Orian Shirihai

Title(s)Professor, Medicine
SchoolMedicine
vCardDownload vCard
    Other Positions
    Title(s)Professor, Molecular and Medical Pharmacology


    Collapse Research 
    Collapse Research Activities and Funding
    MITOCHONDRIAL RESPIROMETRY IN FROZEN BIOLOGICAL SAMPLES
    NIH R41ES031043May 20, 2020 - Apr 30, 2021
    Role: Co-Principal Investigator
    A novel approach for reversal of autophagic defects using lysosome-targeted nanoparticles
    NIH R21AG060456Apr 15, 2019 - Feb 28, 2021
    Role: Principal Investigator
    R21: Acidic Nanoparticles for Restoration of Autophagy in Age-associated NAFLD
    NIH R21AG063373Apr 1, 2019 - Jan 31, 2021
    Role: Co-Principal Investigator
    OPTIMIZATION OF NANOPARTICLE TUMOR-LOCALIZATION AND DRUG-LOADING FOR TREATING MESOTHELIOMA
    NIH R01CA232056Feb 1, 2019 - Jan 31, 2024
    Role: Co-Principal Investigator
    Mitochondrial regulation of energy efficiency
    NIH R01DK099618Apr 1, 2014 - Mar 31, 2020
    Role: Principal Investigator
    Mitochondrial dynamics in beta cell function and dysfunction
    NIH R01DK074778Apr 1, 2006 - Jul 31, 2017
    Role: Principal Investigator
    Metabolic Profiling of Pancreatic Beta Cells
    NIH R21DK070303Sep 30, 2004 - Aug 31, 2007
    Role: Principal Investigator
    Erythroid transporter function in hemoglobin synthesis
    NIH R01HL071629Dec 3, 2002 - Nov 30, 2008
    Role: Principal Investigator
    Metabolic Signal Transduction in Adipocytes
    NIH R01DK056690Dec 1, 1999 - Jan 31, 2017
    Role: Co-Principal Investigator
    Metabolic Regulation of Insulin Secretion
    NIH R56DK035914Jan 1, 1987 - May 31, 2010
    Role: Co-Principal Investigator
    Metabolic Regulation of Insulin Secretion
    NIH R01DK035914Jul 1, 1985 - Dec 30, 2014
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice. Brain Sci. 2022 Jul 09; 12(7). Desai M, Stiles L, Torsoni AS, Torsoni MA, Shirihai OS, Ross MG. PMID: 35884707; PMCID: PMC9316209.
      View in: PubMed   Mentions:
    2. Mitoquinone mesylate targets SARS-CoV-2 and associated lung inflammation through host pathways. bioRxiv. 2022 Mar 09. Petcherski A, Sharma M, Daskou M, Satta S, Vasilopoulos H, Hugo C, Ritou E, Dillon BJ, Fung E, Garcia G, Scafoglio C, Purkayastha A, Gomperts BN, Fishbein GA, Arumugaswami V, Liesa M, Shirihai OS, Kelesidis T. PMID: 35233569; PMCID: PMC8887067.
      View in: PubMed   Mentions:
    3. The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells. Virulence. 2021 12; 12(1):2214-2227. Kelesidis T, Madhav S, Petcherski A, Cristelle H, O'Connor E, Hultgren NW, Ritou E, Williams DS, Shirihai OS, Reddy ST. PMID: 34494942; PMCID: PMC8437485.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance. Mol Metab. 2022 01; 55:101403. Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M. PMID: 34823065; PMCID: PMC8689243.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer. Commun Biol. 2021 11 16; 4(1):1289. Shen N, Korm S, Karantanos T, Li D, Zhang X, Ritou E, Xu H, Lam A, English J, Zong WX, Liu CT, Shirihai O, Feng H. PMID: 34785772; PMCID: PMC8595664.
      View in: PubMed   Mentions: 4  Translation:HumansCells
    6. ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity. Rev Endocr Metab Disord. 2022 02; 23(1):121-131. Brownstein AJ, Veliova M, Acin-Perez R, Liesa M, Shirihai OS. PMID: 34741717; PMCID: PMC8873062.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Mitochondrial Heterogeneity in Metabolic Diseases. Biology (Basel). 2021 Sep 17; 10(9). Ngo J, Osto C, Villalobos F, Shirihai OS. PMID: 34571805; PMCID: PMC8470264.
      View in: PubMed   Mentions: 1  
    8. Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives. Life (Basel). 2021 Sep 10; 11(9). Acin-Perez R, Benincá C, Shabane B, Shirihai OS, Stiles L. PMID: 34575097; PMCID: PMC8467772.
      View in: PubMed   Mentions: 2  
    9. Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease. Cell Rep. 2021 08 31; 36(9):109636. Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. PMID: 34469722; PMCID: PMC8432578.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    10. Recruitment and remodeling of peridroplet mitochondria in human adipose tissue. Redox Biol. 2021 10; 46:102087. Acín-Perez R, Petcherski A, Veliova M, Benador IY, Assali EA, Colleluori G, Cinti S, Brownstein AJ, Baghdasarian S, Livhits MJ, Yeh MW, Krishnan KC, Vergnes L, Winn NC, Padilla J, Liesa M, Sacks HS, Shirihai OS. PMID: 34411987; PMCID: PMC8377484.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. IRGM1 links mitochondrial quality control to autoimmunity. Nat Immunol. 2021 03; 22(3):312-321. Rai P, Janardhan KS, Meacham J, Madenspacher JH, Lin WC, Karmaus PWF, Martinez J, Li QZ, Yan M, Zeng J, Grinstaff MW, Shirihai OS, Taylor GA, Fessler MB. PMID: 33510463; PMCID: PMC7906953.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    12. High-Throughput Image Analysis of Lipid-Droplet-Bound Mitochondria. Methods Mol Biol. 2021; 2276:285-303. Miller N, Wolf D, Alsabeeh N, Mahdaviani K, Segawa M, Liesa M, Shirihai OS. PMID: 34060050.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue. STAR Protoc. 2021 03 19; 2(1):100243. Ngo J, Benador IY, Brownstein AJ, Vergnes L, Veliova M, Shum M, Acín-Pérez R, Reue K, Shirihai OS, Liesa M. PMID: 33458705; PMCID: PMC7797917.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling. EMBO Rep. 2020 12 03; 21(12):e49634. Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. PMID: 33275313; PMCID: PMC7726774.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    15. Measuring Mitochondrial Respiration in Previously Frozen Biological Samples. Curr Protoc Cell Biol. 2020 12; 89(1):e116. Osto C, Benador IY, Ngo J, Liesa M, Stiles L, Acin-Perez R, Shirihai OS. PMID: 33320426.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    16. Modulating lysosomal pH: a molecular and nanoscale materials design perspective. J Life Sci (Westlake Village). 2020 Dec; 2(4):25-37. Zeng J, Shirihai OS, Grinstaff MW. PMID: 33403369; PMCID: PMC7781074.
      View in: PubMed   Mentions: 4  
    17. Mitochondrial oxidative function in NAFLD: Friend or foe? Mol Metab. 2021 08; 50:101134. Shum M, Ngo J, Shirihai OS, Liesa M. PMID: 33276146; PMCID: PMC8324685.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics. Front Cell Dev Biol. 2020; 8:592035. Gonzalez-Ibanez AM, Ruiz LM, Jensen E, Echeverria CA, Romero V, Stiles L, Shirihai OS, Elorza AA. PMID: 33330472; PMCID: PMC7719720.
      View in: PubMed   Mentions: 6  
    19. Forces, fluxes, and fuels: tracking mitochondrial metabolism by integrating measurements of membrane potential, respiration, and metabolites. Am J Physiol Cell Physiol. 2021 01 01; 320(1):C80-C91. Jones AE, Sheng L, Acevedo A, Veliova M, Shirihai OS, Stiles L, Divakaruni AS. PMID: 33147057; PMCID: PMC7846976.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    20. Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity. Nat Metab. 2020 09; 2(9):974-988. Acín-Pérez R, Iborra S, Martí-Mateos Y, Cook ECL, Conde-Garrosa R, Petcherski A, Muñoz MDM, Martínez de Mena R, Krishnan KC, Jiménez C, Bolaños JP, Laakso M, Lusis AJ, Shirihai OS, Sancho D, Enríquez JA. PMID: 32943786; PMCID: PMC8225238.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    21. Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet-Induced Insulin Resistance in Mice. Mol Nutr Food Res. 2020 10; 64(19):e2000091. Yang J, Guo Y, Henning SM, Chan B, Long J, Zhong J, Acin-Perez R, Petcherski A, Shirihai O, Heber D, Li Z. PMID: 32783299; PMCID: PMC9185853.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    22. A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake. Redox Biol. 2020 10; 37:101676. Cerqueira FM, von Stockum S, Giacomello M, Goliand I, Kakimoto P, Marchesan E, De Stefani D, Kowaltowski AJ, Ziviani E, Shirihai OS. PMID: 32956978; PMCID: PMC7509235.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling. Sci Transl Med. 2020 08 05; 12(555). Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. PMID: 32759275; PMCID: PMC8212422.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    24. NCLX prevents cell death during adrenergic activation of the brown adipose tissue. Nat Commun. 2020 07 03; 11(1):3347. Assali EA, Jones AE, Veliova M, Acín-Pérez R, Taha M, Miller N, Shum M, Oliveira MF, Las G, Liesa M, Sekler I, Shirihai OS. PMID: 32620768; PMCID: PMC7334226.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Reply to: In vivo quantification of mitochondrial membrane potential. Nature. 2020 07; 583(7815):E19-E20. Momcilovic M, Shirihai O, Murphy MP, Koehler CM, Sadeghi S, Shackelford DB. PMID: 32641810.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    26. Quantification of cristae architecture reveals time-dependent characteristics of individual mitochondria. Life Sci Alliance. 2020 07; 3(7). Segawa M, Wolf DM, Hultgren NW, Williams DS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS. PMID: 32499316; PMCID: PMC7283135.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    27. The biology of lipid droplet-bound mitochondria. Semin Cell Dev Biol. 2020 12; 108:55-64. Veliova M, Petcherski A, Liesa M, Shirihai OS. PMID: 32446655; PMCID: PMC8019155.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. A novel approach to measure mitochondrial respiration in frozen biological samples. EMBO J. 2020 07 01; 39(13):e104073. Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. PMID: 32432379; PMCID: PMC7327496.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    29. COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10. J Biol Chem. 2020 05 01; 295(18):6023-6042. Bradley MC, Yang K, Fernández-Del-Río L, Ngo J, Ayer A, Tsui HS, Novales NA, Stocker R, Shirihai OS, Barros MH, Clarke CF. PMID: 32205446; PMCID: PMC7196636.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    30. Method for live-cell super-resolution imaging of mitochondrial cristae and quantification of submitochondrial membrane potentials. Methods Cell Biol. 2020; 155:545-555. Wolf DM, Segawa M, Shirihai OS, Liesa M. PMID: 32183976; PMCID: PMC7216778.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    31. Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner. EMBO Rep. 2020 03 04; 21(3):e49776. Kondadi AK, Anand R, Hänsch S, Urbach J, Zobel T, Wolf DM, Segawa M, Liesa M, Shirihai OS, Weidtkamp-Peters S, Reichert AS. PMID: 32067344; PMCID: PMC7054676.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    32. MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy. Biochem J. 2020 01 31; 477(2):461-475. Cerqueira FM, Kozer N, Petcherski A, Baranovski BM, Wolf D, Assali EA, Roth Y, Gazit R, Barr H, Lewis EC, Las G, Shirihai OS. PMID: 32003437.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. Emerging roles of β-cell mitochondria in type-2-diabetes. Mol Aspects Med. 2020 02; 71:100843. Las G, Oliveira MF, Shirihai OS. PMID: 31918997.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    34. Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2020 01; 577(7791):E7. Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31896820.
      View in: PubMed   Mentions:    Fields:    
    35. Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels. Diabetes. 2020 02; 69(2):131-145. Taddeo EP, Alsabeeh N, Baghdasarian S, Wikstrom JD, Ritou E, Sereda S, Erion K, Li J, Stiles L, Abdulla M, Swanson Z, Wilhelm JJ, Bellin MD, Kibbey RG, Liesa M, Shirihai OS. PMID: 31740442; PMCID: PMC6971491.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    36. Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. 2019 Nov; 575(7783):E5. Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, Dyson NJ, Haas W, Meissner A, Bardeesy N. PMID: 31695192.
      View in: PubMed   Mentions:    Fields:    
    37. In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2019 11; 575(7782):380-384. Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31666695; PMCID: PMC7328016.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    38. Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. EMBO J. 2019 11 15; 38(22):e101056. Wolf DM, Segawa M, Kondadi AK, Anand R, Bailey ST, Reichert AS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS. PMID: 31609012; PMCID: PMC6856616.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    39. Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis. FASEB J. 2019 12; 33(12):13176-13188. Kowaltowski AJ, Menezes-Filho SL, Assali EA, Gonçalves IG, Cabral-Costa JV, Abreu P, Miller N, Nolasco P, Laurindo FRM, Bruni-Cardoso A, Shirihai OS. PMID: 31480917; PMCID: PMC9272750.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    40. Publisher Correction: IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function. Nat Commun. 2019 Jul 31; 10(1):3507. Montemurro C, Nomoto H, Pei L, Parekh VS, Vongbunyong KE, Vadrevu S, Gurlo T, Butler AE, Subramaniam R, Ritou E, Shirihai OS, Satin LS, Butler PC, Tudzarova S. PMID: 31366929; PMCID: PMC6668385.
      View in: PubMed   Mentions: 1     Fields:    
    41. Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos. Cell Rep. 2019 07 16; 28(3):759-772.e10. Jesinkey SR, Madiraju AK, Alves TC, Yarborough OH, Cardone RL, Zhao X, Parsaei Y, Nasiri AR, Butrico G, Liu X, Molina AJ, Rountree AM, Neal AS, Wolf DM, Sterpka J, Philbrick WM, Sweet IR, Shirihai OH, Kibbey RG. PMID: 31315053; PMCID: PMC6713209.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    42. IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function. Nat Commun. 2019 06 18; 10(1):2679. Montemurro C, Nomoto H, Pei L, Parekh VS, Vongbunyong KE, Vadrevu S, Gurlo T, Butler AE, Subramaniam R, Ritou E, Shirihai OS, Satin LS, Butler PC, Tudzarova S. PMID: 31213603; PMCID: PMC6581914.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    43. To Fis or not to Fuse? This is the question! EMBO J. 2019 04 15; 38(8). Liesa M, Van der Bliek A, Shirihai OS. PMID: 30936092; PMCID: PMC6463207.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    44. Mitochondria Bound to Lipid Droplets: Where Mitochondrial Dynamics Regulate Lipid Storage and Utilization. Cell Metab. 2019 04 02; 29(4):827-835. Benador IY, Veliova M, Liesa M, Shirihai OS. PMID: 30905670; PMCID: PMC6476311.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    45. A Thermogenic-Like Brown Adipose Tissue Phenotype Is Dispensable for Enhanced Glucose Tolerance in Female Mice. Diabetes. 2019 09; 68(9):1717-1729. Winn NC, Acin-Perez R, Woodford ML, Hansen SA, Haney MM, Ayedun LA, Rector RS, Vieira-Potter VJ, Shirihai OS, Sacks HS, Kanaley JA, Padilla J. PMID: 30862679; PMCID: PMC6702635.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    46. The OXPHOS supercomplex assembly factor HIG2A responds to changes in energetic metabolism and cell cycle. J Cell Physiol. 2019 08; 234(10):17405-17419. Salazar C, Elorza AA, Cofre G, Ruiz-Hincapie P, Shirihai O, Ruiz LM. PMID: 30779122.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    47. Degradable Nanoparticles Restore Lysosomal pH and Autophagic Flux in Lipotoxic Pancreatic Beta Cells. Adv Healthc Mater. 2019 06; 8(12):e1801511. Zeng J, Shirihai OS, Grinstaff MW. PMID: 30698920.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    48. Nanoparticle-mediated lysosomal reacidification restores mitochondrial turnover and function in β cells under lipotoxicity. FASEB J. 2019 03; 33(3):4154-4165. Assali EA, Shlomo D, Zeng J, Taddeo EP, Trudeau KM, Erion KA, Colby AH, Grinstaff MW, Liesa M, Las G, Shirihai OS. PMID: 30550357; PMCID: PMC8793810.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    49. The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle. Mol Metab. 2019 03; 21:51-67. Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, Whitelegge JP, Seldin MM, Lusis AJ, Lee S, Drevon CA, Mahata SK, Turcotte LP, Hevener AL. PMID: 30591411; PMCID: PMC6407367.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    50. Individual islet respirometry reveals functional diversity within the islet population of mice and human donors. Mol Metab. 2018 10; 16:150-159. Taddeo EP, Stiles L, Sereda S, Ritou E, Wolf DM, Abdullah M, Swanson Z, Wilhelm J, Bellin M, McDonald P, Caradonna K, Neilson A, Liesa M, Shirihai OS. PMID: 30098928; PMCID: PMC6157638.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    51. Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling. iScience. 2018 Jul 27; 5:99-109. Waters LR, Ahsan FM, Wolf DM, Shirihai O, Teitell MA. PMID: 30240649; PMCID: PMC6123864.
      View in: PubMed   Mentions: 76  
    52. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer Metab. 2018; 6:7. Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. PMID: 29988332; PMCID: PMC6022704.
      View in: PubMed   Mentions: 6  
    53. Mitochondrial adaptation in obesity is a ClpPicated business. EMBO Rep. 2018 06; 19(6). Liesa M, Shirihai OS. PMID: 29789387; PMCID: PMC5989752.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    54. Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J. 2018 05 15; 37(10). Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. PMID: 29632021; PMCID: PMC5978453.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    55. Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion. Cell Metab. 2018 04 03; 27(4):869-885.e6. Benador IY, Veliova M, Mahdaviani K, Petcherski A, Wikstrom JD, Assali EA, Acín-Pérez R, Shum M, Oliveira MF, Cinti S, Sztalryd C, Barshop WD, Wohlschlegel JA, Corkey BE, Liesa M, Shirihai OS. PMID: 29617645; PMCID: PMC5969538.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    56. Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J Biol Chem. 2018 03 30; 293(13):4735-4751. Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. PMID: 29378845; PMCID: PMC5880140.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    57. Cell culture models of fatty acid overload: Problems and solutions. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Feb; 1863(2):143-151. Alsabeeh N, Chausse B, Kakimoto PA, Kowaltowski AJ, Shirihai O. PMID: 29155055; PMCID: PMC5969525.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    58. Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line. Cell Cycle. 2017; 16(21):2086-2099. Montemurro C, Vadrevu S, Gurlo T, Butler AE, Vongbunyong KE, Petcherski A, Shirihai OS, Satin LS, Braas D, Butler PC, Tudzarova S. PMID: 28820316; PMCID: PMC5731404.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    59. Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):E5167-E5176. Tkatch T, Greotti E, Baranauskas G, Pendin D, Roy S, Nita LI, Wettmarshausen J, Prigge M, Yizhar O, Shirihai OS, Fishman D, Hershfinkel M, Fleidervish IA, Perocchi F, Pozzan T, Sekler I. PMID: 28611221; PMCID: PMC5495261.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    60. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. EMBO Rep. 2017 07; 18(7):1123-1138. Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. PMID: 28539390; PMCID: PMC5887905.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    61. Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation. Cell Metab. 2017 May 02; 25(5):1160-1175.e11. Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M. PMID: 28467932; PMCID: PMC5501713.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    62. Modulation of mTOR signaling as a strategy for the treatment of Pompe disease. EMBO Mol Med. 2017 03; 9(3):353-370. Lim JA, Li L, Shirihai OS, Trudeau KM, Puertollano R, Raben N. PMID: 28130275; PMCID: PMC5331267.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    63. LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. 2016 11 17; 539(7629):390-395. Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, Dyson NJ, Haas W, Meissner A, Bardeesy N. PMID: 27799657; PMCID: PMC5988435.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    64. Proteinuria causes dysfunctional autophagy in the proximal tubule. Am J Physiol Renal Physiol. 2016 12 01; 311(6):F1271-F1279. Nolin AC, Mulhern RM, Panchenko MV, Pisarek-Horowitz A, Wang Z, Shirihai O, Borkan SC, Havasi A. PMID: 27582098; PMCID: PMC5210197.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    65. Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity. J Cell Biol. 2016 07 04; 214(1):25-34. Trudeau KM, Colby AH, Zeng J, Las G, Feng JH, Grinstaff MW, Shirihai OS. PMID: 27377248; PMCID: PMC4932370.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    66. Mitochondrial Networking in T Cell Memory. Cell. 2016 Jun 30; 166(1):9-10. Liesa M, Shirihai OS. PMID: 27368094.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    67. Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma. Biomaterials. 2016 09; 102:175-86. Liu R, Colby AH, Gilmore D, Schulz M, Zeng J, Padera RF, Shirihai O, Grinstaff MW, Colson YL. PMID: 27343465; PMCID: PMC4948582.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    68. Cellular Star Trek: A laser-based shuttle transfers mitochondria into cells. Mol Metab. 2016 Oct; 5(10):805-806. Las G, Shirihai O. PMID: 27688994; PMCID: PMC5034483.
      View in: PubMed   Mentions:    Fields:    
    69. BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell. PLoS One. 2016; 11(3):e0151329. Deeney JT, Belkina AC, Shirihai OS, Corkey BE, Denis GV. PMID: 27008626; PMCID: PMC4805167.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    70. Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity. FEBS J. 2016 Mar; 283(5):822-33. Cerqueira FM, Chausse B, Baranovski BM, Liesa M, Lewis EC, Shirihai OS, Kowaltowski AJ. PMID: 26732506.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    71. Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling. Atherosclerosis. 2016 04; 247:207-17. Fetterman JL, Holbrook M, Flint N, Feng B, Bretón-Romero R, Linder EA, Berk BD, Duess MA, Farb MG, Gokce N, Shirihai OS, Hamburg NM, Vita JA. PMID: 26926601; PMCID: PMC4913892.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    72. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1). Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. PMID: 26755553; PMCID: PMC4859372.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    73. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
      View in: PubMed   Mentions: 2567     Fields:    Translation:HumansAnimals
    74. Murine Mesenchymal Stem Cell Commitment to Differentiation Is Regulated by Mitochondrial Dynamics. Stem Cells. 2016 Mar; 34(3):743-55. Forni MF, Peloggia J, Trudeau K, Shirihai O, Kowaltowski AJ. PMID: 26638184; PMCID: PMC4803524.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    75. Assessment of Brown Adipocyte Thermogenic Function by High-throughput Respirometry. Bio Protoc. 2015 Nov 05; 5(21). Mahdaviani K, Benador I, Shirihai O. PMID: 29770346; PMCID: PMC5951411.
      View in: PubMed   Mentions:
    76. Autocrine effect of vascular endothelial growth factor-A is essential for mitochondrial function in brown adipocytes. Metabolism. 2016 Jan; 65(1):26-35. Mahdaviani K, Chess D, Wu Y, Shirihai O, Aprahamian TR. PMID: 26683794; PMCID: PMC4684900.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    77. Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle. Cell Metab. 2015 Nov 03; 22(5):936-47. Alves TC, Pongratz RL, Zhao X, Yarborough O, Sereda S, Shirihai O, Cline GW, Mason G, Kibbey RG. PMID: 26411341; PMCID: PMC4635072.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    78. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. J Clin Invest. 2015 Oct 01; 125(10):3847-60. Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. PMID: 26389676; PMCID: PMC4607115.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    79. Mutations in LRRK2 potentiate age-related impairment of autophagic flux. Mol Neurodegener. 2015 Jul 11; 10:26. Saha S, Ash PE, Gowda V, Liu L, Shirihai O, Wolozin B. PMID: 26159606; PMCID: PMC4702340.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    80. ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione. PLoS One. 2015; 10(6):e0129772. Qiu W, Liesa M, Carpenter EP, Shirihai OS. PMID: 26053025; PMCID: PMC4459825.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    81. How mitochondrial dynamism orchestrates mitophagy. Circ Res. 2015 May 22; 116(11):1835-49. Shirihai OS, Song M, Dorn GW. PMID: 25999423; PMCID: PMC4443843.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    82. Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. EMBO Mol Med. 2015 May; 7(5):688. Guan J, Mishra S, Qiu Y, Shi J, Trudeau K, Las G, Liesa M, Shirihai OS, Connors LH, Seldin DC, Falk RH, MacRae CA, Liao R. PMID: 25940533; PMCID: PMC4492824.
      View in: PubMed   Mentions: 5     Fields:    
    83. A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. Nat Commun. 2015 Apr 28; 6:7014. Qiao S, Dennis M, Song X, Vadysirisack DD, Salunke D, Nash Z, Yang Z, Liesa M, Yoshioka J, Matsuzawa S, Shirihai OS, Lee RT, Reed JC, Ellisen LW. PMID: 25916556; PMCID: PMC4421852.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    84. Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells. Stem Cell Reports. 2015 May 12; 4(5):873-85. Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, Lomas DA, Vallier L, Murphy GJ, Mostoslavsky G, Spira A, Shirihai OS, Ramirez MI, Gadue P, Kotton DN. PMID: 25843048; PMCID: PMC4437473.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    85. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. J Mol Cell Cardiol. 2015 Feb; 79:275-83. Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Colucci WS, Miller EJ. PMID: 25497302; PMCID: PMC4301992.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    86. Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. EMBO Mol Med. 2014 Nov; 6(11):1493-507. Guan J, Mishra S, Qiu Y, Shi J, Trudeau K, Las G, Liesa M, Shirihai OS, Connors LH, Seldin DC, Falk RH, MacRae CA, Liao R. PMID: 25319546; PMCID: PMC4237473.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    87. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015 Jan; 78:165-73. Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. PMID: 25109264; PMCID: PMC4268348.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    88. Miro1: new wheels for transferring mitochondria. EMBO J. 2014 May 02; 33(9):939-41. Las G, Shirihai OS. PMID: 24711517; PMCID: PMC4193928.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    89. Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus. Vasc Med. 2014 Feb; 19(1):67-74. Hartman ML, Shirihai OS, Holbrook M, Xu G, Kocherla M, Shah A, Fetterman JL, Kluge MA, Frame AA, Hamburg NM, Vita JA. PMID: 24558030; PMCID: PMC3932629.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    90. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J. 2014 Mar 03; 33(5):418-36. Wikstrom JD, Mahdaviani K, Liesa M, Sereda SB, Si Y, Las G, Twig G, Petrovic N, Zingaretti C, Graham A, Cinti S, Corkey BE, Cannon B, Nedergaard J, Shirihai OS. PMID: 24431221; PMCID: PMC3983686.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    91. Measurement of mitochondrial turnover and life cycle using MitoTimer. Methods Enzymol. 2014; 547:21-38. Trudeau KM, Gottlieb RA, Shirihai OS. PMID: 25416350.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    92. MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age. Autophagy. 2013 Nov 01; 9(11):1887-96. Ferree AW, Trudeau K, Zik E, Benador IY, Twig G, Gottlieb RA, Shirihai OS. PMID: 24149000; PMCID: PMC4028338.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    93. A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity. Mitochondrion. 2013 Nov; 13(6):662-7. Nickens KP, Wikstrom JD, Shirihai OS, Patierno SR, Ceryak S. PMID: 24075934; PMCID: PMC3837383.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    94. Optimal dynamics for quality control in spatially distributed mitochondrial networks. PLoS Comput Biol. 2013; 9(7):e1003108. Patel PK, Shirihai O, Huang KC. PMID: 23874166; PMCID: PMC3708874.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    95. Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells. Sci Transl Med. 2013 Jul 03; 5(192):192ra85. Kalghatgi S, Spina CS, Costello JC, Liesa M, Morones-Ramirez JR, Slomovic S, Molina A, Shirihai OS, Collins JJ. PMID: 23825301; PMCID: PMC3760005.
      View in: PubMed   Mentions: 160     Fields:    Translation:HumansAnimalsCells
    96. ATP-binding cassette B10 regulates early steps of heme synthesis. Circ Res. 2013 Jul 19; 113(3):279-87. Bayeva M, Khechaduri A, Wu R, Burke MA, Wasserstrom JA, Singh N, Liesa M, Shirihai OS, Langer NB, Paw BH, Ardehali H. PMID: 23720443; PMCID: PMC3817742.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    97. Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab. 2013 Apr 02; 17(4):491-506. Liesa M, Shirihai OS. PMID: 23562075; PMCID: PMC5967396.
      View in: PubMed   Mentions: 462     Fields:    Translation:HumansAnimalsCells
    98. Mitochondrial morphology transitions and functions: implications for retrograde signaling? Am J Physiol Regul Integr Comp Physiol. 2013 Mar 15; 304(6):R393-406. Picard M, Shirihai OS, Gentil BJ, Burelle Y. PMID: 23364527; PMCID: PMC3602821.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    99. Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice. PLoS One. 2012; 7(12):e51180. Guo W, Wong S, Li M, Liang W, Liesa M, Serra C, Jasuja R, Bartke A, Kirkland JL, Shirihai O, Bhasin S. PMID: 23240002; PMCID: PMC3519841.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    100. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. 2012 Oct; 60(4):949-56. Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. PMID: 22949535; PMCID: PMC3753106.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    101. Metabolic master regulators: sharing information among multiple systems. Trends Endocrinol Metab. 2012 Dec; 23(12):594-601. Corkey BE, Shirihai O. PMID: 22939743; PMCID: PMC3502692.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    102. Mitochondrial ABC transporters function: the role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species. Biochim Biophys Acta. 2012 Oct; 1823(10):1945-57. Liesa M, Qiu W, Shirihai OS. PMID: 22884976; PMCID: PMC3808996.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    103. Mitochondrial dynamics and morphology in beta-cells. Best Pract Res Clin Endocrinol Metab. 2012 Dec; 26(6):725-38. Stiles L, Shirihai OS. PMID: 23168275; PMCID: PMC5967392.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    104. A faster, high resolution, mtPA-GFP-based mitochondrial fusion assay acquiring kinetic data of multiple cells in parallel using confocal microscopy. J Vis Exp. 2012 Jul 20; (65):e3991. Lovy A, Molina AJ, Cerqueira FM, Trudeau K, Shirihai OS. PMID: 22847388; PMCID: PMC3476419.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    105. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Mol Cell Biol. 2012 Aug; 32(16):3333-46. Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P. PMID: 22711985; PMCID: PMC3434543.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    106. A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets. PLoS One. 2012; 7(5):e33023. Wikstrom JD, Sereda SB, Stiles L, Elorza A, Allister EM, Neilson A, Ferrick DA, Wheeler MB, Shirihai OS. PMID: 22606219; PMCID: PMC3351473.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    107. Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch Allergy Immunol. 2012; 159(1):23-32. Zhang B, Weng Z, Sismanopoulos N, Asadi S, Therianou A, Alysandratos KD, Angelidou A, Shirihai O, Theoharides TC. PMID: 22555146; PMCID: PMC4278585.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    108. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, et al. PMID: 22966490; PMCID: PMC3404883.
