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Tamir Gonen

Title(s)Professor, Physiology
SchoolMedicine
Phone52716
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    Other Positions
    Title(s)Professor, Biological Chemistry


    Collapse Research 
    Collapse Research Activities and Funding
    MEDIC - MicroED Imaging Center at UCLA
    NIH/NIGMS P41GM136508May 1, 2020 - Apr 30, 2025
    Role: Principal Investigator
    Influence of lipids on membrane protein structure and function
    NIH/NIGMS R01GM079233May 1, 2007 - Dec 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wolff AM, Young ID, Sierra RG, Brewster AS, Martynowycz MW, Nango E, Sugahara M, Nakane T, Ito K, Aquila A, Bhowmick A, Biel JT, Carbajo S, Cohen AE, Cortez S, Gonzalez A, Hino T, Im D, Koralek JD, Kubo M, Lazarou TS, Nomura T, Owada S, Samelson AJ, Tanaka T, Tanaka R, Thompson EM, van den Bedem H, Woldeyes RA, Yumoto F, Zhao W, Tono K, Boutet S, Iwata S, Gonen T, Sauter NK, Fraser JS, Thompson MC. Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals. IUCrJ. 2020 Mar 01; 7(Pt 2):306-323. PMID: 32148858.
      View in: PubMed
    2. Martynowycz MW, Hattne J, Gonen T. Experimental Phasing of MicroED Data Using Radiation Damage. Structure. 2020 Feb 04. PMID: 32023481.
      View in: PubMed
    3. Dick M, Sarai NS, Martynowycz MW, Gonen T, Arnold FH. Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation. J Am Chem Soc. 2019 Dec 18; 141(50):19817-19822. PMID: 31747522.
      View in: PubMed
    4. Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. Structure-based inhibitors of amyloid beta core suggest a common interface with tau. Elife. 2019 10 15; 8. PMID: 31612856.
      View in: PubMed
    5. Hattne J, Martynowycz MW, Penczek PA, Gonen T. MicroED with the Falcon III direct electron detector. IUCrJ. 2019 Sep 01; 6(Pt 5):921-926. PMID: 31576224.
      View in: PubMed
    6. Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T. Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED. Structure. 2019 10 01; 27(10):1594-1600.e2. PMID: 31422911.
      View in: PubMed
    7. Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG. Structure of amyloid-ß (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun. 2019 07 26; 10(1):3357. PMID: 31350392.
      View in: PubMed
    8. Ting CP, Funk MA, Halaby SL, Zhang Z, Gonen T, van der Donk WA. Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products. Science. 2019 07 19; 365(6450):280-284. PMID: 31320540.
      View in: PubMed
    9. Nannenga BL, Gonen T. The cryo-EM method microcrystal electron diffraction (MicroED). Nat Methods. 2019 05; 16(5):369-379. PMID: 31040436.
      View in: PubMed
    10. de la Cruz MJ, Martynowycz MW, Hattne J, Gonen T. MicroED data collection with SerialEM. Ultramicroscopy. 2019 06; 201:77-80. PMID: 30986656.
      View in: PubMed
    11. Zee CT, Glynn C, Gallagher-Jones M, Miao J, Santiago CG, Cascio D, Gonen T, Sawaya MR, Rodriguez JA. Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ. IUCrJ. 2019 Mar 01; 6(Pt 2):197-205. PMID: 30867917.
      View in: PubMed
    12. Ma J, Lei HT, Reyes FE, Sanchez-Martinez S, Sarhan MF, Hattne J, Gonen T. Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2086-2090. PMID: 30659158.
      View in: PubMed
    13. Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T. Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size. Structure. 2019 03 05; 27(3):545-548.e2. PMID: 30661853.
      View in: PubMed
    14. Purdy MD, Shi D, Chrustowicz J, Hattne J, Gonen T, Yeager M. MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):13258-13263. PMID: 30530702.
      View in: PubMed
    15. Jones CG, Martynowycz MW, Hattne J, Fulton TJ, Stoltz BM, Rodriguez JA, Nelson HM, Gonen T. The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination. ACS Cent Sci. 2018 Nov 28; 4(11):1587-1592. PMID: 30555912.
      View in: PubMed
    16. Nannenga BL, Gonen T. Correction: MicroED: a versatile cryoEM method for structure determination. Emerg Top Life Sci. 2018 Sep 28; 2(2):331. PMID: 32412608.
