Tikvah Katheryn Hayes

Title(s)Assistant Professor, Molecular and Medical Pharmacology
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nat Commun. 2024 Mar 28; 15(1):2742. Hayes TK, Aquilanti E, Persky NS, Yang X, Kim EE, Brenan L, Goodale AB, Alan D, Sharpe T, Shue RE, Westlake L, Golomb L, Silverman BR, Morris MD, Fisher TR, Beyene E, Li YY, Cherniack AD, Piccioni F, Hicks JK, Chi AS, Cahill DP, Dietrich J, Batchelor TT, Root DE, Johannessen CM, Meyerson M. PMID: 38548752; PMCID: PMC10978866.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Molecular portraits of lung cancer evolution. Nature. 2023 04; 616(7957):435-436. Hayes TK, Meyerson M. PMID: 37045956.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    3. Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. Cell Rep. 2021 06 29; 35(13):109291. Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ. PMID: 34192548; PMCID: PMC8340308.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    4. Diversity Is a Strength of Cancer Research in the U.S. Cancer Cell. 2020 09 14; 38(3):297-300. Merad M, Posey AD, Olivero O, Singh PK, Mouneimne G, Li L, Wallace LM, Hayes TK. PMID: 32931736; PMCID: PMC7489360.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Genome-wide DNA methylation analysis of KRAS mutant cell lines. Sci Rep. 2020 06 23; 10(1):10149. Tew BY, Durand JK, Bryant KL, Hayes TK, Peng S, Tran NL, Gooden GC, Buckley DN, Der CJ, Baldwin AS, Salhia B. PMID: 32576853; PMCID: PMC7311523.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    6. Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. Nat Med. 2020 06; 26(6):982. Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, Diehl JN, Goode GD, Chaika NV, Wang Y, Zhang GF, Witkiewicz AK, Knudsen ES, Petricoin EF, Singh PK, Macdonald JM, Tran NL, Lyssiotis CA, Ying H, Kimmelman AC, Cox AD, Der CJ. PMID: 32483362.
      View in: PubMed   Mentions: 4     Fields:    
    7. Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12121-12130. Li YC, Lytle NK, Gammon ST, Wang L, Hayes TK, Sutton MN, Bast RC, Der CJ, Piwnica-Worms D, McCormick F, Wahl GM. PMID: 32424096; PMCID: PMC7275768.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    8. Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. Nat Med. 2019 04; 25(4):628-640. Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, Diehl JN, Goode GD, Chaika NV, Wang Y, Zhang GF, Witkiewicz AK, Knudsen ES, Petricoin EF, Singh PK, Macdonald JM, Tran NL, Lyssiotis CA, Ying H, Kimmelman AC, Cox AD, Der CJ. PMID: 30833752; PMCID: PMC6484853.
      View in: PubMed   Mentions: 287     Fields:    Translation:HumansAnimalsCells
    9. A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma. Cancer Res. 2019 05 01; 79(9):2352-2366. Hayes TK, Luo F, Cohen O, Goodale AB, Lee Y, Pantel S, Bagul M, Piccioni F, Root DE, Garraway LA, Meyerson M, Johannessen CM. PMID: 30819666; PMCID: PMC7227487.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    10. Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression. Cancer Cell. 2016 Jan 11; 29(1):75-89. Hayes TK, Neel NF, Hu C, Gautam P, Chenard M, Long B, Aziz M, Kassner M, Bryant KL, Pierobon M, Marayati R, Kher S, George SD, Xu M, Wang-Gillam A, Samatar AA, Maitra A, Wennerberg K, Petricoin EF, Yin HH, Nelkin B, Cox AD, Yeh JJ, Der CJ. PMID: 26725216; PMCID: PMC4816652.
      View in: PubMed   Mentions: 123     Fields:    Translation:AnimalsCells
    11. DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. PLoS Genet. 2014 Apr; 10(4):e1004277. Putnam CD, Pallis K, Hayes TK, Kolodner RD. PMID: 24699249; PMCID: PMC3974649.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    12. Mutant and wild-type Ras: co-conspirators in cancer. Cancer Discov. 2013 Jan; 3(1):24-6. Hayes TK, Der CJ. PMID: 23319767; PMCID: PMC3808242.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    13. Bioinformatic identification of genes suppressing genome instability. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):E3251-9. Putnam CD, Allen-Soltero SR, Martinez SL, Chan JE, Hayes TK, Kolodner RD. PMID: 23129647; PMCID: PMC3511103.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    14. The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector. Mol Cell Biol. 2012 Apr; 32(8):1374-86. Neel NF, Rossman KL, Martin TD, Hayes TK, Yeh JJ, Der CJ. PMID: 22331470; PMCID: PMC3318593.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    15. Post-replication repair suppresses duplication-mediated genome instability. PLoS Genet. 2010 May 06; 6(5):e1000933. Putnam CD, Hayes TK, Kolodner RD. PMID: 20463880; PMCID: PMC2865514.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    16. Specific pathways prevent duplication-mediated genome rearrangements. Nature. 2009 Aug 20; 460(7258):984-9. Putnam CD, Hayes TK, Kolodner RD. PMID: 19641493; PMCID: PMC2785216.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
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