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John, Scott A

Title(s)Adjunct Professor, Medicine
SchoolCardiology
Phone3108255766
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Scranton K, John S, Escobar A, Goldhaber JI, Ottolia M. Modulation of the cardiac Na+-Ca2+ exchanger by cytoplasmic protons: Molecular mechanisms and physiological implications. Cell Calcium. 2019 Dec 11; 87:102140. PMID: 32070924.
      View in: PubMed
    2. Yang Q, Ma Q, Herum KM, Wang C, Patel N, Lee J, Wang S, Yen TM, Wang J, Tang H, Lo YH, Head BP, Azam F, Xu S, Cauwenberghs G, McCulloch AD, John S, Liu Z, Lal R. Array atomic force microscopy for real-time multiparametric analysis. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):5872-5877. PMID: 30850523.
      View in: PubMed
    3. Burlew CC, Sumislawski JJ, Behnfield CD, McNutt MK, McCarthy J, Sharpe JP, Croce MA, Bala M, Kashuk J, Spalding MC, Beery PR, John S, Hunt DJ, Harmon L, Stein DM, Callcut R, Wybourn C, Sperry J, Anto V, Dunn J, Veith JP, Brown CVR, Celii A, Zander TL, Coimbra R, Berndtson AE, Moss TZ, Malhotra AK, Hazelton JP, Linden K, West M, Alam HB, Williams AM, Kim J, Inaba K, Moulton S, Choi YM, Warren HL, Collier B, Ball CG, Savage S, Hartwell JL, Cullinane DC, Zielinski MD, Ray-Zack MD, Morse BC, Rhee P, Rutherford EJ, Udekwu P, Reynolds C, Toschlog E, Gondek S, Ju T, Haan JM, Lightwine KL, Kulvatunyou N, Coates B, Khouqeer AF, Todd SR, Zarzaur B, Waller CJ, Kallies KJ, Neideen T, Eddine SBZ, Peck KA, Dunne CE, Kramer K, Bokhari F, Dhillon TS, Galante JM, Cohen MJ. Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries. J Trauma Acute Care Surg. 2018 11; 85(5):858-866. PMID: 29847537.
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    4. John S, Kim B, Olcese R, Goldhaber JI, Ottolia M. Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger. J Gen Physiol. 2018 02 05; 150(2):245-257. PMID: 29301861.
      View in: PubMed
    5. Korge P, Calmettes G, John SA, Weiss JN. Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III. J Biol Chem. 2017 06 16; 292(24):9882-9895. PMID: 28450391.
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    6. Korge P, John SA, Calmettes G, Weiss JN. Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex II. J Biol Chem. 2017 06 16; 292(24):9896-9905. PMID: 28450394.
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    7. Ghezzi C, Calmettes G, Morand P, Ribalet B, John S. Real-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells. Physiol Rep. 2017 Feb; 5(3). PMID: 28193781.
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    8. Calmettes G, Ribalet B, John S, Korge P, Ping P, Weiss JN. Hexokinases and cardioprotection. J Mol Cell Cardiol. 2015 Jan; 78:107-15. PMID: 25264175.
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    9. Calmettes G, John SA, Weiss JN, Ribalet B. Hexokinase-mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes. J Gen Physiol. 2013 Oct; 142(4):425-36. PMID: 24081983.
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    10. John SA, Liao J, Jiang Y, Ottolia M. The cardiac Na+-Ca2+ exchanger has two cytoplasmic ion permeation pathways. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7500-5. PMID: 23589872.
      View in: PubMed
    11. John S, Weiss JN, Ribalet B. Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. PLoS One. 2011 Mar 09; 6(3):e17674. PMID: 21408025.
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    12. John SA, Ribalet B, Weiss JN, Philipson KD, Ottolia M. Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1699-704. PMID: 21209335.
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    13. Yang J, Kickhoefer VA, Ng BC, Gopal A, Bentolila LA, John S, Tolbert SH, Rome LH. Vaults are dynamically unconstrained cytoplasmic nanoparticles capable of half vault exchange. ACS Nano. 2010 Dec 28; 4(12):7229-40. PMID: 21121616.
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    14. Chen F, De Diego C, Chang MG, McHarg JL, John S, Klitzner TS, Weiss JN. Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts. Dev Dyn. 2010 Jul; 239(7):1941-9. PMID: 20549739.
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    15. Ottolia M, Nicoll DA, John S, Philipson KD. Interactions between Ca2+ binding domains of the Na+-Ca2+ exchanger and secondary regulation. Channels (Austin). 2010 May-Jun; 4(3):159-62. PMID: 20224291.
