Andrea J Rapkin

Title(s)Professor, Obstetrics and Gynecology
SchoolMedicine
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    Deriving Novel Biomarkers of Localized Provoked Vulvodynia through Metabolomics: A Biological System Based Approach
    NIH R21HD086737Aug 1, 2016 - Jul 31, 2019
    Role: Co-Principal Investigator
    PROFILING VULVODYNIA BASED ON NEUROBIOLOGICAL AND BEHAVIORAL ENDOPHENOTYPES
    NIH R01HD076756Sep 1, 2013 - May 31, 2020
    Role: Co-Principal Investigator
    Neural Substrates of Emotion Regulation in Premenstrual Dysphoric Disorder
    NIH R21MH098668May 1, 2013 - Apr 30, 2016
    Role: Co-Principal Investigator

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    1. Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe). Ann Med. 2022 12; 54(1):2885-2897. Carey ET, Geller EJ, Rapkin A, Farb D, Cutting H, Akaninwor J, Stirling C, Bortsov A, McNulty S, Merrill P, Zakroysky P, DeLaRosa J, Luo S, Nackley AG. PMID: 36269028; PMCID: PMC9624211.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    2. Symptom-associated alterations in functional connectivity in primary and secondary provoked vestibulodynia. Pain. 2023 03 01; 164(3):653-665. Oughourlian TC, Tun G, Antony KM, Gupta A, Mays VM, Mayer EA, Rapkin AJ, Labus JS. PMID: 35972459.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. A Review of Chronic Pelvic Pain in Women-Reply. JAMA. 2021 12 07; 326(21):2207-2208. Lamvu G, Ouyang C, Rapkin A. PMID: 34874421.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Chronic Pelvic Pain in Women: A Review. JAMA. 2021 Jun 15; 325(23):2381-2391. Lamvu G, Carrillo J, Ouyang C, Rapkin A. PMID: 34128995.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    5. Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia. J Pain. 2021 12; 22(12):1586-1605. Labus JS, Mayer EA, Tillisch K, Aagaard KM, Stains J, Broniowska K, Van Remortel C, Tun G, Rapkin A. PMID: 34029688; PMCID: PMC10460622.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Effects of oral contraceptive pills on mood and magnetic resonance imaging measures of prefrontal cortical thickness. Mol Psychiatry. 2021 03; 26(3):917-926. Petersen N, Kearley NW, Ghahremani DG, Pochon JB, Fry ME, Rapkin AJ, London ED. PMID: 33420480; PMCID: PMC7914152.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    7. Striatal dopamine D2-type receptor availability and peripheral 17β-estradiol. Mol Psychiatry. 2021 06; 26(6):2038-2047. Petersen N, Rapkin AJ, Okita K, Kinney KR, Mizuno T, Mandelkern MA, London ED. PMID: 33420479; PMCID: PMC9196143.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Reduced concentrations of vaginal metabolites involved in steroid hormone biosynthesis are associated with increased vulvar vestibular pain and vaginal muscle tenderness in provoked vestibulodynia: An exploratory metabolomics study. Mol Pain. 2021 Jan-Dec; 17:17448069211041853. Labus JS, Mayer EA, Aagaard K, Stains J, Broniowska K, Rapkin A. PMID: 34505814; PMCID: PMC8438271.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Ecological Momentary Assessment of Non-Menstrual Pelvic Pain: Potential Pathways of Central Sensitization in Adolescents and Young Adults with and without Primary Dysmenorrhea. J Pain Res. 2020; 13:3447-3456. Seidman LC, Temme CR, Zeltzer LK, Rapkin AJ, Naliboff BD, Payne LA. PMID: 33376390; PMCID: PMC7764911.
