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Sherven Sharma

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
Address555 Westwood Plaza MAILROOM
Los Angeles CA 90024
Phone(310) 478-3711x41863
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    Collapse Research 
    Collapse Research Activities and Funding
    Programming Durable Immune Responses in Lung Cancer
    VA I01BX003171Oct 1, 2016 - Sep 30, 2020
    Role: Principal Investigator
    Modulating Immune Responses in Lung Cancer
    VA I01BX000905Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator
    Novel Immune Pathways for Lung Cancer Therapy
    NIH/NCI R01CA126944Mar 1, 2008 - Jan 31, 2014
    Role: Principal Investigator
    SLC/6Ckine Immunotherapy for Cancer
    NIH/NCI K01CA090242Jun 13, 2002 - May 31, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CCL21 Programs Immune Activity in Tumor Microenvironment. Adv Exp Med Biol. 2020; 1231:67-78. Sharma S, Kadam P, Dubinett S. PMID: 32060847.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy. Cancer Res. 2019 Oct 01; 79(19):5022-5033. Krysan K, Tran LM, Grimes BS, Fishbein GA, Seki A, Gardner BK, Walser TC, Salehi-Rad R, Yanagawa J, Lee JM, Sharma S, Aberle DR, Spira AE, Elashoff DA, Wallace WD, Fishbein MC, Dubinett SM. PMID: 31142513.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    3. Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Res. 2018 04 15; 78(8):1986-1999. Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM. PMID: 29431637.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    4. Use of a Novel Polymer in an Animal Model of Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2018 01; 158(1):110-117. Pellionisz PA, Lin Y, Mallen-St Clair J, Luo J, Suwarnasarn A, Schaue D, Elashoff DA, Palma-Diaz F, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 28895464.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL. Sci Rep. 2017 08 23; 7(1):9192. Tan YC, Mirzapoiazova T, Won BM, Zhu L, Srivastava MK, Vokes EE, Husain AN, Batra SK, Sharma S, Salgia R. PMID: 28835699.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration. Clin Cancer Res. 2017 Aug 15; 23(16):4556-4568. Lee JM, Lee MH, Garon E, Goldman JW, Salehi-Rad R, Baratelli FE, Schaue D, Wang G, Rosen F, Yanagawa J, Walser TC, Lin Y, Park SJ, Adams S, Marincola FM, Tumeh PC, Abtin F, Suh R, Reckamp KL, Lee G, Wallace WD, Lee S, Zeng G, Elashoff DA, Sharma S, Dubinett SM. PMID: 28468947.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    7. p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma. Oral Oncol. 2016 09; 60:81-9. Lin Y, Mallen-St Clair J, Wang G, Luo J, Palma-Diaz F, Lai C, Elashoff DA, Sharma S, Dubinett SM, St John M. PMID: 27531877.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. p53 modulates NF-κB mediated epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma. Oral Oncol. 2015 Oct; 51(10):921-8. Lin Y, Mallen-St Clair J, Luo J, Sharma S, Dubinett S, St John M. PMID: 26306422.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. GITR agonist enhances vaccination responses in lung cancer. Oncoimmunology. 2015 Apr; 4(4):e992237. Zhu LX, Davoodi M, Srivastava MK, Kachroo P, Lee JM, St John M, Harris-White M, Huang M, Strieter RM, Dubinett S, Sharma S. PMID: 26137407.
      View in: PubMed   Mentions:
    10. Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway. J Cancer Sci Ther. 2014 Nov; 6(11):468-477. Lee MH, Kachroo P, Pagano PC, Yanagawa J, Wang G, Walser TC, Krysan K, Sharma S, John MS, Dubinett SM, Lee JM. PMID: 26523208.
      View in: PubMed   Mentions:
    11. Th17 cells in inflammation and autoimmunity. Autoimmun Rev. 2014 Dec; 13(12):1174-81. Singh RP, Hasan S, Sharma S, Nagra S, Yamaguchi DT, Wong DT, Hahn BH, Hossain A. PMID: 25151974.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    12. A cytokine-delivering polymer is effective in reducing tumor burden in a head and neck squamous cell carcinoma murine model. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):447-53. Lin Y, Luo J, Zhu WE, Srivastava M, Schaue D, Elashoff DA, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 24825873.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    13. CCL21 Cancer Immunotherapy. Cancers (Basel). 2014 May 07; 6(2):1098-110. Lin Y, Sharma S, John MS. PMID: 24810425.
