Susana Vacas

Title(s)Assistant Professor-in-Residence, Anesthesiology
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    Blood Brain Barrier Dysfunction and Perioperative Neurocognitive Disorders in older adults
    NIH R21AG070269Sep 11, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Mechanisms Mediating Postoperative Neurocognitive Disorders
    NIH K23GM132795Sep 20, 2019 - Aug 31, 2024
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Perioperative Brain Health in the Older Adult: A Patient Safety Imperative. Anesth Analg. 2022 May 19. Vacas S, Canales C, Deiner SG, Cole DJ. PMID: 35584550.
      View in: PubMed   Mentions:
    2. Impaired Glymphatic System Actions in Obstructive Sleep Apnea Adults. Front Neurosci. 2022; 16:884234. Roy B, Nunez A, Aysola RS, Kang DW, Vacas S, Kumar R. PMID: 35600625; PMCID: PMC9120580.
      View in: PubMed   Mentions:
    3. Brain regional homogeneity changes after short-term positive airway pressure treatment in patients with obstructive sleep apnea. Sleep Med. 2022 03; 91:12-20. Song X, Roy B, Vacas S, Woo MA, Kang DW, Aysola RS, Kumar R. PMID: 35245787.
      View in: PubMed   Mentions:
    4. Association of Cognitive Decline With Anesthesia and Surgery in Older Patients-Reply. JAMA. 2021 12 28; 326(24):2531. Vacas S, Cole DJ, Cannesson M. PMID: 34962534.
      View in: PubMed   Mentions:
    5. Regional brain tissue changes in patients with cystic fibrosis. J Transl Med. 2021 10 09; 19(1):419. Roy B, Woo MS, Vacas S, Eshaghian P, Rao AP, Kumar R. PMID: 34627274; PMCID: PMC8502335.
      View in: PubMed   Mentions:    Fields:    
    6. Cognitive Decline Associated With Anesthesia and Surgery in Older Patients. JAMA. 2021 Aug 02. Vacas S, Cole DJ, Cannesson M. PMID: 34338712; PMCID: PMC8807795.
      View in: PubMed   Mentions:    Fields:    
    7. Loss of spectral alpha power during spine surgery: what could be wrong? J Clin Monit Comput. 2021 12; 35(6):1531-1533. Lobo FA, Vacas S, Naranjo M. PMID: 33991269; PMCID: PMC8545759.
      View in: PubMed   Mentions:
    8. Roadmap for Conducting Neuroscience Research in the COVID-19 Era and Beyond: Recommendations From the SNACC Research Committee. J Neurosurg Anesthesiol. 2021 Apr 01; 33(2):100-106. Vlisides PE, Vogt KM, Pal D, Schnell E, Armstead WM, Brambrink AM, Kuo P, Nelson P, Vacas S, Goettel N, Aglio LS, Farag E, Gorji R, García PS, Koerner IP. PMID: 33660699; PMCID: PMC8310904.
      View in: PubMed   Mentions:
    9. Brain Structural Changes in Patients with Pulmonary Arterial Hypertension. J Neuroimaging. 2021 05; 31(3):524-531. Roy B, Vacas S, Ehlert L, McCloy K, Saggar R, Kumar R. PMID: 33565204; PMCID: PMC8119315.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Does electroencephalographic burst suppression still play a role in the perioperative setting? Best Pract Res Clin Anaesthesiol. 2021 Jul; 35(2):159-169. Lobo FA, Vacas S, Rossetti AO, Robba C, Taccone FS. PMID: 34030801; PMCID: PMC8330552.
      View in: PubMed   Mentions:
    11. Interventions to improve perioperative neurologic outcomes. Curr Opin Anaesthesiol. 2020 Oct; 33(5):661-667. Vandiver MS, Vacas S. PMID: 32769748; PMCID: PMC8281358.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Seen and Ignored: Are We Undermining Studies of Brain Health Interventions Before We Start? Anesth Analg. 2020 08; 131(2):464-465. Vacas S, Hudson AE. PMID: 32665496; PMCID: PMC7717529.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Anesthetic Management Using Multiple Closed-loop Systems and Delayed Neurocognitive Recovery: A Randomized Controlled Trial. Anesthesiology. 2020 02; 132(2):253-266. Joosten A, Rinehart J, Bardaji A, Van der Linden P, Jame V, Van Obbergh L, Alexander B, Cannesson M, Vacas S, Liu N, Slama H, Barvais L. PMID: 31939839; PMCID: PMC7517610.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    14. Noninvasive Monitoring and Potential for Patient Outcome. J Cardiothorac Vasc Anesth. 2019 08; 33 Suppl 1:S76-S83. Vacas S, Cannesson M. PMID: 31279357; PMCID: PMC6783129.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Electroencephalographic Arousal Patterns Under Dexmedetomidine Sedation. Anesth Analg. 2018 10; 127(4):951-959. Sleigh JW, Vacas S, Flexman AM, Talke PO. PMID: 29933272.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    16. Improving Perioperative Outcomes Through Minimally Invasive and Non-invasive Hemodynamic Monitoring Techniques. Front Med (Lausanne). 2018; 5:144. Yamada T, Vacas S, Gricourt Y, Cannesson M. PMID: 29868596; PMCID: PMC5966660.
