Diego Gelsinger

Title(s)Assistant Professor, Human Genetics
SchoolMedicine
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    Title(s)Assistant Professor, Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Toward precision microbiome therapeutics: From black box to blueprint. Cell Host Microbe. 2026 Jul 08; 34(7):1157-1161. Gelsinger DR, Wang HH. PMID: 42419262.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases. Science. 2025 Nov 13; 390(6774):eadx7604. Gelsinger DR, Ronda C, Ma J, Kar OB, Edwards M, Huang Y, Mavros CF, Sun Y, Perdue T, Vo PL, Ivanov II, Sternberg SH, Wang HH. PMID: 41231980; PMCID: PMC12969935.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    3. Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase. Science. 2025 05 15; 388(6748):eadt5199. Witte IP, Lampe GD, Eitzinger S, Miller SM, Berríos KN, McElroy AN, King RT, Stringham OG, Gelsinger DR, Vo PLH, Chen AT, Tolar J, Osborn MJ, Sternberg SH, Liu DR. PMID: 40373119; PMCID: PMC12326709.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    4. Antagonistic conflict between transposon-encoded introns and guide RNAs. Science. 2024 07 12; 385(6705):eadm8189. Žedaveinyte R, Meers C, Le HC, Mortman EE, Tang S, Lampe GD, Pesari SR, Gelsinger DR, Wiegand T, Sternberg SH. PMID: 38991068; PMCID: PMC11758368.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    5. High-throughput transcriptomics of 409 bacteria-drug pairs reveals drivers of gut microbiota perturbation. Nat Microbiol. 2024 02; 9(2):561-575. Ricaurte D, Huang Y, Sheth RU, Gelsinger DR, Kaufman A, Wang HH. PMID: 38233648; PMCID: PMC11287798.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    6. Bacterial genome engineering using CRISPR-associated transposases. Nat Protoc. 2024 03; 19(3):752-790. Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang HH, Sternberg SH. PMID: 38216671; PMCID: PMC11702153.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    7. Antagonistic conflict between transposon-encoded introns and guide RNAs. bioRxiv. 2023 Nov 20. Žedaveinyte R, Meers C, Le HC, Mortman EE, Tang S, Lampe GD, Pesari SR, Gelsinger DR, Wiegand T, Sternberg SH. PMID: 38045383; PMCID: PMC10690162.
      View in: PubMed   Mentions:
    8. Bacterial genome engineering using CRISPR RNA-guided transposases. bioRxiv. 2023 Mar 21. Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang H, Sternberg SH. PMID: 36993567; PMCID: PMC10055292.
      View in: PubMed   Mentions:
    9. Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature. 2022 09; 609(7926):384-393. Hoffmann FT, Kim M, Beh LY, Wang J, Vo PLH, Gelsinger DR, George JT, Acree C, Mohabir JT, Fernández IS, Sternberg SH. PMID: 36002573; PMCID: PMC10583602.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    10. Conversion of Ribosome-Protected mRNA to DNA and Deep Sequencing for Ribosome Profiling in Haloferax volcanii. Methods Mol Biol. 2022; 2522:223-242. Gelsinger DR, Dallon E, DiRuggiero J. PMID: 36125753.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    11. Small RNA-Sequencing Library Preparation for the Halophilic Archaeon Haloferax volcanii. Methods Mol Biol. 2022; 2522:243-254. Gelsinger DR, DiRuggiero J. PMID: 36125754.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    12. Post-transcriptional regulation of redox homeostasis by the small RNA SHOxi in haloarchaea. RNA Biol. 2021 11; 18(11):1867-1881. Gelsinger DR, Reddy R, Whittington K, Debic S, DiRuggiero J. PMID: 33522404; PMCID: PMC8583180.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    13. Environmental Factors Driving Spatial Heterogeneity in Desert Halophile Microbial Communities. Front Microbiol. 2020; 11:578669. Uritskiy G, Munn A, Dailey M, Gelsinger DR, Getsin S, Davila A, McCullough PR, Taylor J, DiRuggiero J. PMID: 33193201; PMCID: PMC7606970.
      View in: PubMed   Mentions: 11  
    14. Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution. Nucleic Acids Res. 2020 06 04; 48(10):5201-5216. Gelsinger DR, Dallon E, Reddy R, Mohammad F, Buskirk AR, DiRuggiero J. PMID: 32382758; PMCID: PMC7261190.
      View in: PubMed   Mentions: 48     Fields:    Translation:Cells
    15. Cellular life from the three domains and viruses are transcriptionally active in a hypersaline desert community. Environ Microbiol. 2021 07; 23(7):3401-3417. Uritskiy G, Tisza MJ, Gelsinger DR, Munn A, Taylor J, DiRuggiero J. PMID: 32307861.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    16. Regulatory Noncoding Small RNAs Are Diverse and Abundant in an Extremophilic Microbial Community. mSystems. 2020 Feb 04; 5(1). Gelsinger DR, Uritskiy G, Reddy R, Munn A, Farney K, DiRuggiero J. PMID: 32019831; PMCID: PMC7002113.
      View in: PubMed   Mentions: 6     Fields:    
    17. Transcriptional Landscape and Regulatory Roles of Small Noncoding RNAs in the Oxidative Stress Response of the Haloarchaeon Haloferax volcanii. J Bacteriol. 2018 05 01; 200(9). Gelsinger DR, DiRuggiero J. PMID: 29463600; PMCID: PMC5892119.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    18. The Non-Coding Regulatory RNA Revolution in Archaea. Genes (Basel). 2018 Mar 05; 9(3). Gelsinger DR, DiRuggiero J. PMID: 29510582; PMCID: PMC5867862.
      View in: PubMed   Mentions: 25     Fields:    
    19. Functional interactions of archaea, bacteria and viruses in a hypersaline endolithic community. Environ Microbiol. 2016 06; 18(6):2064-77. Crits-Christoph A, Gelsinger DR, Ma B, Wierzchos J, Ravel J, Davila A, Casero MC, DiRuggiero J. PMID: 26914534.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    20. Near-peer STEM Mentoring Offers Unexpected Benefits for Mentors from Traditionally Underrepresented Backgrounds. Perspect Undergrad Res Mentor. 2015; 4(1). Trujillo G, Aguinaldo PG, Anderson C, Bustamante J, Gelsinger DR, Pastor MJ, Wright J, Márquez-Magaña L, Riggs B. PMID: 27668127; PMCID: PMC5034940.
      View in: PubMed   Mentions: 17  
    21. In situ metabolism in halite endolithic microbial communities of the hyperarid Atacama Desert. Front Microbiol. 2015; 6:1035. Davila AF, Hawes I, Araya JG, Gelsinger DR, DiRuggiero J, Ascaso C, Osano A, Wierzchos J. PMID: 26500612; PMCID: PMC4594028.
      View in: PubMed   Mentions: 18  
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