      View in: PubMed   Mentions:
    14. PGE2-driven expression of c-Myc and oncomiR-17-92 contributes to apoptosis resistance in NSCLC. Mol Cancer Res. 2014 May; 12(5):765-74. Krysan K, Kusko R, Grogan T, O'Hearn J, Reckamp KL, Walser TC, Garon EB, Lenburg ME, Sharma S, Spira AE, Elashoff D, Dubinett SM. PMID: 24469837.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    15. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. J Exp Clin Cancer Res. 2013 Nov 25; 32:97. Kachroo P, Lee MH, Zhang L, Baratelli F, Lee G, Srivastava MK, Wang G, Walser TC, Krysan K, Sharma S, Dubinett SM, Lee JM. PMID: 24274066.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    16. Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer. Am J Transl Res. 2013; 5(5):481-96. Krysan K, Cui X, Gardner BK, Reckamp KL, Wang X, Hong L, Walser TC, Rodriguez NL, Pagano PC, Garon EB, Brothers JF, Elashoff D, Lee JM, Spira AE, Sharma S, Fishbein MC, Dubinett SM. PMID: 23977408.
      View in: PubMed   Mentions:
    17. Effect of epigenetic histone modifications on E-cadherin splicing and expression in lung cancer. Am J Cancer Res. 2013; 3(4):374-89. Liao W, Jordaan G, Srivastava MK, Dubinett S, Sharma S, Sharma S. PMID: 23977447.
      View in: PubMed   Mentions:
    18. The role of miRNA in inflammation and autoimmunity. Autoimmun Rev. 2013 Oct; 12(12):1160-5. Singh RP, Massachi I, Manickavel S, Singh S, Rao NP, Hasan S, Mc Curdy DK, Sharma S, Wong D, Hahn BH, Rehimi H. PMID: 23860189.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimals
    19. TLR3 agonists and proinflammatory antitumor activities. Expert Opin Ther Targets. 2013 May; 17(5):481-3. Sharma S, Zhu L, Davoodi M, Harris-White M, Lee JM, St John M, Salgia R, Dubinett S. PMID: 23506058.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    20. CCL21 Chemokine Therapy for Lung Cancer. Int Trends Immun. 2013 Jan; 1(1):10-15. Sharma S, Zhu L, Srivastava MK, Harris-White M, Huang M, Lee JM, Rosen F, Lee G, Wang G, Kickhoefer V, Rome LH, Baratelli F, St John M, Reckamp K, Chul-Yang S, Hillinger S, Strieter R, Dubinett S. PMID: 25264541.
      View in: PubMed   Mentions:
    21. Targeting MDSCs enhance therapeutic vaccination responses against lung cancer. Oncoimmunology. 2012 Dec 01; 1(9):1650-1651. Srivastava MK, Dubinett S, Sharma S. PMID: 23264925.
      View in: PubMed   Mentions:
    22. CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):940-1. Sharma S, Dubinett S, Salgia R. PMID: 23155211.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer. Immunotargets Ther. 2012 Oct 01; 2012(1):7-12. Srivastava MK, Zhu L, Harris-White M, Huang M, St John M, Lee JM, Salgia R, Cameron RB, Strieter R, Dubinett S, Sharma S. PMID: 24791250.
      View in: PubMed   Mentions:
    24. Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLoS One. 2012; 7(7):e40677. Srivastava MK, Zhu L, Harris-White M, Kar UK, Kar U, Huang M, Johnson MF, Lee JM, Elashoff D, Strieter R, Dubinett S, Sharma S. PMID: 22815789.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCellsPHPublic Health
    25. Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice. PLoS One. 2012; 7(7):e38553. Kar UK, Jiang J, Champion CI, Salehi S, Srivastava M, Sharma S, Rabizadeh S, Niazi K, Kickhoefer V, Rome LH, Kelly KA. PMID: 22808011.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells. Otolaryngol Head Neck Surg. 2012 Oct; 147(4):726-32. Dennis M, Wang G, Luo J, Lin Y, Dohadwala M, Abemayor E, Elashoff DA, Sharma S, Dubinett SM, St John MA. PMID: 22568942.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    27. A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model. Arch Otolaryngol Head Neck Surg. 2012 Apr; 138(4):412-7. Hu D, Lau OD, Wang L, Wang G, Schaue D, Zhu L, Huang M, Lin Y, Dennis M, Abemayor E, Elashoff DA, Dubinett SM, McBride WH, Sharma S, Wu B, St John MA. PMID: 22508626.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    28. Myeloid suppressor cells and immune modulation in lung cancer. Immunotherapy. 2012 Mar; 4(3):291-304. Srivastava MK, Andersson Å, Zhu L, Harris-White M, Lee JM, Dubinett S, Sharma S. PMID: 22401635.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    29. MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer. Expert Opin Biol Ther. 2011 Aug; 11(8):987-90. Sharma S, Srivastava MK, Harris-White M, Lee JM, Dubinett S. PMID: 21711210.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer. Clin Cancer Res. 2011 Jun 01; 17(11):3660-72. Andersson A, Srivastava MK, Harris-White M, Huang M, Zhu L, Elashoff D, Strieter RM, Dubinett SM, Sharma S. PMID: 21636553.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    31. Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth. PLoS One. 2011 May 03; 6(5):e18758. Kar UK, Srivastava MK, Andersson A, Baratelli F, Huang M, Kickhoefer VA, Dubinett SM, Rome LH, Sharma S. PMID: 21559281.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    32. Chemokines: can effector cells be redirected to the site of the tumor? Cancer J. 2010 Jul-Aug; 16(4):325-35. Dubinett SM, Lee JM, Sharma S, Mulé JJ. PMID: 20693843.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    33. PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer. Am J Transl Res. 2010 Jun 30; 2(4):356-67. Baratelli F, Lee JM, Hazra S, Lin Y, Walser TC, Schaue D, Pak PS, Elashoff D, Reckamp K, Zhang L, Fishbein MC, Sharma S, Dubinett SM. PMID: 20733946.
      View in: PubMed   Mentions:
    34. Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clin Cancer Res. 2009 Nov 15; 15(22):6820-9. Yanagawa J, Walser TC, Zhu LX, Hong L, Fishbein MC, Mah V, Chia D, Goodglick L, Elashoff DA, Luo J, Magyar CE, Dohadwala M, Lee JM, St John MA, Strieter RM, Sharma S, Dubinett SM. PMID: 19887480.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    35. Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res. 2009 Oct 01; 15(19):6018-27. St John MA, Dohadwala M, Luo J, Wang G, Lee G, Shih H, Heinrich E, Krysan K, Walser T, Hazra S, Zhu L, Lai C, Abemayor E, Fishbein M, Elashoff DA, Sharma S, Dubinett SM. PMID: 19789323.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    36. Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment. Immunotherapy. 2009 Sep; 1(5):721-5. Dubinett S, Sharma S. PMID: 20636013.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    37. The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer. PLoS One. 2009 Jun 12; 4(6):e5884. Basak SK, Veena MS, Oh S, Huang G, Srivatsan E, Huang M, Sharma S, Batra RK. PMID: 19536353.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    38. CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells. Lab Invest. 2009 Aug; 89(8):875-86. Veena MS, Qin M, Andersson A, Sharma S, Batra RK. PMID: 19506548.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    39. Adenovirus E3 proteins help tumors to evade innate and adaptive immune responses. . 2009 Jun; 8(12):1133-5. Sharma S, Andersson A. PMID: 19458480.
      View in: PubMed   Mentions:
    40. IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer. J Immunol. 2009 Jun 01; 182(11):6951-8. Andersson A, Yang SC, Huang M, Zhu L, Kar UK, Batra RK, Elashoff D, Strieter RM, Dubinett SM, Sharma S. PMID: 19454692.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    41. Smoking and lung cancer: the role of inflammation. Proc Am Thorac Soc. 2008 Dec 01; 5(8):811-5. Walser T, Cui X, Yanagawa J, Lee JM, Heinrich E, Lee G, Sharma S, Dubinett SM. PMID: 19017734.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    42. Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer. J Transl Med. 2008 Jul 22; 6:38. Baratelli F, Takedatsu H, Hazra S, Peebles K, Luo J, Kurimoto PS, Zeng G, Batra RK, Sharma S, Dubinett SM, Lee JM. PMID: 18644162.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    43. Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment. Crit Rev Oncol Hematol. 2008 Jun; 66(3):208-17. Lee JM, Yanagawa J, Peebles KA, Sharma S, Mao JT, Dubinett SM. PMID: 18304833.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    44. Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. J Thorac Oncol. 2008 Feb; 3(2):117-24. Reckamp KL, Gardner BK, Figlin RA, Elashoff D, Krysan K, Dohadwala M, Mao J, Sharma S, Inge L, Rajasekaran A, Dubinett SM. PMID: 18303430.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    45. Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. J Thorac Oncol. 2008 Feb; 3(2):107-10. Krysan K, Lee JM, Dohadwala M, Gardner BK, Reckamp KL, Garon E, St John M, Sharma S, Dubinett SM. PMID: 18303428.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    46. The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer. PPAR Res. 2008; 2008:790568. Hazra S, Peebles KA, Sharma S, Mao JT, Dubinett SM. PMID: 18769553.
      View in: PubMed   Mentions:
    47. Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Rev Anticancer Ther. 2007 Oct; 7(10):1405-21. Peebles KA, Lee JM, Mao JT, Hazra S, Reckamp KL, Krysan K, Dohadwala M, Heinrich EL, Walser TC, Cui X, Baratelli FE, Garon E, Sharma S, Dubinett SM. PMID: 17944566.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    48. EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2007 Nov; 37(5):578-88. Liu M, Yang SC, Sharma S, Luo J, Cui X, Peebles KA, Huang M, Sato M, Ramirez RD, Shay JW, Minna JD, Dubinett SM. PMID: 17600311.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    49. Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase. Mol Pharmacol. 2007 Jun; 71(6):1715-20. Hazra S, Batra RK, Tai HH, Sharma S, Cui X, Dubinett SM. PMID: 17412838.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    50. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 2006 May 15; 66(10):5338-45. Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, Lin Y, Goodglick L, Krysan K, Fishbein MC, Hong L, Lai C, Cameron RB, Gemmill RM, Drabkin HA, Dubinett SM. PMID: 16707460.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansCells
    51. The potential and rationale for COX-2 inhibitors in lung cancer. Anticancer Agents Med Chem. 2006 May; 6(3):209-20. Krysan K, Reckamp KL, Sharma S, Dubinett SM. PMID: 16712449.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    52. IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer. Biochem Biophys Res Commun. 2006 May 19; 343(4):995-1001. Cui X, Yang SC, Sharma S, Heuze-Vourc'h N, Dubinett SM. PMID: 16574063.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    53. Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res. 2006 Mar 15; 66(6):3205-13. Yang SC, Batra RK, Hillinger S, Reckamp KL, Strieter RM, Dubinett SM, Sharma S. PMID: 16540672.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    54. Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance. Blood. 2006 Jun 01; 107(11):4484-90. Hoang B, Zhu L, Shi Y, Frost P, Yan H, Sharma S, Sharma S, Goodglick L, Dubinett S, Lichtenstein A. PMID: 16497971.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    55. CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis. J Immunol. 2006 Feb 01; 176(3):1456-64. Pan J, Burdick MD, Belperio JA, Xue YY, Gerard C, Sharma S, Dubinett SM, Strieter RM. PMID: 16424173.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    56. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clin Cancer Res. 2005 Nov 01; 11(21):7674-82. Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S. PMID: 16278387.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    57. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol. 2005 Aug 01; 175(3):1483-90. Baratelli F, Lin Y, Zhu L, Yang SC, Heuzé-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM. PMID: 16034085.
      View in: PubMed   Mentions: 165     Fields:    Translation:HumansCells
    58. IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression. Biochem Biophys Res Commun. 2005 Jul 29; 333(2):470-5. Heuzé-Vourc'h N, Liu M, Dalwadi H, Baratelli FE, Zhu L, Goodglick L, Põld M, Sharma S, Ramirez RD, Shay JW, Minna JD, Strieter RM, Dubinett SM. PMID: 15950941.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    59. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res. 2005 Jul 15; 65(14):6275-81. Krysan K, Reckamp KL, Dalwadi H, Sharma S, Rozengurt E, Dohadwala M, Dubinett SM. PMID: 16024629.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    60. Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. J Immunol. 2005 Jul 15; 175(2):813-9. Sharma S, Zhu L, Yang SC, Zhang L, Lin J, Hillinger S, Gardner B, Reckamp K, Strieter RM, Huang M, Batra RK, Dubinett SM. PMID: 16002678.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    61. Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer. Clin Lung Cancer. 2005 Jul; 7(1):30-9. Mao JT, Cui X, Reckamp K, Liu M, Krysan K, Dalwadi H, Sharma S, Hazra S, Strieter R, Gardner B, Dubinett SM. PMID: 16098242.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    62. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res. 2005 Jun 15; 65(12):5211-20. Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, Baratelli F, Huang M, Batra RK, Dubinett SM. PMID: 15958566.
      View in: PubMed   Mentions: 138     Fields:    Translation:AnimalsCells
    63. PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells. J Leukoc Biol. 2005 Aug; 78(2):555-64. Baratelli F, Krysan K, Heuzé-Vourc'h N, Zhu L, Escuadro B, Sharma S, Reckamp K, Dohadwala M, Dubinett SM. PMID: 15908458.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    64. The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone. Anticancer Res. 2005 Jan-Feb; 25(1A):107-15. Gamradt SC, Feeley BT, Liu NQ, Roostaeian J, Lin YQ, Zhu LX, Sharma S, Dubinett SM, Lieberman JR. PMID: 15816526.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    65. Gene transfer mediated by native versus fibroblast growth factor-retargeted adenoviral vectors into lung cancer cells. Am J Respir Cell Mol Biol. 2005 Mar; 32(3):211-7. Qin M, Escuadro B, Sharma S, Batra RK. PMID: 15626775.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    66. CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer. Ann N Y Acad Sci. 2004 Dec; 1028:351-60. Strieter RM, Belperio JA, Burdick MD, Sharma S, Dubinett SM, Keane MP. PMID: 15650260.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    67. Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix. J Immunol. 2004 Nov 01; 173(9):5458-66. Baratelli FE, Heuzé-Vourc'h N, Krysan K, Dohadwala M, Riedl K, Sharma S, Dubinett SM. PMID: 15494493.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    68. A novel role for the coxsackie adenovirus receptor in mediating tumor formation by lung cancer cells. Cancer Res. 2004 Sep 15; 64(18):6377-80. Qin M, Escuadro B, Dohadwala M, Sharma S, Batra RK. PMID: 15374942.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    69. Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Res. 2004 Sep 15; 64(18):6359-62. Krysan K, Dalwadi H, Sharma S, Põld M, Dubinett S. PMID: 15374938.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    70. Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer. Cancer Res. 2004 Sep 15; 64(18):6549-55. Põld M, Krysan K, Põld A, Dohadwala M, Heuze-Vourc'h N, Mao JT, Riedl KL, Sharma S, Dubinett SM. PMID: 15374967.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    71. Multifaceted roles of cyclooxygenase-2 in lung cancer. Drug Resist Updat. 2004 Jun; 7(3):169-84. Riedl K, Krysan K, Põld M, Dalwadi H, Heuze-Vourc'h N, Dohadwala M, Liu M, Cui X, Figlin R, Mao JT, Strieter R, Sharma S, Dubinett SM. PMID: 15296859.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    72. Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. J Biol Chem. 2004 Jul 02; 279(27):28315-9. Zhang L, Keane MP, Zhu LX, Sharma S, Rozengurt E, Strieter RM, Dubinett SM, Huang M. PMID: 15133032.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    73. Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer. Chest. 2004 May; 125(5 Suppl):140S. Krysan K, Dohadwala M, Luo J, Lin Y, Zhu L, Heuze-Vourc'h N, Goodglick L, Merchant F, Seligson D, Pold M, Strieter R, Sharma S, Dubinett S. PMID: 15136466.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    74. Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clin Cancer Res. 2004 Apr 15; 10(8):2891-901. Yang SC, Hillinger S, Riedl K, Zhang L, Zhu L, Huang M, Atianzar K, Kuo BY, Gardner B, Batra RK, Strieter RM, Dubinett SM, Sharma S. PMID: 15102698.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    75. Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Res. 2004 Mar 01; 64(5):1853-60. Põld M, Zhu LX, Sharma S, Burdick MD, Lin Y, Lee PP, Põld A, Luo J, Krysan K, Dohadwala M, Mao JT, Batra RK, Strieter RM, Dubinett SM. PMID: 14996749.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    76. Cocaine modulates cytokine and enhances tumor growth through sigma receptors. J Neuroimmunol. 2004 Feb; 147(1-2):95-8. Gardner B, Zhu LX, Roth MD, Tashkin DP, Dubinett SM, Sharma S. PMID: 14741436.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    77. EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model. J Immunol. 2003 Dec 15; 171(12):6457-65. Hillinger S, Yang SC, Zhu L, Huang M, Duckett R, Atianzar K, Batra RK, Strieter RM, Dubinett SM, Sharma S. PMID: 14662845.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    78. COX-2-dependent stabilization of survivin in non-small cell lung cancer. FASEB J. 2004 Jan; 18(1):206-8. Krysan K, Merchant FH, Zhu L, Dohadwala M, Luo J, Lin Y, Heuze-Vourc'h N, Põld M, Seligson D, Chia D, Goodglick L, Wang H, Strieter R, Sharma S, Dubinett S. PMID: 14597555.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    79. Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells. Mol Cancer. 2003 Nov 02; 2:35. Riedl K, Baratelli F, Batra RK, Yang SC, Luo J, Escuadro B, Figlin R, Strieter R, Sharma S, Dubinett S. PMID: 14613584.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    80. Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Hum Gene Ther. 2003 Nov 01; 14(16):1511-24. Sharma S, Batra RK, Yang SC, Hillinger S, Zhu L, Atianzar K, Strieter RM, Riedl K, Huang M, Dubinett SM. PMID: 14577913.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    81. Coxsackievirus adenovirus receptor expression predicts the efficiency of adenoviral gene transfer into non-small cell lung cancer xenografts. Clin Cancer Res. 2003 Oct 15; 9(13):4992-9. Qin M, Chen S, Yu T, Escuadro B, Sharma S, Batra RK. PMID: 14581374.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    82. Methanandamide increases COX-2 expression and tumor growth in murine lung cancer. FASEB J. 2003 Nov; 17(14):2157-9. Gardner B, Zhu LX, Sharma S, Tashkin DP, Dubinett SM. PMID: 12958151.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    83. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72. Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. PMID: 12941836.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    84. SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10. Mol Cancer. 2003 Apr 15; 2:22. Sharma S, Yang SC, Hillinger S, Zhu LX, Huang M, Batra RK, Lin JF, Burdick MD, Strieter RM, Dubinett SM. PMID: 12740040.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    85. IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity. J Immunol. 2003 Apr 01; 170(7):3585-91. Zhu LX, Sharma S, Gardner B, Escuadro B, Atianzar K, Tashkin DP, Dubinett SM. PMID: 12646621.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    86. Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res. 2003 Mar; 9(3):961-8. Sharma S, Stolina M, Yang SC, Baratelli F, Lin JF, Atianzar K, Luo J, Zhu L, Lin Y, Huang M, Dohadwala M, Batra RK, Dubinett SM. PMID: 12631593.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    87. Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells. Cancer Res. 2003 Feb 15; 63(4):766-70. Heuze-Vourc'h N, Zhu L, Krysan K, Batra RK, Sharma S, Dubinett SM. PMID: 12591723.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    88. Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism. Cancer Res. 2003 Feb 01; 63(3):642-6. Batra RK, Lin Y, Sharma S, Dohadwala M, Luo J, Pold M, Dubinett SM. PMID: 12566308.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    89. Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer. Methods Mol Med. 2003; 75:723-36. Sharma S, Huang M, Dohadwala M, Pold M, Batra RK, Dubinett SM. PMID: 12407775.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    90. Identifying obstacles to viral gene therapy for lung cancer. Malignant pleural effusions as a paradigm. Methods Mol Med. 2003; 75:545-59. Batra RK, Bernal RM, Sharma S. PMID: 12407763.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    91. Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models. Methods Mol Med. 2003; 75:711-22. Sharma S, Yang SC, Batra RK, Dubinett SM. PMID: 12407774.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    92. Cyclooxygenase-2 in lung cancer. Prog Exp Tumor Res. 2003; 37:138-62. Dubinett SM, Sharma S, Huang M, Dohadwala M, Pold M, Mao JT. PMID: 12795053.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    93. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem. 2002 Dec 27; 277(52):50828-33. Dohadwala M, Batra RK, Luo J, Lin Y, Krysan K, Pold M, Sharma S, Dubinett SM. PMID: 12393872.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    94. Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu. Clin Cancer Res. 2002 Jun; 8(6):1915-23. Bernal RM, Sharma S, Gardner BK, Douglas JT, Bergelson JM, Dubinett SM, Batra RK. PMID: 12060636.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    95. Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4. Blood. 2002 Apr 15; 99(8):2869-79. Basak SK, Harui A, Stolina M, Sharma S, Mitani K, Dubinett SM, Roth MD. PMID: 11929777.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    96. IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis. J Clin Invest. 2002 Apr; 109(7):931-7. Huang M, Sharma S, Zhu LX, Keane MP, Luo J, Zhang L, Burdick MD, Lin YQ, Dohadwala M, Gardner B, Batra RK, Strieter RM, Dubinett SM. PMID: 11927620.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    97. Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta. Biochem Biophys Res Commun. 2002 Jan 11; 290(1):91-6. Gardner B, Zu LX, Sharma S, Liu Q, Makriyannis A, Tashkin DP, Dubinett SM. PMID: 11779138.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
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