Sindhu Chandran

Title(s)HS Clinical Professor, Medicine
SchoolMedicine
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    1. Regulatory T cell modulation with selective CD28 blockade and IL-6 receptor antagonist in kidney transplant recipients: results of CTOT-24, a prospective clinical trial. Am J Transplant. 2026 Jul 22. Chandran S, Tang Q, Leung JC, Armstrong BD, Friedewald JJ, Kirk AD, Laszik ZG, Goldstein J, Morsheimer M, Vincenti FG. PMID: 42486389.
      View in: PubMed   Mentions:    Fields:    
    2. Consensus-based Recommendations on the Management of Immunosuppression After Squamous Cell Carcinoma Diagnosis in Kidney Transplant Recipients: An International Delphi Consensus Statement. Transplant Direct. 2026 Jan; 12(1):e1893. Whitley MJ, Wang JX, Chapman J, de Vries APJ, Chandran S, Glennon CM, Madariaga HM, Carroll RP, Booth J, Concepcion B, Couzi L, De Serres SA, Doyle A, Forbes S, Gleadle JM, Griffin S, Gunaratnam L, Gupta G, Ho J, Hughes P, Isbel N, Jegatheesan DK, Jones G, Kuypers D, Lee B, Lim W, Mason P, Meneghini M, Owoyemi I, Rao S, Salama A, Sharif A, Thaunat O, Thuraisingham R, Wyburn K, Yabu JM, Jambusaria-Pahlajani A, Bottomley MJ, Arron ST. PMID: 41415033; PMCID: PMC12711373.
      View in: PubMed   Mentions: 1  
    3. Pharmacokinetics, lineage identity, and trafficking of ex vivo expanded polyclonal regulatory T cells in a prospective randomized clinical trial of kidney transplant recipients with allograft inflammation. Am J Transplant. 2026 Apr; 26(4):744-759. Chandran S, Leung JC, Vu A, Lee K, Fitch M, Esensten JH, Shy BR, Putnam AL, Lares A, Acevedo LA, Nguyen V, Liu W, Armstrong B, Laszik ZG, Mannon RB, Friedewald JJ, Naik A, Davis S, Sarwal M, Hellerstein M, Morsheimer M, Goldstein J, Tang Q, Vincenti FG. PMID: 41314617; PMCID: PMC12971219.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Interstitial Fibrosis in Kidney Allografts: Know Thy Enemy. Kidney Int Rep. 2025 Jul; 10(7):2107-2109. Chandran S, Prasad P. PMID: 40677354; PMCID: PMC12266281.
      View in: PubMed   Mentions:
    5. Donor-specific mesenchymal stem cell infusion in human and nonhuman primate kidney transplantation. Am J Transplant. 2025 Oct; 25(10):2114-2126. Anwar IJ, Li S, Mulvihill M, Schmitz R, Shaw B, Gao Q, Swan-Nesbit S, Cheatham LA, How T, Miller A, Williams K, Yin FF, Giles W, Kurtzberg J, Chandran S, Bridges N, Lyakh L, Breeden C, Gandhi K, Sever M, Song M, He X, Kirk AD. PMID: 40368061; PMCID: PMC12354185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Efficacy of Steroid Pulse to Treat Borderline T-Cell Mediated Rejection on Protocol Kidney Allograft Biopsy. Clin Transplant. 2025 May; 39(5):e70171. Kirn G, Chandran S, Rajalingam R, Feng S. PMID: 40329132.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study. Am J Transplant. 2025 May; 25(5):1030-1044. Tanimine N, Markmann JF, Wood-Trageser MA, Demetris AJ, Mason K, Silva JAF, Levitsky J, Feng S, Humar A, Emond JC, Shaked A, Klintmalm G, Sanchez-Fueyo A, Lesniak D, Breeden CP, Nepom GT, Bridges ND, Goldstein J, Larsen CP, DesMarais M, Gaile G, Chandran S. PMID: 39505152.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    8. Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation. Am J Transplant. 2025 Jan; 25(1):19-26. Chandran S, Vincenti F. PMID: 39384021.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial. Am J Transplant. 2024 Jul; 24(7):1193-1204. Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S. PMID: 38467375.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    10. Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. Cell Rep. 2023 07 25; 42(7):112682. Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Lee FE. PMID: 37355988; PMCID: PMC10391632.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    11. Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation. 2023 03 01; 107(3):564-569. Sykes M, Chandran S, Kawai T, Levitsky J, Mapara M, Mathew J, Thomson A, Yamada K. PMID: 36808845.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses. bioRxiv. 2023 Jan 20. Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Eun-Hyung Lee F. PMID: 36711623; PMCID: PMC9882341.
      View in: PubMed   Mentions:
    13. Impact of interleukin-6 on T cells in kidney transplant recipients. Am J Transplant. 2022 12; 22 Suppl 4:18-27. Chandran S, Tang Q. PMID: 36453710.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    14. Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial. J Am Soc Nephrol. 2023 01 01; 34(1):145-159. Hricik DE, Armstrong B, Alhamad T, Brennan DC, Bromberg JS, Bunnapradist S, Chandran S, Fairchild RL, Foley DP, Formica R, Gibson IW, Kesler K, Kim SJ, Mannon RB, Menon MC, Newell KA, Nickerson P, Odim J, Poggio ED, Sung R, Shapiro R, Tinckam K, Vincenti F, Heeger PS. PMID: 36195441; PMCID: PMC10101585.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    15. T cell-mediated rejection in kidney transplant recipients: The end(point) is also the beginning. Am J Transplant. 2022 03; 22(3):683-684. Chandran S, Mannon RB. PMID: 35073440.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Approaches to Establishing Tolerance in Immune Mediated Diseases. Front Immunol. 2021; 12:744804. Huffaker MF, Sanda S, Chandran S, Chung SA, St Clair EW, Nepom GT, Smilek DE. PMID: 34616405; PMCID: PMC8488342.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    17. Interleukin-6 blockade with tocilizumab increases Tregs and reduces T effector cytokines in renal graft inflammation: A randomized controlled trial. Am J Transplant. 2021 07; 21(7):2543-2554. Chandran S, Leung J, Hu C, Laszik ZG, Tang Q, Vincenti FG. PMID: 33331082.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    18. Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation. Front Genet. 2020; 11:610682. Zarinsefat A, Hartoularos G, Rychkov D, Rashmi P, Chandran S, Vincenti F, Yee CJ, Sarwal MM. PMID: 33469465; PMCID: PMC7813999.
      View in: PubMed   Mentions: 5  
    19. Treatment of immunocompromised COVID-19 patients with convalescent plasma. Transpl Infect Dis. 2021 Apr; 23(2):e13477. Fung M, Nambiar A, Pandey S, Aldrich JM, Teraoka J, Freise C, Roberts J, Chandran S, Hays SR, Bainbridge E, DeVoe C, Roque Gardner A, Yokoe D, Henrich TJ, Babik JM, Chin-Hong P. PMID: 32989856; PMCID: PMC7537112.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    20. The impact of belatacept on the phenotypic heterogeneity of renal T cell-mediated alloimmune response: The critical role of maintenance treatment and inflammatory load. Clin Transplant. 2020 11; 34(11):e14084. Dobi D, Vincenti F, Chandran S, Greenland JR, Bowman C, Chen A, Junger H, Laszik ZG. PMID: 32939817; PMCID: PMC8059253.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    21. Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation. bioRxiv. 2020 Oct 06. Zarinsefat A, Hartoularos G, Chandran S, Yee CJ, Vincenti F, Sarwal MM. PMID: 32935096; PMCID: PMC7491509.
      View in: PubMed   Mentions:
    22. The Fourth International Workshop on Clinical Transplant Tolerance. Am J Transplant. 2021 01; 21(1):21-31. Issa F, Strober S, Leventhal JR, Kawai T, Kaufman DB, Levitsky J, Sykes M, Mas V, Wood KJ, Bridges N, Welniak LA, Chandran S, Madsen JC, Nickerson P, Demetris AJ, Lakkis FG, Thomson AW. PMID: 32529725.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    23. Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States. Am J Transplant. 2020 11; 20(11):3225-3233. Fung M, Chiu CY, DeVoe C, Doernberg SB, Schwartz BS, Langelier C, Henrich TJ, Yokoe D, Davis J, Hays SR, Chandran S, Kukreja J, Ng D, Prostko J, Taylor R, Reyes K, Bainbridge E, Bond A, Chin-Hong P, Babik JM. PMID: 32476258; PMCID: PMC7300859.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCellsPHPublic Health
    24. Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience. Clin Transplant. 2017 Sep; 31(9). Wojciechowski D, Chandran S, Yang JYC, Sarwal MM, Vincenti F. PMID: 28662293.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Correlation of BK Virus Neutralizing Serostatus With the Incidence of BK Viremia in Kidney Transplant Recipients. Transplantation. 2017 06; 101(6):1495-1505. Abend JR, Changala M, Sathe A, Casey F, Kistler A, Chandran S, Howard A, Wojciechowski D. PMID: 27854236.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    26. Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients. Clin Transplant. 2017 05; 31(5). Wojciechowski D, Chandran S, Vincenti F. PMID: 28190259.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    27. BK Virus Infection After Kidney Transplantation: The Data Are Mounting for a Personalized Approach. Transplantation. 2016 Apr; 100(4):703-4. Wojciechowski D, Chandran S. PMID: 26760573.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Erratum to: Pharmacologic Targeting of Regulatory T Cells for Solid Organ Transplantation: Current and Future Prospects. Drugs. 2015 Dec; 75(18):2171. Safa K, Chandran S, Wojciechowski D. PMID: 26553341.
      View in: PubMed   Mentions:    Fields:    
    29. Pharmacologic targeting of regulatory T cells for solid organ transplantation: current and future prospects. Drugs. 2015 Nov; 75(16):1843-52. Safa K, Chandran S, Wojciechowski D. PMID: 26493288.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    30. Adjuvant Ciprofloxacin for Persistent BK Polyomavirus Infection in Kidney Transplant Recipients. J Transplant. 2014; 2014:107459. Arroyo D, Chandran S, Vagefi PA, Wojciechowski D. PMID: 25349720; PMCID: PMC4034659.
      View in: PubMed   Mentions: 6  
    31. Clinical aspects: focusing on key unique organ-specific issues of renal transplantation. Cold Spring Harb Perspect Med. 2014 Feb 01; 4(2). Chandran S, Vincenti F. PMID: 24370927; PMCID: PMC3904099.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Recurrent HIV-associated immune complex glomerulonephritis with lupus-like features after kidney transplantation. Am J Kidney Dis. 2013 Aug; 62(2):335-8. Chandran S, Jen KY, Laszik ZG. PMID: 23481367; PMCID: PMC4121438.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year. Transplantation. 2012 Dec 15; 94(11):1117-23. Wojciechowski D, Chanda R, Chandran S, Lee B, Webber A, Macaraig M, Tomlanovich S, Vincenti F. PMID: 23060281.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. The Akt pathway in human breast cancer: a tissue-array-based analysis. Mod Pathol. 2006 Feb; 19(2):238-45. Bose S, Chandran S, Mirocha JM, Bose N. PMID: 16341149.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
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