Alexander M Van Der Bliek

Title(s)Professor, Biological Chemistry
SchoolMedicine
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    Collapse Research 
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    Control of calcium flux and mitochondrial fission by the Charcot Marie Tooth disease protein Mfn2.
    NIH R01NS120690Jan 1, 2020 - Nov 30, 2025
    Role: Principal Investigator
    Contributions of mitochondrial fission proteins to mitophagy
    NIH U01GM109764Aug 15, 2014 - May 31, 2018
    Role: Principal Investigator
    Mitochondrial Functions of Dynamin-Related Proteins
    NIH R01GM051866Aug 1, 1995 - Mar 31, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Quantification of cristae architecture reveals time-dependent characteristics of individual mitochondria. Life Sci Alliance. 2020 07; 3(7). Segawa M, Wolf DM, Hultgren NW, Williams DS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS. PMID: 32499316.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    2. Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. EMBO J. 2019 11 15; 38(22):e101056. Wolf DM, Segawa M, Kondadi AK, Anand R, Bailey ST, Reichert AS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS. PMID: 31609012.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    3. To Fis or not to Fuse? This is the question! EMBO J. 2019 04 15; 38(8). Liesa M, Van der Bliek A, Shirihai OS. PMID: 30936092.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle. Mol Metab. 2019 03; 21:51-67. Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, Whitelegge JP, Seldin MM, Lusis AJ, Lee S, Drevon CA, Mahata SK, Turcotte LP, Hevener AL. PMID: 30591411.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    5. Estrogen receptor a protects pancreatic ß-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J Biol Chem. 2018 03 30; 293(13):4735-4751. Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. PMID: 29378845.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    6. Cell Biology of the Mitochondrion. Genetics. 2017 11; 207(3):843-871. van der Bliek AM, Sedensky MM, Morgan PG. PMID: 29097398.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    7. GENETICS. Demystifying the demise of paternal mitochondrial DNA. Science. 2016 Jul 22; 353(6297):351-2. van der Bliek AM. PMID: 27463660.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Mitochondria just wanna have FUN(DC1). EMBO J. 2016 07 01; 35(13):1365-7. van der Bliek AM. PMID: 27283747; PMCID: PMC4931184.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    9. Organelles and spatial organization of the cell: organelle homeostasis and turnover. Mol Biol Cell. 2016 Mar 15; 27(6):873-4. van der Bliek A, Wang X. PMID: 26976928.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. J Cell Sci. 2015 Jun 15; 128(12):2236-48. Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML. PMID: 25956888.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    11. Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling. Science. 2014 Jun 27; 344(6191):1510-5. Boissan M, Montagnac G, Shen Q, Griparic L, Guitton J, Romao M, Sauvonnet N, Lagache T, Lascu I, Raposo G, Desbourdes C, Schlattner U, Lacombe ML, Polo S, van der Bliek AM, Roux A, Chavrier P. PMID: 24970086; PMCID: PMC4601533.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    12. Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol. 2014 Mar 31; 204(7):1083-6. Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J. PMID: 24687277.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    13. A dynamin-related protein contributes to Trichomonas vaginalis hydrogenosomal fission. FASEB J. 2014 Mar; 28(3):1113-21. Wexler-Cohen Y, Stevens GC, Barnoy E, van der Bliek AM, Johnson PJ. PMID: 24297697.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    14. Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol Biol Cell. 2014 Jan; 25(1):145-59. Shen Q, Yamano K, Head BP, Kawajiri S, Cheung JT, Wang C, Cho JH, Hattori N, Youle RJ, van der Bliek AM. PMID: 24196833.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    15. Mechanisms of mitochondrial fission and fusion. Cold Spring Harb Perspect Biol. 2013 Jun 01; 5(6). van der Bliek AM, Shen Q, Kawajiri S. PMID: 23732471.
      View in: PubMed   Mentions: 222     Fields:    Translation:Cells
    16. Mitochondrial fission, fusion, and stress. Science. 2012 Aug 31; 337(6098):1062-5. Youle RJ, van der Bliek AM. PMID: 22936770.
