Albert J Courey

Title(s)Professor, Chemistry and Biochemistry
SchoolCollege of Letters and Science
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    SUMO conjugation in cell biology and Development
    NIH R01GM063596Sep 15, 2001 - Nov 30, 2012
    Role: Principal Investigator
    PHOSPHORIMAGER SYSTEM
    NIH S10RR008995Apr 1, 1995 - Mar 31, 1996
    Role: Principal Investigator
    Repressor/co-repressor oligomerization and development
    NIH R01GM044522Aug 7, 1990 - Jul 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. SUMO Interacting Motifs: Structure and Function. Cells. 2021 10 21; 10(11). Yau TY, Sander W, Eidson C, Courey AJ. PMID: 34831049; PMCID: PMC8616421.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. SUMOylation in development and neurodegeneration. Development. 2020 03 18; 147(6). Yau TY, Molina O, Courey AJ. PMID: 32188601; PMCID: PMC7097199.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    3. Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activity. BMC Genomics. 2017 02 28; 18(1):215. Chambers M, Turki-Judeh W, Kim MW, Chen K, Gallaher SD, Courey AJ. PMID: 28245789; PMCID: PMC5331681.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    4. SUMO in Drosophila Development. Adv Exp Med Biol. 2017; 963:249-257. Cao J, Courey AJ. PMID: 28197917.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. The central region of the Drosophila co-repressor Groucho as a regulatory hub. J Biol Chem. 2016 Mar 25; 291(13):6784. Kwong PN, Chambers M, Vashisht AA, Turki-Judeh W, Yau TY, Wohlschlegel JA, Courey AJ. PMID: 27016553; PMCID: PMC4807265.
      View in: PubMed   Mentions:    Fields:    
    6. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. J Biol Chem. 2015 Dec 11; 290(50):30119-30. Kwong PN, Chambers M, Vashisht AA, Turki-Judeh W, Yau TY, Wohlschlegel JA, Courey AJ. PMID: 26483546; PMCID: PMC4705979.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. SUMO as a solubility tag and in vivo cleavage of SUMO fusion proteins with Ulp1. Methods Mol Biol. 2014; 1177:71-80. Kuo D, Nie M, Courey AJ. PMID: 24943315.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    8. SUMOylation in Drosophila Development. Biomolecules. 2012 Jul 25; 2(3):331-49. Smith M, Turki-Judeh W, Courey AJ. PMID: 24970141; PMCID: PMC4030835.
      View in: PubMed   Mentions: 10     Fields:    
    9. The unconserved groucho central region is essential for viability and modulates target gene specificity. PLoS One. 2012; 7(2):e30610. Turki-Judeh W, Courey AJ. PMID: 22319573; PMCID: PMC3272004.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    10. Groucho: a corepressor with instructive roles in development. Curr Top Dev Biol. 2012; 98:65-96. Turki-Judeh W, Courey AJ. PMID: 22305159.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    11. Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg. J Biol Chem. 2011 Apr 01; 286(13):11391-400. Smith M, Mallin DR, Simon JA, Courey AJ. PMID: 21278366; PMCID: PMC3064195.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    12. Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. Development. 2011 Mar; 138(5):915-24. Ajuria L, Nieva C, Winkler C, Kuo D, Samper N, Andreu MJ, Helman A, González-Crespo S, Paroush Z, Courey AJ, Jiménez G. PMID: 21270056; PMCID: PMC3035094.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    13. A SUMO-Groucho Q domain fusion protein: characterization and in vivo Ulp1-mediated cleavage. Protein Expr Purif. 2011 Mar; 76(1):65-71. Kuo D, Nie M, De Hoff P, Chambers M, Phillips M, Hirsch AM, Courey AJ. PMID: 20732424; PMCID: PMC3005967.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    14. Groucho-mediated repression may result from a histone deacetylase-dependent increase in nucleosome density. PLoS One. 2010 Apr 13; 5(4):e10166. Winkler CJ, Ponce A, Courey AJ. PMID: 20405012; PMCID: PMC2854148.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    15. Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. PLoS One. 2009 Jun 16; 4(6):e5905. Nie M, Xie Y, Loo JA, Courey AJ. PMID: 19529778; PMCID: PMC2692000.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    16. Non-cell-autonomous inhibition of photoreceptor development by Dip3. Dev Biol. 2008 Nov 01; 323(1):105-13. Duong HA, Nagaraj R, Wang CW, Ratnaparkhi G, Sun YH, Courey AJ. PMID: 18761008; PMCID: PMC2614221.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    17. Dorsal interacting protein 3 potentiates activation by Drosophila Rel homology domain proteins. Dev Comp Immunol. 2008; 32(11):1290-300. Ratnaparkhi GS, Duong HA, Courey AJ. PMID: 18538389; PMCID: PMC2603422.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    18. Transformation of eye to antenna by misexpression of a single gene. Mech Dev. 2008 Jan-Feb; 125(1-2):130-41. Duong HA, Wang CW, Sun YH, Courey AJ. PMID: 18037276; PMCID: PMC2225351.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    19. Uncoupling dorsal-mediated activation from dorsal-mediated repression in the Drosophila embryo. Development. 2006 Nov; 133(22):4409-14. Ratnaparkhi GS, Jia S, Courey AJ. PMID: 17035291.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    20. DNA affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485607.
