Roberta A Gottlieb

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of the Dynamic Proteome after Ischemic Injury
    NIH R01HL144509Feb 1, 2019 - Jan 31, 2023
    Role: Co-Principal Investigator
    Mitochondrial Turnover in the Human Heart
    NIH R01HL132075Dec 15, 2016 - Nov 30, 2020
    Role: Principal Investigator
    Mitochondrial Quality in Cardioprotection: Overcoming Co-Morbidities
    NIH P01HL112730Jul 1, 2013 - Jun 30, 2019
    Role: Principal Investigator
    In Vivo Imaging of Heart Disease and Host-Pathogen Processes
    NIH S10RR025596Mar 18, 2010 - Mar 17, 2012
    Role: Principal Investigator
    Juvenile mouse model of delayed anthracycline cardiotoxicity
    NIH R01HL092136Dec 19, 2008 - Feb 28, 2014
    Role: Principal Investigator
    Subcellular Regulation of Autophagic Flux in Cardiomyocytes and the Heart
    NIH R01AG033283Mar 15, 2008 - Aug 28, 2013
    Role: Principal Investigator
    Cytochrome P450 in Reperfusion Injury
    NIH R01HL071091Dec 1, 2003 - Nov 30, 2008
    Role: Principal Investigator
    Bid-Mediated Cytochrome c Release from Mitochondria
    NIH R01AG021568Aug 1, 2003 - Jul 31, 2009
    Role: Principal Investigator
    MITOCHONDRIAL ROLE IN CASPASE PROCESSING AND ACTIVATION
    NIH R01HL061518Jan 1, 1999 - Dec 31, 2004
    Role: Principal Investigator
    Rescue and Role of Complex I in myocardial ischemic injury
    NIH R01HL060590Sep 1, 1998 - May 31, 2013
    Role: Principal Investigator
    MECHANISMS OF APOPTOSIS IN BLOOD CELLS
    NIH R01AG013501Feb 10, 1996 - Jan 31, 2002
    Role: Principal Investigator
    PROGRAMMED CELL DEATH IN NEUTROPHILS
    NIH K08AI001345Apr 1, 1995 - Mar 31, 1998
    Role: Principal Investigator
    Autophagy, Adenosine and Pyruvate Protection During Heart Surgery
    NIH R01HL034579Jul 1, 1985 - Aug 31, 2014
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles. PLoS Pathog. 2022 08; 18(8):e1010350. Sawaged S, Mota T, Piplani H, Thakur R, Lall D, McCabe E, Seo S, Sutterwala FS, Feuer R, Gottlieb RA, Sin J. PMID: 36044516; PMCID: PMC9469980.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Calcium, mitochondria and the initiation of acute pancreatitis. Pancreatology. 2022 Nov; 22(7):838-845. Pandol SJ, Gottlieb RA. PMID: 35941013.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c. J Biol Chem. 2022 07; 298(7):102050. Dogan AE, Hamid SM, Yildirim AD, Yildirim Z, Sen G, Riera CE, Gottlieb RA, Erbay E. PMID: 35598827; PMCID: PMC9218515.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling. Matrix Biol. 2022 06; 110:40-59. Huang C, Sharma A, Thakur R, Rai D, Katiki M, Germano JF, Song Y, Singh S, Sin J, Sengstock D, Andres AM, Murali R, Mentzer RM, Gottlieb RA, Piplani H. PMID: 35470068; PMCID: PMC10234622.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    5. Autophagy deficiency abolishes liver mitochondrial DNA segregation. Autophagy. 2022 Oct; 18(10):2397-2408. Tostes K, Dos Santos AC, Alves LO, Bechara LRG, Marascalchi R, Macabelli CH, Grejo MP, Festuccia WT, Gottlieb RA, Ferreira JCB, Chiaratti MR. PMID: 35220898; PMCID: PMC9542960.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nat Commun. 2022 01 28; 13(1):557. Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk JE, Mato JM, Lu SC. PMID: 35091576; PMCID: PMC8799735.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Attenuation of Adverse Postinfarction Left Ventricular Remodeling with Empagliflozin Enhances Mitochondria-Linked Cellular Energetics and Mitochondrial Biogenesis. Int J Mol Sci. 2021 Dec 31; 23(1). Song Y, Huang C, Sin J, Germano JF, Taylor DJR, Thakur R, Gottlieb RA, Mentzer RM, Andres AM. PMID: 35008865; PMCID: PMC8745294.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    8. Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 09 22; 6(18). Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. PMID: 34403365; PMCID: PMC8492304.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. Myocardial ultrastructure can augment genetic testing for sporadic dilated cardiomyopathy with initial heart failure. ESC Heart Fail. 2021 12; 8(6):5178-5191. Saito T, Sato NS, Mozawa K, Adachi A, Sasaki Y, Nakamura K, Oka E, Otsuka T, Kodani E, Asai K, Mizuno K, Shimizu W, Gottlieb RA. PMID: 34486814; PMCID: PMC8712817.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Characterizing opioid-involved overdose risk in local communities: An opioid overdose vulnerability assessment across Indiana, 2017. Prev Med Rep. 2021 Dec; 24:101538. Sawyer JL, Shrestha S, Pustz JC, Gottlieb R, Nichols D, Van Handel M, Lingwall C, Stopka TJ. PMID: 34976612; PMCID: PMC8683947.
      View in: PubMed   Mentions: 2  
    11. Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy. Int J Mol Sci. 2021 Aug 13; 22(16). de Freitas Germano J, Sharma A, Stastna M, Huang C, Aniag M, Aceves A, Van Eyk JE, Mentzer RM, Piplani H, Andres AM, Gottlieb RA. PMID: 34445425; PMCID: PMC8395861.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Hypothermia promotes mitochondrial elongation In cardiac cells via inhibition of Drp1. Cryobiology. 2021 10; 102:42-55. Taylor D, Germano J, Song Y, Hadj-Moussa H, Marek-Iannucci S, Dhanji R, Sin J, Czer LSC, Storey KB, Gottlieb RA. PMID: 34331901.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    13. Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress. Mol Cancer Res. 2021 08; 19(8):1375-1388. Thomas TM, Miyaguchi K, Edwards LA, Wang H, Wollebo H, Aiguo L, Murali R, Wang Y, Braas D, Michael JS, Andres AM, Zhang M, Khalili K, Gottlieb RA, Perez JM, Yu JS. PMID: 33863814; PMCID: PMC8349847.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, et al. PMID: 33634751; PMCID: PMC7996087.
      View in: PubMed   Mentions: 726     Fields:    Translation:HumansAnimalsCells
    15. At the heart of mitochondrial quality control: many roads to the top. Cell Mol Life Sci. 2021 Apr; 78(8):3791-3801. Gottlieb RA, Piplani H, Sin J, Sawaged S, Hamid SM, Taylor DJ, de Freitas Germano J. PMID: 33544154; PMCID: PMC8106602.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    16. Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. PMID: 33361152; PMCID: PMC7817159.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    17. Acute myocardial infarction secondary to mucormycosis after lung transplantation. IDCases. 2021; 23:e01019. Naik CA, Mathai SK, Sandkovsky US, Ausloos KA, Guileyardo JM, Schwartz G, Mason DP, Gottlieb R, Grazia TJ. PMID: 33376674; PMCID: PMC7758357.
      View in: PubMed   Mentions: 1  
    18. Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation. Front Physiol. 2020; 11:950. Wang Q, Wang Z, Xu M, Tu W, Hsin IF, Stotland A, Kim JH, Liu P, Naiki M, Gottlieb RA, Seki E. PMID: 32848877; PMCID: PMC7424056.
      View in: PubMed   Mentions: 1  
    19. Sensing Protein Quality in Cardiac Myocytes p62 Triggers a Lysosomal Response. Circ Res. 2020 07 31; 127(4):519-521. Diwan A, Gottlieb RA. PMID: 32762530; PMCID: PMC7416846.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    20. Parkin, an E3 ubiquitin ligase, enhances airway mitochondrial DNA release and inflammation. Thorax. 2020 09; 75(9):717-724. Dimasuay KG, Schaunaman N, Martin RJ, Pavelka N, Kolakowski C, Gottlieb RA, Holguin F, Chu HW. PMID: 32499407.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    21. Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover. Sci Rep. 2020 05 19; 10(1):8284. Germano JF, Huang C, Sin J, Song Y, Tucker KC, Taylor DJR, Saadaeijahromi H, Stotland A, Piplani H, Gottlieb RA, Mentzer RM, Andres AM. PMID: 32427925; PMCID: PMC7237417.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    22. Minimal Invasive Pericardial Perfusion Model in Swine: A Translational Model for Cardiac Remodeling After Ischemia/Reperfusion Injury. Front Physiol. 2020; 11:346. Marek-Iannucci S, Thomas A, Gottlieb RA. PMID: 32390863; PMCID: PMC7188781.
      View in: PubMed   Mentions:
    23. MitoPlex: A targeted multiple reaction monitoring assay for quantification of a curated set of mitochondrial proteins. J Mol Cell Cardiol. 2020 05; 142:1-13. Stotland AB, Spivia W, Orosco A, Andres AM, Gottlieb RA, Van Eyk JE, Parker SJ. PMID: 32234390; PMCID: PMC7347090.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    24. β2 -adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy. FASEB J. 2020 04; 34(4):5628-5641. Campos JC, Baehr LM, Ferreira ND, Bozi LHM, Andres AM, Ribeiro MAC, Gottlieb RA, Bodine SC, Ferreira JCB. PMID: 32112488.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    25. Decrease of Cardiac Parkin Protein in Obese Mice. Front Cardiovasc Med. 2019; 6:191. Thomas A, Marek-Iannucci S, Tucker KC, Andres AM, Gottlieb RA. PMID: 32039238; PMCID: PMC6984192.
      View in: PubMed   Mentions: 8  
    26. Pushing the Heart Over a KLF(15). J Am Coll Cardiol. 2019 10 08; 74(14):1820-1822. Gottlieb RA, Bhowmick NA. PMID: 31582142.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    27. Matrix-guided control of mitochondrial function in cardiac myocytes. Acta Biomater. 2019 10 01; 97:281-295. Lyra-Leite DM, Andres AM, Cho N, Petersen AP, Ariyasinghe NR, Kim SS, Gottlieb RA, McCain ML. PMID: 31401347; PMCID: PMC6801042.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    28. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochim Biophys Acta Mol Basis Dis. 2019 11 01; 1865(11):165530. Piplani H, Marek-Iannucci S, Sin J, Hou J, Takahashi T, Sharma A, de Freitas Germano J, Waldron RT, Saadaeijahromi H, Song Y, Gulla A, Wu B, Lugea A, Andres AM, Gaisano HY, Gottlieb RA, Pandol SJ. PMID: 31398467.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    29. Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury. Sci Rep. 2019 07 10; 9(1):10001. Marek-Iannucci S, Thomas A, Hou J, Crupi A, Sin J, Taylor DJ, Czer LS, Esmailian F, Mentzer RM, Andres AM, Gottlieb RA. PMID: 31292486; PMCID: PMC6620356.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    30. Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression. Hepatology. 2019 12; 70(6):2018-2034. Murray B, Peng H, Barbier-Torres L, Robinson AE, Li TWH, Fan W, Tomasi ML, Gottlieb RA, Van Eyk J, Lu Z, Martínez-Chantar ML, Liangpunsakul S, Skill NJ, Mato JM, Lu SC. PMID: 31077594; PMCID: PMC6842664.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    31. Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis. J Am Coll Cardiol. 2019 03 19; 73(10):1149-1169. Onat UI, Yildirim AD, Tufanli Ö, Çimen I, Kocatürk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. PMID: 30871699; PMCID: PMC6424590.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    32. Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis. JCI Insight. 2019 Feb 07; 4(3). Matundan HH, Sin J, Rivas MN, Fishbein MC, Lehman TJ, Chen S, Gottlieb RA, Crother TR, Abe M, Arditi M. PMID: 30728329; PMCID: PMC6413776.
      View in: PubMed   Mentions: 9     Fields:    
    33. Retraction Note: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nat Commun. 2019 Feb 02; 10(1):645. Rajamani U, Gross AR, Ocampo C, Andres AM, Gottlieb RA, Sareen D. PMID: 30712056; PMCID: PMC6359997.
      View in: PubMed   Mentions:    Fields:    
    34. Coxsackievirus B infection induces the extracellular release of miR-590-5p, a proviral microRNA. Virology. 2019 03; 529:169-176. Germano JF, Sawaged S, Saadaeijahromi H, Andres AM, Feuer R, Gottlieb RA, Sin J. PMID: 30711774; PMCID: PMC6382511.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    35. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging (Albany NY). 2018 11 18; 10(11):3327-3352. Crupi AN, Nunnelee JS, Taylor DJ, Thomas A, Vit JP, Riera CE, Gottlieb RA, Goodridge HS. PMID: 30449736; PMCID: PMC6286850.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    36. Sex differences in ischemic heart disease and heart failure biomarkers. Biol Sex Differ. 2018 09 17; 9(1):43. Sobhani K, Nieves Castro DK, Fu Q, Gottlieb RA, Van Eyk JE, Noel Bairey Merz C. PMID: 30223899; PMCID: PMC6142320.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    37. Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion. J Vis Exp. 2018 08 29; (138). Stastna M, Thomas A, Germano J, Pourpirali S, Van Eyk JE, Gottlieb RA. PMID: 30222143; PMCID: PMC6231915.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    38. Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming. J Clin Invest. 2018 10 01; 128(10):4472-4484. Mishra R, Haldar S, Placencio V, Madhav A, Rohena-Rivera K, Agarwal P, Duong F, Angara B, Tripathi M, Liu Z, Gottlieb RA, Wagner S, Posadas EM, Bhowmick NA. PMID: 30047926; PMCID: PMC6159981.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    39. Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1112-H1126. Parker SJ, Stotland A, MacFarlane E, Wilson N, Orosco A, Venkatraman V, Madrid K, Gottlieb R, Dietz HC, Van Eyk JE. PMID: 30004239; PMCID: PMC6335018.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. Antagonizing CD105 enhances radiation sensitivity in prostate cancer. Oncogene. 2018 08; 37(32):4385-4397. Madhav A, Andres A, Duong F, Mishra R, Haldar S, Liu Z, Angara B, Gottlieb R, Zumsteg ZS, Bhowmick NA. PMID: 29717261; PMCID: PMC6085281.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    41. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 2018 05 03; 22(5):698-712.e9. Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D. PMID: 29681516; PMCID: PMC6398951.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    42. Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming. J Immunol. 2018 05 01; 200(9):3047-3052. Elliott EI, Miller AN, Banoth B, Iyer SS, Stotland A, Weiss JP, Gottlieb RA, Sutterwala FS, Cassel SL. PMID: 29602772; PMCID: PMC5916517.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    43. Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy. Stem Cell Reports. 2018 03 13; 10(3):942-955. Aminzadeh MA, Rogers RG, Fournier M, Tobin RE, Guan X, Childers MK, Andres AM, Taylor DJ, Ibrahim A, Ding X, Torrente A, Goldhaber JM, Lewis M, Gottlieb RA, Victor RA, Marbán E. PMID: 29478899; PMCID: PMC5918344.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    44. Periodontal disease and its connection to systemic biomarkers of cardiovascular disease in young American Indian/Alaskan natives. J Periodontol. 2018 02; 89(2):219-227. Delange N, Lindsay S, Lemus H, Finlayson TL, Kelley ST, Gottlieb RA. PMID: 29520828; PMCID: PMC6242269.