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    17. Lei HT, Ma J, Sanchez Martinez S, Gonen T. Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state. Nat Struct Mol Biol. 2018 06; 25(6):522-527. PMID: 29872228.
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    18. Liu S, Gonen T. MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter. Commun Biol. 2018; 1:38. PMID: 30167468.
      View in: PubMed
    19. Hattne J, Shi D, Glynn C, Zee CT, Gallagher-Jones M, Martynowycz MW, Rodriguez JA, Gonen T. Analysis of Global and Site-Specific Radiation Damage in Cryo-EM. Structure. 2018 05 01; 26(5):759-766.e4. PMID: 29706530.
      View in: PubMed
    20. Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat Struct Mol Biol. 2018 04; 25(4):311-319. PMID: 29531287.
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    21. Liu Y, Gonen S, Gonen T, Yeates TO. Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system. Proc Natl Acad Sci U S A. 2018 03 27; 115(13):3362-3367. PMID: 29507202.
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    22. Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS. Atomic structures of low-complexity protein segments reveal kinked ß sheets that assemble networks. Science. 2018 02 09; 359(6376):698-701. PMID: 29439243.
      View in: PubMed
    23. Nannenga BL, Gonen T. MicroED: a versatile cryoEM method for structure determination. Emerg Top Life Sci. 2018 Apr 20; 2(1):1-8. PMID: 30167465.
      View in: PubMed
    24. Martynowycz MW, Gonen T. From electron crystallography of 2D crystals to MicroED of 3D crystals. Curr Opin Colloid Interface Sci. 2018 Mar; 34:9-16. PMID: 30166936.
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    25. Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA. Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp. Nat Struct Mol Biol. 2018 02; 25(2):131-134. PMID: 29335561.
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    26. Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. Common fibrillar spines of amyloid-ß and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J Biol Chem. 2018 02 23; 293(8):2888-2902. PMID: 29282295.
      View in: PubMed
    27. Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. Structure-based inhibitors of tau aggregation. Nat Chem. 2018 02; 10(2):170-176. PMID: 29359764.
      View in: PubMed
    28. Vergara S, Lukes DA, Martynowycz MW, Santiago U, Plascencia-Villa G, Weiss SC, de la Cruz MJ, Black DM, Alvarez MM, López-Lozano X, Barnes CO, Lin G, Weissker HC, Whetten RL, Gonen T, Yacaman MJ, Calero G. MicroED Structure of Au146(p-MBA)57 at Subatomic Resolution Reveals a Twinned FCC Cluster. J Phys Chem Lett. 2017 Nov 16; 8(22):5523-5530. PMID: 29072840.
      View in: PubMed
    29. Wright ZVF, McCarthy S, Dickman R, Reyes FE, Sanchez-Martinez S, Cryar A, Kilford I, Hall A, Takle AK, Topf M, Gonen T, Thalassinos K, Tabor AB. The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Nav1.7. J Am Chem Soc. 2017 09 20; 139(37):13063-13075. PMID: 28880078.
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    30. Rodriguez JA, Eisenberg DS, Gonen T. Taking the measure of MicroED. Curr Opin Struct Biol. 2017 10; 46:79-86. PMID: 28648726.
      View in: PubMed
    31. de la Cruz MJ, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SK, Hinck CS, Hinck AP, Calero G, Eisenberg D, Gonen T. Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat Methods. 2017 Feb 13; 14(4):399-402. PMID: 28192420.
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    32. Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S, Griner S, Jiang L, Glabe CG, Westermark GT, Gonen T, Eisenberg DS. Atomic structures of fibrillar segments of hIAPP suggest tightly mated ß-sheets are important for cytotoxicity. Elife. 2017 01 03; 6. PMID: 28045370.
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    33. Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Corrigendum: Design of a hyperstable 60-subunit protein icosahedron. Nature. 2016 12 01; 540(7631):150. PMID: 27760110.
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    34. Nannenga BL, Gonen T. MicroED opens a new era for biological structure determination. Curr Opin Struct Biol. 2016 10; 40:128-135. PMID: 27701014.
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    35. Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):11232-11236. PMID: 27647903.
      View in: PubMed
    36. Liu S, Hattne J, Reyes FE, Sanchez-Martinez S, Jason de la Cruz M, Shi D, Gonen T. Atomic resolution structure determination by the cryo-EM method MicroED. Protein Sci. 2017 01; 26(1):8-15. PMID: 27452773.
