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Tomas Ganz

Title(s)Professor, Medicine
SchoolMedicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
Phone3108256112
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    Other Positions
    Title(s)Professor, Pathology and Laboratory Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    Bioiron 2013: From basic science to medicine
    NIH/NIDDK R13DK098971Apr 1, 2013 - Mar 31, 2014
    Role: Principal Investigator
    Bioiron 2011: From basic science to medicine
    NIH/NIDDK R13DK092102May 1, 2011 - Apr 30, 2012
    Role: Principal Investigator
    Activin signaling in normal and disordered erythropoiesis
    NIH/NIDDK R01DK090554Sep 30, 2010 - Jul 31, 2015
    Role: Co-Principal Investigator
    THE ROLE OF INFLAMMATION IN ANEMIA OF THE ELDERLY
    NIH/NHLBI R01HL091531Jun 15, 2007 - May 31, 2011
    Role: Principal Investigator
    The role of hemojuvelin in the regulation of iron metabolism
    NIH/NIDDK R21DK073226Feb 15, 2006 - Jan 31, 2008
    Role: Principal Investigator
    The role of erythroferrone in iron homeostasis and in iron-loading anemias
    NIH/NIDDK R01DK065029Jul 1, 2003 - Jun 30, 2018
    Role: Principal Investigator
    UCLA Pulmonary and Critical Care Medicine Training Program
    NIH/NHLBI T32HL072752Jul 1, 2003 - Jun 30, 2014
    Role: Co-Principal Investigator
    NASAL CARRIAGE OF STAPHYLOCOCCUS AUREUS
    NIH/NIAID R21AI048167Sep 30, 2000 - Sep 29, 2003
    Role: Principal Investigator
    INNATE HOST DEFENSE IN THE HUMAN VAGINA
    NIH/NIAID R01AI046514Sep 15, 2000 - May 31, 2005
    Role: Principal Investigator
    CONFERENCE ANTIMICROBIAL PEPTIDES OF HIGHER EUKARYOTES
    NIH/NIAID R13AI040440Mar 1, 1997 - Feb 28, 1998
    Role: Principal Investigator
    BETA-DEFENSINS IN THE FEMALE GENITAL TRACT AND KIDNEYS
    NIH/NIAID R01AI040248Aug 1, 1996 - Jul 31, 2001
    Role: Principal Investigator
    IMMUNOPOTENTIATION BY TRANSGENIC ANTIMICROBIAL PEPTIDES
    NIH/NIAID R01AI038567Sep 30, 1995 - Jul 31, 1998
    Role: Principal Investigator
    Human Defensins in Phagocytes and Epithelia
    NIH/NHLBI R01HL046809Jan 1, 1993 - Jun 30, 2005
    Role: Principal Investigator
    CATIONIC PEPTIDES AND THE LUNG
    NIH/NHLBI R01HL035640Apr 1, 1988 - Nov 30, 1990
    Role: Principal Investigator
    MICROBICIDAL MECHANISMS AGAINST PNEUMOCYSTIS CARINII
    NIH/NIAID R01AI021931Sep 30, 1984 - Aug 31, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Maternal Hepcidin Determines Embryo Iron Homeostasis. Blood. 2020 Jun 25. Sangkhae V, Fisher AL, Chua KJ, Ruchala P, Ganz T, Nemeth E. PMID: 32584957.
      View in: PubMed   Mentions:    Fields:    
    2. Iron overload causes a mild and transient increase in acute lung injury. Physiol Rep. 2020 Jun; 8(12):e14470. Zhang V, Ganz T, Nemeth E, Kim A. PMID: 32596989.
      View in: PubMed   Mentions:    Fields:    
    3. The Authors Reply. Kidney Int Rep. 2020 Jul; 5(7):1119-1120. Sharma S, Hanudel MR, Ix JH, Salusky IB, Ganz T, Nguyen KL. PMID: 32647775.
      View in: PubMed   Mentions:
    4. Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors. J Appl Lab Med. 2020 Apr 24. Gutschow P, Han H, Olbina G, Westerman K, Nemeth E, Ganz T, Copeland K, Westerman M, Ostland V. PMID: 32674118.
      View in: PubMed   Mentions:    Fields:    
    5. Author Correction: Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2020 Apr; 52(4):463. Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. PMID: 32107478.
      View in: PubMed   Mentions:    Fields:    
    6. Iron Administration, Infection, and Anemia Management in CKD: Untangling the Effects of Intravenous Iron Therapy on Immunity and Infection Risk. Kidney Med. 2020 May-Jun; 2(3):341-353. Ganz T, Aronoff GR, Gaillard CAJM, Goodnough LT, Macdougall IC, Mayer G, Porto G, Winkelmayer WC, Wish JB. PMID: 32734254.
      View in: PubMed   Mentions:
    7. Fetal and amniotic fluid iron homeostasis in healthy and complicated murine, macaque, and human pregnancy. JCI Insight. 2020 02 27; 5(4). Fisher AL, Sangkhae V, Presicce P, Chougnet CA, Jobe AH, Kallapur SG, Tabbah S, Buhimschi CS, Buhimschi IA, Ganz T, Nemeth E. PMID: 31990688.
      View in: PubMed   Mentions:    Fields:    
    8. Drugging erythroferrone to treat anemias. Blood. 2020 Feb 20; 135(8):516-518. Ganz T. PMID: 32078688.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. Effects of maternal iron status on placental and fetal iron homeostasis. J Clin Invest. 2020 Feb 03; 130(2):625-640. Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, Lelic M, Ganz T, Nemeth E. PMID: 31661462.
      View in: PubMed   Mentions:    Fields:    
    10. Effects of erythropoietin on fibroblast growth factor 23 in mice and humans. Nephrol Dial Transplant. 2019 12 01; 34(12):2057-2065. Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, Gaillard CAJM, Ganz T. PMID: 30007314.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    11. Anemia of Inflammation. N Engl J Med. 2019 Sep 19; 381(12):1148-1157. Ganz T. PMID: 31532961.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Elevated Fibroblast Growth Factor 23 Levels Are Associated With Greater Diastolic Dysfunction in ESRD. Kidney Int Rep. 2019 Dec; 4(12):1748-1751. Sharma S, Hanudel MR, Ix JH, Salusky IB, Ganz T, Nguyen KL. PMID: 31844812.
