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Zhenfeng Duan

Title(s)Professor-in-Residence, Orthopaedic Surgery
SchoolMedicine
Address760 Westwood Plaza 76-143
Los Angeles CA 90024
Phone3103191234
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeting cancer stem cells by disulfiram and copper sensitizes radioresistant chondrosarcoma to radiation. Cancer Lett. 2021 Feb 11. PMID: 33582212.
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    2. Prognostic Significance of Cyclin E1 Expression in Patients With Chordoma: A Clinicopathological and Immunohistochemical Study. Front Oncol. 2020; 10:596330. Wei R, Dean DC, Thanindratarn P, Hornicek FJ, Guo W, Duan Z. PMID: 33282745.
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    3. T-LAK cell-originated protein kinase (TOPK) is a Novel Prognostic and Therapeutic Target in Chordoma. Cell Prolif. 2020 Oct; 53(10):e12901. Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ, Duan Z. PMID: 32960500.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Expression and clinical implications of leucine-rich repeat containing 15 (LRRC15) in osteosarcoma. J Orthop Res. 2020 11; 38(11):2362-2372. Cui J, Dean D, Wei R, Hornicek FJ, Ulmert D, Duan Z. PMID: 32902907.
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    5. Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma. Ther Adv Med Oncol. 2020; 12:1758835920956900. Li X, Dean DC, Cote GM, Zou L, Hornicek FJ, Yu S, Duan Z. PMID: 32973933.
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    6. The role of extracelluar matrix in osteosarcoma progression and metastasis. J Exp Clin Cancer Res. 2020 Sep 04; 39(1):178. Cui J, Dean D, Hornicek FJ, Chen Z, Duan Z. PMID: 32887645.
      View in: PubMed   Mentions: 1     Fields:    
    7. PTEN in osteosarcoma: Recent advances and the therapeutic potential. Biochim Biophys Acta Rev Cancer. 2020 12; 1874(2):188405. Zheng C, Tang F, Min L, Hornicek F, Duan Z, Tu C. PMID: 32827577.
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    8. Cyclin-dependent kinase 12 (CDK12) in chordoma: prognostic and therapeutic value. Eur Spine J. 2020 Dec; 29(12):3214-3228. Thanindratarn P, Dean DC, Feng W, Wei R, Nelson SD, Hornicek FJ, Duan Z. PMID: 32691223.
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    9. Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma. Ther Adv Med Oncol. 2020; 12:1758835920922055. Feng W, Dean DC, Hornicek FJ, Spentzos D, Hoffman RM, Shi H, Duan Z. PMID: 32426053.
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    10. Cyclin E1 is a prognostic biomarker and potential therapeutic target in osteosarcoma. J Orthop Res. 2020 09; 38(9):1952-1964. Wei R, Thanindratarn P, Dean DC, Hornicek FJ, Guo W, Duan Z. PMID: 32162720.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Corrigendum to "HER4 promotes cell survival and chemoresistance in osteosarcoma via interaction with NDRG1" [Biochim. Biophys. Acta Mol. Basis Dis. 1864 (2018) 1839-1849]. Biochim Biophys Acta Mol Basis Dis. 2020 Jun 01; 1866(6):165755. Wang H, Sun W, Sun M, Fu Z, Zhou C, Wang C, Zuo D, Zhou Z, Wang G, Zhang T, Xu J, Chen J, Wang Z, Yin F, Duan Z, Hornicek FJ, Cai Z, Hua Y. PMID: 32173158.
      View in: PubMed   Mentions:    Fields:    
    12. MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma. Sci Rep. 2020 03 10; 10(1):4409. Lietz CE, Garbutt C, Barry WT, Deshpande V, Chen YL, Lozano-Calderon SA, Wang Y, Lawney B, Ebb D, Cote GM, Duan Z, Hornicek FJ, Choy E, Petur Nielsen G, Haibe-Kains B, Quackenbush J, Spentzos D. PMID: 32157112.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Switching from Fatty Acid Oxidation to Glycolysis Improves the Outcome of Acute-On-Chronic Liver Failure. Adv Sci (Weinh). 2020 Apr; 7(7):1902996. Yu Z, Li J, Ren Z, Sun R, Zhou Y, Zhang Q, Wang Q, Cui G, Li J, Li A, Duan Z, Xu Y, Wang Z, Yin P, Piao H, Lv J, Liu X, Wang Y, Fang M, Zhuang Z, Xu G, Kan Q. PMID: 32274306.
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    14. Diagnosis, Therapy, and Prognosis for Hepatocellular Carcinoma. Anal Cell Pathol (Amst). 2020; 2020:8157406. Ren Z, Ma X, Duan Z, Chen X. PMID: 32089989.
