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Sandy Yushan Chang

Title(s)HS Clinical Instructor, Medicine
SchoolMedicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
Phone3108256301
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia. J Clin Lipidol. 2017 Jul - Aug; 11(4):964-971. Hu X, Dallinga-Thie GM, Hovingh GK, Chang SY, Sandoval NP, Dang TLP, Fukamachi I, Miyashita K, Nakajima K, Murakami M, Fong LG, Ploug M, Young SG, Beigneux AP. PMID: 28666713.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    2. p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses. J Clin Invest. 2013 Oct; 123(10):4489-501. Wang Y, Sharpless N, Chang S. PMID: 24091330.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    3. The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability. Cell Res. 2013 Dec; 23(12):1396-413. Min JN, Tian Y, Xiao Y, Wu L, Li L, Chang S. PMID: 23979016.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    4. Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24. J Lipid Res. 2012 Jun; 53(6):1176-82. Chang SY, Hudon-Miller SE, Yang SH, Jung HJ, Lee JM, Farber E, Subramanian T, Andres DA, Spielmann HP, Hrycyna CA, Young SG, Fong LG. PMID: 22448028.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    5. Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases. J Lipid Res. 2012 Jan; 53(1):77-86. Yang SH, Chang SY, Tu Y, Lawson GW, Bergo MO, Fong LG, Young SG. PMID: 22039581.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    6. Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec; 22(23):4683-93. Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG. PMID: 21976703.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    7. An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. Hum Mol Genet. 2011 Sep 15; 20(18):3537-44. Yang SH, Chang SY, Yin L, Tu Y, Hu Y, Yoshinaga Y, de Jong PJ, Fong LG, Young SG. PMID: 21659336.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    8. Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin. Hum Mol Genet. 2011 Feb 01; 20(3):436-44. Yang SH, Chang SY, Ren S, Wang Y, Andres DA, Spielmann HP, Fong LG, Young SG. PMID: 21088111.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    9. Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5076-81. Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG. PMID: 20145110.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    10. Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Hum Mol Genet. 2010 Apr 15; 19(8):1603-17. Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG. PMID: 20106865.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    11. Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria. J Lipid Res. 2010 Feb; 51(2):400-5. Yang SH, Chang SY, Andres DA, Spielmann HP, Young SG, Fong LG. PMID: 19965595.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    12. Multiple roles for MRE11 at uncapped telomeres. Nature. 2009 Aug 13; 460(7257):914-8. Deng Y, Guo X, Ferguson DO, Chang S. PMID: 19633651.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    13. Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele. J Biol Chem. 2008 Mar 14; 283(11):7094-9. Yang SH, Qiao X, Farber E, Chang SY, Fong LG, Young SG. PMID: 18178963.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    14. HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells. Proc Natl Acad Sci U S A. 2007 Aug 14; 104(33):13432-7. Coffinier C, Hudon SE, Farber EA, Chang SY, Hrycyna CA, Young SG, Fong LG. PMID: 17652517.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    15. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell. 2006 Jul 14; 126(1):49-62. Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, Deng Y, Behringer RR, Chang S. PMID: 16839876.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    16. Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest. 2006 Mar; 116(3):743-52. Fong LG, Ng JK, Lammerding J, Vickers TA, Meta M, Coté N, Gavino B, Qiao X, Chang SY, Young SR, Yang SH, Stewart CL, Lee RT, Bennett CF, Bergo MO, Young SG. PMID: 16511604.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    17. Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell. 2004 Apr; 5(4):375-87. Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. PMID: 15093544.
      View in: PubMed   Mentions: 334     Fields:    Translation:AnimalsCells
    18. Telomerase extracurricular activities. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12520-2. Chang S, DePinho RA. PMID: 12271146.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
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