      View in: PubMed   Mentions: 2  
    10. Predictors of Mucosal and Muscle Pain in Vulvodynia: A Cross-Sectional Analysis From the National Vulvodynia Registry. J Pain. 2021 02; 22(2):161-170. Lo L, Lamvu G, Alappattu M, Witzeman K, Markovic D, Rapkin A. PMID: 32679255.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Effectiveness of transdermal nicotine patch in premenopausal female smokers is moderated by within-subject severity of negative affect and physical symptoms. Psychopharmacology (Berl). 2020 Jun; 237(6):1737-1744. Chai SH, Leventhal AM, Kirkpatrick MG, Eisenlohr-Moul TA, Rapkin AJ, D'Orazio L, Pang RD. PMID: 32157328; PMCID: PMC7244386.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Resting-state functional connectivity in women with PMDD. Transl Psychiatry. 2019 12 11; 9(1):339. Petersen N, Ghahremani DG, Rapkin AJ, Berman SM, Wijker N, Liang L, London ED. PMID: 31827073; PMCID: PMC6906514.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    13. Contraception counseling for women with premenstrual dysphoric disorder (PMDD): current perspectives. Open Access J Contracept. 2019; 10:27-39. Rapkin AJ, Korotkaya Y, Taylor KC. PMID: 31572029; PMCID: PMC6759213.
      View in: PubMed   Mentions: 13  
    14. Altered gray matter volume in sensorimotor and thalamic regions associated with pain in localized provoked vulvodynia: a voxel-based morphometry study. Pain. 2019 07; 160(7):1529-1540. Bhatt RR, Gupta A, Rapkin A, Kilpatrick LA, Hamadani K, Pazmany E, Van Oudenhove L, Stains J, Aerts L, Enzlin P, Tillisch K, Mayer EA, Labus JS. PMID: 30817440; PMCID: PMC6586504.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    15. Experimental evaluation of central pain processes in young women with primary dysmenorrhea. Pain. 2019 06; 160(6):1421-1430. Payne LA, Seidman LC, Sim MS, Rapkin AJ, Naliboff BD, Zeltzer LK. PMID: 30720583; PMCID: PMC6527468.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    16. Managing the risks of mood symptoms with LNG-IUS: a clinical perspective. Eur J Contracept Reprod Health Care. 2018 Oct; 23(5):321-325. Bitzer J, Rapkin A, Soares CN. PMID: 30468396.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Patterns in Vulvodynia Treatments and 6-Month Outcomes for Women Enrolled in the National Vulvodynia Registry-An Exploratory Prospective Study. J Sex Med. 2018 05; 15(5):705-715. Lamvu G, Alappattu M, Witzeman K, Bishop M, Robinson M, Rapkin A. PMID: 29631955; PMCID: PMC6613576.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Disease-Related Microstructural Differences in the Brain in Women With Provoked Vestibulodynia. J Pain. 2018 05; 19(5):528.e1-528.e15. Gupta A, Woodworth DC, Ellingson BM, Rapkin AJ, Naliboff B, Kilpatrick LA, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. PMID: 29391213; PMCID: PMC5927835.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Brain activation during emotion regulation in women with premenstrual dysphoric disorder. Psychol Med. 2018 08; 48(11):1795-1802. Petersen N, Ghahremani DG, Rapkin AJ, Berman SM, Liang L, London ED. PMID: 29145910; PMCID: PMC9196139.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    20. Rates of Anovulation in Adolescents and Young Adults with Moderate to Severe Primary Dysmenorrhea and Those without Primary Dysmenorrhea. J Pediatr Adolesc Gynecol. 2018 Apr; 31(2):94-101. Seidman LC, Brennan KM, Rapkin AJ, Payne LA. PMID: 29017868; PMCID: PMC5866740.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Experimental and procedural pain responses in primary dysmenorrhea: a systematic review. J Pain Res. 2017; 10:2233-2246. Payne LA, Rapkin AJ, Seidman LC, Zeltzer LK, Tsao JC. PMID: 29066929; PMCID: PMC5604431.
      View in: PubMed   Mentions: 16  
    22. Vulvodynia is not created equally: empirical classification of women with vulvodynia. J Pain Res. 2017; 10:1601-1609. Alappattu M, Lamvu G, Feranec J, Witzeman K, Robinson M, Rapkin A. PMID: 28740427; PMCID: PMC5505540.