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    15. Emerging next-generation sequencing-based discoveries for targeted osteosarcoma therapy. Cancer Lett. 2020 04 01; 474:158-167. Zhao J, Dean DC, Hornicek FJ, Yu X, Duan Z. PMID: 31987920.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067. J Cancer. 2020; 11(1):132-141. Shen S, Dean DC, Yu Z, Hornicek F, Kan Q, Duan Z. PMID: 31892980.
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    17. Establishment and Characterization of a Recurrent Osteosarcoma Cell Line: OSA 1777. J Orthop Res. 2020 04; 38(4):902-910. Thanindratarn P, Li X, Dean DC, Nelson SD, Hornicek FJ, Duan Z. PMID: 31736134.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Chimeric antigen receptor T (CAR-T) cell immunotherapy for sarcomas: From mechanisms to potential clinical applications. Cancer Treat Rev. 2020 Jan; 82:101934. Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ, Duan Z. PMID: 31794912.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Correction to: Transcriptional activation of CBFß by CDK11p110 is necessary to promote osteosarcoma cell proliferation. Cell Commun Signal. 2019 Oct 29; 17(1):138. Feng Y, Liao Y, Zhang J, Shen J, Shao Z, Hornicek F, Duan Z. PMID: 31665012.
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    20. Cancer testis antigens in sarcoma: Expression, function and immunotherapeutic application. Cancer Lett. 2020 06 01; 479:54-60. Wei R, Dean DC, Thanindratarn P, Hornicek FJ, Guo W, Duan Z. PMID: 31634526.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    21. Transcriptional activation of CBFß by CDK11p110 is necessary to promote osteosarcoma cell proliferation. Cell Commun Signal. 2019 10 14; 17(1):125. Feng Y, Liao Y, Zhang J, Shen J, Shao Z, Hornicek F, Duan Z. PMID: 31610798.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Exosomes promote pre-metastatic niche formation in ovarian cancer. Mol Cancer. 2019 08 13; 18(1):124. Feng W, Dean DC, Hornicek FJ, Shi H, Duan Z. PMID: 31409361.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    23. Role of cyclin-dependent kinases (CDKs) in hepatocellular carcinoma: Therapeutic potential of targeting the CDK signaling pathway. Hepatol Res. 2019 Oct; 49(10):1097-1108. Shen S, Dean DC, Yu Z, Duan Z. PMID: 31009153.
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    24. miR3609 sensitizes breast cancer cells to adriamycin by blocking the programmed death-ligand 1 immune checkpoint. Exp Cell Res. 2019 07 01; 380(1):20-28. Li D, Wang X, Yang M, Kan Q, Duan Z. PMID: 30904483.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer. Mol Cancer. 2019 03 02; 18(1):33. Chen J, Yu Y, Li H, Hu Q, Chen X, He Y, Xue C, Ren F, Ren Z, Li J, Liu L, Duan Z, Cui G, Sun R. PMID: 30825877.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    26. Anlotinib, a novel small molecular tyrosine kinase inhibitor, suppresses growth and metastasis via dual blockade of VEGFR2 and MET in osteosarcoma. Int J Cancer. 2019 08 15; 145(4):979-993. Wang G, Sun M, Jiang Y, Zhang T, Sun W, Wang H, Yin F, Wang Z, Sang W, Xu J, Mao M, Zuo D, Zhou Z, Wang C, Fu Z, Wang Z, Duan Z, Hua Y, Cai Z. PMID: 30719715.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    27. Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma. J Orthop Res. 2019 03; 37(3):789-798. Tang F, Min L, Seebacher NA, Li X, Zhou Y, Hornicek FJ, Wei Y, Tu C, Duan Z. PMID: 30667081.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Cyclin-dependent kinase 9 (CDK9) is a novel prognostic marker and therapeutic target in ovarian cancer. FASEB J. 2019 05; 33(5):5990-6000. Wang J, Dean DC, Hornicek FJ, Shi H, Duan Z. PMID: 30726104.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    29. Advances in immune checkpoint inhibitors for bone sarcoma therapy. J Bone Oncol. 2019 Apr; 15:100221. Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ, Duan Z. PMID: 30775238.
