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Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages. Cell Rep. 2024 Aug 01; 43(8):114570.
Bourner LA, Chung LA, Long H, McGettrick AF, Xiao J, Roth K, Bailey JD, Strickland M, Tan B, Cunningham J, Lutzke B, McGee J, Otero FJ, Gemperline DC, Zhang L, Wang YC, Chalmers MJ, Yang CW, Gutierrez JA, O'Neill LAJ, Dorsey FC. PMID: 39093697.
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HumansCells
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SHIP1 modulation and proteome characterization of microglia. J Proteomics. 2024 Jun 30; 302:105198.
Ahat E, Shi Z, Chu S, Bui HH, Mason ER, Soni DM, Roth KD, Chalmers MJ, Oblak AL, Zhang J, Gutierrez JA, Richardson T. PMID: 38777089.
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HumansAnimalsCells
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Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC-MS. Bioanalysis. 2016 Aug; 8(15):1579-1595.
Cox JM, Berna MJ, Jin Z, Cox AL, Sloop KW, Gutierrez JA, Ackermann BL. PMID: 27314304.
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3 Fields:
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HumansAnimals
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Circulating FGF21 proteolytic processing mediated by fibroblast activation protein. Biochem J. 2016 Mar 01; 473(5):605-14.
Zhen EY, Jin Z, Ackermann BL, Thomas MK, Gutierrez JA. PMID: 26635356; PMCID: PMC4764976.
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PubMed Mentions:
59 Fields:
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HumansAnimalsCells
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A quantitative tool to distinguish isobaric leucine and isoleucine residues for mass spectrometry-based de novo monoclonal antibody sequencing. J Am Soc Mass Spectrom. 2014 Jul; 25(7):1228-36.
Poston CN, Higgs RE, You J, Gelfanova V, Hale JE, Knierman MD, Siegel R, Gutierrez JA. PMID: 24845350.
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6 Fields:
Translation:
Cells
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Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma. Anal Biochem. 2013 Nov 01; 442(1):1-9.
Zhen EY, Higgs RE, Gutierrez JA. PMID: 23872001.
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53 Fields:
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Humans
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Phosphotyrosine profiling of NSCLC cells in response to EGF and HGF reveals network specific mediators of invasion. J Proteome Res. 2013 Apr 05; 12(4):1856-67.
Johnson H, Lescarbeau RS, Gutierrez JA, White FM. PMID: 23438512; PMCID: PMC3950895.
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16 Fields:
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HumansCells
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The effects of vertical sleeve gastrectomy in rodents are ghrelin independent. Gastroenterology. 2013 Jan; 144(1):50-52.e5.
Chambers AP, Kirchner H, Wilson-Perez HE, Willency JA, Hale JE, Gaylinn BD, Thorner MO, Pfluger PT, Gutierrez JA, Tschöp MH, Sandoval DA, Seeley RJ. PMID: 22995675; PMCID: PMC3752595.
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PubMed Mentions:
74 Fields:
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AnimalsCells
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From ghrelin to ghrelin's O-acyl transferase. Methods Enzymol. 2012; 514:129-46.
Gutierrez JA, Willency JA, Knierman MD, Coskun T, Solenberg PJ, Perkins DR, Higgs RE, Hale JE. PMID: 22975051.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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GOAT links dietary lipids with the endocrine control of energy balance. Nat Med. 2009 Jul; 15(7):741-5.
Kirchner H, Gutierrez JA, Solenberg PJ, Pfluger PT, Czyzyk TA, Willency JA, Schürmann A, Joost HG, Jandacek RJ, Hale JE, Heiman ML, Tschöp MH. PMID: 19503064; PMCID: PMC2789701.
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143 Fields:
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AnimalsCells
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Ghrelin octanoylation mediated by an orphan lipid transferase. Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17):6320-5.
Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE, Hale JE. PMID: 18443287; PMCID: PMC2359796.
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PubMed Mentions:
292 Fields:
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HumansAnimalsCells
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In vitro and in vivo characterization of p-amino-phenethyl-m-trifluoromethylphenyl piperazine (PAPP), a novel serotonergic agonist with anthelmintic activity against Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis. Vet Parasitol. 2007 May 15; 146(1-2):58-65.
White WH, Gutierrez JA, Naylor SA, Cook CA, Gonzalez IC, Wisehart MA, Smith CK, Thompson WA. PMID: 17383823.
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PubMed Mentions:
5 Fields:
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AnimalsCells
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An in vivo rodent model for identifying and characterizing acaricides. J Med Entomol. 2006 May; 43(3):526-32.
Gutierrez JA, Zhao X, Kemper CJ, Plummer PR, Bauer SM, Hutchens DE, Smith CK, White WH. PMID: 16739411.
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Animals
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Quantitative determination of peptides using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Biotechniques. 2005 Jun; Suppl:13-7.
Gutierrez JA, Dorocke JA, Knierman MD, Gelfanova V, Higgs RE, Koh NL, Hale JE. PMID: 16528911.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Comparison of in vitro and in vivo ectoparasiticide activity of experimental benzimidazole-carbamate with permethrin and amitraz. J Med Entomol. 2005 Mar; 42(2):207-11.
White WH, Bauer SM, Zhao X, Gutierrez JA, Smith CK. PMID: 15799532.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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An in vitro larval immersion microassay for identifying and characterizing candidate acaricides. J Med Entomol. 2004 Nov; 41(6):1034-42.
White WH, Plummer PR, Kemper CJ, Miller RJ, Davey RB, Kemp DH, Hughes S, Smith CK, Gutierrez JA. PMID: 15605642.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsPHPublic Health
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Characterization of a novel G-protein coupled receptor from the parasitic nematode H. contortus with high affinity for serotonin. J Neurochem. 2003 Jul; 86(1):255-66.
Smith MW, Borts TL, Emkey R, Cook CA, Wiggins CJ, Gutierrez JA. PMID: 12807445.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells