William Zeiger

Title(s)Assistant Professor-in-Residence, Neurology
SchoolMedicine
ORCID ORCID Icon0000-0003-0567-2239 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Illinois at Urbana Champaign, Urbana, ILBS05/2005Molecular and Cellular Biology
    University of Chicago, Chicago, ILMD06/2013Medicine
    University of Chicago, Chicago, ILPhD06/2011Molecular Pathology & Molecular Medicine
    University of Chicago, Chicago, IL06/2014Medical Internship
    Johns Hopkins Hospital, Baltimore, MD06/2015Neurology PGY2
    University of California - Los Angeles, Los Angeles, CA06/2018Neurology Residency
    University of California - Los Angeles, Los Angeles, CA06/2020Movement Disorders Fellowship
    Collapse Awards and Honors
    University of California - Los Angeles2024The Dan Lewis Foundation for Brain Regeneration Research Prize
    University of California - Los Angeles2018The Jean-Louis Riehl Award for Outstanding Research as a Neurology Resident
    University of California - Los Angeles2018The Augustus S. Rose Award for Excellence in Teaching
    University of California - Los Angeles2018American Academy of Neurology Young Investigator Scholarship
    University of California - Los Angeles2017Excellence in Teaching with Humanism Residents and Fellows Award

    Collapse Overview 
    Collapse Overview
    Dr. Zeiger is a physician scientist in the Department of Neurology at UCLA. Clinically, Dr. Zeiger works as a neurologist specializing in movement disorders, particularly Parkinson disease and atypical parkinsonian disorders. Dr. Zeiger also runs a neuroscience research lab focused on investigating cortical circuit dysfunction in neurological disorders.

    Collapse Research 
    Collapse Research Activities and Funding
    Reciprocal interactions between cortical circuit dysfunction and a-synuclein pathology
    NIH R01NS129517Feb 1, 2023 - Jan 31, 2028
    Role: Principal Investigator
    Mechanisms of Somatosensory Circuit Remapping After Cortical Injury in Mice
    NIH K08NS114165Jul 15, 2021 - Jun 30, 2026
    Role: Principal Investigator
    The Role of Stanniocalcin 2 in Calcium Homeostasis and Neuronal Pathology
    NIH F30NS065660Jan 1, 2010 - Dec 31, 2012
    Role: Principal Investigator

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rethinking Remapping: Circuit Mechanisms of Recovery after Stroke. J Neurosci. 2023 11 08; 43(45):7489-7500. Campos B, Choi H, DeMarco AT, Seydell-Greenwald A, Hussain SJ, Joy MT, Turkeltaub PE, Zeiger W. PMID: 37940595; PMCID: PMC10634578.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. High-Sensitivity Intrinsic Optical Signal Imaging Through Flexible, Low-Cost Adaptations of an Upright Microscope. eNeuro. 2023 07; 10(8). Vasquez B, Campos B, Cao A, Theint AT, Zeiger W. PMID: 37550064; PMCID: PMC10408783.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    3. Abandoning the Proteinopathy Paradigm in Parkinson Disease-Not So Fast. JAMA Neurol. 2023 08 01; 80(8):872. Bronstein JM, Zeiger WA, Peng C. PMID: 37306984.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Two-photon calcium imaging of neuronal activity. Nat Rev Methods Primers. 2022; 2(1). Grienberger C, Giovannucci A, Zeiger W, Portera-Cailliau C. PMID: 38124998; PMCID: PMC10732251.
      View in: PubMed   Mentions: 26  
    5. Barrel cortex plasticity after photothrombotic stroke involves potentiating responses of pre-existing circuits but not functional remapping to new circuits. Nat Commun. 2021 06 25; 12(1):3972. Zeiger WA, Marosi M, Saggi S, Noble N, Samad I, Portera-Cailliau C. PMID: 34172735; PMCID: PMC8233353.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    6. Patterns and Perceptions of Smartphone Use Among Academic Neurologists in the United States: Questionnaire Survey. JMIR Mhealth Uhealth. 2020 12 24; 8(12):e22792. Zeiger W, DeBoer S, Probasco J. PMID: 33361053; PMCID: PMC7790607.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. EZcalcium: Open-Source Toolbox for Analysis of Calcium Imaging Data. Front Neural Circuits. 2020; 14:25. Cantu DA, Wang B, Gongwer MW, He CX, Goel A, Suresh A, Kourdougli N, Arroyo ED, Zeiger W, Portera-Cailliau C. PMID: 32499682; PMCID: PMC7244005.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    8. Spectro-temporal encoded multiphoton microscopy and fluorescence lifetime imaging at kilohertz frame-rates. Nat Commun. 2020 04 28; 11(1):2062. Karpf S, Riche CT, Di Carlo D, Goel A, Zeiger WA, Suresh A, Portera-Cailliau C, Jalali B. PMID: 32346060; PMCID: PMC7188897.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    9. Probable Diagnosis of a Patient with Niemann-Pick Disease Type C: Managing Pitfalls of Exome Sequencing. JIMD Rep. 2018; 41:47-51. Zeiger WA, Jamal NI, Scheuner MT, Pittman P, Raymond KM, Morra M, Mishra SK. PMID: 29453517; PMCID: PMC6122056.
      View in: PubMed   Mentions:
    10. Tactile Defensiveness and Impaired Adaptation of Neuronal Activity in the Fmr1 Knock-Out Mouse Model of Autism. J Neurosci. 2017 07 05; 37(27):6475-6487. He CX, Cantu DA, Mantri SS, Zeiger WA, Goel A, Portera-Cailliau C. PMID: 28607173; PMCID: PMC5511879.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    11. Acute Infantile Encephalopathy as Presentation of Succinic Semialdehyde Dehydrogenase Deficiency. Pediatr Neurol. 2016 05; 58:113-5. Zeiger WA, Sun LR, Bosemani T, Pearl PL, Stafstrom CE. PMID: 27268762.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Ca2+ influx through store-operated Ca2+ channels reduces Alzheimer disease β-amyloid peptide secretion. J Biol Chem. 2013 Sep 13; 288(37):26955-66. Zeiger W, Vetrivel KS, Buggia-Prévot V, Nguyen PD, Wagner SL, Villereal ML, Thinakaran G. PMID: 23902769; PMCID: PMC3772244.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    13. Stanniocalcin 2 is a negative modulator of store-operated calcium entry. Mol Cell Biol. 2011 Sep; 31(18):3710-22. Zeiger W, Ito D, Swetlik C, Oh-hora M, Villereal ML, Thinakaran G. PMID: 21746875; PMCID: PMC3165734.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    14. The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5765-70. Toogun OA, Zeiger W, Freeman BC. PMID: 17389357; PMCID: PMC1851566.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells