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Harper Ronald

Title(s)Professor, Neurobiology
Phone310-825-5303
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    Collapse Research 
    Collapse Research Activities and Funding
    Autonomic and Imaging Biomarkers of SUDEP
    NIH/NINDS U01NS090407Sep 30, 2014 - Jul 31, 2020
    Role: Co-Principal Investigator
    Sleep Disordered Breathing and Passive Limb Movement in Children with Paraplegia
    NIH/NINR R21NR012810May 1, 2012 - Apr 30, 2014
    Role: Co-Principal Investigator
    Passive Foot Movement and Sleep-Disordered Breathing in Heart Failure
    NIH/NINR R21NR012292Aug 12, 2010 - Jun 30, 2013
    Role: Co-Principal Investigator
    NEURAL ACTIVITY IN CONGENITAL CENTRAL HYPOVENTILATION
    NIH/NICHD R03HD036228Apr 1, 1998 - Mar 31, 2001
    Role: Principal Investigator
    COCAINE EFFECTS ON CNS-RELATED CARDIORESPIRATORY CONTROL
    NIH/NIDA R01DA004913Sep 30, 1988 - Aug 31, 1992
    Role: Principal Investigator
    CARDIORESPIRATORY PATTERNS DURING SLEEP AND SIDS RISK
    NIH/NICHD R01HD022506Sep 1, 1987 - Jul 31, 2002
    Role: Principal Investigator
    Physiological Development in SIDS
    NIH/NICHD R01HD022695Dec 1, 1986 - Mar 31, 2012
    Role: Principal Investigator
    ANALYZE DATA IN SIDS RISK FACTORS
    NIH/NICHD N01HD032830Sep 30, 1983
    Role: Principal Investigator
    NEURAL CONTROL OF CARDIORESPIRATORY FUNCTION
    NIH/NHLBI R01HL022418Apr 1, 1978 - Feb 28, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Murugesan A, Rani MRS, Vilella L, Lacuey N, Hampson JP, Faingold CL, Friedman D, Devinsky O, Sainju RK, Schuele S, Diehl B, Nei M, Harper RM, Bateman LM, Richerson G, Lhatoo SD. Postictal serotonin levels are associated with peri-ictal apnea. Neurology. 2019 Sep 04. PMID: 31484709.
      View in: PubMed
    2. Lacuey N, Martins R, Vilella L, Hampson JP, Rani MRS, Strohl K, Zaremba A, Hampson JS, Sainju RK, Friedman D, Nei M, Scott C, Gehlbach BK, Hupp NJ, Schuele S, Ogren J, Harper RM, Allen L, Diehl B, Bateman LM, Devinsky O, Richerson GB, Lhatoo S. The association of serotonin reuptake inhibitors and benzodiazepines with ictal central apnea. Epilepsy Behav. 2019 Sep; 98(Pt A):73-79. PMID: 31301453.
      View in: PubMed
    3. Allen LA, Vos SB, Kumar R, Ogren JA, Harper RK, Winston GP, Balestrini S, Wandschneider B, Scott CA, Ourselin S, Duncan JS, Lhatoo SD, Harper RM, Diehl B. Cerebellar, limbic, and midbrain volume alterations in sudden unexpected death in epilepsy. Epilepsia. 2019 Apr; 60(4):718-729. PMID: 30868560.
      View in: PubMed
    4. Allen LA, Harper RM, Lhatoo S, Lemieux L, Diehl B. Neuroimaging of Sudden Unexpected Death in Epilepsy (SUDEP): Insights From Structural and Resting-State Functional MRI Studies. Front Neurol. 2019; 10:185. PMID: 30891003.
      View in: PubMed
    5. Vilella L, Lacuey N, Hampson JP, Rani MRS, Loparo K, Sainju RK, Friedman D, Nei M, Strohl K, Allen L, Scott C, Gehlbach BK, Zonjy B, Hupp NJ, Zaremba A, Shafiabadi N, Zhao X, Reick-Mitrisin V, Schuele S, Ogren J, Harper RM, Diehl B, Bateman LM, Devinsky O, Richerson GB, Tanner A, Tatsuoka C, Lhatoo SD. Incidence, Recurrence, and Risk Factors for Peri-ictal Central Apnea and Sudden Unexpected Death in Epilepsy. Front Neurol. 2019; 10:166. PMID: 30890997.
      View in: PubMed
    6. Lacuey N, Hampson JP, Harper RM, Miller JP, Lhatoo S. Limbic and paralimbic structures driving ictal central apnea. Neurology. 2019 Feb 12; 92(7):e655-e669. PMID: 30635481.
      View in: PubMed
    7. Vilella L, Lacuey N, Hampson JP, Rani MRS, Sainju RK, Friedman D, Nei M, Strohl K, Scott C, Gehlbach BK, Zonjy B, Hupp NJ, Zaremba A, Shafiabadi N, Zhao X, Reick-Mitrisin V, Schuele S, Ogren J, Harper RM, Diehl B, Bateman L, Devinsky O, Richerson GB, Ryvlin P, Lhatoo SD. Postconvulsive central apnea as a biomarker for sudden unexpected death in epilepsy (SUDEP). Neurology. 2019 01 15; 92(3):e171-e182. PMID: 30568003.
