Albert J Courey

Title(s)Recalled Professor, Chemistry and Biochemistry
SchoolCollege of Letters and Science
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    SUMO conjugation in cell biology and Development
    NIH R01GM063596Sep 15, 2001 - Nov 30, 2012
    Role: Principal Investigator
    NIH S10RR008995Apr 1, 1995 - Mar 31, 1996
    Role: Principal Investigator
    Repressor/co-repressor oligomerization and development
    NIH R01GM044522Aug 7, 1990 - Jul 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Participation in a High-Structure General Chemistry Course Increases Student Sense of Belonging and Persistence to Organic Chemistry. J Chem Educ. 2023 Aug 08; 100(8):2860-2872. Casey JR, Supriya K, Shaked S, Caram JR, Russell A, Courey AJ. PMID: 37577453; PMCID: PMC10413951.
      View in: PubMed   Mentions:    Fields:    
    2. SUMO Interacting Motifs: Structure and Function. Cells. 2021 10 21; 10(11). Yau TY, Sander W, Eidson C, Courey AJ. PMID: 34831049; PMCID: PMC8616421.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    3. SUMOylation in development and neurodegeneration. Development. 2020 03 18; 147(6). Yau TY, Molina O, Courey AJ. PMID: 32188601; PMCID: PMC7097199.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    4. Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activity. BMC Genomics. 2017 02 28; 18(1):215. Chambers M, Turki-Judeh W, Kim MW, Chen K, Gallaher SD, Courey AJ. PMID: 28245789; PMCID: PMC5331681.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    5. SUMO in Drosophila Development. Adv Exp Med Biol. 2017; 963:249-257. Cao J, Courey AJ. PMID: 28197917.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. The central region of the Drosophila co-repressor Groucho as a regulatory hub. J Biol Chem. 2016 Mar 25; 291(13):6784. Kwong PN, Chambers M, Vashisht AA, Turki-Judeh W, Yau TY, Wohlschlegel JA, Courey AJ. PMID: 27016553; PMCID: PMC4807265.
      View in: PubMed   Mentions:    Fields:    
    7. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. J Biol Chem. 2015 Dec 11; 290(50):30119-30. Kwong PN, Chambers M, Vashisht AA, Turki-Judeh W, Yau TY, Wohlschlegel JA, Courey AJ. PMID: 26483546; PMCID: PMC4705979.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. SUMO as a solubility tag and in vivo cleavage of SUMO fusion proteins with Ulp1. Methods Mol Biol. 2014; 1177:71-80. Kuo D, Nie M, Courey AJ. PMID: 24943315.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    9. SUMOylation in Drosophila Development. Biomolecules. 2012 Jul 25; 2(3):331-49. Smith M, Turki-Judeh W, Courey AJ. PMID: 24970141; PMCID: PMC4030835.
      View in: PubMed   Mentions: 9     Fields:    
    10. The unconserved groucho central region is essential for viability and modulates target gene specificity. PLoS One. 2012; 7(2):e30610. Turki-Judeh W, Courey AJ. PMID: 22319573; PMCID: PMC3272004.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    11. Groucho: a corepressor with instructive roles in development. Curr Top Dev Biol. 2012; 98:65-96. Turki-Judeh W, Courey AJ. PMID: 22305159.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    12. Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg. J Biol Chem. 2011 Apr 01; 286(13):11391-400. Smith M, Mallin DR, Simon JA, Courey AJ. PMID: 21278366; PMCID: PMC3064195.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    13. Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. Development. 2011 Mar; 138(5):915-24. Ajuria L, Nieva C, Winkler C, Kuo D, Samper N, Andreu MJ, Helman A, González-Crespo S, Paroush Z, Courey AJ, Jiménez G. PMID: 21270056; PMCID: PMC3035094.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    14. A SUMO-Groucho Q domain fusion protein: characterization and in vivo Ulp1-mediated cleavage. Protein Expr Purif. 2011 Mar; 76(1):65-71. Kuo D, Nie M, De Hoff P, Chambers M, Phillips M, Hirsch AM, Courey AJ. PMID: 20732424; PMCID: PMC3005967.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    15. Groucho-mediated repression may result from a histone deacetylase-dependent increase in nucleosome density. PLoS One. 2010 Apr 13; 5(4):e10166. Winkler CJ, Ponce A, Courey AJ. PMID: 20405012; PMCID: PMC2854148.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    16. Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. PLoS One. 2009 Jun 16; 4(6):e5905. Nie M, Xie Y, Loo JA, Courey AJ. PMID: 19529778; PMCID: PMC2692000.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    17. Non-cell-autonomous inhibition of photoreceptor development by Dip3. Dev Biol. 2008 Nov 01; 323(1):105-13. Duong HA, Nagaraj R, Wang CW, Ratnaparkhi G, Sun YH, Courey AJ. PMID: 18761008; PMCID: PMC2614221.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Dorsal interacting protein 3 potentiates activation by Drosophila Rel homology domain proteins. Dev Comp Immunol. 2008; 32(11):1290-300. Ratnaparkhi GS, Duong HA, Courey AJ. PMID: 18538389; PMCID: PMC2603422.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    19. Transformation of eye to antenna by misexpression of a single gene. Mech Dev. 2008 Jan-Feb; 125(1-2):130-41. Duong HA, Wang CW, Sun YH, Courey AJ. PMID: 18037276; PMCID: PMC2225351.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    20. Uncoupling dorsal-mediated activation from dorsal-mediated repression in the Drosophila embryo. Development. 2006 Nov; 133(22):4409-14. Ratnaparkhi GS, Jia S, Courey AJ. PMID: 17035291.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    21. Directed Orientation of Antibodies during Preparation of Antibody Affinity Resin. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485605.
