Brigitte N Gomperts

Title(s)Professor, Pediatrics
SchoolMedicine
ORCID ORCID Icon0000-0002-1809-723X Additional info
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    Other Positions
    Title(s)Professor, Medicine


    Collapse Biography 
    Collapse Education and Training
    University of the Witwatersrand, Johannesburg, South AfricaMD equivalent12/1993Medicine and Surgery
    Washington University St. Louis, St. Louis, MO06/2000Pediatrics Residency and Chief Residency
    Washington University St. Louis, St. Louis, MO06/2003Pediatric Hematology-Oncology Fellowship

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Validation of an in vitro model of progressive fibrosis that mimics Idiopathic Pulmonary Fibrosis
    NIH U01HL153000Feb 15, 2021 - Jan 31, 2025
    Role: Principal Investigator
    Targeting DNA Damage Repair Pathways to Reduce SARS-CoV-2 Replication in the Airways
    Department of Defense PR202868Feb 1, 2021 - Jan 31, 2025
    Role: Principle Investigator
    Description: The goal is to repurpose a drug for COVID-19 by testing toxicity and efficacy in in vitro and in vivo lung smoking models.
    Translational models for drug discovery for IPF
    Three Lakes Foundation CurePF-Translational Models for Pulmonary FibrosisJan 1, 2021 - Jan 1, 2024
    Description: The goal is o develop novel models of Idiopathic Pulmonary Fibrosis and develop them for drug screening
    Understanding the effects of e-cigarettes on airway epithelial repair and homeostasis
    UCOP-Tobacco-Related Disease Research Program T31IR1637Aug 1, 2020 - Jul 31, 2023
    Description: The goal is to develop an aerosolized toxicity screen to test e-cigarette components to inform FDA regulation of different e-cigarette products
    Burroughs Wellcome Fund 1020030Sep 1, 2019 - Aug 30, 2024
    Increasing our understanding of airway basal stem cells and their function
    Cystic Fibrosis Foundation Stem Cell ConsortiumMar 1, 2018 - Feb 28, 2024
    Description: The goal is to understand basal stem cells in healthy and CF airway with a long-term view towards cell therapies.
    Developing a targeted chemoprevention strategy for Non-Small Cell Lung Cancer
    NIH R01CA208303Aug 15, 2016 - Jul 31, 2021
    Role: Principal Investigator
    Development of a High-Throughput Screen for Pre-therapeutic Discovery in Idiopathic Pulmonary Fibrosis
    NIH R01GM114259Mar 1, 2015 - Feb 28, 2019
    Role: Principal Investigator
    Progenitor Cells in Airway Repair
    NIH R01HL094561Sep 1, 2009 - Jul 31, 2015
    Role: Principal Investigator
    Cytokine Regulation of the Pulmonary Epithelium
    NIH K08HL074229Dec 15, 2004 - Nov 30, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Light-field tomographic fluorescence lifetime imaging microscopy. Proc Natl Acad Sci U S A. 2024 Oct; 121(40):e2402556121. Ma Y, Park J, Huang L, Sen C, Burri S, Bruschini C, Yang X, Cui Q, Cameron RB, Fishbein GA, Gomperts BN, Ozcan A, Charbon E, Gao L. PMID: 39320920; PMCID: PMC11459138.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    2. Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis. bioRxiv. 2024 Jun 22. Chandran RR, Vijayaraj P, Garcia-Milian R, King J, Castillo K, Chen L, Kwon Y, William S, Rickabaugh TM, Langerman J, Choi W, Sen C, Lever JEP, Li Q, Pavelkova N, Plosa EJ, Rowe SM, Plath K, Clair G, Gomperts BN. PMID: 38948715; PMCID: PMC11212876.
      View in: PubMed   Mentions:
    3. Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease. Front Cell Dev Biol. 2024; 12:1335061. Chandran RR, Adams TS, Kabir I, Gallardo-Vara E, Kaminski N, Gomperts BN, Greif DM. PMID: 38572485; PMCID: PMC10987733.
      View in: PubMed   Mentions: 1  
    4. Orbital indeterminate cell histiocytosis. Orbit. 2024 Feb 19; 1-5. Oh AJ, Sears CM, Vadivelan AA, Gomperts BN, Federman N, Said J, Roelofs KA. PMID: 38374584.
      View in: PubMed   Mentions:    Fields:    
    5. Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report. Am J Respir Crit Care Med. 2024 02 15; 209(4):362-373. Montesi SB, Gomez CR, Beers M, Brown R, Chattopadhyay I, Flaherty KR, Garcia CK, Gomperts B, Hariri LP, Hogaboam CM, Jenkins RG, Kaminski N, Kim GHJ, Königshoff M, Kolb M, Kotton DN, Kropski JA, Lasky J, Magin CM, Maher TM, McCormick M, Moore BB, Nickerson-Nutter C, Oldham J, Podolanczuk AJ, Raghu G, Rosas I, Rowe SM, Schmidt WT, Schwartz D, Shore JE, Spino C, Craig JM, Martinez FJ. PMID: 38113442; PMCID: PMC10878386.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging. J Clin Invest. 2023 12 15; 133(24). Mason EC, Menon S, Schneider BR, Gaskill CF, Dawson MM, Moore CM, Armstrong LC, Cho O, Richmond BW, Kropski JA, West JD, Geraghty P, Gomperts BN, Ess KC, Gally F, Majka SM. PMID: 37874650; PMCID: PMC10721153.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles. MedComm (2020). 2023 Oct; 4(5):e400. Cui Q, Jeyachandran AV, Garcia G, Qin C, Zhou Y, Zhang M, Wang C, Sun G, Liu W, Zhou T, Feng L, Palmer C, Li Z, Aziz A, Gomperts BN, Feng P, Arumugaswami V, Shi Y. PMID: 37822714; PMCID: PMC10563865.
      View in: PubMed   Mentions: 3  
    8. Development of a small cell lung cancer organoid model to study cellular interactions and survival after chemotherapy. Front Pharmacol. 2023; 14:1211026. Sen C, Koloff CR, Kundu S, Wilkinson DC, Yang JM, Shia DW, Meneses LK, Rickabaugh TM, Gomperts BN. PMID: 37608896; PMCID: PMC10441219.
      View in: PubMed   Mentions: 6  
    9. Light-field tomographic fluorescence lifetime imaging microscopy. Res Sq. 2023 May 10. Ma Y, Huang L, Sen C, Burri S, Bruschini C, Yang X, Cameron RB, Fishbein GA, Gomperts BN, Ozcan A, Charbon E, Gao L. PMID: 37214842; PMCID: PMC10197779.
      View in: PubMed   Mentions:
    10. Small cell lung cancer co-culture organoids provide insights into cancer cell survival after chemotherapy. bioRxiv. 2023 Jan 12. Sen C, Koloff C, Kundu S, Wilkinson DC, Yang J, Shia DW, Meneses LK, Rickabaugh TM, Gomperts BN. PMID: 36711908; PMCID: PMC9881945.
      View in: PubMed   Mentions:
    11. Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene. 2023 02; 42(6):434-448. Shia DW, Choi W, Vijayaraj P, Vuong V, Sandlin JM, Lu MM, Aziz A, Marin C, Aros CJ, Sen C, Durra A, Lund AJ, Purkayastha A, Rickabaugh TM, Graeber TG, Gomperts BN. PMID: 36509998; PMCID: PMC9898033.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    12. Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response. PLoS Biol. 2022 11; 20(11):e3001851. Garcia G, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. PMID: 36346780; PMCID: PMC9642871.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models. bioRxiv. 2022 Jun 23. Petcherski A, Sharma M, Daskou M, Satta S, Vasilopoulos H, Hugo C, Ritou E, Dillon BJ, Fung E, Garcia G, Scafoglio C, Purkayastha A, Gomperts BN, Fishbein GA, Arumugaswami V, Liesa M, Shirihai OS, Kelesidis T. PMID: 35233569; PMCID: PMC8887067.
      View in: PubMed   Mentions: 1  
    14. Three-dimensional models of the lung: past, present and future: a mini review. Biochem Soc Trans. 2022 04 29; 50(2):1045-1056. Sen C, Freund D, Gomperts BN. PMID: 35411381.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response. bioRxiv. 2022 Apr 08. Garcia G, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V. PMID: 35441167; PMCID: PMC9016637.
      View in: PubMed   Mentions:
    16. Wnt signaling in lung development, regeneration, and disease progression. Commun Biol. 2021 05 20; 4(1):601. Aros CJ, Pantoja CJ, Gomperts BN. PMID: 34017045; PMCID: PMC8138018.
      View in: PubMed   Mentions: 47  Translation:HumansAnimalsCells
    17. Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition. Nat Med. 2021 05; 27(5):806-814. Carraro G, Langerman J, Sabri S, Lorenzana Z, Purkayastha A, Zhang G, Konda B, Aros CJ, Calvert BA, Szymaniak A, Wilson E, Mulligan M, Bhatt P, Lu J, Vijayaraj P, Yao C, Shia DW, Lund AJ, Israely E, Rickabaugh TM, Ernst J, Mense M, Randell SH, Vladar EK, Ryan AL, Plath K, Mahoney JE, Stripp BR, Gomperts BN. PMID: 33958799; PMCID: PMC9009537.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    18. SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. Cell Rep. 2021 05 04; 35(5):109055. Mulay A, Konda B, Garcia G, Yao C, Beil S, Villalba JM, Koziol C, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. PMID: 33905739; PMCID: PMC8043574.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansCells
    19. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183; PMCID: PMC7994801.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    20. Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication. Cell Rep. 2021 04 06; 35(1):108940. Garcia G, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. PMID: 33784499; PMCID: PMC7969873.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    21. Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response. Cell Stem Cell. 2020 12 03; 27(6):869-875.e4. Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 33259798; PMCID: PMC7670932.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    22. Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response. bioRxiv. 2020 Jul 29. Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 32766588; PMCID: PMC7402049.
      View in: PubMed   Mentions:
    23. Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging. Cell Stem Cell. 2020 09 03; 27(3):413-429.e4. Aros CJ, Vijayaraj P, Pantoja CJ, Bisht B, Meneses LK, Sandlin JM, Tse JA, Chen MW, Purkayastha A, Shia DW, Sucre JMS, Rickabaugh TM, Vladar EK, Paul MK, Gomperts BN. PMID: 32721381; PMCID: PMC7484054.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    24. High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis. Cell Rep. 2020 02 18; 30(7):2055-2064.e5. Aros CJ, Paul MK, Pantoja CJ, Bisht B, Meneses LK, Vijayaraj P, Sandlin JM, France B, Tse JA, Chen MW, Shia DW, Rickabaugh TM, Damoiseaux R, Gomperts BN. PMID: 32075752; PMCID: PMC7050206.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    25. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Rep. 2019 12 10; 29(11):3488-3505.e9. Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, Yan W, Clark AT, Rickabaugh TM, Wallace WD, Graeber TG, Damoiseaux R, Gomperts BN. PMID: 31825831; PMCID: PMC6927560.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    26. Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. Cancer Cell. 2019 07 08; 36(1):17-34.e7. Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG. PMID: 31287989; PMCID: PMC6703903.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    27. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2019 Feb 12; 10(1):52. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 30755264; PMCID: PMC6373121.
      View in: PubMed   Mentions:    Fields:    
    28. Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Curr Protoc Stem Cell Biol. 2018 08; 46(1):e56. Wilkinson DC, Mellody M, Meneses LK, Hope AC, Dunn B, Gomperts BN. PMID: 29927098; PMCID: PMC6105393.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    29. Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Res. 2018 04 15; 78(8):1986-1999. Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM. PMID: 29431637; PMCID: PMC5899686.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    30. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017 10 02; 8(1):217. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 28969679; PMCID: PMC5625837.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    31. Proceedings: Regenerative Medicine for Lung Diseases: A CIRM Workshop Report. Stem Cells Transl Med. 2017 10; 6(10):1823-1828. Kadyk LC, DeWitt ND, Gomperts B. PMID: 28791807; PMCID: PMC6430051.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    32. The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room. Cell Stem Cell. 2017 07 06; 21(1):1-3. Vijayaraj P, Gomperts BN. PMID: 28686859.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    33. Posttranslational modification of β-catenin is associated with pathogenic fibroblastic changes in bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2017 02 01; 312(2):L186-L195. Sucre JM, Vijayaraj P, Aros CJ, Wilkinson D, Paul M, Dunn B, Guttentag SH, Gomperts BN. PMID: 27941077; PMCID: PMC5336582.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Stem Cells Transl Med. 2017 02; 6(2):622-633. Wilkinson DC, Alva-Ornelas JA, Sucre JM, Vijayaraj P, Durra A, Richardson W, Jonas SJ, Paul MK, Karumbayaram S, Dunn B, Gomperts BN. PMID: 28191779; PMCID: PMC5442826.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    35. A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology. Am J Physiol Lung Cell Mol Physiol. 2016 05 15; 310(10):L889-98. Sucre JM, Wilkinson D, Vijayaraj P, Paul M, Dunn B, Alva-Ornelas JA, Gomperts BN. PMID: 26968771; PMCID: PMC4896099.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    36. Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA. Clin Cancer Res. 2015 Jun 01; 21(11):2440-4. Ooi AT, Gomperts BN. PMID: 25838393; PMCID: PMC4452440.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    37. Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling. Cell Stem Cell. 2014 Aug 07; 15(2):199-214. Paul MK, Bisht B, Darmawan DO, Chiou R, Ha VL, Wallace WD, Chon AT, Hegab AE, Grogan T, Elashoff DA, Alva-Ornelas JA, Gomperts BN. PMID: 24953182; PMCID: PMC4127166.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    38. Induction of multiciliated cells from induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6120-1. Gomperts BN. PMID: 24740182; PMCID: PMC4035920.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    39. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prev Res (Phila). 2014 May; 7(5):487-95. Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. PMID: 24618292; PMCID: PMC4059064.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    40. Aldehyde dehydrogenase activity enriches for proximal airway basal stem cells and promotes their proliferation. Stem Cells Dev. 2014 Mar 15; 23(6):664-75. Hegab AE, Ha VL, Bisht B, Darmawan DO, Ooi AT, Zhang KX, Paul MK, Kim YS, Gilbert JL, Attiga YS, Alva-Ornelas JA, Nickerson DW, Gomperts BN. PMID: 24171691; PMCID: PMC3938934.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    41. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18946-51. Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, Gomperts BN, Dubinett SM, Hayden P, Belinsky SA, Lenburg ME, Spira A. PMID: 24158479; PMCID: PMC3839685.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    42. Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prev Res (Phila). 2013 Jan; 6(1):4-7. Gomperts BN, Walser TC, Spira A, Dubinett SM. PMID: 23233734; PMCID: PMC3717378.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    43. Repair and regeneration of tracheal surface epithelium and submucosal glands in a mouse model of hypoxic-ischemic injury. Respirology. 2012 Oct; 17(7):1101-13. Hegab AE, Nickerson DW, Ha VL, Darmawan DO, Gomperts BN. PMID: 22617027; PMCID: PMC3723929.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    44. Isolation and in vitro characterization of basal and submucosal gland duct stem/progenitor cells from human proximal airways. Stem Cells Transl Med. 2012 Oct; 1(10):719-24. Hegab AE, Ha VL, Darmawan DO, Gilbert JL, Ooi AT, Attiga YS, Bisht B, Nickerson DW, Gomperts BN. PMID: 23197663; PMCID: PMC3659656.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    45. Isolation of basal cells and submucosal gland duct cells from mouse trachea. J Vis Exp. 2012 Sep 14; (67):e3731. Hegab AE, Ha VL, Attiga YS, Nickerson DW, Gomperts BN. PMID: 23007468; PMCID: PMC3490256.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    46. Identification of an interleukin 13-induced epigenetic signature in allergic airway inflammation. Am J Transl Res. 2012; 4(2):219-28. Ooi AT, Ram S, Kuo A, Gilbert JL, Yan W, Pellegrini M, Nickerson DW, Chatila TA, Gomperts BN. PMID: 22611474; PMCID: PMC3353532.
      View in: PubMed   Mentions: 20  
    47. Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential. Stem Cells. 2011 Aug; 29(8):1283-93. Hegab AE, Ha VL, Gilbert JL, Zhang KX, Malkoski SP, Chon AT, Darmawan DO, Bisht B, Ooi AT, Pellegrini M, Nickerson DW, Gomperts BN. PMID: 21710468; PMCID: PMC3403816.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    48. Evolving concepts in lung carcinogenesis. Semin Respir Crit Care Med. 2011 Feb; 32(1):32-43. Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM. PMID: 21500122; PMCID: PMC3423907.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    49. B-acute lymphoblastic leukemia and cystinuria in a patient with duplication 22q11.21 detected by chromosomal microarray analysis. Pediatr Blood Cancer. 2011 Mar; 56(3):470-3. Chang VY, Quintero-Rivera F, Baldwin EE, Woo K, Martinez-Agosto JA, Fu C, Gomperts BN. PMID: 21225931.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    50. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Res. 2010 Aug 15; 70(16):6639-48. Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, Walser TC, Wallace WD, Dubinett SM, Goodglick L, Gomperts BN. PMID: 20710044; PMCID: PMC2924777.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    51. Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection. Cancer Prev Res (Phila). 2010 Apr; 3(4):420-3. Gomperts BN, Spira A, Elashoff DE, Dubinett SM. PMID: 20332300.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    52. Quantification of cytokeratin 5 mRNA expression in the circulation of healthy human subjects and after lung transplantation. PLoS One. 2009 Jun 16; 4(6):e5925. Nickerson DW, Presson AP, Weigt SS, Gregson AL, Belperio JA, Gomperts BN. PMID: 19529775; PMCID: PMC2691992.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    53. Index of suspicion. Pediatr Rev. 2009 Jan; 30(1):15-21. Bekmezian A, Gomperts B, Weisleder P, Patraitis C, Thibodeau P, Parker-Mello K. PMID: 19118138.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Case 1: A limping child...with abdominal pain. Paediatr Child Health. 2008 Nov; 13(9):775-7. Bekmezian A, Gomperts B. PMID: 19436540; PMCID: PMC2603153.