      View in: PubMed
    37. Bale JB, Gonen S, Liu Y, Sheffler W, Ellis D, Thomas C, Cascio D, Yeates TO, Gonen T, King NP, Baker D. Accurate design of megadalton-scale two-component icosahedral protein complexes. Science. 2016 Jul 22; 353(6297):389-94. PMID: 27463675.
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    38. Rodriguez JA, Gonen T. High-Resolution Macromolecular Structure Determination by MicroED, a cryo-EM Method. Methods Enzymol. 2016; 579:369-92. PMID: 27572734.
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    39. Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Design of a hyperstable 60-subunit protein dodecahedron. [corrected]. Nature. 2016 07 07; 535(7610):136-9. PMID: 27309817.
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    40. Hattne J, Shi D, de la Cruz MJ, Reyes FE, Gonen T. Modeling truncated pixel values of faint reflections in MicroED images. J Appl Crystallogr. 2016 Jun 01; 49(Pt 3):1029-1034. PMID: 27275145.
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    41. Shi D, Nannenga BL, de la Cruz MJ, Liu J, Sawtelle S, Calero G, Reyes FE, Hattne J, Gonen T. The collection of MicroED data for macromolecular crystallography. Nat Protoc. 2016 May; 11(5):895-904. PMID: 27077331.
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    42. Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. Data publication with the structural biology data grid supports live analysis. Nat Commun. 2016 Mar 07; 7:10882. PMID: 26947396.
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    43. Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS. Structure of the toxic core of a-synuclein from invisible crystals. Nature. 2015 Sep 24; 525(7570):486-90. PMID: 26352473.
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    44. Bale JB, Park RU, Liu Y, Gonen S, Gonen T, Cascio D, King NP, Yeates TO, Baker D. Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression. Protein Sci. 2015 Oct; 24(10):1695-701. PMID: 26174163.
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    45. Hattne J, Reyes FE, Nannenga BL, Shi D, de la Cruz MJ, Leslie AG, Gonen T. MicroED data collection and processing. Acta Crystallogr A Found Adv. 2015 Jul; 71(Pt 4):353-60. PMID: 26131894.
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    46. Gonen S, DiMaio F, Gonen T, Baker D. Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces. Science. 2015 Jun 19; 348(6241):1365-8. PMID: 26089516.
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    47. Huang PS, Oberdorfer G, Xu C, Pei XY, Nannenga BL, Rogers JM, DiMaio F, Gonen T, Luisi B, Baker D. High thermodynamic stability of parametrically designed helical bundles. Science. 2014 Oct 24; 346(6208):481-485. PMID: 25342806.
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    48. Nannenga BL, Shi D, Hattne J, Reyes FE, Gonen T. Structure of catalase determined by MicroED. Elife. 2014 Oct 10; 3:e03600. PMID: 25303172.
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    49. Gonen T, Waksman G. Editorial overview: Membranes: recent methods in the study of membrane protein structure. Curr Opin Struct Biol. 2014 Aug; 27:iv-v. PMID: 25242735.
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    50. Wisedchaisri G, Park MS, Iadanza MG, Zheng H, Gonen T. Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE. Nat Commun. 2014 Aug 04; 5:4521. PMID: 25088546.
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    51. Nannenga BL, Shi D, Leslie AGW, Gonen T. High-resolution structure determination by continuous-rotation data collection in MicroED. Nat Methods. 2014 Sep; 11(9):927-930. PMID: 25086503.
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    52. Russell AB, Wexler AG, Harding BN, Whitney JC, Bohn AJ, Goo YA, Tran BQ, Barry NA, Zheng H, Peterson SB, Chou S, Gonen T, Goodlett DR, Goodman AL, Mougous JD. A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism. Cell Host Microbe. 2014 Aug 13; 16(2):227-236. PMID: 25070807.
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    53. Iadanza MG, Gonen T. A suite of software for processing MicroED data of extremely small protein crystals. J Appl Crystallogr. 2014 Jun 01; 47(Pt 3):1140-1145. PMID: 24904248.
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    54. King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D. Accurate design of co-assembling multi-component protein nanomaterials. Nature. 2014 Jun 05; 510(7503):103-8. PMID: 24870237.
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    55. Nannenga BL, Gonen T. Protein structure determination by MicroED. Curr Opin Struct Biol. 2014 Aug; 27:24-31. PMID: 24709395.