      View in: PubMed   Mentions: 1751     Fields:    Translation:HumansAnimals
    109. Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer. Cell. 2012 Feb 17; 148(4):651-63. Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, Shirihai OS, Chin L, DePinho RA. PMID: 22341440; PMCID: PMC3286017.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    110. Role of mitofusin 2 in the renal stress response. PLoS One. 2012; 7(1):e31074. Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RG. PMID: 22292091; PMCID: PMC3266928.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    111. Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. PLoS One. 2012; 7(1):e30200. Saadeh M, Ferrante TC, Kane A, Shirihai O, Corkey BE, Deeney JT. PMID: 22272304; PMCID: PMC3260220.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    112. Mitochondrial dynamics: the intersection of form and function. Adv Exp Med Biol. 2012; 748:13-40. Ferree A, Shirihai O. PMID: 22729853; PMCID: PMC5967395.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    113. Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition. Hum Mol Genet. 2012 Mar 01; 21(5):978-90. Gilkerson RW, De Vries RL, Lebot P, Wikstrom JD, Torgyekes E, Shirihai OS, Przedborski S, Schon EA. PMID: 22080835; PMCID: PMC3277306.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    114. Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion. Diabetes. 2011 Nov; 60(11):2710-9. Robson-Doucette CA, Sultan S, Allister EM, Wikstrom JD, Koshkin V, Bhattacharjee A, Prentice KJ, Sereda SB, Shirihai OS, Wheeler MB. PMID: 21984579; PMCID: PMC3198081.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    115. Fatty acids suppress autophagic turnover in β-cells. J Biol Chem. 2011 Dec 09; 286(49):42534-42544. Las G, Serada SB, Wikstrom JD, Twig G, Shirihai OS. PMID: 21859708; PMCID: PMC3234912.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    116. Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion. Circulation. 2011 Aug 16; 124(7):806-13. Liesa M, Luptak I, Qin F, Hyde BB, Sahin E, Siwik DA, Zhu Z, Pimentel DR, Xu XJ, Ruderman NB, Huffman KD, Doctrow SR, Richey L, Colucci WS, Shirihai OS. PMID: 21788586; PMCID: PMC4491919.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    117. Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus. Circulation. 2011 Jul 26; 124(4):444-53. Shenouda SM, Widlansky ME, Chen K, Xu G, Holbrook M, Tabit CE, Hamburg NM, Frame AA, Caiano TL, Kluge MA, Duess MA, Levit A, Kim B, Hartman ML, Joseph L, Shirihai OS, Vita JA. PMID: 21747057; PMCID: PMC3149100.
      View in: PubMed   Mentions: 228     Fields:    Translation:HumansCells
    118. The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells. Mol Biol Cell. 2011 Jul 01; 22(13):2235-45. Zhang Z, Wakabayashi N, Wakabayashi J, Tamura Y, Song WJ, Sereda S, Clerc P, Polster BM, Aja SM, Pletnikov MV, Kensler TW, Shirihai OS, Iijima M, Hussain MA, Sesaki H. PMID: 21551073; PMCID: PMC3128526.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    119. The interplay between mitochondrial dynamics and mitophagy. Antioxid Redox Signal. 2011 May 15; 14(10):1939-51. Twig G, Shirihai OS. PMID: 21128700; PMCID: PMC3078508.
      View in: PubMed   Mentions: 305     Fields:    Translation:HumansAnimalsCells
    120. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011 Apr 01; 25(7):717-29. Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. PMID: 21406549; PMCID: PMC3070934.
      View in: PubMed   Mentions: 671     Fields:    Translation:HumansAnimalsCells
    121. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011 Feb 17; 470(7334):359-65. Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA. PMID: 21307849; PMCID: PMC3741661.
      View in: PubMed   Mentions: 555     Fields:    Translation:AnimalsCells
    122. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature. 2010 Dec 02; 468(7324):659-63. Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, Tzatsos A, Ozsolak F, Milos P, Ferrari F, Park PJ, Shirihai OS, Scadden DT, Bardeesy N. PMID: 21124451; PMCID: PMC3037591.
      View in: PubMed   Mentions: 205     Fields:    Translation:AnimalsCells
    123. Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity. Am J Physiol Cell Physiol. 2010 Aug; 299(2):C477-87. Twig G, Liu X, Liesa M, Wikstrom JD, Molina AJ, Las G, Yaniv G, Hajnóczky G, Shirihai OS. PMID: 20445168; PMCID: PMC2928626.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    124. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell. 2010 Jan 22; 140(2):280-93. Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. PMID: 20141841; PMCID: PMC2821045.