      View in: PubMed   Mentions: 1  
    23. Catechol-O-methyltransferase gene polymorphism and vulvar pain in women with vulvodynia. Am J Obstet Gynecol. 2017 Apr; 216(4):395.e1-395.e6. Patanwala IY, Lamvu G, Ledger WJ, Witzeman K, Marvel R, Rapkin A, Bongiovanni AM, Feranec J, Witkin SS. PMID: 27780702.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Fourth consensus of the International Society for Premenstrual Disorders (ISPMD): auditable standards for diagnosis and management of premenstrual disorder. Arch Womens Ment Health. 2016 12; 19(6):953-958. Ismaili E, Walsh S, O'Brien PMS, Bäckström T, Brown C, Dennerstein L, Eriksson E, Freeman EW, Ismail KMK, Panay N, Pearlstein T, Rapkin A, Steiner M, Studd J, Sundström-Paromma I, Endicott J, Epperson CN, Halbreich U, Reid R, Rubinow D, Schmidt P, Yonkers K, Consensus Group of the International Society for Premenstrual Disorders. PMID: 27378473.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    25. Emotion regulation in women with premenstrual dysphoric disorder. Arch Womens Ment Health. 2016 10; 19(5):891-8. Petersen N, London ED, Liang L, Ghahremani DG, Gerards R, Goldman L, Rapkin AJ. PMID: 27155663; PMCID: PMC5024711.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    26. Pain Catastrophizing Predicts Menstrual Pain Ratings in Adolescent Girls with Chronic Pain. Pain Med. 2016 Jan; 17(1):16-24. Payne LA, Rapkin AJ, Lung KC, Seidman LC, Zeltzer LK, Tsao JC. PMID: 26218344; PMCID: PMC4791196.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    27. Vulvodynia: The Role of Inflammation in the Etiology of Localized Provoked Pain of the Vulvar Vestibule (Vestibulodynia). Semin Reprod Med. 2015 Jul; 33(4):239-45. Akopians AL, Rapkin AJ. PMID: 26132928.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    28. The Evidence-based Vulvodynia Assessment Project. A National Registry for the Study of Vulvodynia. J Reprod Med. 2015 May-Jun; 60(5-6):223-35. Lamvu G, Nguyen RH, Burrows LJ, Rapkin A, Witzeman K, Marvel RP, Hutchins D, Witkin SS, Veasley C, Fillingim R, Zolnoun D. PMID: 26126308.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May; 156(5):809-819. Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. PMID: 25735001; PMCID: PMC4402252.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    30. The Cerebellum and Premenstrual Dysphoric Disorder. AIMS Neurosci. 2014; 1(2):120-141. Rapkin AJ, Berman SM, London ED. PMID: 28275721; PMCID: PMC5338637.
      View in: PubMed   Mentions: 2  
    31. Treatment of premenstrual dysphoric disorder. Womens Health (Lond). 2013 Nov; 9(6):537-56. Rapkin AJ, Lewis EI. PMID: 24161307.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    32. Premenstrual dysphoric disorder and severe premenstrual syndrome in adolescents. Paediatr Drugs. 2013 Jun; 15(3):191-202. Rapkin AJ, Mikacich JA. PMID: 23529867.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    33. ISPMD consensus on the management of premenstrual disorders. Arch Womens Ment Health. 2013 Aug; 16(4):279-91. Nevatte T, O'Brien PM, Bäckström T, Brown C, Dennerstein L, Endicott J, Epperson CN, Eriksson E, Freeman EW, Halbreich U, Ismail K, Panay N, Pearlstein T, Rapkin A, Reid R, Rubinow D, Schmidt P, Steiner M, Studd J, Sundström-Poromaa I, Yonkers K, Consensus Group of the International Society for Premenstrual Disorders. PMID: 23624686; PMCID: PMC3955202.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    34. Clinical subtypes of core premenstrual disorders: a Delphi survey. Arch Womens Ment Health. 2013 Jun; 16(3):197-201. Ismail KM, Nevatte T, O'Brien S, Paschetta E, Bäckström T, Dennerstein L, Eriksson E, Freeman EW, Panay N, Pearlstein T, Rapkin A, Steiner M, Studd J, Sundström-Poromaa I. PMID: 23292120.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Multilevel local anesthetic nerve blockade for the treatment of generalized vulvodynia: a pilot study. J Sex Med. 2012 Nov; 9(11):2919-26. McDonald JS, Rapkin AJ. PMID: 22925528.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Elevated gray matter volume of the emotional cerebellum in women with premenstrual dysphoric disorder. J Affect Disord. 2013 Apr 05; 146(2):266-71. Berman SM, London ED, Morgan M, Rapkin AJ. PMID: 22868063; PMCID: PMC3529750.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder. Menopause Int. 2012 Jun; 18(2):52-9. Rapkin AJ, Akopians AL. PMID: 22611222.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    38. An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome. Contraception. 2012 May; 85(5):437-45. Freeman EW, Halbreich U, Grubb GS, Rapkin AJ, Skouby SO, Smith L, Mirkin S, Constantine GD. PMID: 22152588.