      View in: PubMed   Mentions:
    21. Protein ligand affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485604.
      View in: PubMed   Mentions:
    22. Directed Orientation of Antibodies during Preparation of Antibody Affinity Resin. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485605.
      View in: PubMed   Mentions:
    23. Lectin-agarose affinity chromatography. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485603.
      View in: PubMed   Mentions:
    24. Preparation of DNA affinity resin. CSH Protoc. 2006 Jun 01; 2006(1). Brocklehurst K, Courey AJ, Gul S, Lin SH, Moritz RL. PMID: 22485606.
      View in: PubMed   Mentions:
    25. Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J. 2006 Jan 11; 25(1):70-9. Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU. PMID: 16362034; PMCID: PMC1356365.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    26. SUMO enhances vestigial function during wing morphogenesis. Mech Dev. 2005 Oct; 122(10):1130-7. Takanaka Y, Courey AJ. PMID: 16026969.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    27. Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response. Genes Dev. 2005 Aug 01; 19(15):1767-72. Song H, Nie M, Qiao F, Bowie JU, Courey AJ. PMID: 16027171; PMCID: PMC1182338.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    28. EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output. Nat Genet. 2005 Jan; 37(1):101-5. Hasson P, Egoz N, Winkler C, Volohonsky G, Jia S, Dinur T, Volk T, Courey AJ, Paroush Z. PMID: 15592470.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    29. Drosophila Ulp1, a nuclear pore-associated SUMO protease, prevents accumulation of cytoplasmic SUMO conjugates. J Biol Chem. 2004 Oct 15; 279(42):43805-14. Smith M, Bhaskar V, Fernandez J, Courey AJ. PMID: 15294908.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    30. Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell. 2004 Jul 23; 118(2):163-73. Qiao F, Song H, Kim CA, Sawaya MR, Hunter JB, Gingery M, Rebay I, Courey AJ, Bowie JU. PMID: 15260987.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    31. Groucho oligomerization is required for repression in vivo. Mol Cell Biol. 2004 May; 24(10):4341-50. Song H, Hasson P, Paroush Z, Courey AJ. PMID: 15121853; PMCID: PMC400465.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    32. The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Gene. 2002 Oct 16; 299(1-2):173-84. Bhaskar V, Courey AJ. PMID: 12459265.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    33. The Dorsal Rel homology domain plays an active role in transcriptional regulation. Mol Cell Biol. 2002 Jul; 22(14):5089-99. Jia S, Flores-Saaib RD, Courey AJ. PMID: 12077338; PMCID: PMC139791.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    34. Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response. Mol Cell Biol. 2002 Jan; 22(2):492-504. Bhaskar V, Smith M, Courey AJ. PMID: 11756545; PMCID: PMC139748.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    35. Transcriptional repression: the long and the short of it. Genes Dev. 2001 Nov 01; 15(21):2786-96. Courey AJ, Jia S. PMID: 11691830.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    36. Activation and repression by the C-terminal domain of Dorsal. Development. 2001 May; 128(10):1869-79. Flores-Saaib RD, Jia S, Courey AJ. PMID: 11311166.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    37. Cooperativity in transcriptional control. Curr Biol. 2001 Apr 03; 11(7):R250-2. Courey AJ. PMID: 11413011.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    38. Analysis of Groucho-histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression. Nucleic Acids Res. 2000 Nov 01; 28(21):4189-96. Flores-Saaib RD, Courey AJ. PMID: 11058116; PMCID: PMC113153.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    39. Groucho/TLE family proteins and transcriptional repression. Gene. 2000 May 16; 249(1-2):1-16. Chen G, Courey AJ. PMID: 10831834.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCells
    40. A functional interaction between dorsal and components of the Smt3 conjugation machinery. J Biol Chem. 2000 Feb 11; 275(6):4033-40. Bhaskar V, Valentine SA, Courey AJ. PMID: 10660560.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    41. Regulation of dorso/ventral patterning in the Drosophila embryo by multiple dorsal-interacting proteins. Cell Biochem Biophys. 2000; 33(1):1-17. Flores-Saaib RD, Courey AJ. PMID: 11322509.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    42. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev. 1999 Sep 01; 13(17):2218-30. Chen G, Fernandez J, Mische S, Courey AJ. PMID: 10485845; PMCID: PMC316998.