      View in: PubMed   Mentions:
    55. Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation. Am J Transplant. 2008 Jul; 8(7):1512-22. Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch JP, Zisman DA, Belperio JA. PMID: 18513272; PMCID: PMC2760345.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    56. Circulating progenitor cells in chronic lung disease. Expert Rev Respir Med. 2007 Aug; 1(1):157-65. Mehrad B, Keane MP, Gomperts BN, Strieter RM. PMID: 20477275; PMCID: PMC3353522.
      View in: PubMed   Mentions: 2     Fields:    
    57. Fibrocytes in lung disease. J Leukoc Biol. 2007 Sep; 82(3):449-56. Gomperts BN, Strieter RM. PMID: 17550974.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    58. IL-13 regulates cilia loss and foxj1 expression in human airway epithelium. Am J Respir Cell Mol Biol. 2007 Sep; 37(3):339-46. Gomperts BN, Kim LJ, Flaherty SA, Hackett BP. PMID: 17541011; PMCID: PMC2720122.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    59. Keratinocyte growth factor improves repair in the injured tracheal epithelium. Am J Respir Cell Mol Biol. 2007 Jul; 37(1):48-56. Gomperts BN, Belperio JA, Fishbein MC, Keane MP, Burdick MD, Strieter RM. PMID: 17332441; PMCID: PMC1899348.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    60. The role of CXC chemokines in pulmonary fibrosis. J Clin Invest. 2007 Mar; 117(3):549-56. Strieter RM, Gomperts BN, Keane MP. PMID: 17332882; PMCID: PMC1804376.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    61. IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome. J Immunol. 2007 Jan 01; 178(1):511-9. Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, Strieter RM, Belperio JA. PMID: 17182591.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    62. Stem cells and chronic lung disease. Annu Rev Med. 2007; 58:285-98. Gomperts BN, Strieter RM. PMID: 16886904.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    63. Cancer CXC chemokine networks and tumour angiogenesis. Eur J Cancer. 2006 Apr; 42(6):768-78. Strieter RM, Burdick MD, Mestas J, Gomperts B, Keane MP, Belperio JA. PMID: 16510280.
      View in: PubMed   Mentions: 183     Fields:    Translation:Humans
    64. Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J Immunol. 2006 Feb 01; 176(3):1916-27. Gomperts BN, Belperio JA, Rao PN, Randell SH, Fishbein MC, Burdick MD, Strieter RM. PMID: 16424223.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    65. Chemokine-directed metastasis. Contrib Microbiol. 2006; 13:170-190. Gomperts BN, Strieter RM. PMID: 16627965.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    66. CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury. J Immunol. 2005 Nov 15; 175(10):6931-9. Belperio JA, Keane MP, Burdick MD, Gomperts BN, Xue YY, Hong K, Mestas J, Zisman D, Ardehali A, Saggar R, Lynch JP, Ross DJ, Strieter RM. PMID: 16272353.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    67. CXC chemokines in angiogenesis. Cytokine Growth Factor Rev. 2005 Dec; 16(6):593-609. Strieter RM, Burdick MD, Gomperts BN, Belperio JA, Keane MP. PMID: 16046180.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    68. Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome. J Clin Invest. 2005 May; 115(5):1150-62. Belperio JA, Keane MP, Burdick MD, Gomperts B, Xue YY, Hong K, Mestas J, Ardehali A, Mehrad B, Saggar R, Lynch JP, Ross DJ, Strieter RM. PMID: 15864347; PMCID: PMC1087179.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimals
    69. Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells. J Cell Sci. 2004 Mar 15; 117(Pt 8):1329-37. Gomperts BN, Gong-Cooper X, Hackett BP. PMID: 14996907.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    70. Gonococcal hand abscess. Pediatr Infect Dis J. 2000 Jul; 19(7):671-2. Gomperts BN, White LK. PMID: 10917235.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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