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    39. Estradiol attenuates the adenosine triphosphate-induced increase of intracellular calcium through group II metabotropic glutamate receptors in rat dorsal root ganglion neurons. J Neurosci Res. 2011 Nov; 89(11):1707-10. Chaban V, Li J, McDonald JS, Rapkin A, Micevych P. PMID: 21793040; PMCID: PMC3171520.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    40. Continuous oral levonorgestrel/ethinyl estradiol for treating premenstrual dysphoric disorder. Contraception. 2012 Jan; 85(1):19-27. Halbreich U, Freeman EW, Rapkin AJ, Cohen LS, Grubb GS, Bergeron R, Smith L, Mirkin S, Constantine GD. PMID: 22067793.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    41. Diagnosis and management of premenstrual disorders. BMJ. 2011 Jun 03; 342:d2994. O'Brien S, Rapkin A, Dennerstein L, Nevatte T. PMID: 21642323.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    42. Ethinyl estradiol 20μg/drospirenone 3mg 24/4 oral contraceptive for the treatment of functional impairment in women with premenstrual dysphoric disorder. Int J Gynaecol Obstet. 2011 May; 113(2):103-7. Marr J, Heinemann K, Kunz M, Rapkin A. PMID: 21338987.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Towards a consensus on diagnostic criteria, measurement and trial design of the premenstrual disorders: the ISPMD Montreal consensus. Arch Womens Ment Health. 2011 Feb; 14(1):13-21. O'Brien PM, Bäckström T, Brown C, Dennerstein L, Endicott J, Epperson CN, Eriksson E, Freeman E, Halbreich U, Ismail KM, Panay N, Pearlstein T, Rapkin A, Reid R, Schmidt P, Steiner M, Studd J, Yonkers K. PMID: 21225438; PMCID: PMC4134928.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    44. Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorder. Biol Psychiatry. 2011 Feb 15; 69(4):374-80. Rapkin AJ, Berman SM, Mandelkern MA, Silverman DH, Morgan M, London ED. PMID: 21092938; PMCID: PMC3053132.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    45. Clitoral and vulvar vestibular sensation in women taking 20 mcg ethinyl estradiol combined oral contraceptives: a preliminary study. J Sex Med. 2011 Jan; 8(1):213-8. Lee M, Morgan M, Rapkin A. PMID: 20955310.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Treatment of metronidazole-resistant Trichomonas vaginalis. Sex Health. 2009 Dec; 6(4):345-7. Goldman LM, Upcroft JA, Workowski K, Rapkin A. PMID: 19917205.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    47. Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women. Arch Womens Ment Health. 2010 Feb; 13(1):91-8. Morgan ML, Rapkin AJ, Biggio G, Serra M, Pisu MG, Rasgon N. PMID: 19728035; PMCID: PMC2815799.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Premenstrual syndrome and premenstrual dysphoric disorder: quality of life and burden of illness. Expert Rev Pharmacoecon Outcomes Res. 2009 Apr; 9(2):157-70. Rapkin AJ, Winer SA. PMID: 19402804.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansPHPublic Health
    49. Premenstrual syndrome and premenstrual dysphoric disorder in adolescents. Curr Opin Obstet Gynecol. 2008 Oct; 20(5):455-63. Rapkin AJ, Mikacich JA. PMID: 18797268.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. Inflammation in the uterus induces phosphorylated extracellular signal-regulated kinase and substance P immunoreactivity in dorsal root ganglia neurons innervating both uterus and colon in rats. J Neurosci Res. 2008 Sep; 86(12):2746-52. Li J, Micevych P, McDonald J, Rapkin A, Chaban V. PMID: 18478547; PMCID: PMC4755493.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    51. YAZ in the treatment of premenstrual dysphoric disorder. J Reprod Med. 2008 Sep; 53(9 Suppl):729-41. Rapkin AJ. PMID: 18980045.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    52. The pharmacologic management of premenstrual dysphoric disorder. Expert Opin Pharmacother. 2008 Feb; 9(3):429-45. Rapkin AJ, Winer SA. PMID: 18220493.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. Drospirenone/ethinyl estradiol. Drugs Today (Barc). 2008 Feb; 44(2):133-45. Rapkin AJ, Sorger SN, Winer SA. PMID: 18389090.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    54. Multilevel local anesthetic nerve blockade for the treatment of vulvar vestibulitis syndrome. Am J Obstet Gynecol. 2008 Jan; 198(1):41.e1-5. Rapkin AJ, McDonald JS, Morgan M. PMID: 17936236.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    55. Ethinyl estradiol/drospirenone for the treatment of the emotional and physical symptoms of premenstrual dysphoric disorder. Womens Health (Lond). 2007 Jul; 3(4):395-408. Rapkin AJ, McDonald M, Winer SA. PMID: 19804014.
      View in: PubMed   Mentions: 1     Fields:    
    56. Drospirenone: a novel progestin. Expert Opin Pharmacother. 2007 May; 8(7):989-99. Rapkin AJ, Winer SA. PMID: 17472544.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    57. Clinical diagnostic criteria for premenstrual syndrome and guidelines for their quantification for research studies. Gynecol Endocrinol. 2007 Mar; 23(3):123-30. Halbreich U, Backstrom T, Eriksson E, O'brien S, Calil H, Ceskova E, Dennerstein L, Douki S, Freeman E, Genazzani A, Heuser I, Kadri N, Rapkin A, Steiner M, Wittchen HU, Yonkers K. PMID: 17454164.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    58. The same dorsal root ganglion neurons innervate uterus and colon in the rat. Neuroreport. 2007 Feb 12; 18(3):209-12. Chaban V, Christensen A, Wakamatsu M, McDonald M, Rapkin A, McDonald J, Micevych P. PMID: 17314658.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    59. Vasomotor symptoms in menopause: physiologic condition and central nervous system approaches to treatment. Am J Obstet Gynecol. 2007 Feb; 196(2):97-106. Rapkin AJ. PMID: 17306645.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    60. Oral contraceptives and neuroactive steroids. Pharmacol Biochem Behav. 2006 Aug; 84(4):628-34. Rapkin AJ, Biggio G, Concas A. PMID: 16854457.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    61. Neurophysiologic changes during estrogen augmentation in perimenopausal depression. Maturitas. 2007 Jan 20; 56(1):54-60. Morgan ML, Cook IA, Rapkin AJ, Leuchter AF. PMID: 16835012.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    62. Relationships among self-rated tanner staging, hormones, and psychosocial factors in healthy female adolescents. J Pediatr Adolesc Gynecol. 2006 Jun; 19(3):181-7. Rapkin AJ, Tsao JC, Turk N, Anderson M, Zeltzer LK. PMID: 16731411.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    63. Estrogen and response to sertraline in postmenopausal women with major depressive disorder: a pilot study. J Psychiatr Res. 2007 Apr-Jun; 41(3-4):338-43. Rasgon NL, Dunkin J, Fairbanks L, Altshuler LL, Troung C, Elman S, Wroolie TE, Brunhuber MV, Rapkin A. PMID: 16697413.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    64. Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changes. Fertil Steril. 2006 May; 85(5):1371-8. Rapkin AJ, Morgan M, Sogliano C, Biggio G, Concas A. PMID: 16580672.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    65. Premenstrual disorders: prevalence, etiology and impact. J Reprod Med. 2006 Apr; 51(4 Suppl):339-47. Winer SA, Rapkin AJ. PMID: 16734317.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    66. Diagnosis of premenstrual disorders. J Reprod Med. 2006 Apr; 51(4 Suppl):349-58. Futterman LA, Rapkin AJ. PMID: 16734318.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    67. Treatment of premenstrual disorders. J Reprod Med. 2006 Apr; 51(4 Suppl):359-70. Kroll R, Rapkin AJ. PMID: 16734319.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    68. Premenstrual syndrome in adolescents: diagnosis and treatment. Pediatr Endocrinol Rev. 2006 Jan; 3 Suppl 1:132-7. Rapkin AJ, Mikacich JA. PMID: 16641847.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    69. New treatment approaches for premenstrual disorders. Am J Manag Care. 2005 Dec; 11(16 Suppl):S480-91. Rapkin AJ. PMID: 16336057.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    70. Efficacy of a new low-dose oral contraceptive with drospirenone in premenstrual dysphoric disorder. Obstet Gynecol. 2005 Sep; 106(3):492-501. Yonkers KA, Brown C, Pearlstein TB, Foegh M, Sampson-Landers C, Rapkin A. PMID: 16135578.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCTClinical Trials