      View in: PubMed
    16. Walwyn W, John S, Maga M, Evans CJ, Hales TG. Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons. Mol Pharmacol. 2009 Jul; 76(1):134-43. PMID: 19357247.
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    17. Xie Y, Ottolia M, John SA, Chen JN, Philipson KD. Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. Am J Physiol Cell Physiol. 2008 Aug; 295(2):C388-93. PMID: 18550703.
      View in: PubMed
    18. Xie LH, John SA, Ribalet B, Weiss JN. Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity. J Physiol. 2008 Apr 01; 586(7):1833-48. PMID: 18276733.
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    19. John SA, Ottolia M, Weiss JN, Ribalet B. Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor. Pflugers Arch. 2008 May; 456(2):307-22. PMID: 18071748.
      View in: PubMed
    20. Ramachandran S, Xie LH, John SA, Subramaniam S, Lal R. A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury. PLoS One. 2007 Aug 08; 2(8):e712. PMID: 17684558.
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    21. Ottolia M, John S, Xie Y, Ren X, Philipson KD. Shedding light on the Na+/Ca2+ exchanger. Ann N Y Acad Sci. 2007 Mar; 1099:78-85. PMID: 17446447.
      View in: PubMed
    22. Ottolia M, Philipson KD, John S. Xenopus oocyte plasma membrane sheets for FRET analysis. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1519-22. PMID: 17166939.
      View in: PubMed
    23. Ottolia M, John S, Ren X, Philipson KD. Fluorescent Na+-Ca+ exchangers: electrophysiological and optical characterization. J Biol Chem. 2007 Feb 09; 282(6):3695-701. PMID: 17158867.
      View in: PubMed
    24. Xie LH, John SA, Ribalet B, Weiss JN. Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands. Prog Biophys Mol Biol. 2007 Jul; 94(3):320-35. PMID: 16837026.
      View in: PubMed
    25. Ribalet B, John SA, Xie LH, Weiss JN. ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2. J Physiol. 2006 Mar 01; 571(Pt 2):303-17. PMID: 16373383.
      View in: PubMed
    26. Xie LH, John SA, Ribalet B, Weiss JN. Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels. J Gen Physiol. 2005 Dec; 126(6):541-9. PMID: 16316973.
      View in: PubMed
    27. John SA, Weiss JN, Ribalet B. ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2. J Physiol. 2005 Nov 01; 568(Pt 3):931-40. PMID: 16166157.
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    28. Ribalet B, John SA, Xie LH, Weiss JN. Regulation of the ATP-sensitive K channel Kir6.2 by ATP and PIP(2). J Mol Cell Cardiol. 2005 Jul; 39(1):71-7. PMID: 15978904.
      View in: PubMed
    29. Xie LH, John SA, Ribalet B, Weiss JN. Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel. J Physiol. 2004 Nov 15; 561(Pt 1):159-68. PMID: 15459242.
      View in: PubMed
    30. Ottolia M, Philipson KD, John S. Conformational changes of the Ca(2+) regulatory site of the Na(+)-Ca(2+) exchanger detected by FRET. Biophys J. 2004 Aug; 87(2):899-906. PMID: 15298897.
      View in: PubMed
    31. John SA, Xie LH, Weiss JN. Mechanism of inward rectification in Kir channels. J Gen Physiol. 2004 May; 123(5):623-5. PMID: 15078914.
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    32. Zhang L, Lee JK, John SA, Uozumi N, Kodama I. Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction. J Biol Chem. 2004 Feb 20; 279(8):7037-47. PMID: 14660621.
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    33. John SA, Weiss JN, Xie LH, Ribalet B. Molecular mechanism for ATP-dependent closure of the K+ channel Kir6.2. J Physiol. 2003 Oct 01; 552(Pt 1):23-34. PMID: 12860923.
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    34. Xie LH, John SA, Weiss JN. Inward rectification by polyamines in mouse Kir2.1 channels: synergy between blocking components. J Physiol. 2003 Jul 01; 550(Pt 1):67-82. PMID: 12740427.
      View in: PubMed
    35. Ribalet B, John SA, Weiss JN. Molecular basis for Kir6.2 channel inhibition by adenine nucleotides. Biophys J. 2003 Jan; 84(1):266-76. PMID: 12524280.
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    36. Philipson KD, Nicoll DA, Ottolia M, Quednau BD, Reuter H, John S, Qiu Z. The Na+/Ca2+ exchange molecule: an overview. Ann N Y Acad Sci. 2002 Nov; 976:1-10. PMID: 12502528.
      View in: PubMed
    37. Xie LH, John SA, Weiss JN. Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block. J Gen Physiol. 2002 Jul; 120(1):53-66. PMID: 12084775.
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