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Szymusiak, Ronald

Title(s)Adjunct Professor, Medicine
Phone818-891-7711
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    Collapse Research 
    Collapse Research Activities and Funding
    BLR&D Research Career Scientist Award
    VA IK6BX004208Apr 1, 2018 - Mar 31, 2025
    Role: Principal Investigator
    GABAergic Switches Control Wakefulness, NREM sleep and REM sleep
    NIH/NINDS R01NS092383Apr 15, 2016 - Mar 31, 2021
    Role: Co-Principal Investigator
    Resolution of the Mechanisms Responsible for Atonia during REM Sleep
    NIH/NINDS R01NS094062Sep 15, 2015 - Aug 31, 2020
    Role: Co-Principal Investigator
    Impact of Corticotropin Releasing Factor on Sleep Regulation
    VA I01BX001556Oct 1, 2011 - Sep 30, 2020
    Role: Principal Investigator
    Median Preoptic Nucleus and the Control of Sleep
    NIH/NIMH R01MH063323Jul 1, 2001 - May 31, 2007
    Role: Principal Investigator
    SLEEP AND EEG MECHANISMS: THE BASAL FOREBRAIN
    NIH/NINDS R01NS022127Jan 1, 1987 - Dec 31, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Leisman DE, Harhay MO, Lederer DJ, Abramson M, Adjei AA, Bakker J, Ballas ZK, Barreiro E, Bell SC, Bellomo R, Bernstein JA, Branson RD, Brusasco V, Chalmers JD, Chokroverty S, Citerio G, Collop NA, Cooke CR, Crapo JD, Donaldson G, Fitzgerald DA, Grainger E, Hale L, Herth FJ, Kochanek PM, Marks G, Moorman JR, Ost DE, Schatz M, Sheikh A, Smyth AR, Stewart I, Stewart PW, Swenson ER, Szymusiak R, Teboul JL, Vincent JL, Wedzicha JA, Maslove DM. Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Crit Care Med. 2020 Mar 04. PMID: 32141923.
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    2. Szymusiak R, Manber R. Remembering the Contributions of Christian Guilleminault to SLEEP. Sleep. 2019 12 24; 42(12). PMID: 31875231.
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    3. Kostin A, Alam MA, McGinty D, Szymusiak R, Alam MN. Chronic Suppression of Hypothalamic Cell Proliferation and Neurogenesis Induces Aging-Like Changes in Sleep-Wake Organization in Young Mice. Neuroscience. 2019 04 15; 404:541-556. PMID: 30738854.
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    4. Lederer DJ, Bell SC, Branson RD, Chalmers JD, Marshall R, Maslove DM, Ost DE, Punjabi NM, Schatz M, Smyth AR, Stewart PW, Suissa S, Adjei AA, Akdis CA, Azoulay É, Bakker J, Ballas ZK, Bardin PG, Barreiro E, Bellomo R, Bernstein JA, Brusasco V, Buchman TG, Chokroverty S, Collop NA, Crapo JD, Fitzgerald DA, Hale L, Hart N, Herth FJ, Iwashyna TJ, Jenkins G, Kolb M, Marks GB, Mazzone P, Moorman JR, Murphy TM, Noah TL, Reynolds P, Riemann D, Russell RE, Sheikh A, Sotgiu G, Swenson ER, Szczesniak R, Szymusiak R, Teboul JL, Vincent JL. Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals. Ann Am Thorac Soc. 2019 01; 16(1):22-28. PMID: 30230362.
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    5. Alam MA, Kostin A, Siegel J, McGinty D, Szymusiak R, Alam MN. Characteristics of sleep-active neurons in the medullary parafacial zone in rats. Sleep. 2018 10 01; 41(10). PMID: 29986116.
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    6. Szymusiak R. Body temperature and sleep. Handb Clin Neurol. 2018; 156:341-351. PMID: 30454599.
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    7. Donlea JM, Alam MN, Szymusiak R. Neuronal substrates of sleep homeostasis; lessons from flies, rats and mice. Curr Opin Neurobiol. 2017 06; 44:228-235. PMID: 28628804.
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    8. Szymusiak R. Changes for SLEEP in 2017. Sleep. 2017 Jan 01; 40(1). PMID: 30247695.