      View in: PubMed   Mentions: 465     Fields:    Translation:AnimalsCells
    125. Organellar vs cellular control of mitochondrial dynamics. Semin Cell Dev Biol. 2010 Aug; 21(6):575-81. Hyde BB, Twig G, Shirihai OS. PMID: 20079451; PMCID: PMC3808978.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    126. Respiration in adipocytes is inhibited by reactive oxygen species. Obesity (Silver Spring). 2010 Aug; 18(8):1493-502. Wang T, Si Y, Shirihai OS, Si H, Schultz V, Corkey RF, Hu L, Deeney JT, Guo W, Corkey BE. PMID: 20035277; PMCID: PMC6154476.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    127. Insulin signaling regulates mitochondrial function in pancreatic beta-cells. PLoS One. 2009 Nov 24; 4(11):e7983. Liu S, Okada T, Assmann A, Soto J, Liew CW, Bugger H, Shirihai OS, Abel ED, Kulkarni RN. PMID: 19956695; PMCID: PMC2776992.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    128. Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content. J Immunol. 2009 Nov 15; 183(10):6313-9. Tagen M, Elorza A, Kempuraj D, Boucher W, Kepley CL, Shirihai OS, Theoharides TC. PMID: 19846869; PMCID: PMC2925218.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    129. Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics. EMBO J. 2009 Oct 21; 28(20):3074-89. Liu X, Weaver D, Shirihai O, Hajnóczky G. PMID: 19745815; PMCID: PMC2771091.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    130. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38):16263-8. Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH. PMID: 19805291; PMCID: PMC2752562.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    131. The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets. Obesity (Silver Spring). 2009 Oct; 17(10):1856-60. Getty-Kaushik L, Richard AM, Deeney JT, Krawczyk S, Shirihai O, Corkey BE. PMID: 19644453; PMCID: PMC3808997.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    132. Mitochondrial networking protects beta-cells from nutrient-induced apoptosis. Diabetes. 2009 Oct; 58(10):2303-15. Molina AJ, Wikstrom JD, Stiles L, Las G, Mohamed H, Elorza A, Walzer G, Twig G, Katz S, Corkey BE, Shirihai OS. PMID: 19581419; PMCID: PMC2750232.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    133. What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy? Int J Biochem Cell Biol. 2009 Oct; 41(10):1914-27. Wikstrom JD, Twig G, Shirihai OS. PMID: 19549572.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    134. Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function. Biophys J. 2009 May 06; 96(9):3509-18. Mouli PK, Twig G, Shirihai OS. PMID: 19413957; PMCID: PMC2711405.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    135. Monitoring mitochondrial dynamics with photoactivatable [corrected] green fluorescent protein. Methods Enzymol. 2009; 457:289-304. Molina AJ, Shirihai OS. PMID: 19426874; PMCID: PMC5967387.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    136. UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. J Biol Chem. 2008 Nov 07; 283(45):30461-70. Elorza A, Hyde B, Mikkola HK, Collins S, Shirihai OS. PMID: 18687678; PMCID: PMC2576537.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    137. Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta. 2008 Sep; 1777(9):1092-7. Twig G, Hyde B, Shirihai OS. PMID: 18519024; PMCID: PMC3809017.
      View in: PubMed   Mentions: 282     Fields:    Translation:HumansAnimalsCells
    138. Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 2008 Feb; 14(2):144-53. Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ. PMID: 18223655; PMCID: PMC3918232.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    139. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 2008 Jan 23; 27(2):433-46. Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS. PMID: 18200046; PMCID: PMC2234339.
      View in: PubMed   Mentions: 1303     Fields:    Translation:AnimalsCells
    140. beta-Cell mitochondria exhibit membrane potential heterogeneity that can be altered by stimulatory or toxic fuel levels. Diabetes. 2007 Oct; 56(10):2569-78. Wikstrom JD, Katzman SM, Mohamed H, Twig G, Graf SA, Heart E, Molina AJ, Corkey BE, de Vargas LM, Danial NN, Collins S, Shirihai OS. PMID: 17686943.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    141. Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. Biochem J. 2007 Apr 01; 403(1):197-205. Heart E, Yaney GC, Corkey RF, Schultz V, Luc E, Liu L, Deeney JT, Shirihai O, Tornheim K, Smith PJ, Corkey BE. PMID: 17181533; PMCID: PMC1828901.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    142. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood. 2007 Jul 01; 110(1):125-32. Sheftel AD, Zhang AS, Brown C, Shirihai OS, Ponka P. PMID: 17376890.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    143. PA-GFP: a window into the subcellular adventures of the individual mitochondrion. Novartis Found Symp. 2007; 287:21-36; discussion 36-46. Haigh SE, Twig G, Molina AA, Wikstrom JD, Deutsch M, Shirihai OS. PMID: 18074629.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    144. A novel miniature cell retainer for correlative high-content analysis of individual untethered non-adherent cells. Lab Chip. 2006 Aug; 6(8):995-1000. Deutsch M, Deutsch A, Shirihai O, Hurevich I, Afrimzon E, Shafran Y, Zurgil N. PMID: 16874368.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    145. Tagging and tracking individual networks within a complex mitochondrial web with photoactivatable GFP. Am J Physiol Cell Physiol. 2006 Jul; 291(1):C176-84. Twig G, Graf SA, Wikstrom JD, Mohamed H, Haigh SE, Elorza A, Deutsch M, Zurgil N, Reynolds N, Shirihai OS. PMID: 16481372.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    146. Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells. Am J Physiol Endocrinol Metab. 2006 Jan; 290(1):E143-E148. Heart E, Corkey RF, Wikstrom JD, Shirihai OS, Corkey BE. PMID: 16144817.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    147. Synergistic amplification of beta-amyloid- and interferon-gamma-induced microglial neurotoxic response by the senile plaque component chromogranin A. Am J Physiol Cell Physiol. 2005 Jan; 288(1):C169-75. Twig G, Graf SA, Messerli MA, Smith PJ, Yoo SH, Shirihai OS. PMID: 15342341.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    148. Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me). J Biol Chem. 2004 Oct 08; 279(41):42954-63. Graf SA, Haigh SE, Corson ED, Shirihai OS. PMID: 15215243.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    149. SUMO-1 protease-1 regulates gene transcription through PML. Mol Cell. 2002 Oct; 10(4):843-55. Best JL, Ganiatsas S, Agarwal S, Changou A, Salomoni P, Shirihai O, Meluh PB, Pandolfi PP, Zon LI. PMID: 12419228.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    Orian's Networks
    Concepts (621)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (64)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCLA Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version v3.1.0-871-g21b54b14 on PROFILES-PWEB01.

    Copyright © The Regents of the University of California