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    56. Anderson TM, Clay MC, Cioffi AG, Diaz KA, Hisao GS, Tuttle MD, Nieuwkoop AJ, Comellas G, Maryum N, Wang S, Uno BE, Wildeman EL, Gonen T, Rienstra CM, Burke MD. Amphotericin forms an extramembranous and fungicidal sterol sponge. Nat Chem Biol. 2014 May; 10(5):400-6. PMID: 24681535.
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    57. Shi D, Nannenga BL, Iadanza MG, Gonen T. Three-dimensional electron crystallography of protein microcrystals. Elife. 2013 Nov 19; 2:e01345. PMID: 24252878.
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    58. Smith FD, Reichow SL, Esseltine JL, Shi D, Langeberg LK, Scott JD, Gonen T. Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife. 2013 Nov 05; 2:e01319. PMID: 24192038.
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    59. Gold MG, Gonen T, Scott JD. Local cAMP signaling in disease at a glance. J Cell Sci. 2013 Oct 15; 126(Pt 20):4537-43. PMID: 24124191.
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    60. Silverman JM, Agnello DM, Zheng H, Andrews BT, Li M, Catalano CE, Gonen T, Mougous JD. Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates. Mol Cell. 2013 Sep 12; 51(5):584-93. PMID: 23954347.
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    61. Reichow SL, Clemens DM, Freites JA, Németh-Cahalan KL, Heyden M, Tobias DJ, Hall JE, Gonen T. Allosteric mechanism of water-channel gating by Ca2+-calmodulin. Nat Struct Mol Biol. 2013 Sep; 20(9):1085-92. PMID: 23893133.
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    62. Zheng H, Wisedchaisri G, Gonen T. Crystal structure of a nitrate/nitrite exchanger. Nature. 2013 May 30; 497(7451):647-51. PMID: 23665960.
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    63. Shi L, Zheng H, Zheng H, Borkowski BA, Shi D, Gonen T, Jiang QX. Retraction for Shi et al., "Voltage sensor ring in a native structure of a membrane-embedded potassium channel". Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):7097. PMID: 23530252.
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    64. Shi L, Zheng H, Zheng H, Borkowski BA, Shi D, Gonen T, Jiang QX. Voltage sensor ring in a native structure of a membrane-embedded potassium channel. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3369-74. PMID: 23401554.
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    65. Nannenga BL, Iadanza MG, Vollmar BS, Gonen T. Overview of electron crystallography of membrane proteins: crystallization and screening strategies using negative stain electron microscopy. Curr Protoc Protein Sci. 2013; Chapter 17:Unit17.15. PMID: 23546618.
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    66. Gonen T. The collection of high-resolution electron diffraction data. Methods Mol Biol. 2013; 955:153-69. PMID: 23132060.
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    67. Stokes DL, Ubarretxena-Belandia I, Gonen T, Engel A. High-throughput methods for electron crystallography. Methods Mol Biol. 2013; 955:273-96. PMID: 23132066.
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    68. Wisedchaisri G, Gonen T. Phasing electron diffraction data by molecular replacement: strategy for structure determination and refinement. Methods Mol Biol. 2013; 955:243-72. PMID: 23132065.
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    69. Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nat Struct Mol Biol. 2013 Feb; 20(2):150-8. PMID: 23262488.
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    70. Umbreit NT, Gestaut DR, Tien JF, Vollmar BS, Gonen T, Asbury CL, Davis TN. The Ndc80 kinetochore complex directly modulates microtubule dynamics. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16113-8. PMID: 22908300.
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    71. Gonen S, Akiyoshi B, Iadanza MG, Shi D, Duggan N, Biggins S, Gonen T. The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nat Struct Mol Biol. 2012 Sep; 19(9):925-9. PMID: 22885327.
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    72. Gonen T, Waksman G. Recent progress in membrane protein structures and investigation methods. Curr Opin Struct Biol. 2012 Aug; 22(4):467-8. PMID: 22819667.
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    73. King NP, Sheffler W, Sawaya MR, Vollmar BS, Sumida JP, André I, Gonen T, Yeates TO, Baker D. Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science. 2012 Jun 01; 336(6085):1171-4. PMID: 22654060.
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    74. Jiang QX, Gonen T. The influence of lipids on voltage-gated ion channels. Curr Opin Struct Biol. 2012 Aug; 22(4):529-36. PMID: 22483432.
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    75. Lo SY, Brett CL, Plemel RL, Vignali M, Fields S, Gonen T, Merz AJ. Intrinsic tethering activity of endosomal Rab proteins. Nat Struct Mol Biol. 2011 Dec 11; 19(1):40-7. PMID: 22157956.
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    76. Gold MG, Reichow SL, O'Neill SE, Weisbrod CR, Langeberg LK, Bruce JE, Gonen T, Scott JD. AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency. EMBO Mol Med. 2012 Jan; 4(1):15-26. PMID: 22095752.
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    77. Wisedchaisri G, Reichow SL, Gonen T. Advances in structural and functional analysis of membrane proteins by electron crystallography. Structure. 2011 Oct 12; 19(10):1381-93. PMID: 22000511.
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    78. Wisedchaisri G, Gonen T. Fragment-based phase extension for three-dimensional structure determination of membrane proteins by electron crystallography. Structure. 2011 Jul 13; 19(7):976-87. PMID: 21742264.
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    79. Budzinski KL, Sgro AE, Fujimoto BS, Gadd JC, Shuart NG, Gonen T, Bajjaleih SM, Chiu DT. Synaptosomes as a platform for loading nanoparticles into synaptic vesicles. ACS Chem Neurosci. 2011 May 18; 2(5):236-241. PMID: 21666849.
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    80. Korotkov KV, Gonen T, Hol WG. Secretins: dynamic channels for protein transport across membranes. Trends Biochem Sci. 2011 Aug; 36(8):433-43. PMID: 21565514.
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    81. Reichow SL, Korotkov KV, Gonen M, Sun J, Delarosa JR, Hol WG, Gonen T. The binding of cholera toxin to the periplasmic vestibule of the type II secretion channel. Channels (Austin). 2011 May-Jun; 5(3):215-8. PMID: 21406971.
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    82. Jehle S, Vollmar BS, Bardiaux B, Dove KK, Rajagopal P, Gonen T, Oschkinat H, Klevit RE. N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6409-14. PMID: 21464278.
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    83. Akiyoshi B, Sarangapani KK, Powers AF, Nelson CR, Reichow SL, Arellano-Santoyo H, Gonen T, Ranish JA, Asbury CL, Biggins S. Tension directly stabilizes reconstituted kinetochore-microtubule attachments. Nature. 2010 Nov 25; 468(7323):576-9. PMID: 21107429.
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    84. Wisedchaisri G, Dranow DM, Lie TJ, Bonanno JB, Patskovsky Y, Ozyurt SA, Sauder JM, Almo SC, Wasserman SR, Burley SK, Leigh JA, Gonen T. Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. Structure. 2010 Nov 10; 18(11):1512-21. PMID: 21070950.
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    85. Hall Sedlak R, Hnilova M, Gachelet E, Przybyla L, Dranow D, Gonen T, Sarikaya M, Tamerler C, Traxler B. An engineered DNA-binding protein self-assembles metallic nanostructures. Chembiochem. 2010 Oct 18; 11(15):2108-12. PMID: 20827792.
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    86. Reichow SL, Korotkov KV, Hol WG, Gonen T. Structure of the cholera toxin secretion channel in its closed state. Nat Struct Mol Biol. 2010 Oct; 17(10):1226-32. PMID: 20852644.
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    87. Sanowar S, Singh P, Pfuetzner RA, André I, Zheng H, Spreter T, Strynadka NC, Gonen T, Baker D, Goodlett DR, Miller SI. Interactions of the transmembrane polymeric rings of the Salmonella enterica serovar Typhimurium type III secretion system. mBio. 2010 Aug 03; 1(3). PMID: 20824104.
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    88. Tien JF, Umbreit NT, Gestaut DR, Franck AD, Cooper J, Wordeman L, Gonen T, Asbury CL, Davis TN. Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B. J Cell Biol. 2010 May 17; 189(4):713-23. PMID: 20479468.
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    89. Zheng H, Taraska J, Merz AJ, Gonen T. The prototypical H+/galactose symporter GalP assembles into functional trimers. J Mol Biol. 2010 Feb 26; 396(3):593-601. PMID: 20006622.
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    90. Reichow SL, Gonen T. Lipid-protein interactions probed by electron crystallography. Curr Opin Struct Biol. 2009 Oct; 19(5):560-5. PMID: 19679462.
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    91. Reichow SL, Gonen T. Noncanonical binding of calmodulin to aquaporin-0: implications for channel regulation. Structure. 2008 Sep 10; 16(9):1389-98. PMID: 18786401.
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