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    9. Gvilia I, Suntsova N, Kostin A, Kalinchuk A, McGinty D, Basheer R, Szymusiak R. The role of adenosine in the maturation of sleep homeostasis in rats. J Neurophysiol. 2017 01 01; 117(1):327-335. PMID: 27784808.
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    10. Gvilia I, Suntsova N, Kumar S, McGinty D, Szymusiak R. Suppression of preoptic sleep-regulatory neuronal activity during corticotropin-releasing factor-induced sleep disturbance. Am J Physiol Regul Integr Comp Physiol. 2015 Nov 01; 309(9):R1092-100. PMID: 26333784.
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    11. Pien GW, Szymusiak R, Ryden AM, Avidan AY, Stansbury RC, Strollo PJ, Fields BG, Rosen IM, Strohl KP. ATS Core Curriculum 2014: part III. Adult sleep medicine. Ann Am Thorac Soc. 2014 Nov; 11(9):1480-7. PMID: 25422999.
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    12. Zee PC, Badr MS, Kushida C, Mullington JM, Pack AI, Parthasarathy S, Redline S, Szymusiak RS, Walsh JK, Watson NF. Strategic opportunities in sleep and circadian research: report of the Joint Task Force of the Sleep Research Society and American Academy of Sleep Medicine. Sleep. 2014 Feb 01; 37(2):219-27. PMID: 24501434.
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    13. Alam MA, Kumar S, McGinty D, Alam MN, Szymusiak R. Neuronal activity in the preoptic hypothalamus during sleep deprivation and recovery sleep. J Neurophysiol. 2014 Jan; 111(2):287-99. PMID: 24174649.
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    14. Kostin A, McGinty D, Szymusiak R, Alam MN. Sleep-wake and diurnal modulation of nitric oxide in the perifornical-lateral hypothalamic area: real-time detection in freely behaving rats. Neuroscience. 2013 Dec 19; 254:275-84. PMID: 24056193.
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    15. Bittman EL, Kilduff TS, Kriegsfeld LJ, Szymusiak R, Toth LA, Turek FW. Animal care practices in experiments on biological rhythms and sleep: report of the Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society. J Am Assoc Lab Anim Sci. 2013 Jul; 52(4):437-43. PMID: 23849440.
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    16. Kumar S, Rai S, Hsieh KC, McGinty D, Alam MN, Szymusiak R. Adenosine A(2A) receptors regulate the activity of sleep regulatory GABAergic neurons in the preoptic hypothalamus. Am J Physiol Regul Integr Comp Physiol. 2013 Jul 01; 305(1):R31-41. PMID: 23637137.
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    17. Kostin A, McGinty D, Szymusiak R, Alam MN. Mechanisms mediating effects of nitric oxide on perifornical lateral hypothalamic neurons. Neuroscience. 2012 Sep 18; 220:179-90. PMID: 22705724.
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    18. Methippara M, Mitrani B, Schrader FX, Szymusiak R, McGinty D. Salubrinal, an endoplasmic reticulum stress blocker, modulates sleep homeostasis and activation of sleep- and wake-regulatory neurons. Neuroscience. 2012 May 03; 209:108-18. PMID: 22387272.
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    19. Hsieh KC, Gvilia I, Kumar S, Uschakov A, McGinty D, Alam MN, Szymusiak R. c-Fos expression in neurons projecting from the preoptic and lateral hypothalamic areas to the ventrolateral periaqueductal gray in relation to sleep states. Neuroscience. 2011 Aug 11; 188:55-67. PMID: 21601616.
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    20. Kumar S, Alam MN, Rai S, Bashir T, McGinty D, Szymusiak R. Central nervous system sites of the sleep promoting effects of eszopiclone in rats. Neuroscience. 2011 May 05; 181:67-78. PMID: 21382446.
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    21. Gvilia I, Suntsova N, Angara B, McGinty D, Szymusiak R. Maturation of sleep homeostasis in developing rats: a role for preoptic area neurons. Am J Physiol Regul Integr Comp Physiol. 2011 Apr; 300(4):R885-94. PMID: 21325650.
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    22. Kostin A, Rai S, Kumar S, Szymusiak R, McGinty D, Alam MN. Nitric oxide production in the perifornical-lateral hypothalamic area and its influences on the modulation of perifornical-lateral hypothalamic area neurons. Neuroscience. 2011 Apr 14; 179:159-69. PMID: 21277356.
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    23. Szymusiak R. Hypothalamic versus neocortical control of sleep. Curr Opin Pulm Med. 2010 Nov; 16(6):530-5. PMID: 20739890.
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    24. Sportiche N, Suntsova N, Methippara M, Bashir T, Mitrani B, Szymusiak R, McGinty D. Sustained sleep fragmentation results in delayed changes in hippocampal-dependent cognitive function associated with reduced dentate gyrus neurogenesis. Neuroscience. 2010 Sep 29; 170(1):247-58. PMID: 20600652.
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    25. Methippara M, Bashir T, Suntsova N, Szymusiak R, McGinty D. Hippocampal adult neurogenesis is enhanced by chronic eszopiclone treatment in rats. J Sleep Res. 2010 Sep; 19(3):384-93. PMID: 20408925.
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    26. Alam MN, Kumar S, Suntsova N, Bashir T, Szymusiak R, McGinty D. GABAergic regulation of the perifornical-lateral hypothalamic neurons during non-rapid eye movement sleep in rats. Neuroscience. 2010 May 19; 167(3):920-8. PMID: 20188152.
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    27. Rai S, Kumar S, Alam MA, Szymusiak R, McGinty D, Alam MN. A1 receptor mediated adenosinergic regulation of perifornical-lateral hypothalamic area neurons in freely behaving rats. Neuroscience. 2010 Apr 28; 167(1):40-8. PMID: 20109537.
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    28. Uschakov A, McGinty D, Szymusiak R, McKinley MJ. Functional correlates of activity in neurons projecting from the lamina terminalis to the ventrolateral periaqueductal gray. Eur J Neurosci. 2009 Dec; 30(12):2347-55. PMID: 20092577.
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    29. Peterfi Z, McGinty D, Sarai E, Szymusiak R. Growth hormone-releasing hormone activates sleep regulatory neurons of the rat preoptic hypothalamus. Am J Physiol Regul Integr Comp Physiol. 2010 Jan; 298(1):R147-56. PMID: 19889861.
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    30. Alam MN, Kumar S, Rai S, Methippara M, Szymusiak R, McGinty D. Role of adenosine A(1) receptor in the perifornical-lateral hypothalamic area in sleep-wake regulation in rats. Brain Res. 2009 Dec 22; 1304:96-104. PMID: 19781535.
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    31. Suntsova N, Kumar S, Guzman-Marin R, Alam MN, Szymusiak R, McGinty D. A role for the preoptic sleep-promoting system in absence epilepsy. Neurobiol Dis. 2009 Oct; 36(1):126-41. PMID: 19631751.
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    32. Szymusiak R. Sleepy synapses. Commentary on Hanlon et al. "Effects of skilled training on sleep slow wave activity and cortical gene expression in the rat" Sleep 2009;32:719-729. Sleep. 2009 Jun; 32(6):713-4. PMID: 19544744.
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    33. Methippara MM, Bashir T, Kumar S, Alam N, Szymusiak R, McGinty D. Salubrinal, an inhibitor of protein synthesis, promotes deep slow wave sleep. Am J Physiol Regul Integr Comp Physiol. 2009 Jan; 296(1):R178-84. PMID: 18971348.
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    34. Kumar S, Szymusiak R, Bashir T, Suntsova N, Rai S, McGinty D, Alam MN. Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat. Brain Res. 2008 Oct 09; 1234:66-77. PMID: 18722360.
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    35. Guzman-Marin R, Suntsova N, Bashir T, Nienhuis R, Szymusiak R, McGinty D. Rapid eye movement sleep deprivation contributes to reduction of neurogenesis in the hippocampal dentate gyrus of the adult rat. Sleep. 2008 Feb; 31(2):167-75. PMID: 18274263.
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    36. Szymusiak R, McGinty D. Hypothalamic regulation of sleep and arousal. Ann N Y Acad Sci. 2008; 1129:275-86. PMID: 18591488.
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    37. Methippara MM, Alam MN, Kumar S, Bashir T, Szymusiak R, McGinty D. Administration of the protein synthesis inhibitor, anisomycin, has distinct sleep-promoting effects in lateral preoptic and perifornical hypothalamic sites in rats. Neuroscience. 2008 Jan 02; 151(1):1-11. PMID: 18055127.
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    38. Uschakov A, Gong H, McGinty D, Szymusiak R. Efferent projections from the median preoptic nucleus to sleep- and arousal-regulatory nuclei in the rat brain. Neuroscience. 2007 Nov 30; 150(1):104-20. PMID: 17928156.
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    39. Guzman-Marin R, Bashir T, Suntsova N, Szymusiak R, McGinty D. Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat. Neuroscience. 2007 Aug 10; 148(1):325-33. PMID: 17630219.
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    40. Guzman-Marin R, Suntsova N, Bashir T, Szymusiak R, McGinty D. Cell proliferation in the dentate gyrus of the adult rat fluctuates with the light-dark cycle. Neurosci Lett. 2007 Jul 18; 422(3):198-201. PMID: 17611030.
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    41. Szymusiak R, Gvilia I, McGinty D. Hypothalamic control of sleep. Sleep Med. 2007 Jun; 8(4):291-301. PMID: 17468047.
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    42. Suntsova N, Guzman-Marin R, Kumar S, Alam MN, Szymusiak R, McGinty D. The median preoptic nucleus reciprocally modulates activity of arousal-related and sleep-related neurons in the perifornical lateral hypothalamus. J Neurosci. 2007 Feb 14; 27(7):1616-30. PMID: 17301170.
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    43. Kumar S, Szymusiak R, Bashir T, Rai S, McGinty D, Alam MN. Effects of serotonin on perifornical-lateral hypothalamic area neurons in rat. Eur J Neurosci. 2007 Jan; 25(1):201-12. PMID: 17241281.
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    44. Noor Alam MD, Szymusiak R, McGinty D. Adenosinergic regulation of sleep: multiple sites of action in the brain. Sleep. 2006 Nov; 29(11):1384-5; discussion 1387-9. PMID: 17162983.
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    45. Gvilia I, Xu F, McGinty D, Szymusiak R. Homeostatic regulation of sleep: a role for preoptic area neurons. J Neurosci. 2006 Sep 13; 26(37):9426-33. PMID: 16971526.
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    46. Guzman-Marin R, Ying Z, Suntsova N, Methippara M, Bashir T, Szymusiak R, Gomez-Pinilla F, McGinty D. Suppression of hippocampal plasticity-related gene expression by sleep deprivation in rats. J Physiol. 2006 Sep 15; 575(Pt 3):807-19. PMID: 16825295.
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    47. Uschakov A, Gong H, McGinty D, Szymusiak R. Sleep-active neurons in the preoptic area project to the hypothalamic paraventricular nucleus and perifornical lateral hypothalamus. Eur J Neurosci. 2006 Jun; 23(12):3284-96. PMID: 16820018.
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    48. Gvilia I, Turner A, McGinty D, Szymusiak R. Preoptic area neurons and the homeostatic regulation of rapid eye movement sleep. J Neurosci. 2006 Mar 15; 26(11):3037-44. PMID: 16540582.
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    49. Gvilia I, Angara C, McGinty D, Szymusiak R. Different neuronal populations of the rat median preoptic nucleus express c-fos during sleep and in response to hypertonic saline or angiotensin-II. J Physiol. 2005 Dec 01; 569(Pt 2):587-99. PMID: 16210350.
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    50. Guzman-Marin R, Suntsova N, Methippara M, Greiffenstein R, Szymusiak R, McGinty D. Sleep deprivation suppresses neurogenesis in the adult hippocampus of rats. Eur J Neurosci. 2005 Oct; 22(8):2111-6. PMID: 16262649.
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    51. Methippara MM, Kumar S, Alam MN, Szymusiak R, McGinty D. Effects on sleep of microdialysis of adenosine A1 and A2a receptor analogs into the lateral preoptic area of rats. Am J Physiol Regul Integr Comp Physiol. 2005 Dec; 289(6):R1715-23. PMID: 16109808.
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    52. Baker FC, Angara C, Szymusiak R, McGinty D. Persistence of sleep-temperature coupling after suprachiasmatic nuclei lesions in rats. Am J Physiol Regul Integr Comp Physiol. 2005 Sep; 289(3):R827-38. PMID: 15860650.
