Scott A John

Title(s)Adjunct Professor, Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Cardiac Na+ -Ca2+ Exchanger: From Structure to Function. Compr Physiol. 2021 12 29; 12(1):2681-2717. Ottolia M, John S, Hazan A, Goldhaber JI. PMID: 34964124; PMCID: PMC8773166.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Modulation of the cardiac Na+-Ca2+ exchanger by cytoplasmic protons: Molecular mechanisms and physiological implications. Cell Calcium. 2020 05; 87:102140. Scranton K, John S, Escobar A, Goldhaber JI, Ottolia M. PMID: 32070924; PMCID: PMC7153995.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Array atomic force microscopy for real-time multiparametric analysis. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):5872-5877. Yang Q, Ma Q, Herum KM, Wang C, Patel N, Lee J, Wang S, Yen TM, Wang J, Tang H, Lo YH, Head BP, Azam F, Xu S, Cauwenberghs G, McCulloch AD, John S, Liu Z, Lal R. PMID: 30850523; PMCID: PMC6442637.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries. J Trauma Acute Care Surg. 2018 11; 85(5):858-866. Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ. PMID: 29847537.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    5. Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger. J Gen Physiol. 2018 02 05; 150(2):245-257. John S, Kim B, Olcese R, Goldhaber JI, Ottolia M. PMID: 29301861; PMCID: PMC5806679.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    6. Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III. J Biol Chem. 2017 06 16; 292(24):9882-9895. Korge P, Calmettes G, John SA, Weiss JN. PMID: 28450391; PMCID: PMC5473241.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    7. Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex II. J Biol Chem. 2017 06 16; 292(24):9896-9905. Korge P, John SA, Calmettes G, Weiss JN. PMID: 28450394; PMCID: PMC5473242.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    8. Real-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells. Physiol Rep. 2017 Feb; 5(3). Ghezzi C, Calmettes G, Morand P, Ribalet B, John S. PMID: 28193781; PMCID: PMC5309568.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    9. Hexokinases and cardioprotection. J Mol Cell Cardiol. 2015 Jan; 78:107-15. Calmettes G, Ribalet B, John S, Korge P, Ping P, Weiss JN. PMID: 25264175; PMCID: PMC4268312.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    10. Hexokinase-mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes. J Gen Physiol. 2013 Oct; 142(4):425-36. Calmettes G, John SA, Weiss JN, Ribalet B. PMID: 24081983; PMCID: PMC3787771.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    11. The cardiac Na+-Ca2+ exchanger has two cytoplasmic ion permeation pathways. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7500-5. John SA, Liao J, Jiang Y, Ottolia M. PMID: 23589872; PMCID: PMC3645563.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    12. Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. PLoS One. 2011 Mar 09; 6(3):e17674. John S, Weiss JN, Ribalet B. PMID: 21408025; PMCID: PMC3052386.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    13. Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1699-704. John SA, Ribalet B, Weiss JN, Philipson KD, Ottolia M. PMID: 21209335; PMCID: PMC3029690.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    14. Vaults are dynamically unconstrained cytoplasmic nanoparticles capable of half vault exchange. ACS Nano. 2010 Dec 28; 4(12):7229-40. Yang J, Kickhoefer VA, Ng BC, Gopal A, Bentolila LA, John S, Tolbert SH, Rome LH. PMID: 21121616; PMCID: PMC3020078.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    15. Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts. Dev Dyn. 2010 Jul; 239(7):1941-9. Chen F, De Diego C, Chang MG, McHarg JL, John S, Klitzner TS, Weiss JN. PMID: 20549739; PMCID: PMC2908293.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    16. Interactions between Ca2+ binding domains of the Na+-Ca2+ exchanger and secondary regulation. Channels (Austin). 2010 May-Jun; 4(3):159-62. Ottolia M, Nicoll DA, John S, Philipson KD. PMID: 20224291.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    17. Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons. Mol Pharmacol. 2009 Jul; 76(1):134-43. Walwyn W, John S, Maga M, Evans CJ, Hales TG. PMID: 19357247; PMCID: PMC2701458.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    18. Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol. 2008 Aug; 295(2):C388-93. Xie Y, Ottolia M, John SA, Chen JN, Philipson KD. PMID: 18550703; PMCID: PMC2518419.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    19. Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity. J Physiol. 2008 Apr 01; 586(7):1833-48. Xie LH, John SA, Ribalet B, Weiss JN. PMID: 18276733; PMCID: PMC2375719.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    20. Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor. Pflugers Arch. 2008 May; 456(2):307-22. John SA, Ottolia M, Weiss JN, Ribalet B. PMID: 18071748; PMCID: PMC4339035.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    21. A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury. PLoS One. 2007 Aug 08; 2(8):e712. Ramachandran S, Xie LH, John SA, Subramaniam S, Lal R. PMID: 17684558; PMCID: PMC1933596.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    22. Shedding light on the Na+/Ca2+ exchanger. Ann N Y Acad Sci. 2007 Mar; 1099:78-85. Ottolia M, John S, Xie Y, Ren X, Philipson KD. PMID: 17446447.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    23. Xenopus oocyte plasma membrane sheets for FRET analysis. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1519-22. Ottolia M, Philipson KD, John S. PMID: 17166939.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    24. Fluorescent Na+-Ca+ exchangers: electrophysiological and optical characterization. J Biol Chem. 2007 Feb 09; 282(6):3695-701. Ottolia M, John S, Ren X, Philipson KD. PMID: 17158867.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands. Prog Biophys Mol Biol. 2007 Jul; 94(3):320-35. Xie LH, John SA, Ribalet B, Weiss JN. PMID: 16837026.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    26. ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2. J Physiol. 2006 Mar 01; 571(Pt 2):303-17. Ribalet B, John SA, Xie LH, Weiss JN. PMID: 16373383; PMCID: PMC1796795.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels. J Gen Physiol. 2005 Dec; 126(6):541-9. Xie LH, John SA, Ribalet B, Weiss JN. PMID: 16316973; PMCID: PMC2266595.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    28. ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2. J Physiol. 2005 Nov 01; 568(Pt 3):931-40. John SA, Weiss JN, Ribalet B. PMID: 16166157; PMCID: PMC1464185.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    29. Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2). J Mol Cell Cardiol. 2005 Jul; 39(1):71-7. Ribalet B, John SA, Xie LH, Weiss JN. PMID: 15978904.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    30. Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel. J Physiol. 2004 Nov 15; 561(Pt 1):159-68. Xie LH, John SA, Ribalet B, Weiss JN. PMID: 15459242; PMCID: PMC1665335.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    31. Conformational changes of the Ca(2+) regulatory site of the Na(+)-Ca(2+) exchanger detected by FRET. Biophys J. 2004 Aug; 87(2):899-906. Ottolia M, Philipson KD, John S. PMID: 15298897; PMCID: PMC1304498.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    32. Mechanism of inward rectification in Kir channels. J Gen Physiol. 2004 May; 123(5):623-5. John SA, Xie LH, Weiss JN. PMID: 15078914; PMCID: PMC2234494.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    33. Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction. J Biol Chem. 2004 Feb 20; 279(8):7037-47. Zhang L, Lee JK, John SA, Uozumi N, Kodama I. PMID: 14660621.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    34. Molecular mechanism for ATP-dependent closure of the K+ channel Kir6.2. J Physiol. 2003 Oct 01; 552(Pt 1):23-34. John SA, Weiss JN, Xie LH, Ribalet B. PMID: 12860923; PMCID: PMC2343328.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    35. Inward rectification by polyamines in mouse Kir2.1 channels: synergy between blocking components. J Physiol. 2003 Jul 01; 550(Pt 1):67-82. Xie LH, John SA, Weiss JN. PMID: 12740427; PMCID: PMC2343018.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    36. Molecular basis for Kir6.2 channel inhibition by adenine nucleotides. Biophys J. 2003 Jan; 84(1):266-76. Ribalet B, John SA, Weiss JN. PMID: 12524280; PMCID: PMC1302608.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    37. The Na+/Ca2+ exchange molecule: an overview. Ann N Y Acad Sci. 2002 Nov; 976:1-10. Philipson KD, Nicoll DA, Ottolia M, Quednau BD, Reuter H, John S, Qiu Z. PMID: 12502528.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    38. Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block. J Gen Physiol. 2002 Jul; 120(1):53-66. Xie LH, John SA, Weiss JN. PMID: 12084775; PMCID: PMC2311403.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
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