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    30. Targeting regulation of cyclin dependent kinase 9 as a novel therapeutic strategy in synovial sarcoma. J Orthop Res. 2019 02; 37(2):510-521. Li X, Seebacher NA, Xiao T, Hornicek FJ, Duan Z. PMID: 30488489.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    31. Cyclin-dependent kinase 9 (CDK9) is a novel prognostic marker and therapeutic target in osteosarcoma. EBioMedicine. 2019 Jan; 39:182-193. Ma H, Seebacher NA, Hornicek FJ, Duan Z. PMID: 30579871.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    32. From genomics to metabolomics: emerging metastatic biomarkers in osteosarcoma. Cancer Metastasis Rev. 2018 12; 37(4):719-731. Dean DC, Shen S, Hornicek FJ, Duan Z. PMID: 30167827.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    33. RNA sequencing (RNA-Seq) and its application in ovarian cancer. Gynecol Oncol. 2019 01; 152(1):194-201. Wang J, Dean DC, Hornicek FJ, Shi H, Duan Z. PMID: 30297273.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    34. Application of liquid biopsy in bone and soft tissue sarcomas: Present and future. Cancer Lett. 2018 12 28; 439:66-77. PMID: 30223067.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    35. MiR-139-5p is associated with poor prognosis and regulates glycolysis by repressing PKM2 in gallbladder carcinoma. Cell Prolif. 2018 Dec; 51(6):e12510. Chen J, Yu Y, Chen X, He Y, Hu Q, Li H, Han Q, Ren F, Li J, Li C, Bao J, Ren Z, Duan Z, Cui G, Sun R. PMID: 30105813.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    36. Author Correction: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11. Sci Rep. 2018 Aug 09; 8(1):12107. Liao Y, Sassi S, Halvorsen S, Feng Y, Shen J, Gao Y, Cote G, Choy E, Harmon D, Mankin H, Hornicek F, Duan Z. PMID: 30093700.
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    37. Inhibition of cyclin-dependent kinase 4 as a potential therapeutic strategy for treatment of synovial sarcoma. Cell Death Dis. 2018 05 01; 9(5):446. Li X, Seebacher NA, Garbutt C, Ma H, Gao P, Xiao T, Hornicek FJ, Duan Z. PMID: 29670090.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    38. Expression and role of autophagy-associated p62 (SQSTM1) in multidrug resistant ovarian cancer. Gynecol Oncol. 2018 07; 150(1):143-150. Wang J, Garbutt C, Ma H, Gao P, Hornicek FJ, Kan Q, Shi H, Duan Z. PMID: 29699801.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    39. CRISPR-Cas9-Mediated Silencing of CD44 in Human Highly Metastatic Osteosarcoma Cells. Cell Physiol Biochem. 2018; 46(3):1218-1230. Liu T, Yan Z, Liu Y, Choy E, Hornicek FJ, Mankin H, Duan Z. PMID: 29672299.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. Expression and Clinical Implication of Autophagy-Associated Protein p62 in Osteosarcoma. Oncology. 2018; 95(1):52-60. Ma H, Li X, Wang J, Hornicek FJ, Garbutt CC, Chang X, Duan Z. PMID: 29617702.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    41. HER4 promotes cell survival and chemoresistance in osteosarcoma via interaction with NDRG1. Biochim Biophys Acta Mol Basis Dis. 2018 May; 1864(5 Pt A):1839-1849. Wang H, Sun W, Sun M, Fu Z, Zhou C, Wang C, Zuo D, Zhou Z, Wang G, Zhang T, Xu J, Chen J, Wang Z, Yin F, Duan Z, Hornicek FJ, Cai Z, Hua Y. PMID: 29524631.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    42. Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma. Biochim Biophys Acta Mol Basis Dis. 2018 May; 1864(5 Pt A):1573-1582. Zhou Y, Shen JK, Yu Z, Hornicek FJ, Kan Q, Duan Z. PMID: 29452249.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    43. CDK4 expression in chordoma: A potential therapeutic target. J Orthop Res. 2018 06; 36(6):1581-1589. PMID: 29194728.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    44. Advances in chromosomal translocations and fusion genes in sarcomas and potential therapeutic applications. Cancer Treat Rev. 2018 Feb; 63:61-70. PMID: 29247978.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    45. Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells. Oncotarget. 2018 Mar 02; 9(17):13154-13166. Chen H, Shen J, Choy E, Hornicek FJ, Shan A, Duan Z. PMID: 29568347.
      View in: PubMed   Mentions: 1     Fields:    
    46. Advances in sarcoma gene mutations and therapeutic targets. Cancer Treat Rev. 2018 Jan; 62:98-109. PMID: 29190505.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Regulation of microRNAs function by circular RNAs in human cancer. Oncotarget. 2017 Sep 08; 8(38):64622-64637. Han C, Seebacher NA, Hornicek FJ, Kan Q, Duan Z. PMID: 28969099.
      View in: PubMed   Mentions: 12     Fields:    
    48. Three-dimensional (3D) culture in sarcoma research and the clinical significance. Biofabrication. 2017 Aug 03; 9(3):032003. PMID: 28707624.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    49. Novel strategies to prevent the development of multidrug resistance (MDR) in cancer. Oncotarget. 2017 Oct 13; 8(48):84559-84571. Wang J, Seebacher N, Shi H, Kan Q, Duan Z. PMID: 29137448.