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    45. Physiological Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand. Circ Res. 2018 01 19; 122(2):282-295. Coronado M, Fajardo G, Nguyen K, Zhao M, Kooiker K, Jung G, Hu DQ, Reddy S, Sandoval E, Stotland A, Gottlieb RA, Bernstein D. PMID: 29233845; PMCID: PMC5775047.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    46. Coxsackievirus B Escapes the Infected Cell in Ejected Mitophagosomes. J Virol. 2017 12 15; 91(24). Sin J, McIntyre L, Stotland A, Feuer R, Gottlieb RA. PMID: 28978702; PMCID: PMC5709598.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    47. Delivering Instant Heat: Shocking the Heart. J Am Coll Cardiol. 2017 09 19; 70(12):1493-1495. Gottlieb RA. PMID: 28911513.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nat Commun. 2017 08 09; 8(1):219. Rajamani U, Gross AR, Ocampo C, Andres AM, Gottlieb RA, Sareen D. PMID: 28794470; PMCID: PMC5550485.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    49. Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy. 2017 Aug 03; 13(8):1304-1317. Campos JC, Queliconi BB, Bozi LHM, Bechara LRG, Dourado PMM, Andres AM, Jannig PR, Gomes KMS, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB. PMID: 28598232; PMCID: PMC5584854.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    50. Autophagosome formation is required for cardioprotection by chloramphenicol. Life Sci. 2017 Oct 01; 186:11-16. Giricz Z, Varga ZV, Koncsos G, Nagy CT, Görbe A, Mentzer RM, Gottlieb RA, Ferdinandy P. PMID: 28778689; PMCID: PMC6242268.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    51. Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment. Am J Physiol Heart Circ Physiol. 2017 Oct 01; 313(4):H757-H767. Lyra-Leite DM, Andres AM, Petersen AP, Ariyasinghe NR, Cho N, Lee JA, Gottlieb RA, McCain ML. PMID: 28733449; PMCID: PMC5668604.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    52. Exploring ribosome composition and newly synthesized proteins through proteomics and potential biomedical applications. Expert Rev Proteomics. 2017 06; 14(6):529-543. Stastna M, Gottlieb RA, Van Eyk JE. PMID: 28532181; PMCID: PMC6242274.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    53. Mitophagy and Mitochondrial Quality Control Mechanisms in the Heart. Curr Pathobiol Rep. 2017 Jun; 5(2):161-169. Gottlieb RA, Thomas A. PMID: 29082112; PMCID: PMC5656254.
      View in: PubMed   Mentions: 22  
    54. Myocardial stress and autophagy: mechanisms and potential therapies. Nat Rev Cardiol. 2017 07; 14(7):412-425. Delbridge LMD, Mellor KM, Taylor DJ, Gottlieb RA. PMID: 28361977; PMCID: PMC6245608.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    55. Hypercholesterolemia downregulates autophagy in the rat heart. Lipids Health Dis. 2017 Mar 23; 16(1):60. Giricz Z, Koncsos G, Rajtík T, Varga ZV, Baranyai T, Csonka C, Szobi A, Adameová A, Gottlieb RA, Ferdinandy P. PMID: 28330474; PMCID: PMC5363032.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    56. Parkin-mediated mitophagy is downregulated in browning of white adipose tissue. Obesity (Silver Spring). 2017 04; 25(4):704-712. Taylor D, Gottlieb RA. PMID: 28240819; PMCID: PMC5373982.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    57. Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass. JCI Insight. 2017 02 23; 2(4):e89303. Andres AM, Tucker KC, Thomas A, Taylor DJ, Sengstock D, Jahania SM, Dabir R, Pourpirali S, Brown JA, Westbrook DG, Ballinger SW, Mentzer RM, Gottlieb RA. PMID: 28239650; PMCID: PMC5313075.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    58. Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy. PLoS One. 2016; 11(12):e0167678. Queliconi BB, Kowaltowski AJ, Gottlieb RA. PMID: 27973540; PMCID: PMC5156406.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    59. Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis. Circ Res. 2016 Sep 02; 119(6):e76-90. Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S, Arditi M. PMID: 27384322; PMCID: PMC5010464.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    60. Correction: The Impact of Juvenile Coxsackievirus Infection on Cardiac Progenitor Cells and Postnatal Heart Development. PLoS Pathog. 2016 May; 12(5):e1005673. Sin J, Puccini JM, Huang C, Konstandin MH, Gilbert PE, Sussman MA, Gottlieb RA, Feuer R. PMID: 27218802; PMCID: PMC4878760.
      View in: PubMed   Mentions:    Fields:    
    61. Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance. Am J Physiol Heart Circ Physiol. 2016 07 01; 311(1):H219-28. Andres AM, Kooren JA, Parker SJ, Tucker KC, Ravindran N, Ito BR, Huang C, Venkatraman V, Van Eyk JE, Gottlieb RA, Mentzer RM. PMID: 27199111; PMCID: PMC4967197.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    62. Mitochondrial remodeling: Rearranging, recycling, and reprogramming. Cell Calcium. 2016 08; 60(2):88-101. Gottlieb RA, Bernstein D. PMID: 27130902; PMCID: PMC4996709.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    63. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016; 12(2):369-80. Sin J, Andres AM, Taylor DJ, Weston T, Hiraumi Y, Stotland A, Kim BJ, Huang C, Doran KS, Gottlieb RA. PMID: 26566717; PMCID: PMC4836019.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    64. METABOLISM. Mitochondria shape cardiac metabolism. Science. 2015 Dec 04; 350(6265):1162-3. Gottlieb RA, Bernstein D. PMID: 26785456.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    65. α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J Mol Cell Cardiol. 2016 Jan; 90:53-8. Stotland A, Gottlieb RA. PMID: 26654779; PMCID: PMC4718850.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    66. Breast Cancer Survivorship and Cardiovascular Disease: Emerging Approaches in Cardio-Oncology. Curr Treat Options Cardiovasc Med. 2015 Dec; 17(12):60. Xie Y, Collins WJ, Audeh MW, Shiao SL, Gottlieb RA, Goodman MT, Merz CN, Mehta PK. PMID: 26490280; PMCID: PMC6364685.
      View in: PubMed   Mentions: 7  
    67. Lost in translation: miRNAs and mRNAs in ischemic preconditioning and ischemia/reperfusion injury. J Mol Cell Cardiol. 2016 06; 95:70-7. Gottlieb RA, Pourpirali S. PMID: 26582464; PMCID: PMC4865448.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    68. Recent progress in understanding coxsackievirus replication, dissemination, and pathogenesis. Virology. 2015 Oct; 484:288-304. Sin J, Mangale V, Thienphrapa W, Gottlieb RA, Feuer R. PMID: 26142496; PMCID: PMC4567421.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    69. Correction: The Association of Statin Use after Cancer Diagnosis with Survival in Pancreatic Cancer Patients: A SEER-Medicare Analysis. PLoS One. 2015; 10(5):e0128730. Jeon CY, Pandol SJ, Wu B, Cook-Wiens G, Gottlieb RA, Bairey Merz CN, Goodman MT. PMID: 26017388; PMCID: PMC4446309.
      View in: PubMed   Mentions: 1     Fields:    
    70. The association of statin use after cancer diagnosis with survival in pancreatic cancer patients: a SEER-medicare analysis. PLoS One. 2015; 10(4):e0121783. Jeon CY, Pandol SJ, Wu B, Cook-Wiens G, Gottlieb RA, Merz CN, Merz NB, Goodman MT. PMID: 25830309; PMCID: PMC4382214.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    71. Myocardial autophagic energy stress responses--macroautophagy, mitophagy, and glycophagy. Am J Physiol Heart Circ Physiol. 2015 May 15; 308(10):H1194-204. Delbridge LM, Mellor KM, Taylor DJ, Gottlieb RA. PMID: 25747748; PMCID: PMC4436984.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    72. Untangling autophagy measurements: all fluxed up. Circ Res. 2015 Jan 30; 116(3):504-14. Gottlieb RA, Andres AM, Sin J, Taylor DP. PMID: 25634973; PMCID: PMC4313387.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    73. Mitochondrial quality control: Easy come, easy go. Biochim Biophys Acta. 2015 Oct; 1853(10 Pt B):2802-11. Stotland A, Gottlieb RA. PMID: 25596427; PMCID: PMC4501896.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    74. Measuring cardiac autophagic flux in vitro and in vivo. Methods Mol Biol. 2015; 1219:187-97. Gurney MA, Huang C, Ramil JM, Ravindran N, Andres AM, Sin J, Linton PJ, Gottlieb RA. PMID: 25308270.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    75. This old heart: Cardiac aging and autophagy. J Mol Cell Cardiol. 2015 Jun; 83:44-54. Linton PJ, Gurney M, Sengstock D, Mentzer RM, Gottlieb RA. PMID: 25543002; PMCID: PMC4459942.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    76. MitoTimer: a novel protein for monitoring mitochondrial turnover in the heart. J Mol Med (Berl). 2015 Mar; 93(3):271-8. Gottlieb RA, Stotland A. PMID: 25479961; PMCID: PMC4333239.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    77. A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiology. J Mol Cell Cardiol. 2015 Jan; 78:62-72. Andres AM, Stotland A, Queliconi BB, Gottlieb RA. PMID: 25444712; PMCID: PMC4268279.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    78. The impact of juvenile coxsackievirus infection on cardiac progenitor cells and postnatal heart development. PLoS Pathog. 2014 Jul; 10(7):e1004249. Sin J, Puccini JM, Huang C, Konstandin MH, Gilbert PE, Sussman MA, Gottlieb RA, Feuer R. PMID: 25079373; PMCID: PMC4117602.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    79. Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers. PLoS Pathog. 2014 Apr; 10(4):e1004045. Robinson SM, Tsueng G, Sin J, Mangale V, Rahawi S, McIntyre LL, Williams W, Kha N, Cruz C, Hancock BM, Nguyen DP, Sayen MR, Hilton BJ, Doran KS, Segall AM, Wolkowicz R, Cornell CT, Whitton JL, Gottlieb RA, Feuer R. PMID: 24722773; PMCID: PMC3983045.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    80. The personal human oral microbiome obscures the effects of treatment on periodontal disease. PLoS One. 2014; 9(1):e86708. Schwarzberg K, Le R, Bharti B, Lindsay S, Casaburi G, Salvatore F, Saber MH, Alonaizan F, Slots J, Gottlieb RA, Caporaso JG, Kelley ST. PMID: 24489772; PMCID: PMC3906071.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCellsCTClinical Trials
    81. Measurement of mitochondrial turnover and life cycle using MitoTimer. Methods Enzymol. 2014; 547:21-38. Trudeau KM, Gottlieb RA, Shirihai OS. PMID: 25416350.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    82. Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. J Clin Invest. 2013 Dec; 123(12):5319-33. Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Rech M, Sheng X, Weimer BC, Gottlieb RA, White MF, Abel ED. PMID: 24177427; PMCID: PMC3859408.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    83. MitoTimer: a novel tool for monitoring mitochondrial turnover. Autophagy. 2013 Nov 01; 9(11):1852-61. Hernandez G, Thornton C, Stotland A, Lui D, Sin J, Ramil J, Magee N, Andres A, Quarato G, Carreira RS, Sayen MR, Wolkowicz R, Gottlieb RA. PMID: 24128932; PMCID: PMC4028337.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    84. MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age. Autophagy. 2013 Nov 01; 9(11):1887-96. Ferree AW, Trudeau K, Zik E, Benador IY, Twig G, Gottlieb RA, Shirihai OS. PMID: 24149000; PMCID: PMC4028338.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    85. Mitophagy is required for acute cardioprotection by simvastatin. Antioxid Redox Signal. 2014 Nov 10; 21(14):1960-73. Andres AM, Hernandez G, Lee P, Huang C, Ratliff EP, Sin J, Thornton CA, Damasco MV, Gottlieb RA. PMID: 23901824; PMCID: PMC4208607.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    86. Autophagy: an affair of the heart. Heart Fail Rev. 2013 Sep; 18(5):575-84. Gottlieb RA, Mentzer RM. PMID: 23188163; PMCID: PMC3782636.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    87. Polyamine depletion inhibits the autophagic response modulating Trypanosoma cruzi infectivity. Autophagy. 2013 Jul; 9(7):1080-93. Vanrell MC, Cueto JA, Barclay JJ, Carrillo C, Colombo MI, Gottlieb RA, Romano PS. PMID: 23697944; PMCID: PMC3722317.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    88. Activation of the homeostatic intracellular repair response during cardiac surgery. J Am Coll Surg. 2013 Apr; 216(4):719-26; discussion 726-9. Jahania SM, Sengstock D, Vaitkevicius P, Andres A, Ito BR, Gottlieb RA, Mentzer RM. PMID: 23415552; PMCID: PMC3724756.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    89. Autophagy, myocardial protection, and the metabolic syndrome. J Cardiovasc Pharmacol. 2012 Aug; 60(2):125-32. Giricz Z, Mentzer RM, Gottlieb RA. PMID: 22472909; PMCID: PMC3419804.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    90. Indigestible mitochondria cause heartburn. Cell Res. 2012 Nov; 22(11):1518-20. Gottlieb RA, Linton PJ. PMID: 22710797; PMCID: PMC3494386.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    91. Impaired mitophagy at the heart of injury. Autophagy. 2011 Dec; 7(12):1573-4. Gottlieb RA, Mentzer RM, Linton PJ. PMID: 22082870; PMCID: PMC3288037.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    92. Cell death pathways in acute ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther. 2011 Sep-Dec; 16(3-4):233-8. Gottlieb RA. PMID: 21821521; PMCID: PMC3337030.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    93. Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. PLoS One. 2011; 6(6):e20975. Huang C, Andres AM, Ratliff EP, Hernandez G, Lee P, Gottlieb RA. PMID: 21687634; PMCID: PMC3110820.
      View in: PubMed   Mentions: 184     Fields:    Translation:AnimalsCells
    94. Cardioprotection through autophagy: ready for clinical trial? Autophagy. 2011 Apr; 7(4):434-5. Gottlieb RA, Mentzer RM. PMID: 21187717; PMCID: PMC3127222.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    95. Acute induction of autophagy as a novel strategy for cardioprotection: getting to the heart of the matter. Autophagy. 2011 Apr; 7(4):432-3. Przyklenk K, Undyala VV, Wider J, Sala-Mercado JA, Gottlieb RA, Mentzer RM. PMID: 21187719; PMCID: PMC3679089.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    96. Xenotransplantation of mitochondrial electron transfer enzyme, Ndi1, in myocardial reperfusion injury. PLoS One. 2011 Feb 14; 6(2):e16288. Perry CN, Huang C, Liu W, Magee N, Carreira RS, Gottlieb RA. PMID: 21339825; PMCID: PMC3038860.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    97. Mitochondrial turnover in the heart. Biochim Biophys Acta. 2011 Jul; 1813(7):1295-301. Gottlieb RA, Gustafsson AB. PMID: 21147177; PMCID: PMC3335292.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    98. Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury. Circulation. 2010 Sep 14; 122(11 Suppl):S179-84. Sala-Mercado JA, Wider J, Undyala VV, Jahania S, Yoo W, Mentzer RM, Gottlieb RA, Przyklenk K. PMID: 20837911; PMCID: PMC3355994.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimals
    99. Autophagy: definition, molecular machinery, and potential role in myocardial ischemia-reperfusion injury. J Cardiovasc Pharmacol Ther. 2010 Sep; 15(3):220-30. Dong Y, Undyala VV, Gottlieb RA, Mentzer RM, Przyklenk K. PMID: 20595626.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    100. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy. 2010 May; 6(4):462-72. Carreira RS, Lee Y, Ghochani M, Gustafsson ÅB, Gottlieb RA. PMID: 20364102; PMCID: PMC3768271.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    101. Autophagy induced by ischemic preconditioning is essential for cardioprotection. J Cardiovasc Transl Res. 2010 Aug; 3(4):365-73. Huang C, Yitzhaki S, Perry CN, Liu W, Giricz Z, Mentzer RM, Gottlieb RA. PMID: 20559777; PMCID: PMC2899015.
      View in: PubMed   Mentions: 81     Fields:    Translation:Animals
    102. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ Res. 2010 Apr 16; 106(7):1265-74. Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, Gustafsson AB, Miyamoto S, Glembotski CC, Gottlieb RA, Brown JH, Sussman MA. PMID: 20203306; PMCID: PMC2864233.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    103. Autophagy during cardiac stress: joys and frustrations of autophagy. Annu Rev Physiol. 2010; 72:45-59. Gottlieb RA, Mentzer RM. PMID: 20148666; PMCID: PMC3682821.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    104. Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism. J Mol Cell Cardiol. 2010 Jun; 48(6):1146-56. Quinsay MN, Lee Y, Rikka S, Sayen MR, Molkentin JD, Gottlieb RA, Gustafsson AB. PMID: 20025887; PMCID: PMC2866782.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    105. Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H570-9. Huang C, Liu W, Perry CN, Yitzhaki S, Lee Y, Yuan H, Tsukada YT, Hamacher-Brady A, Mentzer RM, Gottlieb RA. PMID: 20008275; PMCID: PMC2822573.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    106. Kinetics of the translocation and phosphorylation of alphaB-crystallin in mouse heart mitochondria during ex vivo ischemia. Am J Physiol Heart Circ Physiol. 2009 May; 296(5):H1633-42. Whittaker R, Glassy MS, Gude N, Sussman MA, Gottlieb RA, Glembotski CC. PMID: 19252088; PMCID: PMC2685329.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    107. Cardioprotection requires taking out the trash. Basic Res Cardiol. 2009 Mar; 104(2):169-80. Gottlieb RA, Finley KD, Mentzer RM. PMID: 19242643; PMCID: PMC3661679.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    108. Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA. Basic Res Cardiol. 2009 Mar; 104(2):157-67. Yitzhaki S, Huang C, Liu W, Lee Y, Gustafsson AB, Mentzer RM, Gottlieb RA. PMID: 19242639; PMCID: PMC3682823.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    109. Autophagy in ischemic heart disease. Circ Res. 2009 Jan 30; 104(2):150-8. Gustafsson AB, Gottlieb RA. PMID: 19179668; PMCID: PMC2765251.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    110. Novel methods for measuring cardiac autophagy in vivo. Methods Enzymol. 2009; 453:325-42. Perry CN, Kyoi S, Hariharan N, Takagi H, Sadoshima J, Gottlieb RA. PMID: 19216914; PMCID: PMC3658837.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    111. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol. 2009 Feb; 296(2):H470-9. Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC, Gottlieb RA. PMID: 19098111; PMCID: PMC2643899.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    112. Recycle or die: the role of autophagy in cardioprotection. J Mol Cell Cardiol. 2008 Apr; 44(4):654-61. Gustafsson AB, Gottlieb RA. PMID: 18353358; PMCID: PMC2423346.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimals
    113. Eat your heart out: Role of autophagy in myocardial ischemia/reperfusion. Autophagy. 2008 May; 4(4):416-21. Gustafsson AB, Gottlieb RA. PMID: 18253087; PMCID: PMC3723414.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    114. A method to measure cardiac autophagic flux in vivo. Autophagy. 2008 Apr; 4(3):322-9. Iwai-Kanai E, Yuan H, Huang C, Sayen MR, Perry-Garza CN, Kim L, Gottlieb RA. PMID: 18216495; PMCID: PMC3709927.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    115. Chemotherapy and cardiotoxicity. Rev Cardiovasc Med. 2008; 9(2):75-83. Broder H, Gottlieb RA, Lepor NE. PMID: 18660728; PMCID: PMC3723407.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    116. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008 Feb; 4(2):151-75. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clavé C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, López-Otín C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Meléndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Münz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nürnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tallóczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcátegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL. PMID: 18188003; PMCID: PMC2654259.
      View in: PubMed   Mentions: 1199     Fields:    Translation:HumansAnimalsCells
    117. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H337-44. Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC. PMID: 17993600.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    118. The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores. FEBS J. 2007 Jun; 274(12):3184-97. Brady NR, Hamacher-Brady A, Yuan H, Gottlieb RA. PMID: 17540004.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    119. The viability of professional wet cleaning as a pollution prevention alternative to perchloroethylene dry cleaning. J Air Waste Manag Assoc. 2007 Feb; 57(2):172-8. Sinsheimer P, Grout C, Namkoong A, Gottlieb R. PMID: 17355078.
      View in: PubMed   Mentions: 3     Fields:    Translation:PHPublic Health
    120. Identification of targets of phosphorylation in heart mitochondria. Methods Mol Biol. 2007; 357:127-37. Gottlieb RA. PMID: 17172684.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    121. The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy. Cardiovasc Drugs Ther. 2006 Dec; 20(6):445-62. Hamacher-Brady A, Brady NR, Gottlieb RA. PMID: 17149555.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    122. Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart. Autophagy. 2006 Oct-Dec; 2(4):307-9. Hamacher-Brady A, Brady NR, Gottlieb RA, Gustafsson AB. PMID: 16874059.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    123. Bcl-2 family members and apoptosis, taken to heart. Am J Physiol Cell Physiol. 2007 Jan; 292(1):C45-51. Gustafsson AB, Gottlieb RA. PMID: 16943242.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    124. Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem. 2006 Oct 06; 281(40):29776-87. Hamacher-Brady A, Brady NR, Gottlieb RA. PMID: 16882669.
      View in: PubMed   Mentions: 288     Fields:    Translation:AnimalsCells
    125. Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2462-72. Wall JA, Wei J, Ly M, Belmont P, Martindale JJ, Tran D, Sun J, Chen WJ, Yu W, Oeller P, Briggs S, Gustafsson AB, Sayen MR, Gottlieb RA, Glembotski CC. PMID: 16766635.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    126. Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ. 2007 Jan; 14(1):146-57. Hamacher-Brady A, Brady NR, Logue SE, Sayen MR, Jinno M, Kirshenbaum LA, Gottlieb RA, Gustafsson AB. PMID: 16645637.
      View in: PubMed   Mentions: 314     Fields:    Translation:AnimalsCells
    127. Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors. Biochim Biophys Acta. 2006 May-Jun; 1757(5-6):667-78. Brady NR, Hamacher-Brady A, Gottlieb RA. PMID: 16730326.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    128. Clinical implications of apoptosis in ischemic myocardium. Curr Probl Cardiol. 2006 Mar; 31(3):181-264. Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J. PMID: 16503249.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    129. ICE-ing the heart. Circ Res. 2005 May 27; 96(10):1036-8. Gottlieb R. PMID: 15920026.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    130. TAT-mediated protein transduction: delivering biologically active proteins to the heart. Methods Mol Med. 2005; 112:81-90. Gustafsson AB, Gottlieb RA, Granville DJ. PMID: 16010012.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    131. Ischemia/reperfusion injury at the intersection with cell death. J Mol Cell Cardiol. 2005 Jan; 38(1):21-33. Logue SE, Gustafsson AB, Samali A, Gottlieb RA. PMID: 15623419.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    132. Functional and clinical repercussions of myocyte apoptosis in the multifaceted damage by ischemia/reperfusion injury: old and new concepts after 10 years of contributions. Cell Death Differ. 2004 Dec; 11 Suppl 2:S144-52. Scarabelli TM, Gottlieb RA. PMID: 15608693.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    133. Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. J Biol Chem. 2004 May 14; 279(20):21233-8. Gustafsson AB, Tsai JG, Logue SE, Crow MT, Gottlieb RA. PMID: 15004034.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    134. Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1321-6. Granville DJ, Tashakkor B, Takeuchi C, Gustafsson AB, Huang C, Sayen MR, Wentworth P, Yeager M, Gottlieb RA. PMID: 14734800; PMCID: PMC337051.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    135. Cytochrome P450: major player in reperfusion injury. Arch Biochem Biophys. 2003 Dec 15; 420(2):262-7. Gottlieb RA. PMID: 14654065.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    136. Mechanisms of apoptosis in the heart. J Clin Immunol. 2003 Nov; 23(6):447-59. Gustafsson AB, Gottlieb RA. PMID: 15031632.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    137. The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death. Curr Med Chem. 2003 Aug; 10(16):1527-33. Granville DJ, Gottlieb RA. PMID: 12871124.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    138. Debatable contribution of mitochondrial swelling to cell swelling in ischemia. J Mol Cell Cardiol. 2003 Jul; 35(7):735-7. Gottlieb RA. PMID: 12818563.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    139. Cytochrome c dissociation and release from mitochondria by truncated Bid and ceramide. Mitochondrion. 2003 Mar; 2(4):237-44. Yuan H, Williams SD, Adachi S, Oltersdorf T, Gottlieb RA. PMID: 16120324.
      View in: PubMed   Mentions: 14     Fields:    
    140. Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J Cell Biol. 2003 Jan 06; 160(1):65-75. Ricci JE, Gottlieb RA, Green DR. PMID: 12515825; PMCID: PMC2172744.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    141. Calpain and mitochondria in ischemia/reperfusion injury. J Biol Chem. 2002 Aug 09; 277(32):29181-6. Chen M, Won DJ, Krajewski S, Gottlieb RA. PMID: 12042324.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    142. Integrating pollution prevention technology into public policy: the case of professional wet cleaning. Environ Sci Technol. 2002 Apr 15; 36(8):1649-55. Sinsheimer P, Gottlieb R, Farrar C. PMID: 11993858.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    143. Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine. FEBS Lett. 2000 Jul 28; 478(1-2):19-25. Mutomba MC, Yuan H, Konyavko M, Adachi S, Yokoyama CB, Esser V, McGarry JD, Babior BM, Gottlieb RA. PMID: 10922462.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    144. Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia. Cell Death Differ. 1999 Oct; 6(10):987-91. He H, Li HL, Lin A, Gottlieb RA. PMID: 10556976.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    145. Enhanced DNA fragmentation in the thymus of spontaneously hypertensive rats. Am J Physiol. 1999 06; 276(6):H2135-40. Suzuki H, Delano FA, Jamshidi N, Katz D, Mori M, Kosaki K, Gottlieb RA, Ishii H, Schmid-Schönbein GW. PMID: 10362697.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    146. Effect of vacuolar proton ATPase on pHi, Ca2+, and apoptosis in neonatal cardiomyocytes during metabolic inhibition/recovery. Circ Res. 1998 Jun 15; 82(11):1139-44. Karwatowska-Prokopczuk E, Nordberg JA, Li HL, Engler RL, Gottlieb RA. PMID: 9633914.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    147. Granulocyte colony-stimulating factor upregulates the vacuolar proton ATPase in human neutrophils. Blood. 1997 Dec 01; 90(11):4598-601. Niessen H, Meisenholder GW, Li HL, Gluck SL, Lee BS, Bowman B, Engler RL, Babior BM, Gottlieb RA. PMID: 9373271.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    148. Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: possible relevance to cystic fibrosis. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3587-91. Gottlieb RA, Dosanjh A. PMID: 8622979; PMCID: PMC39654.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
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