    71. The pains of endometriosis. Science. 2005 Jun 10; 308(5728):1587-9. Berkley KJ, Rapkin AJ, Papka RE. PMID: 15947176.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    72. Estrogen augmentation of antidepressants in perimenopausal depression: a pilot study. J Clin Psychiatry. 2005 Jun; 66(6):774-80. Morgan ML, Cook IA, Rapkin AJ, Leuchter AF. PMID: 15960574.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    73. Reproductive events modify the effects of estrogen replacement therapy on cognition in healthy postmenopausal women. Psychoneuroendocrinology. 2005 Apr; 30(3):284-96. Dunkin J, Rasgon N, Wagner-Steh K, David S, Altshuler L, Rapkin A. PMID: 15511602.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    74. Gynecological health of females with congenital heart disease. Int J Cardiol. 2005 Feb 28; 98(3):379-87. Canobbio MM, Perloff JK, Rapkin AJ. PMID: 15708168.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    75. A review of treatment of premenstrual syndrome and premenstrual dysphoric disorder. Psychoneuroendocrinology. 2003 Aug; 28 Suppl 3:39-53. Rapkin A. PMID: 12892989.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    76. Effect of an oral contraceptive containing ethinyl estradiol and drospirenone on premenstrual symptomatology and health-related quality of life. J Reprod Med. 2003 Feb; 48(2):79-85. Borenstein J, Yu HT, Wade S, Chiou CF, Rapkin A. PMID: 12621790.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    77. The clinical nature and formal diagnosis of premenstrual, postpartum, and perimenopausal affective disorders. Curr Psychiatry Rep. 2002 Dec; 4(6):419-28. Rapkin AJ, Mikacich JA, Moatakef-Imani B, Rasgon N. PMID: 12441021.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    78. Cognitive flexibility, reaction time, and attention in women with premenstrual dysphoric disorder. J Gend Specif Med. 2002 May-Jun; 5(3):28-36. Morgan M, Rapkin A. PMID: 12078060.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    79. Estrogen replacement therapy in the treatment of major depressive disorder in perimenopausal women. J Clin Psychiatry. 2002; 63 Suppl 7:45-8. Rasgon NL, Altshuler LL, Fairbanks LA, Dunkin JJ, Davtyan C, Elman S, Rapkin AJ. PMID: 11995778.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCTClinical Trials
    80. Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndrome. Eur J Endocrinol. 2001 Jul; 145(1):25-33. Rasgon N, Serra M, Biggio G, Pisu MG, Fairbanks L, Tanavoli S, Rapkin A. PMID: 11415849.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    81. Evaluation of a unique oral contraceptive in the treatment of premenstrual dysphoric disorder. J Womens Health Gend Based Med. 2001 Jul-Aug; 10(6):561-9. Freeman EW, Kroll R, Rapkin A, Pearlstein T, Brown C, Parsey K, Zhang P, Patel H, Foegh M, PMS/PMDD Research Group. PMID: 11559453.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCTClinical Trials
    82. Menstrual cycle-related brain metabolite changes using 1H magnetic resonance spectroscopy in premenopausal women: a pilot study. Psychiatry Res. 2001 Feb 28; 106(1):47-57. Rasgon NL, Thomas MA, Guze BH, Fairbanks LA, Yue K, Curran JG, Rapkin AJ. PMID: 11231099.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    83. Peritoneal fluid interleukin-6 in women with chronic pelvic pain. Fertil Steril. 2000 Aug; 74(2):325-8. Rapkin A, Morgan M, Bonpane C, Martinez-Maza O. PMID: 10927052.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    84. Neuroendocrine response to an intravenous L-tryptophan challenge in women with premenstrual syndrome. Fertil Steril. 2000 Jan; 73(1):144-9. Rasgon N, McGuire M, Tanavoli S, Fairbanks L, Rapkin A. PMID: 10632430.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    85. Insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 in women with premenstrual syndrome. Fertil Steril. 1998 Dec; 70(6):1077-80. Rapkin AJ, Cedars M, Morgan M, Goldman L. PMID: 9848298.