jan; 90(1):59-75.
de Meer K, Bergman R, Kusner JS, Voorhoeve HW. PMID: 8470756.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
On insulin action in vivo: the single gateway hypothesis. Adv Exp Med Biol. 1993; 334:181-98.
Bergman RN, Bradley DC, Ader M. PMID: 8249682.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Hypertension and insulin resistance: role of sympathetic nervous system activity. Am J Physiol. 1992 Nov; 263(5 Pt 1):E935-42.
Supiano MA, Hogikyan RV, Morrow LA, Ortiz-Alonso FJ, Herman WH, Bergman RN, Halter JB. PMID: 1443127.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet. 1992 Oct 17; 340(8825):925-9.
Martin BC, Warram JH, Krolewski AS, Bergman RN, Soeldner JS, Kahn CR. PMID: 1357346.
View in:
PubMed Mentions:
295 Fields:
Translation:
Humans
-
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects. Diabetes. 1992 Jun; 41(6):750-9.
Lee A, Ader M, Bray GA, Bergman RN. PMID: 1587401.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome. Fertil Steril. 1992 Apr; 57(4):796-803.
Buyalos RP, Geffner ME, Bersch N, Judd HL, Watanabe RM, Bergman RN, Golde DW. PMID: 1555690.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Restoration of stable metabolic conditions during islet suppression in dogs. Am J Physiol. 1992 Apr; 262(4 Pt 1):E532-8.
Bradley DC, Bergman RN. PMID: 1348903.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Hepatic glucagon sensitivity and fasting glucose concentration in normal dogs. Am J Physiol. 1992 Apr; 262(4 Pt 1):E539-45.
Bradley DC, Bergman RN. PMID: 1566839.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. Am J Physiol. 1992 Apr; 262(4 Pt 1):E518-23.
Kahn SE, Bergman RN, Schwartz MW, Taborsky GJ, Porte D. PMID: 1566838.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
BASREP: a method for maintaining euglycemia during somatostatin suppression of pancreatic secretion. Comput Methods Programs Biomed. 1992 Mar; 37(2):107-15.
Pacini G, Ader M, Bergman RN. PMID: 1353714.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans. Eur J Clin Invest. 1992 Mar; 22(3):147-53.
Haffner SM, Stern MP, Watanabe RM, Bergman RN. PMID: 1582438.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues. Diabetes. 1992 Feb; 41(2):241-53.
Yang YJ, Hope I, Ader M, Poulin RA, Bergman RN. PMID: 1733816.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Modeling of insulin action in vivo. Annu Rev Physiol. 1992; 54:861-83.
Bergman RN, Steil GM, Bradley DC, Watanabe RM. PMID: 1562195.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Intravenous insulin infusion to simulate subcutaneous absorption. Bioavailability and metabolic sequelae. Diabetes Care. 1991 Nov; 14(11):1021-30.
Watanabe RM, Vølund A, Bergman RN. PMID: 1797482.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. J Clin Invest. 1991 Oct; 88(4):1272-81.
Schwartz MW, Bergman RN, Kahn SE, Taborsky GJ, Fisher LD, Sipols AJ, Woods SC, Steil GM, Porte D. PMID: 1918377; PMCID: PMC295596.
View in:
PubMed Mentions:
45 Fields:
Translation:
Animals
-
Glucose tolerance and insulin action in rats with renovascular hypertension. Hypertension. 1991 Sep; 18(3):341-7.
Buchanan TA, Sipos GF, Gadalah S, Yip KP, Marsh DJ, Hsueh W, Bergman RN. PMID: 1889847.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Deterioration in carbohydrate metabolism and lipoprotein changes induced by modern, high fat diet in Pima Indians and Caucasians. J Clin Endocrinol Metab. 1991 Jul; 73(1):156-65.
Swinburn BA, Boyce VL, Bergman RN, Howard BV, Bogardus C. PMID: 2045466.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCTClinical Trials
-
Conversion of oral glucose to lactate in dogs. Primary site and relative contribution to blood lactate. Diabetes. 1991 Jun; 40(6):738-47.
Youn JH, Bergman RN. PMID: 2040389.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Insulin action and metabolism in patients with head and neck cancer. Cancer. 1991 Jun 01; 67(11):2900-6.
Byerley LO, Heber D, Bergman RN, Dubria M, Chi J. PMID: 2025856.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes. 1991 Jan; 40(1):155-8.