      View in: PubMed
    8. Macey PM, Prasad JP, Ogren JA, Moiyadi AS, Aysola RS, Kumar R, Yan-Go FL, Woo MA, Albert Thomas M, Harper RM. Sex-specific hippocampus volume changes in obstructive sleep apnea. Neuroimage Clin. 2018; 20:305-317. PMID: 30101062.
      View in: PubMed
    9. Ogren JA, Tripathi R, Macey PM, Kumar R, Stern JM, Eliashiv DS, Allen LA, Diehl B, Engel J, Rani MRS, Lhatoo SD, Harper RM. Regional cortical thickness changes accompanying generalized tonic-clonic seizures. Neuroimage Clin. 2018; 20:205-215. PMID: 30094170.
      View in: PubMed
    10. Murugesan A, Rani MRS, Hampson J, Zonjy B, Lacuey N, Faingold CL, Friedman D, Devinsky O, Sainju RK, Schuele S, Diehl B, Nei M, Harper RM, Bateman LM, Richerson G, Lhatoo SD. Serum serotonin levels in patients with epileptic seizures. Epilepsia. 2018 06; 59(6):e91-e97. PMID: 29771456.
      View in: PubMed
    11. Tom C, Roy B, Vig R, Kang DW, Aysola RS, Woo MA, Harper RM, Kumar R. Correlations between Waist and Neck Circumferences and Obstructive Sleep Apnea Characteristics. Sleep Vigil. 2018 Dec; 2(2):111-118. PMID: 30637368.
      View in: PubMed
    12. Parga JJ, Daland R, Kesavan K, Macey PM, Zeltzer L, Harper RM. A description of externally recorded womb sounds in human subjects during gestation. PLoS One. 2018; 13(5):e0197045. PMID: 29746604.
      View in: PubMed
    13. Song X, Roy B, Kang DW, Aysola RS, Macey PM, Woo MA, Yan-Go FL, Harper RM, Kumar R. Altered resting-state hippocampal and caudate functional networks in patients with obstructive sleep apnea. Brain Behav. 2018 06; 8(6):e00994. PMID: 29749715.
      View in: PubMed
    14. Macey PM, Haris N, Kumar R, Thomas MA, Woo MA, Harper RM. Obstructive sleep apnea and cortical thickness in females and males. PLoS One. 2018; 13(3):e0193854. PMID: 29509806.
      View in: PubMed
    15. Lacuey N, Zonjy B, Hampson JP, Rani MRS, Zaremba A, Sainju RK, Gehlbach BK, Schuele S, Friedman D, Devinsky O, Nei M, Harper RM, Allen L, Diehl B, Millichap JJ, Bateman L, Granner MA, Dragon DN, Richerson GB, Lhatoo SD. The incidence and significance of periictal apnea in epileptic seizures. Epilepsia. 2018 03; 59(3):573-582. PMID: 29336036.
      View in: PubMed
    16. Horne RSC, Roy B, Walter LM, Biggs SN, Tamanyan K, Weichard A, Nixon GM, Davey MJ, Ditchfield M, Harper RM, Kumar R. Regional Brain Tissue Changes and Associations with Disease Severity in Children with Sleep Disordered Breathing. Sleep. 2017 Dec 15. PMID: 29267958.
      View in: PubMed
    17. Allen LA, Harper RM, Kumar R, Guye M, Ogren JA, Lhatoo SD, Lemieux L, Scott CA, Vos SB, Rani S, Diehl B. Dysfunctional Brain Networking among Autonomic Regulatory Structures in Temporal Lobe Epilepsy Patients at High Risk of Sudden Unexpected Death in Epilepsy. Front Neurol. 2017; 8:544. PMID: 29085330.
      View in: PubMed
    18. Macey PM, Sarma MK, Prasad JP, Ogren JA, Aysola R, Harper RM, Thomas MA. Obstructive sleep apnea is associated with altered midbrain chemical concentrations. Neuroscience. 2017 Nov 05; 363:76-86. PMID: 28893651.
      View in: PubMed
    19. Parga JJ, Bhatt RR, Kesavan K, Sim MS, Karp HN, Harper RM, Zeltzer L. A prospective observational cohort study of exposure to womb-like sounds to stabilize breathing and cardiovascular patterns in preterm neonates. J Matern Fetal Neonatal Med. 2018 Sep; 31(17):2245-2251. PMID: 28587528.
      View in: PubMed
    20. Roy B, Woo MA, Wang DJJ, Fonarow GC, Harper RM, Kumar R. Reduced regional cerebral blood flow in patients with heart failure. Eur J Heart Fail. 2017 10; 19(10):1294-1302. PMID: 28560737.
      View in: PubMed
    21. Macey PM, Rieken NS, Ogren JA, Macey KE, Kumar R, Harper RM. Sex differences in insular cortex gyri responses to a brief static handgrip challenge. Biol Sex Differ. 2017; 8:13. PMID: 28435658.
      View in: PubMed
    22. Tummala S, Roy B, Vig R, Park B, Kang DW, Woo MA, Aysola R, Harper RM, Kumar R. Non-Gaussian Diffusion Imaging Shows Brain Myelin and Axonal Changes in Obstructive Sleep Apnea. J Comput Assist Tomogr. 2017 Mar/Apr; 41(2):181-189. PMID: 27801694.
      View in: PubMed
    23. Weiss SA, Orosz I, Salamon N, Moy S, Wei L, Van't Klooster MA, Knight RT, Harper RM, Bragin A, Fried I, Engel J, Staba RJ. Ripples on spikes show increased phase-amplitude coupling in mesial temporal lobe epilepsy seizure-onset zones. Epilepsia. 2016 11; 57(11):1916-1930. PMID: 27723936.
      View in: PubMed
    24. Ma MA, Kumar R, Macey PM, Yan-Go FL, Harper RM. Epiglottis cross-sectional area and oropharyngeal airway length in male and female obstructive sleep apnea patients. Nat Sci Sleep. 2016; 8:297-304. PMID: 27757056.
      View in: PubMed
    25. Harper RM. Neuroanatomical findings of significant translational importance : Comments on: Holstein, G. R., Friedrich, V. L., and Martinelli, G. P. Exp Brain Res (2016). doi:10.1007/s00221-016-4725-2. Exp Brain Res. 2016 10; 234(10):2745-6. PMID: 27586143.
      View in: PubMed
    26. Sarma MK, Macey PM, Nagarajan R, Aysola R, Harper RM, Thomas MA. Accelerated Echo Planer J-resolved Spectroscopic Imaging of Putamen and Thalamus in Obstructive Sleep Apnea. Sci Rep. 2016 09 06; 6:31747. PMID: 27596614.
      View in: PubMed
    27. Tummala S, Roy B, Park B, Kang DW, Woo MA, Harper RM, Kumar R. Associations between brain white matter integrity and disease severity in obstructive sleep apnea. J Neurosci Res. 2016 10; 94(10):915-923. PMID: 27315771.
      View in: PubMed
    28. Kesavan K, Frank P, Cordero DM, Benharash P, Harper RM. Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia. PLoS One. 2016; 11(6):e0157349. PMID: 27304988.
      View in: PubMed
    29. Shivkumar K, Ajijola OA, Anand I, Armour JA, Chen PS, Esler M, De Ferrari GM, Fishbein MC, Goldberger JJ, Harper RM, Joyner MJ, Khalsa SS, Kumar R, Lane R, Mahajan A, Po S, Schwartz PJ, Somers VK, Valderrabano M, Vaseghi M, Zipes DP. Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. J Physiol. 2016 07 15; 594(14):3911-54. PMID: 27114333.
      View in: PubMed
    30. Macey PM, Rieken NS, Kumar R, Ogren JA, Middlekauff HR, Wu P, Woo MA, Harper RM. Sex Differences in Insular Cortex Gyri Responses to the Valsalva Maneuver. Front Neurol. 2016; 7:87. PMID: 27375549.
      View in: PubMed
    31. Park B, Roy B, Woo MA, Palomares JA, Fonarow GC, Harper RM, Kumar R. Lateralized Resting-State Functional Brain Network Organization Changes in Heart Failure. PLoS One. 2016; 11(5):e0155894. PMID: 27203600.
      View in: PubMed
    32. Calton MA, Howard JR, Harper RM, Goldowitz D, Mittleman G. The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. Front Neurol. 2016; 7:78. PMID: 27242661.
      View in: PubMed
    33. Park B, Palomares JA, Woo MA, Kang DW, Macey PM, Yan-Go FL, Harper RM, Kumar R. Aberrant Insular Functional Network Integrity in Patients with Obstructive Sleep Apnea. Sleep. 2016 05 01; 39(5):989-1000. PMID: 26943471.
      View in: PubMed
    34. Macey PM, Schluter PJ, Macey KE, Harper RM. Detecting variable responses within fMRI time-series of volumes-of-interest using repeated measures ANOVA. F1000Res. 2016; 5:563. PMID: 27610219.
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    35. Macey PM, Sarma MK, Nagarajan R, Aysola R, Siegel JM, Harper RM, Thomas MA. Obstructive sleep apnea is associated with low GABA and high glutamate in the insular cortex. J Sleep Res. 2016 08; 25(4):390-4. PMID: 26843332.
      View in: PubMed
    36. Park B, Palomares JA, Woo MA, Kang DW, Macey PM, Yan-Go FL, Harper RM, Kumar R. Disrupted functional brain network organization in patients with obstructive sleep apnea. Brain Behav. 2016 03; 6(3):e00441. PMID: 27099802.
      View in: PubMed
    37. Macey PM, Ogren JA, Kumar R, Harper RM. Functional Imaging of Autonomic Regulation: Methods and Key Findings. Front Neurosci. 2015; 9:513. PMID: 26858595.
      View in: PubMed
    38. Tummala S, Palomares J, Kang DW, Park B, Woo MA, Harper RM, Kumar R. Global and Regional Brain Non-Gaussian Diffusion Changes in Newly Diagnosed Patients with Obstructive Sleep Apnea. Sleep. 2016 Jan 01; 39(1):51-7. PMID: 26285005.
      View in: PubMed
    39. Harper RM, Kumar R, Macey PM, Harper RK, Ogren JA. Impaired neural structure and function contributing to autonomic symptoms in congenital central hypoventilation syndrome. Front Neurosci. 2015; 9:415. PMID: 26578872.
      View in: PubMed
    40. Mayo MC, Deng JC, Albores J, Zeidler M, Harper RM, Avidan AY. Hypocretin Deficiency Associated with Narcolepsy Type 1 and Central Hypoventilation Syndrome in Neurosarcoidosis of the Hypothalamus. J Clin Sleep Med. 2015 Sep 15; 11(9):1063-5. PMID: 25979096.
      View in: PubMed
    41. Palomares JA, Tummala S, Wang DJ, Park B, Woo MA, Kang DW, St Lawrence KS, Harper RM, Kumar R. Water Exchange across the Blood-Brain Barrier in Obstructive Sleep Apnea: An MRI Diffusion-Weighted Pseudo-Continuous Arterial Spin Labeling Study. J Neuroimaging. 2015 Nov-Dec; 25(6):900-5. PMID: 26333175.
      View in: PubMed
    42. Wandschneider B, Koepp M, Scott C, Micallef C, Balestrini S, Sisodiya SM, Thom M, Harper RM, Sander JW, Vos SB, Duncan JS, Lhatoo S, Diehl B. Structural imaging biomarkers of sudden unexpected death in epilepsy. Brain. 2015 Oct; 138(Pt 10):2907-19. PMID: 26264515.
      View in: PubMed
    43. Baron Nelson M, Compton P, Macey PM, Patel SK, Jacob E, O'Neil S, Ogren J, Finlay JL, Harper RM. Diffusion Tensor Imaging and Neurobehavioral Outcome in Children With Brain Tumors Treated With Chemotherapy. J Pediatr Oncol Nurs. 2016 Mar-Apr; 33(2):119-28. PMID: 26219302.
      View in: PubMed
    44. Kumar R, Yadav SK, Palomares JA, Park B, Joshi SH, Ogren JA, Macey PM, Fonarow GC, Harper RM, Woo MA. Reduced regional brain cortical thickness in patients with heart failure. PLoS One. 2015; 10(5):e0126595. PMID: 25962164.
      View in: PubMed
    45. Wu P, Bandettini PA, Harper RM, Handwerker DA. Effects of thoracic pressure changes on MRI signals in the brain. J Cereb Blood Flow Metab. 2015 Jun; 35(6):1024-32. PMID: 25712496.
      View in: PubMed
    46. Woo MA, Ogren JA, Abouzeid CM, Macey PM, Sairafian KG, Saharan PS, Thompson PM, Fonarow GC, Hamilton MA, Harper RM, Kumar R. Regional hippocampal damage in heart failure. Eur J Heart Fail. 2015 May; 17(5):494-500. PMID: 25704495.
      View in: PubMed
    47. Woo MA, Palomares JA, Macey PM, Fonarow GC, Harper RM, Kumar R. Global and regional brain mean diffusivity changes in patients with heart failure. J Neurosci Res. 2015 Apr; 93(4):678-85. PMID: 25502071.
      View in: PubMed
    48. Woo MA, Yadav SK, Macey PM, Fonarow GC, Harper RM, Kumar R. Brain metabolites in autonomic regulatory insular sites in heart failure. J Neurol Sci. 2014 Nov 15; 346(1-2):271-5. PMID: 25248953.
      View in: PubMed
    49. DeGiorgio CM, Miller PR, Harper R, Gornbein J, Schrader L, Soss J, Meymandi S. Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. J Neurol Neurosurg Psychiatry. 2015 Jan; 86(1):65-70. PMID: 25201887.
      View in: PubMed
    50. Macey PM, Kumar R, Ogren JA, Woo MA, Harper RM. Global brain blood-oxygen level responses to autonomic challenges in obstructive sleep apnea. PLoS One. 2014; 9(8):e105261. PMID: 25166862.
      View in: PubMed
    51. Nelson MB, Macey PM, Harper RM, Jacob E, Patel SK, Finlay JL, Nelson MD, Compton P. Structural brain alterations in children an average of 5 years after surgery and chemotherapy for brain tumors. J Neurooncol. 2014 Sep; 119(2):317-26. PMID: 24830985.
      View in: PubMed
    52. Yadav SK, Kumar R, Macey PM, Woo MA, Yan-Go FL, Harper RM. Insular cortex metabolite changes in obstructive sleep apnea. Sleep. 2014 May 01; 37(5):951-8. PMID: 24790274.
      View in: PubMed
    53. Serber SL, Rinsky B, Kumar R, Macey PM, Fonarow GC, Harper RM. Cerebral blood flow velocity and vasomotor reactivity during autonomic challenges in heart failure. Nurs Res. 2014 May-Jun; 63(3):194-202. PMID: 24785247.
      View in: PubMed
    54. Zhong W, Tang YG, Zhao X, Go FY, Harper RM, Hui H. Treating obstructive sleep apnea with continuous positive airway pressure benefits type 2 diabetes management. Pancreas. 2014 Apr; 43(3):325-30. PMID: 24622059.
      View in: PubMed
    55. Kumar R, Pham TT, Macey PM, Woo MA, Yan-Go FL, Harper RM. Abnormal myelin and axonal integrity in recently diagnosed patients with obstructive sleep apnea. Sleep. 2014 Apr 01; 37(4):723-32. PMID: 24899761.
      View in: PubMed
    56. Kumar R, Farahvar S, Ogren JA, Macey PM, Thompson PM, Woo MA, Yan-Go FL, Harper RM. Brain putamen volume changes in newly-diagnosed patients with obstructive sleep apnea. Neuroimage Clin. 2014; 4:383-91. PMID: 24567910.
      View in: PubMed
    57. Harper RM, Kumar R, Macey PM, Woo MA, Ogren JA. Affective brain areas and sleep-disordered breathing. Prog Brain Res. 2014; 209:275-93. PMID: 24746053.
      View in: PubMed
    58. Macey PM, Kumar R, Woo MA, Yan-Go FL, Harper RM. Heart rate responses to autonomic challenges in obstructive sleep apnea. PLoS One. 2013; 8(10):e76631. PMID: 24194842.
      View in: PubMed
    59. Yadav SK, Kumar R, Macey PM, Richardson HL, Wang DJ, Woo MA, Harper RM. Regional cerebral blood flow alterations in obstructive sleep apnea. Neurosci Lett. 2013 Oct 25; 555:159-64. PMID: 24076138.
      View in: PubMed
    60. Richardson HL, Macey PM, Kumar R, Valladares EM, Woo MA, Harper RM. Neural and physiological responses to a cold pressor challenge in healthy adolescents. J Neurosci Res. 2013 Dec; 91(12):1618-27. PMID: 24105663.
      View in: PubMed
    61. Harper RM, Kumar R, Ogren JA, Macey PM. Sleep-disordered breathing: effects on brain structure and function. Respir Physiol Neurobiol. 2013 Sep 15; 188(3):383-91. PMID: 23643610.
      View in: PubMed
    62. Kumar R, Harper RM. Response. J Magn Reson Imaging. 2013 Aug; 38(2):506-7. PMID: 23576461.
      View in: PubMed
    63. Kumar R, Chavez AS, Macey PM, Woo MA, Harper RM. Brain axial and radial diffusivity changes with age and gender in healthy adults. Brain Res. 2013 May 28; 1512:22-36. PMID: 23548596.
      View in: PubMed
    64. Baron Nelson M, Compton P, Patel SK, Jacob E, Harper R. Central nervous system injury and neurobiobehavioral function in children with brain tumors: a review of the literature. Cancer Nurs. 2013 Mar-Apr; 36(2):E31-47. PMID: 22781957.
      View in: PubMed
    65. Pan A, Kumar R, Macey PM, Fonarow GC, Harper RM, Woo MA. Visual assessment of brain magnetic resonance imaging detects injury to cognitive regulatory sites in patients with heart failure. J Card Fail. 2013 Feb; 19(2):94-100. PMID: 23384634.
      View in: PubMed
    66. Ogren JA, Macey PM, Kumar R, Fonarow GC, Hamilton MA, Harper RM, Woo MA. Impaired cerebellar and limbic responses to the valsalva maneuver in heart failure. Cerebellum. 2012 Dec; 11(4):931-8. PMID: 22370874.
      View in: PubMed
    67. Macey PM, Kumar R, Yan-Go FL, Woo MA, Harper RM. Sex differences in white matter alterations accompanying obstructive sleep apnea. Sleep. 2012 Dec 01; 35(12):1603-13. PMID: 23204603.
      View in: PubMed
    68. Harper RM, Kumar R, Macey PM, Ogren JA, Richardson HL. Functional neuroanatomy and sleep-disordered breathing: implications for autonomic regulation. Anat Rec (Hoboken). 2012 Sep; 295(9):1385-95. PMID: 22851218.
      View in: PubMed
    69. Kumar R, Chavez AS, Macey PM, Woo MA, Yan-Go FL, Harper RM. Altered global and regional brain mean diffusivity in patients with obstructive sleep apnea. J Neurosci Res. 2012 Oct; 90(10):2043-52. PMID: 22715089.
      View in: PubMed
    70. Macey PM, Wu P, Kumar R, Ogren JA, Richardson HL, Woo MA, Harper RM. Differential responses of the insular cortex gyri to autonomic challenges. Auton Neurosci. 2012 May 21; 168(1-2):72-81. PMID: 22342370.
      View in: PubMed
    71. Kumar R, Woo MS, Macey PM, Woo MA, Harper RM. Progressive gray matter changes in patients with congenital central hypoventilation syndrome. Pediatr Res. 2012 Jun; 71(6):701-6. PMID: 22343924.
      View in: PubMed
    72. Kumar R, Delshad S, Woo MA, Macey PM, Harper RM. Age-related regional brain T2-relaxation changes in healthy adults. J Magn Reson Imaging. 2012 Feb; 35(2):300-8. PMID: 21987489.
      View in: PubMed
    73. Macey PM, Moiyadi AS, Kumar R, Woo MA, Harper RM. Decreased cortical thickness in central hypoventilation syndrome. Cereb Cortex. 2012 Aug; 22(8):1728-37. PMID: 21965438.
      View in: PubMed
    74. Pae EK, Yoon AJ, Ahuja B, Lau GW, Nguyen DD, Kim Y, Harper RM. Perinatal intermittent hypoxia alters ?-aminobutyric acid: a receptor levels in rat cerebellum. Int J Dev Neurosci. 2011 Dec; 29(8):819-26. PMID: 21964325.
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    75. Kumar R, Nguyen HD, Macey PM, Woo MA, Harper RM. Regional brain axial and radial diffusivity changes during development. J Neurosci Res. 2012 Feb; 90(2):346-55. PMID: 21938736.
      View in: PubMed
    76. Scorza FA, Terra VC, Arida RM, Sakamoto AC, Harper RM. Sudden death in a child with epilepsy: potential cerebellar mechanisms? Arq Neuropsiquiatr. 2011 Aug; 69(4):707-10. PMID: 21877045.
      View in: PubMed
    77. Kumar R, Woo MA, Macey PM, Fonarow GC, Hamilton MA, Harper RM. Brain axonal and myelin evaluation in heart failure. J Neurol Sci. 2011 Aug 15; 307(1-2):106-13. PMID: 21612797.
      View in: PubMed
    78. Kumar R, Nguyen HD, Ogren JA, Macey PM, Thompson PM, Fonarow GC, Hamilton MA, Harper RM, Woo MA. Global and regional putamen volume loss in patients with heart failure. Eur J Heart Fail. 2011 Jun; 13(6):651-5. PMID: 21393297.
      View in: PubMed
    79. Kumar R, Delshad S, Macey PM, Woo MA, Harper RM. Development of T2-relaxation values in regional brain sites during adolescence. Magn Reson Imaging. 2011 Feb; 29(2):185-93. PMID: 20933351.
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    80. Kumar R, Macey PM, Woo MA, Harper RM. Rostral brain axonal injury in congenital central hypoventilation syndrome. J Neurosci Res. 2010 Aug 01; 88(10):2146-54. PMID: 20209631.
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    81. DeGiorgio CM, Miller P, Meymandi S, Chin A, Epps J, Gordon S, Gornbein J, Harper RM. RMSSD, a measure of vagus-mediated heart rate variability, is associated with risk factors for SUDEP: the SUDEP-7 Inventory. Epilepsy Behav. 2010 Sep; 19(1):78-81. PMID: 20667792.
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    82. Patwari PP, Carroll MS, Rand CM, Kumar R, Harper R, Weese-Mayer DE. Congenital central hypoventilation syndrome and the PHOX2B gene: a model of respiratory and autonomic dysregulation. Respir Physiol Neurobiol. 2010 Oct 31; 173(3):322-35. PMID: 20601214.
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    83. Menteer J, Macey PM, Woo MA, Panigrahy A, Harper RM. Central nervous system changes in pediatric heart failure: a volumetric study. Pediatr Cardiol. 2010 Oct; 31(7):969-76. PMID: 20521036.
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    84. Macey PM, Kumar R, Ogren JA, Woo MA, Harper RM. Images in sleep medicine. Altered cerebral blood flow in a patient with congenital central hypoventilation syndrome. Sleep Med. 2010 Jun; 11(6):589-90. PMID: 20466586.
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    85. Macey PM, Woo MA, Kumar R, Cross RL, Harper RM. Relationship between obstructive sleep apnea severity and sleep, depression and anxiety symptoms in newly-diagnosed patients. PLoS One. 2010 Apr 16; 5(4):e10211. PMID: 20419135.
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    86. Harper RM, Kinney HC. Potential Mechanisms of Failure in the Sudden Infant Death Syndrome. Curr Pediatr Rev. 2010 Feb 01; 6(1):39-47. PMID: 22792083.
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    87. Kumar R, Nguyen HD, Macey PM, Woo MA, Harper RM. Dilated basilar arteries in patients with congenital central hypoventilation syndrome. Neurosci Lett. 2009 Dec 25; 467(2):139-43. PMID: 19822189.
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    88. Kumar R, Lee K, Macey PM, Woo MA, Harper RM. Mammillary body and fornix injury in congenital central hypoventilation syndrome. Pediatr Res. 2009 Oct; 66(4):429-34. PMID: 19581831.
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    89. Macey PM, Richard CA, Kumar R, Woo MA, Ogren JA, Avedissian C, Thompson PM, Harper RM. Hippocampal volume reduction in congenital central hypoventilation syndrome. PLoS One. 2009 Jul 30; 4(7):e6436. PMID: 19649271.
      View in: PubMed
    90. Kumar R, Macey PM, Cross RL, Woo MA, Yan-Go FL, Harper RM. Neural alterations associated with anxiety symptoms in obstructive sleep apnea syndrome. Depress Anxiety. 2009; 26(5):480-91. PMID: 18828142.
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    91. Woo MA, Kumar R, Macey PM, Fonarow GC, Harper RM. Brain injury in autonomic, emotional, and cognitive regulatory areas in patients with heart failure. J Card Fail. 2009 Apr; 15(3):214-23. PMID: 19327623.
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    92. Kumar R, Woo MA, Birrer BV, Macey PM, Fonarow GC, Hamilton MA, Harper RM. Mammillary bodies and fornix fibers are injured in heart failure. Neurobiol Dis. 2009 Feb; 33(2):236-42. PMID: 19022386.
      View in: PubMed
    93. Kumar R, Macey PM, Woo MA, Alger JR, Harper RM. Diffusion tensor imaging demonstrates brainstem and cerebellar abnormalities in congenital central hypoventilation syndrome. Pediatr Res. 2008 Sep; 64(3):275-80. PMID: 18458651.
      View in: PubMed
    94. Cross RL, Kumar R, Macey PM, Doering LV, Alger JR, Yan-Go FL, Harper RM. Neural alterations and depressive symptoms in obstructive sleep apnea patients. Sleep. 2008 Aug; 31(8):1103-9. PMID: 18714782.
      View in: PubMed
    95. Macey PM, Kumar R, Woo MA, Valladares EM, Yan-Go FL, Harper RM. Brain structural changes in obstructive sleep apnea. Sleep. 2008 Jul; 31(7):967-77. PMID: 18652092.