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    86. Progesterone metabolite allopregnanolone in women with premenstrual syndrome. Obstet Gynecol. 1997 Nov; 90(5):709-14. Rapkin AJ, Morgan M, Goldman L, Brann DW, Simone D, Mahesh VB. PMID: 9351749.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    87. Cognitive functioning in premenstrual syndrome. Obstet Gynecol. 1996 Dec; 88(6):961-6. Morgan M, Rapkin AJ, D'Elia L, Reading A, Goldman L. PMID: 8942835.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    88. Decreased central opioid activity in premenstrual syndrome: luteinizing hormone response to naloxone. J Soc Gynecol Investig. 1996 Mar-Apr; 3(2):93-8. Rapkin AJ, Shoupe D, Reading A, Daneshgar KK, Goldman L, Bohn Y, Brann DW, Mahesh VB. PMID: 8796815.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    89. Menstrual patterns in women with congenital heart disease. Pediatr Cardiol. 1995 Jan-Feb; 16(1):12-5. Canobbio MM, Rapkin AJ, Perloff JK, Lin A, Child JS. PMID: 7753694.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    90. Menstrual cycle and social behavior in vervet monkeys. Psychoneuroendocrinology. 1995; 20(3):289-97. Rapkin AJ, Pollack DB, Raleigh MJ, Stone B, McGuire MT. PMID: 7777657.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    91. Gastroenterologic causes of chronic pelvic pain. Obstet Gynecol Clin North Am. 1993 Dec; 20(4):663-83. Rapkin AJ, Mayer EA. PMID: 8115083.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    92. Tryptophan and neutral amino acids in premenstrual syndrome. Am J Obstet Gynecol. 1991 Dec; 165(6 Pt 1):1830-3. Rapkin AJ, Reading AE, Woo S, Goldman LM. PMID: 1750482.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    93. Menstrual patterns in females after the Fontan repair. Am J Cardiol. 1990 Jul 15; 66(2):238-40. Canobbio MM, Mair DD, Rapkin AJ, Perloff JK, George BL. PMID: 2371960.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    94. History of physical and sexual abuse in women with chronic pelvic pain. Obstet Gynecol. 1990 Jul; 76(1):92-6. Rapkin AJ, Kames LD, Darke LL, Stampler FM, Naliboff BD. PMID: 2359571.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    95. Effectiveness of an interdisciplinary pain management program for the treatment of chronic pelvic pain. Pain. 1990 Apr; 41(1):41-46. Kames LD, Rapkin AJ, Naliboff BD, Afifi S, Ferrer-Brechner T. PMID: 2352765.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    96. Mood and cognitive style in premenstrual syndrome. Obstet Gynecol. 1989 Oct; 74(4):644-9. Rapkin AJ, Chang LC, Reading AE. PMID: 2797641.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    97. Peritoneal fluid eicosanoids in chronic pelvic pain. Prostaglandins. 1989 Oct; 38(4):447-52. Rapkin A, Bhattacherjee P. PMID: 2554365.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    98. Platelet monoamine oxidase B activity in women with premenstrual syndrome. Am J Obstet Gynecol. 1988 Dec; 159(6):1536-40. Rapkin AJ, Buckman TD, Sutphin MS, Chang LC, Reading AE. PMID: 3207130.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    99. Non-availability of the IUD and contraceptive choice. Contraception. 1988 Apr; 37(4):383-90. Rapkin AJ, Alcalay R, Mitchell J. PMID: 3383575.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    100. Whole-blood serotonin in premenstrual syndrome. Obstet Gynecol. 1987 Oct; 70(4):533-7. Rapkin AJ, Edelmuth E, Chang LC, Reading AE, McGuire MT, Su TP. PMID: 3627623.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    101. The pain management approach to chronic pelvic pain. J Reprod Med. 1987 May; 32(5):323-7. Rapkin AJ, Kames LD. PMID: 2439689.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    102. Adhesions and pelvic pain: a retrospective study. Obstet Gynecol. 1986 Jul; 68(1):13-5. Rapkin AJ. PMID: 2941707.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
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