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    53. Alam MN, Kumar S, Bashir T, Suntsova N, Methippara MM, Szymusiak R, McGinty D. GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats. J Physiol. 2005 Mar 01; 563(Pt 2):569-82. PMID: 15613374.
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    54. Baker FC, Shah S, Stewart D, Angara C, Gong H, Szymusiak R, Opp MR, McGinty D. Interleukin 1beta enhances non-rapid eye movement sleep and increases c-Fos protein expression in the median preoptic nucleus of the hypothalamus. Am J Physiol Regul Integr Comp Physiol. 2005 Apr; 288(4):R998-R1005. PMID: 15604300.
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    55. Alam MN, McGinty D, Bashir T, Kumar S, Imeri L, Opp MR, Szymusiak R. Interleukin-1beta modulates state-dependent discharge activity of preoptic area and basal forebrain neurons: role in sleep regulation. Eur J Neurosci. 2004 Jul; 20(1):207-16. PMID: 15245493.
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    56. McGinty D, Gong H, Suntsova N, Alam MN, Methippara M, Guzman-Marin R, Szymusiak R. Sleep-promoting functions of the hypothalamic median preoptic nucleus: inhibition of arousal systems. Arch Ital Biol. 2004 Jul; 142(4):501-9. PMID: 15493551.
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    57. McGinty D, Metes A, Alam MN, Megirian D, Stewart D, Szymusiak R. Preoptic hypothalamic warming suppresses laryngeal dilator activity during sleep. Am J Physiol Regul Integr Comp Physiol. 2004 Jun; 286(6):R1129-37. PMID: 14988083.
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    58. Gong H, McGinty D, Guzman-Marin R, Chew KT, Stewart D, Szymusiak R. Activation of c-fos in GABAergic neurones in the preoptic area during sleep and in response to sleep deprivation. J Physiol. 2004 May 01; 556(Pt 3):935-46. PMID: 14966298.
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    59. McGinty D, Szymusiak R. Hypothalamic regulation of sleep and arousal. Front Biosci. 2003 Sep 01; 8:s1074-83. PMID: 12957869.
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    60. Guzmán-Marín R, Suntsova N, Stewart DR, Gong H, Szymusiak R, McGinty D. Sleep deprivation reduces proliferation of cells in the dentate gyrus of the hippocampus in rats. J Physiol. 2003 Jun 01; 549(Pt 2):563-71. PMID: 12679377.
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    61. Szymusiak R, Nitz D. Chronic recording of extracellular neuronal activity in behaving animals. Curr Protoc Neurosci. 2003 Feb; Chapter 6:Unit 6.16. PMID: 18428581.
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    62. Methippara MM, Alam MN, Szymusiak R, McGinty D. Preoptic area warming inhibits wake-active neurons in the perifornical lateral hypothalamus. Brain Res. 2003 Jan 17; 960(1-2):165-73. PMID: 12505669.
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    63. Suntsova N, Szymusiak R, Alam MN, Guzman-Marin R, McGinty D. Sleep-waking discharge patterns of median preoptic nucleus neurons in rats. J Physiol. 2002 Sep 01; 543(Pt 2):665-77. PMID: 12205198.
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    64. Alam MN, Gong H, Alam T, Jaganath R, McGinty D, Szymusiak R. Sleep-waking discharge patterns of neurons recorded in the rat perifornical lateral hypothalamic area. J Physiol. 2002 Jan 15; 538(Pt 2):619-31. PMID: 11790824.
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    65. McGinty D, Szymusiak R. Brain structures and mechanisms involved in the generation of NREM sleep: focus on the preoptic hypothalamus. Sleep Med Rev. 2001 Aug; 5(4):323-342. PMID: 12530996.
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    66. Szymusiak R, Steininger T, Alam N, McGinty D. Preoptic area sleep-regulating mechanisms. Arch Ital Biol. 2001 Feb; 139(1-2):77-92. PMID: 11256189.
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    67. McGinty D, Alam MN, Szymusiak R, Nakao M, Yamamoto M. Hypothalamic sleep-promoting mechanisms: coupling to thermoregulation. Arch Ital Biol. 2001 Feb; 139(1-2):63-75. PMID: 11256188.
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    68. Steininger TL, Gong H, McGinty D, Szymusiak R. Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups. J Comp Neurol. 2001 Jan 22; 429(4):638-53. PMID: 11135241.
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    69. Guzmán-Marín R, Alam MN, Mihailescu S, Szymusiak R, McGinty D, Drucker-Colín R. Subcutaneous administration of nicotine changes dorsal raphe serotonergic neurons discharge rate during REM sleep. Brain Res. 2001 Jan 12; 888(2):321-325. PMID: 11150492.
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    70. Gong H, Szymusiak R, King J, Steininger T, McGinty D. Sleep-related c-Fos protein expression in the preoptic hypothalamus: effects of ambient warming. Am J Physiol Regul Integr Comp Physiol. 2000 Dec; 279(6):R2079-88. PMID: 11080072.
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    71. Methippara MM, Alam MN, Szymusiak R, McGinty D. Effects of lateral preoptic area application of orexin-A on sleep-wakefulness. Neuroreport. 2000 Nov 09; 11(16):3423-6. PMID: 11095491.
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    72. Szymusiak R, Alam N, McGinty D. Discharge patterns of neurons in cholinergic regions of the basal forebrain during waking and sleep. Behav Brain Res. 2000 Nov; 115(2):171-82. PMID: 11000419.
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    73. Guzmán-Marín R, Alam MN, Szymusiak R, Drucker-Colín R, Gong H, McGinty D. Discharge modulation of rat dorsal raphe neurons during sleep and waking: effects of preoptic/basal forebrain warming. Brain Res. 2000 Sep 01; 875(1-2):23-34. PMID: 10967295.
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    74. McGinty D, Szymusiak R. The sleep-wake switch: A neuronal alarm clock. Nat Med. 2000 May; 6(5):510-1. PMID: 10802704.
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    75. Alam MN, Szymusiak R, Gong H, King J, McGinty D. Adenosinergic modulation of rat basal forebrain neurons during sleep and waking: neuronal recording with microdialysis. J Physiol. 1999 Dec 15; 521 Pt 3:679-90. PMID: 10601498.
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    76. Nakao M, McGinty D, Szymusiak R, Yamamoto M. Thermoregulatory model of sleep control: losing the heat memory. J Biol Rhythms. 1999 Dec; 14(6):547-56. PMID: 10643752.
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    77. Nakao M, Nishiyama H, McGinty D, Szymusiak R, Yamamoto M. A model-based interpretation of the biphasic daily pattern of sleepiness. Biol Cybern. 1999 Nov; 81(5-6):403-14. PMID: 10592016.
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    78. Hays TC, Szymusiak R, McGinty D. GABAA receptor modulation of temperature sensitive neurons in the diagonal band of Broca in vitro. Brain Res. 1999 Oct 23; 845(2):215-23. PMID: 10536201.
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    79. Steininger TL, Alam MN, Gong H, Szymusiak R, McGinty D. Sleep-waking discharge of neurons in the posterior lateral hypothalamus of the albino rat. Brain Res. 1999 Sep 04; 840(1-2):138-47. PMID: 10517961.
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    80. Szymusiak R, Alam N, Steininger TL, McGinty D. Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res. 1998 Aug 24; 803(1-2):178-88. PMID: 9729371.
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    81. Alam MN, McGinty D, Szymusiak R. Thermosensitive neurons of the diagonal band in rats: relation to wakefulness and non-rapid eye movement sleep. Brain Res. 1997 Mar 28; 752(1-2):81-9. PMID: 9106443.
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    82. Hays T, Morairty S, Szymusiak R, McGinty D. The effects of temperature and synaptic blockade in vitro on neurons of the horizontal limb of the diagonal band of Broca in the rat basal forebrain. Brain Res. 1997 Jan 23; 746(1-2):52-8. PMID: 9037483.
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    83. Shouse MN, Langer J, Bier M, Farber PR, Alcalde O, Moghimi R, Richkind M, Szymusiak R. The alpha 2 adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2 adrenoreceptor antagonist idazoxan promotes seizures: pontine microinfusion studies of amygdala-kindled kittens. Brain Res. 1996 Aug 26; 731(1-2):203-7. PMID: 8883871.