      View in: PubMed   Mentions: 5  
    17. Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein-induced Inflammation through a Vagomimetic Action in Mice. Anesthesiology. 2018 05; 128(5):921-931. Hu J, Vacas S, Feng X, Lutrin D, Uchida Y, Lai IK, Maze M. PMID: 29252509; PMCID: PMC6445386.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    18. Designing a pain management protocol for craniotomy: A narrative review and consideration of promising practices. Surg Neurol Int. 2017; 8:291. Vacas S, Van de Wiele B. PMID: 29285407; PMCID: PMC5735429.
      View in: PubMed   Mentions: 7  
    19. In Response. Anesth Analg. 2017 08; 125(2):695-696. Vacas S, Maze M. PMID: 28661919; PMCID: PMC5654546.
      View in: PubMed   Mentions:    Fields:    
    20. Fragmented Sleep Enhances Postoperative Neuroinflammation but Not Cognitive Dysfunction. Anesth Analg. 2017 01; 124(1):270-276. Vacas S, Degos V, Maze M. PMID: 27755058.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    21. Initiating Mechanisms of Surgery-induced Memory Decline: The Role of HMGB1. J Clin Cell Immunol. 2016 Dec; 7(6). Vacas S, Maze M. PMID: 28674635; PMCID: PMC5493140.
      View in: PubMed   Mentions: 2  
    22. Perioperative cerebrospinal fluid and plasma inflammatory markers after orthopedic surgery. J Neuroinflammation. 2016 08 30; 13(1):211. Hirsch J, Vacas S, Terrando N, Yuan M, Sands LP, Kramer J, Bozic K, Maze MM, Leung JM. PMID: 27577265; PMCID: PMC5006595.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    23. The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor. Anesth Analg. 2016 07; 123(1):206-12. Vacas S, McInrue E, Gropper MA, Maze M, Zak R, Lim E, Leung JM. PMID: 27159066; PMCID: PMC5493322.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. In reply. Anesthesiology. 2014 Dec; 121(6):1353-4. Vacas S, Degos V, Maze M. PMID: 25405302.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    25. High-mobility group box 1 protein initiates postoperative cognitive decline by engaging bone marrow-derived macrophages. Anesthesiology. 2014 May; 120(5):1160-7. Vacas S, Degos V, Tracey KJ, Maze M. PMID: 24162463; PMCID: PMC3999217.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    26. Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: a pharmacokinetic and pharmacodynamic study. Anesthesiology. 2014 May; 120(5):1118-25. Flexman AM, Wong H, Riggs KW, Shih T, Garcia PA, Vacas S, Talke PO. PMID: 24487703.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    27. Bone fracture exacerbates murine ischemic cerebral injury. Anesthesiology. 2013 Jun; 118(6):1362-72. Degos V, Maze M, Vacas S, Hirsch J, Guo Y, Shen F, Jun K, van Rooijen N, Gressens P, Young WL, Su H. PMID: 23438676; PMCID: PMC3987811.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    28. Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome. Anesthesiology. 2013 May; 118(5):1098-105. Feng X, Degos V, Koch LG, Britton SL, Zhu Y, Vacas S, Terrando N, Nelson J, Su X, Maze M. PMID: 23353794; PMCID: PMC5530762.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    29. The neuroinflammatory response of postoperative cognitive decline. Br Med Bull. 2013; 106:161-78. Vacas S, Degos V, Feng X, Maze M. PMID: 23558082; PMCID: PMC4990823.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    30. Sleep and Anesthesia - Common mechanisms of action. Sleep Med Clin. 2013 Mar; 8(1):1-9. Vacas S, Kurien P, Maze M. PMID: 28747855; PMCID: PMC5524381.
      View in: PubMed   Mentions: 6     Fields:    
    31. Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction. Anesthesiology. 2013 Mar; 118(3):527-36. Degos V, Vacas S, Han Z, van Rooijen N, Gressens P, Su H, Young WL, Maze M. PMID: 23426204; PMCID: PMC3779063.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    32. Perioperative cognitive decline in the aging population. Mayo Clin Proc. 2011 Sep; 86(9):885-93. Terrando N, Brzezinski M, Degos V, Eriksson LI, Kramer JH, Leung JM, Miller BL, Seeley WW, Vacas S, Weiner MW, Yaffe K, Young WL, Xie Z, Maze M. PMID: 21878601; PMCID: PMC3257991.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
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