      View in: PubMed   Mentions: 181     Fields:    Translation:AnimalsCells
    43. Baculovirus-transfer vector for eukaryotic expression and immunoaffinity purification of Gal4-fusion proteins. Biotechniques. 1999 May; 26(5):808-10, 812, 814. Chen G, Courey AJ. PMID: 10337466.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    44. Analysis of altered DNA structures: cruciform DNA. Methods Mol Biol. 1999; 94:29-40. Courey AJ. PMID: 12844859.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    45. A role for Groucho tetramerization in transcriptional repression. Mol Cell Biol. 1998 Dec; 18(12):7259-68. Chen G, Nguyen PH, Courey AJ. PMID: 9819412; PMCID: PMC109307.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    46. Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer. Mol Cell Biol. 1998 Nov; 18(11):6584-94. Valentine SA, Chen G, Shandala T, Fernandez J, Mische S, Saint R, Courey AJ. PMID: 9774673; PMCID: PMC109243.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    47. Conversion of dorsal from an activator to a repressor by the global corepressor Groucho. Genes Dev. 1997 Nov 15; 11(22):2952-7. Dubnicoff T, Valentine SA, Chen G, Shi T, Lengyel JA, Paroush Z, Courey AJ. PMID: 9367978; PMCID: PMC316698.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    48. Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development. 1997 Nov; 124(21):4297-308. Rudolph KM, Liaw GJ, Daniel A, Green P, Courey AJ, Hartenstein V, Lengyel JA. PMID: 9334278.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    49. A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy. Mol Cell Biol. 1997 Jun; 17(6):3345-55. Shirokawa JM, Courey AJ. PMID: 9154833; PMCID: PMC232187.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    50. The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes Dev. 1995 Dec 15; 9(24):3163-76. Liaw GJ, Rudolph KM, Huang JD, Dubnicoff T, Courey AJ, Lengyel JA. PMID: 8543159.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    51. Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic. Genes Dev. 1995 Dec 15; 9(24):3177-89. Huang JD, Dubnicoff T, Liaw GJ, Bai Y, Valentine SA, Shirokawa JM, Lengyel JA, Courey AJ. PMID: 8543160.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    52. The decapentaplegic core promoter region plays an integral role in the spatial control of transcription. Mol Cell Biol. 1995 Jul; 15(7):3960-8. Schwyter DH, Huang JD, Dubnicoff T, Courey AJ. PMID: 7791801; PMCID: PMC230635.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    53. The establishment and interpretation of transcription factor gradients in the Drosophila embryo. Biochim Biophys Acta. 1995 Mar 14; 1261(1):1-18. Courey AJ, Huang JD. PMID: 7893745.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    54. The bipartite D. melanogaster twist promoter is reorganized in D. virilis. Mech Dev. 1994 Apr; 46(1):41-53. Pan D, Valentine SA, Courey AJ. PMID: 8068548.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    55. The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression. Genes Dev. 1993 Apr; 7(4):694-704. Huang JD, Schwyter DH, Shirokawa JM, Courey AJ. PMID: 8458580.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    56. Characterization of downstream elements in a Raf-1 pathway. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):858-62. Liaw GJ, Steingrimsson E, Pignoni F, Courey AJ, Lengyel JA. PMID: 8430097; PMCID: PMC45769.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    57. The same dorsal binding site mediates both activation and repression in a context-dependent manner. EMBO J. 1992 May; 11(5):1837-42. Pan D, Courey AJ. PMID: 1582412; PMCID: PMC556641.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    58. Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region. Genes Dev. 1991 Oct; 5(10):1892-901. Pan DJ, Huang JD, Courey AJ. PMID: 1655573.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    59. DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5670-4. Mastrangelo IA, Courey AJ, Wall JS, Jackson SP, Hough PV. PMID: 2062845; PMCID: PMC51939.
      View in: PubMed   Mentions: 93     Fields:    Translation:Cells
    60. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell. 1989 Dec 01; 59(5):827-36. Courey AJ, Holtzman DA, Jackson SP, Tjian R. PMID: 2512012.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansCells
    61. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science. 1988 Dec 16; 242(4885):1566-70. Kadonaga JT, Courey AJ, Ladika J, Tjian R. PMID: 3059495.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    62. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell. 1988 Dec 02; 55(5):887-98. Courey AJ, Tjian R. PMID: 3142690.
      View in: PubMed   Mentions: 448     Fields:    Translation:AnimalsCells
    63. The use of psoralen-modified DNA to probe the mechanism of enhancer action. Cell. 1986 May 23; 45(4):567-74. Courey AJ, Plon SE, Wang JC. PMID: 3011273.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    64. Cruciform formation in a negatively supercoiled DNA may be kinetically forbidden under physiological conditions. Cell. 1983 Jul; 33(3):817-29. Courey AJ, Wang JC. PMID: 6871994.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells