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Michael Gilhooley

Title(s)HS Clinical Instructor, Ophthalmology
SchoolMedicine
ORCID ORCID Icon0000-0003-4109-5336 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Cambridge, CambridgeMBBChir (MD)06/2010Clinical Medicine
    Royal College of Ophthalmologists, LondonFRCOphth06/2016Ophthalmology
    University of Oxford, OxfordPhD01/2020Ophthalmology
    Moorfields Eye Hospital, LondonClinical Residency12/2022Ophthalmology
    Moorfields Eye Hospital, LondonClinical Fellowship12/2023Adult Strabismus
    University of Colorado, AuroraClinical Fellowship12/2024Neuro-ophthalmology
    University of Cambridge, CambridgeBA06/2007Neuroscience
    Collapse awards and honors
    North American Neuro-ophthalmology Society (NANOS) 2025Carlow Young Investigator Award
    Frost Trust2024Frost Trust Traveling Fellowship
    Royal Society of Medicine2024Ellison-Cliffe Traveling Fellowship
    University College London, Caius College2023The Berkely Fellowship
    North American Neuro-ophthalmology Society (NANOS)2021Best Abstract Award
    North American Neuro-ophthalmology Society (NANOS)2019Best Abstract Award
    United Kingdom Neuro-ophthalmology Society (UKNOS)2018Ivor Levy Award
    British and Irish Paediatric Ophthalmology and Strabismus Association2024David Laws Fellowship

    Collapse Overview 
    Collapse overview
    Dr. Michael J Gilhooley is a surgeon-scientist specializing in neuro-ophthalmology and adult strabismus. His research centers on the intrinsically photosensitive retinal ganglion cells of the optic nerve (ipRGCs) and the fascinating protein that renders them sensitive to light (melanopsin). His group is particularly interested in defining the mechanisms by which ipRGCs survive in inherited optic neuropathies while most other optic nerve cells die, leading to loss of vision. Uncovering why these rare cells are so resilient to disease is essential to develop novel treatments to protect sight in patients with optic nerve disease.
    The Gilhooley lab is always looking for enthusiastic students, post-doctoral scientists and others – please do not hesitate to be in touch.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interaction between native and prosthetic visual responses in optogenetic visual restoration. JCI Insight. 2025 Jun 09; 10(11). Carpentiero E, Hughes S, Rodgers J, Xhaferri N, Biswas S, Gilhooley MJ, Hankins MW, Lindner M. PMID: 40232851; PMCID: PMC12220941.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Inherited Optic Neuropathies: Real-World Experience in the Paediatric Neuro-Ophthalmology Clinic. Genes (Basel). 2024 01 30; 15(2). Gilhooley MJ, Raoof N, Yu-Wai-Man P, Moosajee M. PMID: 38397177; PMCID: PMC10888158.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium. Mol Neurodegener. 2023 09 21; 18(1):64. Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J, RReSTORe Consortium, Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Welsbie D, Zack DJ, Johnson TV. PMID: 37735444; PMCID: PMC10514988.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    4. Mitochondria and the eye-manifestations of mitochondrial diseases and their management. Eye (Lond). 2023 08; 37(12):2416-2425. Chen BS, Harvey JP, Gilhooley MJ, Jurkute N, Yu-Wai-Man P. PMID: 37185957; PMCID: PMC10397317.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    5. OPA1 Dominant Optic Atrophy: Pathogenesis and Therapeutic Targets. J Neuroophthalmol. 2023 12 01; 43(4):464-474. Wong DCS, Harvey JP, Jurkute N, Thomasy SM, Moosajee M, Yu-Wai-Man P, Gilhooley MJ. PMID: 37974363; PMCID: PMC10645107.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    6. Optogenetics for visual restoration: From proof of principle to translational challenges. Prog Retin Eye Res. 2022 11; 91:101089. Lindner M, Gilhooley MJ, Hughes S, Hankins MW. PMID: 35691861.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    7. A systematic comparison of optogenetic approaches to visual restoration. Mol Ther Methods Clin Dev. 2022 Jun 09; 25:111-123. Gilhooley MJ, Lindner M, Palumaa T, Hughes S, Peirson SN, Hankins MW. PMID: 35402632; PMCID: PMC8956963.
      View in: PubMed   Mentions: 13  
    8. Pembrolizumab for the treatment of progressive multifocal leukoencephalopathy following anti-CD19 CAR-T therapy: a case report. EJHaem. 2021 Nov; 2(4):848-853. Mackenzie S, Shafat M, Roddy H, Hyare H, Neill L, Marzolini MAV, Gilhooley M, Marafioti T, Kara E, Sanchez E, Rees J, Lynch DS, Thomson K, Ardeshna KM, Laurence A, Peggs KS, O'Reilly M, Roddie C. PMID: 35845220; PMCID: PMC9281485.
      View in: PubMed   Mentions: 7  
    9. ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration. Exp Eye Res. 2021 06; 207:108553. Gilhooley MJ, Hickey DG, Lindner M, Palumaa T, Hughes S, Peirson SN, MacLaren RE, Hankins MW. PMID: 33811915; PMCID: PMC8214074.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    10. From Transcriptomics to Treatment in Inherited Optic Neuropathies. Genes (Basel). 2021 01 22; 12(2). Gilhooley MJ, Owen N, Moosajee M, Yu Wai Man P. PMID: 33499292; PMCID: PMC7912133.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    11. "Genetic and clinical findings in an ethnically diverse retinitis pigmentosa cohort associated with pathogenic variants in EYS". Eye (Lond). 2021 May; 35(5):1440-1449. Cundy O, Broadgate S, Halford S, MacLaren RE, Shanks ME, Clouston P, Gilhooley MJ, Downes SM. PMID: 32728228; PMCID: PMC8182807.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. The functional characteristics of optogenetic gene therapy for vision restoration. Cell Mol Life Sci. 2021 Feb; 78(4):1597-1613. Lindner M, Gilhooley MJ, Peirson SN, Hughes S, Hankins MW. PMID: 32728765; PMCID: PMC7904736.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    13. Expression and Localization of Kcne2 in the Vertebrate Retina. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):33. Lindner M, Gilhooley MJ, Palumaa T, Morton AJ, Hughes S, Hankins MW. PMID: 32191288; PMCID: PMC7401445.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    14. Artificial vision: principles and prospects. Curr Opin Neurol. 2017 02; 30(1):55-60. Gilhooley MJ, Acheson J. PMID: 27984304.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. Idiopathic Acquired Temporal Wedge Visual Field Defects. Neuroophthalmology. 2016 Aug; 40(4):157-164. Gilhooley MJ, Fraser CL, Wong S, Hickman SJ, Plant GT. PMID: 27928401; PMCID: PMC5122908.
      View in: PubMed   Mentions: 1  
    16. Acute intermittent porphyria leading to posterior reversible encephalopathy syndrome (PRES): a rare cause of abdominal pain and seizures. BMJ Case Rep. 2016 Jun 08; 2016. Dagens A, Gilhooley MJ. PMID: 27277587; PMCID: PMC4904389.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Recurrent presumed herpes simplex keratitis and episcleritis in keratosis follicularis (Darier's disease). BMJ Case Rep. 2015 Jul 16; 2015. Radia M, Gilhooley MJ, Panos C, Claoué C. PMID: 26184361; PMCID: PMC4513587.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Using non-steroidal anti-inflammatory drugs in the treatment of depression. Psychiatr Danub. 2010 Nov; 22 Suppl 1:S49-52. Davis A, Gilhooley M, Agius M. PMID: 21057403.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Adult neurogenesis and depression: an introduction. Psychiatr Danub. 2010 Nov; 22 Suppl 1:S85-7. Gilhooley MJ. PMID: 21057409.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    20. What do large scale studies of medication in schizophrenia add to our management strategies? Psychiatr Danub. 2010 Jun; 22(2):323-8. Agius M, Davis A, Gilhooley M, Chapman S, Zaman R. PMID: 20562774.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Suicide risk and choice of antidepressant. Psychiatr Danub. 2010 Jun; 22(2):358-9. Davis A, Gilhooley M, Agius M, Zaman R. PMID: 20562782.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
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