      View in: PubMed
    96. Kumar R, Birrer BV, Macey PM, Woo MA, Gupta RK, Yan-Go FL, Harper RM. Reduced mammillary body volume in patients with obstructive sleep apnea. Neurosci Lett. 2008 Jun 27; 438(3):330-4. PMID: 18486338.
      View in: PubMed
    97. Serber SL, Kumar R, Woo MA, Macey PM, Fonarow GC, Harper RM. Cognitive test performance and brain pathology. Nurs Res. 2008 Mar-Apr; 57(2):75-83. PMID: 18347478.
      View in: PubMed
    98. Macey PM, Woo MA, Harper RM. Hyperoxic brain effects are normalized by addition of CO2. PLoS Med. 2007 May; 4(5):e173. PMID: 17518514.
      View in: PubMed
    99. Woo MA, Macey PM, Keens PT, Kumar R, Fonarow GC, Hamilton MA, Harper RM. Aberrant central nervous system responses to the Valsalva maneuver in heart failure. Congest Heart Fail. 2007 Jan-Feb; 13(1):29-35. PMID: 17272960.
      View in: PubMed
    100. Kumar R, Macey PM, Woo MA, Alger JR, Harper RM. Elevated mean diffusivity in widespread brain regions in congenital central hypoventilation syndrome. J Magn Reson Imaging. 2006 Dec; 24(6):1252-8. PMID: 17075838.
      View in: PubMed
    101. Krakow B, Melendrez D, Warner TD, Clark JO, Sisley BN, Dorin R, Harper RM, Leahigh LK, Lee SA, Sklar D, Hollifield M. Signs and symptoms of sleep-disordered breathing in trauma survivors: a matched comparison with classic sleep apnea patients. J Nerv Ment Dis. 2006 Jun; 194(6):433-9. PMID: 16772861.
      View in: PubMed
    102. Henderson LA, Macey KE, Macey PM, Woo MA, Yan-Go FL, Harper RM. Regional brain response patterns to Cheyne-Stokes breathing. Respir Physiol Neurobiol. 2006 Jan 25; 150(1):87-93. PMID: 16337439.
      View in: PubMed
    103. Woo MA, Macey PM, Keens PT, Kumar R, Fonarow GC, Hamilton MA, Harper RM. Functional abnormalities in brain areas that mediate autonomic nervous system control in advanced heart failure. J Card Fail. 2005 Aug; 11(6):437-46. PMID: 16105635.
      View in: PubMed
    104. Kumar R, Macey PM, Woo MA, Alger JR, Keens TG, Harper RM. Neuroanatomic deficits in congenital central hypoventilation syndrome. J Comp Neurol. 2005 Jul 11; 487(4):361-71. PMID: 15906312.
      View in: PubMed
    105. Macey KE, Macey PM, Woo MA, Henderson LA, Frysinger RC, Harper RK, Alger JR, Yan-Go F, Harper RM. Inspiratory loading elicits aberrant fMRI signal changes in obstructive sleep apnea. Respir Physiol Neurobiol. 2006 Mar 28; 151(1):44-60. PMID: 15993658.
      View in: PubMed
    106. Woo MA, Macey PM, Macey KE, Keens TG, Woo MS, Harper RK, Harper RM. FMRI responses to hyperoxia in congenital central hypoventilation syndrome. Pediatr Res. 2005 Apr; 57(4):510-8. PMID: 15718370.
      View in: PubMed
    107. Macey PM, Macey KE, Woo MA, Keens TG, Harper RM. Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome. Pediatr Res. 2005 Apr; 57(4):500-9. PMID: 15718375.
      View in: PubMed
    108. Pae EK, Chien P, Harper RM. Intermittent hypoxia damages cerebellar cortex and deep nuclei. Neurosci Lett. 2005 Feb 28; 375(2):123-8. PMID: 15670654.
      View in: PubMed
    109. Pae EK, Wu J, Nguyen D, Monti R, Harper RM. Geniohyoid muscle properties and myosin heavy chain composition are altered after short-term intermittent hypoxic exposure. J Appl Physiol (1985). 2005 Mar; 98(3):889-94. PMID: 15557011.
      View in: PubMed
    110. Harper RM, Macey PM, Woo MA, Macey KE, Keens TG, Gozal D, Alger JR. Hypercapnic exposure in congenital central hypoventilation syndrome reveals CNS respiratory control mechanisms. J Neurophysiol. 2005 Mar; 93(3):1647-58. PMID: 15525806.
      View in: PubMed
    111. Henderson LA, Macey PM, Richard CA, Runquist ML, Harper RM. Functional magnetic resonance imaging during hypotension in the developing animal. J Appl Physiol (1985). 2004 Dec; 97(6):2248-57. PMID: 15220298.
      View in: PubMed
    112. Macey PM, Macey KE, Kumar R, Harper RM. A method for removal of global effects from fMRI time series. Neuroimage. 2004 May; 22(1):360-6. PMID: 15110027.
      View in: PubMed
    113. Macey PM, Valderama C, Kim AH, Woo MA, Gozal D, Keens TG, Harper RK, Harper RM. Temporal trends of cardiac and respiratory responses to ventilatory challenges in congenital central hypoventilation syndrome. Pediatr Res. 2004 Jun; 55(6):953-9. PMID: 15028846.