      View in: PubMed   Mentions: 924     Fields:    Translation:HumansAnimalsCells
    17. Analysis of membrane-bound organelles. Methods Cell Biol. 2012; 107:239-63. Fares H, van der Bliek AM. PMID: 22226526.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans. Mol Biol Cell. 2011 Mar 15; 22(6):831-41. Head BP, Zulaika M, Ryazantsev S, van der Bliek AM. PMID: 21248201.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    19. Dynamin subunit interactions revealed. Dev Cell. 2010 May 18; 18(5):687-8. van der Bliek AM, Payne GS. PMID: 20493800.
      View in: PubMed   Mentions: 9     Fields:    
    20. Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells. J Cell Biol. 2009 Dec 28; 187(7):959-66. Head B, Griparic L, Amiri M, Gandre-Babbe S, van der Bliek AM. PMID: 20038677; PMCID: PMC2806274.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansCells
    21. Fussy mitochondria fuse in response to stress. EMBO J. 2009 Jun 03; 28(11):1533-4. van der Bliek AM. PMID: 19494844.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    22. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. Mol Biol Cell. 2008 Jun; 19(6):2402-12. Gandre-Babbe S, van der Bliek AM. PMID: 18353969.
      View in: PubMed   Mentions: 283     Fields:    Translation:HumansAnimalsCells
    23. The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals. PLoS Genet. 2008 Feb 29; 4(2):e1000022. Kanazawa T, Zappaterra MD, Hasegawa A, Wright AP, Newman-Smith ED, Buttle KF, McDonald K, Mannella CA, van der Bliek AM. PMID: 18454199; PMCID: PMC2265488.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    24. Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage. J Cell Biol. 2007 Aug 27; 178(5):757-64. Griparic L, Kanazawa T, van der Bliek AM. PMID: 17709430; PMCID: PMC2064541.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansCells
    25. Inverse correlation between expression of the Wolfs Hirschhorn candidate gene Letm1 and mitochondrial volume in C. elegans and in mammalian cells. Hum Mol Genet. 2007 Sep 01; 16(17):2061-71. Hasegawa A, van der Bliek AM. PMID: 17606466.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    26. Mitochondrial division in Caenorhabditis elegans. Methods Mol Biol. 2007; 372:485-501. Gandre S, van der Bliek AM. PMID: 18314747.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    27. Assay and properties of the mitochondrial dynamin related protein Opa1. Methods Enzymol. 2005; 404:620-31. Griparic L, van der Bliek AM. PMID: 16413305.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria. J Biol Chem. 2004 Apr 30; 279(18):18792-8. Griparic L, van der Wel NN, Orozco IJ, Peters PJ, van der Bliek AM. PMID: 14970223.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansCells
    29. Mitochondrial morphology is dynamic and varied. Mol Cell Biochem. 2004 Jan-Feb; 256-257(1-2):331-9. Rube DA, van der Bliek AM. PMID: 14977192.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    30. Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron. 2003 Nov 13; 40(4):749-62. Schuske KR, Richmond JE, Matthies DS, Davis WS, Runz S, Rube DA, van der Bliek AM, Jorgensen EM. PMID: 14622579.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    31. A mitochondrial rhomboid protease. Dev Cell. 2003 Jun; 4(6):769-70. van der Bliek AM, Koehler CM. PMID: 12791261.
      View in: PubMed   Mentions: 10     Fields:    
    32. Composition and dynamics of human mitochondrial nucleoids. Mol Biol Cell. 2003 Apr; 14(4):1583-96. Garrido N, Griparic L, Jokitalo E, Wartiovaara J, van der Bliek AM, Spelbrink JN. PMID: 12686611.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansAnimalsCells
    33. A mitochondrial division apparatus takes shape. J Cell Biol. 2000 Oct 16; 151(2):F1-4. van der Bliek AM. PMID: 11038192.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    34. Is dynamin a regular motor or a master regulator? Trends Cell Biol. 1999 Jul; 9(7):253-4. van der Bliek AM. PMID: 10370239.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    35. Functional diversity in the dynamin family. Trends Cell Biol. 1999 Mar; 9(3):96-102. van der Bliek AM. PMID: 10201074.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
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