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    84. Shouse MN, Langer J, Bier M, Farber PR, Alcalde O, Moghimi R, Richkind M, Szymusiak R. The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects. Epilepsia. 1996 Aug; 37(8):709-17. PMID: 8764807.
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    85. Alam MN, McGinty D, Szymusiak R. Preoptic/anterior hypothalamic neurons: thermosensitivity in wakefulness and non rapid eye movement sleep. Brain Res. 1996 Apr 29; 718(1-2):76-82. PMID: 8773767.
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    86. Szymusiak R, Shouse MN, McGinty D. Brainstem stimulation during sleep evokes abnormal rhythmic activity in thalamic neurons in feline penicillin epilepsy. Brain Res. 1996 Mar 25; 713(1-2):253-60. PMID: 8724998.
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    87. Alam MN, McGinty D, Szymusiak R. Neuronal discharge of preoptic/anterior hypothalamic thermosensitive neurons: relation to NREM sleep. Am J Physiol. 1995 Nov; 269(5 Pt 2):R1240-9. PMID: 7503316.
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    88. Alam MN, McGinty D, Szymusiak R. Preoptic/anterior hypothalamic neurons: thermosensitivity in rapid eye movement sleep. Am J Physiol. 1995 Nov; 269(5 Pt 2):R1250-7. PMID: 7503317.
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    89. Alam N, Szymusiak R, McGinty D. Local preoptic/anterior hypothalamic warming alters spontaneous and evoked neuronal activity in the magno-cellular basal forebrain. Brain Res. 1995 Oct 23; 696(1-2):221-30. PMID: 8574673.
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    90. Szymusiak R. Magnocellular nuclei of the basal forebrain: substrates of sleep and arousal regulation. Sleep. 1995 Jul; 18(6):478-500. PMID: 7481420.
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    91. Shouse MN, Langer J, King A, Alcalde O, Bier M, Szymusiak R, Wada Y. Paroxysmal microarousals in amygdala-kindled kittens: could they be subclinical seizures? Epilepsia. 1995 Mar; 36(3):290-300. PMID: 7614914.
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    92. Nakao M, McGinty D, Szymusiak R, Yamamoto M. Dynamical features of thermoregulatory model of sleep control. Jpn J Physiol. 1995; 45(2):311-26. PMID: 7563966.
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    93. Nakao M, McGinty D, Szymusiak R, Yamamoto M. A thermoregulatory model of sleep control. Jpn J Physiol. 1995; 45(2):291-309. PMID: 7563965.
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    94. Krilowicz BL, Szymusiak R, McGinty D. Regulation of posterior lateral hypothalamic arousal related neuronal discharge by preoptic anterior hypothalamic warming. Brain Res. 1994 Dec 30; 668(1-2):30-8. PMID: 7704615.
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    95. McGinty D, Szymusiak R, Thomson D. Preoptic/anterior hypothalamic warming increases EEG delta frequency activity within non-rapid eye movement sleep. Brain Res. 1994 Dec 26; 667(2):273-7. PMID: 7697366.
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    96. Shouse MN, Langer JV, Alcalde OG, Szymusiak RS. Ontogeny of feline temporal lobe epilepsy. III: Spontaneous sleep and arousal disorders in amygdala-kindled kittens. Epilepsia. 1994 Nov-Dec; 35(6):1289-98. PMID: 7988523.
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    97. Shouse MN, Bier M, Langer J, Alcalde O, Richkind M, Szymusiak R. The alpha 2-agonist clonidine suppresses seizures, whereas the alpha 2-antagonist idazoxan promotes seizures--a microinfusion study in amygdala-kindled kittens. Brain Res. 1994 Jun 20; 648(2):352-6. PMID: 7922553.
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    98. Szymusiak R, Danowski J, McGinty D. REM sleep-suppressing effects of atropine in cats vary with environmental temperature. Brain Res. 1994 Feb 04; 636(1):115-8. PMID: 8156400.
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    99. Szymusiak R, McGinty D, Fairchild MD, Jenden DJ. Sleep-wake disturbances in an animal model of chronic cholinergic insufficiency. Brain Res. 1993 Nov 26; 629(1):141-5. PMID: 7904530.
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    100. Morairty SR, Szymusiak R, Thomson D, McGinty DJ. Selective increases in non-rapid eye movement sleep following whole body heating in rats. Brain Res. 1993 Jul 16; 617(1):10-6. PMID: 8374732.
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    101. Szymusiak R, Danowski J, McGinty D. Exposure to heat restores sleep in cats with preoptic/anterior hypothalamic cell loss. Brain Res. 1991 Feb 08; 541(1):134-8. PMID: 2029614.
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    102. McGinty D, Szymusiak R. Keeping cool: a hypothesis about the mechanisms and functions of slow-wave sleep. Trends Neurosci. 1990 Dec; 13(12):480-7. PMID: 1703678.
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    103. Szymusiak R, McGinty D, Shouse MN, Shepard D, Sterman MB. Effects of systemic atropine sulfate administration on the frequency content of the cat sensorimotor EEG during sleep and waking. Behav Neurosci. 1990 Feb; 104(1):217-25. PMID: 2317279.
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    104. Szymusiak R, McGinty D. Control of slow wave sleep by thermoregulatory mechanisms. Prog Clin Biol Res. 1990; 345:53-64; discussion 65-6. PMID: 2377644.
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    105. Shouse MN, Siegel JM, Wu MF, Szymusiak R, Morrison AR. Mechanisms of seizure suppression during rapid-eye-movement (REM) sleep in cats. Brain Res. 1989 Dec 29; 505(2):271-82. PMID: 2598045.
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    106. Szymusiak R, McGinty D. Effects of basal forebrain stimulation on the waking discharge of neurons in the midbrain reticular formation of cats. Brain Res. 1989 Oct 02; 498(2):355-9. PMID: 2790488.
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    107. Szymusiak R, McGinty D, Sterman MB. Sleep research. Science. 1989 Sep 15; 245(4923):1165. PMID: 2781274.
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    108. Szymusiak R, Iriye T, McGinty D. Sleep-waking discharge of neurons in the posterior lateral hypothalamic area of cats. Brain Res Bull. 1989 Jul-Aug; 23(1-2):111-20. PMID: 2804703.
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    109. Szymusiak R, McGinty D. Sleep-waking discharge of basal forebrain projection neurons in cats. Brain Res Bull. 1989 Feb; 22(2):423-30. PMID: 2706546.
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    110. McGinty D, Szymusiak R. Neuronal unit activity patterns in behaving animals: brainstem and limbic system. Annu Rev Psychol. 1988; 39:135-68. PMID: 2894197.
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    111. Levy F, Szymusiak R, Satinoff E. Indomethacin pretreatment inhibits fever after anodal, but not cathodal, medial preoptic lesions in rats. Physiol Behav. 1987; 40(1):85-90. PMID: 3615657.
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    112. Szymusiak R, McGinty D. Sleep suppression following kainic acid-induced lesions of the basal forebrain. Exp Neurol. 1986 Dec; 94(3):598-614. PMID: 3780909.
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    113. Szymusiak R, McGinty D. Sleep-related neuronal discharge in the basal forebrain of cats. Brain Res. 1986 Apr 02; 370(1):82-92. PMID: 3708324.
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    114. Szymusiak R, DeMory A, Kittrell EM, Satinoff E. Diurnal changes in thermoregulatory behavior in rats with medial preoptic lesions. Am J Physiol. 1985 Aug; 249(2 Pt 2):R219-27. PMID: 4040714.
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    115. Szymusiak R, Satinoff E. Ambient temperature-dependence of sleep disturbances produced by basal forebrain damage in rats. Brain Res Bull. 1984 Mar; 12(3):295-305. PMID: 6539144.
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    116. Szymusiak R, Satinoff E. Acute thermoregulatory effects of unilateral electrolytic lesions of the medial and lateral preoptic area in rats. Physiol Behav. 1982 Jan; 28(1):161-70. PMID: 7079312.
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    117. Szymusiak R, Satinoff E. Maximal REM sleep time defines a narrower thermoneutral zone than does minimal metabolic rate. Physiol Behav. 1981 Apr; 26(4):687-90. PMID: 7267757.
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    118. Szymusiak R, Satinoff E, Schallert T, Whishaw IQ. Brief skin temperature changes towards thermoneutrality trigger REM sleep in rats. Physiol Behav. 1980 Aug; 25(2):305-11. PMID: 7413838.
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