      View in: PubMed   Mentions: 19     Fields:    
    50. Noncoding RNA in drug resistant sarcoma. Oncotarget. 2017 Sep 15; 8(40):69086-69104. Li X, Shen JK, Hornicek FJ, Xiao T, Duan Z. PMID: 28978183.
      View in: PubMed   Mentions: 3     Fields:    
    51. Therapeutic applications of histone deacetylase inhibitors in sarcoma. Cancer Treat Rev. 2017 Sep; 59:33-45. PMID: 28732326.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    52. Expression and Therapeutic Potential of SOX9 in Chordoma. Clin Cancer Res. 2017 Sep 01; 23(17):5176-5186. Chen H, Garbutt CC, Spentzos D, Choy E, Hornicek FJ, Duan Z. PMID: 28606919.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    53. Aberration of p73 Promoter Methylation in Chondrosarcoma. Anticancer Res. 2017 06; 37(6):2939-2945. PMID: 28551631.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    54. An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets. J Hematol Oncol. 2017 05 15; 10(1):107. PMID: 28506242.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    55. Application of metabolomics in sarcoma: From biomarkers to therapeutic targets. Crit Rev Oncol Hematol. 2017 08; 116:1-10. PMID: 28693790.
      View in: PubMed   Mentions: 2     Fields:    
    56. Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma. Sci Rep. 2017 05 08; 7(1):1580. Liu P, Shen JK, Hornicek FJ, Liu F, Duan Z. PMID: 28484252.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    57. Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells. Oncotarget. 2017 May 02; 8(18):30276-30287. PMID: 28415820.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    58. Potentials of Long Noncoding RNAs (LncRNAs) in Sarcoma: From Biomarkers to Therapeutic Targets. Int J Mol Sci. 2017 Mar 29; 18(4). PMID: 28353666.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    59. Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11. Sci Rep. 2017 03 06; 7:43941. PMID: 28262798.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    60. Inhibition of CDK4 sensitizes multidrug resistant ovarian cancer cells to paclitaxel by increasing apoptosiss. Cell Oncol (Dordr). 2017 Jun; 40(3):209-218. PMID: 28243976.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    61. Autophagy as a potential target for sarcoma treatment. Biochim Biophys Acta Rev Cancer. 2017 Aug; 1868(1):40-50. PMID: 28242349.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    62. Facial Layer-by-Layer Engineering of Upconversion Nanoparticles for Gene Delivery: Near-Infrared-Initiated Fluorescence Resonance Energy Transfer Tracking and Overcoming Drug Resistance in Ovarian Cancer. ACS Appl Mater Interfaces. 2017 Mar 08; 9(9):7941-7949. PMID: 28177223.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    63. Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance. Oncotarget. 2016 Dec 13; 7(50):83502-83513. PMID: 27835872.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    64. Regulation of microRNA-1 (miR-1) expression in human cancer. Biochim Biophys Acta Gene Regul Mech. 2017 Feb; 1860(2):227-232. PMID: 27923712.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    65. miR-15b modulates multidrug resistance in human osteosarcoma in vitro and in vivo. Mol Oncol. 2017 02; 11(2):151-166. PMID: 28145098.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    66. Novel mechanisms and approaches to overcome multidrug resistance in the treatment of ovarian cancer. Biochim Biophys Acta. 2016 12; 1866(2):266-275. PMID: 27717733.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    67. Aberrant DNA methylations in chondrosarcoma. Epigenomics. 2016 11; 8(11):1519-1525. PMID: 27686001.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    68. Matrine induces cell cycle arrest and apoptosis with recovery of the expression of miR-126 in the A549 non-small cell lung cancer cell line. Mol Med Rep. 2016 Nov; 14(5):4042-4048. An Q, Han C, Zhou Y, Li F, Li D, Zhang X, Yu Z, Duan Z, Kan Q. PMID: 27665734.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    69. CD151-mediated adhesion is crucial to osteosarcoma pulmonary metastasis. Oncotarget. 2016 Sep 13; 7(37):60623-60638. Wang Z, Wang C, Zhou Z, Sun M, Zhou C, Chen J, Yin F, Wang H, Lin B, Zuo D, Li S, Feng L, Duan Z, Cai Z, Hua Y. PMID: 27556355.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    70. The roles and implications of exosomes in sarcoma. Cancer Metastasis Rev. 2016 09; 35(3):377-90. PMID: 27342745.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    71. The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer. Oncotarget. 2016 Jun 28; 7(26):40846-40859. PMID: 27049727.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    72. Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential. Oncotarget. 2016 Jun 21; 7(25):38333-38346. PMID: 27223261.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    73. The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma. Cancer Metastasis Rev. 2016 06; 35(2):151-63. PMID: 26669603.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    74. Cyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel. . 2016 07; 15(7):1691-701. PMID: 27207777.
      View in: PubMed   Mentions:
    75. Pharmacokinetics and tolerability of NSC23925b, a novel P-glycoprotein inhibitor: preclinical study in mice and rats. Sci Rep. 2016 05 09; 6:25659. PMID: 27157103.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    76. Targeting EZH2-mediated methylation of H3K27 inhibits proliferation and migration of Synovial Sarcoma in vitro. Sci Rep. 2016 04 29; 6:25239. PMID: 27125524.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    77. Evaluation of P-glycoprotein (Pgp) expression in human osteosarcoma by high-throughput tissue microarray. J Orthop Res. 2016 09; 34(9):1606-12. PMID: 26790551.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    78. Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma. Cancer Lett. 2016 Apr 01; 373(1):109-118. PMID: 26806808.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    79. NVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function. Br J Pharmacol. 2016 Feb; 173(3):613-26. PMID: 26603906.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    80. The Roles of Sox Family Genes in Sarcoma. Curr Drug Targets. 2016; 17(15):1761-1772. PMID: 27138764.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    81. Clinical and biological significance of PIM1 kinase in osteosarcoma. J Orthop Res. 2016 07; 34(7):1185-94. PMID: 26687194.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    82. p53 overexpression increases chemosensitivity in multidrug-resistant osteosarcoma cell lines. Cancer Chemother Pharmacol. 2016 Feb; 77(2):349-56. PMID: 26698867.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    83. CSPG4 as a prognostic biomarker in chordoma. Spine J. 2016 06; 16(6):722-7. PMID: 26689475.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    84. Targeting protein kinases to reverse multidrug resistance in sarcoma. Cancer Treat Rev. 2016 Feb; 43:8-18. PMID: 26827688.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    85. In vitro effects of mitomycin C on the proliferation of the non-small-cell lung cancer line A549. Int J Clin Exp Med. 2015; 8(11):20516-23. An Q, Han C, Zhou Y, Li F, Li D, Zhang X, Yu Z, Duan Z, Kan Q. PMID: 26884968.
      View in: PubMed   Mentions:
    86. The emerging roles and therapeutic potential of microRNAs (miRs) in liposarcoma. Discov Med. 2015 Nov; 20(111):311-24. PMID: 26645903.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    87. Near-infrared light activated delivery platform for cancer therapy. Adv Colloid Interface Sci. 2015 Dec; 226(Pt B):123-37. PMID: 26520243.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    88. Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. Sarcoma. 2015; 2015:232010. PMID: 26420980.
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    89. CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma. Sci Rep. 2015 Jun 16; 5:11365. PMID: 26079799.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    90. Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth. Sci Rep. 2015 May 20; 5:10433. Zhou Y, Han C, Li D, Yu Z, Li F, Li F, An Q, Bai H, Zhang X, Duan Z, Kan Q. PMID: 25990212.
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    91. Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma. Oncotarget. 2015 May 10; 6(13):11139-49. PMID: 25871477.
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    92. Nsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis. Int J Cancer. 2015 Oct 15; 137(8):2029-39. PMID: 25904021.
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    93. MicroRNA-155 expression is independently predictive of outcome in chordoma. Oncotarget. 2015 Apr 20; 6(11):9125-39. PMID: 25823817.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    94. Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer. Oncotarget. 2015 Apr 20; 6(11):9313-26. PMID: 25823654.
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    95. Polymeric nanoparticle-based delivery of microRNA-199a-3p inhibits proliferation and growth of osteosarcoma cells. Int J Nanomedicine. 2015; 10:2913-24. PMID: 25931818.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    96. MicroRNA-1 (miR-1) inhibits gastric cancer cell proliferation and migration by targeting MET. Tumour Biol. 2015 Sep; 36(9):6715-23. Han C, Zhou Y, An Q, Li F, Li D, Zhang X, Yu Z, Zheng L, Duan Z, Kan Q. PMID: 25874496.
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    97. Decreased expression and activation of Stat3 in severe preeclampsia. J Mol Histol. 2015 Apr; 46(2):205-19. Zhang Z, Yang X, Zhang L, Duan Z, Jia L, Wang P, Shi Y, Li Y, Gao J. PMID: 25752465.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    98. MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer. Sci Rep. 2015 Feb 17; 5:8509. PMID: 25687880.
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    99. NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivo. Gynecol Oncol. 2015 Apr; 137(1):134-42. PMID: 25677062.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    100. Targeted cancer therapy; nanotechnology approaches for overcoming drug resistance. Curr Med Chem. 2015; 22(11):1335-47. PMID: 25666804.
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    101. Phase 1 study of oral abexinostat, a histone deacetylase inhibitor, in combination with doxorubicin in patients with metastatic sarcoma. Cancer. 2015 Apr 15; 121(8):1223-30. PMID: 25536954.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    102. Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer. Pharm Res. 2015 Jun; 32(6):2097-109. PMID: 25515492.
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    103. Targeting CDK11 in osteosarcoma cells using the CRISPR-Cas9 system. J Orthop Res. 2015 Feb; 33(2):199-207. PMID: 25348612.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    104. A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells. BMC Cancer. 2014 Sep 19; 14:681. PMID: 25236161.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    105. Targeting programmed cell death ligand 1 in osteosarcoma: an auto-commentary on therapeutic potential. Oncoimmunology. 2014; 3(8):e954467. PMID: 25610746.
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    106. Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1. PLoS One. 2014; 9(7):e101283. PMID: 24983247.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    107. Role of microRNA-1 in human cancer and its therapeutic potentials. Biomed Res Int. 2014; 2014:428371. Han C, Yu Z, Duan Z, Kan Q. PMID: 24949449.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    108. MicroRNA-1 (miR-1) inhibits chordoma cell migration and invasion by targeting slug. J Orthop Res. 2014 Aug; 32(8):1075-82. PMID: 24760686.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    109. Programmed cell death ligand 1 expression in osteosarcoma. Cancer Immunol Res. 2014 Jul; 2(7):690-698. PMID: 24866169.
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    110. Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma. PLoS One. 2014; 9(4):e93996. PMID: 24695632.
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    111. Prognostic significance of miRNA-1 (miR-1) expression in patients with chordoma. J Orthop Res. 2014 May; 32(5):695-701. PMID: 24501096.
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    112. BRAF mutation in 'sarcomas': a possible method to detect de-differentiated melanomas. Histopathology. 2014 Apr; 64(5):639-46. PMID: 24117833.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    113. Development of a new pre-vascularized tissue-engineered construct using pre-differentiated rADSCs, arteriovenous vascular bundle and porous nano-hydroxyapatide-polyamide 66 scaffold. BMC Musculoskelet Disord. 2013 Nov 08; 14:318. Yang P, Huang X, Shen J, Wang C, Dang X, Mankin H, Duan Z, Wang K. PMID: 24209783.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    114. Tissue microarray immunohistochemical detection of brachyury is not a prognostic indicator in chordoma. PLoS One. 2013; 8(9):e75851. PMID: 24086644.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    115. Cyclin-dependent kinase 11 (CDK11) is crucial in the growth of liposarcoma cells. Cancer Lett. 2014 Jan 01; 342(1):104-12. PMID: 24007862.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    116. Molecular distinction of chondrosarcoma from chondroblastic osteosarcoma through IDH1/2 mutations. Am J Surg Pathol. 2013 Jun; 37(6):787-95. PMID: 23598960.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    117. Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer: a pilot study. Clin Orthop Relat Res. 2013 Mar; 471(3):915-25. PMID: 23011844.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    118. Targeting hedgehog-GLI-2 pathway in osteosarcoma. J Orthop Res. 2013 Mar; 31(3):502-9. PMID: 22968906.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    119. Systematic kinome shRNA screening identifies CDK11 (PITSLRE) kinase expression is critical for osteosarcoma cell growth and proliferation. Clin Cancer Res. 2012 Sep 01; 18(17):4580-8. PMID: 22791884.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    120. Interleukin-6 signaling pathway in targeted therapy for cancer. Cancer Treat Rev. 2012 Nov; 38(7):904-10. Guo Y, Xu F, Lu T, Duan Z, Zhang Z. PMID: 22651903.
      View in: PubMed   Mentions: 222     Fields:    Translation:HumansCells
    121. Establishment and characterization of a novel chordoma cell line: CH22. J Orthop Res. 2012 Oct; 30(10):1666-73. PMID: 22504929.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    122. MicroRNA Involvement in Osteosarcoma. Sarcoma. 2012; 2012:359739. PMID: 22550419.
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    123. Synthesis and evaluation of (2-(4-methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) isomers to reverse multidrug resistance in cancer. J Med Chem. 2012 Apr 12; 55(7):3113-21. PMID: 22400811.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    124. High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. Cancer. 2012 Jun 01; 118(11):2905-14. PMID: 22006429.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    125. Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer. PLoS One. 2011; 6(9):e24075. Milane L, Duan Z, Amiji M. PMID: 21931642.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    126. MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration. . 2011 Aug; 10(8):1337-45. PMID: 21666078.
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    127. Inhibition of polo-like kinase 1 leads to the suppression of osteosarcoma cell growth in vitro and in vivo. Anticancer Drugs. 2011 Jun; 22(5):444-53. PMID: 21399492.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    128. Recurrent chromosomal copy number alterations in sporadic chordomas. PLoS One. 2011; 6(5):e18846. PMID: 21602918.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    129. Histone deacetylase inhibitor PCI-24781 enhances chemotherapy-induced apoptosis in multidrug-resistant sarcoma cell lines. Anticancer Res. 2011 Apr; 31(4):1115-23. Yang C, Choy E, Hornicek FJ, Wood KB, Schwab JH, Liu X, Mankin H, Duan Z. PMID: 21508354.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    130. ROCK1 as a potential therapeutic target in osteosarcoma. J Orthop Res. 2011 Aug; 29(8):1259-66. Liu X, Choy E, Hornicek FJ, Yang S, Yang C, Harmon D, Mankin H, Duan Z. PMID: 21387396.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    131. Proteomic profiling of chordoma. J Surg Oncol. 2010 Dec 01; 102(7):719. DeLaney TF, Duan Z, Hornicek FJ. PMID: 21104921.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    132. Cyclin G-associated kinase is necessary for osteosarcoma cell proliferation and receptor trafficking. . 2010 Dec; 9(12):3342-50. Susa M, Choy E, Liu X, Schwab J, Hornicek FJ, Mankin H, Duan Z. PMID: 20881269.
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    133. Blockage of Stat3 with CDDO-Me inhibits tumor cell growth in chordoma. Spine (Phila Pa 1976). 2010 Aug 15; 35(18):1668-75. Yang C, Hornicek FJ, Wood KB, Schwab JH, Choy E, Mankin H, Duan Z. PMID: 20386502.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    134. Effects of siltuximab on the IL-6-induced signaling pathway in ovarian cancer. Clin Cancer Res. 2010 Dec 01; 16(23):5759-69. Guo Y, Nemeth J, O'Brien C, Susa M, Liu X, Zhang Z, Choy E, Mankin H, Hornicek F, Duan Z. PMID: 20699329.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    135. Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis. J Orthop Res. 2010 Jul; 28(7):971-8. Ryu K, Choy E, Yang C, Susa M, Hornicek FJ, Mankin H, Duan Z. PMID: 20063378.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    136. Characterization and analysis of human chordoma cell lines. Spine (Phila Pa 1976). 2010 Jun 01; 35(13):1257-64. Yang C, Hornicek FJ, Wood KB, Schwab JH, Choy E, Iafrate J, Rosenberg A, Nielsen GP, Xavier RJ, Mankin H, Duan Z. PMID: 20461036.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    137. Differential expression of microRNA (miRNA) in chordoma reveals a role for miRNA-1 in Met expression. J Orthop Res. 2010 Jun; 28(6):746-52. Duan Z, Choy E, Nielsen GP, Rosenberg A, Iafrate J, Yang C, Schwab J, Mankin H, Xavier R, Hornicek FJ. PMID: 20041488.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    138. Nanoparticles: a promising modality in the treatment of sarcomas. Pharm Res. 2011 Feb; 28(2):260-72. Susa M, Milane L, Amiji MM, Hornicek FJ, Duan Z. PMID: 20505985.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    139. Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS One. 2010 May 24; 5(5):e10764. Susa M, Iyer AK, Ryu K, Choy E, Hornicek FJ, Mankin H, Milane L, Amiji MM, Duan Z. PMID: 20520719.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    140. Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells. Cancer Chemother Pharmacol. 2011 Feb; 67(2):439-46. Yang C, Choy E, Hornicek FJ, Wood KB, Schwab JH, Liu X, Mankin H, Duan Z. PMID: 20461381.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    141. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway. BMC Cancer. 2010 May 10; 10:187. Ryu K, Susa M, Choy E, Yang C, Hornicek FJ, Mankin HJ, Duan Z. PMID: 20459702.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    142. Multidrug resistance reversal agent, NSC77037, identified with a cell-based screening assay. J Biomol Screen. 2010 Mar; 15(3):287-96. Susa M, Choy E, Yang C, Schwab J, Mankin H, Hornicek F, Duan Z. PMID: 20150589.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    143. Lentiviral shRNA screen of human kinases identifies PLK1 as a potential therapeutic target for osteosarcoma. Cancer Lett. 2010 Jul 28; 293(2):220-9. Duan Z, Ji D, Weinstein EJ, Liu X, Susa M, Choy E, Yang C, Mankin H, Hornicek FJ. PMID: 20144850.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    144. Augmentation of therapeutic efficacy in drug-resistant tumor models using ceramide coadministration in temporal-controlled polymer-blend nanoparticle delivery systems. AAPS J. 2010 Jun; 12(2):171-80. van Vlerken LE, Duan Z, Little SR, Seiden MV, Amiji MM. PMID: 20143195.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    145. The kinase Mirk is a potential therapeutic target in osteosarcoma. Carcinogenesis. 2010 Apr; 31(4):552-8. Yang C, Ji D, Weinstein EJ, Choy E, Hornicek FJ, Wood KB, Liu X, Mankin H, Duan Z. PMID: 20042639.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    146. Doxorubicin loaded Polymeric Nanoparticulate Delivery System to overcome drug resistance in osteosarcoma. BMC Cancer. 2009 Nov 16; 9:399. Susa M, Iyer AK, Ryu K, Hornicek FJ, Mankin H, Amiji MM, Duan Z. PMID: 19917123.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    147. NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistance. PLoS One. 2009 Oct 12; 4(10):e7415. Duan Z, Choy E, Hornicek FJ. PMID: 19823672.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    148. ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines. PLoS One. 2009 Sep 09; 4(9):e6967. Duan Z, Choy E, Harmon D, Yang C, Ryu K, Schwab J, Mankin H, Hornicek FJ. PMID: 19742314.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    149. A novel target for treatment of chordoma: signal transducers and activators of transcription 3. . 2009 Sep; 8(9):2597-605. Yang C, Schwab JH, Schoenfeld AJ, Hornicek FJ, Wood KB, Nielsen GP, Choy E, Mankin H, Duan Z. PMID: 19723879.