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    22. DNA affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485607.
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    23. Protein ligand affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485604.
      View in: PubMed   Mentions:
    24. Lectin-agarose affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485603.
      View in: PubMed   Mentions:
    25. Preparation of DNA affinity resin. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485606.
      View in: PubMed   Mentions:
    26. Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J. 2006 Jan 11; 25(1):70-9. Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU. PMID: 16362034; PMCID: PMC1356365.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    27. SUMO enhances vestigial function during wing morphogenesis. Mech Dev. 2005 Oct; 122(10):1130-7. Takanaka Y, Courey AJ. PMID: 16026969.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    28. Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response. Genes Dev. 2005 Aug 01; 19(15):1767-72. Song H, Nie M, Qiao F, Bowie JU, Courey AJ. PMID: 16027171; PMCID: PMC1182338.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    29. EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output. Nat Genet. 2005 Jan; 37(1):101-5. Hasson P, Egoz N, Winkler C, Volohonsky G, Jia S, Dinur T, Volk T, Courey AJ, Paroush Z. PMID: 15592470.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    30. Drosophila Ulp1, a nuclear pore-associated SUMO protease, prevents accumulation of cytoplasmic SUMO conjugates. J Biol Chem. 2004 Oct 15; 279(42):43805-14. Smith M, Bhaskar V, Fernandez J, Courey AJ. PMID: 15294908.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    31. Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell. 2004 Jul 23; 118(2):163-73. Qiao F, Song H, Kim CA, Sawaya MR, Hunter JB, Gingery M, Rebay I, Courey AJ, Bowie JU. PMID: 15260987.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    32. Groucho oligomerization is required for repression in vivo. Mol Cell Biol. 2004 May; 24(10):4341-50. Song H, Hasson P, Paroush Z, Courey AJ. PMID: 15121853; PMCID: PMC400465.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    33. The Dorsal Rel homology domain plays an active role in transcriptional regulation. Mol Cell Biol. 2002 Jul; 22(14):5089-99. Jia S, Flores-Saaib RD, Courey AJ. PMID: 12077338; PMCID: PMC139791.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    34. Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response. Mol Cell Biol. 2002 Jan; 22(2):492-504. Bhaskar V, Smith M, Courey AJ. PMID: 11756545; PMCID: PMC139748.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    35. Activation and repression by the C-terminal domain of Dorsal. Development. 2001 May; 128(10):1869-79. Flores-Saaib RD, Jia S, Courey AJ. PMID: 11311166.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    36. Cooperativity in transcriptional control. Curr Biol. 2001 Apr 03; 11(7):R250-2. Courey AJ. PMID: 11413011.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    37. Analysis of Groucho-histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression. Nucleic Acids Res. 2000 Nov 01; 28(21):4189-96. Flores-Saaib RD, Courey AJ. PMID: 11058116; PMCID: PMC113153.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    38. Groucho/TLE family proteins and transcriptional repression. Gene. 2000 May 16; 249(1-2):1-16. Chen G, Courey AJ. PMID: 10831834.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansAnimalsCells
    39. A functional interaction between dorsal and components of the Smt3 conjugation machinery. J Biol Chem. 2000 Feb 11; 275(6):4033-40. Bhaskar V, Valentine SA, Courey AJ. PMID: 10660560.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    40. Regulation of dorso/ventral patterning in the Drosophila embryo by multiple dorsal-interacting proteins. Cell Biochem Biophys. 2000; 33(1):1-17. Flores-Saaib RD, Courey AJ. PMID: 11322509.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    41. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev. 1999 Sep 01; 13(17):2218-30. Chen G, Fernandez J, Mische S, Courey AJ. PMID: 10485845; PMCID: PMC316998.
      View in: PubMed   Mentions: 173     Fields:    Translation:AnimalsCells
    42. Baculovirus-transfer vector for eukaryotic expression and immunoaffinity purification of Gal4-fusion proteins. Biotechniques. 1999 May; 26(5):808-10, 812, 814. Chen G, Courey AJ. PMID: 10337466.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    43. Analysis of altered DNA structures: cruciform DNA. Methods Mol Biol. 1999; 94:29-40. Courey AJ. PMID: 12844859.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    44. A role for Groucho tetramerization in transcriptional repression. Mol Cell Biol. 1998 Dec; 18(12):7259-68. Chen G, Nguyen PH, Courey AJ. PMID: 9819412; PMCID: PMC109307.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    45. Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer. Mol Cell Biol. 1998 Nov; 18(11):6584-94. Valentine SA, Chen G, Shandala T, Fernandez J, Mische S, Saint R, Courey AJ. PMID: 9774673; PMCID: PMC109243.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    46. Conversion of dorsal from an activator to a repressor by the global corepressor Groucho. Genes Dev. 1997 Nov 15; 11(22):2952-7. Dubnicoff T, Valentine SA, Chen G, Shi T, Lengyel JA, Paroush Z, Courey AJ. PMID: 9367978; PMCID: PMC316698.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    47. Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development. 1997 Nov; 124(21):4297-308. Rudolph KM, Liaw GJ, Daniel A, Green P, Courey AJ, Hartenstein V, Lengyel JA. PMID: 9334278.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    48. A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy. Mol Cell Biol. 1997 Jun; 17(6):3345-55. Shirokawa JM, Courey AJ. PMID: 9154833; PMCID: PMC232187.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    49. The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes Dev. 1995 Dec 15; 9(24):3163-76. Liaw GJ, Rudolph KM, Huang JD, Dubnicoff T, Courey AJ, Lengyel JA. PMID: 8543159.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    50. Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic. Genes Dev. 1995 Dec 15; 9(24):3177-89. Huang JD, Dubnicoff T, Liaw GJ, Bai Y, Valentine SA, Shirokawa JM, Lengyel JA, Courey AJ. PMID: 8543160.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    51. The decapentaplegic core promoter region plays an integral role in the spatial control of transcription. Mol Cell Biol. 1995 Jul; 15(7):3960-8. Schwyter DH, Huang JD, Dubnicoff T, Courey AJ. PMID: 7791801; PMCID: PMC230635.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    52. The establishment and interpretation of transcription factor gradients in the Drosophila embryo. Biochim Biophys Acta. 1995 Mar 14; 1261(1):1-18. Courey AJ, Huang JD. PMID: 7893745.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    53. The bipartite D. melanogaster twist promoter is reorganized in D. virilis. Mech Dev. 1994 Apr; 46(1):41-53. Pan D, Valentine SA, Courey AJ. PMID: 8068548.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    54. The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression. Genes Dev. 1993 Apr; 7(4):694-704. Huang JD, Schwyter DH, Shirokawa JM, Courey AJ. PMID: 8458580.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    55. Characterization of downstream elements in a Raf-1 pathway. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):858-62. Liaw GJ, Steingrimsson E, Pignoni F, Courey AJ, Lengyel JA. PMID: 8430097; PMCID: PMC45769.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    56. The same dorsal binding site mediates both activation and repression in a context-dependent manner. EMBO J. 1992 May; 11(5):1837-42. Pan D, Courey AJ. PMID: 1582412; PMCID: PMC556641.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    57. Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region. Genes Dev. 1991 Oct; 5(10):1892-901. Pan DJ, Huang JD, Courey AJ. PMID: 1655573.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    58. DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5670-4. Mastrangelo IA, Courey AJ, Wall JS, Jackson SP, Hough PV. PMID: 2062845; PMCID: PMC51939.
      View in: PubMed   Mentions: 92     Fields:    Translation:Cells
    59. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell. 1989 Dec 01; 59(5):827-36. Courey AJ, Holtzman DA, Jackson SP, Tjian R. PMID: 2512012.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansCells
    60. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science. 1988 Dec 16; 242(4885):1566-70. Kadonaga JT, Courey AJ, Ladika J, Tjian R. PMID: 3059495.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    61. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell. 1988 Dec 02; 55(5):887-98. Courey AJ, Tjian R. PMID: 3142690.
      View in: PubMed   Mentions: 439     Fields:    Translation:AnimalsCells
    62. The use of psoralen-modified DNA to probe the mechanism of enhancer action. Cell. 1986 May 23; 45(4):567-74. Courey AJ, Plon SE, Wang JC. PMID: 3011273.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    63. Cruciform formation in a negatively supercoiled DNA may be kinetically forbidden under physiological conditions. Cell. 1983 Jul; 33(3):817-29. Courey AJ, Wang JC. PMID: 6871994.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells