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Lee Wai-Nang Paul

Title(s)Chief, ENDOCRINOLOGY/METABOLISM
SchoolThe Lundquist Institute for Biomedical Innovation
Phone(310) 533-0627
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    1. Patterson ME, Yee JK, Wahjudi P, Mao CS, Lee WP. Acute metabolic responses to high fructose corn syrup ingestion in adolescents with overweight/obesity and diabetes. J Nutr Intermed Metab. 2018 Dec; 14:1-7. PMID: 31058204.
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    2. Jia Y, Yee JK, Wang C, Nikolaenko L, Diaz-Arjonilla M, Cohen JN, French SW, Liu PY, Lue Y, Lee WP, Swerdloff RS. Testosterone protects high-fat/low-carbohydrate diet-induced nonalcoholic fatty liver disease in castrated male rats mainly via modulating endoplasmic reticulum stress. Am J Physiol Endocrinol Metab. 2018 04 01; 314(4):E366-E376. PMID: 28928235.
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    3. Xiao GG, Wang H, Wang L, Zhang W, Gao G, Zhang X, Lee WP, Lu Z, Chen J, Gao P, Lu B, Tang KF, Shi L, Go VLW. Proceedings of the 1st International Conference for Cancer Metabolism and Therapy, October 14-17, 2016, Dalian, China. Pancreas. 2017 08; 46(7):953-963. PMID: 28697138.
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    4. Yee JK, Han G, Vega J, Lee WP, Ross MG, Desai M. Fatty Acid de Novo Synthesis in Adult Intrauterine Growth-Restricted Offspring, and Adult Male Response to a High Fat Diet. Lipids. 2016 Dec; 51(12):1339-1351. PMID: 27660207.
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    5. Zhang X, Duan W, Lee WN, Zhang Y, Xiang F, Liu Q, Go VL, Xiao GG. Overexpression of p53 Improves Blood Glucose Control in an Insulin Resistant Diabetic Mouse Model. Pancreas. 2016 08; 45(7):1010-7. PMID: 27101570.
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    6. Ma SX, Peterson RG, Magee EM, Lee P, Lee WN, Li XY. Impaired expression of neuronal nitric oxide synthase in the gracile nucleus is involved in neuropathic changes in Zucker Diabetic Fatty rats with and without 2,5-hexanedione intoxication. Neurosci Res. 2016 May; 106:47-54. PMID: 26519861.
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    7. Lu QY, Zhang L, Yee JK, Go VW, Lee WN. Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells. Metabolomics. 2015 Feb; 11(1):71-80. PMID: 26246802.
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    8. Panosyan EH, Wang Y, Xia P, Lee WN, Pak Y, Laks DR, Lin HJ, Moore TB, Cloughesy TF, Kornblum HI, Lasky JL. Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors. Mol Cancer Res. 2014 May; 12(5):694-702. PMID: 24505127.
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    9. Yee JK, Wahjudi PN, Vega J, Lim S, Martin A, Patterson ME, Cohen JN, Mao CS, Lee WN. Stearoyl-CoA desaturase enzyme 1 inhibition reduces glucose utilization for de novo fatty acid synthesis and cell proliferation in 3T3-L1 adipocytes. Metabolomics. 2013 Aug 01; 9(4):809-816. PMID: 24039619.
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    10. Yee JK, Lee WN, Ross MG, Lane RH, Han G, Vega J, Desai M. Peroxisome proliferator-activated receptor gamma modulation and lipogenic response in adipocytes of small-for-gestational age offspring. Nutr Metab (Lond). 2012 Jun 22; 9(1):62. PMID: 22726273.
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    11. Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2011 Nov 15; 30(24):4860-73. PMID: 22085932.
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    12. Yee JK, Lee WN, Han G, Ross MG, Desai M. Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. Lipids Health Dis. 2011 May 11; 10:72. PMID: 21569358.
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    13. Paul Lee WN, Wahjudi PN, Xu J, Go VL. Tracer-based metabolomics: concepts and practices. Clin Biochem. 2010 Nov; 43(16-17):1269-77. PMID: 20713038.
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    14. Boros LG, Deng Q, Pandol SJ, Tsukamoto H, Go VL, Lee WN. Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer. Pancreas. 2009 Mar; 38(2):e47-52. PMID: 19248221.
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    15. Yee JK, Mao CS, Hummel HS, Lim S, Sugano S, Rehan VK, Xiao G, Lee WN. Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells. J Lipid Res. 2008 Oct; 49(10):2124-34. PMID: 18599738.
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    16. Xiao GG, Garg M, Lim S, Wong D, Go VL, Lee WN. Determination of protein synthesis in vivo using labeling from deuterated water and analysis of MALDI-TOF spectrum. J Appl Physiol (1985). 2008 Mar; 104(3):828-36. PMID: 18187609.
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    17. Lee WN. Characterizing phenotype with tracer based metabolomics. Metabolomics. 2006; 2:31-39. PMID: 25540606.
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    18. Go VL, Nguyen CT, Harris DM, Lee WN. Nutrient-gene interaction: metabolic genotype-phenotype relationship. J Nutr. 2005 12; 135(12 Suppl):3016S-3020S. PMID: 16317163.
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    19. Lee WN, Go VL. Nutrient-gene interaction: tracer-based metabolomics. J Nutr. 2005 12; 135(12 Suppl):3027S-3032S. PMID: 16317166.
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    20. Boros LG, Steinkamp MP, Fleming JC, Lee WN, Cascante M, Neufeld EJ. Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA). Blood. 2003 Nov 15; 102(10):3556-61. PMID: 12893755.
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    21. Boros LG, Cascante M, Lee WN. Metabolic profiling of cell growth and death in cancer: applications in drug discovery. Drug Discov Today. 2002 Mar 15; 7(6):364-72. PMID: 11893545.
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    22. Boros LG, Lee WN, Go VL. A metabolic hypothesis of cell growth and death in pancreatic cancer. Pancreas. 2002 Jan; 24(1):26-33. PMID: 11741179.
      View in: PubMed
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