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    150. Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines. . 2009 Aug; 8(8):2122-30. Duan Z, Choy E, Harmon D, Yang C, Ryu K, Schwab J, Mankin H, Hornicek FJ. PMID: 19638450.
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    151. Combination of PI3K/mTOR inhibition demonstrates efficacy in human chordoma. Anticancer Res. 2009 Jun; 29(6):1867-71. Schwab J, Antonescu C, Boland P, Healey J, Rosenberg A, Nielsen P, Iafrate J, Delaney T, Yoon S, Choy E, Harmon D, Raskin K, Yang C, Mankin H, Springfield D, Hornicek F, Duan Z. PMID: 19528441.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    152. RAIDD expression is impaired in multidrug resistant osteosarcoma cell lines. Cancer Chemother Pharmacol. 2009 Aug; 64(3):607-14. Yang C, Hornicek FJ, Wood KB, Schwab JH, Mankin H, Duan Z. PMID: 19125251.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    153. Multidrug resistant osteosarcoma cell lines exhibit deficiency of GADD45alpha expression. Apoptosis. 2009 Jan; 14(1):124-33. Yang C, Yang S, Wood KB, Hornicek FJ, Schwab JH, Fondren G, Mankin H, Duan Z. PMID: 19052873.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    154. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines. Cancer Chemother Pharmacol. 2009 May; 63(6):1121-9. Duan Z, Choy E, Jimeno JM, Cuevas Cdel M, Mankin HJ, Hornicek FJ. PMID: 18828019.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    155. Lentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer. . 2008 Aug; 7(8):2377-85. Duan Z, Weinstein EJ, Ji D, Ames RY, Choy E, Mankin H, Hornicek FJ. PMID: 18687998.
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    156. CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells. Cancer Chemother Pharmacol. 2009 Mar; 63(4):681-9. Duan Z, Ames RY, Ryan M, Hornicek FJ, Mankin H, Seiden MV. PMID: 18587580.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    157. Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles. Clin Cancer Res. 2008 May 15; 14(10):3193-203. Devalapally H, Duan Z, Seiden MV, Amiji MM. PMID: 18483388.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    158. Paclitaxel and ceramide co-administration in biodegradable polymeric nanoparticulate delivery system to overcome drug resistance in ovarian cancer. Int J Cancer. 2007 Oct 15; 121(8):1830-8. Devalapally H, Duan Z, Seiden MV, Amiji MM. PMID: 17557285.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    159. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells. Mol Pharmacol. 2007 Nov; 72(5):1137-45. Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV. PMID: 17675586.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    160. Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer. Cancer Res. 2007 May 15; 67(10):4843-50. van Vlerken LE, Duan Z, Seiden MV, Amiji MM. PMID: 17510414.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    161. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. Clin Cancer Res. 2006 Sep 01; 12(17):5055-63. Duan Z, Foster R, Bell DA, Mahoney J, Wolak K, Vaidya A, Hampel C, Lee H, Seiden MV. PMID: 16951221.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    162. MM-TRAG (MGC4175), a novel intracellular mitochondrial protein, is associated with the taxol- and doxorubicin-resistant phenotype in human cancer cell lines. Gene. 2004 Sep 29; 340(1):53-9. Duan Z, Brakora KA, Seiden MV. PMID: 15556294.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    163. Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells. . 2004 Jul; 3(7):833-8. Duan Z, Brakora KA, Seiden MV. PMID: 15252144.
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