Donovan CM, Halter JB, Bergman RN. PMID: 1849847.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
Neutral lipid storage disease with ichthyosis: serum apolipoprotein levels and cholesterol metabolism in monocyte-derived macrophages. J Inherit Metab Dis. 1991; 14(2):241-6.
Bergman R, Aviram M, Bitterman-Deutsch O, Oiknine Y, Shemer A, Srebnik A, Brook JG, Friedman-Birnbaum R. PMID: 1909403.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Search for the hypoglycemia receptor using the local irrigation approach. Adv Exp Med Biol. 1991; 291:185-96.
Donovan CM, Cane P, Bergman RN. PMID: 1656712.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab. 1990 Dec; 71(6):1508-18.
Welch S, Gebhart SS, Bergman RN, Phillips LS. PMID: 2229309.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Determination of portal insulin absorption from peritoneum via novel nonisotopic method. Diabetes. 1990 Nov; 39(11):1361-5.
Selam JL, Bergman RN, Raccah D, Jean-Didier N, Lozano J, Charles MA. PMID: 2227110.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Insulin resistance and acanthosis nigricans: evidence for a postbinding defect in vivo. Metabolism. 1990 Oct; 39(10):1006-11.
Cohen P, Harel C, Bergman R, Daoud D, Pam Z, Barzilai N, Armoni M, Karnieli E. PMID: 2215248.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. J Clin Endocrinol Metab. 1990 Oct; 71(4):994-1002.
Kahn SE, Klaff LJ, Schwartz MW, Beard JC, Bergman RN, Taborsky GJ, Porte D. PMID: 2205630.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol. 1990 Sep; 259(3 Pt 1):E378-83.
Schwartz MW, Sipols A, Kahn SE, Lattemann DF, Taborsky GJ, Bergman RN, Woods SC, Porte D. PMID: 2205107.
View in:
PubMed Mentions:
54 Fields:
Translation:
Animals
-
Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism. 1990 Aug; 39(8):842-7.
Haffner SM, Stern MP, Dunn J, Mobley M, Blackwell J, Bergman RN. PMID: 2198435.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am J Physiol. 1990 Jun; 258(6 Pt 1):E1020-32.
Ader M, Bergman RN. PMID: 2193527.
View in:
PubMed Mentions:
41 Fields:
Translation:
Animals
-
Enhancement of hepatic glycogen by gluconeogenic precursors: substrate flux or metabolic control? Am J Physiol. 1990 Jun; 258(6 Pt 1):E899-906.
Youn JH, Bergman RN. PMID: 2193531.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
The modified minimal model: application to measurement of insulin sensitivity in children. J Clin Endocrinol Metab. 1990 Jun; 70(6):1644-50.
Cutfield WS, Bergman RN, Menon RK, Sperling MA. PMID: 2189887.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. Am J Obstet Gynecol. 1990 Apr; 162(4):1008-14.
Buchanan TA, Metzger BE, Freinkel N, Bergman RN. PMID: 2183610.
View in:
PubMed Mentions:
89 Fields:
Translation:
Humans
-
The role of the transcapillary insulin transport in the efficiency of insulin action: studies with glucose clamps and the minimal model. Horm Metab Res Suppl. 1990; 24:49-56.
Bergman RN, Yang YJ, Hope ID, Ader M. PMID: 2272626.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes. 1989 Dec; 38(12):1512-27.
Bergman RN. PMID: 2684710.
View in:
PubMed Mentions:
212 Fields:
Translation:
HumansAnimals
-
Impact of computer simulation on diabetes research and practice. Diabetes Care. 1989 Nov-Dec; 12(10):748-9.
Bergman RN, Buchanan TA. PMID: 2612309.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Insulin transport across capillaries is rate limiting for insulin action in dogs. J Clin Invest. 1989 Nov; 84(5):1620-8.
Yang YJ, Hope ID, Ader M, Bergman RN. PMID: 2681272; PMCID: PMC304028.
View in:
PubMed Mentions:
87 Fields:
Translation:
Animals
-
Prehepatic beta-cell secretion during the intravenous glucose tolerance test in humans: application of a combined model of insulin and C-peptide kinetics. J Clin Endocrinol Metab. 1989 Oct; 69(4):790-7.
Watanabe RM, Volund A, Roy S, Bergman RN. PMID: 2674187.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Assessment of insulin sensitivity in vivo: a critical review. Diabetes Metab Rev. 1989 Aug; 5(5):411-29.
Bergman RN, Hope ID, Yang YJ, Watanabe RM, Meador MA, Youn JH, Ader M. PMID: 2667927.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
-
Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes. 1989 May; 38(5):562-8.
Kahn SE, Beard JC, Schwartz MW, Ward WK, Ding HL, Bergman RN, Taborsky GJ, Porte D. PMID: 2653928.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Glucose phosphorylation is not rate limiting for accumulation of glycogen from glucose in perfused livers from fasted rats. J Biol Chem. 1989 Jan 05; 264(1):168-72.
Youn JH, Ader M, Bergman RN. PMID: 2642472.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Response to deep hypoglycemia does not involve glucoreceptors in carotid perfused tissue. Am J Physiol. 1988 Nov; 255(5 Pt 1):E680-7.
Cane P, Haun CK, Evered J, Youn JH, Bergman RN. PMID: 2847539.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Insulin resistance and beta-cell dysfunction in aging: the importance of dietary carbohydrate. J Clin Endocrinol Metab. 1988 Nov; 67(5):951-7.
Chen M, Bergman RN, Porte D. PMID: 3053750.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCTClinical Trials
-
Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes. J Clin Endocrinol Metab. 1988 Oct; 67(4):785-92.
McCulloch DK, Raghu PK, Johnston C, Klaff LJ, Kahn SE, Beard JC, Ward WK, Benson EA, Koerker DJ, Bergman RN, et al. PMID: 3047163.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes. 1988 Aug; 37(8):1025-34.
Finegood DT, Bergman RN, Vranic M. PMID: 3292323.
View in:
PubMed Mentions:
32 Fields:
Translation:
Animals
-
OPSEG: a general routine for smoothing and interpolating discrete biological data. Comput Methods Programs Biomed. 1988 May-Jun; 26(3):289-99.
Finegood DT, Thomaseth K, Pacini G, Bergman RN. PMID: 3383567.
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PubMed Mentions:
2 Fields:
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Modeling in nutrition and metabolism. Prog Food Nutr Sci. 1988; 12(3):211-25.
Bergman RN. PMID: 2855276.
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Translation:
Humans
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Modified protocols improve insulin sensitivity estimation using the minimal model. Am J Physiol. 1987 Dec; 253(6 Pt 1):E595-602.
Yang YJ, Youn JH, Bergman RN. PMID: 2892414.
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PubMed Mentions:
41 Fields:
Translation:
Animals
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Insulin sensitivity in the intact organism. Baillieres Clin Endocrinol Metab. 1987 Nov; 1(4):879-910.
Ader M, Bergman RN. PMID: 3330434.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Patterns of glycogen turnover in liver characterized by computer modeling. Am J Physiol. 1987 Oct; 253(4 Pt 1):E360-9.
Youn JH, Bergman RN. PMID: 3661699.
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PubMed Mentions:
3 Fields:
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Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics. Diabetes. 1987 Oct; 36(10):1195-202.
Vølund A, Polonsky KS, Bergman RN. PMID: 2888696.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Fructose effect to suppress hepatic glycogen degradation. J Biol Chem. 1987 Aug 25; 262(24):11470-7.
Youn JH, Kaslow HR, Bergman RN. PMID: 3114246.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes. 1987 Aug; 36(8):914-24.
Finegood DT, Bergman RN, Vranic M. PMID: 3297886.
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PubMed Mentions:
149 Fields:
Translation:
Animals
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Beta-cell function and insulin sensitivity in nondiabetic HLA-identical siblings of insulin-dependent diabetics. Diabetes. 1987 Jul; 36(7):829-37.
Johnston C, Raghu P, McCulloch DK, Beard JC, Ward WK, Klaff LJ, McKnight B, Bergman RN, Palmer JP. PMID: 3556281.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest. 1987 Mar; 79(3):790-800.
Bergman RN, Prager R, Volund A, Olefsky JM. PMID: 3546379; PMCID: PMC424201.
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PubMed Mentions:
149 Fields:
Translation:
Humans
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Recombinant deoxyribonucleic acid-derived 22K- and 20K-human growth hormone generate equivalent diabetogenic effects during chronic infusion in dogs. Endocrinology. 1987 Feb; 120(2):725-31.
Ader M, Agajanian T, Finegood DT, Bergman RN. PMID: 3542508.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Synergism of glucose and fructose in net glycogen synthesis in perfused rat livers. J Biol Chem. 1986 Dec 05; 261(34):15960-9.
Youn JH, Youn MS, Bergman RN. PMID: 3023336.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Pathophysiology of malnutrition in the adult cancer patient. Cancer. 1986 Oct 15; 58(8 Suppl):1867-73.
Heber D, Byerley LO, Chi J, Grosvenor M, Bergman RN, Coleman M, Chlebowski RT. PMID: 3093049.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed. 1986 Oct; 23(2):113-22.
Pacini G, Bergman RN. PMID: 3640682.
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PubMed Mentions:
166 Fields:
Translation:
Humans
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Oscillations enhance the efficiency and stability of glucose disposal. Am J Physiol. 1986 May; 250(5 Pt 1):E576-82.
Marsh BD, Marsh DJ, Bergman RN. PMID: 3518489.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes. 1986 Mar; 35(3):362-9.
Beard JC, Bergman RN, Ward WK, Porte D. PMID: 3512346.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimals
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Putative hypothalamic glucoreceptors play no essential role in the response to moderate hypoglycemia. Diabetes. 1986 Mar; 35(3):268-77.
Cane P, Artal R, Bergman RN. PMID: 3005093.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Importance of glucose per se to intravenous glucose tolerance. Comparison of the minimal-model prediction with direct measurements. Diabetes. 1985 Nov; 34(11):1092-103.
Ader M, Pacini G, Yang YJ, Bergman RN. PMID: 2864297.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Reduced insulin sensitivity in nondiabetic, HLA-identical siblings of insulin-dependent diabetic subjects. Diabetes. 1985 Oct; 34(10):991-4.
Raghu P, Johnston C, Beard JC, Bergman R, McCulloch DK, Palmer JP. PMID: 4043555.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Effect of thyroid hormone excess on action, secretion, and metabolism of insulin in humans. Am J Physiol. 1985 May; 248(5 Pt 1):E593-601.
Dimitriadis G, Baker B, Marsh H, Mandarino L, Rizza R, Bergman R, Haymond M, Gerich J. PMID: 3887944.
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PubMed Mentions:
61 Fields:
Translation:
Humans
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Diminished in vitro responsiveness of circulating erythroid progenitor cells to insulin as an indicator of insulin resistance. J Clin Endocrinol Metab. 1985 Jan; 60(1):103-8.
Geffner ME, Kaplan SA, Bersch N, Lippe BM, Scott ML, Bergman RN, Golde DW. PMID: 3880558.
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Translation:
HumansCells
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Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function. J Clin Endocrinol Metab. 1985 Jan; 60(1):13-20.
Chen M, Bergman RN, Pacini G, Porte D. PMID: 3880560.
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PubMed Mentions:
69 Fields:
Translation:
Humans
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Assessment of insulin sensitivity in vivo. Endocr Rev. 1985; 6(1):45-86.
Bergman RN, Finegood DT, Ader M. PMID: 3884329.
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PubMed Mentions:
199 Fields:
Translation:
HumansAnimals
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Extrapancreatic effect of somatostatin infusion to increase glucose clearance. Am J Physiol. 1984 Sep; 247(3 Pt 1):E370-9.
Bergman RN, Ader M, Finegood DT, Pacini G. PMID: 6148014.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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The insulin sensitivity index. Correlation in dogs between values determined from the intravenous glucose tolerance test and the euglycemic glucose clamp. Diabetes. 1984 Apr; 33(4):362-8.
Finegood DT, Pacini G, Bergman RN. PMID: 6368293.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol. 1983 May; 244(5):E472-9.
Finegood DT, Bergman RN. PMID: 6846533.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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PACBERG: an adaptive program for controlling the blood sugar. Comput Programs Biomed. 1983 Feb-Apr; 16(1-2):13-20.
Pacini G, Bergman RN. PMID: 6342930.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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A minimal-model-based glucose clamp yielding insulin sensitivity independent of glycemia. Diabetes. 1982 May; 31(5 Pt 1):432-41.
Pacini G, Finegood DT, Bergman RN. PMID: 6759258.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Intraportal glucose infusion matched to oral glucose absorption. Lack of evidence for "gut factor" involvement in hepatic glucose storage. Diabetes. 1982 Jan; 31(1):27-35.
Bergman RN, Beir JR, Hourigan PM. PMID: 7152123.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest. 1981 Dec; 68(6):1456-67.
Bergman RN, Phillips LS, Cobelli C. PMID: 7033284; PMCID: PMC370948.
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PubMed Mentions:
354 Fields:
Translation:
Humans
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Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog. Diabetes. 1980 Dec; 29(12):979-90.
Toffolo G, Bergman RN, Finegood DT, Bowden CR, Cobelli C. PMID: 7002673.
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PubMed Mentions:
44 Fields:
Translation:
Animals
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Cause of glucose oscillations during glucose infusion: periodic variation in glucose uptake. Am J Physiol. 1980 Apr; 238(4):E395-407.
Bowden CR, Bergman RN, Marsh DJ. PMID: 6990778.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Effect of insulin, glucose, and 2-deoxy-glucose infusion into the third cerebral ventricle of conscious dogs on plasma insulin, glucose, and free fatty acids. Diabetes. 1980 Apr; 29(4):278-83.
Taborsky GJ, Bergman RN. PMID: 6987116.
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Translation:
Animals
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Minimal modeling, partition analysis, and the estimation of insulin sensitivity. Fed Proc. 1980 Jan; 39(1):110-5.
Bergman RN, Cobelli C. PMID: 6985867.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Quantitative estimation of insulin sensitivity. Am J Physiol. 1979 Jun; 236(6):E667-77.
Bergman RN, Ider YZ, Bowden CR, Cobelli C. PMID: 443421.
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PubMed Mentions:
414 Fields:
Translation:
Animals
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Caval occlusion technique for hepatic venous sampling: a new approach to estimating splanchnic substrate balance in conscious dogs. Metabolism. 1979 May; 28(5):562-7.
Bowden CR, Bergman RN. PMID: 449697.
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PubMed Mentions: Fields:
Translation:
Animals
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Glucagon-stimulated glycogenolysis: time-dependent sensitivity to insulin. Am J Physiol. 1979 Mar; 236(3):E246-54.
El-Refai M, Bergman RN. PMID: 426055.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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'Non-starters' in schools for registered nurses in Israel--1975-1976. Int J Nurs Stud. 1979; 16(2):151-7.
Bergman R, Rotenberg A, Ron R, Sharon R, Zwanger L. PMID: 255454.
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Translation:
Humans
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Neurohypophyseal hormone-responsive renal adenylate cyclase. IV. A random-hit matrix model for coupline in a hormone-sensitive adenylate cyclase system. J Biol Chem. 1978 May 10; 253(9):3238-50.
Bergman RN, Hechter O. PMID: 641067.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Integrated control of hepatic glucose metabolism. Fed Proc. 1977 Feb; 36(2):265-70.
Bergman RN. PMID: 190047.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Simulation study of control of hepatic glycogen synthesis by glucose and insulin. Am J Physiol. 1976 Nov; 231(5 Pt. 1):1608-19.
El-Refai M, Bergman RN. PMID: 187069.
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PubMed Mentions:
9 Fields:
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Dynamic control of hepatic glucose metabolism: Studies by experiment and computer simulation. Ann Biomed Eng. 1975 Dec; 3(4):411-32.
Bergman RN, Refai ME. PMID: 176905.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Interaction of insulin and glucose in the control of hepatic glucose balance. Am J Physiol. 1974 Dec; 227(6):1314-22.
Bergman RN, Bucolo RJ. PMID: 4440776.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Dynamics of glucose autoregulation in the isolated, blood-perfused canine liver. Am J Physiol. 1974 Jul; 227(1):209-17.
Bucolo RJ, Bergman RN, Marsh DJ, Yates FE. PMID: 4843372.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Fluctuations of plasma glucose and insulin in conscious dogs receiving glucose infusions. Am J Physiol. 1974 Apr; 226(4):910-9.
Ookhtens M, Marsh DJ, Smith SW, Bergman RN, Yates FE. PMID: 4823053.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Measurement error inherent in the determination of hepatic glucose balance. J Appl Physiol. 1974 Feb; 36(2):269-73.
Bergman RN, Azen SP. PMID: 4811391.
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PubMed Mentions:
1 Fields:
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Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas. Am J Physiol. 1973 Aug; 225(2):481-6.
Bergman RN, Miller RE. PMID: 4722412.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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The pilot gland approach to the study of insulin secretory dynamics. Recent Prog Horm Res. 1971; 27:583-605 passim.
Bergman RN, Urquhart J. PMID: 4946134.
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PubMed Mentions:
14 Fields:
Translation:
Animals