      View in: PubMed   Mentions:
    13. A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome. Sci Transl Med. 2019 07 10; 11(500). Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M. PMID: 31292266.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    14. Novel Oral Iron Therapies for Iron Deficiency Anemia in Chronic Kidney Disease. Adv Chronic Kidney Dis. 2019 07; 26(4):272-291. Pergola PE, Fishbane S, Ganz T. PMID: 31477258.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The Discovery of the Iron-Regulatory Hormone Hepcidin. Clin Chem. 2019 10; 65(10):1330-1331. Ganz T. PMID: 31235538.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    16. Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). Drugs. 2019 Jun; 79(9):957-968. Ganz T, Bino A, Salusky IB. PMID: 31134521.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. William Ganz and His Legacy. Ann Intern Med. 2019 05 21; 170(10):734-735. Ganz T, Ganz P. PMID: 31108522.
      View in: PubMed   Mentions:    Fields:    
    18. Iron Metabolism in Chronic Kidney Disease Patients. Contrib Nephrol. 2019; 198:103-111. Honda H, Hosaka N, Ganz T, Shibata T. PMID: 30991401.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and ß-thalassemia. Haematologica. 2019 09; 104(9):1768-1781. Liu J, Liu W, Liu Y, Miao Y, Guo Y, Song H, Wang F, Zhou H, Ganz T, Yan B, Liu S. PMID: 30792208.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    20. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiat Res. 2019 04; 191(4):323-334. Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. PMID: 30730284.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsPHPublic Health
    21. Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3161-3170. Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X. PMID: 30718392.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    22. Iron homeostasis in pregnancy and spontaneous abortion. Am J Hematol. 2019 02; 94(2):184-188. Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E. PMID: 30394565.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Erythrocytes and erythroblasts give up iron. Blood. 2018 11 08; 132(19):2004-2005. Ganz T. PMID: 30409893.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    24. Anemia of inflammation. Blood. 2019 01 03; 133(1):40-50. Weiss G, Ganz T, Goodnough LT. PMID: 30401705.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    25. Erythropoietin and iron-a conflicted alliance? Kidney Int. 2018 11; 94(5):851-853. Ganz T. PMID: 30348300.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    26. Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer. Am J Physiol Endocrinol Metab. 2018 12 01; 315(6):E1185-E1193. Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S. PMID: 30325657.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Physiol Rep. 2018 09; 6(19):e13890. Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T. PMID: 30315639.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    28. Calcium is an essential cofactor for metal efflux by the ferroportin transporter family. Nat Commun. 2018 08 06; 9(1):3075. Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M. PMID: 30082682.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Erythropoietic regulators of iron metabolism. Free Radic Biol Med. 2019 03; 133:69-74. Ganz T. PMID: 29981834.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    30. Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients. Infect Immun. 2018 07; 86(7). Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y. PMID: 29735522.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    31. Iron storage disease (hemochromatosis) and hepcidin response to iron load in two species of pteropodid fruit bats relative to the common vampire bat. J Comp Physiol B. 2018 07; 188(4):683-694. Stasiak IM, Smith DA, Ganz T, Crawshaw GJ, Hammermueller JD, Bienzle D, Lillie BN. PMID: 29594459.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    32. Erythroferrone: An Erythroid Regulator of Hepcidin and Iron Metabolism. Hemasphere. 2018 Mar-Apr; 2(2):e35. Coffey R, Ganz T. PMID: 31723763.
      View in: PubMed   Mentions:
    33. Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype. Hepatol Int. 2018 Mar; 12(2):83-86. Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, Nemeth E, Nielsen P, Pineau B, Piperno A, Porto G, Prince D, Ryan J, Sanchez M, Santos P, Swinkels D, Teixeira E, Toska K, Vanclooster A, White D. PMID: 29589198.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood Cells Mol Dis. 2018 07; 71:63-66. Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM. PMID: 29599085.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell? Am J Nephrol. 2018; 47(2):72-83. Wish JB, Aronoff GR, Bacon BR, Brugnara C, Eckardt KU, Ganz T, Macdougall IC, Núñez J, Perahia AJ, Wood JC. PMID: 29439253.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease. Haematologica. 2018 04; 103(4):e141-e142. Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E. PMID: 29419424.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    37. Comment on "Serum Hepcidin and Soluble Transferrin Receptor in the Assessment of Iron Metabolism in Children on a Vegetarian Diet". Biol Trace Elem Res. 2018 09; 185(1):252-254. Rzymski P, Ganz T. PMID: 29322429.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Correction to: Iron and infection. Int J Hematol. 2018 01; 107(1):122. Ganz T. PMID: 29197980.
      View in: PubMed   Mentions: 1     Fields:    
    39. Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin. Blood. 2018 02 22; 131(8):899-910. Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E. PMID: 29237594.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    40. Iron-related markers are associated with infection after liver transplantation. Liver Transpl. 2017 12; 23(12):1541-1552. Chow JKL, Ganz T, Ruthazer R, Simpson MA, Pomfret EA, Gordon FD, Westerman ME, Snydman DR. PMID: 28703464.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Iron and infection. Int J Hematol. 2018 Jan; 107(1):7-15. Ganz T. PMID: 29147843.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    42. In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively than Iron and Erythropoietin Treatment. Shock. 2017 10; 48(4):490-497. Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A. PMID: 28452907.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    43. Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis. Antioxid Redox Signal. 2018 Jan 01; 28(1):1-14. Matte A, De Falco L, Federti E, Cozzi A, Iolascon A, Levi S, Mohandas N, Zamo A, Bruno M, Lebouef C, Janin A, Siciliano A, Ganz T, Federico G, Carlomagno F, Mueller S, Silva I, Carbone C, Melisi D, Kim DW, Choi SY, De Franceschi L. PMID: 28793778.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    44. Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow. Haematologica. 2017 11; 102(11):e427-e430. Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE. PMID: 28818868.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    45. Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 01; 313(5):G511-G523. McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. PMID: 28798083.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    46. Immunoassay for human serum erythroferrone. Blood. 2017 09 07; 130(10):1243-1246. Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E. PMID: 28739636.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    47. Iron homeostasis: An anthropocentric perspective. J Biol Chem. 2017 08 04; 292(31):12727-12734. Coffey R, Ganz T. PMID: 28615456.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    48. Does Pathological Iron Overload Impair the Function of Human Lungs? EBioMedicine. 2017 06; 20:13-14. Ganz T. PMID: 28545989.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron. Blood. 2017 07 20; 130(3):245-257. Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E. PMID: 28465342.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    50. Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia. JCI Insight. 2017 03 23; 2(6):e92002. Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B. PMID: 28352667.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    51. Mice lacking liver-specific ß-catenin develop steatohepatitis and fibrosis after iron overload. J Hepatol. 2017 08; 67(2):360-369. Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. PMID: 28341391.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    52. Erythroferrone and matriptase-2 independently regulate hepcidin expression. Am J Hematol. 2017 05; 92(5):E61-E63. Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L. PMID: 28187515.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    53. Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model. Haematologica. 2017 03; 102(3):e85-e88. Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J. PMID: 27884972.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    54. Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice. Am J Physiol Renal Physiol. 2016 12 01; 311(6):F1369-F1377. Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB. PMID: 27733366.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    55. Macrophages and Iron Metabolism. Microbiol Spectr. 2016 10; 4(5). Ganz T. PMID: 27763254.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    56. Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia. Haematologica. 2017 01; 102(1):60-68. Latour C, Wlodarczyk MF, Jung G, Gineste A, Blanchard N, Ganz T, Roth MP, Coppin H, Kautz L. PMID: 27658439.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    57. Minihepcidin peptides as disease modifiers in mice affected by ß-thalassemia and polycythemia vera. Blood. 2016 07 14; 128(2):265-76. Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S. PMID: 27154187.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    58. Iron Balance and the Role of Hepcidin in Chronic Kidney Disease. Semin Nephrol. 2016 03; 36(2):87-93. Ganz T, Nemeth E. PMID: 27236128.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    59. Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics. Biochim Biophys Acta. 2016 Apr; 1863(4):727-48. Kalinowski DS, Stefani C, Toyokuni S, Ganz T, Anderson GJ, Subramaniam NV, Trinder D, Olynyk JK, Chua A, Jansson PJ, Sahni S, Lane DJ, Merlot AM, Kovacevic Z, Huang ML, Lee CS, Richardson DR. PMID: 26844773.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    60. Hepcidin. Rinsho Ketsueki. 2016; 57(10):1913-1917. Ganz T. PMID: 27725588.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    61. Ironing out Ferroportin. Cell Metab. 2015 Nov 03; 22(5):777-87. Drakesmith H, Nemeth E, Ganz T. PMID: 26437604.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    62. Isocitrate treatment of acute anemia of inflammation in a mouse model. Blood Cells Mol Dis. 2016 Jan; 56(1):31-6. Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T. PMID: 26603720.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    63. Hepcidin and Host Defense against Infectious Diseases. PLoS Pathog. 2015 Aug; 11(8):e1004998. Michels K, Nemeth E, Ganz T, Mehrad B. PMID: 26291319.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    64. Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of ß-thalassemia. Blood. 2015 Oct 22; 126(17):2031-7. Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T. PMID: 26276665.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    65. Iron homeostasis in host defence and inflammation. Nat Rev Immunol. 2015 Aug; 15(8):500-10. Ganz T, Nemeth E. PMID: 26160612.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    66. Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver. Exp Hematol. 2015 Jun; 43(6):469-78.e6. Keel SB, Doty R, Liu L, Nemeth E, Cherian S, Ganz T, Abkowitz JL. PMID: 25782630.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    67. Small cyclic agonists of iron regulatory hormone hepcidin. Bioorg Med Chem Lett. 2015 Nov 01; 25(21):4961-4969. Chua K, Fung E, Micewicz ED, Ganz T, Nemeth E, Ruchala P. PMID: 25813158.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    68. Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus. Cell Host Microbe. 2015 Jan 14; 17(1):47-57. Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. PMID: 25590758.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    69. Thiol-derivatized minihepcidins retain biological activity. Bioorg Med Chem Lett. 2015 Feb 15; 25(4):763-6. Fung E, Chua K, Ganz T, Nemeth E, Ruchala P. PMID: 25599838.
      View in: PubMed   Mentions: 4     Fields:    
    70. Hepcidin and the global burden of iron deficiency. Clin Chem. 2015 Apr; 61(4):577-8. Ganz T. PMID: 25492087.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    71. A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis. Haematologica. 2015 Feb; 100(2):167-77. Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M. PMID: 25425686.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    72. The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study. Haematologica. 2015 Jan; 100(1):124-32. Macciò A, Madeddu C, Gramignano G, Mulas C, Tanca L, Cherchi MC, Floris C, Omoto I, Barracca A, Ganz T. PMID: 25239265.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    73. Erythroferrone contributes to recovery from anemia of inflammation. Blood. 2014 Oct 16; 124(16):2569-74. Kautz L, Jung G, Nemeth E, Ganz T. PMID: 25193872.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    74. Disordered hepcidin-ferroportin signaling promotes breast cancer growth. Cell Signal. 2014 Nov; 26(11):2539-50. Zhang S, Chen Y, Guo W, Yuan L, Zhang D, Xu Y, Nemeth E, Ganz T, Liu S. PMID: 25093806.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    75. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014 Jul; 46(7):678-84. Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. PMID: 24880340.
      View in: PubMed   Mentions: 198     Fields:    Translation:Animals
    76. Anemia of inflammation. Hematol Oncol Clin North Am. 2014 Aug; 28(4):671-81, vi. Nemeth E, Ganz T. PMID: 25064707.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    77. Mouse models of anemia of cancer. PLoS One. 2014; 9(3):e93283. Kim A, Rivera S, Shprung D, Limbrick D, Gabayan V, Nemeth E, Ganz T. PMID: 24681760.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    78. A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Blood. 2014 Feb 20; 123(8):1129-36. Kim A, Fung E, Parikh SG, Valore EV, Gabayan V, Nemeth E, Ganz T. PMID: 24357728.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    79. Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin. Hepatology. 2014 Feb; 59(2):683-94. Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP. PMID: 23907767.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    80. Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Rep. 2013 Dec 12; 5(5):1436-42. Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E. PMID: 24316081.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    81. Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc. Am J Physiol Cell Physiol. 2014 Mar 01; 306(5):C450-9. Mitchell CJ, Shawki A, Ganz T, Nemeth E, Mackenzie B. PMID: 24304836.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    82. Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6. Infect Immun. 2014 Feb; 82(2):745-52. Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y. PMID: 24478088.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    83. Systemic iron homeostasis. Physiol Rev. 2013 Oct; 93(4):1721-41. Ganz T. PMID: 24137020.
      View in: PubMed   Mentions: 204     Fields:    Translation:HumansCells
    84. Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 2013 Sep; 100(5):519-26. Clark RJ, Preza GC, Tan CC, van Dijk JW, Fung E, Nemeth E, Ganz T, Craik DJ. PMID: 23897622.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    85. Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age. Haematologica. 2013 Oct; 98(10):1633-40. McCranor BJ, Langdon JM, Prince OD, Femnou LK, Berger AE, Cheadle C, Civin CI, Kim A, Rivera S, Ganz T, Vaulont S, Xue QL, Walston JD, Roy CN. PMID: 23996485.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    86. Cellular catabolism of the iron-regulatory peptide hormone hepcidin. PLoS One. 2013; 8(3):e58934. Preza GC, Pinon R, Ganz T, Nemeth E. PMID: 23536837.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    87. Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy. Haematologica. 2013 Aug; 98(8):1324-30. Mast AE, Schlumpf KS, Wright DJ, Johnson B, Glynn SA, Busch MP, Olbina G, Westerman M, Nemeth E, Ganz T. PMID: 23445875.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    88. High-throughput screening of small molecules identifies hepcidin antagonists. Mol Pharmacol. 2013 Mar; 83(3):681-90. Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. PMID: 23292796.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    89. Preface: iron and cancer. Crit Rev Oncog. 2013; 18(5):preceding 391. Ganz T. PMID: 23879592.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    90. Hepcidin is a key mediator of anemia of inflammation in Crohn's disease. J Crohns Colitis. 2013 Sep; 7(8):e286-91. Basseri RJ, Nemeth E, Vassilaki ME, Basseri B, Enayati P, Shaye O, Bourikas LA, Ganz T, Papadakis KA. PMID: 23219355.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    91. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 2012 Nov 01; 120(18):3829-36. Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. PMID: 22990014.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    92. Iron homeostasis and its disorders in mice and men: potential lessons for rhinos. J Zoo Wildl Med. 2012 Sep; 43(3 Suppl):S19-26. Ganz T, Nemeth E. PMID: 23156702.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    93. IOD in rhinos--immunity group report: report from the Immunity, Genetics and Toxicology Working Group of the International Workshop on Iron Overload Disorder in Browsing Rhinoceros (February 2011). J Zoo Wildl Med. 2012 Sep; 43(3 Suppl):S117-9. Ganz T, Goff J, Klasing K, Nemeth E, Roth T. PMID: 23156715.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    94. Inhibition of hepcidin transcription by growth factors. Hepatology. 2012 Jul; 56(1):291-9. Goodnough JB, Ramos E, Nemeth E, Ganz T. PMID: 22278715.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    95. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metab. 2012 Jun 06; 15(6):905-17. Ross SL, Tran L, Winters A, Lee KJ, Plewa C, Foltz I, King C, Miranda LP, Allen J, Beckman H, Cooke KS, Moody G, Sasu BJ, Nemeth E, Ganz T, Molineux G, Arvedson TL. PMID: 22682226.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    96. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab. 2012 Jun 06; 15(6):918-24. Qiao B, Sugianto P, Fung E, Del-Castillo-Rueda A, Moran-Jimenez MJ, Ganz T, Nemeth E. PMID: 22682227.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    97. Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling. Blood. 2012 Jul 12; 120(2):431-9. Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H. PMID: 22611157.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    98. Hepcidin expression in iron overload diseases is variably modulated by circulating factors. PLoS One. 2012; 7(5):e36425. Ravasi G, Pelucchi S, Trombini P, Mariani R, Tomosugi N, Modignani GL, Pozzi M, Nemeth E, Ganz T, Hayashi H, Barisani D, Piperno A. PMID: 22586470.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    99. Iron metabolism: interactions with normal and disordered erythropoiesis. Cold Spring Harb Perspect Med. 2012 May; 2(5):a011668. Ganz T, Nemeth E. PMID: 22553501.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    100. Macrophages and systemic iron homeostasis. J Innate Immun. 2012; 4(5-6):446-53. Ganz T. PMID: 22441209.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    101. Hepcidin and iron homeostasis. Biochim Biophys Acta. 2012 Sep; 1823(9):1434-43. Ganz T, Nemeth E. PMID: 22306005.
      View in: PubMed   Mentions: 224     Fields:    Translation:HumansAnimalsCells
    102. Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest. 2011 Dec; 121(12):4880-8. Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, Nemeth E. PMID: 22045566.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    103. Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood. 2011 Nov 10; 118(19):5278-82. Gordeuk VR, Miasnikova GY, Sergueeva AI, Niu X, Nouraie M, Okhotin DJ, Polyakova LA, Ammosova T, Nekhai S, Ganz T, Prchal JT. PMID: 21876117.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    104. Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors. Haematologica. 2011 Aug; 96(8):1099-105. Pasricha SR, McQuilten Z, Westerman M, Keller A, Nemeth E, Ganz T, Wood E. PMID: 21508121.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    105. Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome. Liver Int. 2011 Aug; 31(7):994-1000. Trombini P, Paolini V, Pelucchi S, Mariani R, Nemeth E, Ganz T, Piperno A. PMID: 21733088.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    106. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology. 2011 Apr; 53(4):1333-41. Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T. PMID: 21480335.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    107. Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chem Biol. 2011 Mar 25; 18(3):336-43. Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, Craik DJ. PMID: 21439478.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    108. Hepcidin and iron regulation, 10 years later. Blood. 2011 Apr 28; 117(17):4425-33. Ganz T. PMID: 21346250.
      View in: PubMed   Mentions: 211     Fields:    Translation:Humans
    109. Increased serum hepcidin levels during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndrome. Br J Haematol. 2011 Apr; 153(1):118-20. Ghoti H, Fibach E, Westerman M, Gordana O, Ganz T, Rachmilewitz EA. PMID: 21332711.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    110. Hepcidin and disorders of iron metabolism. Annu Rev Med. 2011; 62:347-60. Ganz T, Nemeth E. PMID: 20887198.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    111. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematology Am Soc Hematol Educ Program. 2011; 2011:538-42. Ganz T, Nemeth E. PMID: 22160086.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    112. A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis. Haematologica. 2011 Apr; 96(4):500-6. Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C. PMID: 21173098.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    113. Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project. Blood. 2011 Mar 10; 117(10):2953-9. Piperno A, Galimberti S, Mariani R, Pelucchi S, Ravasi G, Lombardi C, Bilo G, Revera M, Giuliano A, Faini A, Mainini V, Westerman M, Ganz T, Valsecchi MG, Mancia G, Parati G. PMID: 21149632.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    114. Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 2010 Dec 02; 116(23):4754-61. Goodnough LT, Nemeth E, Ganz T. PMID: 20826717.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    115. In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood. 2010 Nov 04; 116(18):3635-44. Maes K, Nemeth E, Roodman GD, Huston A, Esteve F, Freytes C, Callander N, Katodritou E, Tussing-Humphreys L, Rivera S, Vanderkerken K, Lichtenstein A, Ganz T. PMID: 20679527.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    116. Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis. J Clin Endocrinol Metab. 2010 Oct; 95(10):4743-7. Bachman E, Feng R, Travison T, Li M, Olbina G, Ostland V, Ulloor J, Zhang A, Basaria S, Ganz T, Westerman M, Bhasin S. PMID: 20660052.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    117. Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobium. Am J Clin Nutr. 2010 Jun; 91(6):1784-90. Ayoya MA, Spiekermann-Brouwer GM, Stoltzfus RJ, Nemeth E, Habicht JP, Ganz T, Rawat R, Traoré AK, Garza C. PMID: 20410090.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    118. Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clin J Am Soc Nephrol. 2010 Jun; 5(6):1010-4. Zaritsky J, Young B, Gales B, Wang HJ, Rastogi A, Westerman M, Nemeth E, Ganz T, Salusky IB. PMID: 20299375.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    119. Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier. Am J Respir Crit Care Med. 2010 May 01; 181(9):935-46. Bdeir K, Higazi AA, Kulikovskaya I, Christofidou-Solomidou M, Vinogradov SA, Allen TC, Idell S, Linzmeier R, Ganz T, Cines DB. PMID: 20093642.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    120. Proinflammatory state, hepcidin, and anemia in older persons. Blood. 2010 May 06; 115(18):3810-6. Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL. PMID: 20081092.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    121. Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica. 2009 Dec; 94(12):1748-52. Kroot JJ, Kemna EH, Bansal SS, Busbridge M, Campostrini N, Girelli D, Hider RC, Koliaraki V, Mamalaki A, Olbina G, Tomosugi N, Tselepis C, Ward DG, Ganz T, Hendriks JC, Swinkels DW. PMID: 19996119.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    122. The role of hepcidin in iron metabolism. Acta Haematol. 2009; 122(2-3):78-86. Nemeth E, Ganz T. PMID: 19907144.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    123. Animal models of anemia of inflammation. Semin Hematol. 2009 Oct; 46(4):351-7. Rivera S, Ganz T. PMID: 19786203.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    124. Iron sequestration and anemia of inflammation. Semin Hematol. 2009 Oct; 46(4):387-93. Ganz T, Nemeth E. PMID: 19786207.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    125. Reduced serum hepcidin levels in patients with chronic hepatitis C. J Hepatol. 2009 Nov; 51(5):845-52. Girelli D, Pasino M, Goodnough JB, Nemeth E, Guido M, Castagna A, Busti F, Campostrini N, Martinelli N, Vantini I, Corrocher R, Ganz T, Fattovich G. PMID: 19729219.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    126. Sequential evaluation of serum hepcidin in anemic myeloma patients: study of correlations with myeloma treatment, disease variables, and anemia response. Am J Hematol. 2009 Aug; 84(8):524-6. Katodritou E, Ganz T, Terpos E, Verrou E, Olbina G, Gastari V, Hadjiaggelidou C, Varthaliti M, Georgiadou S, Westerman M, Zervas K. PMID: 19536845.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    127. Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation. Blood. 2009 Jul 09; 114(2):493-4. Sham RL, Phatak PD, Nemeth E, Ganz T. PMID: 19589941.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    128. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood. 2009 Jul 02; 114(1):181-6. Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL. PMID: 19414861.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    129. Hepcidin--a potential novel biomarker for iron status in chronic kidney disease. Clin J Am Soc Nephrol. 2009 Jun; 4(6):1051-6. Zaritsky J, Young B, Wang HJ, Westerman M, Olbina G, Nemeth E, Ganz T, Rivera S, Nissenson AR, Salusky IB. PMID: 19406957.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCTClinical Trials
    130. The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 2009 Jul 09; 114(2):437-43. Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, Nemeth E. PMID: 19383972.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    131. Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin. J Hepatol. 2009 Jun; 50(6):1219-25. Ruivard M, Lainé F, Ganz T, Olbina G, Westerman M, Nemeth E, Rambeau M, Mazur A, Gerbaud L, Tournilhac V, Abergel A, Philippe P, Deugnier Y, Coudray C. PMID: 19398238.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    132. Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. Eur J Appl Physiol. 2009 Jun; 106(3):435-43. Troadec MB, Lainé F, Daniel V, Rochcongar P, Ropert M, Cabillic F, Perrin M, Morcet J, Loréal O, Olbina G, Westerman M, Nemeth E, Ganz T, Brissot P. PMID: 19306018.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    133. Iron in innate immunity: starve the invaders. Curr Opin Immunol. 2009 Feb; 21(1):63-7. Ganz T. PMID: 19231148.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimals
    134. Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7). J Biol Chem. 2009 Mar 27; 284(13):8301-11. Wilson CL, Schmidt AP, Pirilä E, Valore EV, Ferri N, Sorsa T, Ganz T, Parks WC. PMID: 19181662.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    135. Immunoassay for human serum hepcidin. Blood. 2008 Nov 15; 112(10):4292-7. Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. PMID: 18689548.
      View in: PubMed   Mentions: 197     Fields:    Translation:Humans
    136. The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metab. 2008 Aug; 8(2):146-56. De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. PMID: 18680715.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    137. Involvement of hepcidin in the anemia of multiple myeloma. Clin Cancer Res. 2008 Jun 01; 14(11):3262-7. Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A. PMID: 18519751.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    138. Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. Br J Haematol. 2008 Aug; 142(4):669-71. Winder A, Lefkowitz R, Ghoti H, Leiba M, Ganz T, Nemeth E, Rachmilewitz EA. PMID: 18498424.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    139. Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload. J Hepatol. 2008 Jul; 49(1):123-33. Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, Fumagalli D, Meneveri R, Nemeth E, Ganz T, Piperno A. PMID: 18462824.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    140. Iron homeostasis: fitting the puzzle pieces together. Cell Metab. 2008 Apr; 7(4):288-90. Ganz T. PMID: 18396134.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    141. Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis. Blood Cells Mol Dis. 2008 May-Jun; 40(3):347-52. Bozzini C, Campostrini N, Trombini P, Nemeth E, Castagna A, Tenuti I, Corrocher R, Camaschella C, Ganz T, Olivieri O, Piperno A, Girelli D. PMID: 18164223.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    142. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest. 2007 Nov; 117(11):3339-49. Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. PMID: 17975669.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    143. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol. 2008 Apr; 128(4):917-25. Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, Elias PM. PMID: 17943185.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    144. Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia. Haematologica. 2007 Oct; 92(10):1407-10. Trombini P, Coliva T, Nemeth E, Mariani R, Ganz T, Biondi A, Piperno A. PMID: 17768112.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    145. Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin. Blood Cells Mol Dis. 2008 Jan-Feb; 40(1):132-8. Valore EV, Ganz T. PMID: 17905609.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    146. Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer. Mol Immunol. 2008 Feb; 45(3):839-48. Bullard RS, Gibson W, Bose SK, Belgrave JK, Eaddy AC, Wright CJ, Hazen-Martin DJ, Lage JM, Keane TE, Ganz TA, Donald CD. PMID: 17868871.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    147. Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Blood Cells Mol Dis. 2008 Jan-Feb; 40(1):122-31. Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T. PMID: 17869549.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    148. Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis. Blood. 2007 Dec 01; 110(12):4096-100. Piperno A, Girelli D, Nemeth E, Trombini P, Bozzini C, Poggiali E, Phung Y, Ganz T, Camaschella C. PMID: 17724144.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    149. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med. 2007 Sep; 13(9):1096-101. Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, Miller JL. PMID: 17721544.
      View in: PubMed   Mentions: 232     Fields:    Translation:HumansCells
    150. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 2007 Sep 15; 110(6):2182-9. Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T. PMID: 17540841.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    151. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell. 2007 Jul; 18(7):2569-78. De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. PMID: 17475779.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    152. Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica. 2007 May; 92(5):583-8. Origa R, Galanello R, Ganz T, Giagu N, Maccioni L, Faa G, Nemeth E. PMID: 17488680.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    153. Molecular control of iron transport. J Am Soc Nephrol. 2007 Feb; 18(2):394-400. Ganz T. PMID: 17229910.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    154. Urinary hepcidin in congenital chronic anemias. Pediatr Blood Cancer. 2007 Jan; 48(1):57-63. Kearney SL, Nemeth E, Neufeld EJ, Thapa D, Ganz T, Weinstein DA, Cunningham MJ. PMID: 16220548.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCTClinical Trials
    155. Reversible deficiency of antimicrobial polypeptides in bacterial vaginosis. Infect Immun. 2006 Oct; 74(10):5693-702. Valore EV, Wiley DJ, Ganz T. PMID: 16988245.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    156. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. J Immunol. 2006 Aug 01; 177(3):1864-71. Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. PMID: 16849498.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    157. Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica. 2006 Aug; 91(8):1092-5. De Domenico I, McVey Ward D, Nemeth E, Ganz T, Corradini E, Ferrara F, Musci G, Pietrangelo A, Kaplan J. PMID: 16885049.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    158. Suppression of hepcidin during anemia requires erythropoietic activity. Blood. 2006 Dec 01; 108(12):3730-5. Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S. PMID: 16882706.
      View in: PubMed   Mentions: 159     Fields:    Translation:Animals
    159. DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood. 2006 Jul 01; 108(1):404-5. Pospisilova D, Mims MP, Nemeth E, Ganz T, Prchal JT. PMID: 16790587.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    160. Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor. J Clin Invest. 2006 Jul; 116(7):1878-85. Sørensen OE, Thapa DR, Roupé KM, Valore EV, Sjöbring U, Roberts AA, Schmidtchen A, Ganz T. PMID: 16778986.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    161. Hepcidin and iron-loading anemias. Haematologica. 2006 Jun; 91(6):727-32. Nemeth E, Ganz T. PMID: 16769573.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    162. Regulation of iron acquisition and iron distribution in mammals. Biochim Biophys Acta. 2006 Jul; 1763(7):690-9. Ganz T, Nemeth E. PMID: 16790283.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    163. Molecular pathogenesis of anemia of chronic disease. Pediatr Blood Cancer. 2006 May 01; 46(5):554-7. Ganz T. PMID: 16261603.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    164. Copy number polymorphisms are not a common feature of innate immune genes. Genomics. 2006 Jul; 88(1):122-6. Linzmeier RM, Ganz T. PMID: 16617005.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    165. Iron imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol. 2006 Feb; 290(2):G199-203. Ganz T, Nemeth E. PMID: 16407589.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    166. Hepcidin--a peptide hormone at the interface of innate immunity and iron metabolism. Curr Top Microbiol Immunol. 2006; 306:183-98. Ganz T. PMID: 16909922.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    167. Hepcidin and its role in regulating systemic iron metabolism. Hematology Am Soc Hematol Educ Program. 2006; 29-35, 507. Ganz T. PMID: 17124036.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    168. Regulation of iron metabolism by hepcidin. Annu Rev Nutr. 2006; 26:323-42. Nemeth E, Ganz T. PMID: 16848710.
      View in: PubMed   Mentions: 174     Fields:    Translation:Humans
    169. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18129-34. Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Fellermann K, Ganz T, Stange EF, Bevins CL. PMID: 16330776.
      View in: PubMed   Mentions: 269     Fields:    Translation:HumansAnimalsCells
    170. A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron. Blood. 2005 Oct 15; 106(8):2922-3. Porto G, Roetto A, Daraio F, Pinto JP, Almeida S, Bacelar C, Nemeth E, Ganz T, Camaschella C. PMID: 16204153.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    171. Decreased clearance of Pseudomonas aeruginosa from airways of mice deficient in lysozyme M. J Leukoc Biol. 2005 Nov; 78(5):1081-5. Cole AM, Thapa DR, Gabayan V, Liao HI, Liu L, Ganz T. PMID: 16204648.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    172. Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23. Genomics. 2005 Oct; 86(4):423-30. Linzmeier RM, Ganz T. PMID: 16039093.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    173. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood. 2006 Jan 01; 107(1):328-33. Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T. PMID: 16141345.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    174. Distinct defensin profiles in Neisseria gonorrhoeae and Chlamydia trachomatis urethritis reveal novel epithelial cell-neutrophil interactions. Infect Immun. 2005 Aug; 73(8):4823-33. Porter E, Yang H, Yavagal S, Preza GC, Murillo O, Lima H, Greene S, Mahoozi L, Klein-Patel M, Diamond G, Gulati S, Ganz T, Rice PA, Quayle AJ. PMID: 16040996.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    175. Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease. Hepatology. 2005 Aug; 42(2):466-72. Zoller H, McFarlane I, Theurl I, Stadlmann S, Nemeth E, Oxley D, Ganz T, Halsall DJ, Cox TM, Vogel W. PMID: 15986403.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    176. Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood. 2005 Oct 15; 106(8):2884-9. Lin L, Goldberg YP, Ganz T. PMID: 15998830.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    177. The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci U S A. 2005 Jun 21; 102(25):8955-60. De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, Kaplan J. PMID: 15956209.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    178. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood. 2005 Sep 15; 106(6):2196-9. Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T. PMID: 15933050.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    179. Hepcidin--a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol. 2005 Jun; 18(2):171-82. Ganz T. PMID: 15737883.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    180. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005 May 15; 174(10):6137-43. Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL. PMID: 15879109.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    181. Defensins and other antimicrobial peptides: a historical perspective and an update. Comb Chem High Throughput Screen. 2005 May; 8(3):209-17. Ganz T. PMID: 15892623.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    182. Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6843-8. Liuzzi JP, Lichten LA, Rivera S, Blanchard RK, Aydemir TB, Knutson MD, Ganz T, Cousins RJ. PMID: 15863613.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    183. Differential regulation of beta-defensin expression in human skin by microbial stimuli. J Immunol. 2005 Apr 15; 174(8):4870-9. Sørensen OE, Thapa DR, Rosenthal A, Liu L, Roberts AA, Ganz T. PMID: 15814714.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    184. Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood. 2005 Jul 15; 106(2):746-8. Détivaud L, Nemeth E, Boudjema K, Turlin B, Troadec MB, Leroyer P, Ropert M, Jacquelinet S, Courselaud B, Ganz T, Brissot P, Loréal O. PMID: 15797999.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    185. Cellular iron: ferroportin is the only way out. Cell Metab. 2005 Mar; 1(3):155-7. Ganz T. PMID: 16054057.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    186. Hepcidin in iron overload disorders. Blood. 2005 May 15; 105(10):4103-5. Papanikolaou G, Tzilianos M, Christakis JI, Bogdanos D, Tsimirika K, MacFarlane J, Goldberg YP, Sakellaropoulos N, Ganz T, Nemeth E. PMID: 15671438.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    187. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004 Dec 17; 306(5704):2090-3. Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. PMID: 15514116.
      View in: PubMed   Mentions: 1145     Fields:    Translation:HumansAnimalsCells
    188. Increased bronchoalveolar lavage human beta-defensin type 2 in bronchiolitis obliterans syndrome after lung transplantation. Transplantation. 2004 Oct 27; 78(8):1222-4. Ross DJ, Cole AM, Yoshioka D, Park AK, Belperio JA, Laks H, Strieter RM, Lynch JP, Kubak B, Ardehali A, Ganz T. PMID: 15502724.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    189. Hepcidin is decreased in TFR2 hemochromatosis. Blood. 2005 Feb 15; 105(4):1803-6. Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. PMID: 15486069.
      View in: PubMed   Mentions: 127     Fields:    Translation:Humans
    190. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005 Feb 15; 105(4):1797-802. Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. PMID: 15479721.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    191. Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis. Ann Allergy Asthma Immunol. 2004 Sep; 93(3):288-92. Kalfa VC, Spector SL, Ganz T, Cole AM. PMID: 15478391.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    192. Hepcidin in iron metabolism. Curr Opin Hematol. 2004 Jul; 11(4):251-4. Ganz T. PMID: 15314524.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    193. Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5'-UTR of the HAMP gene. Blood. 2004 Oct 01; 104(7):2181-3. Matthes T, Aguilar-Martinez P, Pizzi-Bosman L, Darbellay R, Rubbia-Brandt L, Giostra E, Michel M, Ganz T, Beris P. PMID: 15198949.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    194. Defensins: antimicrobial peptides of vertebrates. C R Biol. 2004 Jun; 327(6):539-49. Ganz T. PMID: 15330253.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    195. Antimicrobial activity of innate immune molecules against Streptococcus pneumoniae, Moraxella catarrhalis and nontypeable Haemophilus influenzae. BMC Infect Dis. 2004 May 05; 4:12. Lee HY, Andalibi A, Webster P, Moon SK, Teufert K, Kang SH, Li JD, Nagura M, Ganz T, Lim DJ. PMID: 15125783.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    196. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004 May; 113(9):1271-6. Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. PMID: 15124018.
      View in: PubMed   Mentions: 579     Fields:    Translation:HumansAnimalsCells
    197. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. J Immunol. 2003 Dec 15; 171(12):6820-6. Hertz CJ, Wu Q, Porter EM, Zhang YJ, Weismüller KH, Godowski PJ, Ganz T, Randell SH, Modlin RL. PMID: 14662888.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    198. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004 Jan; 36(1):77-82. Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dubé MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR, Goldberg YP. PMID: 14647275.
      View in: PubMed   Mentions: 248     Fields:    Translation:HumansCells
    199. Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol. 2003 Sep; 3(9):710-20. Ganz T. PMID: 12949495.
      View in: PubMed   Mentions: 736     Fields:    Translation:HumansAnimalsCells
    200. Antimicrobial polypeptides. J Leukoc Biol. 2004 Jan; 75(1):34-8. Ganz T. PMID: 12960278.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    201. Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol. 2003 Jun 01; 170(11):5583-9. Sørensen OE, Cowland JB, Theilgaard-Mönch K, Liu L, Ganz T, Borregaard N. PMID: 12759437.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    202. Microbiology: Gut defence. Nature. 2003 Apr 03; 422(6931):478-9. Ganz T. PMID: 12673233.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    203. Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas. Lab Invest. 2003 Apr; 83(4):501-5. Donald CD, Sun CQ, Lim SD, Macoska J, Cohen C, Amin MB, Young AN, Ganz TA, Marshall FF, Petros JA. PMID: 12695553.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    204. The role of antimicrobial peptides in innate immunity. Integr Comp Biol. 2003 Apr; 43(2):300-4. Ganz T. PMID: 21680437.
      View in: PubMed   Mentions: 51     Fields:    
    205. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood. 2003 Aug 01; 102(3):783-8. Ganz T. PMID: 12663437.
      View in: PubMed   Mentions: 258     Fields:    Translation:Humans
    206. Angiogenin: an antimicrobial ribonuclease. Nat Immunol. 2003 Mar; 4(3):213-4. Ganz T. PMID: 12605229.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    207. Antibacterial activity of peptides derived from envelope glycoproteins of HIV-1. FEBS Lett. 2003 Jan 30; 535(1-3):195-9. Cole AM, Liao HI, Ganz T, Yang OO. PMID: 12560103.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    208. Expression of antimicrobial defensins in the male reproductive tract of rats, mice, and humans. Biol Reprod. 2003 Jan; 68(1):95-104. Com E, Bourgeon F, Evrard B, Ganz T, Colleu D, Jégou B, Pineau C. PMID: 12493700.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    209. By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol. 2003 Jan 01; 170(1):575-80. Liu L, Roberts AA, Ganz T. PMID: 12496445.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    210. Cationic polypeptides are required for antibacterial activity of human airway fluid. J Immunol. 2002 Dec 15; 169(12):6985-91. Cole AM, Liao HI, Stuchlik O, Tilan J, Pohl J, Ganz T. PMID: 12471133.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    211. A model for antimicrobial gene therapy: demonstration of human beta-defensin 2 antimicrobial activities in vivo. Hum Gene Ther. 2002 Nov 20; 13(17):2017-25. Huang GT, Zhang HB, Kim D, Liu L, Ganz T. PMID: 12489997.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    212. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003 Apr 01; 101(7):2461-3. Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. PMID: 12433676.
      View in: PubMed   Mentions: 334     Fields:    Translation:HumansCells
    213. Immunology. Versatile defensins. Science. 2002 Nov 01; 298(5595):977-9. Ganz T. PMID: 12411693.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    214. The role of hepcidin in iron sequestration during infections and in the pathogenesis of anemia of chronic disease. Isr Med Assoc J. 2002 Nov; 4(11):1043-5. Ganz T. PMID: 12489503.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    215. Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan. Blood. 2003 Mar 15; 101(6):2388-92. Ganz T, Gabayan V, Liao HI, Liu L, Oren A, Graf T, Cole AM. PMID: 12411294.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    216. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med. 2002 Oct 10; 347(15):1151-60. Ong PY, Ohtake T, Brandt C, Strickland I, Boguniewicz M, Ganz T, Gallo RL, Leung DY. PMID: 12374875.
      View in: PubMed   Mentions: 399     Fields:    Translation:HumansCells
    217. Antimicrobial components of vaginal fluid. Am J Obstet Gynecol. 2002 Sep; 187(3):561-8. Valore EV, Park CH, Igreti SL, Ganz T. PMID: 12237628.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    218. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem. 2002 Oct 04; 277(40):37597-603. Hunter HN, Fulton DB, Ganz T, Vogel HJ. PMID: 12138110.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    219. Antimicrobial factors in the cervical mucus plug. Am J Obstet Gynecol. 2002 Jul; 187(1):137-44. Hein M, Valore EV, Helmig RB, Uldbjerg N, Ganz T. PMID: 12114901.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    220. Activation of a Src-dependent Raf-MEK1/2-ERK signaling pathway is required for IL-1alpha-induced upregulation of beta-defensin 2 in human middle ear epithelial cells. Biochim Biophys Acta. 2002 Jun 12; 1590(1-3):41-51. Moon SK, Lee HY, Li JD, Nagura M, Kang SH, Chun YM, Linthicum FH, Ganz T, Andalibi A, Lim DJ. PMID: 12063167.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    221. Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol. 2002 Jun; 3(6):583-90. Ghosh D, Porter E, Shen B, Lee SK, Wilk D, Drazba J, Yadav SP, Crabb JW, Ganz T, Bevins CL. PMID: 12021776.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    222. Neutrophil defense in patients undergoing bone marrow transplantation: bactericidal/permeability-increasing protein (BPI) and defensins in graft-derived neutrophils. Transplantation. 2002 May 15; 73(9):1522-6. Levy O, Sisson RB, Fryer HE, Goldmann D, Valore E, Ganz T, White ML, Carroll SF, Lehmann L, Guinan EC. PMID: 12023636.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    223. Epithelia: not just physical barriers. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3357-8. Ganz T. PMID: 11904396.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    224. Using a collaborative weaning plan to decrease duration of mechanical ventilation and length of stay in the intensive care unit for patients receiving long-term ventilation. Am J Crit Care. 2002 Mar; 11(2):132-40. Henneman E, Dracup K, Ganz T, Molayeme O, Cooper CB. PMID: 11888125.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    225. Antimicrobial polypeptides in host defense of the respiratory tract. J Clin Invest. 2002 Mar; 109(6):693-7. Ganz T. PMID: 11901174.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    226. Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation. J Invest Dermatol. 2002 Feb; 118(2):275-81. Liu AY, Destoumieux D, Wong AV, Park CH, Valore EV, Liu L, Ganz T. PMID: 11841544.
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    227. Defensins of vertebrate animals. Curr Opin Immunol. 2002 Feb; 14(1):96-102. Lehrer RI, Ganz T. PMID: 11790538.
      View in: PubMed   Mentions: 157     Fields:    Translation:Animals
    228. Overexpression and structural study of the cathelicidin motif of the protegrin-3 precursor. Biochemistry. 2002 Jan 08; 41(1):21-30. Sanchez JF, Wojcik F, Yang YS, Strub MP, Strub JM, Van Dorsselaer A, Martin M, Lehrer R, Ganz T, Chavanieu A, Calas B, Aumelas A. PMID: 11771999.
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    229. Cathelicidins: a family of endogenous antimicrobial peptides. Curr Opin Hematol. 2002 Jan; 9(1):18-22. Lehrer RI, Ganz T. PMID: 11753073.
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    230. Antimicrobial peptides and proteins in the CF airway. Methods Mol Med. 2002; 70:447-64. Cole AM, Ganz T. PMID: 11917542.
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    231. Fatal attraction evaded. How pathogenic bacteria resist cationic polypeptides. J Exp Med. 2001 May 07; 193(9):F31-4. Ganz T. PMID: 11342596.
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    232. Defensins in the urinary tract and other tissues. J Infect Dis. 2001 Mar 01; 183 Suppl 1:S41-2. Ganz T. PMID: 11171012.
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    233. Defensins and host defense. Science. 1999 Oct 15; 286(5439):420-1. Ganz T. PMID: 10577203.
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