      View in: PubMed
    114. Kristensen MP, Rector DM, Poe GR, Harper RM. Activity changes of the cat paraventricular hypothalamus during stressor exposure. Neuroreport. 2004 Jan 19; 15(1):43-8. PMID: 15106829.
      View in: PubMed
    115. Macey PM, Alger JR, Kumar R, Macey KE, Woo MA, Harper RM. Global BOLD MRI changes to ventilatory challenges in congenital central hypoventilation syndrome. Respir Physiol Neurobiol. 2003 Dec 16; 139(1):41-50. PMID: 14637309.
      View in: PubMed
    116. Harper RM. Impaired arousals and sudden infant death syndrome: preexisting neural injury? Am J Respir Crit Care Med. 2003 Dec 01; 168(11):1262-3. PMID: 14644917.
      View in: PubMed
    117. Henderson LA, Richard CA, Macey PM, Runquist ML, Yu PL, Galons JP, Harper RM. Functional magnetic resonance signal changes in neural structures to baroreceptor reflex activation. J Appl Physiol (1985). 2004 Feb; 96(2):693-703. PMID: 14565965.
      View in: PubMed
    118. Richard CA, Rector DM, Macey PM, Ali N, Harper RM. Late-developing rostral ventrolateral medullary surface responses to cardiovascular challenges during sleep. Brain Res. 2003 Sep 19; 985(1):65-77. PMID: 12957369.
      View in: PubMed
    119. Woo MA, Macey PM, Fonarow GC, Hamilton MA, Harper RM. Regional brain gray matter loss in heart failure. J Appl Physiol (1985). 2003 Aug; 95(2):677-84. PMID: 12716866.
      View in: PubMed
    120. Poe GR, Rector DM, Harper RM. State-dependent columnar organization of dorsal hippocampal activity in the freely-behaving cat. Behav Brain Res. 2003 Jan 06; 138(1):107-12. PMID: 12493634.
      View in: PubMed
    121. Harper RM, Macey PM, Henderson LA, Woo MA, Macey KE, Frysinger RC, Alger JR, Nguyen KP, Yan-Go FL. fMRI responses to cold pressor challenges in control and obstructive sleep apnea subjects. J Appl Physiol (1985). 2003 Apr; 94(4):1583-95. PMID: 12514164.
      View in: PubMed
    122. Henderson LA, Macey PM, Macey KE, Frysinger RC, Woo MA, Harper RK, Alger JR, Yan-Go FL, Harper RM. Brain responses associated with the Valsalva maneuver revealed by functional magnetic resonance imaging. J Neurophysiol. 2002 Dec; 88(6):3477-86. PMID: 12466462.
      View in: PubMed
    123. Krakow B, Melendrez D, Warner TD, Dorin R, Harper R, Hollifield M. To breathe, perchance to sleep: sleep-disordered breathing and chronic insomnia among trauma survivors. Sleep Breath. 2002 Dec; 6(4):189-202. PMID: 12524572.
      View in: PubMed
    124. Harper RM, Richard CA, Henderson LA, Macey PM, Macey KE. Structural mechanisms underlying autonomic reactions in pediatric arousal. Sleep Med. 2002 Dec; 3 Suppl 2:S53-6. PMID: 14592381.
      View in: PubMed
    125. Macey PM, Henderson LA, Macey KE, Alger JR, Frysinger RC, Woo MA, Harper RK, Yan-Go FL, Harper RM. Brain morphology associated with obstructive sleep apnea. Am J Respir Crit Care Med. 2002 Nov 15; 166(10):1382-7. PMID: 12421746.
      View in: PubMed
    126. Henderson LA, Woo MA, Macey PM, Macey KE, Frysinger RC, Alger JR, Yan-Go F, Harper RM. Neural responses during Valsalva maneuvers in obstructive sleep apnea syndrome. J Appl Physiol (1985). 2003 Mar; 94(3):1063-74. PMID: 12433858.
      View in: PubMed
    127. Henderson LA, Yu PL, Frysinger RC, Galons JP, Bandler R, Harper RM. Neural responses to intravenous serotonin revealed by functional magnetic resonance imaging. J Appl Physiol (1985). 2002 Jan; 92(1):331-42. PMID: 11744676.
      View in: PubMed
    128. Harper RM, Woo MA, Alger JR. Visualization of sleep influences on cerebellar and brainstem cardiac and respiratory control mechanisms. Brain Res Bull. 2000 Sep 01; 53(1):125-31. PMID: 11033217.
      View in: PubMed
    129. Harper RM, Bandler R, Spriggs D, Alger JR. Lateralized and widespread brain activation during transient blood pressure elevation revealed by magnetic resonance imaging. J Comp Neurol. 2000 Feb 07; 417(2):195-204. PMID: 10660897.
      View in: PubMed
    130. Harper RM, Kinney HC, Fleming PJ, Thach BT. Sleep influences on homeostatic functions: implications for sudden infant death syndrome. Respir Physiol. 2000 Feb; 119(2-3):123-32. PMID: 10722855.
      View in: PubMed
    131. Harper RM, Gozal D, Bandler R, Spriggs D, Lee J, Alger J. Regional brain activation in humans during respiratory and blood pressure challenges. Clin Exp Pharmacol Physiol. 1998 Jun; 25(6):483-6. PMID: 9673830.
      View in: PubMed